Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= T22B11_5
(3090 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|17542494|ref|NP_500617.1| dehydrogenase, E1 component and Tra... 2024 0.0
gi|7431585|pir||T15098 hypothetical protein T22B11.5 - Caenorhab... 2017 0.0
gi|39587634|emb|CAE58572.1| Hypothetical protein CBG01737 [Caeno... 1946 0.0
gi|31217266|ref|XP_316395.1| ENSANGP00000025238 [Anopheles gambi... 1187 0.0
gi|31217257|ref|XP_316393.1| ENSANGP00000013033 [Anopheles gambi... 1179 0.0
gi|31217270|ref|XP_316396.1| ENSANGP00000024901 [Anopheles gambi... 1160 0.0
gi|24665669|ref|NP_730223.1| CG11661-PA [Drosophila melanogaster... 1156 0.0
gi|48097079|ref|XP_391838.1| similar to ENSANGP00000013033 [Apis... 1155 0.0
gi|13436359|gb|AAH04964.1| OGDH protein [Homo sapiens] >gnl|BL_O... 1145 0.0
gi|28574590|ref|NP_788518.1| CG11661-PF [Drosophila melanogaster... 1142 0.0
gi|49118217|gb|AAH73213.1| Unknown (protein for MGC:80496) [Xeno... 1142 0.0
gi|38303923|gb|AAH61938.1| MGC68800 protein [Xenopus laevis] 1141 0.0
gi|49115318|gb|AAH73298.1| MGC68800 protein [Xenopus laevis] 1141 0.0
gi|15489120|gb|AAH13670.1| Ogdh protein [Mus musculus] 1138 0.0
gi|4505493|ref|NP_002532.1| oxoglutarate (alpha-ketoglutarate) d... 1136 0.0
gi|2160381|dbj|BAA06836.1| 2-oxoglutarate dehydrogenase [Homo sa... 1134 0.0
gi|34785384|gb|AAH57354.1| Ogdh protein [Mus musculus] 1128 0.0
gi|33563270|ref|NP_035086.1| oxoglutarate dehydrogenase (lipoami... 1125 0.0
gi|29421218|dbj|BAA86604.2| KIAA1290 protein [Homo sapiens] 1124 0.0
gi|8922716|ref|NP_060715.1| oxoglutarate dehydrogenase-like [Hom... 1121 0.0
gi|20072238|gb|AAH26320.1| Oxoglutarate dehydrogenase-like [Homo... 1118 0.0
gi|38075902|ref|XP_138959.3| similar to KIAA1290 protein [Mus mu... 1115 0.0
gi|47210299|emb|CAF94599.1| unnamed protein product [Tetraodon n... 1107 0.0
gi|34877017|ref|XP_214261.2| similar to KIAA1290 protein [Rattus... 1106 0.0
gi|50749142|ref|XP_421503.1| PREDICTED: similar to KIAA1290 prot... 1095 0.0
gi|47223283|emb|CAF98667.1| unnamed protein product [Tetraodon n... 1088 0.0
gi|47228548|emb|CAG05368.1| unnamed protein product [Tetraodon n... 1046 0.0
gi|283950|pir||A38234 oxoglutarate dehydrogenase (lipoamide) (EC... 1044 0.0
gi|24655383|ref|NP_728639.1| CG32316-PD [Drosophila melanogaster... 1031 0.0
gi|24655380|ref|NP_728638.1| CG32316-PB [Drosophila melanogaster... 1019 0.0
gi|49096496|ref|XP_409708.1| hypothetical protein AN5571.2 [Aspe... 926 0.0
gi|50259854|gb|EAL22522.1| hypothetical protein CNBB4000 [Crypto... 908 0.0
gi|32409599|ref|XP_325280.1| probable oxoglutarate dehydrogenase... 906 0.0
gi|16416078|emb|CAB91484.2| probable oxoglutarate dehydrogenase ... 906 0.0
gi|11252276|pir||T49683 probable oxoglutarate dehydrogenase prec... 905 0.0
gi|15239128|ref|NP_201376.1| 2-oxoglutarate dehydrogenase E1 com... 894 0.0
gi|34394039|dbj|BAC84070.1| putative 2-oxoglutarate dehydrogenas... 892 0.0
gi|11252274|pir||T50644 oxoglutarate dehydrogenase (lipoamide) (... 889 0.0
gi|30694242|ref|NP_191101.2| 2-oxoglutarate dehydrogenase E1 com... 882 0.0
gi|28416717|gb|AAO42889.1| At3g55410 [Arabidopsis thaliana] 881 0.0
gi|49076112|ref|XP_402067.1| hypothetical protein UM04452.1 [Ust... 881 0.0
gi|25012868|gb|AAN71522.1| RH09189p [Drosophila melanogaster] 874 0.0
gi|28574585|ref|NP_730226.2| CG11661-PE [Drosophila melanogaster... 874 0.0
gi|46116934|ref|XP_384485.1| conserved hypothetical protein [Gib... 872 0.0
gi|50425085|ref|XP_461134.1| unnamed protein product [Debaryomyc... 870 0.0
gi|46431876|gb|EAK91398.1| hypothetical protein CaO19.6165 [Cand... 868 0.0
gi|11252290|pir||T47680 probable oxoglutarate dehydrogenase (lip... 861 0.0
gi|19112564|ref|NP_595772.1| 2-oxoglutarate dehydrogenase e1 com... 859 0.0
gi|50288623|ref|XP_446741.1| unnamed protein product [Candida gl... 848 0.0
gi|50310525|ref|XP_455282.1| unnamed protein product [Kluyveromy... 829 0.0
gi|45190976|ref|NP_985230.1| AER374Cp [Eremothecium gossypii] >g... 825 0.0
gi|6322066|ref|NP_012141.1| alpha-ketoglutarate dehydrogenase; K... 824 0.0
gi|171785|gb|AAA34721.1| alpha-ketoglutarate dehydrogenase 816 0.0
gi|7431583|pir||T05894 probable oxoglutarate dehydrogenase (lipo... 808 0.0
gi|50554651|ref|XP_504734.1| hypothetical protein [Yarrowia lipo... 802 0.0
gi|23014366|ref|ZP_00054186.1| COG0567: 2-oxoglutarate dehydroge... 785 0.0
gi|46192007|ref|ZP_00007567.2| COG0567: 2-oxoglutarate dehydroge... 783 0.0
gi|48831909|ref|ZP_00288957.1| COG0567: 2-oxoglutarate dehydroge... 781 0.0
gi|48764978|ref|ZP_00269529.1| COG0567: 2-oxoglutarate dehydroge... 778 0.0
gi|1145803|gb|AAA86904.1| alpha-ketoglutarate dehydrogenase >gnl... 770 0.0
gi|22652788|gb|AAN03815.1| 2-oxoglutarate dehydrogenase E1 compo... 770 0.0
gi|45916778|ref|ZP_00195799.2| COG0567: 2-oxoglutarate dehydroge... 754 0.0
gi|27375563|ref|NP_767092.1| alpha-ketoglutarate dehydrogenase [... 753 0.0
gi|48141298|ref|XP_397207.1| similar to CG11661-PA [Apis mellifera] 752 0.0
gi|39933266|ref|NP_945542.1| putative alpha-ketoglutarate dehydr... 751 0.0
gi|1765991|gb|AAC44748.1| alpha-ketoglutarate dehydrogenase [Bra... 747 0.0
gi|16124594|ref|NP_419158.1| 2-oxoglutarate dehydrogenase, E1 co... 743 0.0
gi|15889891|ref|NP_355572.1| AGR_C_4776p [Agrobacterium tumefaci... 742 0.0
gi|15966806|ref|NP_387159.1| PROBABLE 2-OXOGLUTARATE DEHYDROGENA... 739 0.0
gi|13473636|ref|NP_105204.1| alpha-ketoglutarate dehydrogenase [... 732 0.0
gi|49474814|ref|YP_032856.1| Alpha-ketoglutarate dehydrogenase [... 726 0.0
gi|23502773|ref|NP_698900.1| 2-oxoglutarate dehydrogenase, E1 co... 725 0.0
gi|17986424|ref|NP_539058.1| 2-OXOGLUTARATE DEHYDROGENASE E1 COM... 723 0.0
gi|49476303|ref|YP_034344.1| Alpha-ketoglutarate dehydrogenase [... 723 0.0
gi|50404917|ref|YP_054009.1| 2-oxoglutarate dehydrogenase, putat... 714 0.0
gi|48851310|ref|ZP_00305552.1| COG0567: 2-oxoglutarate dehydroge... 706 0.0
gi|48729504|ref|ZP_00263254.1| COG0567: 2-oxoglutarate dehydroge... 706 0.0
gi|15596782|ref|NP_250276.1| 2-oxoglutarate dehydrogenase (E1 su... 705 0.0
gi|23103001|ref|ZP_00089494.1| COG0567: 2-oxoglutarate dehydroge... 705 0.0
gi|33597743|ref|NP_885386.1| 2-oxoglutarate dehydrogenase E1 com... 701 0.0
gi|33592259|ref|NP_879903.1| 2-oxoglutarate dehydrogenase E1 com... 701 0.0
gi|24213924|ref|NP_711405.1| 2-oxoglutarate dehydrogenase decarb... 699 0.0
gi|129036|sp|P20707|ODO1_AZOVI 2-oxoglutarate dehydrogenase E1 c... 697 0.0
gi|28869401|ref|NP_792020.1| 2-oxoglutarate dehydrogenase, E1 co... 697 0.0
gi|46310766|ref|ZP_00211388.1| COG0567: 2-oxoglutarate dehydroge... 695 0.0
gi|39997544|ref|NP_953495.1| 2-oxoglutarate dehydrogenase, E1 co... 694 0.0
gi|46318668|ref|ZP_00219106.1| COG0567: 2-oxoglutarate dehydroge... 693 0.0
gi|48769526|ref|ZP_00273871.1| COG0567: 2-oxoglutarate dehydroge... 692 0.0
gi|50085916|ref|YP_047426.1| 2-oxoglutarate decarboxylase, compo... 692 0.0
gi|46308512|ref|ZP_00210705.1| COG0567: 2-oxoglutarate dehydroge... 692 0.0
gi|48853408|ref|ZP_00307579.1| COG0567: 2-oxoglutarate dehydroge... 691 0.0
gi|2499407|sp|Q59106|ODO1_ALCEU 2-oxoglutarate dehydrogenase E1 ... 689 0.0
gi|26990881|ref|NP_746306.1| 2-oxoglutarate dehydrogenase, E1 co... 689 0.0
gi|15642087|ref|NP_231719.1| 2-oxoglutarate dehydrogenase, E1 co... 688 0.0
gi|37679216|ref|NP_933825.1| 2-oxoglutarate dehydrogenase comple... 687 0.0
gi|27363640|ref|NP_759168.1| 2-oxoglutarate dehydrogenase comple... 687 0.0
gi|23612809|ref|NP_704348.1| 2-oxoglutarate dehydrogenase e1 com... 686 0.0
gi|46912669|emb|CAG19459.1| putative 2-oxoglutarate dehydrogenas... 685 0.0
gi|48834500|ref|ZP_00291510.1| COG0567: 2-oxoglutarate dehydroge... 684 0.0
gi|16759675|ref|NP_455292.1| 2-oxoglutarate dehydrogenase E1 com... 684 0.0
gi|3219721|gb|AAC23516.1| alpha-ketoglutarate dehydrogenase; E1 ... 684 0.0
gi|37525384|ref|NP_928728.1| 2-oxoglutarate dehydrogenase E1 com... 683 0.0
gi|16764106|ref|NP_459721.1| 2-oxoglutarate dehydrogenase [Salmo... 682 0.0
gi|15830005|ref|NP_308778.1| 2-oxoglutarate dehydrogenase decarb... 682 0.0
gi|28897621|ref|NP_797226.1| 2-oxoglutarate dehydrogenase, E1 co... 682 0.0
gi|32041628|ref|ZP_00139211.1| COG0567: 2-oxoglutarate dehydroge... 681 0.0
gi|24111998|ref|NP_706508.1| 2-oxoglutarate dehydrogenase decarb... 680 0.0
gi|15800430|ref|NP_286442.1| 2-oxoglutarate dehydrogenase (decar... 680 0.0
gi|48788280|ref|ZP_00284259.1| COG0567: 2-oxoglutarate dehydroge... 680 0.0
gi|17545988|ref|NP_519390.1| PROBABLE OXOGLUTARATE DEHYDROGENASE... 680 0.0
gi|21242286|ref|NP_641868.1| oxoglutarate dehydrogenase [Xanthom... 679 0.0
gi|43019|emb|CAA25280.1| unnamed protein product [Escherichia co... 678 0.0
gi|23489985|gb|EAA21864.1| 2-oxoglutarate dehydrogenase, E1 comp... 674 0.0
gi|48844747|ref|ZP_00299046.1| COG0567: 2-oxoglutarate dehydroge... 674 0.0
gi|18149149|dbj|BAB83599.1| 2-oxoglutarate dehydrogenase [Pseudo... 674 0.0
gi|21230942|ref|NP_636859.1| oxoglutarate dehydrogenase [Xanthom... 673 0.0
gi|29418063|gb|AAO39689.1| 2-oxoglutarate dehydrogenase E1 compo... 673 0.0
gi|32475700|ref|NP_868694.1| alpha-ketoglutarate dehydrogenase E... 667 0.0
gi|47575379|ref|ZP_00245414.1| COG0567: 2-oxoglutarate dehydroge... 667 0.0
gi|16121413|ref|NP_404726.1| 2-oxoglutarate dehydrogenase E1 com... 667 0.0
gi|50120300|ref|YP_049467.1| 2-oxoglutarate dehydrogenase E1 com... 667 0.0
gi|30995467|ref|NP_439804.2| unknown protein [Haemophilus influe... 667 0.0
gi|15838151|ref|NP_298839.1| oxoglutarate dehydrogenase [Xylella... 667 0.0
gi|1073780|pir||E64135 oxoglutarate dehydrogenase (lipoamide) (E... 667 0.0
gi|28198666|ref|NP_778980.1| oxoglutarate dehydrogenase [Xylella... 666 0.0
gi|46133589|ref|ZP_00157430.2| COG0567: 2-oxoglutarate dehydroge... 666 0.0
gi|42521102|ref|NP_967017.1| 2-oxoglutarate dehydrogenase, E1 co... 665 0.0
gi|21223647|ref|NP_629426.1| putative 2-oxoglutarate dehydrogena... 665 0.0
gi|15602142|ref|NP_245214.1| SucA [Pasteurella multocida Pm70] >... 664 0.0
gi|22996772|ref|ZP_00041017.1| COG0567: 2-oxoglutarate dehydroge... 663 0.0
gi|46364406|ref|ZP_00227025.1| COG0567: 2-oxoglutarate dehydroge... 660 0.0
gi|15676848|ref|NP_273993.1| 2-oxoglutarate dehydrogenase, E1 co... 659 0.0
gi|15892150|ref|NP_359864.1| 2-oxoglutarate dehydrogenase e1 com... 659 0.0
gi|34580820|ref|ZP_00142300.1| 2-oxoglutarate dehydrogenase e1 c... 659 0.0
gi|24373494|ref|NP_717537.1| 2-oxoglutarate dehydrogenase, E1 co... 659 0.0
gi|48863228|ref|ZP_00317122.1| COG0567: 2-oxoglutarate dehydroge... 658 0.0
gi|46141556|ref|ZP_00146844.2| COG0567: 2-oxoglutarate dehydroge... 655 0.0
gi|34496526|ref|NP_900741.1| 2-oxoglutarate dehydrogenase E1 com... 654 0.0
gi|30250299|ref|NP_842369.1| Transketolase:Dehydrogenase, E1 com... 651 0.0
gi|15604055|ref|NP_220570.1| 2-OXOGLUTARATE DEHYDROGENASE E1 COM... 651 0.0
gi|29829514|ref|NP_824148.1| putative 2-oxoglutarate dehydrogena... 650 0.0
gi|23467323|ref|ZP_00122906.1| COG0567: 2-oxoglutarate dehydroge... 649 0.0
gi|32030042|ref|ZP_00132962.1| COG0567: 2-oxoglutarate dehydroge... 649 0.0
gi|29654692|ref|NP_820384.1| 2-oxoglutarate dehydrogenase, E1 co... 648 0.0
gi|32034767|ref|ZP_00134892.1| COG0567: 2-oxoglutarate dehydroge... 642 0.0
gi|31792441|ref|NP_854934.1| PROBABLE 2-OXOGLUTARATE DEHYDROGENA... 640 0.0
gi|15608388|ref|NP_215764.1| sucA [Mycobacterium tuberculosis H3... 639 0.0
gi|46131254|ref|ZP_00169384.2| COG0567: 2-oxoglutarate dehydroge... 639 0.0
gi|15840693|ref|NP_335730.1| 2-oxoglutarate dehydrogenase E1 com... 639 0.0
gi|46446724|ref|YP_008089.1| probable 2-oxoglutarate dehydrogena... 637 0.0
gi|33152413|ref|NP_873766.1| 2-oxoglutarate dehydrogenase E1 com... 635 e-180
gi|41408634|ref|NP_961470.1| SucA [Mycobacterium avium subsp. pa... 634 e-180
gi|46203354|ref|ZP_00051633.2| COG0567: 2-oxoglutarate dehydroge... 630 e-179
gi|1877028|dbj|BAA12222.1| 2-oxoglutarate dehydrogenase [Coryneb... 629 e-178
gi|38233597|ref|NP_939364.1| 2-oxoglutarate dehydrogenase, E1 an... 629 e-178
gi|23308830|ref|NP_600357.2| 2-oxoglutarate dehydrogenases, E1 c... 629 e-178
gi|15805318|ref|NP_294010.1| 2-oxoglutarate dehydrogenase, E1 co... 625 e-177
gi|15827539|ref|NP_301802.1| 2-oxoglutarate dehydrogenase, E1 an... 625 e-177
gi|25027746|ref|NP_737800.1| 2-oxoglutarate dehydrogenase E1 com... 622 e-176
gi|50842739|ref|YP_055966.1| 2-oxoglutarate dehydrogenase [Propi... 614 e-174
gi|28484290|ref|XP_140800.2| similar to KIAA1630 protein [Mus mu... 612 e-173
gi|50799468|ref|XP_424076.1| PREDICTED: similar to 2-oxoglutarat... 610 e-173
gi|40352990|gb|AAH64683.1| MGC68840 protein [Xenopus laevis] 610 e-173
gi|7248873|gb|AAF43700.1| 2-oxoglutarate dehydrogenase [Brucella... 609 e-172
gi|33519791|ref|NP_878623.1| 2-oxoglutarate dehydrogenase E1 com... 608 e-172
gi|46200000|ref|YP_005667.1| 2-oxoglutarate dehydrogenase E1 com... 604 e-171
gi|12803319|gb|AAH02477.1| Dehydrogenase E1 and transketolase do... 603 e-171
gi|38788380|ref|NP_061176.3| dehydrogenase E1 and transketolase ... 603 e-171
gi|26250844|ref|NP_756884.1| 2-oxoglutarate dehydrogenase E1 com... 602 e-170
gi|45532850|ref|ZP_00183848.1| COG0567: 2-oxoglutarate dehydroge... 602 e-170
gi|21672569|ref|NP_660636.1| 2-oxoglutarate dehydrogenase E1 com... 602 e-170
gi|39592196|emb|CAE75416.1| Hypothetical protein CBG23406 [Caeno... 601 e-170
gi|42524145|ref|NP_969525.1| oxoglutarate dehydrogenase [Bdellov... 601 e-170
gi|15616912|ref|NP_240125.1| 2-oxoglutarate dehydrogenase E1 com... 601 e-170
gi|641968|gb|AAA61785.1| alpha-ketoglutarate dehydrogenase 600 e-170
gi|34555852|emb|CAE46691.1| Hypothetical protein ZK836.2 [Caenor... 600 e-170
gi|17566920|ref|NP_506060.1| dehydrogenase E1 (5M685) [Caenorhab... 600 e-170
gi|22972289|ref|ZP_00019176.1| hypothetical protein [Chloroflexu... 598 e-169
gi|27904774|ref|NP_777900.1| oxoglutarate dehydrogenase [Buchner... 592 e-167
gi|10047337|dbj|BAB13456.1| KIAA1630 protein [Homo sapiens] 590 e-167
gi|30019405|ref|NP_831036.1| 2-oxoglutarate dehydrogenase E1 com... 589 e-166
gi|49479790|ref|YP_035493.1| 2-oxoglutarate dehydrogenase, E1 co... 587 e-166
gi|47569192|ref|ZP_00239879.1| 2-oxoglutarate dehydrogenase, E1 ... 587 e-166
gi|21399177|ref|NP_655162.1| E1_dehydrog, Dehydrogenase E1 compo... 585 e-165
gi|42780454|ref|NP_977701.1| 2-oxoglutarate dehydrogenase, E1 co... 585 e-165
gi|45547640|ref|ZP_00187684.1| COG0567: 2-oxoglutarate dehydroge... 583 e-165
gi|32491168|ref|NP_871422.1| sucA [Wigglesworthia glossinidia en... 580 e-164
gi|24651589|ref|NP_651849.1| CG1544-PA [Drosophila melanogaster]... 577 e-163
gi|15614769|ref|NP_243072.1| oxoglutarate dehydrogenase [Bacillu... 575 e-162
gi|47224441|emb|CAG08691.1| unnamed protein product [Tetraodon n... 575 e-162
gi|25012444|gb|AAN71328.1| RE22749p [Drosophila melanogaster] 574 e-162
gi|31203167|ref|XP_310532.1| ENSANGP00000017325 [Anopheles gambi... 572 e-161
gi|22995030|ref|ZP_00039515.1| COG0567: 2-oxoglutarate dehydroge... 570 e-161
gi|23098544|ref|NP_692010.1| oxoglutarate dehydrogenase E1 subun... 559 e-157
gi|13235417|emb|CAC33676.1| sucA [Rickettsia rickettsii] 555 e-156
gi|13235421|emb|CAC33613.1| sucA [Rickettsia montanensis] 555 e-156
gi|13235414|emb|CAC33736.1| sucA [Rickettsia typhi] 553 e-156
gi|49486254|ref|YP_043475.1| 2-oxoglutarate dehydrogenase E1 com... 550 e-155
gi|21283032|ref|NP_646120.1| oxoglutarate dehydrogenase [Staphyl... 549 e-154
gi|46395526|dbj|BAB57575.2| oxoglutarate dehydrogenase [Staphylo... 548 e-154
gi|49483603|ref|YP_040827.1| 2-oxoglutarate dehydrogenase E1 com... 548 e-154
gi|32399898|emb|CAD92196.1| 2-oxoglutarate dehydrogenase E1 [Sta... 546 e-154
gi|15926993|ref|NP_374526.1| 2-oxoglutarate dehydrogenase E1 [St... 545 e-153
gi|27468015|ref|NP_764652.1| 2-oxoglutarate dehydrogenase E1 [St... 543 e-152
gi|15924403|ref|NP_371937.1| oxoglutarate dehydrogenase [Staphyl... 540 e-152
gi|50812247|ref|NP_389819.2| 2-oxoglutarate dehydrogenase (E1 su... 532 e-149
gi|24651591|ref|NP_733420.1| CG1544-PB [Drosophila melanogaster]... 526 e-147
gi|129037|sp|P23129|ODO1_BACSU 2-oxoglutarate dehydrogenase E1 c... 525 e-147
gi|15618293|ref|NP_224578.1| Oxoglutarate Dehydrogenase [Chlamyd... 514 e-144
gi|29840182|ref|NP_829288.1| 2-oxoglutarate dehydrogenase, E1 co... 514 e-144
gi|15604773|ref|NP_219557.1| Oxoglutarate Dehydrogenase [Chlamyd... 506 e-141
gi|15834944|ref|NP_296703.1| 2-oxoglutarate dehydrogenase, E1 co... 501 e-140
gi|17549583|ref|NP_522923.1| PROBABLE 2-OXOGLUTARATE DEHYDROGENA... 499 e-139
gi|21391952|gb|AAM48330.1| GH08318p [Drosophila melanogaster] 443 e-122
gi|11252272|pir||T50617 hypothetical protein DKFZp762M115.1 - hu... 428 e-118
gi|20809820|gb|AAH29143.1| Ogdh protein [Mus musculus] 412 e-113
gi|19263628|gb|AAH25040.1| Ogdh protein [Mus musculus] 404 e-111
gi|21410557|gb|AAH31165.1| Ogdh protein [Mus musculus] 398 e-109
gi|41724322|ref|ZP_00151188.1| COG0567: 2-oxoglutarate dehydroge... 389 e-106
gi|790862|gb|AAA96485.1| putative 382 e-104
gi|50764328|ref|XP_422940.1| PREDICTED: similar to KIAA1630 prot... 380 e-103
gi|16307009|gb|AAH09580.1| OGDH protein [Homo sapiens] >gnl|BL_O... 375 e-102
gi|2660682|gb|AAB88080.1| oxoglutarate dehydrogenase [Burkholder... 372 e-101
gi|38524411|dbj|BAD02368.1| 2-oxoglutarate dehydrogenase [Barton... 370 e-100
gi|46189087|ref|ZP_00124265.2| COG0567: 2-oxoglutarate dehydroge... 333 1e-89
gi|34876831|ref|XP_341558.1| similar to KIAA1630 protein [Rattus... 333 2e-89
gi|26340786|dbj|BAC34055.1| unnamed protein product [Mus musculus] 331 6e-89
gi|50795147|ref|XP_423753.1| PREDICTED: similar to Dehydrogenase... 327 1e-87
gi|42629012|ref|ZP_00154562.1| COG0567: 2-oxoglutarate dehydroge... 311 8e-83
gi|48866809|ref|ZP_00320523.1| COG0567: 2-oxoglutarate dehydroge... 306 3e-81
gi|50808378|ref|XP_424588.1| PREDICTED: similar to MGC68840 prot... 285 6e-75
gi|45515445|ref|ZP_00167000.1| COG0567: 2-oxoglutarate dehydroge... 282 4e-74
gi|42453379|ref|ZP_00153286.1| hypothetical protein Rick022001 [... 249 4e-64
gi|143267|gb|AAA22628.1| 2-oxoglutarate dehydrogenase (odhA; EC ... 229 2e-58
gi|26418584|gb|AAN78226.1| alpha-ketoglutarate dehydrogenase [Ba... 219 3e-55
gi|48105931|ref|XP_396024.1| similar to ENSANGP00000017325 [Apis... 204 1e-50
gi|50511031|dbj|BAD32501.1| mKIAA1630 protein [Mus musculus] 196 3e-48
gi|48140341|ref|XP_393501.1| similar to Dehydrogenase E1 and tra... 184 1e-44
gi|48868189|ref|ZP_00321560.1| COG0567: 2-oxoglutarate dehydroge... 183 3e-44
gi|38174680|gb|AAH61232.1| Ogdh protein [Mus musculus] 182 6e-44
gi|3228684|gb|AAC23604.1| 2-oxoglutaric dehydrogenase [Brucella ... 175 7e-42
gi|2137104|pir||A41911 oxoglutarate dehydrogenase (lipoamide) (E... 168 8e-40
gi|45825115|gb|AAS77465.1| AT11348p [Drosophila melanogaster] 163 2e-38
gi|3747066|gb|AAC64174.1| 2-oxoglutarate dehydrogenase E1o compo... 146 3e-33
gi|495757|gb|AAA74135.1| 2-oxoglutarate dehydrogenase 129 4e-28
gi|24209808|gb|AAN39864.1| SucA protein [Salmonella typhi] >gnl|... 121 9e-26
gi|46189088|ref|ZP_00205905.1| hypothetical protein Psyr020587 [... 96 4e-18
gi|3169332|gb|AAC17864.1| OdhA [Bacillus subtilis] 96 7e-18
gi|50808405|ref|XP_428964.1| PREDICTED: similar to MGC68840 prot... 88 1e-15
gi|31217263|ref|XP_316394.1| ENSANGP00000023593 [Anopheles gambi... 77 3e-12
gi|37589737|gb|AAH59621.1| Zgc:73296 protein [Danio rerio] 71 1e-10
gi|23502007|ref|NP_698134.1| pyruvate dehydrogenase complex, E1 ... 65 1e-08
gi|482967|pir||B38234 oxoglutarate dehydrogenase (lipoamide) (EC... 65 1e-08
gi|49475368|ref|YP_033409.1| Pyruvate dehydrogenase E1 component... 64 2e-08
gi|17987137|ref|NP_539771.1| PYRUVATE DEHYDROGENASE E1 COMPONENT... 64 3e-08
gi|49474127|ref|YP_032169.1| Pyruvate dehydrogenase E1 component... 62 8e-08
gi|2252568|emb|CAA74089.1| 2-oxogluterate dehydrogenase [Shewane... 57 3e-06
gi|45917129|ref|ZP_00196269.2| COG1071: Pyruvate/2-oxoglutarate ... 57 4e-06
gi|15965198|ref|NP_385551.1| PYRUVATE DEHYDROGENASE ALPHA2 SUBUN... 56 5e-06
gi|15888754|ref|NP_354435.1| AGR_C_2636p [Agrobacterium tumefaci... 55 1e-05
gi|17935329|ref|NP_532119.1| pyruvate dehydrogenase alpha subuni... 55 1e-05
gi|48764305|ref|ZP_00268857.1| COG1071: Pyruvate/2-oxoglutarate ... 53 4e-05
gi|13470619|ref|NP_102188.1| pyruvate dehydrogenase E1 alpha sub... 53 4e-05
gi|7431584|pir||S70799 oxoglutarate dehydrogenase (lipoamide) (E... 53 4e-05
gi|50417951|gb|AAH77220.1| Unknown (protein for MGC:79036) [Xeno... 52 1e-04
gi|129048|sp|P26267|ODPA_ASCSU Pyruvate dehydrogenase E1 compone... 51 2e-04
gi|345334|pir||A45608 pyruvate dehydrogenase (lipoamide) (EC 1.2... 51 2e-04
gi|129051|sp|P26268|ODPT_ASCSU Pyruvate dehydrogenase E1 compone... 50 3e-04
gi|50257528|gb|EAL20233.1| hypothetical protein CNBF0450 [Crypto... 50 3e-04
gi|38110720|gb|EAA56400.1| hypothetical protein MG06371.4 [Magna... 49 6e-04
gi|6679263|ref|NP_032837.1| pyruvate dehydrogenase E1 alpha 2; p... 49 7e-04
gi|12839413|dbj|BAB24543.1| unnamed protein product [Mus musculus] 49 7e-04
gi|4204872|gb|AAD11551.1| pyruvate dehydrogenase E1 alpha subuni... 49 7e-04
gi|27379894|ref|NP_771423.1| pyruvate dehydrogenase alpha subuni... 48 0.001
gi|50539866|ref|NP_001002399.1| zgc:92705 [Danio rerio] >gnl|BL_... 47 0.002
gi|16758900|ref|NP_446446.1| pyruvate dehydrogenase E1 alpha-lik... 47 0.002
gi|8474180|sp|O66112|ODPA_ZYMMO Pyruvate dehydrogenase E1 compon... 47 0.003
gi|46308912|ref|ZP_00211104.1| COG1071: Pyruvate/2-oxoglutarate ... 46 0.005
gi|15805070|ref|NP_293755.1| 2-oxo acid dehydrogenase, E1 compon... 46 0.006
gi|46122153|ref|XP_385630.1| conserved hypothetical protein [Gib... 45 0.011
gi|48855343|ref|ZP_00309502.1| COG1071: Pyruvate/2-oxoglutarate ... 45 0.014
gi|19746010|ref|NP_607146.1| putative acetoin dehydrogenase (TPP... 44 0.018
gi|15675025|ref|NP_269199.1| putative acetoin dehydrogenase (TPP... 44 0.018
gi|20806712|ref|NP_621883.1| Thiamine pyrophosphate-dependent de... 44 0.018
gi|28896104|ref|NP_802454.1| putative acetoin dehydrogenase (TPP... 44 0.018
gi|37362644|ref|NP_011105.2| alpha subunit of pyruvate dehydroge... 44 0.018
gi|172108|gb|AAA34847.1| pyruvate dehydrogenase precursor (EC 1.... 44 0.018
gi|1070438|pir||DEBYPA pyruvate dehydrogenase (lipoamide) (EC 1.... 44 0.018
gi|39997538|ref|NP_953489.1| dehydrogenase complex, E1 component... 44 0.018
gi|7465697|pir||T33722 probable pyruvate dehydrogenase (lipoamid... 44 0.031
gi|50311201|ref|XP_455624.1| ODPA_KLULA [Kluyveromyces lactis] >... 44 0.031
gi|2148094|pir||I40790 acetoin dehydrogenase (TPP-dependent) (EC... 43 0.041
gi|31228258|ref|XP_318026.1| ENSANGP00000010866 [Anopheles gambi... 43 0.041
gi|46202886|ref|ZP_00208699.1| COG1071: Pyruvate/2-oxoglutarate ... 43 0.041
gi|42520291|ref|NP_966206.1| pyruvate dehydrogenase complex, E1 ... 43 0.053
gi|47575710|ref|NP_001001197.1| hypothetical protein MGC75605 [X... 43 0.053
gi|15829235|ref|NP_326595.1| PYRUVATE DEHYDROGENASE E1 COMPONENT... 42 0.069
gi|2623175|gb|AAB86816.1| pyruvate dehydrogenase E1 component al... 42 0.091
gi|50293763|ref|XP_449293.1| unnamed protein product [Candida gl... 42 0.091
gi|47459419|ref|YP_016281.1| pyruvate dehydrogenase E1 component... 42 0.091
gi|29375920|ref|NP_815074.1| pyruvate dehydrogenase complex E1 c... 42 0.12
gi|50555213|ref|XP_505015.1| hypothetical protein [Yarrowia lipo... 42 0.12
gi|31228371|ref|XP_318043.1| ENSANGP00000003422 [Anopheles gambi... 42 0.12
gi|48823809|ref|ZP_00285292.1| COG1071: Pyruvate/2-oxoglutarate ... 41 0.15
gi|46437028|gb|EAK96381.1| hypothetical protein CaO19.3097 [Cand... 41 0.15
gi|22971075|ref|ZP_00018071.1| hypothetical protein [Chloroflexu... 41 0.20
gi|31205789|ref|XP_311846.1| ENSANGP00000018271 [Anopheles gambi... 41 0.20
gi|50770707|ref|XP_427090.1| PREDICTED: similar to MGC68840 prot... 40 0.26
gi|12045130|ref|NP_072941.1| pyruvate dehydrogenase component E1... 40 0.26
gi|28493756|ref|NP_787917.1| pyruvate dehydrogenase E1 component... 40 0.34
gi|162640|gb|AAA51410.1| branched chain alpha-keto acid dehydrog... 40 0.34
gi|27806223|ref|NP_776932.1| branched chain keto acid dehydrogen... 40 0.34
gi|38344868|emb|CAE01294.2| OSJNBa0020P07.11 [Oryza sativa (japo... 40 0.34
gi|15613339|ref|NP_241642.1| acetoin dehydrogenase (TPP-dependen... 39 0.59
gi|27468116|ref|NP_764753.1| branched-chain alpha-keto acid dehy... 39 0.59
gi|23023606|ref|ZP_00062839.1| COG1071: Pyruvate/2-oxoglutarate ... 39 0.59
gi|34541111|ref|NP_905590.1| ATPase, putative [Porphyromonas gin... 39 0.77
gi|32411713|ref|XP_326337.1| hypothetical protein [Neurospora cr... 39 0.77
gi|45548501|ref|ZP_00188533.1| COG1071: Pyruvate/2-oxoglutarate ... 39 0.77
gi|30022243|ref|NP_833874.1| 2-oxoisovalerate dehydrogenase alph... 39 1.0
gi|50426983|ref|XP_462096.1| unnamed protein product [Debaryomyc... 39 1.0
gi|15614385|ref|NP_242688.1| acetoin dehydrogenase E1 component ... 39 1.0
gi|47216013|emb|CAF96261.1| unnamed protein product [Tetraodon n... 39 1.0
gi|23500271|ref|NP_699711.1| 2-oxoisovalerate dehydrogenase E1 c... 38 1.3
gi|48852300|ref|ZP_00306488.1| COG0022: Pyruvate/2-oxoglutarate ... 38 1.7
gi|17989093|ref|NP_541726.1| 2-OXOISOVALERATE DEHYDROGENASE ALPH... 38 1.7
gi|48844521|ref|ZP_00298828.1| COG1071: Pyruvate/2-oxoglutarate ... 38 1.7
gi|47459418|ref|YP_016280.1| pyruvate dehydrogenase E1 component... 37 2.2
gi|27366905|ref|NP_762432.1| Pyruvate/2-oxoglutarate dehydrogena... 37 2.2
gi|37676681|ref|NP_937077.1| putative pyruvate dehydrogenase E1 ... 37 2.2
gi|6979690|gb|AAF34600.1| Irb5 [Vibrio cholerae] 37 2.2
gi|47093759|ref|ZP_00231509.1| 2-oxoisovalerate dehydrogenase E1... 37 2.2
gi|26553960|ref|NP_757894.1| pyruvate dehydrogenase E1 component... 37 2.2
gi|21402214|ref|NP_658199.1| E1_dehydrog, Dehydrogenase E1 compo... 37 2.9
gi|16803412|ref|NP_464897.1| similar to branched-chain alpha-ket... 37 2.9
gi|46907598|ref|YP_013987.1| 2-oxoisovalerate dehydrogenase E1 c... 37 2.9
gi|48103232|ref|XP_395531.1| similar to ENSANGP00000010866 [Apis... 37 3.8
gi|42783280|ref|NP_980527.1| 3-methyl-2-oxobutanoate dehydrogena... 37 3.8
gi|21307824|gb|AAL34978.1| pyruvate dehydrogenase E1-alpha subun... 37 3.8
gi|16800477|ref|NP_470745.1| similar to branched-chain alpha-ket... 37 3.8
gi|39998110|ref|NP_954061.1| dehydrogenase, E1 component, alpha ... 37 3.8
gi|20807175|ref|NP_622346.1| Thiamine pyrophosphate-dependent de... 36 5.0
gi|31544689|ref|NP_853267.1| AcoA [Mycoplasma gallisepticum R] >... 36 5.0
gi|21733727|emb|CAD27919.1| branched chain keto acid dehydrogena... 36 6.5
gi|47169248|pdb|1UM9|B Chain B, Branched-Chain 2-Oxo Acid Dehydr... 36 6.5
gi|23099321|ref|NP_692787.1| branched-chain alpha-keto acid dehy... 36 6.5
gi|14601551|ref|NP_148091.1| pyruvate dehydrogenase E1 component... 35 8.5
gi|50590329|ref|ZP_00331722.1| COG1071: Pyruvate/2-oxoglutarate ... 35 8.5
gi|16077873|ref|NP_388687.1| acetoin dehydrogenase E1 component ... 35 8.5
gi|15228333|ref|NP_187670.1| myb family transcription factor [Ar... 35 8.5
gi|48858461|ref|ZP_00312415.1| COG0796: Glutamate racemase [Clos... 35 8.5
gi|22652783|gb|AAN03811.1| pyruvate dehydrogenase E1 component a... 35 8.5
>gi|17542494|ref|NP_500617.1| dehydrogenase, E1 component and
Transketolase, central region (115.7 kD) (4F462)
[Caenorhabditis elegans]
gi|14916356|gb|AAB94185.2| Hypothetical protein T22B11.5
[Caenorhabditis elegans]
Length = 1029
Score = 2024 bits (5245), Expect = 0.0
Identities = 1005/1029 (97%), Positives = 1005/1029 (97%)
Frame = -1
Query: 3090 MHRASLICRLASPSRINAIRNASSGKSHISASTLVQHRNQSVAAAVKHEPFLNGSSSIYI 2911
MHRASLICRLASPSRINAIRNASSGKSHISASTLVQHRNQSVAAAVKHEPFLNGSSSIYI
Sbjct: 1 MHRASLICRLASPSRINAIRNASSGKSHISASTLVQHRNQSVAAAVKHEPFLNGSSSIYI 60
Query: 2910 EQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVTTSS 2731
EQMYEAWLQDPSSVHTSWDAYFRNVE AYAGALGVSPAAAQVTTSS
Sbjct: 61 EQMYEAWLQDPSSVHTSWDAYFRNVEAGAGPGQAFQAPPATAYAGALGVSPAAAQVTTSS 120
Query: 2730 APATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSF 2551
APATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSF
Sbjct: 121 APATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSF 180
Query: 2550 YGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIR 2371
YGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIR
Sbjct: 181 YGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIR 240
Query: 2370 RRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVID 2191
RRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVID
Sbjct: 241 RRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVID 300
Query: 2190 SSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVKYHLGVCIE 2011
SSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVKYHLGVCIE
Sbjct: 301 SSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVKYHLGVCIE 360
Query: 2010 RLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAG 1831
RLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAG
Sbjct: 361 RLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAG 420
Query: 1830 QGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVN 1651
QGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVN
Sbjct: 421 QGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVN 480
Query: 1650 VDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTA 1471
VDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTA
Sbjct: 481 VDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTA 540
Query: 1470 LEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKR 1291
LEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKR
Sbjct: 541 LEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKR 600
Query: 1290 DPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKDNSLDWACGEALA 1111
DPLKLPSTG IGKFSQYPEGFNLHRGLERTLKGRQQMLKDNSLDWACGEALA
Sbjct: 601 DPLKLPSTGIEQENIEQIIGKFSQYPEGFNLHRGLERTLKGRQQMLKDNSLDWACGEALA 660
Query: 1110 FGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSL 931
FGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSL
Sbjct: 661 FGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSL 720
Query: 930 SEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLP 751
SEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLP
Sbjct: 721 SEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLP 780
Query: 750 HGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANI 571
HGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANI
Sbjct: 781 HGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANI 840
Query: 570 YHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDV 391
YHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDV
Sbjct: 841 YHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDV 900
Query: 390 KRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQE 211
KRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQE
Sbjct: 901 KRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQE 960
Query: 210 EHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGVP 31
EHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGVP
Sbjct: 961 EHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGVP 1020
Query: 30 KSKLEGFKA 4
KSKLEGFKA
Sbjct: 1021 KSKLEGFKA 1029
>gi|7431585|pir||T15098 hypothetical protein T22B11.5 - Caenorhabditis
elegans
Length = 1038
Score = 2017 bits (5225), Expect = 0.0
Identities = 1005/1038 (96%), Positives = 1005/1038 (96%), Gaps = 9/1038 (0%)
Frame = -1
Query: 3090 MHRASLICRLASPSRINAIRNASSGKSHISASTLVQ---------HRNQSVAAAVKHEPF 2938
MHRASLICRLASPSRINAIRNASSGKSHISASTLVQ HRNQSVAAAVKHEPF
Sbjct: 1 MHRASLICRLASPSRINAIRNASSGKSHISASTLVQVVTKNSKKLHRNQSVAAAVKHEPF 60
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVE AYAGALGVSP
Sbjct: 61 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEAGAGPGQAFQAPPATAYAGALGVSP 120
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 2578
AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT
Sbjct: 121 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 180
Query: 2577 IPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLN 2398
IPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLN
Sbjct: 181 IPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLN 240
Query: 2397 NLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVL 2218
NLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVL
Sbjct: 241 NLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVL 300
Query: 2217 IPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDV 2038
IPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDV
Sbjct: 301 IPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDV 360
Query: 2037 KYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAIL 1858
KYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAIL
Sbjct: 361 KYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAIL 420
Query: 1857 LHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRV 1678
LHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRV
Sbjct: 421 LHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRV 480
Query: 1677 VGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMY 1498
VGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMY
Sbjct: 481 VGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMY 540
Query: 1497 QRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDS 1318
QRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDS
Sbjct: 541 QRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDS 600
Query: 1317 PWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKDNSL 1138
PWDDFFKKRDPLKLPSTG IGKFSQYPEGFNLHRGLERTLKGRQQMLKDNSL
Sbjct: 601 PWDDFFKKRDPLKLPSTGIEQENIEQIIGKFSQYPEGFNLHRGLERTLKGRQQMLKDNSL 660
Query: 1137 DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQG 958
DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQG
Sbjct: 661 DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQG 720
Query: 957 EYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIR 778
EYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIR
Sbjct: 721 EYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIR 780
Query: 777 QSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIV 598
QSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIV
Sbjct: 781 QSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIV 840
Query: 597 ANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETG 418
ANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETG
Sbjct: 841 ANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETG 900
Query: 417 APSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQ 238
APSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQ
Sbjct: 901 APSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQ 960
Query: 237 GAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKE 58
GAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKE
Sbjct: 961 GAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKE 1020
Query: 57 MMSKVFGVPKSKLEGFKA 4
MMSKVFGVPKSKLEGFKA
Sbjct: 1021 MMSKVFGVPKSKLEGFKA 1038
>gi|39587634|emb|CAE58572.1| Hypothetical protein CBG01737
[Caenorhabditis briggsae]
Length = 1027
Score = 1946 bits (5042), Expect = 0.0
Identities = 963/1030 (93%), Positives = 988/1030 (95%), Gaps = 1/1030 (0%)
Frame = -1
Query: 3090 MHRASLICRLASPSRINAIRNASS-GKSHISASTLVQHRNQSVAAAVKHEPFLNGSSSIY 2914
MHRASLICRLASPSRIN+IR+ASS G + ISA+ LVQ R QSVAA+VKHEPFLNGSSS+Y
Sbjct: 1 MHRASLICRLASPSRINSIRSASSYGNNTISATPLVQQRKQSVAASVKHEPFLNGSSSVY 60
Query: 2913 IEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVTTS 2734
IEQMYE WL++PSSVHTSWDAYFRNVE AYAG++GV A TS
Sbjct: 61 IEQMYETWLENPSSVHTSWDAYFRNVEAGAGPGQAFQAPPSVAYAGSMGVPSAPI---TS 117
Query: 2733 SAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELS 2554
+APATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELS
Sbjct: 118 AAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELS 177
Query: 2553 FYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWI 2374
FYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLK+IYCTSTGVEYMHLNNLEQQDWI
Sbjct: 178 FYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKEIYCTSTGVEYMHLNNLEQQDWI 237
Query: 2373 RRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVI 2194
RRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPA+KQVI
Sbjct: 238 RRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAIKQVI 297
Query: 2193 DSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVKYHLGVCI 2014
DSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVKYHLGVCI
Sbjct: 298 DSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVKYHLGVCI 357
Query: 2013 ERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFA 1834
ERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFA
Sbjct: 358 ERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFA 417
Query: 1833 GQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHV 1654
GQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHV
Sbjct: 418 GQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHV 477
Query: 1653 NVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKT 1474
NVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKT
Sbjct: 478 NVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKT 537
Query: 1473 ALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKK 1294
ALEKYQEKILNEGVANEQYVKEELTKYG+ILEDAYENAQKVTYVRNRDWLDSPWDDFFKK
Sbjct: 538 ALEKYQEKILNEGVANEQYVKEELTKYGAILEDAYENAQKVTYVRNRDWLDSPWDDFFKK 597
Query: 1293 RDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKDNSLDWACGEAL 1114
RDPLKLPSTG IGKF YPEGFNLHRGLERTLKGRQQMLKDNSLDWACGEAL
Sbjct: 598 RDPLKLPSTGIEQENIEHIIGKFGSYPEGFNLHRGLERTLKGRQQMLKDNSLDWACGEAL 657
Query: 1113 AFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSS 934
AFGSLLKEGIHVRLSGQDV+RGTFSHRHHVLHDQKVDQKIYNPLNDL++ QGEYTVCNSS
Sbjct: 658 AFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQKVDQKIYNPLNDLADPQGEYTVCNSS 717
Query: 933 LSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLL 754
LSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQF+SSGQSKWIRQSGLVMLL
Sbjct: 718 LSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFVSSGQSKWIRQSGLVMLL 777
Query: 753 PHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPAN 574
PHGYEGMGPEHSSARPERFLQMCNEDDEIDL+KIAF GTFEAQQLHDTNWIVANCTTPAN
Sbjct: 778 PHGYEGMGPEHSSARPERFLQMCNEDDEIDLDKIAFGGTFEAQQLHDTNWIVANCTTPAN 837
Query: 573 IYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPD 394
IYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQR+IPETGAPSQNPP+
Sbjct: 838 IYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRIIPETGAPSQNPPN 897
Query: 393 VKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQ 214
V+R+VFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEI+WAQ
Sbjct: 898 VQRLVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEIIWAQ 957
Query: 213 EEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGV 34
EEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNK+THMQEQKEMMSKVFGV
Sbjct: 958 EEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKYTHMQEQKEMMSKVFGV 1017
Query: 33 PKSKLEGFKA 4
PKSKLEGFKA
Sbjct: 1018 PKSKLEGFKA 1027
>gi|31217266|ref|XP_316395.1| ENSANGP00000025238 [Anopheles gambiae]
gi|30176027|gb|EAA44211.1| ENSANGP00000025238 [Anopheles gambiae str.
PEST]
Length = 1013
Score = 1187 bits (3072), Expect = 0.0
Identities = 598/1024 (58%), Positives = 738/1024 (71%), Gaps = 11/1024 (1%)
Frame = -1
Query: 3090 MHRASLICRLASPSRINAI------RNASSGKSHISASTLVQHRNQSVAAAVKHEPFLNG 2929
MHRA + +P + AS + + A++ V+ N + A EPFLNG
Sbjct: 1 MHRARTALHMVNPMGQQNFGSFLLKKQASKLTTELVAASSVKLYNSAAA-----EPFLNG 55
Query: 2928 SSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS-PAA 2752
SSS YI+ MY AWL+DP+SVH SWDAYFRN A LG S PA
Sbjct: 56 SSSNYIDDMYNAWLRDPASVHASWDAYFRNNSYAAPPSLAPVPKNHVPAAQYLGSSLPAV 115
Query: 2751 AQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIP 2572
A +A R+D I DHL +Q +IRSYQ RGHN+A LDPLGINSADLDD P
Sbjct: 116 AGA--GAAVGGRIDDKL----IDDHLAVQAIIRSYQIRGHNVARLDPLGINSADLDDKTP 169
Query: 2571 PELELSFYGLGERDLDREFLLPPTTFISEK-KSLTLREILQRLKDIYCTSTGVEYMHLNN 2395
PEL S Y E D++R F LP TTFI K K L LREIL RL+ YC GVE+M +N+
Sbjct: 170 PELLYSSYRFEEADMERVFKLPSTTFIGGKEKFLPLREILGRLEKAYCNKIGVEFMFINS 229
Query: 2394 LEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLI 2215
LEQ +WIR RFE P + ++++K+++ RL R+T FE FLAKK+ SEKRFGLEGCE++I
Sbjct: 230 LEQCNWIRERFETPNIMTYTNEEKRLILARLTRATGFEAFLAKKFSSEKRFGLEGCEIMI 289
Query: 2214 PAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVK 2035
PAMK+VID S+ LGV+S ++GMPHRGRLNVLANVCR+PL I +QF+ LE AD+GSGDVK
Sbjct: 290 PAMKEVIDVSTRLGVESIIMGMPHRGRLNVLANVCRKPLHQIFTQFAGLEAADDGSGDVK 349
Query: 2034 YHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILL 1855
YHLG IERLNR + KN+++AVVANPSHLEAVDPVV GK RAE FY GD + + M+ILL
Sbjct: 350 YHLGTYIERLNRVTNKNIRLAVVANPSHLEAVDPVVQGKTRAEQFYRGDGEGKKVMSILL 409
Query: 1854 HGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVV 1675
HGDAAF GQGVV ET +L DLP YTTHG IHIVVNNQIGFTTDPR SRSSPYCTDV RVV
Sbjct: 410 HGDAAFCGQGVVFETMHLSDLPDYTTHGTIHIVVNNQIGFTTDPRHSRSSPYCTDVARVV 469
Query: 1674 GCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQ 1495
PIFHVN DDPEAVMHVC VAA+WR TF KDVI+D+V YRR+GHNE+DEPMFTQPLMY+
Sbjct: 470 NAPIFHVNGDDPEAVMHVCKVAAEWRATFHKDVIIDIVSYRRNGHNEIDEPMFTQPLMYK 529
Query: 1494 RIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSP 1315
+I+ TK AL+ Y +++ EGV + VK KY I E+A+E A+ T+++ +DW+DSP
Sbjct: 530 KIRGTKPALDIYANQLITEGVVTAEEVKSVKDKYEKICEEAFEQAKIETHIKYKDWIDSP 589
Query: 1314 WDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEG---FNLHRGLERTLKGRQQMLKDN 1144
W FF+ +DPLK+ TG +FS P F +H+GL R L R++ML++
Sbjct: 590 WSGFFEGKDPLKVAPTGVIEETLVHIGNRFSSPPPNAAEFVIHKGLLRVLAARKEMLENK 649
Query: 1143 SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEG 964
++DWA EA+AFGSLLKEGIHVRLSGQDV+RGTFSHRHHVLH Q VD+ Y PL L
Sbjct: 650 TIDWALAEAMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHHQTVDKATYRPLCHLYPD 709
Query: 963 QGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKW 784
Q YTVCNSSLSE+ VLGFELGYSM +PN+LV WEAQFGDF+NTAQCIIDQF+SSGQ+KW
Sbjct: 710 QAPYTVCNSSLSEFGVLGFELGYSMTNPNALVCWEAQFGDFNNTAQCIIDQFVSSGQAKW 769
Query: 783 IRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNW 604
+RQSGLVMLLPHG EGMGPEHSSAR ERFLQMC++D + + F +QLHD NW
Sbjct: 770 VRQSGLVMLLPHGMEGMGPEHSSARVERFLQMCSDDPDYFPPE---SEEFAIRQLHDINW 826
Query: 603 IVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPE 424
IVANC+TP N +HLLRRQ+ +PFRKP +V +PKSLLRHP RS + G+ F+R+IP+
Sbjct: 827 IVANCSTPGNYFHLLRRQIALPFRKPLIVLTPKSLLRHPECRSNFSEMTDGTEFKRLIPD 886
Query: 423 TGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRK 244
++NP VKRV+FCTG+VYYD++ AR+ ++D+A+ R+EQ+SPFPYDLV+ EC K
Sbjct: 887 -ALTAENPNQVKRVIFCTGRVYYDLLKARRDRKLDHDIAISRIEQISPFPYDLVKAECAK 945
Query: 243 YQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQ 64
Y AE++WAQEEHKN G W++VQPR ++ ++ R Y GR +S ATG+K H++E
Sbjct: 946 YPNAELVWAQEEHKNQGCWTYVQPRFDTAIN-STRDFSYVGRPCGASTATGSKAQHLKEL 1004
Query: 63 KEMM 52
K ++
Sbjct: 1005 KNLL 1008
>gi|31217257|ref|XP_316393.1| ENSANGP00000013033 [Anopheles gambiae]
gi|21298668|gb|EAA10813.1| ENSANGP00000013033 [Anopheles gambiae str.
PEST]
Length = 1043
Score = 1179 bits (3051), Expect = 0.0
Identities = 599/1044 (57%), Positives = 740/1044 (70%), Gaps = 31/1044 (2%)
Frame = -1
Query: 3090 MHRASLICRLASPSRINAI------RNASSGKSHISASTLVQHRNQSVAAAVKHEPFLNG 2929
MHRA + +P + AS + + A++ V+ N + A EPFLNG
Sbjct: 10 MHRARTALHMVNPMGQQNFGSFLLKKQASKLTTELVAASSVKLYNSAAA-----EPFLNG 64
Query: 2928 SSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS-PAA 2752
SSS YI+ MY AWL+DP+SVH SWDAYFRN A LG S PA
Sbjct: 65 SSSNYIDDMYNAWLRDPASVHASWDAYFRNNSYAAPPSLAPVPKNHVPAAQYLGSSLPAV 124
Query: 2751 AQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIP 2572
A +A R+D I DHL +Q +IRSYQ RGHN+A LDPLGINSADLDD P
Sbjct: 125 AGA--GAAVGGRIDDKL----IDDHLAVQAIIRSYQIRGHNVARLDPLGINSADLDDKTP 178
Query: 2571 PELELSFY--------------------GLGERDLDREFLLPPTTFISEK-KSLTLREIL 2455
PEL S Y G+ E D++R F LP TTFI K K L LREIL
Sbjct: 179 PELLYSSYRFVHQRILECVSNEDRQLLLGMKEADMERVFKLPSTTFIGGKEKFLPLREIL 238
Query: 2454 QRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEF 2275
RL+ YC GVE+M +N+LEQ +WIR RFE P + ++++K+++ RL R+T FE F
Sbjct: 239 GRLEKAYCNKIGVEFMFINSLEQCNWIRERFETPNIMTYTNEEKRLILARLTRATGFEAF 298
Query: 2274 LAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLA 2095
LAKK+ SEKRFGLEGCE++IPAMK+VID S+ LGV+S ++GMPHRGRLNVLANVCR+PL
Sbjct: 299 LAKKFSSEKRFGLEGCEIMIPAMKEVIDVSTRLGVESIIMGMPHRGRLNVLANVCRKPLH 358
Query: 2094 TILSQFSTLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKV 1915
I +QF+ LE AD+GSGDVKYHLG IERLNR + KN+++AVVANPSHLEAVDPVV GK
Sbjct: 359 QIFTQFAGLEAADDGSGDVKYHLGTYIERLNRVTNKNIRLAVVANPSHLEAVDPVVQGKT 418
Query: 1914 RAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGF 1735
RAE FY GD + + M+ILLHGDAAF GQGVV ET +L DLP YTTHG IHIVVNNQIGF
Sbjct: 419 RAEQFYRGDGEGKKVMSILLHGDAAFCGQGVVFETMHLSDLPDYTTHGTIHIVVNNQIGF 478
Query: 1734 TTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCY 1555
TTDPR SRSSPYCTDV RVV PIFHVN DDPEAVMHVC VAA+WR TF KDVI+D+V Y
Sbjct: 479 TTDPRHSRSSPYCTDVARVVNAPIFHVNGDDPEAVMHVCKVAAEWRATFHKDVIIDIVSY 538
Query: 1554 RRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILED 1375
RR+GHNE+DEPMFTQPLMY++I+ TK AL+ Y +++ EGV + VK KY I E+
Sbjct: 539 RRNGHNEIDEPMFTQPLMYKKIRGTKPALDIYANQLITEGVVTAEEVKSVKDKYEKICEE 598
Query: 1374 AYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEG---F 1204
A+E A+ T+++ +DW+DSPW FF+ +DPLK+ TG +FS P F
Sbjct: 599 AFEQAKIETHIKYKDWIDSPWSGFFEGKDPLKVAPTGVIEETLVHIGNRFSSPPPNAAEF 658
Query: 1203 NLHRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHV 1024
+H+GL R L R++ML++ ++DWA EA+AFGSLLKEGIHVRLSGQDV+RGTFSHRHHV
Sbjct: 659 VIHKGLLRVLAARKEMLENKTIDWALAEAMAFGSLLKEGIHVRLSGQDVERGTFSHRHHV 718
Query: 1023 LHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGD 844
LH Q VD+ Y PL L Q YTVCNSSLSE+ VLGFELGYSM +PN+LV WEAQFGD
Sbjct: 719 LHHQTVDKATYRPLCHLYPDQAPYTVCNSSLSEFGVLGFELGYSMTNPNALVCWEAQFGD 778
Query: 843 FSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEID 664
F+NTAQCIIDQF+SSGQ+KW+RQSGLVMLLPHG EGMGPEHSSAR ERFLQMC++D +
Sbjct: 779 FNNTAQCIIDQFVSSGQAKWVRQSGLVMLLPHGMEGMGPEHSSARVERFLQMCSDDPDYF 838
Query: 663 LEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPM 484
+ F +QLHD NWIVANC+TP N +HLLRRQ+ +PFRKP +V +PKSLLRHP
Sbjct: 839 PPE---SEEFAIRQLHDINWIVANCSTPGNYFHLLRRQIALPFRKPLIVLTPKSLLRHPE 895
Query: 483 ARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVAL 304
RS + G+ F+R+IP+ ++NP VKRV+FCTG+VYYD++ AR+ ++D+A+
Sbjct: 896 CRSNFSEMTDGTEFKRLIPD-ALTAENPNQVKRVIFCTGRVYYDLLKARRDRKLDHDIAI 954
Query: 303 VRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYA 124
R+EQ+SPFPYDLV+ EC KY AE++WAQEEHKN G W++VQPR ++ ++ R Y
Sbjct: 955 SRIEQISPFPYDLVKAECAKYPNAELVWAQEEHKNQGCWTYVQPRFDTAIN-STRDFSYV 1013
Query: 123 GRLPSSSPATGNKFTHMQEQKEMM 52
GR +S ATG+K H++E K ++
Sbjct: 1014 GRPCGASTATGSKAQHLKELKNLL 1037
>gi|31217270|ref|XP_316396.1| ENSANGP00000024901 [Anopheles gambiae]
gi|30176025|gb|EAA44209.1| ENSANGP00000024901 [Anopheles gambiae str.
PEST]
Length = 1018
Score = 1160 bits (3001), Expect = 0.0
Identities = 586/1029 (56%), Positives = 735/1029 (70%), Gaps = 16/1029 (1%)
Frame = -1
Query: 3090 MHRASLICRLASPSRINAI------RNASSGKSHISASTLVQHRNQSVAAAVKHEPFLNG 2929
MHRA + +P + AS + + A++ V+ N + A EPFLNG
Sbjct: 1 MHRARTALHMVNPMGQQNFGSFLLKKQASKLTTELVAASSVKLYNSAAA-----EPFLNG 55
Query: 2928 SSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS-PAA 2752
SSS YI+ MY AWL+DP+SVH SWDAYFRN A LG S PA
Sbjct: 56 SSSNYIDDMYNAWLRDPASVHASWDAYFRNNSYAAPPSLAPVPKNHVPAAQYLGSSLPAV 115
Query: 2751 AQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT-- 2578
A +A R+D I DHL +Q +IRSYQ+RGH +AD+DPLGI +A+++
Sbjct: 116 AGA--GAAVGGRIDDKL----IDDHLAVQAIIRSYQSRGHLVADIDPLGILNAEINPERA 169
Query: 2577 ---IPPELELSFYGLGERDLDREFLLPPTTFISEK-KSLTLREILQRLKDIYCTSTGVEY 2410
++ S+ E D++R F LP TTFI K K L LREIL RL+ YC GVE+
Sbjct: 170 NLRANEKVTRSYMNFEEADMERVFKLPSTTFIGGKEKFLPLREILGRLEKAYCNKIGVEF 229
Query: 2409 MHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEG 2230
M +N+LEQ +WIR RFE P + ++++K+++ RL R+T FE FLAKK+ SEKRFGLEG
Sbjct: 230 MFINSLEQCNWIRERFETPNIMTYTNEEKRLILARLTRATGFEAFLAKKFSSEKRFGLEG 289
Query: 2229 CEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEG 2050
CE++IPAMK+VID S+ LGV+S ++GMPHRGRLNVLANVCR+PL I +QF+ LE AD+G
Sbjct: 290 CEIMIPAMKEVIDVSTRLGVESIIMGMPHRGRLNVLANVCRKPLHQIFTQFAGLEAADDG 349
Query: 2049 SGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRT 1870
SGDVKYHLG IERLNR + KN+++AVVANPSHLEAVDPVV GK RAE FY GD + +
Sbjct: 350 SGDVKYHLGTYIERLNRVTNKNIRLAVVANPSHLEAVDPVVQGKTRAEQFYRGDGEGKKV 409
Query: 1869 MAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTD 1690
M+ILLHGDAAF GQGVV ET +L DLP YTTHG IHIVVNNQIGFTTDPR SRSSPYCTD
Sbjct: 410 MSILLHGDAAFCGQGVVFETMHLSDLPDYTTHGTIHIVVNNQIGFTTDPRHSRSSPYCTD 469
Query: 1689 VGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQ 1510
V RVV PIFHVN DDPEAVMHVC VAA+WR TF KDVI+D+V YRR+GHNE+DEPMFTQ
Sbjct: 470 VARVVNAPIFHVNGDDPEAVMHVCKVAAEWRATFHKDVIIDIVSYRRNGHNEIDEPMFTQ 529
Query: 1509 PLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRD 1330
PLMY++I+ TK AL+ Y +++ EGV + VK KY I E+A+E A+ T+++ +D
Sbjct: 530 PLMYKKIRGTKPALDIYANQLITEGVVTAEEVKSVKDKYEKICEEAFEQAKIETHIKYKD 589
Query: 1329 WLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEG---FNLHRGLERTLKGRQQ 1159
W+DSPW FF+ +DPLK+ TG +FS P F +H+GL R L R++
Sbjct: 590 WIDSPWSGFFEGKDPLKVAPTGVIEETLVHIGNRFSSPPPNAAEFVIHKGLLRVLAARKE 649
Query: 1158 MLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLN 979
ML++ ++DWA EA+AFGSLLKEGIHVRLSGQDV+RGTFSHRHHVLH Q VD+ Y PL
Sbjct: 650 MLENKTIDWALAEAMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHHQTVDKATYRPLC 709
Query: 978 DLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISS 799
L Q YTVCNSSLSE+ VLGFELGYSM +PN+LV WEAQFGDF+NTAQCIIDQF+SS
Sbjct: 710 HLYPDQAPYTVCNSSLSEFGVLGFELGYSMTNPNALVCWEAQFGDFNNTAQCIIDQFVSS 769
Query: 798 GQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQL 619
GQ+KW+RQSGLVMLLPHG EGMGPEHSSAR ERFLQMC++D + + F +QL
Sbjct: 770 GQAKWVRQSGLVMLLPHGMEGMGPEHSSARVERFLQMCSDDPDYFPPE---SEEFAIRQL 826
Query: 618 HDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQ 439
HD NWIVANC+TP N +HLLRRQ+ +PFRKP +V +PKSLLRHP RS + G+ F+
Sbjct: 827 HDINWIVANCSTPGNYFHLLRRQIALPFRKPLIVLTPKSLLRHPECRSNFSEMTDGTEFK 886
Query: 438 RVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQ 259
R+IP+ ++NP VKRV+FCTG+VYYD++ AR+ ++D+A+ R+EQ+SPFPYDLV+
Sbjct: 887 RLIPD-ALTAENPNQVKRVIFCTGRVYYDLLKARRDRKLDHDIAISRIEQISPFPYDLVK 945
Query: 258 QECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFT 79
EC KY AE++WAQEEHKN G W++VQPR ++ ++ R Y GR +S ATG+K
Sbjct: 946 AECAKYPNAELVWAQEEHKNQGCWTYVQPRFDTAIN-STRDFSYVGRPCGASTATGSKAQ 1004
Query: 78 HMQEQKEMM 52
H++E K ++
Sbjct: 1005 HLKELKNLL 1013
>gi|24665669|ref|NP_730223.1| CG11661-PA [Drosophila melanogaster]
gi|24665673|ref|NP_730224.1| CG11661-PB [Drosophila melanogaster]
gi|24665677|ref|NP_730225.1| CG11661-PC [Drosophila melanogaster]
gi|28574592|ref|NP_788519.1| CG11661-PG [Drosophila melanogaster]
gi|28574594|ref|NP_788520.1| CG11661-PH [Drosophila melanogaster]
gi|23093280|gb|AAF49388.2| CG11661-PA [Drosophila melanogaster]
gi|23093281|gb|AAN11722.1| CG11661-PB [Drosophila melanogaster]
gi|23093282|gb|AAF49389.2| CG11661-PC [Drosophila melanogaster]
gi|28380494|gb|AAO41240.1| CG11661-PG [Drosophila melanogaster]
gi|28380495|gb|AAO41241.1| CG11661-PH [Drosophila melanogaster]
gi|28380874|gb|AAO41404.1| SD10782p [Drosophila melanogaster]
Length = 1008
Score = 1156 bits (2990), Expect = 0.0
Identities = 568/1005 (56%), Positives = 724/1005 (71%), Gaps = 11/1005 (1%)
Frame = -1
Query: 3030 NASSGKSHISASTLVQHRNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDA 2851
++S + ++A+ V+ N + A EPF NGS++ Y+E+MY AWL+DP+SVHTSWDA
Sbjct: 28 SSSQQMAKVTAAAAVRTYNSAAA-----EPFANGSTASYVEEMYNAWLRDPTSVHTSWDA 82
Query: 2850 YFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVTTSSAPATRLDTNASV-------Q 2692
YFR+ P A V ++ P T + +V +
Sbjct: 83 YFRSNSYVS--------------------PPNLAPVQANTLPLTAFNFGGAVAGAAPDSK 122
Query: 2691 SISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFL 2512
+I DHL +Q +IRSYQ RGHNIA LDPL IN+ +L + + + GE+D+DR+F
Sbjct: 123 TIDDHLAVQAIIRSYQIRGHNIAHLDPLEINTPELPGNSSTKSIYANFSFGEQDMDRQFK 182
Query: 2511 LPPTTFIS-EKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELS 2335
LP TTFI ++ SL L+EIL RL+++YC GVE+M +N+LEQ +WIR+RFE P V S
Sbjct: 183 LPSTTFIGGDEASLPLKEILNRLENVYCNKIGVEFMFINSLEQCNWIRKRFETPGVLNFS 242
Query: 2334 HDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVI 2155
++K+++ RL R+T FE FLAKK+ SEKRFGLEGCE++IPA+K++ID S+ LGV+S ++
Sbjct: 243 PEEKRLILARLTRATGFEAFLAKKYSSEKRFGLEGCEIMIPALKEIIDVSTELGVESVIM 302
Query: 2154 GMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVKYHLGVCIERLNRQSQKNVKI 1975
GMPHRGRLN LANVCR+PL I +QF+ LE AD+GSGDVKYHLG IERLNR + KN+++
Sbjct: 303 GMPHRGRLNTLANVCRKPLNQIFTQFAGLEAADDGSGDVKYHLGTYIERLNRVTNKNIRL 362
Query: 1974 AVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDD 1795
AVVANPSHLEAVDPVV GK RAE FY GD++ + M+IL+HGDAAF GQGVV ET +L D
Sbjct: 363 AVVANPSHLEAVDPVVQGKTRAEQFYRGDQEGKKVMSILIHGDAAFCGQGVVYETMHLSD 422
Query: 1794 LPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCN 1615
LP YTTHG IH+V NNQIGFTTDPR SRSSPYCTDV RVV PIFHVN DDPEAVMHVC
Sbjct: 423 LPDYTTHGTIHVVANNQIGFTTDPRFSRSSPYCTDVARVVNAPIFHVNADDPEAVMHVCK 482
Query: 1614 VAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEG 1435
VAA+WR TF KD ++DLV YRR+GHNE+DEPMFTQPLMYQ+I++ K L+ Y +K++ EG
Sbjct: 483 VAAEWRATFHKDCVIDLVGYRRNGHNEIDEPMFTQPLMYQKIRKHKNCLDLYADKLIAEG 542
Query: 1434 VANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXX 1255
+ VK KY +I E+A+ A+ T+V+ +DWLDSPW FF+ +DPLK+ TG
Sbjct: 543 TVTAEEVKSVAAKYENICEEAFALAKTETHVKYKDWLDSPWSGFFEGKDPLKVAPTGVKE 602
Query: 1254 XXXXXXIGKFSQYPEG---FNLHRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGI 1084
+FS P F +H+GL R L R+ M+ + DWA GEA+AFGSLLKEGI
Sbjct: 603 ETLIHIGNRFSSPPPNAAEFVIHKGLLRVLAARKAMVDEKVADWALGEAMAFGSLLKEGI 662
Query: 1083 HVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFE 904
HVRLSGQDV+RGTFSHRHHVLH Q VD+ YN L + Q Y+V NSSLSEYAVLGFE
Sbjct: 663 HVRLSGQDVERGTFSHRHHVLHHQLVDKATYNSLQHMYPDQAPYSVSNSSLSEYAVLGFE 722
Query: 903 LGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPE 724
GYSM +PN+LV+WEAQFGDFSNTAQ IIDQFISSGQSKW+RQSGLVMLLPHG EGMGPE
Sbjct: 723 HGYSMTNPNALVLWEAQFGDFSNTAQSIIDQFISSGQSKWVRQSGLVMLLPHGMEGMGPE 782
Query: 723 HSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVT 544
HSS R ERFLQM ++D + + F +QLHD NWIVANC+TPAN YH+LRRQ+
Sbjct: 783 HSSCRVERFLQMSSDDPDYFPPE---SDEFGVRQLHDINWIVANCSTPANYYHILRRQIA 839
Query: 543 MPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGK 364
+PFRKP ++ +PKSLLRHP A+SP + GS FQR+IP+ G QNP +VK+VVFC+G+
Sbjct: 840 LPFRKPLILCTPKSLLRHPEAKSPFSEMSEGSEFQRIIPDNGPAGQNPSNVKKVVFCSGR 899
Query: 363 VYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWS 184
VYYD+ R+ E ++A+VRVEQ+SPFP+DLV+++ Y+ AE++WAQEEHKN G+W+
Sbjct: 900 VYYDLTKTRREKQLEGEIAIVRVEQISPFPFDLVKEQANLYKNAELVWAQEEHKNQGSWT 959
Query: 183 FVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMS 49
+VQPR + L+ R Y GR +S ATG+K H++E +++
Sbjct: 960 YVQPRFLTALN-HSRDVSYVGRACGASTATGSKAQHIRELNALLN 1003
>gi|48097079|ref|XP_391838.1| similar to ENSANGP00000013033 [Apis
mellifera]
Length = 1121
Score = 1155 bits (2987), Expect = 0.0
Identities = 591/1080 (54%), Positives = 730/1080 (66%), Gaps = 106/1080 (9%)
Frame = -1
Query: 2955 VKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAG 2776
V EPFLNGSSS Y+E+MY AWLQDP SVH SWD++FR+ AY
Sbjct: 53 VATEPFLNGSSSSYVEEMYNAWLQDPHSVHVSWDSFFRS--------STAGAAPGLAYQA 104
Query: 2775 ALGVSPAAAQVTTSSAPATRLDTNASV-----QSISDHLKIQLLIRSYQTRGHNIADLDP 2611
++P+ QV + T S + I DHL +Q +IRSYQ RGH +ADLDP
Sbjct: 105 PPSLAPSHNQVPLGALLPLGGSTQLSQIPITEKVIDDHLAVQAIIRSYQARGHLVADLDP 164
Query: 2610 LGI---------------------------------NSADLDDTIPPELELSFYGLGER- 2533
LGI NSADLDD P EL + Y G R
Sbjct: 165 LGIMQTDLIHTHYAARKGSPEQIRGHHIAKLDPLGINSADLDDRHPQELLYNHYSFGNRA 224
Query: 2532 ---------------------DLDREFLLPPTTFISEK-KSLTLREILQRLKDIYCTSTG 2419
D+DR F LP TTFI K KSL LREIL+RL+ YC G
Sbjct: 225 RTTTYSQELQYKIAALTKKESDMDRIFKLPSTTFIGGKEKSLPLREILKRLEAAYCGHIG 284
Query: 2418 VEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFG 2239
VE+M +N+LEQ +WIR++ E P + E+++D+++++ RL R+T FE FLA+KW SEKRFG
Sbjct: 285 VEFMFINSLEQCNWIRQKMETPGIMEMTNDERRLILARLTRATGFEAFLARKWSSEKRFG 344
Query: 2238 LEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPA 2059
LEGCE+LIPAMKQVID S+ LGV+S V+GMPHRGRLNVLANVCR+PL+ I +QF+ LE A
Sbjct: 345 LEGCEILIPAMKQVIDKSTELGVESIVMGMPHRGRLNVLANVCRKPLSQIFTQFAALEAA 404
Query: 2058 DEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKC 1879
D+GSGDVKYHLG IERLNR + KN+++AVVANPSHLEAVDPVV GK RAE FY GD +
Sbjct: 405 DDGSGDVKYHLGTYIERLNRVTNKNIRLAVVANPSHLEAVDPVVQGKTRAEQFYRGDGEG 464
Query: 1878 DRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPY 1699
+ M+ILLHGDAAF GQG+V ET +L DLP YTTHG IHIVVNNQIGFTTDPR SRSSPY
Sbjct: 465 KKVMSILLHGDAAFCGQGIVFETMHLSDLPDYTTHGTIHIVVNNQIGFTTDPRHSRSSPY 524
Query: 1698 CTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPM 1519
CTDV RVV PIFHVN DDPEAVMHVC VAA+WR TF KDV++D+V YRR+GHNE+DEPM
Sbjct: 525 CTDVARVVNAPIFHVNSDDPEAVMHVCKVAAEWRATFHKDVVIDIVSYRRNGHNEIDEPM 584
Query: 1518 FTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVR 1339
FTQPLMY++IK T L+KY + + ++GV + VK+ KY I E+AY NA++ T+++
Sbjct: 585 FTQPLMYRKIKNTPPVLDKYAKTLTDDGVVTSEEVKDVKDKYEKICEEAYVNAKQETHIK 644
Query: 1338 NRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEG---FNLHRGLERTLKG 1168
+DWLDSPW FF+ +DPLK+ TG KFS P F +H+G+ER LK
Sbjct: 645 YKDWLDSPWSGFFEGKDPLKVSPTGIKEDTLIHIGKKFSSPPPNAAEFVVHKGIERILKS 704
Query: 1167 RQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYN 988
R +M++ ++DWA GEA+AFGSLLKEGIHVRLSGQDV+RGTFSHRHHVLH Q VD+ Y
Sbjct: 705 RMEMIEARTVDWALGEAMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHHQTVDKATYR 764
Query: 987 PLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQF 808
PL L Q YTVCNSSLSE+ VLGFELGYSM +PN+LV WEAQFGDF+NTAQCIIDQF
Sbjct: 765 PLCYLYPDQAPYTVCNSSLSEFGVLGFELGYSMTNPNALVCWEAQFGDFNNTAQCIIDQF 824
Query: 807 ISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEA 628
ISSGQ+KW+RQSGLVML PHG EGMGPEHSSAR ERFLQM +D + + F
Sbjct: 825 ISSGQAKWVRQSGLVMLQPHGLEGMGPEHSSARLERFLQMSADDPDYFPPE---NEEFAV 881
Query: 627 QQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGS 448
+QLHD NWIVANC+TPAN +H+LRRQ+ +PFRKP ++ +PKSLLRHP A+S + +
Sbjct: 882 RQLHDINWIVANCSTPANYFHILRRQIALPFRKPLILMTPKSLLRHPEAKSNFDLMLENT 941
Query: 447 NFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYD 268
F RVIPE G SQNP +VKRV+FC+GK+YYD+ AR ++ VA++R+EQ+SPFPYD
Sbjct: 942 EFLRVIPEEGVASQNPNNVKRVLFCSGKIYYDLKKARAEKNLDDKVAIIRIEQISPFPYD 1001
Query: 267 LVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLL-----------SIDG------- 142
LV++E KY A+++WAQEEHKN GAW+++QPR ++ L S D
Sbjct: 1002 LVKKEAVKYSNADLVWAQEEHKNQGAWTYIQPRFHTALNGTRSVSSGNTSYDSKDSRGWF 1061
Query: 141 ------------------------RATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGV 34
R +Y GR +SPATG+K H++E K+++ F +
Sbjct: 1062 SGWFSTKPTIVSEPLSKESNKSKQRTLRYVGRPTGASPATGSKMQHLKELKQLLDDSFNL 1121
>gi|13436359|gb|AAH04964.1| OGDH protein [Homo sapiens]
gi|15779103|gb|AAH14617.1| OGDH protein [Homo sapiens]
gi|37674435|gb|AAQ96885.1| unknown [Homo sapiens]
Length = 1023
Score = 1145 bits (2962), Expect = 0.0
Identities = 560/988 (56%), Positives = 717/988 (71%), Gaps = 13/988 (1%)
Frame = -1
Query: 2964 AAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXA 2785
+A V EPFL+G+SS Y+E+MY AWL++P SVH SWD +FRN
Sbjct: 41 SAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNAGAPPGTA-------- 92
Query: 2784 YAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLG 2605
Y L +S + + N + + DHL +Q LIR+YQ RGH++A LDPLG
Sbjct: 93 YQSPLPLSRGSLAAVAHAQSLVEAQPNVD-KLVEDHLAVQSLIRAYQIRGHHVAQLDPLG 151
Query: 2604 INSADLDDTIPPEL-----ELSFYGLGERDLDREFLLPPTTFISEKKS-LTLREILQRLK 2443
I ADLD ++P ++ +L FYGL E DLD+ F LP TTFI ++S L LREI++RL+
Sbjct: 152 ILDADLDSSVPADIISSTDKLGFYGLDESDLDKVFHLPTTTFIGGQESALPLREIIRRLE 211
Query: 2442 DIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKK 2263
YC GVE+M +N+LEQ WIR++FE P + + ++++K+ L RL+RST+FEEFL +K
Sbjct: 212 MAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRK 271
Query: 2262 WPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILS 2083
W SEKRFGLEGCEVLIPA+K +ID SS GVD ++GMPHRGRLNVLANV R+ L I
Sbjct: 272 WSSEKRFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFC 331
Query: 2082 QF-STLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAE 1906
QF S LE ADEGSGDVKYHLG+ R+NR + +N+ +++VANPSHLEA DPVVMGK +AE
Sbjct: 332 QFDSKLEAADEGSGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAE 391
Query: 1905 AFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTD 1726
FY GD + + M+ILLHGDAAFAGQG+V ETF+L DLPSYTTHG +H+VVNNQIGFTTD
Sbjct: 392 QFYCGDTEGKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTD 451
Query: 1725 PRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRH 1546
PR +RSSPY TDV RVV PIFHVN DDPEAVM+VC VAA+WR TF KDV+VDLVCYRR+
Sbjct: 452 PRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCYRRN 511
Query: 1545 GHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYE 1366
GHNE+DEPMFTQPLMY++I++ K L+KY E ++++GV N+ +EE++KY I E+A+
Sbjct: 512 GHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFA 571
Query: 1365 NAQKVTYVRNRDWLDSPWDDFFK---KRDPLKLPSTGXXXXXXXXXIGKFSQYP-EGFNL 1198
++ + + WLDSPW FF + + PSTG S P E F +
Sbjct: 572 RSKDEKILHIKHWLDSPWPGFFTLDGQPRSMSCPSTGLTEDILTHIGNVASSVPVENFTI 631
Query: 1197 HRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLH 1018
H GL R LK R +M+K+ ++DWA E +AFGSLLKEGIH+RLSGQDV+RGTFSHRHHVLH
Sbjct: 632 HGGLSRILKTRGEMVKNRTVDWALAEYMAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLH 691
Query: 1017 DQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFS 838
DQ VD++ P+N L Q YTVCNSSLSEY VLGFELG++M PN+LV+WEAQFGDF
Sbjct: 692 DQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFH 751
Query: 837 NTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI--D 664
NTAQCIIDQFI GQ+KW+RQ+G+V+LLPHG EGMGPEHSSARPERFLQMCN+D ++ D
Sbjct: 752 NTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPD 811
Query: 663 LEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPM 484
L+ E F+ QL+D NW+V NC+TP N +H+LRRQ+ +PFRKP ++F+PKSLLRHP
Sbjct: 812 LK----EANFDINQLYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPE 867
Query: 483 ARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVAL 304
ARS ++ G++FQRVIPE G +QNP +VKR++FCTGKVYYD+ RK VA+
Sbjct: 868 ARSSFDEMLPGTHFQRVIPEDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAI 927
Query: 303 VRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYA 124
R+EQLSPFP+DL+ +E +KY AE+ W QEEHKN G + +V+PR+ + +S + YA
Sbjct: 928 TRIEQLSPFPFDLLLKEVQKYPNAELAWCQEEHKNQGYYDYVKPRLRTTIS-RAKPVWYA 986
Query: 123 GRLPSSSPATGNKFTHMQEQKEMMSKVF 40
GR P+++PATGNK TH+ E + ++ F
Sbjct: 987 GRDPAAAPATGNKKTHLTELQRLLDTAF 1014
>gi|28574590|ref|NP_788518.1| CG11661-PF [Drosophila melanogaster]
gi|23093279|gb|AAN11721.1| CG11661-PF [Drosophila melanogaster]
gi|46409160|gb|AAS93737.1| RE42354p [Drosophila melanogaster]
Length = 1017
Score = 1142 bits (2955), Expect = 0.0
Identities = 567/1017 (55%), Positives = 724/1017 (70%), Gaps = 23/1017 (2%)
Frame = -1
Query: 3030 NASSGKSHISASTLVQHRNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDA 2851
++S + ++A+ V+ N + A EPF NGS++ Y+E+MY AWL+DP+SVHTSWDA
Sbjct: 28 SSSQQMAKVTAAAAVRTYNSAAA-----EPFANGSTASYVEEMYNAWLRDPTSVHTSWDA 82
Query: 2850 YFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVTTSSAPATRLDTNASV-------Q 2692
YFR+ P A V ++ P T + +V +
Sbjct: 83 YFRSNSYVS--------------------PPNLAPVQANTLPLTAFNFGGAVAGAAPDSK 122
Query: 2691 SISDHLKIQLLIRSYQTRGHNIADLDPLGINSADL------------DDTIPPELELSFY 2548
+I DHL +Q +IRSYQ+RGH +DLDPLGI + + +D + F
Sbjct: 123 TIDDHLAVQAIIRSYQSRGHLASDLDPLGILTREKTVCKDGLARRANEDVLRQHSGFLF- 181
Query: 2547 GLGERDLDREFLLPPTTFIS-EKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIR 2371
GE+D+DR+F LP TTFI ++ SL L+EIL RL+++YC GVE+M +N+LEQ +WIR
Sbjct: 182 --GEQDMDRQFKLPSTTFIGGDEASLPLKEILNRLENVYCNKIGVEFMFINSLEQCNWIR 239
Query: 2370 RRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVID 2191
+RFE P V S ++K+++ RL R+T FE FLAKK+ SEKRFGLEGCE++IPA+K++ID
Sbjct: 240 KRFETPGVLNFSPEEKRLILARLTRATGFEAFLAKKYSSEKRFGLEGCEIMIPALKEIID 299
Query: 2190 SSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVKYHLGVCIE 2011
S+ LGV+S ++GMPHRGRLN LANVCR+PL I +QF+ LE AD+GSGDVKYHLG IE
Sbjct: 300 VSTELGVESVIMGMPHRGRLNTLANVCRKPLNQIFTQFAGLEAADDGSGDVKYHLGTYIE 359
Query: 2010 RLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAG 1831
RLNR + KN+++AVVANPSHLEAVDPVV GK RAE FY GD++ + M+IL+HGDAAF G
Sbjct: 360 RLNRVTNKNIRLAVVANPSHLEAVDPVVQGKTRAEQFYRGDQEGKKVMSILIHGDAAFCG 419
Query: 1830 QGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVN 1651
QGVV ET +L DLP YTTHG IH+V NNQIGFTTDPR SRSSPYCTDV RVV PIFHVN
Sbjct: 420 QGVVYETMHLSDLPDYTTHGTIHVVANNQIGFTTDPRFSRSSPYCTDVARVVNAPIFHVN 479
Query: 1650 VDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTA 1471
DDPEAVMHVC VAA+WR TF KD ++DLV YRR+GHNE+DEPMFTQPLMYQ+I++ K
Sbjct: 480 ADDPEAVMHVCKVAAEWRATFHKDCVIDLVGYRRNGHNEIDEPMFTQPLMYQKIRKHKNC 539
Query: 1470 LEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKR 1291
L+ Y +K++ EG + VK KY +I E+A+ A+ T+V+ +DWLDSPW FF+ +
Sbjct: 540 LDLYADKLIAEGTVTAEEVKSVAAKYENICEEAFALAKTETHVKYKDWLDSPWSGFFEGK 599
Query: 1290 DPLKLPSTGXXXXXXXXXIGKFSQYPEG---FNLHRGLERTLKGRQQMLKDNSLDWACGE 1120
DPLK+ TG +FS P F +H+GL R L R+ M+ + DWA GE
Sbjct: 600 DPLKVAPTGVKEETLIHIGNRFSSPPPNAAEFVIHKGLLRVLAARKAMVDEKVADWALGE 659
Query: 1119 ALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCN 940
A+AFGSLLKEGIHVRLSGQDV+RGTFSHRHHVLH Q VD+ YN L + Q Y+V N
Sbjct: 660 AMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHHQLVDKATYNSLQHMYPDQAPYSVSN 719
Query: 939 SSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVM 760
SSLSEYAVLGFE GYSM +PN+LV+WEAQFGDFSNTAQ IIDQFISSGQSKW+RQSGLVM
Sbjct: 720 SSLSEYAVLGFEHGYSMTNPNALVLWEAQFGDFSNTAQSIIDQFISSGQSKWVRQSGLVM 779
Query: 759 LLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTP 580
LLPHG EGMGPEHSS R ERFLQM ++D + + F +QLHD NWIVANC+TP
Sbjct: 780 LLPHGMEGMGPEHSSCRVERFLQMSSDDPDYFPPE---SDEFGVRQLHDINWIVANCSTP 836
Query: 579 ANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNP 400
AN YH+LRRQ+ +PFRKP ++ +PKSLLRHP A+SP + GS FQR+IP+ G QNP
Sbjct: 837 ANYYHILRRQIALPFRKPLILCTPKSLLRHPEAKSPFSEMSEGSEFQRIIPDNGPAGQNP 896
Query: 399 PDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILW 220
+VK+VVFC+G+VYYD+ R+ E ++A+VRVEQ+SPFP+DLV+++ Y+ AE++W
Sbjct: 897 SNVKKVVFCSGRVYYDLTKTRREKQLEGEIAIVRVEQISPFPFDLVKEQANLYKNAELVW 956
Query: 219 AQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMS 49
AQEEHKN G+W++VQPR + L+ R Y GR +S ATG+K H++E +++
Sbjct: 957 AQEEHKNQGSWTYVQPRFLTALN-HSRDVSYVGRACGASTATGSKAQHIRELNALLN 1012
>gi|49118217|gb|AAH73213.1| Unknown (protein for MGC:80496) [Xenopus
laevis]
Length = 1018
Score = 1142 bits (2953), Expect = 0.0
Identities = 555/991 (56%), Positives = 716/991 (72%), Gaps = 9/991 (0%)
Frame = -1
Query: 2967 VAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXX 2788
++ V EPFL+G+SS Y+E+MY AWL++P SVH SWD +FRN
Sbjct: 40 LSTPVAAEPFLSGTSSNYVEEMYYAWLENPKSVHKSWDIFFRNANAGASPG--------- 90
Query: 2787 AYAGALGVSPAAAQVTTSSAPATRLDTNASVQS-ISDHLKIQLLIRSYQTRGHNIADLDP 2611
A P + ++T S + + ++ + DHL +Q LIR+YQ RGH+IA LDP
Sbjct: 91 --AAYQSPPPLGSSLSTLSQAQSLVQARPNIDKLVGDHLAVQSLIRAYQVRGHHIAKLDP 148
Query: 2610 LGINSADLDDT--IPPELELSFYGLGERDLDREFLLPPTTFI-SEKKSLTLREILQRLKD 2440
LGI+S + D I + FYGL E DLD+ F LP TTFI S + +L LREI++RL+
Sbjct: 149 LGISSVNFDGAPVIVGSPNVGFYGLEESDLDKVFHLPTTTFIGSNEMALPLREIIRRLES 208
Query: 2439 IYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKW 2260
YC GVE+M +N+LEQ WIR++FE P + + + ++K+ L RL+RST+FEEFL +KW
Sbjct: 209 AYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFNSEEKRTLLARLVRSTRFEEFLHRKW 268
Query: 2259 PSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQ 2080
SEKRFGLEGCEVLIPA+K +ID SS GVD ++GMPHRGRLNVLANV R+ L I Q
Sbjct: 269 SSEKRFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQ 328
Query: 2079 F-STLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEA 1903
F S LE DEGSGDVKYHLG+ R+NR + +N+ ++++ANPSHLEA DPVV GK +AE
Sbjct: 329 FDSKLEATDEGSGDVKYHLGMYHRRINRVTDRNITLSLMANPSHLEAADPVVQGKTKAEQ 388
Query: 1902 FYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDP 1723
FY GD + + M+ILLHGDAAFAGQG+V ETF+L DLPSYTTHG +H+VVNNQIGFTTDP
Sbjct: 389 FYCGDTEGKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDP 448
Query: 1722 RSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHG 1543
R +RSSPY TDV RVV PIFHVN DDPEAVM+VCNVAA+WR TF KDV+VDLVCYRR+G
Sbjct: 449 RMARSSPYPTDVARVVNAPIFHVNADDPEAVMYVCNVAAEWRSTFHKDVVVDLVCYRRNG 508
Query: 1542 HNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYEN 1363
HNE+DEPMFTQPLMY++I++ KT L+KY E ++++GV N+ +EE++KY I E+A+
Sbjct: 509 HNEMDEPMFTQPLMYKQIRKQKTVLQKYAETLVSQGVVNQSEYEEEISKYDKICEEAFAR 568
Query: 1362 AQKVTYVRNRDWLDSPWDDFFK---KRDPLKLPSTGXXXXXXXXXIGKFSQYP-EGFNLH 1195
++ + + WLDSPW FF + + PSTG S P E F +H
Sbjct: 569 SKDEKILHIKHWLDSPWPGFFTLDGQPRSMTCPSTGLSEEELTHIGNVASSVPVEDFTIH 628
Query: 1194 RGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHD 1015
GL R LKGR +M+K+ ++DWA E ++ GSLLKEGIH+RLSGQDV+RGTFSHRHHVLHD
Sbjct: 629 GGLSRILKGRGEMVKNRTVDWALAEYMSLGSLLKEGIHIRLSGQDVERGTFSHRHHVLHD 688
Query: 1014 QKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSN 835
Q VD++ P+N L Q YTVCNSSLSEY VLGFELG++M PN+LV+WEAQFGDF N
Sbjct: 689 QNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHN 748
Query: 834 TAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEK 655
TAQCIIDQF+ GQ+KW+RQ+G+V+LLPHG EGMGPEHSSARPERFLQMCN+D ++ +
Sbjct: 749 TAQCIIDQFVCPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDSDVWPKA 808
Query: 654 IAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARS 475
F +QL+D NWIV NC+TPAN +H++RRQ+ +PFRKP +VF+PKSLLRHP ARS
Sbjct: 809 ---SEDFAVRQLYDCNWIVVNCSTPANFFHVIRRQILLPFRKPLIVFTPKSLLRHPEARS 865
Query: 474 PVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRV 295
+D +G++F+R+IP+ G SQNP VKR++FC GKVYYD+ R G E DVA+ RV
Sbjct: 866 SFDDMLAGTHFERIIPDAGPASQNPEGVKRLIFCAGKVYYDLTKERSGRGMEGDVAITRV 925
Query: 294 EQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRL 115
EQLSPFP+DLV++E +KY A+++W QEEHKN G + +V+PR+ + + + YAGR
Sbjct: 926 EQLSPFPFDLVEKEVQKYPNADLVWCQEEHKNQGYYDYVKPRLRTTIH-RAKPVWYAGRD 984
Query: 114 PSSSPATGNKFTHMQEQKEMMSKVFGVPKSK 22
P+++PATGNK TH+ E K ++ F + K
Sbjct: 985 PAAAPATGNKKTHLTELKRLLDTSFNLDSFK 1015
>gi|38303923|gb|AAH61938.1| MGC68800 protein [Xenopus laevis]
Length = 1021
Score = 1141 bits (2952), Expect = 0.0
Identities = 563/1022 (55%), Positives = 731/1022 (71%), Gaps = 14/1022 (1%)
Frame = -1
Query: 3045 INAIRNASSGKSHISASTLVQHRNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVH 2866
+ A + S K + A+ + + ++ V EPFL+G++S Y+E+MY AWL++P SVH
Sbjct: 14 LTASQTIRSLKHNRPAAPRTFQQFRCLSTPVAAEPFLSGTNSNYVEEMYYAWLENPKSVH 73
Query: 2865 TSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAA--AQVTTSSAPATRLDTNASVQ 2692
SWD +FRN GA SP + + ++T + + L + +V
Sbjct: 74 KSWDIFFRNANAGAS-------------PGAAYQSPPSLGSSLSTLTQAQSLLHSQPNVD 120
Query: 2691 S-ISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPEL-----ELSFYGLGERD 2530
+ DHL +Q LIR+YQ RGH++A LDPLGI ADLD +P ++ +L FYGL E D
Sbjct: 121 KLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSCVPADIVTSSDKLGFYGLQESD 180
Query: 2529 LDREFLLPPTTFIS-EKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAP 2353
LD+ F LP TTFI + +L LREI++RL++ YC GVE+M +N+LEQ WIR++FEAP
Sbjct: 181 LDKVFHLPTTTFIGGNEMALPLREIIRRLENAYCQHIGVEFMFINDLEQCQWIRQKFEAP 240
Query: 2352 RVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLG 2173
+ + ++++K+ L RL+RST+FEEFL +KW SEKRFGLEGCEVLIPA+K +ID SS G
Sbjct: 241 GIMQFNNEEKRTLLARLVRSTRFEEFLHRKWSSEKRFGLEGCEVLIPALKTIIDKSSGNG 300
Query: 2172 VDSFVIGMPHRGRLNVLANVCRQPLATILSQF-STLEPADEGSGDVKYHLGVCIERLNRQ 1996
VD ++GMPHRGRLNVLANV R+ L I QF S LE DEGSGDVKYHLG+ R+NR
Sbjct: 301 VDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEATDEGSGDVKYHLGMYHRRINRV 360
Query: 1995 SQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVL 1816
+ +N+ +++VANPSHLEA DPVV GK +AE FY GD + + MAILLHGDAAFAGQG+V
Sbjct: 361 TDRNITLSLVANPSHLEAADPVVQGKTKAEQFYCGDTEGKKVMAILLHGDAAFAGQGIVY 420
Query: 1815 ETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPE 1636
ETF+L DLPS+TTHG +H+VVNNQIGFTTDPR +RSSPY TDV RVV PIFHVN DDPE
Sbjct: 421 ETFHLSDLPSHTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPE 480
Query: 1635 AVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQ 1456
AVM+VCNVAA+WR TF KDV+VDLVCYRR+GHNE+DEPMFTQPLMY++I++ K L+KY
Sbjct: 481 AVMYVCNVAAEWRSTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKAVLQKYA 540
Query: 1455 EKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFK---KRDP 1285
E ++++GV N+ +EE++KY I E+A+ ++ + + WLDSPW FF +
Sbjct: 541 ETLISQGVVNQLEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFTLDGQPRS 600
Query: 1284 LKLPSTGXXXXXXXXXIGKFSQYP-EGFNLHRGLERTLKGRQQMLKDNSLDWACGEALAF 1108
+ PSTG S P E F +H GL R LKGR +M+K+ ++DWA E +A
Sbjct: 601 MTCPSTGLTEEDLTHIGNVASSVPVEDFMIHGGLSRILKGRGEMVKNRTVDWALAEYMAL 660
Query: 1107 GSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLS 928
GSLLKEGIH+RLSGQDV+RGTFSHRHHVLHDQ VD++ P+N L Q YTVCNSSLS
Sbjct: 661 GSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLS 720
Query: 927 EYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPH 748
EY VLGFELG++M PN+LV+WEAQFGDF NTAQCIIDQF+ GQ+KW+RQ+G+V+LLPH
Sbjct: 721 EYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFVCPGQAKWVRQNGIVLLLPH 780
Query: 747 GYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIY 568
G EGMGPEHSSARPERFLQMCN+D ++ + F QL+D NWIV NC+TPAN +
Sbjct: 781 GMEGMGPEHSSARPERFLQMCNDDPDVWPKA---SEDFAVGQLYDCNWIVVNCSTPANFF 837
Query: 567 HLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVK 388
H++RRQ+ +PFRKP +VF+PKSLLRHP ARS +D ++FQR+IPE G SQNP VK
Sbjct: 838 HVIRRQILLPFRKPLIVFTPKSLLRHPEARSSFDDMLPSTHFQRIIPEAGPASQNPEGVK 897
Query: 387 RVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEE 208
R++FCTGKVYY++ R E DVA+ RVEQLSPFP+DLV++E +KY A+++W QEE
Sbjct: 898 RLIFCTGKVYYELTKERSGRDMEGDVAIARVEQLSPFPFDLVEKEVQKYPNADLVWCQEE 957
Query: 207 HKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGVPK 28
HKN G + +V+PR+ + + + YAGR P+++PATGNK TH+ E + + F +
Sbjct: 958 HKNQGYYDYVKPRLRTTIH-RTKPVWYAGRDPAAAPATGNKKTHLTELRRFLDTAFNLDA 1016
Query: 27 SK 22
K
Sbjct: 1017 FK 1018
>gi|49115318|gb|AAH73298.1| MGC68800 protein [Xenopus laevis]
Length = 1021
Score = 1141 bits (2951), Expect = 0.0
Identities = 563/1022 (55%), Positives = 730/1022 (71%), Gaps = 14/1022 (1%)
Frame = -1
Query: 3045 INAIRNASSGKSHISASTLVQHRNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVH 2866
+ A + S K + A+ + + ++ V EPFL+G++S Y+E+MY AWL++P SVH
Sbjct: 14 LTASQTIRSLKHNRPAAPRTFQQFRCLSTPVAAEPFLSGTNSNYVEEMYYAWLENPKSVH 73
Query: 2865 TSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAA--AQVTTSSAPATRLDTNASVQ 2692
SWD +FRN GA SP + + ++T + + L +V
Sbjct: 74 KSWDIFFRNANAGAS-------------PGAAYQSPPSLGSSLSTLTQAQSLLHAQPNVD 120
Query: 2691 S-ISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPEL-----ELSFYGLGERD 2530
+ DHL +Q LIR+YQ RGH++A LDPLGI ADLD +P ++ +L FYGL E D
Sbjct: 121 KLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSCVPADIVTSSDKLGFYGLQESD 180
Query: 2529 LDREFLLPPTTFIS-EKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAP 2353
LD+ F LP TTFI + +L LREI++RL++ YC GVE+M +N+LEQ WIR++FEAP
Sbjct: 181 LDKVFHLPTTTFIGGNEMALPLREIIRRLENAYCQHIGVEFMFINDLEQCQWIRQKFEAP 240
Query: 2352 RVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLG 2173
+ + ++++K+ L RL+RST+FEEFL +KW SEKRFGLEGCEVLIPA+K +ID SS G
Sbjct: 241 GIMQFNNEEKRTLLARLVRSTRFEEFLHRKWSSEKRFGLEGCEVLIPALKTIIDKSSGNG 300
Query: 2172 VDSFVIGMPHRGRLNVLANVCRQPLATILSQF-STLEPADEGSGDVKYHLGVCIERLNRQ 1996
VD ++GMPHRGRLNVLANV R+ L I QF S LE DEGSGDVKYHLG+ R+NR
Sbjct: 301 VDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEATDEGSGDVKYHLGMYHRRINRV 360
Query: 1995 SQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVL 1816
+ +N+ +++VANPSHLEA DPVV GK +AE FY GD + + MAILLHGDAAFAGQG+V
Sbjct: 361 TDRNITLSLVANPSHLEAADPVVQGKTKAEQFYCGDTEGKKVMAILLHGDAAFAGQGIVY 420
Query: 1815 ETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPE 1636
ETF+L DLPS+TTHG +H+VVNNQIGFTTDPR +RSSPY TDV RVV PIFHVN DDPE
Sbjct: 421 ETFHLSDLPSHTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPE 480
Query: 1635 AVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQ 1456
AVM+VCNVAA+WR TF KDV+VDLVCYRR+GHNE+DEPMFTQPLMY++I++ K L+KY
Sbjct: 481 AVMYVCNVAAEWRSTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKAVLQKYA 540
Query: 1455 EKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFK---KRDP 1285
E ++++GV N+ +EE++KY I E+A+ ++ + + WLDSPW FF +
Sbjct: 541 ETLISQGVVNQLEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFTLDGQPRS 600
Query: 1284 LKLPSTGXXXXXXXXXIGKFSQYP-EGFNLHRGLERTLKGRQQMLKDNSLDWACGEALAF 1108
+ PSTG S P E F +H GL R LKGR +M+K+ ++DWA E +A
Sbjct: 601 MTCPSTGLTEEDLTHIGNVASSVPVEDFMIHGGLSRILKGRGEMVKNRTVDWALAEYMAL 660
Query: 1107 GSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLS 928
GSLLKEGIH+RLSGQDV+RGTFSHRHHVLHDQ VD++ P+N L Q YTVCNSSLS
Sbjct: 661 GSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLS 720
Query: 927 EYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPH 748
EY VLGFELG++M PN+LV+WEAQFGDF NTAQCIIDQF+ GQ+KW+RQ+G+V+LLPH
Sbjct: 721 EYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFVCPGQAKWVRQNGIVLLLPH 780
Query: 747 GYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIY 568
G EGMGPEHSSARPERFLQMCN+D ++ + F QL+D NWIV NC+TPAN +
Sbjct: 781 GMEGMGPEHSSARPERFLQMCNDDPDVWPKA---SEDFAVGQLYDCNWIVVNCSTPANFF 837
Query: 567 HLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVK 388
H++RRQ+ +PFRKP +VF+PKSLLRHP ARS +D ++FQR+IPE G SQNP VK
Sbjct: 838 HVIRRQILLPFRKPLIVFTPKSLLRHPEARSSFDDMLPSTHFQRIIPEAGPASQNPEGVK 897
Query: 387 RVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEE 208
R++FCTGKVYY++ R E DVA+ RVEQLSPFP+DLV++E +KY A+++W QEE
Sbjct: 898 RLIFCTGKVYYELTKERSGRDMEGDVAIARVEQLSPFPFDLVEKEVQKYPNADLVWCQEE 957
Query: 207 HKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGVPK 28
HKN G + +V+PR+ + + + YAGR P+++PATGNK TH+ E + + F +
Sbjct: 958 HKNQGYYDYVKPRLRTTIH-RTKPVWYAGRDPAAAPATGNKKTHLTELRRFLDTAFNLDA 1016
Query: 27 SK 22
K
Sbjct: 1017 FK 1018
>gi|15489120|gb|AAH13670.1| Ogdh protein [Mus musculus]
Length = 1023
Score = 1138 bits (2944), Expect = 0.0
Identities = 562/1005 (55%), Positives = 721/1005 (70%), Gaps = 24/1005 (2%)
Frame = -1
Query: 2964 AAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXA 2785
+A V EPFL+G+SS Y+E+MY AWL++P SVH SWD +FRN
Sbjct: 41 SAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNA--------------- 85
Query: 2784 YAGALGVSPAAAQVTTSSAPATRLDTNASVQS-----------ISDHLKIQLLIRSYQTR 2638
G P A + S + L T A QS + DHL +Q LIR+YQ R
Sbjct: 86 -----GAPPGTAYQSPLSLSRSSLATMAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIR 140
Query: 2637 GHNIADLDPLGINSADLDDTIPPEL-----ELSFYGLGERDLDREFLLPPTTFIS-EKKS 2476
GH++A LDPLGI ADLD ++P ++ +L FYGL E DLD+ F LP TTFI ++ +
Sbjct: 141 GHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLHESDLDKVFHLPTTTFIGGQEPA 200
Query: 2475 LTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIR 2296
L LREI++RL+ YC GVE+M +N+LEQ WIR++FE P + + ++++K+ L RL+R
Sbjct: 201 LPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVR 260
Query: 2295 STKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLAN 2116
ST+FEEFL +KW SEKRFGLEGCEVLIPA+K +ID SS GVD ++GMPHRGRLNVLAN
Sbjct: 261 STRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDMSSANGVDYVIMGMPHRGRLNVLAN 320
Query: 2115 VCRQPLATILSQF-STLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAV 1939
V R+ L I QF S LE ADEGSGD+KYHLG+ R+NR + +N+ +++VANPSHLEA
Sbjct: 321 VIRKELEQIFCQFDSKLEAADEGSGDMKYHLGMYHRRINRVTDRNITLSLVANPSHLEAA 380
Query: 1938 DPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHI 1759
DPVVMGK +AE FY GD + + M+ILLHGDAAFAGQG+V ETF+L DLPSYTTHG +H+
Sbjct: 381 DPVVMGKTKAEQFYCGDTEGKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHV 440
Query: 1758 VVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKD 1579
VVNNQIGFTTDPR +RSSPY TDV RVV PIFHVN DDPEAVM+VC VAA+WR TF KD
Sbjct: 441 VVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRNTFHKD 500
Query: 1578 VIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELT 1399
V+VDLVCYRR+GHNE+DEPMFTQPLMY++I++ K L+KY E ++++GV N+ +EE++
Sbjct: 501 VVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEIS 560
Query: 1398 KYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFK---KRDPLKLPSTGXXXXXXXXXIGK 1228
KY I E+A+ ++ + + WLDSPW FF + + PSTG
Sbjct: 561 KYDKICEEAFTRSKDEKILHIKHWLDSPWPGFFTLDGQPRSMTCPSTGLEEDVLFHIGKV 620
Query: 1227 FSQYP-EGFNLHRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQR 1051
S P E F +H GL R LK R++++ + ++DWA E +AFGSLLKEGIHVRLSGQDV+R
Sbjct: 621 ASSVPVENFTIHGGLSRILKTRRELVTNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVER 680
Query: 1050 GTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSL 871
GTFSHRHHVLHDQ VD++ P+N L Q YTVCNSSLSEY VLGFELG++M PN+L
Sbjct: 681 GTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNAL 740
Query: 870 VIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQ 691
V+WEAQFGDF+N AQCIIDQFI GQ+KW+RQ+G+V+LLPHG EGMGPEHSSARPERFLQ
Sbjct: 741 VLWEAQFGDFNNMAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQ 800
Query: 690 MCNEDDEI--DLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVV 517
MCN+D ++ DL+ E F+ QL+D NWIV NC+TP N +H+LRRQ+ +PFRKP +V
Sbjct: 801 MCNDDPDVLPDLQ----EENFDINQLYDCNWIVVNCSTPGNFFHVLRRQILLPFRKPLIV 856
Query: 516 FSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAAR 337
F+PKSLLRHP AR+ ++ G++FQRVIPE G +Q+P VKR++FCTGKVYYD+ R
Sbjct: 857 FTPKSLLRHPEARTSFDEMLPGTHFQRVIPENGPAAQDPHKVKRLLFCTGKVYYDLTRER 916
Query: 336 KHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSL 157
K E +VA+ R+EQLSPFP+DL+ +E +KY AE+ W QEEHKN G + +V+PR+ +
Sbjct: 917 KARNMEEEVAITRIEQLSPFPFDLLLKEAQKYPNAELAWCQEEHKNQGYYDYVKPRLRTT 976
Query: 156 LSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGVPKSK 22
+ + YAGR P+++PATGNK TH+ E + + F + K
Sbjct: 977 ID-RAKPVWYAGRDPAAAPATGNKKTHLTELQRFLDTAFDLDAFK 1020
>gi|4505493|ref|NP_002532.1| oxoglutarate (alpha-ketoglutarate)
dehydrogenase (lipoamide); oxoglutarate dehydrogenase
(lipoamide) [Homo sapiens]
gi|1352618|sp|Q02218|ODO1_HUMAN 2-oxoglutarate dehydrogenase E1
component, mitochondrial precursor (Alpha-ketoglutarate
dehydrogenase)
gi|531241|dbj|BAA01393.1| 2-oxoglutarate dehydrogenase precursor
[Homo sapiens]
Length = 1002
Score = 1136 bits (2938), Expect = 0.0
Identities = 557/976 (57%), Positives = 708/976 (72%), Gaps = 13/976 (1%)
Frame = -1
Query: 2964 AAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXA 2785
+A V EPFL+G+SS Y+E+MY AWL++P SVH SWD +FRN
Sbjct: 41 SAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNAGAPPGTA-------- 92
Query: 2784 YAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLG 2605
Y L +S + + N + + DHL +Q LIR+YQ RGH++A LDPLG
Sbjct: 93 YQSPLPLSRGSLAAVAHAQSLVEAQPNVD-KLVEDHLAVQSLIRAYQIRGHHVAQLDPLG 151
Query: 2604 INSADLDDTIPPEL-----ELSFYGLGERDLDREFLLPPTTFISEKKS-LTLREILQRLK 2443
I ADLD ++P ++ +L FYGL E DLD+ F LP TTFI ++S L LREI++RL+
Sbjct: 152 ILDADLDSSVPADIISSTDKLGFYGLDESDLDKVFHLPTTTFIGGQESALPLREIIRRLE 211
Query: 2442 DIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKK 2263
YC GVE+M +N+LEQ WIR++FE P + + ++++K+ L RL+RST+FEEFL +K
Sbjct: 212 MAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRK 271
Query: 2262 WPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILS 2083
W SEKRFGLEGCEVLIPA+K +ID SS GVD ++GMPHRGRLNVLANV R+ L I
Sbjct: 272 WSSEKRFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFC 331
Query: 2082 QF-STLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAE 1906
QF S LE ADEGSGDVKYHLG+ R+NR + +N+ +++VANPSHLEA DPVVMGK +AE
Sbjct: 332 QFDSKLEAADEGSGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAE 391
Query: 1905 AFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTD 1726
FY GD + + M+ILLHGDAAFAGQG+V ETF+L DLPSYTTHG +H+VVNNQIGFTTD
Sbjct: 392 QFYCGDTEGKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTD 451
Query: 1725 PRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRH 1546
PR +RSSPY TDV RVV PIFHVN DDPEAVM+VC VAA+WR TF KDV+VDLVCYRR+
Sbjct: 452 PRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCYRRN 511
Query: 1545 GHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYE 1366
GHNE+DEPMFTQPLMY++I++ K L+KY E ++++GV N+ +EE++KY I E+A+
Sbjct: 512 GHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFA 571
Query: 1365 NAQKVTYVRNRDWLDSPWDDFFK---KRDPLKLPSTGXXXXXXXXXIGKFSQYP-EGFNL 1198
++ + + WLDSPW FF + + PSTG S P E F +
Sbjct: 572 RSKDEKILHIKHWLDSPWPGFFTLDGQPRSMSCPSTGLTEDILTHIGNVASSVPVENFTI 631
Query: 1197 HRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLH 1018
H GL R LK R +M+K+ ++DWA E +AFGSLLKEGIH+RLSGQDV+RGTFSHRHHVLH
Sbjct: 632 HGGLSRILKTRGEMVKNRTVDWALAEYMAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLH 691
Query: 1017 DQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFS 838
DQ VD++ P+N L Q YTVCNSSLSEY VLGFE G M PN+LV+WEAQFGDF
Sbjct: 692 DQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFEAGLRMASPNALVLWEAQFGDFH 751
Query: 837 NTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI--D 664
NTAQCIIDQFI GQ+KW+RQ+G+V+LLPHG EGMGPEHSSARPERFLQMCN+D ++ D
Sbjct: 752 NTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPD 811
Query: 663 LEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPM 484
L+ E F+ QL+D NW+V NC+TP N +H+LRRQ+ +PFRKP ++F+PKSLLRHP
Sbjct: 812 LK----EANFDINQLYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPE 867
Query: 483 ARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVAL 304
ARS ++ G++FQRVIPE G +QNP +VKR++FCTGKVYYD+ RK VA+
Sbjct: 868 ARSSFDEMLPGTHFQRVIPEDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAI 927
Query: 303 VRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYA 124
R+EQLSPFP+DL+ +E +KY AE+ W QEEHKN G + +V+PR+ + +S + YA
Sbjct: 928 TRIEQLSPFPFDLLLKEVQKYPNAELAWCQEEHKNQGYYDYVKPRLRTTIS-RAKPVWYA 986
Query: 123 GRLPSSSPATGNKFTH 76
GR P+++PATGNK TH
Sbjct: 987 GRNPAAAPATGNKKTH 1002
>gi|2160381|dbj|BAA06836.1| 2-oxoglutarate dehydrogenase [Homo
sapiens]
Length = 1002
Score = 1134 bits (2933), Expect = 0.0
Identities = 556/976 (56%), Positives = 708/976 (71%), Gaps = 13/976 (1%)
Frame = -1
Query: 2964 AAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXA 2785
+A V EPFL+G+SS Y+E+MY AWL++P SVH SWD +FRN
Sbjct: 41 SAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNAGAPPGTA-------- 92
Query: 2784 YAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLG 2605
Y L +S + + N + + DHL +Q LIR+YQ RGH++A LDPLG
Sbjct: 93 YQSPLPLSRGSLAAVAHAQSLVEAQPNVD-KLVEDHLAVQSLIRAYQIRGHHVAQLDPLG 151
Query: 2604 INSADLDDTIPPEL-----ELSFYGLGERDLDREFLLPPTTFISEKKS-LTLREILQRLK 2443
I ADLD ++P ++ +L FYGL E DLD+ F LP TTFI ++S L LREI++RL+
Sbjct: 152 ILDADLDSSVPADIISSTDKLGFYGLDESDLDKVFHLPTTTFIGGQESALPLREIIRRLE 211
Query: 2442 DIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKK 2263
YC GVE+M +N+LEQ WIR++FE P + + ++++K+ L RL+RST+FEEFL +K
Sbjct: 212 MAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRK 271
Query: 2262 WPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILS 2083
W SEKRFGLEGCEVLIPA+K +ID SS GVD ++GMPHRGRLNVLANV R+ L I
Sbjct: 272 WSSEKRFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFC 331
Query: 2082 QF-STLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAE 1906
QF S LE ADEGSGDVKYHLG+ R+NR + +N+ +++VANPSHLEA DPVVMGK +AE
Sbjct: 332 QFDSKLEAADEGSGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAE 391
Query: 1905 AFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTD 1726
FY GD + + M+ILLHGDAAFAGQG+V ETF+L DLPSYTTHG +H+VVNNQIGFTTD
Sbjct: 392 QFYCGDTEGKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTD 451
Query: 1725 PRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRH 1546
PR +RSSPY TDV RVV PIFHVN DDPEAVM+VC VAA+WR TF KDV+VDLVCYRR+
Sbjct: 452 PRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCYRRN 511
Query: 1545 GHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYE 1366
GHNE+DEPMFTQPLMY++I++ K L+KY E ++++GV N+ +EE++KY I E+A+
Sbjct: 512 GHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFA 571
Query: 1365 NAQKVTYVRNRDWLDSPWDDFFK---KRDPLKLPSTGXXXXXXXXXIGKFSQYP-EGFNL 1198
++ + + WLDSPW FF + + PSTG S P E F +
Sbjct: 572 RSKDEKILHIKHWLDSPWPGFFTLDGQPRSMSCPSTGLTEDILTHIGNVASSVPVENFTI 631
Query: 1197 HRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLH 1018
H GL R LK R +M+K+ ++DWA E +AFGSLLKEGIH+RLSGQDV+RGTFSHRHHVLH
Sbjct: 632 HGGLSRILKTRGEMVKNRTVDWALAEYMAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLH 691
Query: 1017 DQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFS 838
DQ VD++ P+N L Q YTVCNSSLSEY VLGFE G M PN+LV+WEAQFGDF
Sbjct: 692 DQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFEAGLRMASPNALVLWEAQFGDFH 751
Query: 837 NTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI--D 664
NTAQCIIDQFI GQ+KW+RQ+G+V+LLPHG EGMGPEHSSARPERFLQMCN+D ++ D
Sbjct: 752 NTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPD 811
Query: 663 LEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPM 484
L+ E F+ QL+D NW+V +C+TP N +H+LRRQ+ +PFRKP ++F+PKSLLRHP
Sbjct: 812 LK----EANFDINQLYDCNWVVVDCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPE 867
Query: 483 ARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVAL 304
ARS ++ G++FQRVIPE G +QNP +VKR++FCTGKVYYD+ RK VA+
Sbjct: 868 ARSSFDEMLPGTHFQRVIPEDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAI 927
Query: 303 VRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYA 124
R+EQLSPFP+DL+ +E +KY AE+ W QEEHKN G + +V+PR+ + +S + YA
Sbjct: 928 TRIEQLSPFPFDLLLKEVQKYPNAELAWCQEEHKNQGYYDYVKPRLRTTIS-RAKPVWYA 986
Query: 123 GRLPSSSPATGNKFTH 76
GR P+++PATGNK TH
Sbjct: 987 GRNPAAAPATGNKKTH 1002
>gi|34785384|gb|AAH57354.1| Ogdh protein [Mus musculus]
Length = 1034
Score = 1128 bits (2917), Expect = 0.0
Identities = 562/1016 (55%), Positives = 720/1016 (70%), Gaps = 35/1016 (3%)
Frame = -1
Query: 2964 AAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXA 2785
+A V EPFL+G+SS Y+E+MY AWL++P SVH SWD +FRN
Sbjct: 41 SAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNA--------------- 85
Query: 2784 YAGALGVSPAAAQVTTSSAPATRLDTNASVQS-----------ISDHLKIQLLIRSYQTR 2638
G P A + S + L T A QS + DHL +Q LIR+YQ R
Sbjct: 86 -----GAPPGTAYQSPLSLSRSSLATMAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQVR 140
Query: 2637 GHNIADLDPLGINSADLDD---TIPPELELS-------------FYGLGERDLDREFLLP 2506
GH+IA LDPLGI+ + DD T+ ++L+ FYGL E DLD+ F LP
Sbjct: 141 GHHIAKLDPLGISCVNFDDAPVTVSSNVDLAVFKERLRMLTVGGFYGLHESDLDKVFHLP 200
Query: 2505 PTTFIS-EKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHD 2329
TTFI ++ +L LREI++RL+ YC GVE+M +N+LEQ WIR++FE P + + +++
Sbjct: 201 TTTFIGGQEPALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNE 260
Query: 2328 QKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGM 2149
+K+ L RL+RST+FEEFL +KW SEKRFGLEGCEVLIPA+K +ID SS GVD ++GM
Sbjct: 261 EKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDMSSANGVDYVIMGM 320
Query: 2148 PHRGRLNVLANVCRQPLATILSQF-STLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIA 1972
PHRGRLNVLANV R+ L I QF S LE ADEGSGD+KYHLG+ R+NR + +N+ ++
Sbjct: 321 PHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDMKYHLGMYHRRINRVTDRNITLS 380
Query: 1971 VVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDL 1792
+VANPSHLEA DPVVMGK +AE FY GD + + M+ILLHGDAAFAGQG+V ETF+L DL
Sbjct: 381 LVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKVMSILLHGDAAFAGQGIVYETFHLSDL 440
Query: 1791 PSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNV 1612
PSYTTHG +H+VVNNQIGFTTDPR +RSSPY TDV RVV PIFHVN DDPEAVM+VC V
Sbjct: 441 PSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKV 500
Query: 1611 AADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGV 1432
AA+WR TF KDV+VDLVCYRR+GHNE+DEPMFTQPLMY++I++ K L+KY E ++++GV
Sbjct: 501 AAEWRNTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGV 560
Query: 1431 ANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFK---KRDPLKLPSTGX 1261
NE +EE++KY I E+A+ ++ + + WLDSPW FF + + PSTG
Sbjct: 561 VNEPEYEEEISKYDKICEEAFTRSKDEKILHIKHWLDSPWPGFFTLDGQPRSMTCPSTGL 620
Query: 1260 XXXXXXXXIGKFSQYP-EGFNLHRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGI 1084
S P E F +H GL R LK R++++ + ++DWA E +AFGSLLKEGI
Sbjct: 621 EEDVLFHIGKVASSVPVENFTIHGGLSRILKTRRELVTNRTVDWALAEYMAFGSLLKEGI 680
Query: 1083 HVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFE 904
HVRLSGQDV+RGTFSHRHHVLHDQ VD++ P+N L Q YTVCNSSLSEY VLGFE
Sbjct: 681 HVRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFE 740
Query: 903 LGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPE 724
LG++M PN+LV+WEAQFGDF+N AQCIIDQFI GQ+KW+RQ+G+V+LLPHG EGMGPE
Sbjct: 741 LGFAMASPNALVLWEAQFGDFNNMAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPE 800
Query: 723 HSSARPERFLQMCNEDDEI--DLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQ 550
HSSARPERFLQMCN+D ++ DL+ E F+ QL+D NWIV NC+TP N +H+LRRQ
Sbjct: 801 HSSARPERFLQMCNDDPDVLPDLQ----EENFDINQLYDCNWIVVNCSTPGNFFHVLRRQ 856
Query: 549 VTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCT 370
+ +PFRKP +VF+PKSLLRHP AR+ ++ G++FQRVIPE G +Q+P VKR++FCT
Sbjct: 857 ILLPFRKPLIVFTPKSLLRHPEARTSFDEMLPGTHFQRVIPENGPAAQDPHKVKRLLFCT 916
Query: 369 GKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGA 190
GKVYYD+ RK E +VA+ R+EQLSPFP+DL+ +E +KY AE+ W QEEHKN G
Sbjct: 917 GKVYYDLTRERKARNMEEEVAITRIEQLSPFPFDLLLKEAQKYPNAELAWCQEEHKNQGY 976
Query: 189 WSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGVPKSK 22
+ +V+PR+ + + + YAGR P+++PATGNK TH+ E + + F + K
Sbjct: 977 YDYVKPRLRTTID-RAKPVWYAGRDPAAAPATGNKKTHLTELQRFLDTAFDLDAFK 1031
>gi|33563270|ref|NP_035086.1| oxoglutarate dehydrogenase (lipoamide);
alpha-ketoglutarate dehydrogenase [Mus musculus]
gi|46397861|sp|Q60597|ODO1_MOUSE 2-oxoglutarate dehydrogenase E1
component, mitochondrial precursor (Alpha-ketoglutarate
dehydrogenase)
gi|29145087|gb|AAH49104.1| Oxoglutarate dehydrogenase (lipoamide)
[Mus musculus]
Length = 1019
Score = 1125 bits (2911), Expect = 0.0
Identities = 557/1001 (55%), Positives = 714/1001 (70%), Gaps = 20/1001 (1%)
Frame = -1
Query: 2964 AAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXA 2785
+A V EPFL+G+SS Y+E+MY AWL++P SVH SWD +FRN
Sbjct: 41 SAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNA--------------- 85
Query: 2784 YAGALGVSPAAAQVTTSSAPATRLDTNASVQS-----------ISDHLKIQLLIRSYQTR 2638
G P A + S + L T A QS + DHL +Q LIR+YQ R
Sbjct: 86 -----GAPPGTAYQSPLSLSRSSLATMAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQVR 140
Query: 2637 GHNIADLDPLGINSADLDDT-IPPELELSFYGLGERDLDREFLLPPTTFIS-EKKSLTLR 2464
GH+IA LDPLGI+ + DD + + FYGL E DLD+ F LP TTFI ++ +L LR
Sbjct: 141 GHHIAKLDPLGISCVNFDDAPVTVSSNVGFYGLHESDLDKVFHLPTTTFIGGQEPALPLR 200
Query: 2463 EILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKF 2284
EI++RL+ YC GVE+M +N+LEQ WIR++FE P + + ++++K+ L RL+RST+F
Sbjct: 201 EIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRF 260
Query: 2283 EEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQ 2104
EEFL +KW SEKRFGLEGCEVLIPA+K +ID SS GVD ++GMPHRGRLNVLANV R+
Sbjct: 261 EEFLQRKWSSEKRFGLEGCEVLIPALKTIIDMSSANGVDYVIMGMPHRGRLNVLANVIRK 320
Query: 2103 PLATILSQF-STLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVV 1927
L I QF S LE ADEGSGD+KYHLG+ R+NR + +N+ +++VANPSHLEA DPVV
Sbjct: 321 ELEQIFCQFDSKLEAADEGSGDMKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVV 380
Query: 1926 MGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNN 1747
MGK +AE FY GD + + M+ILLHGDAAFA QG+V ETF+L DLPSYTTHG +H+VVNN
Sbjct: 381 MGKTKAEQFYCGDTEGKKVMSILLHGDAAFAVQGIVYETFHLSDLPSYTTHGTVHVVVNN 440
Query: 1746 QIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVD 1567
QIGFTTDPR +RSSPY TDV RVV PIFHVN DDPEAVM+VC VAA+WR TF KDV+VD
Sbjct: 441 QIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRNTFHKDVVVD 500
Query: 1566 LVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGS 1387
LVCYRR+GHNE+DEPMFTQPLMY++I++ K L+KY E ++++G N+ +EE++KY
Sbjct: 501 LVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGFVNQPEYEEEISKYDK 560
Query: 1386 ILEDAYENAQKVTYVRNRDWLDSPWDDFFK---KRDPLKLPSTGXXXXXXXXXIGKFSQY 1216
I E+A+ ++ + + WLDSPW FF + + PSTG S
Sbjct: 561 ICEEAFTRSKDEKILHIKHWLDSPWPGFFTLDGQPRSMTCPSTGLEEDVLFHIGKVASSV 620
Query: 1215 P-EGFNLHRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFS 1039
P E F +H GL R LK R++++ + ++DWA E +AFGSLLKEGIHVRLSGQDV+RGTFS
Sbjct: 621 PVENFTIHGGLSRILKTRRELVTNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFS 680
Query: 1038 HRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWE 859
HRHHVLHDQ VD++ P+N L Q YTVCNSSLSEY VLGFELG++M PN+LV+WE
Sbjct: 681 HRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWE 740
Query: 858 AQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNE 679
AQFGDF+N AQCIIDQFI GQ+KW+RQ+G+V+LLPHG EGMGPEHSSARPERFLQMCN+
Sbjct: 741 AQFGDFNNMAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCND 800
Query: 678 DDEI--DLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPK 505
D ++ DL+ E F+ QL+D NWIV NC+TP N +H+LRRQ+ +PFRKP +VF+PK
Sbjct: 801 DPDVLPDLQ----EENFDINQLYDCNWIVVNCSTPGNFFHVLRRQILLPFRKPLIVFTPK 856
Query: 504 SLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVG 325
SLLRHP AR+ ++ G++FQRVIPE G +Q+P VKR++FCTGKVYYD+ RK
Sbjct: 857 SLLRHPEARTSFDEMLPGTHFQRVIPENGPAAQDPHKVKRLLFCTGKVYYDLTRERKARN 916
Query: 324 KENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSID 145
E +VA+ R+EQLSPFP+DL+ +E +KY AE+ W QEEHKN G + +V+PR+ + +
Sbjct: 917 MEEEVAITRIEQLSPFPFDLLLKEAQKYPNAELAWCQEEHKNQGYYDYVKPRLRTTID-R 975
Query: 144 GRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGVPKSK 22
+ YAGR P+++PATGNK TH+ E + + F + K
Sbjct: 976 AKPVWYAGRDPAAAPATGNKKTHLTELQRFLDTAFDLDAFK 1016
>gi|29421218|dbj|BAA86604.2| KIAA1290 protein [Homo sapiens]
Length = 1011
Score = 1124 bits (2907), Expect = 0.0
Identities = 550/977 (56%), Positives = 708/977 (72%), Gaps = 11/977 (1%)
Frame = -1
Query: 2931 GSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAA 2752
G S Y+E+MY AWL++P SVH SWD++FR ++G+ P +
Sbjct: 47 GGGSSYMEEMYFAWLENPQSVHKSWDSFFREASEEA-------------FSGSAQPRPPS 93
Query: 2751 AQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIP 2572
+ SA ++R T+ V+ DHL +Q LIR+YQ RGH++A LDPLGI ADLD +P
Sbjct: 94 VVHESRSAVSSRTKTSKLVE---DHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSFVP 150
Query: 2571 PEL-----ELSFYGLGERDLDREFLLPPTTFIS-EKKSLTLREILQRLKDIYCTSTGVEY 2410
+L +L+FY L E DLD+EF LP TTFI + +L+LREI++RL++ YC G+E+
Sbjct: 151 SDLITTIDKLAFYDLQEADLDKEFQLPTTTFIGGSENTLSLREIIRRLENTYCQHIGLEF 210
Query: 2409 MHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEG 2230
M +N++EQ WIR++FE P V + S ++K+ L RL+RS +FE+FLA+KW SEKRFGLEG
Sbjct: 211 MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG 270
Query: 2229 CEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFST-LEPADE 2053
CEV+IPA+K +ID SS +G+++ ++GMPHRGRLNVLANV R+ L I QF LE ADE
Sbjct: 271 CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE 330
Query: 2052 GSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDR 1873
GSGDVKYHLG+ ER+NR + +N+ +++VANPSHLEAVDPVV GK +AE FY GD + +
Sbjct: 331 GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK 390
Query: 1872 TMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCT 1693
M+IL+HGDAAFAGQGVV ETF+L DLPSYTT+G +H+VVNNQIGFTTDPR +RSSPY T
Sbjct: 391 VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT 450
Query: 1692 DVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFT 1513
DV RVV PIFHVN DDPEAV++VC+VAA+WR TF KDV+VDLVCYRR GHNE+DEPMFT
Sbjct: 451 DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT 510
Query: 1512 QPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNR 1333
QPLMY++I + L+KY +K++ EG Q +EE+ KY I E+AY ++ + +
Sbjct: 511 QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK 570
Query: 1332 DWLDSPWDDFFK---KRDPLKLPSTGXXXXXXXXXIGKFSQYP-EGFNLHRGLERTLKGR 1165
WLDSPW FF + + P+TG S P E F +H GL R L+GR
Sbjct: 571 HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR 630
Query: 1164 QQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNP 985
M K+ ++DWA E +AFGSLLKEGIHVRLSGQDV+RGTFSHRHHVLHDQ+VD++ P
Sbjct: 631 ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP 690
Query: 984 LNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFI 805
+N L Q YTVCNSSLSEY VLGFELGY+M PN+LV+WEAQFGDF NTAQCIIDQFI
Sbjct: 691 MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI 750
Query: 804 SSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQ 625
S+GQ+KW+R +G+V+LLPHG EGMGPEHSSARPERFLQM N+D + AF FE
Sbjct: 751 STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSD---AYPAFTKDFEVS 807
Query: 624 QLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSN 445
QL+D NWIV NC+TPAN +H+LRRQ+ +PFRKP ++F+PKSLLRHP A+S + SG++
Sbjct: 808 QLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTS 867
Query: 444 FQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDL 265
FQRVIPE GA ++ P V+R++FCTGKVYYD+V R E VA+ R+EQ+SPFP+DL
Sbjct: 868 FQRVIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDL 927
Query: 264 VQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNK 85
++QE KY GAE+ W QEEHKNMG + ++ PR ++L R Y GR P+++PATGN+
Sbjct: 928 IKQEAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILR-RARPIWYVGRDPAAAPATGNR 986
Query: 84 FTHMQEQKEMMSKVFGV 34
TH+ K+ + F +
Sbjct: 987 NTHLVSLKKFLDTAFNL 1003
>gi|8922716|ref|NP_060715.1| oxoglutarate dehydrogenase-like [Homo
sapiens]
gi|7023145|dbj|BAA91855.1| unnamed protein product [Homo sapiens]
Length = 1010
Score = 1121 bits (2900), Expect = 0.0
Identities = 549/977 (56%), Positives = 707/977 (72%), Gaps = 11/977 (1%)
Frame = -1
Query: 2931 GSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAA 2752
G S Y+E+MY AWL++P SVH SWD++FR ++G+ P +
Sbjct: 46 GGGSSYMEEMYFAWLENPQSVHKSWDSFFREASEEA-------------FSGSAQPRPPS 92
Query: 2751 AQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIP 2572
SA ++R T+ V+ DHL +Q LIR+YQ RGH++A LDPLGI ADLD +P
Sbjct: 93 VVHEGRSAVSSRTKTSKLVE---DHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSFVP 149
Query: 2571 PEL-----ELSFYGLGERDLDREFLLPPTTFIS-EKKSLTLREILQRLKDIYCTSTGVEY 2410
+L +L+FY L E DLD+EF LP TTFI + +L+LREI++RL++ YC G+E+
Sbjct: 150 SDLITTIDKLAFYDLQEADLDKEFQLPTTTFIGGSENTLSLREIIRRLENTYCQHIGLEF 209
Query: 2409 MHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEG 2230
M +N++EQ WIR++FE P V + S ++K+ L RL+RS +FE+FLA+KW SEKRFGLEG
Sbjct: 210 MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG 269
Query: 2229 CEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFST-LEPADE 2053
CEV+IPA+K +ID SS +G+++ ++GMPHRGRLNVLANV R+ L I +F LE ADE
Sbjct: 270 CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCRFDPKLEAADE 329
Query: 2052 GSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDR 1873
GSGDVKYHLG+ ER+NR + +N+ +++VANPSHLEAVDPVV GK +AE FY GD + +
Sbjct: 330 GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK 389
Query: 1872 TMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCT 1693
M+IL+HGDAAFAGQGVV ETF+L DLPSYTT+G +H+VVNNQIGFTTDPR +RSSPY T
Sbjct: 390 VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT 449
Query: 1692 DVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFT 1513
DV RVV PIFHVN DDPEAV++VC+VAA+WR TF KDV+VDLVCYRR GHNE+DEPMFT
Sbjct: 450 DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT 509
Query: 1512 QPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNR 1333
QPLMY++I + L+KY +K++ EG Q +EE+ KY I E+AY ++ + +
Sbjct: 510 QPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK 569
Query: 1332 DWLDSPWDDFFK---KRDPLKLPSTGXXXXXXXXXIGKFSQYP-EGFNLHRGLERTLKGR 1165
WLDSPW FF + + P+TG S P E F +H GL R L+GR
Sbjct: 570 HWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR 629
Query: 1164 QQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNP 985
M K+ ++DWA E +AFGSLLKEGIHVRLSGQDV+RGTFSHRHHVLHDQ+VD++ P
Sbjct: 630 ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP 689
Query: 984 LNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFI 805
+N L Q YTVCNSSLSEY VLGFELGY+M PN+LV+WEAQFGDF NTAQCIIDQFI
Sbjct: 690 MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI 749
Query: 804 SSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQ 625
S+GQ+KW+R +G+V+LLPHG EGMGPEHSSARPERFLQM N+D + AF FE
Sbjct: 750 STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSD---AYPAFTKDFEVS 806
Query: 624 QLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSN 445
QL+D NWIV NC+TPAN +H+LRRQ+ +PFRKP ++F+PKSLLRHP A+S + SG++
Sbjct: 807 QLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTS 866
Query: 444 FQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDL 265
FQRVIPE GA ++ P V+R++FCTGKVYYD+V R E VA+ R+EQ+SPFP+DL
Sbjct: 867 FQRVIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDL 926
Query: 264 VQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNK 85
++QE KY GAE+ W QEEHKNMG + ++ PR ++L R Y GR P+++PATGN+
Sbjct: 927 IKQEAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILR-RARPIWYVGRDPAAAPATGNR 985
Query: 84 FTHMQEQKEMMSKVFGV 34
TH+ K+ + F +
Sbjct: 986 NTHLVSLKKFLDTAFNL 1002
>gi|20072238|gb|AAH26320.1| Oxoglutarate dehydrogenase-like [Homo
sapiens]
Length = 1010
Score = 1118 bits (2892), Expect = 0.0
Identities = 548/977 (56%), Positives = 707/977 (72%), Gaps = 11/977 (1%)
Frame = -1
Query: 2931 GSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAA 2752
G S Y+E+MY AWL++P SVH SWD++FR ++G+ P +
Sbjct: 46 GGGSSYMEEMYFAWLENPQSVHKSWDSFFREASEEA-------------FSGSAQPRPPS 92
Query: 2751 AQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIP 2572
+ SA ++R T+ V+ DHL +Q LIR+YQ RGH++A LDPLGI ADLD +P
Sbjct: 93 VVHESRSAVSSRTKTSKLVE---DHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSFVP 149
Query: 2571 PEL-----ELSFYGLGERDLDREFLLPPTTFIS-EKKSLTLREILQRLKDIYCTSTGVEY 2410
+L +L+FY L E DLD+EF LP TTFI + +L+LREI++RL++ YC G+E+
Sbjct: 150 SDLITTIDKLAFYDLQEADLDKEFQLPTTTFIGGSENTLSLREIIRRLENTYCQHIGLEF 209
Query: 2409 MHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEG 2230
M +N++EQ WIR++FE P V + S ++K+ L RL+RS +FE+FLA+KW SEKRFGLEG
Sbjct: 210 MFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEG 269
Query: 2229 CEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFST-LEPADE 2053
CEV+IPA+K +ID SS +G+++ ++GMPHRGRLNVLANV R+ L I QF LE ADE
Sbjct: 270 CEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADE 329
Query: 2052 GSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDR 1873
GSGDVKYHLG+ ER+NR + +N+ +++VANPSHLEAVDPVV GK +AE FY GD + +
Sbjct: 330 GSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKK 389
Query: 1872 TMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCT 1693
M+IL+HGDAAFAGQGVV ETF+L DLPSYTT+G +H+VVNNQIGFTTDPR +RSSPY T
Sbjct: 390 VMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPT 449
Query: 1692 DVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFT 1513
DV RVV PIFHVN DDPEAV++VC+VAA+WR TF KDV+VDLVCYRR GHNE+DEPMFT
Sbjct: 450 DVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFT 509
Query: 1512 QPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNR 1333
Q LMY++I + L+KY +K++ EG Q +EE+ KY I E+AY ++ + +
Sbjct: 510 QLLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIK 569
Query: 1332 DWLDSPWDDFFK---KRDPLKLPSTGXXXXXXXXXIGKFSQYP-EGFNLHRGLERTLKGR 1165
WL+SPW FF + + P+TG S P E F +H GL R L+GR
Sbjct: 570 HWLNSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGR 629
Query: 1164 QQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNP 985
M K+ ++DWA E +AFGSLLKEGIHVRLSGQDV+RGTFSHRHHVLHDQ+VD++ P
Sbjct: 630 ADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVP 689
Query: 984 LNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFI 805
+N L Q YTVCNSSLSEY VLGFELGY+M PN+LV+WEAQFGDF NTAQCIIDQFI
Sbjct: 690 MNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFI 749
Query: 804 SSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQ 625
S+GQ+KW+R +G+V+LLPHG EGMGPEHSSARPERFLQM N+D + AF FE
Sbjct: 750 STGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSD---AYPAFTKDFEVS 806
Query: 624 QLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSN 445
QL+D NWIV NC+TPAN +H+LRRQ+ +PFRKP ++F+PKSLLRHP A+S + SG++
Sbjct: 807 QLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTS 866
Query: 444 FQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDL 265
FQRVIPE GA ++ P V+R++FCTGKVYYD+V R E VA+ R+EQ+SPFP+DL
Sbjct: 867 FQRVIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDL 926
Query: 264 VQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNK 85
++QE KY GAE+ W QEEHKNMG + ++ PR ++L R Y GR P+++PATGN+
Sbjct: 927 IKQEAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILR-RARPIWYVGRDPAAAPATGNR 985
Query: 84 FTHMQEQKEMMSKVFGV 34
TH+ K+ + F +
Sbjct: 986 NTHLVSLKKFLDTAFNL 1002
>gi|38075902|ref|XP_138959.3| similar to KIAA1290 protein [Mus
musculus]
Length = 1043
Score = 1115 bits (2883), Expect = 0.0
Identities = 549/985 (55%), Positives = 702/985 (70%), Gaps = 18/985 (1%)
Frame = -1
Query: 2934 NGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPA 2755
+G SS Y+E+MY AWL++P SVH SWD++F+ V PA
Sbjct: 78 SGVSSSYVEEMYFAWLENPQSVHKSWDSFFQRASKEAS------------------VGPA 119
Query: 2754 AAQVTTSSAPATRLDTNASVQS-------ISDHLKIQLLIRSYQTRGHNIADLDPLGINS 2596
Q+ PA ++ SV S + DHL +Q LIR+YQ RGH++A LDPLGI
Sbjct: 120 QPQL-----PAVLQESRTSVSSCTKTSKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILD 174
Query: 2595 ADLDDTIPPEL-----ELSFYGLGERDLDREFLLPPTTFIS-EKKSLTLREILQRLKDIY 2434
ADLD +P +L +L+FY L E DLD+EF LP TTFI + +L+LREI++RL+ Y
Sbjct: 175 ADLDSFVPSDLITTIDKLAFYDLQEADLDKEFRLPTTTFIGGPENTLSLREIIRRLESTY 234
Query: 2433 CTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPS 2254
C G+E+M +N++EQ WIR++FE P V + S ++K+ L RL+RS +FE+FLA+KW S
Sbjct: 235 CQHIGLEFMFINDVEQCQWIRQKFETPGVMQFSVEEKRTLLARLVRSMRFEDFLARKWSS 294
Query: 2253 EKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS 2074
EKRFGLEGCEV+IPA+K +ID SS +G+++ ++GMPHRGRLNVLANV R+ L I QF
Sbjct: 295 EKRFGLEGCEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFD 354
Query: 2073 T-LEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFY 1897
LE ADEGSGDVKYHLG+ ER+NR + +N+ +++VANPSHLEAVDPVV GK +AE FY
Sbjct: 355 PKLEAADEGSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFY 414
Query: 1896 AGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRS 1717
GD + + M+IL+HGDAAFAGQGVV ETF+L DLPSYTT+G +H+VVNNQIGFTTDPR
Sbjct: 415 RGDAQGRKVMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRM 474
Query: 1716 SRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHN 1537
+RSSPY TDV RVV PIFHVN DDPEAV++VC+VAA+WR TF KDV+VDLVCYRR GHN
Sbjct: 475 ARSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHN 534
Query: 1536 ELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQ 1357
E+DEPMFTQPLMY++I + L+KY +K++ EG Q +EE+ KY I E+AY ++
Sbjct: 535 EMDEPMFTQPLMYKQIHKQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSK 594
Query: 1356 KVTYVRNRDWLDSPWDDFFK---KRDPLKLPSTGXXXXXXXXXIGKFSQYP-EGFNLHRG 1189
+ + WLDSPW FF + + P+TG S P E F +H G
Sbjct: 595 DKKILHIKHWLDSPWPGFFNVDGEPKSMTCPTTGIPEEMLTHIGSVASSVPLEDFKIHTG 654
Query: 1188 LERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQK 1009
L R L+GR M K ++DWA E +AFGSLLKEGIHVRLSGQDV+RGTFSHRHHVLHDQ+
Sbjct: 655 LSRILRGRADMTKKRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQE 714
Query: 1008 VDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTA 829
VD++ P+N L Q YTVCNSSLSEY VLGFELGY+M PN+LV+WEAQFGDF NTA
Sbjct: 715 VDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTA 774
Query: 828 QCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIA 649
QCIIDQFIS+GQ+KW+R +G+V+LLPHG EGMGPEHSSARPERFLQM N+D +
Sbjct: 775 QCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSD---AYPV 831
Query: 648 FEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPV 469
F FE QL+D NWIV NC+TPA+ +H+LRRQ+ +PFRKP +VF+PKSLLRHP A+S
Sbjct: 832 FTEDFEVSQLYDCNWIVVNCSTPASYFHVLRRQILLPFRKPLIVFTPKSLLRHPDAKSSF 891
Query: 468 EDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQ 289
+ SG++FQR+IPE G + +P V+R++FCTGKVYYD+V R G E VA+ R+EQ
Sbjct: 892 DQMVSGTSFQRLIPEDGPAAHSPEQVQRLIFCTGKVYYDLVKERSSQGLEQQVAITRLEQ 951
Query: 288 LSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPS 109
+SPFP+DL+ +E KY GAE++W QEEHKNMG + ++ PR +LL R Y GR P+
Sbjct: 952 ISPFPFDLIMREAEKYSGAELVWCQEEHKNMGYYDYISPRFMTLLG-HSRPIWYVGRDPA 1010
Query: 108 SSPATGNKFTHMQEQKEMMSKVFGV 34
++PATGNK H+ + + F +
Sbjct: 1011 AAPATGNKNAHLVSLRRFLDTAFNL 1035
>gi|47210299|emb|CAF94599.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1070
Score = 1107 bits (2864), Expect = 0.0
Identities = 563/1044 (53%), Positives = 709/1044 (66%), Gaps = 66/1044 (6%)
Frame = -1
Query: 2955 VKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAG 2776
V EPFLNG+SS Y+E+MY AWL++P SVH SWD +FRN
Sbjct: 50 VASEPFLNGTSSNYVEEMYYAWLENPKSVHKSWDVFFRNANA------------------ 91
Query: 2775 ALGVSPAAA-QVTTSSAPATRLDTNASVQS-----ISDHLKIQLLIRSYQTRGHNIADLD 2614
G P AA Q + + A RL + Q + DHL +Q LIR+YQ RGH +A LD
Sbjct: 92 --GAPPGAAYQSPLALSAAPRLSSLVGAQPNVEKLVEDHLAVQSLIRAYQIRGHQVAQLD 149
Query: 2613 PLGINSADLDDTIPPEL-----ELSFYGLGERDLDREFLLPPTTFISEKKS-LTLREILQ 2452
PLGI ADLD +P ++ +L FYGL E DLD+ F LP TTFI +S L L+EI++
Sbjct: 150 PLGIMDADLDSCVPTDIITSSDKLGFYGLDESDLDKVFRLPTTTFIGGSESALPLKEIIR 209
Query: 2451 RLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTK----- 2287
RL+ YC GVE+M +N+LEQ WIR++FE P V + + ++K+ L R++RST+
Sbjct: 210 RLEMSYCQHIGVEFMFINDLEQCQWIRQKFETPGVMQFTLEEKRTLLARMVRSTRRCLPG 269
Query: 2286 -------FEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLN 2128
FEEFL KKW +EKRFGLEGCE LIPA+K +ID SS GVD ++GMPHRGRLN
Sbjct: 270 STSTVCRFEEFLQKKWSAEKRFGLEGCESLIPALKTIIDKSSEKGVDYVIMGMPHRGRLN 329
Query: 2127 VLANVCRQPLATILSQF-STLEPADE------------------------GSGDVKYHLG 2023
VLANV R+ L I QF S LE ADE GSGDVKYHLG
Sbjct: 330 VLANVIRKELEQIFCQFDSKLEAADEVTGSQRARACVRACMLLTLLLLSQGSGDVKYHLG 389
Query: 2022 VCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDA 1843
+ R+NR + +N+ +++VANPSHLEAVDPVV GK +AE FY GD R M+ILLHGDA
Sbjct: 390 MYHRRINRVTDRNITLSLVANPSHLEAVDPVVQGKTKAEQFYCGDNDGKRVMSILLHGDA 449
Query: 1842 AFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPI 1663
AFAGQG+V ETF+L DLPSYTTHG +H+VVNNQIGFTTDPR +RSSPY TDV RVV PI
Sbjct: 450 AFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRVARSSPYPTDVARVVNAPI 509
Query: 1662 FHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQ 1483
FHVN DDPEAV++VC VAA+WR TF KDV+VDLVCYRR GHNE+DEPMFTQPLMY++IK+
Sbjct: 510 FHVNADDPEAVIYVCKVAAEWRNTFHKDVVVDLVCYRRMGHNEMDEPMFTQPLMYKQIKK 569
Query: 1482 TKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPW--- 1312
K L+KY EK++ EG + Q +EE+ KY I E+AY ++ + + WLDSPW
Sbjct: 570 QKPVLQKYAEKLIAEGAVSRQEYEEEIAKYDKICEEAYARSKDEKILHIKHWLDSPWPGE 629
Query: 1311 DDFFKKRDPLK-------------LPSTGXXXXXXXXXIGKFSQYP-EGFNLHRGLERTL 1174
+R P++ PSTG S P E F +H GL R L
Sbjct: 630 QPGLSRRLPVRGFFTLEGQPKSMSCPSTGLTEDNLNHIGQVASSVPVEDFTIHGGLSRIL 689
Query: 1173 KGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKI 994
K R +M+++ +DWA GE +AFGSLLKEG H+RLSGQDV+RGTFSHRHHVLHDQ VD++I
Sbjct: 690 KARGEMVRNRVVDWALGEYMAFGSLLKEGTHIRLSGQDVERGTFSHRHHVLHDQNVDKRI 749
Query: 993 YNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIID 814
P+N L+ Q YTVCNSSLSEY VLGFELG++M PN+L++WEAQFGDF NTAQCIID
Sbjct: 750 CIPMNHLAPDQAPYTVCNSSLSEYGVLGFELGFAMASPNALILWEAQFGDFHNTAQCIID 809
Query: 813 QFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTF 634
QFI GQ+KW+RQ+G+V+LLPHG EGMGPEHSSARPERFLQMCN+D ++ F
Sbjct: 810 QFICPGQAKWVRQNGIVLLLPHGCEGMGPEHSSARPERFLQMCNDDPDV---MPVISDDF 866
Query: 633 EAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQS 454
QL+D NWIV NC+TPAN +H+LRRQ+ +PFRKP ++F+PKSLLRHP ARS +D
Sbjct: 867 AVHQLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDDMLP 926
Query: 453 GSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFP 274
G++FQR+IPE GA +Q P +VKR++FCTGKV+Y+++ RK E VA+ R+EQLSPFP
Sbjct: 927 GTHFQRLIPEDGAAAQRPEEVKRLIFCTGKVFYELIKDRKTREMEASVAISRIEQLSPFP 986
Query: 273 YDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPAT 94
+D V+ E ++ A+++W QEEHKN G + +V+PRI + + + YAGR P+S+PAT
Sbjct: 987 FDQVKAEVDRFPNADLVWCQEEHKNQGYYDYVKPRIRTTIQ-RAKPVWYAGREPASAPAT 1045
Query: 93 GNKFTHMQEQKEMMSKVFGVPKSK 22
GNK TH+ E + FG+ K
Sbjct: 1046 GNKNTHLMELRRFSDTAFGLDAFK 1069
>gi|34877017|ref|XP_214261.2| similar to KIAA1290 protein [Rattus
norvegicus]
Length = 1109
Score = 1106 bits (2861), Expect = 0.0
Identities = 553/997 (55%), Positives = 701/997 (69%), Gaps = 31/997 (3%)
Frame = -1
Query: 2931 GSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAA 2752
G S Y+E+MY AWL++P SVH SWD +F+ V PA
Sbjct: 132 GVSPSYVEEMYFAWLENPQSVHKSWDNFFQRATKEAS------------------VGPAQ 173
Query: 2751 AQVTTSSAPATRLDTNASVQS-------ISDHLKIQLLIRSYQTRGHNIADLDPLGINSA 2593
Q PA ++ ASV S + DHL +Q LIR+YQ RGH++A LDPLGI A
Sbjct: 174 PQ-----PPAVIQESRASVSSCTKTSKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDA 228
Query: 2592 DLDDTIPPEL-----ELSFYGLGERDLDREFLLPPTTFIS-EKKSLTLREILQRLKDIYC 2431
DLD +P +L +L+FY L E DLD+EF LP TTFI + +L+LREI++RL+ YC
Sbjct: 229 DLDSFVPSDLITTIDKLAFYDLQEADLDKEFRLPTTTFIGGSENTLSLREIIRRLESTYC 288
Query: 2430 TSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSE 2251
G+E+M +N++EQ WIR++FE P V + S ++K+ L RL+RS +FE+FLA+KW SE
Sbjct: 289 QHIGLEFMFINDVEQCQWIRQKFETPGVMKFSIEEKRTLLARLVRSMRFEDFLARKWSSE 348
Query: 2250 KRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFST 2071
KRFGLEGCEV+IPA+K +ID SS +GV++ ++GMPHRGRLNVLANV R+ L I QF
Sbjct: 349 KRFGLEGCEVMIPALKTIIDKSSEMGVENVILGMPHRGRLNVLANVIRKDLEQIFCQFDP 408
Query: 2070 -LEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYA 1894
LE ADEGSGDVKYHLG+ ER+NR + +N+ +++VANPSHLEAVDPVV GK +AE FY
Sbjct: 409 KLEAADEGSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYR 468
Query: 1893 GDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSS 1714
GD + + M+IL+HGDAAFAGQGVV ETF+L DLPSYTT+G +H+VVNNQIGFTTDPR +
Sbjct: 469 GDAQGRKVMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMA 528
Query: 1713 RSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNE 1534
RSSPY TDV RVV PIFHVN DDPEAV++VC+VAA+WR TF KDV+VDLVCYRR GHNE
Sbjct: 529 RSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNE 588
Query: 1533 LDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQK 1354
+DEPMFTQPLMY++I + L+KY +K++ EG Q +EE+ KY I E+AY ++
Sbjct: 589 MDEPMFTQPLMYKQIHKQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKD 648
Query: 1353 VTYVRNRDWLDSPWDDFFK---KRDPLKLPSTGXXXXXXXXXIGKFSQYP-EGFNLHR-- 1192
+ + WLDSPW FF + + P+TG S P E F +H
Sbjct: 649 KKILHIKHWLDSPWPGFFNVDGEPKSMTYPTTGIPEDTLSHIGNVASSVPLEDFKIHTGP 708
Query: 1191 -----------GLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGT 1045
GL R L+GR M K ++DWA E +AFGSLLKEGIHVRLSGQDV+RGT
Sbjct: 709 RLNRVPHPPPPGLSRILRGRADMTKKRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGT 768
Query: 1044 FSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVI 865
FSHRHHVLHDQ VD++ P+N L Q YTVCNSSLSEY VLGFELGY+M PN+LV+
Sbjct: 769 FSHRHHVLHDQDVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVL 828
Query: 864 WEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMC 685
WEAQFGDF NTAQCIIDQFIS+GQ+KW+R +G+V+LLPHG EGMGPEHSSARPERFLQM
Sbjct: 829 WEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMS 888
Query: 684 NEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPK 505
N+D + F FE QL+D NWIV NC+TPA+ +H+LRRQV +PFRKP +VF+PK
Sbjct: 889 NDDSD---AYPVFTEDFEVSQLYDCNWIVVNCSTPASYFHVLRRQVLLPFRKPLIVFTPK 945
Query: 504 SLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVG 325
SLLRHP A+S + SG++FQR+IPE G +Q+P V+R++FCTGKVYYD+V R G
Sbjct: 946 SLLRHPDAKSSFDQMVSGTSFQRMIPEDGPAAQSPERVERLIFCTGKVYYDLVKERSSQG 1005
Query: 324 KENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSID 145
E VA+ R+EQ+SPFP+DL+ +E KY GAE++W QEEHKNMG + ++ PR +LL
Sbjct: 1006 LEKQVAITRLEQISPFPFDLIMREAEKYSGAELVWCQEEHKNMGYYDYISPRFMTLLG-H 1064
Query: 144 GRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGV 34
R Y GR P+++PATGNK TH+ ++ + F +
Sbjct: 1065 SRPIWYVGREPAAAPATGNKNTHLVSLRKFLDTAFNL 1101
>gi|50749142|ref|XP_421503.1| PREDICTED: similar to KIAA1290 protein
[Gallus gallus]
Length = 1034
Score = 1095 bits (2832), Expect = 0.0
Identities = 549/1012 (54%), Positives = 706/1012 (69%), Gaps = 27/1012 (2%)
Frame = -1
Query: 2988 VQHRNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVH---TSWDAYFRNVEXXXXX 2818
V Q ++ EPFL+GS+S Y+E+MY AWL++P SVH A
Sbjct: 19 VLFHGQRYVSSGTSEPFLSGSNSNYVEEMYYAWLENPQSVHKCRARTRAVTHRSPAAERR 78
Query: 2817 XXXXXXXXXXAYAGALGVSPAAAQVTTSSAP------ATRLDTNASVQS-------ISDH 2677
A P + + +P A+ L ++ Q+ + DH
Sbjct: 79 ELSVVLKRPPRRVPAAREPPWPHRPHSEKSPDQLERKASFLQSHGLAQTPGKAEKLVEDH 138
Query: 2676 LKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPEL-----ELSFYGLGERDLDREFL 2512
L +Q LIR+YQ RGH++A LDPLGI ADLD +P +L +L FYGL E DLD+ F
Sbjct: 139 LAVQSLIRAYQIRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLGFYGLHESDLDKVFQ 198
Query: 2511 LPPTTFIS-EKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELS 2335
LP TTFI + SL+LREI++RL++ YC G+E+M +N++EQ WIR++FE P V + +
Sbjct: 199 LPTTTFIGGNENSLSLREIIKRLENTYCQQIGLEFMFINDVEQCQWIRQKFETPGVMKFT 258
Query: 2334 HDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVI 2155
+++K+ L RL+RS +FE+FLA+KW SEKRFGLEGCEV+IPA+K +ID SS +G++ ++
Sbjct: 259 NEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIEYVIM 318
Query: 2154 GMPHRGRLNVLANVCRQPLATILSQFST-LEPADEGSGDVKYHLGVCIERLNRQSQKNVK 1978
GMPHRGRLNVLANV R+ L I QF LE ADEGSGDVKYHLG+ ER+NR + K +
Sbjct: 319 GMPHRGRLNVLANVIRKELEQIFCQFDPKLEAADEGSGDVKYHLGMYHERINRATNKKIT 378
Query: 1977 IAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLD 1798
++++ANPSHLEAVDPVV GK +AE FY GD + M+ILLHGDAAFAGQGVV ETF+L
Sbjct: 379 LSLMANPSHLEAVDPVVQGKTKAEQFYRGDTAGKKVMSILLHGDAAFAGQGVVYETFHLS 438
Query: 1797 DLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVC 1618
DLPSYTT+G IH+VVNNQIGFTTDPR +RSSPY TDV RVV PIFHVN DDPEAVM+VC
Sbjct: 439 DLPSYTTNGTIHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVMYVC 498
Query: 1617 NVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNE 1438
+VAA+WR TF KDV+VDLVCYRR GHNE+DEPMFTQPLMY++I + L+KY +K++ +
Sbjct: 499 SVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHKQVPVLKKYADKLIAD 558
Query: 1437 GVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFK---KRDPLKLPST 1267
G Q +EE+ KY I E+AY ++ + + WLDSPW FF + + P T
Sbjct: 559 GTVTLQEFEEEIAKYDRICEEAYTRSKDNKILHIKHWLDSPWPGFFNVDGEPKSMSCPPT 618
Query: 1266 GXXXXXXXXXIGKFSQYP-EGFNLHRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKE 1090
G S P + F +H GL R L+ R +M K+ +DWA E +AFGS LKE
Sbjct: 619 GISEDLLTHIGNVASSVPVKDFKIHAGLSRILRARLEMTKNRVVDWALAEYMAFGSFLKE 678
Query: 1089 GIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLG 910
GIHVRLSGQDV+RGTFSHRHHVLHDQ+VD++ P+N L E Q YTVCNSSLSEY VLG
Sbjct: 679 GIHVRLSGQDVERGTFSHRHHVLHDQEVDKRTCVPMNHLWEQQAPYTVCNSSLSEYGVLG 738
Query: 909 FELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMG 730
FELG++M PN+LV WEAQFGDF NTAQCIIDQFISSGQ+KW+R +G+V+LLPHG EGMG
Sbjct: 739 FELGFAMASPNALVCWEAQFGDFHNTAQCIIDQFISSGQAKWVRHNGIVLLLPHGMEGMG 798
Query: 729 PEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQ 550
PEHSSARPERFLQM N+D + E F FE QL++ NWIV NC+TPAN +H+LRRQ
Sbjct: 799 PEHSSARPERFLQMSNDDSDAYPE---FTEQFEVSQLYECNWIVVNCSTPANYFHVLRRQ 855
Query: 549 VTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCT 370
+ +PFRKP +V +PKSLLRHP A+S ++ SG+ FQRVIPE G +Q P +VKRV+FCT
Sbjct: 856 ILLPFRKPLIVLTPKSLLRHPEAKSSFDEMVSGTTFQRVIPENGLAAQAPHEVKRVIFCT 915
Query: 369 GKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGA 190
GKVYYD+V RK+ E VA+ R+EQ+SPFP+DL+++E KY GA+++W QEEHKN G
Sbjct: 916 GKVYYDLVKERKNQDLEKQVAITRLEQISPFPFDLLKEELEKYPGADLVWCQEEHKNSGY 975
Query: 189 WSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGV 34
+ +V+PR ++++ R Y GR P+++ ATGNK TH+ + + F +
Sbjct: 976 YDYVKPRFRTIVN-HTRPIWYVGREPAAAAATGNKNTHLVSLRRFLDTAFNL 1026
>gi|47223283|emb|CAF98667.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1054
Score = 1088 bits (2814), Expect = 0.0
Identities = 555/1033 (53%), Positives = 701/1033 (67%), Gaps = 44/1033 (4%)
Frame = -1
Query: 3000 ASTLVQHRNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXX 2821
A+ +V R+ S A P S+ Y+E+MY +WL+DP SVH SWD +FRN+E
Sbjct: 38 AAGVVDRRSCSSGAVTG--PSALTSNPSYVEEMYFSWLEDPKSVHKSWDMFFRNMEASPS 95
Query: 2820 XXXXXXXXXXXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQT 2641
L S AQ + + DHL + LIR+YQT
Sbjct: 96 GEAADRRPSTLLRGRTLSHSSDVAQ-----------------KVVEDHLAVHTLIRAYQT 138
Query: 2640 RGHNIADLDPLGINSADLDDTIPPEL-----ELSFYGLGERDLDREFLLPPTTFIS-EKK 2479
RGH++A LDPLGI ADLD +P +L +L +Y L E DLDR F LP TTFI E
Sbjct: 139 RGHHVAQLDPLGILEADLDSFVPSDLITSIDKLGYYDLKESDLDRSFQLPSTTFIGGEDS 198
Query: 2478 SLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLI 2299
+L LREI++RL+ YC GVE+M +NN++Q WIR + E P + + K+ L RLI
Sbjct: 199 TLPLREIIRRLEMAYCGHIGVEFMFINNVDQCQWIRNKIETPGIMRFTDADKRTLLARLI 258
Query: 2298 RSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLA 2119
RST+FE+FLA+KW SEKRFGLEGCEVLIPA+K +ID SS GVDS ++GMPHRGRLNVLA
Sbjct: 259 RSTRFEDFLARKWSSEKRFGLEGCEVLIPALKTIIDESSAAGVDSVIMGMPHRGRLNVLA 318
Query: 2118 NVCRQPLATILSQFST-LEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEA 1942
NV R+ L I QF LE ADEGSGDVKYHLG+ ER+NR++ KN+ +++VANPSHLEA
Sbjct: 319 NVIRKDLDQIFCQFDPKLEAADEGSGDVKYHLGMYHERINRKTDKNITLSLVANPSHLEA 378
Query: 1941 VDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIH 1762
VDPVV GK +AE FY GD + + M+IL+HGDAAFAGQGVV ETF+L +LPSYTTHG IH
Sbjct: 379 VDPVVQGKTKAEQFYRGDVEGKKVMSILIHGDAAFAGQGVVYETFHLSELPSYTTHGTIH 438
Query: 1761 IVVNNQ---------------------------IGFTTDPRSSRSSPYCTDVGRVVGCPI 1663
+VVNNQ IGFTTDPR +RSSPY TDV RVV PI
Sbjct: 439 VVVNNQVSNSPPSVMQFRHFEEGQRKAVMVAPQIGFTTDPRVARSSPYPTDVARVVNAPI 498
Query: 1662 FHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQ 1483
FHVN DDPEAV++VC +AA+WR TF KDV++DLV YRR GHNE+DEPMFTQPLMY+ I++
Sbjct: 499 FHVNADDPEAVVYVCQIAAEWRSTFNKDVVIDLVSYRRFGHNEMDEPMFTQPLMYKLIRR 558
Query: 1482 TKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDF 1303
+ L+KY + ++ EGV Q +EE+ KY I E+AY +++ + R WLDSPW DF
Sbjct: 559 QEHVLKKYSDHLIAEGVVTLQEYEEEVAKYDKICEEAYASSKDEKILHIRHWLDSPWPDF 618
Query: 1302 FKKRDPLKLPS---TGXXXXXXXXXIGKFSQYP-EGFNLHRGLERTLKGRQQMLKDNSLD 1135
F K S TG S P E FN+H G+ R L+GR ++ +D
Sbjct: 619 FTAEGEPKSMSYAPTGLDEEILQHIGKAASSVPLEDFNIHHGVSRILRGRADLVAKRQVD 678
Query: 1134 WACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGE 955
WA E +AFGSLLK+GIHVRLSGQDV+RGTFSHRHHVLHDQ+VD++I P+N L Q
Sbjct: 679 WALAEYMAFGSLLKDGIHVRLSGQDVERGTFSHRHHVLHDQEVDKRICVPMNYLWPNQAP 738
Query: 954 YTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQ 775
YTVCNS LSEY VLGFELG++M PN+L++WEAQFGDF NTAQCIIDQFISSGQ+KW+R
Sbjct: 739 YTVCNSCLSEYGVLGFELGFAMASPNALILWEAQFGDFHNTAQCIIDQFISSGQAKWVRN 798
Query: 774 SGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI------DLEKIAFEGTFEAQQLHD 613
+G+V+LLPHG EGMGPEHSSARPERFLQM +D + DL + + FE QQL+D
Sbjct: 799 NGIVLLLPHGMEGMGPEHSSARPERFLQMSKDDPDHFPVRCGDLLSASLD--FEVQQLYD 856
Query: 612 TNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRV 433
NWI NC+TPAN H+LRRQV +PFRKP ++F+PKSLLRHP ARS +D +G+ F+R+
Sbjct: 857 CNWIAVNCSTPANYCHVLRRQVLLPFRKPLIIFTPKSLLRHPDARSSFDDLTTGTKFKRL 916
Query: 432 IPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQE 253
IP+ G Q+P VKRV+FC+GKVYYD+ RK E +VA+VR+EQ+SPFP+DLV+ E
Sbjct: 917 IPDEGPAGQDPARVKRVIFCSGKVYYDLAKERKDQKLEREVAIVRLEQISPFPFDLVRTE 976
Query: 252 CRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHM 73
KY AE++W QEEHKNMG + +V+PR ++L+ + + Y GR P+++PATG + TH+
Sbjct: 977 AEKYVDAELVWCQEEHKNMGYYDYVRPRFLTVLA-NRKPIWYVGREPAAAPATGTRSTHL 1035
Query: 72 QEQKEMMSKVFGV 34
E K + F +
Sbjct: 1036 TELKRFVETAFSL 1048
>gi|47228548|emb|CAG05368.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1005
Score = 1046 bits (2705), Expect = 0.0
Identities = 544/1003 (54%), Positives = 683/1003 (67%), Gaps = 46/1003 (4%)
Frame = -1
Query: 2946 EPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALG 2767
EPFLNG+SS YIE+MY AWL++P SVH SW+ YFRNV G
Sbjct: 48 EPFLNGTSSNYIEEMYLAWLENPKSVHKSWEVYFRNVNA--------------------G 87
Query: 2766 VSPAAAQVTTSS--APATRLDTNASVQS-----ISDHLKIQLLIRSYQTRGHNIADLDPL 2608
V P AA + SS P L T +Q ++DHL + LIR+YQ G I
Sbjct: 88 VPPGAAYQSPSSLGEPPQGLRTLVGIQPNIEELVTDHLAVYSLIRAYQ--GCTI------ 139
Query: 2607 GINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKS-LTLREILQRLKDIYC 2431
+E YGL E +D+ F LP TT+I +S L LREI+ RL+ YC
Sbjct: 140 ------------HWVEEGSYGLNESHMDKVFWLPKTTYIGGSESALPLREIIHRLETAYC 187
Query: 2430 TSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSE 2251
GVE+M +NNLEQ WIR+RFE P + +LS ++K+ L R+I+ST+FEEFL KKW SE
Sbjct: 188 QHIGVEFMFINNLEQCQWIRQRFETPGLMKLSLEEKRTLLNRVIKSTRFEEFLHKKWSSE 247
Query: 2250 KRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS- 2074
KRFGLEGCE LIPA+K +ID SS GV+S ++GMPHRGRLNVLANV + L IL QF
Sbjct: 248 KRFGLEGCESLIPALKTIIDESSKSGVESVIMGMPHRGRLNVLANVFHKELDQILCQFDP 307
Query: 2073 TLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYA 1894
LE ADEGSGDVKYHLG +R N S+K++ ++++ANPSHLEAVDPVV GK +AE FY
Sbjct: 308 KLEAADEGSGDVKYHLGTYQKRFNPVSKKDIMMSLMANPSHLEAVDPVVQGKTKAEQFYC 367
Query: 1893 GDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSS 1714
D + + M++LLHGDAAFAGQGVV ETF+L DLPSYTTHG IH+VVNNQIGFTTDPR +
Sbjct: 368 DDTEGKKVMSLLLHGDAAFAGQGVVYETFHLSDLPSYTTHGTIHVVVNNQIGFTTDPRVA 427
Query: 1713 RSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNE 1534
RSSP+ TDV RVV PIFHVN DD EAV++VC VA +WR TF KDV+VDLVCYRR+GHNE
Sbjct: 428 RSSPHPTDVARVVNAPIFHVNADDAEAVIYVCKVATEWRNTFHKDVVVDLVCYRRNGHNE 487
Query: 1533 LDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQK 1354
+DEPMFTQPLMY++I++ K L K EK +++GV +Q KE++ +Y I EDA+ ++
Sbjct: 488 MDEPMFTQPLMYKKIRKQKGVLTKCAEKFISDGVITQQEYKEKVAQYDKICEDAHNRSKD 547
Query: 1353 VTYVRNRDWLDSPWDDFFK---KRDPLKLPSTGXXXXXXXXXIGKFSQYP-EGFNLHRGL 1186
+ + N+ WL SPW +FFK + + STG S P E +H GL
Sbjct: 548 MKVLENKHWLSSPWPEFFKLDGEPKTMSCDSTGIPEEQLRHIGNVASSVPLEKLTIHGGL 607
Query: 1185 ERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKV 1006
R LK R M+ DWA GE +AFGSLL++GIHVRLSGQDV+RGTFSHRHHVLHDQ +
Sbjct: 608 TRILKARADMVNKRVCDWALGEYMAFGSLLQDGIHVRLSGQDVERGTFSHRHHVLHDQNI 667
Query: 1005 DQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQ 826
D++ Y PLN +S GQ YTVCNSSLSEY VLGFELG++M PN+LV+WEAQFGDF NTAQ
Sbjct: 668 DKENYIPLNHISHGQARYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQ 727
Query: 825 CIIDQFISSGQSKWIRQSGLVMLLPHGYEGM----------------------------- 733
CIIDQFISSGQ+KW+RQSG+V+LLPHG EGM
Sbjct: 728 CIIDQFISSGQAKWVRQSGIVLLLPHGMEGMVKHKTPSTPFRLTSSQPVNMSLLPFCPIF 787
Query: 732 ----GPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYH 565
GPEHSSARPERFLQMCN+D ++ E F +QL D NWIV NC+TPA+ +H
Sbjct: 788 CPSQGPEHSSARPERFLQMCNDDPDVFPE---VTEDFAVRQLCDCNWIVVNCSTPASYFH 844
Query: 564 LLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKR 385
LRRQ+ +PFRKP +VF+PKSLLR ARS +D G++F+R+IP+ G S +P +VKR
Sbjct: 845 ALRRQILLPFRKPLIVFTPKSLLR--QARSSFDDMLPGTHFRRIIPDDGPASVHPQEVKR 902
Query: 384 VVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEH 205
V+FCTGK+YY ++ R+ G ++ VA+VR+EQLSPFP+DLV+ E +Y AE++W QEEH
Sbjct: 903 VIFCTGKIYYKLIQEREGRGLDDTVAVVRLEQLSPFPFDLVKAEIDQYTNAELVWCQEEH 962
Query: 204 KNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTH 76
KN G +++++PR+ S S R +YAGR P+++PATGNK TH
Sbjct: 963 KNQGYYNYIKPRL-SASSGHTRPVRYAGREPAAAPATGNKRTH 1004
>gi|283950|pir||A38234 oxoglutarate dehydrogenase (lipoamide) (EC
1.2.4.2) precursor - human
Length = 1003
Score = 1044 bits (2700), Expect = 0.0
Identities = 528/982 (53%), Positives = 674/982 (67%), Gaps = 19/982 (1%)
Frame = -1
Query: 2964 AAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXA 2785
+A V EPFL+G+SS Y+E+MY AWL++P SVH SWD +FRN
Sbjct: 41 SAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNAGAPPALLPESPSLSR 100
Query: 2784 YAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLG 2605
G+L A + + +L + DHL +Q LIR+YQ RGH++A LDPLG
Sbjct: 101 --GSLAAVAHAQSLVEAQPNVDKL--------VEDHLAVQSLIRAYQIRGHHVAQLDPLG 150
Query: 2604 INSADLDDTIPP------ELELSFYGLGERDLDREFLLPPTTFISEKKS-LTLREILQRL 2446
I ADLD ++ P + L R PPTTFI ++S L LREI++RL
Sbjct: 151 ILDADLDSSVAPLTLSHPQTNLGSMAWMSLTSTRSSTCPPTTFIGGQESALPLREIIRRL 210
Query: 2445 KDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAK 2266
+ YC GVE+M +N+LEQ WIR++FE P + + ++++K+ L RL+RST+FEEFL +
Sbjct: 211 EMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQR 270
Query: 2265 KWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATIL 2086
KW SEKRFGLEGCEVLIPA+K +ID SS GVD ++GMPHRGRLNVLANV R+ L I
Sbjct: 271 KWSSEKRFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIF 330
Query: 2085 SQF-STLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVA-----NPSHLEAVDPVVM 1924
QF S LE ADEG + G ++ Q Q + + NPSHLEA DPVVM
Sbjct: 331 CQFDSKLEAADEGLRRCEVPPG----HVSPQDQSCHRPGTLPCPWWPNPSHLEAADPVVM 386
Query: 1923 GKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQ 1744
GK +AE FY GD + + M+ILLHGDAAFAGQG+V ETF+L DLPSYTTHG +H+VVNNQ
Sbjct: 387 GKTKAEQFYCGDTEGKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQ 446
Query: 1743 IGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDL 1564
IGFTTDPR +RSSPY TDV RVV PIFHVN DDPEAVM+VC VAA+WR TF KDV+VDL
Sbjct: 447 IGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDL 506
Query: 1563 VCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSI 1384
VCYRR+GHNE+DEPMFTQPLMY++I++ K L+KY E ++++GV N+ +EE++KY I
Sbjct: 507 VCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKI 566
Query: 1383 LEDAYENAQKVTYVRNRDWLDSPWDDFFK---KRDPLKLPSTGXXXXXXXXXIGKFSQYP 1213
E+A+ ++ + + WLDSPW FF + + PSTG S P
Sbjct: 567 CEEAFARSKDEKILHIKHWLDSPWPGFFTLDGQPRSMSCPSTGLTEDILTHIGNVASSVP 626
Query: 1212 -EGFNLHRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSH 1036
E F +H GL R LK R +M+K+ ++DWA E +AFGSLLKEGIH+RLSGQDV+RGTFSH
Sbjct: 627 VENFTIHGGLSRILKTRGEMVKNRTVDWALAEYMAFGSLLKEGIHIRLSGQDVERGTFSH 686
Query: 1035 RHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEA 856
RHHVLHDQ VD++ P+N L Q YTVCNSSLSEY VLGF G M PN+LV+WEA
Sbjct: 687 RHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFGAGLRMASPNALVLWEA 746
Query: 855 QFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNED 676
QFGDF NTAQCIIDQFI GQ+KW+RQ+G+V+LLP G EGMGPEHSS P FLQMCN+D
Sbjct: 747 QFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPLGMEGMGPEHSSGPPRAFLQMCNDD 806
Query: 675 DEI--DLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKS 502
++ DL+ E F+ QL+D NW+V NC+TP N +H+LRRQ+ +PFRKP ++F+PKS
Sbjct: 807 PDVLPDLK----EANFDINQLYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKS 862
Query: 501 LLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGK 322
LLRHP ARS ++ G++FQRVIPE G +QNP +VKR++FCTGKVYYD+ RK
Sbjct: 863 LLRHPEARSSFDEMLPGTHFQRVIPEDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDM 922
Query: 321 ENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDG 142
VA+ R+E +SPFP+DL+ +E +KY AE+ W QEEHKN G + +V+PR+ + +S
Sbjct: 923 VGQVAITRIEHVSPFPFDLLLKEVQKYPNAELAWCQEEHKNQGYYDYVKPRLRTTIS-RA 981
Query: 141 RATKYAGRLPSSSPATGNKFTH 76
+ YAGR P+++P TGNK TH
Sbjct: 982 KPVWYAGRDPAAAPRTGNKKTH 1003
>gi|24655383|ref|NP_728639.1| CG32316-PD [Drosophila melanogaster]
gi|28574264|ref|NP_788454.1| CG32316-PF [Drosophila melanogaster]
gi|23092794|gb|AAN11492.1| CG32316-PD [Drosophila melanogaster]
gi|28380424|gb|AAO41213.1| CG32316-PF [Drosophila melanogaster]
Length = 1238
Score = 1031 bits (2667), Expect = 0.0
Identities = 539/1043 (51%), Positives = 693/1043 (65%), Gaps = 27/1043 (2%)
Frame = -1
Query: 3069 CRLASPSRINAIRNASSGKSHISASTLVQHRNQSVAAAVKH------EPFLNGSSSIYIE 2908
CRL S +RI R+ + G L + +++ + + F NG S+ YIE
Sbjct: 4 CRLRSLARIR--RSLTLGLRGTDQHVLARQALRTIQTTSQRRGVHDLDSFANGCSAAYIE 61
Query: 2907 QMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAY----AGALGVSPAAAQVT 2740
+Y W ++PSSV SW+ F + + Y + V + + T
Sbjct: 62 GLYNKWKRNPSSVDESWNELFSSNDWSSPKRSPLQVSHSRKYRRPPVERIAVKARSGERT 121
Query: 2739 TSS-APATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGI----NSADLDDT- 2578
S A A + ++I DH IQ +IR+YQ+RGH ADLDPLGI +D T
Sbjct: 122 ASGGASAAPAAPPSDWKNIDDHHVIQAIIRAYQSRGHLAADLDPLGIVGPKKRTSVDGTQ 181
Query: 2577 --IPPELELSFYGLGERDLDREFLLPPTTFIS-EKKSLTLREILQRLKDIYCTSTGVEYM 2407
E+ + DL+ F LP +T I +++ L+L+EIL RL+ IYC GVEYM
Sbjct: 182 RHAAREVLRQHFSYIFNDLNTVFKLPSSTMIGGDQEFLSLKEILDRLERIYCGHIGVEYM 241
Query: 2406 HLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGC 2227
+ +L + +W+R RFE P +L+ ++KK++ +RL RST FE FLAKK+ SEKRFGLEGC
Sbjct: 242 QITSLTKTNWLRDRFEKPGGLDLTKEEKKLILERLTRSTGFENFLAKKFSSEKRFGLEGC 301
Query: 2226 EVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGS 2047
+++IPA+K+V+D ++ GV+S +IGM HRGRLNVLAN+CR+P++ ILSQF L+ D GS
Sbjct: 302 DIMIPAIKEVVDRATDHGVESILIGMAHRGRLNVLANICRKPISDILSQFHGLQATDSGS 361
Query: 2046 GDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTM 1867
GDVKYHLGV ERLNRQ+ + V+I VVANPSHLE V+PV++GK RAE F GD M
Sbjct: 362 GDVKYHLGVFQERLNRQTNRMVRITVVANPSHLEHVNPVLLGKARAEMFQRGDTCGSTVM 421
Query: 1866 AILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDV 1687
I++HGDA+F+GQGVV E+ +L DLP+YTT+G IHIV NNQ+GFTTDPR SRSS YCTDV
Sbjct: 422 PIIIHGDASFSGQGVVYESMHLSDLPNYTTYGTIHIVSNNQVGFTTDPRFSRSSRYCTDV 481
Query: 1686 GRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQP 1507
+VV PI HVN DDPEA + +A D+R FKKDV++D+V YRR+GHNE DEPMFTQP
Sbjct: 482 AKVVNAPILHVNADDPEACIQCARIAIDYRTRFKKDVVIDIVGYRRNGHNEADEPMFTQP 541
Query: 1506 LMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDW 1327
LMYQRIK+ K L+ Y +K++ EGV + K ++ Y I EDA+ ++ + ++ W
Sbjct: 542 LMYQRIKKLKPCLQLYADKLIKEGVVTDSEFKAMVSSYEKICEDAWAKSKTIKTIKYSSW 601
Query: 1326 LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYP---EGFNLHRGLERTLKGRQQM 1156
+DSPW FF+ RD LKL TG FS P F H+G+ R L R QM
Sbjct: 602 IDSPWPGFFEGRDRLKLCPTGISTDTLKTIGNMFSTPPPPEHKFETHKGILRILAQRTQM 661
Query: 1155 LKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLND 976
++D DW+ GEA AFGSLLKEGIHVRLSGQDV+RGTFSHRHHVLH Q D+ +YN L+
Sbjct: 662 VQDKVADWSLGEAFAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHHQSEDKVVYNSLDH 721
Query: 975 LSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSG 796
L Q Y+V NSSLSE AVLGFE GYSM PN+LV+WE QFGDF NTAQCIID FI+SG
Sbjct: 722 LYPDQAPYSVSNSSLSECAVLGFEHGYSMASPNALVMWEGQFGDFCNTAQCIIDTFIASG 781
Query: 795 QSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLH 616
++KW+RQSG+VMLLPH EGMGPEHSS R ERFLQM DD+ D+ + F A+QL
Sbjct: 782 ETKWVRQSGVVMLLPHSMEGMGPEHSSGRIERFLQM--SDDDPDVYPDTCDADFVARQLM 839
Query: 615 DTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQR 436
+ NWIV N +TPAN++H LRRQV M FRKP + FSPKSLLRHP+ARSP +DF S FQR
Sbjct: 840 NVNWIVTNLSTPANLFHCLRRQVKMGFRKPLINFSPKSLLRHPLARSPFKDFNECSCFQR 899
Query: 435 VIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQ 256
+IP+ G + P V+++VFC+GKVYYD+V R + VALVRVEQL PFPYDL+ Q
Sbjct: 900 IIPDKGPAGKQPDCVQKLVFCSGKVYYDLVKERDDHEQVETVALVRVEQLCPFPYDLISQ 959
Query: 255 ECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLL---SIDGRATKYAGRLPSSSPATGNK 85
+ Y AE+LWAQEEHKNMGAWS+VQPR ++ L + R Y GR PS+SPATGNK
Sbjct: 960 QLELYPKAELLWAQEEHKNMGAWSYVQPRFDTALLKNENESRCVSYHGRPPSASPATGNK 1019
Query: 84 FTHMQEQKEMMSKVFG--VPKSK 22
H E K +++ +FG P++K
Sbjct: 1020 VQHYNEYKALITSIFGELTPENK 1042
>gi|24655380|ref|NP_728638.1| CG32316-PB [Drosophila melanogaster]
gi|28574266|ref|NP_788453.1| CG32316-PG [Drosophila melanogaster]
gi|16648244|gb|AAL25387.1| GH27234p [Drosophila melanogaster]
gi|23092792|gb|AAF47520.2| CG32316-PG [Drosophila melanogaster]
gi|23092793|gb|AAF47519.2| CG32316-PB [Drosophila melanogaster]
Length = 1282
Score = 1019 bits (2634), Expect = 0.0
Identities = 539/1065 (50%), Positives = 693/1065 (64%), Gaps = 49/1065 (4%)
Frame = -1
Query: 3069 CRLASPSRINAIRNASSGKSHISASTLVQHRNQSVAAAVKH------EPFLNGSSSIYIE 2908
CRL S +RI R+ + G L + +++ + + F NG S+ YIE
Sbjct: 4 CRLRSLARIR--RSLTLGLRGTDQHVLARQALRTIQTTSQRRGVHDLDSFANGCSAAYIE 61
Query: 2907 QMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAY----AGALGVSPAAAQVT 2740
+Y W ++PSSV SW+ F + + Y + V + + T
Sbjct: 62 GLYNKWKRNPSSVDESWNELFSSNDWSSPKRSPLQVSHSRKYRRPPVERIAVKARSGERT 121
Query: 2739 TSS-APATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGI----NSADLDDT- 2578
S A A + ++I DH IQ +IR+YQ+RGH ADLDPLGI +D T
Sbjct: 122 ASGGASAAPAAPPSDWKNIDDHHVIQAIIRAYQSRGHLAADLDPLGIVGPKKRTSVDGTQ 181
Query: 2577 --IPPELELSFYGLGERDLDREFLLPPTTFIS-EKKSLTLREILQRLKDIYCTSTGVEYM 2407
E+ + DL+ F LP +T I +++ L+L+EIL RL+ IYC GVEYM
Sbjct: 182 RHAAREVLRQHFSYIFNDLNTVFKLPSSTMIGGDQEFLSLKEILDRLERIYCGHIGVEYM 241
Query: 2406 HLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGC 2227
+ +L + +W+R RFE P +L+ ++KK++ +RL RST FE FLAKK+ SEKRFGLEGC
Sbjct: 242 QITSLTKTNWLRDRFEKPGGLDLTKEEKKLILERLTRSTGFENFLAKKFSSEKRFGLEGC 301
Query: 2226 EVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGS 2047
+++IPA+K+V+D ++ GV+S +IGM HRGRLNVLAN+CR+P++ ILSQF L+ D GS
Sbjct: 302 DIMIPAIKEVVDRATDHGVESILIGMAHRGRLNVLANICRKPISDILSQFHGLQATDSGS 361
Query: 2046 GDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTM 1867
GDVKYHLGV ERLNRQ+ + V+I VVANPSHLE V+PV++GK RAE F GD M
Sbjct: 362 GDVKYHLGVFQERLNRQTNRMVRITVVANPSHLEHVNPVLLGKARAEMFQRGDTCGSTVM 421
Query: 1866 AILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDV 1687
I++HGDA+F+GQGVV E+ +L DLP+YTT+G IHIV NNQ+GFTTDPR SRSS YCTDV
Sbjct: 422 PIIIHGDASFSGQGVVYESMHLSDLPNYTTYGTIHIVSNNQVGFTTDPRFSRSSRYCTDV 481
Query: 1686 GRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQP 1507
+VV PI HVN DDPEA + +A D+R FKKDV++D+V YRR+GHNE DEPMFTQP
Sbjct: 482 AKVVNAPILHVNADDPEACIQCARIAIDYRTRFKKDVVIDIVGYRRNGHNEADEPMFTQP 541
Query: 1506 LMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDW 1327
LMYQRIK+ K L+ Y +K++ EGV + K ++ Y I EDA+ ++ + ++ W
Sbjct: 542 LMYQRIKKLKPCLQLYADKLIKEGVVTDSEFKAMVSSYEKICEDAWAKSKTIKTIKYSSW 601
Query: 1326 LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYP---EGFNLHRGLERTLKGRQQM 1156
+DSPW FF+ RD LKL TG FS P F H+G+ R L R QM
Sbjct: 602 IDSPWPGFFEGRDRLKLCPTGISTDTLKTIGNMFSTPPPPEHKFETHKGILRILAQRTQM 661
Query: 1155 LKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLND 976
++D DW+ GEA AFGSLLKEGIHVRLSGQDV+RGTFSHRHHVLH Q D+ +YN L+
Sbjct: 662 VQDKVADWSLGEAFAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHHQSEDKVVYNSLDH 721
Query: 975 LSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSG 796
L Q Y+V NSSLSE AVLGFE GYSM PN+LV+WE QFGDF NTAQCIID FI+SG
Sbjct: 722 LYPDQAPYSVSNSSLSECAVLGFEHGYSMASPNALVMWEGQFGDFCNTAQCIIDTFIASG 781
Query: 795 QSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLH 616
++KW+RQSG+VMLLPH EGMGPEHSS R ERFLQM DD+ D+ + F A+QL
Sbjct: 782 ETKWVRQSGVVMLLPHSMEGMGPEHSSGRIERFLQM--SDDDPDVYPDTCDADFVARQLM 839
Query: 615 DTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQR 436
+ NWIV N +TPAN++H LRRQV M FRKP + FSPKSLLRHP+ARSP +DF S FQR
Sbjct: 840 NVNWIVTNLSTPANLFHCLRRQVKMGFRKPLINFSPKSLLRHPLARSPFKDFNECSCFQR 899
Query: 435 VIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVE------------ 292
+IP+ G + P V+++VFC+GKVYYD+V R + VALVRVE
Sbjct: 900 IIPDKGPAGKQPDCVQKLVFCSGKVYYDLVKERDDHEQVETVALVRVEQVRRLPTRHLFL 959
Query: 291 ----------QLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLL---S 151
QL PFPYDL+ Q+ Y AE+LWAQEEHKNMGAWS+VQPR ++ L
Sbjct: 960 FMITMIGRILQLCPFPYDLISQQLELYPKAELLWAQEEHKNMGAWSYVQPRFDTALLKNE 1019
Query: 150 IDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFG--VPKSK 22
+ R Y GR PS+SPATGNK H E K +++ +FG P++K
Sbjct: 1020 NESRCVSYHGRPPSASPATGNKVQHYNEYKALITSIFGELTPENK 1064
>gi|49096496|ref|XP_409708.1| hypothetical protein AN5571.2
[Aspergillus nidulans FGSC A4]
gi|40743086|gb|EAA62276.1| hypothetical protein AN5571.2 [Aspergillus
nidulans FGSC A4]
Length = 1048
Score = 926 bits (2393), Expect = 0.0
Identities = 504/1054 (47%), Positives = 677/1054 (63%), Gaps = 28/1054 (2%)
Frame = -1
Query: 3090 MHRASLICRLASPSRINAIRN---ASSGKSHISASTLVQHRNQSVAAAVKHEPFLNGSSS 2920
M AS + R S S+ A GK ++S + VAA+ + FL+G+++
Sbjct: 23 MSLASTVRRADSSSKFGLATRRPLALVGKRFYASSA----EDSGVAAS---DSFLSGNTA 75
Query: 2919 IYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVT 2740
YI++MY AW +DPSSVH SW YFRN+E + + P
Sbjct: 76 NYIDEMYVAWRKDPSSVHISWQTYFRNMEEGKMPISQA-------FQPPPTLVPTPTGGV 128
Query: 2739 TSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGIN--SADLDDTIPPE 2566
P L + ++ HLK+QLL+R+YQ RGH+ A +DPLGI + + P E
Sbjct: 129 HQEMPGAGLGLSQGTD-VTKHLKVQLLVRAYQARGHHKAKIDPLGIRGEAEAFGYSKPKE 187
Query: 2565 LELSFYGLGERDLDREFLLPP---TTFISE-KKSLTLREILQRLKDIYCTSTGVEYMHLN 2398
LEL YG ERDLD EF L P F +E +K ++LREI+ + IYC S GVEY+H+
Sbjct: 188 LELDHYGFTERDLDEEFDLGPGILPRFATEGRKKMSLREIIAACEKIYCGSYGVEYIHIP 247
Query: 2397 NLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVL 2218
+ + DWIR RFE P + S D K+ + RLI S+ FE FLA K+P++KRFGLEGCE L
Sbjct: 248 DRKPCDWIRDRFEVPEPYKYSVDDKRRILDRLIWSSSFEAFLATKFPNDKRFGLEGCETL 307
Query: 2217 IPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEPADEGSGD 2041
+P MK +ID S G+ VIGMPHRGRLNVL+NV R+P +I S+F+ + EP+DEGSGD
Sbjct: 308 VPGMKALIDRSVDYGIKDIVIGMPHRGRLNVLSNVVRKPNESIFSEFAGSAEPSDEGSGD 367
Query: 2040 VKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEK-CDRTMA 1864
VKYHLG+ ER S K V++++VANPSHLEA DPVV+GK RA Y DEK D M
Sbjct: 368 VKYHLGMNFERPT-PSGKRVQLSLVANPSHLEAEDPVVLGKTRAIQHYNNDEKNFDSAMG 426
Query: 1863 ILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVG 1684
+LLHGDAAFA QG+V ET LP+Y+T G IHIVVNNQIGFTTDPR +RS+PYC+D+
Sbjct: 427 VLLHGDAAFAAQGIVYETMGFHSLPAYSTGGTIHIVVNNQIGFTTDPRFARSTPYCSDIA 486
Query: 1683 RVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPL 1504
+ + P+FHVN DD EAV +VC VAADWR FK+DV++D+VCYR+ GHNE D+P FTQPL
Sbjct: 487 KSIDAPVFHVNADDVEAVNYVCQVAADWRAEFKRDVVIDIVCYRKQGHNETDQPSFTQPL 546
Query: 1503 MYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWL 1324
MY+R+ + K L+ Y EK+++EG ++ + E +L D+++ + K ++WL
Sbjct: 547 MYKRVAEKKLQLDMYVEKLISEGTFTKEDIDEHKKWVWGMLNDSFDRS-KDYQPTGKEWL 605
Query: 1323 DSPWDDFFKKRDPLKLPS-------TGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGR 1165
S W+ F + P +L + T K S PEGF LHR L+R L R
Sbjct: 606 TSAWNGF---KTPKELATEVLPHLPTAVEPPILKNVADKISGAPEGFTLHRNLKRILGNR 662
Query: 1164 QQMLKD-NSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYN 988
++ +++ ++DWA EALAFGSL+ EG HVR+SGQDV+RGTFS RH VLHDQ+ + Y
Sbjct: 663 KKTVEEGKNIDWATAEALAFGSLVSEGYHVRVSGQDVERGTFSQRHAVLHDQET-EATYT 721
Query: 987 PLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQF 808
PL +S+ QG + + NSSLSE+ LGFE GYS+ PN+LV+WEAQFGDF+N AQCIIDQF
Sbjct: 722 PLQHISKDQGSFVISNSSLSEFGALGFEYGYSLTSPNALVMWEAQFGDFANNAQCIIDQF 781
Query: 807 ISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEA 628
I+SG+SKW+++SGLV+ LPHGY+G GPEHSS R ER+LQ+CNE+ + + +
Sbjct: 782 IASGESKWLQRSGLVLSLPHGYDGQGPEHSSGRMERYLQLCNEEPRVFPSQDKLD----- 836
Query: 627 QQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGS 448
+Q D N VA T+PAN++HLLRRQ+ FRKP V+F KSLLRHP+ARS +E+F S
Sbjct: 837 RQHQDCNMQVAYMTSPANLFHLLRRQIHRQFRKPLVIFFSKSLLRHPLARSSIEEFTGDS 896
Query: 447 NFQRVIPET--GAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKEN--DVALVRVEQLSP 280
+FQ +IP+ G P ++RV+ C+G+VY A KH N + A+ RVEQL P
Sbjct: 897 HFQWIIPDPAHGTAIDEPEKIERVILCSGQVY---AALTKHREANNIRNTAITRVEQLHP 953
Query: 279 FPYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLS----IDGRATKYAGRL 115
FP+ +++ Y A I+WAQEE N G+WS+VQPRI +LL+ + R YAGR
Sbjct: 954 FPWAQLKENLDSYPNARNIVWAQEEPLNAGSWSYVQPRIETLLNETEHHNRRHVMYAGRP 1013
Query: 114 PSSSPATGNKFTHMQEQKEMMSKVFGVPKSKLEG 13
PS+S ATG K H++E++EM+ + F V + +L+G
Sbjct: 1014 PSASVATGLKSVHVKEEQEMLEEAFSVHQERLKG 1047
>gi|50259854|gb|EAL22522.1| hypothetical protein CNBB4000
[Cryptococcus neoformans var. neoformans B-3501A]
Length = 1055
Score = 908 bits (2347), Expect = 0.0
Identities = 488/1039 (46%), Positives = 660/1039 (62%), Gaps = 22/1039 (2%)
Frame = -1
Query: 3081 ASLICRLASPSRINAIRNASSGKSHISASTLVQHRNQSVAAAV-----KHEPFLNGSSSI 2917
A+++ + RI + A ++ +S S + +H + AA K++ F NG ++
Sbjct: 34 AAMLRSIPKHIRIPSRSTAQPARAILSLSAVQRHTQKRSYAAEAVAPSKNDAFANGGNAY 93
Query: 2916 YIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVTT 2737
Y E+MY W QDP SVH SW YF ++ + GV A
Sbjct: 94 YTEEMYRLWKQDPKSVHVSWQTYFSGLDKGLPSAHA--------FTPPPGVLSGAVPTPA 145
Query: 2736 SSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELEL 2557
+P ++ + V +D+LK+QLLIR+YQ RGH+IA+LDPL I+ ADLD +PPEL+L
Sbjct: 146 GGSPKLSVEGSGDV---TDYLKVQLLIRAYQVRGHHIANLDPLRISGADLDGRVPPELKL 202
Query: 2556 SFYGLGERDLDREF-----LLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNL 2392
+YG E D+ +EF +LP + ++TL +I+ LK +YCT G +Y+H+ +
Sbjct: 203 DYYGWTEADMTKEFRLGDGILPRFMGQVKDDTMTLGQIIDELKQMYCTHVGCQYVHIPDR 262
Query: 2391 EQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIP 2212
Q DWIR R E P S ++K+++ RL+ S FE+F+A K+P+EKRFGLEGCE LIP
Sbjct: 263 GQCDWIRERVEIPTQWNYSTEEKRMILDRLMWSELFEKFIASKYPNEKRFGLEGCESLIP 322
Query: 2211 AMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADE-GSGDVK 2035
MK +ID S GV S V+GMPHRGRLNVL NV R+P+ IL++F E AD+ G GDVK
Sbjct: 323 GMKALIDRSVDAGVKSIVLGMPHRGRLNVLGNVIRKPIEAILNEFKGNEDADDTGGGDVK 382
Query: 2034 YHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDE-KCDRTMAIL 1858
YHLG R S K V +++VANPSHLEA DPVV+GK RA + GDE M +L
Sbjct: 383 YHLGANYIRPT-PSGKKVSLSLVANPSHLEAEDPVVLGKTRAIQHFEGDEGDGSSAMGVL 441
Query: 1857 LHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRV 1678
LHGDAAFAGQGVV ET + +LP+Y T G +H++VNNQIGFTTDPR +RS+PY +D+ +
Sbjct: 442 LHGDAAFAGQGVVYETMGMQNLPNYGTGGTVHLIVNNQIGFTTDPRFARSTPYPSDIAKS 501
Query: 1677 VGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMY 1498
+ PIFHVN DD EAV +VC +AADWR TFKKDV++D+VCYRR+GHNE D+P FTQP MY
Sbjct: 502 IDAPIFHVNSDDVEAVNYVCTLAADWRATFKKDVVIDIVCYRRYGHNETDQPSFTQPKMY 561
Query: 1497 QRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDS 1318
+ I++ T L Y +K++ EG E+ + E +LE AY+ ++ R+WL S
Sbjct: 562 KAIQKQPTVLSIYTDKLIKEGTFTEKEIDEHRQWVWGMLEKAYDGSRDYK-PSPREWLSS 620
Query: 1317 PWDDFFKKRDPLK--LPS--TGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGR-QQML 1153
W+ F ++ + LP TG S +PEGF+ H+ L R + R + +
Sbjct: 621 SWEGFPSPKELAEEVLPQHHTGASEDALKRVGQIISSFPEGFHPHKNLARIIGNRGKTVA 680
Query: 1152 KDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDL 973
+ ++DW+ EALAFG+L EG HVR+SGQDV+RGTFS RH V+HDQK +Q + L L
Sbjct: 681 EGKNIDWSTAEALAFGTLCLEGTHVRISGQDVERGTFSQRHAVVHDQKTEQ-THIALKHL 739
Query: 972 SEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQ 793
QG +TV NS LSE+ LGFELGYS+V PNSL IWEAQFGDF+N AQCIIDQFI++G+
Sbjct: 740 DADQGSFTVTNSHLSEFGTLGFELGYSLVSPNSLTIWEAQFGDFANNAQCIIDQFIAAGE 799
Query: 792 SKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHD 613
KW++++GLV+ LPHGY+G GPEHSS R ERFLQ+C+++ + E +Q D
Sbjct: 800 RKWLQRTGLVLSLPHGYDGQGPEHSSGRIERFLQLCDDEPRVYPSPEKLE-----RQHQD 854
Query: 612 TNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRV 433
N V TTPAN +H+LRRQ FRKP +VF KSLLRHP+ARS +E+ S FQR
Sbjct: 855 CNMQVVYPTTPANYFHVLRRQNKRDFRKPLIVFFSKSLLRHPLARSSLEEMSGDSKFQRY 914
Query: 432 IPETGAPS-QNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQ 256
IPE S P ++R + CTG+VY+ ++ R+ G NDVA+ R+EQLSP PYD +
Sbjct: 915 IPEPHPESLVEPEKIRRHILCTGQVYFQLLKEREERG-INDVAISRIEQLSPLPYDRLTP 973
Query: 255 ECRKYQGAEILWAQEEHKNMGAWSFVQPR-INSLLSIDGRATK---YAGRLPSSSPATGN 88
KY A+++WAQEE N GAW++VQPR I +L + +K YAGR PSSS ATG+
Sbjct: 974 HLDKYPNADLVWAQEEPLNNGAWTYVQPRLITALQETEHHKSKIPFYAGRKPSSSVATGS 1033
Query: 87 KFTHMQEQKEMMSKVFGVP 31
K+ H +E EM++++ P
Sbjct: 1034 KYAHKKE-IEMINEMAFAP 1051
>gi|32409599|ref|XP_325280.1| probable oxoglutarate dehydrogenase
precursor [MIPS] [Neurospora crassa]
gi|28924920|gb|EAA34012.1| probable oxoglutarate dehydrogenase
precursor [MIPS] [Neurospora crassa]
Length = 1194
Score = 906 bits (2341), Expect = 0.0
Identities = 477/1028 (46%), Positives = 670/1028 (64%), Gaps = 26/1028 (2%)
Frame = -1
Query: 3018 GKSHISASTLVQHRNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRN 2839
G+ ++ S +H + + ++ FL+GS++ YI++MY W QDP SVH SW YF+N
Sbjct: 186 GRRPLAVSQQRRHESALHSPPDPNDNFLSGSAANYIDEMYLQWKQDPKSVHVSWQVYFKN 245
Query: 2838 VEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLL 2659
+E GA V P A + + A+V ++HLK+QLL
Sbjct: 246 MESGNMPISQAFQPPPSLVPGAANVVPGLA-----AGAGVGIGEGANV---TNHLKVQLL 297
Query: 2658 IRSYQTRGHNIADLDPLGIN----SADLDDTIPPELELSFYGLGERDLDREFLLPP---T 2500
+R+YQ RGH+ A++DPLGI S + P EL +YG E+DLD E+ L P
Sbjct: 298 VRAYQARGHHKANIDPLGIRNTPASKGFGNIRPKELTPEYYGFTEKDLDTEYSLGPGILP 357
Query: 2499 TFISE-KKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQK 2323
F + ++ +TLREI+ + IYC S GVE++H+ + E+ DW+R R E P+ + S D+K
Sbjct: 358 RFARDGREKMTLREIIDACEKIYCGSYGVEFIHIPDREKCDWLRERLEIPQPFKYSIDEK 417
Query: 2322 KVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPH 2143
+ + RLI S+ FE FLA K+P++KRFGLEGCE L+P MK +ID S GV VIGMPH
Sbjct: 418 RRILDRLIWSSSFESFLATKYPNDKRFGLEGCETLVPGMKALIDRSVDYGVKDIVIGMPH 477
Query: 2142 RGRLNVLANVCRQPLATILSQFSTLEPADE-GSGDVKYHLGVCIERLNRQSQKNVKIAVV 1966
RGRLNVL+NV R+P I S+F+ + ADE GSGDVKYHLG+ ER S K V++++V
Sbjct: 478 RGRLNVLSNVVRKPNEAIFSEFAGMAGADEEGSGDVKYHLGMNFERPT-PSGKRVQLSLV 536
Query: 1965 ANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRT-MAILLHGDAAFAGQGVVLETFNLDDLP 1789
ANPSHLEA DPVV+GKVRA Y DE ++ M +LLHGDAA AGQG+V E +LP
Sbjct: 537 ANPSHLEAEDPVVLGKVRAIQHYNNDESDHKSAMGVLLHGDAAIAGQGIVYECLGFHNLP 596
Query: 1788 SYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVA 1609
+++T G IH+VVNNQIGFTTDPR +RS+ YCTD+ + + P+FHVN DD EAV VC +A
Sbjct: 597 AFSTGGTIHLVVNNQIGFTTDPRFARSTAYCTDIAKAIDAPVFHVNADDVEAVNFVCQLA 656
Query: 1608 ADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVA 1429
+DWR FK+DVI+DLVCYR+HGHNE D+P FTQPLMY+RI + ++ Y +++L EG
Sbjct: 657 SDWRAEFKQDVIIDLVCYRKHGHNETDQPAFTQPLMYKRISEKSPQIDIYVDQLLKEGTF 716
Query: 1428 NEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPS------- 1270
++ ++E +LE+++ + K +++W S W++F + P +L S
Sbjct: 717 TKEDIEEHKQWVWGMLEESFSKS-KDYQPTSKEWTTSAWNNF---KSPKELASEVLPHMP 772
Query: 1269 TGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGR-QQMLKDNSLDWACGEALAFGSLLK 1093
T PEGF+ HR L+R L R + +++ +DWA EALAFG+L+K
Sbjct: 773 TAVDKPTLEHIGTVIGSTPEGFHAHRNLKRILTNRTKSVVEGKGIDWATAEALAFGTLVK 832
Query: 1092 EGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVL 913
EG HVR++GQDV+RGTFS RH V HDQ+ + Y PL +SE Q + + NSSLSEY +L
Sbjct: 833 EGHHVRITGQDVERGTFSQRHAVFHDQETED-TYIPLQHISEDQAPFVISNSSLSEYGIL 891
Query: 912 GFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGM 733
GFE GYS+ DPN +WEAQFGDF+NTAQ IIDQF++SG+SKW++++GLVM LPHGY+G
Sbjct: 892 GFEYGYSLQDPNGFNMWEAQFGDFANTAQVIIDQFLASGESKWMQRTGLVMSLPHGYDGQ 951
Query: 732 GPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRR 553
GPEHSSAR ERFL +CNED I E +Q D N +A T+PAN++H+LRR
Sbjct: 952 GPEHSSARMERFLSLCNEDPRIYPSPEKLE-----RQHQDCNMQIAYMTSPANLFHILRR 1006
Query: 552 QVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPS---QNPPDVKRV 382
Q+ FRKP V+F K+LLRHP+ARS +E+F ++F+ ++P++ + + P +++RV
Sbjct: 1007 QLKRQFRKPLVIFFSKALLRHPVARSDIEEFTDDAHFRWILPDSAHQTGEIKAPEEIERV 1066
Query: 381 VFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAE-ILWAQEEH 205
+ CTG+VY ++ R+ K ++VA+ R+EQL PFP++ +++ +Y A+ I+WAQEE
Sbjct: 1067 ILCTGQVYAALLKHRQD-NKIDNVAITRIEQLHPFPWEQLRENLDQYTNAKTIVWAQEEP 1125
Query: 204 KNMGAWSFVQPRINSLLS----IDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFG 37
N GAWS+ QPR+ +LL+ D + YAGR PS+S ATG K +H++E+KE++ F
Sbjct: 1126 LNAGAWSYTQPRLETLLNHTKHHDRKHVMYAGRAPSASVATGKKSSHVKEEKELVDMAFS 1185
Query: 36 VPKSKLEG 13
V +SKL+G
Sbjct: 1186 VTQSKLKG 1193
>gi|16416078|emb|CAB91484.2| probable oxoglutarate dehydrogenase
precursor [Neurospora crassa]
Length = 1087
Score = 906 bits (2341), Expect = 0.0
Identities = 477/1028 (46%), Positives = 670/1028 (64%), Gaps = 26/1028 (2%)
Frame = -1
Query: 3018 GKSHISASTLVQHRNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRN 2839
G+ ++ S +H + + ++ FL+GS++ YI++MY W QDP SVH SW YF+N
Sbjct: 79 GRRPLAVSQQRRHESALHSPPDPNDNFLSGSAANYIDEMYLQWKQDPKSVHVSWQVYFKN 138
Query: 2838 VEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLL 2659
+E GA V P A + + A+V ++HLK+QLL
Sbjct: 139 MESGNMPISQAFQPPPSLVPGAANVVPGLA-----AGAGVGIGEGANV---TNHLKVQLL 190
Query: 2658 IRSYQTRGHNIADLDPLGIN----SADLDDTIPPELELSFYGLGERDLDREFLLPP---T 2500
+R+YQ RGH+ A++DPLGI S + P EL +YG E+DLD E+ L P
Sbjct: 191 VRAYQARGHHKANIDPLGIRNTPASKGFGNIRPKELTPEYYGFTEKDLDTEYSLGPGILP 250
Query: 2499 TFISE-KKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQK 2323
F + ++ +TLREI+ + IYC S GVE++H+ + E+ DW+R R E P+ + S D+K
Sbjct: 251 RFARDGREKMTLREIIDACEKIYCGSYGVEFIHIPDREKCDWLRERLEIPQPFKYSIDEK 310
Query: 2322 KVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPH 2143
+ + RLI S+ FE FLA K+P++KRFGLEGCE L+P MK +ID S GV VIGMPH
Sbjct: 311 RRILDRLIWSSSFESFLATKYPNDKRFGLEGCETLVPGMKALIDRSVDYGVKDIVIGMPH 370
Query: 2142 RGRLNVLANVCRQPLATILSQFSTLEPADE-GSGDVKYHLGVCIERLNRQSQKNVKIAVV 1966
RGRLNVL+NV R+P I S+F+ + ADE GSGDVKYHLG+ ER S K V++++V
Sbjct: 371 RGRLNVLSNVVRKPNEAIFSEFAGMAGADEEGSGDVKYHLGMNFERPT-PSGKRVQLSLV 429
Query: 1965 ANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRT-MAILLHGDAAFAGQGVVLETFNLDDLP 1789
ANPSHLEA DPVV+GKVRA Y DE ++ M +LLHGDAA AGQG+V E +LP
Sbjct: 430 ANPSHLEAEDPVVLGKVRAIQHYNNDESDHKSAMGVLLHGDAAIAGQGIVYECLGFHNLP 489
Query: 1788 SYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVA 1609
+++T G IH+VVNNQIGFTTDPR +RS+ YCTD+ + + P+FHVN DD EAV VC +A
Sbjct: 490 AFSTGGTIHLVVNNQIGFTTDPRFARSTAYCTDIAKAIDAPVFHVNADDVEAVNFVCQLA 549
Query: 1608 ADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVA 1429
+DWR FK+DVI+DLVCYR+HGHNE D+P FTQPLMY+RI + ++ Y +++L EG
Sbjct: 550 SDWRAEFKQDVIIDLVCYRKHGHNETDQPAFTQPLMYKRISEKSPQIDIYVDQLLKEGTF 609
Query: 1428 NEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPS------- 1270
++ ++E +LE+++ + K +++W S W++F + P +L S
Sbjct: 610 TKEDIEEHKQWVWGMLEESFSKS-KDYQPTSKEWTTSAWNNF---KSPKELASEVLPHMP 665
Query: 1269 TGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGR-QQMLKDNSLDWACGEALAFGSLLK 1093
T PEGF+ HR L+R L R + +++ +DWA EALAFG+L+K
Sbjct: 666 TAVDKPTLEHIGTVIGSTPEGFHAHRNLKRILTNRTKSVVEGKGIDWATAEALAFGTLVK 725
Query: 1092 EGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVL 913
EG HVR++GQDV+RGTFS RH V HDQ+ + Y PL +SE Q + + NSSLSEY +L
Sbjct: 726 EGHHVRITGQDVERGTFSQRHAVFHDQETED-TYIPLQHISEDQAPFVISNSSLSEYGIL 784
Query: 912 GFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGM 733
GFE GYS+ DPN +WEAQFGDF+NTAQ IIDQF++SG+SKW++++GLVM LPHGY+G
Sbjct: 785 GFEYGYSLQDPNGFNMWEAQFGDFANTAQVIIDQFLASGESKWMQRTGLVMSLPHGYDGQ 844
Query: 732 GPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRR 553
GPEHSSAR ERFL +CNED I E +Q D N +A T+PAN++H+LRR
Sbjct: 845 GPEHSSARMERFLSLCNEDPRIYPSPEKLE-----RQHQDCNMQIAYMTSPANLFHILRR 899
Query: 552 QVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPS---QNPPDVKRV 382
Q+ FRKP V+F K+LLRHP+ARS +E+F ++F+ ++P++ + + P +++RV
Sbjct: 900 QLKRQFRKPLVIFFSKALLRHPVARSDIEEFTDDAHFRWILPDSAHQTGEIKAPEEIERV 959
Query: 381 VFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAE-ILWAQEEH 205
+ CTG+VY ++ R+ K ++VA+ R+EQL PFP++ +++ +Y A+ I+WAQEE
Sbjct: 960 ILCTGQVYAALLKHRQD-NKIDNVAITRIEQLHPFPWEQLRENLDQYTNAKTIVWAQEEP 1018
Query: 204 KNMGAWSFVQPRINSLLS----IDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFG 37
N GAWS+ QPR+ +LL+ D + YAGR PS+S ATG K +H++E+KE++ F
Sbjct: 1019 LNAGAWSYTQPRLETLLNHTKHHDRKHVMYAGRAPSASVATGKKSSHVKEEKELVDMAFS 1078
Query: 36 VPKSKLEG 13
V +SKL+G
Sbjct: 1079 VTQSKLKG 1086
>gi|11252276|pir||T49683 probable oxoglutarate dehydrogenase precursor
[imported] - Neurospora crassa
Length = 1022
Score = 905 bits (2339), Expect = 0.0
Identities = 480/1041 (46%), Positives = 674/1041 (64%), Gaps = 33/1041 (3%)
Frame = -1
Query: 3036 IRNASSGKSHISASTLVQHRNQS-VAAAVKHEP------FLNGSSSIYIEQMYEAWLQDP 2878
+ ++++G+ H A + R+ + H P FL+GS++ YI++MY W QDP
Sbjct: 1 MHSSTAGRQHSLALAVCTDRSTDRPTPSALHSPPDPNDNFLSGSAANYIDEMYLQWKQDP 60
Query: 2877 SSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVTTSSAPATRLDTNAS 2698
SVH SW YF+N+E GA V P A + + A+
Sbjct: 61 KSVHVSWQVYFKNMESGNMPISQAFQPPPSLVPGAANVVPGLA-----AGAGVGIGEGAN 115
Query: 2697 VQSISDHLKIQLLIRSYQTRGHNIADLDPLGIN----SADLDDTIPPELELSFYGLGERD 2530
V ++HLK+QLL+R+YQ RGH+ A++DPLGI S + P EL +YG E+D
Sbjct: 116 V---TNHLKVQLLVRAYQARGHHKANIDPLGIRNTPASKGFGNIRPKELTPEYYGFTEKD 172
Query: 2529 LDREFLLPP---TTFISE-KKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRF 2362
LD E+ L P F + ++ +TLREI+ + IYC S GVE++H+ + E+ DW+R R
Sbjct: 173 LDTEYSLGPGILPRFARDGREKMTLREIIDACEKIYCGSYGVEFIHIPDREKCDWLRERL 232
Query: 2361 EAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSS 2182
E P+ + S D+K+ + RLI S+ FE FLA K+P++KRFGLEGCE L+P MK +ID S
Sbjct: 233 EIPQPFKYSIDEKRRILDRLIWSSSFESFLATKYPNDKRFGLEGCETLVPGMKALIDRSV 292
Query: 2181 TLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADE-GSGDVKYHLGVCIERL 2005
GV VIGMPHRGRLNVL+NV R+P I S+F+ + ADE GSGDVKYHLG+ ER
Sbjct: 293 DYGVKDIVIGMPHRGRLNVLSNVVRKPNEAIFSEFAGMAGADEEGSGDVKYHLGMNFERP 352
Query: 2004 NRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRT-MAILLHGDAAFAGQ 1828
S K V++++VANPSHLEA DPVV+GKVRA Y DE ++ M +LLHGDAA AGQ
Sbjct: 353 T-PSGKRVQLSLVANPSHLEAEDPVVLGKVRAIQHYNNDESDHKSAMGVLLHGDAAIAGQ 411
Query: 1827 GVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNV 1648
G+V E +LP+++T G IH+VVNNQIGFTTDPR +RS+ YCTD+ + + P+FHVN
Sbjct: 412 GIVYECLGFHNLPAFSTGGTIHLVVNNQIGFTTDPRFARSTAYCTDIAKAIDAPVFHVNA 471
Query: 1647 DDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTAL 1468
DD EAV VC +A+DWR FK+DVI+DLVCYR+HGHNE D+P FTQPLMY+RI + +
Sbjct: 472 DDVEAVNFVCQLASDWRAEFKQDVIIDLVCYRKHGHNETDQPAFTQPLMYKRISEKSPQI 531
Query: 1467 EKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKRD 1288
+ Y +++L EG ++ ++E +LE+++ + K +++W S W++F +
Sbjct: 532 DIYVDQLLKEGTFTKEDIEEHKQWVWGMLEESFSKS-KDYQPTSKEWTTSAWNNF---KS 587
Query: 1287 PLKLPS-------TGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGR-QQMLKDNSLDW 1132
P +L S T PEGF+ HR L+R L R + +++ +DW
Sbjct: 588 PKELASEVLPHMPTAVDKPTLEHIGTVIGSTPEGFHAHRNLKRILTNRTKSVVEGKGIDW 647
Query: 1131 ACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEY 952
A EALAFG+L+KEG HVR++GQDV+RGTFS RH V HDQ+ + Y PL +SE Q +
Sbjct: 648 ATAEALAFGTLVKEGHHVRITGQDVERGTFSQRHAVFHDQETED-TYIPLQHISEDQAPF 706
Query: 951 TVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQS 772
+ NSSLSEY +LGFE GYS+ DPN +WEAQFGDF+NTAQ IIDQF++SG+SKW++++
Sbjct: 707 VISNSSLSEYGILGFEYGYSLQDPNGFNMWEAQFGDFANTAQVIIDQFLASGESKWMQRT 766
Query: 771 GLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVAN 592
GLVM LPHGY+G GPEHSSAR ERFL +CNED I E +Q D N +A
Sbjct: 767 GLVMSLPHGYDGQGPEHSSARMERFLSLCNEDPRIYPSPEKLE-----RQHQDCNMQIAY 821
Query: 591 CTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAP 412
T+PAN++H+LRRQ+ FRKP V+F K+LLRHP+ARS +E+F ++F+ ++P++
Sbjct: 822 MTSPANLFHILRRQLKRQFRKPLVIFFSKALLRHPVARSDIEEFTDDAHFRWILPDSAHQ 881
Query: 411 S---QNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKY 241
+ + P +++RV+ CTG+VY ++ R+ K ++VA+ R+EQL PFP++ +++ +Y
Sbjct: 882 TGEIKAPEEIERVILCTGQVYAALLKHRQD-NKIDNVAITRIEQLHPFPWEQLRENLDQY 940
Query: 240 QGAE-ILWAQEEHKNMGAWSFVQPRINSLLS----IDGRATKYAGRLPSSSPATGNKFTH 76
A+ I+WAQEE N GAWS+ QPR+ +LL+ D + YAGR PS+S ATG K +H
Sbjct: 941 TNAKTIVWAQEEPLNAGAWSYTQPRLETLLNHTKHHDRKHVMYAGRAPSASVATGKKSSH 1000
Query: 75 MQEQKEMMSKVFGVPKSKLEG 13
++E+KE++ F V +SKL+G
Sbjct: 1001 VKEEKELVDMAFSVTQSKLKG 1021
>gi|15239128|ref|NP_201376.1| 2-oxoglutarate dehydrogenase E1
component, putative / oxoglutarate decarboxylase,
putative / alpha-ketoglutaric dehydrogenase, putative
[Arabidopsis thaliana]
gi|10177333|dbj|BAB10682.1| 2-oxoglutarate dehydrogenase, E1
component [Arabidopsis thaliana]
gi|18389254|gb|AAL67070.1| putative 2-oxoglutarate dehydrogenase E1
component [Arabidopsis thaliana]
gi|20465597|gb|AAM20281.1| putative 2-oxoglutarate dehydrogenase E1
component [Arabidopsis thaliana]
Length = 1025
Score = 894 bits (2309), Expect = 0.0
Identities = 480/1018 (47%), Positives = 647/1018 (63%), Gaps = 34/1018 (3%)
Frame = -1
Query: 2997 STLVQHRNQSVAAAVKHEP-------FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRN 2839
ST+++ + +S A + P FL+G+SS+Y+E++ AW DP+SV SWD +FRN
Sbjct: 43 STILKSKAESAAPVPRPVPLSKLTDSFLDGTSSVYLEELQRAWEADPNSVDESWDNFFRN 102
Query: 2838 VEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLL 2659
+ G SP S Q+I + +++ LL
Sbjct: 103 ------------------FVGQASTSP-----------------GISGQTIQESMRLLLL 127
Query: 2658 IRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLL---PPTTFIS 2488
+R+YQ GH A LDPLG+ + IP +L YG E DLDREF L + F+S
Sbjct: 128 VRAYQVNGHMKAKLDPLGLEKRE----IPEDLTPGLYGFTEADLDREFFLGVWRMSGFLS 183
Query: 2487 EKKSL-TLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLF 2311
E + + TLR IL RL+ YC + G EYMH+ + ++ +W+R + E P + + +++ V++
Sbjct: 184 ENRPVQTLRSILSRLEQAYCGTIGYEYMHIADRDKCNWLRDKIETPTPRQYNSERRMVIY 243
Query: 2310 KRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRL 2131
RL ST+FE FLA KW + KRFGLEG E LIP MK++ D S+ LGV++ VIGMPHRGRL
Sbjct: 244 DRLTWSTQFENFLATKWTTAKRFGLEGAESLIPGMKEMFDRSADLGVENIVIGMPHRGRL 303
Query: 2130 NVLANVCRQPLATILSQFS-TLEPADE-----GSGDVKYHLGVCIERLNRQSQKNVKIAV 1969
NVL NV R+PL I S+FS P DE G+GDVKYHLG +R R K++ +++
Sbjct: 304 NVLGNVVRKPLRQIFSEFSGGTRPVDEVGLYTGTGDVKYHLGTSYDRPTR-GGKHLHLSL 362
Query: 1968 VANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLP 1789
VANPSHLEAVDPVV+GK RA+ +Y DE + M IL+HGD +FAGQGVV ET +L LP
Sbjct: 363 VANPSHLEAVDPVVIGKTRAKQYYTKDENRTKNMGILIHGDGSFAGQGVVYETLHLSALP 422
Query: 1788 SYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVA 1609
+Y T G +HIVVNNQ+ FTTDPR RSS YCTDV + + PIFHVN DD EAV+H C +A
Sbjct: 423 NYCTGGTVHIVVNNQVAFTTDPREGRSSQYCTDVAKALSAPIFHVNADDIEAVVHACELA 482
Query: 1608 ADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVA 1429
A+WR+TF DV+VDLVCYRR GHNE+DEP FTQP MY+ I+ ++L+ YQEK+L G
Sbjct: 483 AEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIRSHPSSLQIYQEKLLQSGQV 542
Query: 1428 NEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXX 1249
++ + + K SIL + YE A K + RDWL S W F ++ +TG
Sbjct: 543 TQEDIDKIQKKVSSILNEEYE-ASKDYIPQKRDWLASHWTGFKSPEQISRIRNTGVKPEI 601
Query: 1248 XXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKD-NSLDWACGEALAFGSLLKEGIHVRL 1072
S +PE F HRG++R + R QM++ +DW GEALAF +L+ EG HVRL
Sbjct: 602 LKNVGKAISTFPENFKPHRGVKRVYEQRAQMIESGEGIDWGLGEALAFATLVVEGNHVRL 661
Query: 1071 SGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGE--YTVCNSSLSEYAVLGFELG 898
SGQDV+RGTFSHRH VLHDQ+ ++ Y PL+ L + Q +TV NSSLSE+ VLGFELG
Sbjct: 662 SGQDVERGTFSHRHSVLHDQETGEE-YCPLDHLIKNQDPEMFTVSNSSLSEFGVLGFELG 720
Query: 897 YSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHS 718
YSM +PNSLVIWEAQFGDF+N AQ + DQFISSG++KW+RQ+GLV+LLPHGY+G GPEHS
Sbjct: 721 YSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHS 780
Query: 717 SARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMP 538
S R ERFLQM +++ + E + T +Q+ + NW V N TTPAN +H+LRRQ+
Sbjct: 781 SGRLERFLQMSDDNPYVIPE---MDPTLR-KQIQECNWQVVNVTTPANYFHVLRRQIHRD 836
Query: 537 FRKPAVVFSPKSLLRHPMARSPVEDF----------QSGSNFQRVIPETGAPSQNPPDVK 388
FRKP +V +PK+LLRH S + +F + G+ F+R+I + S ++
Sbjct: 837 FRKPLIVMAPKNLLRHKQCVSNLSEFDDVKGHPGFDKQGTRFKRLIKDQSGHSDLEEGIR 896
Query: 387 RVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEE 208
R+V C+GKVYY++ RK + DVA+ RVEQL PFPYDL+Q+E ++Y AEI+W QEE
Sbjct: 897 RLVLCSGKVYYELDEERKK-SETKDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQEE 955
Query: 207 HKNMGAWSFVQPRINSLLSIDGRAT----KYAGRLPSSSPATGNKFTHMQEQKEMMSK 46
NMG + ++ R+ + + R KY GRLPS++ ATG H++EQ +++ K
Sbjct: 956 PMNMGGYQYIALRLCTAMKALQRGNFNDIKYVGRLPSAATATGFYQLHVKEQTDLVKK 1013
>gi|34394039|dbj|BAC84070.1| putative 2-oxoglutarate dehydrogenase, E1
subunit [Oryza sativa (japonica cultivar-group)]
Length = 1008
Score = 892 bits (2305), Expect = 0.0
Identities = 482/996 (48%), Positives = 648/996 (64%), Gaps = 29/996 (2%)
Frame = -1
Query: 2946 EPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALG 2767
+ FL+G+SS+Y+E++ AW DPSSV SWD +FRN
Sbjct: 50 DSFLDGTSSVYLEELQRAWEADPSSVDESWDNFFRNF----------------------- 86
Query: 2766 VSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADL 2587
Q SSA S Q+I + +++ LL+R+YQ GH A LDPL ++
Sbjct: 87 ----LGQAAPSSA-------GLSGQTIQESMQLLLLVRAYQVNGHMKAKLDPLRLD---- 131
Query: 2586 DDTIPPELELSFYGLGERDLDREFLLPP---TTFISEKKS-LTLREILQRLKDIYCTSTG 2419
D +P +L+LS YG E DLDREF L F+S+ + LTLREIL +L+ YC G
Sbjct: 132 DRAVPDDLDLSLYGFTEADLDREFFLGVWRMAGFLSDNRPVLTLREILSKLEQAYCGPIG 191
Query: 2418 VEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFG 2239
EYMH+ + ++ +W+R + E ++ E + D++ V+ RLI ST+FE FLA KW + KRFG
Sbjct: 192 YEYMHIPDRDKCNWLRDKIETAKLKEYNKDRRLVMLDRLIWSTQFENFLATKWATAKRFG 251
Query: 2238 LEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS----T 2071
LEG E LIP MK++ D ++ LGV++ VIGMPHRGRLNVL NV R+PL+ I S+F+
Sbjct: 252 LEGGETLIPGMKEMFDRAADLGVENIVIGMPHRGRLNVLGNVVRKPLSQIFSEFTGGTRP 311
Query: 2070 LEPAD---EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAF 1900
+E D G+GDVKYHLG +R R K + +++VANPSHLEAVDPVV+GK RA+ F
Sbjct: 312 VEGEDGLYTGTGDVKYHLGTSYDRPTRGG-KRIHLSLVANPSHLEAVDPVVIGKTRAKQF 370
Query: 1899 YAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPR 1720
Y+ D + M IL+HGD +FAGQGVV ET +L LPSYTT G IHIVVNNQ+ FTTDPR
Sbjct: 371 YSNDLDRTKNMGILIHGDGSFAGQGVVYETLHLSALPSYTTGGTIHIVVNNQVAFTTDPR 430
Query: 1719 SSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGH 1540
+ RSS YCTDV + + PIFHVN DD EAV+ VC +AA+WR+TF DV+VDL+CYRR GH
Sbjct: 431 AGRSSQYCTDVAKALNAPIFHVNGDDLEAVVRVCELAAEWRQTFHSDVVVDLICYRRFGH 490
Query: 1539 NELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENA 1360
NE+DEP FTQP MYQ IK ++L+ Y++K+L G +++ V++ K IL + E A
Sbjct: 491 NEIDEPSFTQPKMYQVIKNHPSSLKLYEQKLLGTGEVSKEDVQKIHEKVNRILNE--EFA 548
Query: 1359 QKVTYVRN-RDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLE 1183
+ YV N RDWL + W F ++ +TG + PE F HR ++
Sbjct: 549 KSKDYVPNKRDWLSAYWTGFKSPEQISRVRNTGVNPGVLKRVGQAITTLPEDFKPHRAVK 608
Query: 1182 RTLKGRQQMLKD-NSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKV 1006
+ + R M++ +DWA EALAF +L+ EG HVRLSGQDV+RGTFSHRH VLHDQ+
Sbjct: 609 KIFEQRAAMIESGEGIDWAVAEALAFATLIVEGNHVRLSGQDVERGTFSHRHAVLHDQEN 668
Query: 1005 DQKIYNPLNDLSEGQGE--YTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNT 832
+K + PL+ + Q E +TV NSSLSE+AVLGFE+GYSM +PNSLV+WEAQFGDFSN
Sbjct: 669 GRK-HCPLDHVVMNQNEELFTVSNSSLSEFAVLGFEMGYSMENPNSLVLWEAQFGDFSNG 727
Query: 831 AQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKI 652
AQ + DQF+SSG++KW+RQ+GLV+LLPHGY+G GPEHSSAR ERFLQM +++ + E
Sbjct: 728 AQVMFDQFLSSGEAKWLRQTGLVVLLPHGYDGQGPEHSSARLERFLQMSDDNPFVIPE-- 785
Query: 651 AFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSP 472
E T +Q+ + NW V N TTPAN +H+LRRQ+ FRKP +V +PK+LLRH +S
Sbjct: 786 -MEPTLR-KQIQECNWQVVNVTTPANYFHVLRRQIHREFRKPLIVMAPKNLLRHKDCKSN 843
Query: 471 VEDF----------QSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGK 322
+ +F + G+ F+R+I + Q +KR+V C+GKVYY++ RK +
Sbjct: 844 LSEFDDVEGHPGFDKQGTRFKRLIKDRNDHKQVEEGIKRLVLCSGKVYYELDEERKKT-E 902
Query: 321 ENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDG 142
+DVA+ RVEQL PFPYDL+Q+E ++Y AEI+W QEE NMGA+S++ PR+ + + G
Sbjct: 903 RSDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQEEPMNMGAYSYISPRLYASMKTLG 962
Query: 141 RAT----KYAGRLPSSSPATGNKFTHMQEQKEMMSK 46
R + KY GR PS++ ATG H QEQ E++ K
Sbjct: 963 RGSFDDIKYVGRAPSAATATGFLSVHAQEQTELVKK 998
>gi|11252274|pir||T50644 oxoglutarate dehydrogenase (lipoamide) (EC
1.2.4.2) E1 chain [imported] - Arabidopsis thaliana
gi|4210330|emb|CAA11552.1| 2-oxoglutarate dehydrogenase, E1 subunit
[Arabidopsis thaliana]
Length = 1027
Score = 889 bits (2296), Expect = 0.0
Identities = 480/1020 (47%), Positives = 647/1020 (63%), Gaps = 36/1020 (3%)
Frame = -1
Query: 2997 STLVQHRNQSVAAAVKHEP-------FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRN 2839
ST+++ + +S A + P FL+G+SS+Y+E++ AW DP+SV SWD +FRN
Sbjct: 43 STILKSKAESAAPVPRPVPLSKLTDSFLDGTSSVYLEELQRAWEADPNSVDESWDNFFRN 102
Query: 2838 VEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLL 2659
+ G SP S Q+I + +++ LL
Sbjct: 103 ------------------FVGQASTSP-----------------GISGQTIQESMRLLLL 127
Query: 2658 IRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLL---PPTTFIS 2488
+R+YQ GH A LDPLG+ + IP +L YG E DLDREF L + F+S
Sbjct: 128 VRAYQVNGHMKAKLDPLGLEKRE----IPEDLTPGLYGFTEADLDREFFLGVWRMSGFLS 183
Query: 2487 EKKSL-TLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLF 2311
E + + TLR IL RL+ YC + G EYMH+ + ++ +W+R + E P + + +++ V++
Sbjct: 184 ENRPVQTLRSILSRLEQAYCGTIGYEYMHIADRDKCNWLRDKIETPTPRQYNSERRMVIY 243
Query: 2310 KRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRL 2131
RL ST+FE FLA KW + KRFGLEG E LIP MK++ D S+ LGV++ VIGMPHRGRL
Sbjct: 244 DRLTWSTQFENFLATKWTTAKRFGLEGAESLIPGMKEMFDRSADLGVENIVIGMPHRGRL 303
Query: 2130 NVLANVCRQPLATILSQFS-TLEPADE-----GSGDVKYHLGVCIERLNRQSQKNVKIAV 1969
NVL NV R+PL I S+FS P DE G+GDVKYHLG +R R K++ +++
Sbjct: 304 NVLGNVVRKPLRQIFSEFSGGTRPVDEVGLYTGTGDVKYHLGTSYDRPTR-GGKHLHLSL 362
Query: 1968 VANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLP 1789
VANPSHLEAVDPVV+GK RA+ +Y DE + M IL+HGD +FAGQGVV ET +L LP
Sbjct: 363 VANPSHLEAVDPVVIGKTRAKQYYTKDENRTKNMGILIHGDGSFAGQGVVYETLHLSALP 422
Query: 1788 SYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVA 1609
+Y T G +HIVVNNQ+ FTTDPR RSS YCTDV + + PIFHVN DD EAV+H C +A
Sbjct: 423 NYCTGGTVHIVVNNQVAFTTDPREGRSSQYCTDVAKALSAPIFHVNADDIEAVVHACELA 482
Query: 1608 ADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVA 1429
A+WR+TF DV+VDLVCYRR GHNE+DEP FTQP MY+ I+ ++L+ YQEK+L G
Sbjct: 483 AEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIRSHPSSLQIYQEKLLQSGQV 542
Query: 1428 NEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXX 1249
++ + + K SIL + YE A K + RDWL S W F ++ +TG
Sbjct: 543 TQEDIDKIQKKVSSILNEEYE-ASKDYIPQKRDWLASHWTGFKSPEQISRIRNTGVKPEI 601
Query: 1248 XXXXIGKFSQYPEGFNLHRGLE--RTLKGRQQMLKD-NSLDWACGEALAFGSLLKEGIHV 1078
S +PE F HRG++ R + R QM++ +DW GEALAF +L+ EG HV
Sbjct: 602 LKNVGKAISTFPENFKPHRGVKRVRVYEQRAQMIESGEGIDWGLGEALAFATLVVEGNHV 661
Query: 1077 RLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGE--YTVCNSSLSEYAVLGFE 904
RLSGQDV+RGTFSHRH VLHDQ+ ++ Y PL+ L + Q +TV NSSLSE+ VLGFE
Sbjct: 662 RLSGQDVERGTFSHRHSVLHDQETGEE-YCPLDHLIKNQDPEMFTVSNSSLSEFGVLGFE 720
Query: 903 LGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPE 724
LGYSM +PNSLVIWEAQFGDF+N AQ + DQFISSG++KW+RQ+GLV+LLPHGY+G GPE
Sbjct: 721 LGYSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPE 780
Query: 723 HSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVT 544
HSS R ERFLQM +++ + E + T +Q+ + NW V N TTPAN +H+LRRQ+
Sbjct: 781 HSSGRLERFLQMSDDNPYVIPE---MDPTLR-KQIQECNWQVVNVTTPANYFHVLRRQIH 836
Query: 543 MPFRKPAVVFSPKSLLRHPMARSPVEDF----------QSGSNFQRVIPETGAPSQNPPD 394
FRKP +V +PK+LLRH S + +F + G+ F+R+I + S
Sbjct: 837 RDFRKPLIVMAPKNLLRHKQCVSNLSEFDDVKGHPGFDKQGTRFKRLIKDQSGHSDLEEG 896
Query: 393 VKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQ 214
++R+V C+GKVYY++ RK + DVA+ RVEQL PFPYDL+Q+E ++Y AEI+W Q
Sbjct: 897 IRRLVLCSGKVYYELDEERKK-SETKDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQ 955
Query: 213 EEHKNMGAWSFVQPRINSLLSIDGRAT----KYAGRLPSSSPATGNKFTHMQEQKEMMSK 46
EE NMG + ++ R+ + + R KY GRLPS++ ATG H++EQ +++ K
Sbjct: 956 EEPMNMGGYQYIALRLCTAMKALQRGNFNDIKYVGRLPSAATATGFYQLHVKEQTDLVKK 1015
>gi|30694242|ref|NP_191101.2| 2-oxoglutarate dehydrogenase E1
component, putative / oxoglutarate decarboxylase,
putative / alpha-ketoglutaric dehydrogenase, putative
[Arabidopsis thaliana]
Length = 1017
Score = 882 bits (2278), Expect = 0.0
Identities = 473/998 (47%), Positives = 637/998 (63%), Gaps = 28/998 (2%)
Frame = -1
Query: 2946 EPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALG 2767
+ FL+G+SS+Y+E++ AW DP+SV SWD +FRN + G
Sbjct: 64 DSFLDGTSSVYLEELQRAWEADPNSVDESWDNFFRN------------------FVGQAA 105
Query: 2766 VSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADL 2587
SP S Q+I + +++ LL+R+YQ GH A LDPLG+ +
Sbjct: 106 TSP-----------------GISGQTIQESMRLLLLVRAYQVNGHMKAKLDPLGLEQRE- 147
Query: 2586 DDTIPPELELSFYGLGERDLDREFLL---PPTTFISEKKSL-TLREILQRLKDIYCTSTG 2419
IP +L+L+ YG E DLDREF L + F+SE + + TLR IL RL+ YC + G
Sbjct: 148 ---IPEDLDLALYGFTEADLDREFFLGVWQMSGFMSENRPVQTLRSILTRLEQAYCGNIG 204
Query: 2418 VEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFG 2239
EYMH+ + ++ +W+R + E P + ++++V+ RL ST+FE FLA KW + KRFG
Sbjct: 205 FEYMHIADRDKCNWLREKIETPTPWRYNRERREVILDRLAWSTQFENFLATKWTTAKRFG 264
Query: 2238 LEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEP 2062
LEG E LIP MK++ D ++ LGV+S VIGM HRGRLNVL NV R+PL I S+FS + P
Sbjct: 265 LEGGESLIPGMKEMFDRAADLGVESIVIGMSHRGRLNVLGNVVRKPLRQIFSEFSGGIRP 324
Query: 2061 ADE----GSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYA 1894
DE G+GDVKYHLG +R R +K + +++VANPSHLEA D VV+GK RA+ +Y+
Sbjct: 325 VDEVGYTGTGDVKYHLGTSYDRPTRGGKK-IHLSLVANPSHLEAADSVVVGKTRAKQYYS 383
Query: 1893 GDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSS 1714
D + + IL+HGD +FAGQGVV ET +L LP+YTT G IHIVVNNQ+ FTTDPR+
Sbjct: 384 NDLDRTKNLGILIHGDGSFAGQGVVYETLHLSALPNYTTGGTIHIVVNNQVAFTTDPRAG 443
Query: 1713 RSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNE 1534
RSS YCTDV + + PIFHVN DD EAV+H C +AA+WR+TF DV+VDLVCYRR GHNE
Sbjct: 444 RSSQYCTDVAKALSAPIFHVNGDDVEAVVHACELAAEWRQTFHSDVVVDLVCYRRFGHNE 503
Query: 1533 LDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQK 1354
+DEP FTQP MY+ IK + L+ Y +K+L G ++Q + K +IL + + A K
Sbjct: 504 IDEPSFTQPKMYKVIKNHPSTLQIYHKKLLECGEVSQQDIDRIQEKVNTILNEEFV-ASK 562
Query: 1353 VTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTL 1174
+ RDWL + W F ++ +TG S PE F HR +++
Sbjct: 563 DYLPKKRDWLSTNWAGFKSPEQISRVRNTGVKPEILKTVGKAISSLPENFKPHRAVKKVY 622
Query: 1173 KGRQQMLKD-NSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQK 997
+ R QM++ +DWA EALAF +L+ EG HVRLSGQDV+RGTFSHRH VLHDQ+ ++
Sbjct: 623 EQRAQMIESGEGVDWALAEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEE 682
Query: 996 IYNPLNDLSEGQGE--YTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQC 823
Y PL+ L Q +TV NSSLSE+ VLGFELGYSM PNSLV+WEAQFGDF+N AQ
Sbjct: 683 -YCPLDHLIMNQDPEMFTVSNSSLSEFGVLGFELGYSMESPNSLVLWEAQFGDFANGAQV 741
Query: 822 IIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI--DLEKIA 649
I DQFISSG++KW+RQ+GLVMLLPHGY+G GPEHSSAR ER+LQM +++ + D+E
Sbjct: 742 IFDQFISSGEAKWLRQTGLVMLLPHGYDGQGPEHSSARLERYLQMSDDNPYVIPDMEPTM 801
Query: 648 FEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPV 469
+Q+ + NW + N TTPAN +H+LRRQ+ FRKP +V +PK+LLRH +S +
Sbjct: 802 ------RKQIQECNWQIVNATTPANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKDCKSNL 855
Query: 468 EDF----------QSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKE 319
+F + G+ F+R+I + S ++R+V C+GKVYY++ RK VG
Sbjct: 856 SEFDDVQGHPGFDKQGTRFKRLIKDQNDHSDLEEGIRRLVLCSGKVYYELDDERKKVG-A 914
Query: 318 NDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRI----NSLLS 151
DVA+ RVEQL PFPYDL+Q+E ++Y AEI+W QEE NMGA+S++ PR+ S+
Sbjct: 915 TDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQEEAMNMGAFSYISPRLWTAMRSVNR 974
Query: 150 IDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFG 37
D KY GR PS++ ATG H++EQ ++ K G
Sbjct: 975 GDMEDIKYVGRGPSAATATGFYTFHVKEQAGLVQKAIG 1012
>gi|28416717|gb|AAO42889.1| At3g55410 [Arabidopsis thaliana]
Length = 1017
Score = 881 bits (2276), Expect = 0.0
Identities = 473/998 (47%), Positives = 638/998 (63%), Gaps = 28/998 (2%)
Frame = -1
Query: 2946 EPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALG 2767
+ FL+G+SS+Y+E++ AW DP+SV SWD +FRN + G
Sbjct: 64 DSFLDGTSSVYLEELQRAWEADPNSVDESWDNFFRN------------------FVGQAA 105
Query: 2766 VSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADL 2587
SP S Q+I + +++ LL+R+YQ GH A LDPLG+ +
Sbjct: 106 TSP-----------------GISGQTIQESMRLLLLVRAYQVNGHMKAKLDPLGLEQRE- 147
Query: 2586 DDTIPPELELSFYGLGERDLDREFLL---PPTTFISEKKSL-TLREILQRLKDIYCTSTG 2419
IP +L+L+ YG E DLDREF L + F+SE + + TLR IL RL+ YC + G
Sbjct: 148 ---IPEDLDLALYGFTEADLDREFFLGVWQMSGFMSENRPVQTLRSILTRLEQAYCGNIG 204
Query: 2418 VEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFG 2239
EYMH+ + ++ +W+R + E P + ++++V+ RL ST+FE FLA KW + KRFG
Sbjct: 205 FEYMHIADRDKCNWLREKIETPTPWRYNRERREVILDRLAWSTQFENFLATKWTTAKRFG 264
Query: 2238 LEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEP 2062
LEG E LIP MK++ D ++ LGV+S VIGM HRGRLNVL+NV R+PL I S+FS + P
Sbjct: 265 LEGGESLIPGMKEMFDRAADLGVESIVIGMSHRGRLNVLSNVVRKPLRQIFSEFSGGIRP 324
Query: 2061 ADE----GSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYA 1894
DE G+GDVKYHLG +R R +K + +++VANPSHLEA D VV+GK RA+ +Y+
Sbjct: 325 VDEVGYTGTGDVKYHLGTSYDRPTRGGKK-IHLSLVANPSHLEAADSVVVGKTRAKQYYS 383
Query: 1893 GDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSS 1714
D + + IL+HGD +FAGQGVV ET +L LP+YTT G IHIVVNNQ+ FTTDPR+
Sbjct: 384 NDLDRTKNLGILIHGDGSFAGQGVVYETLHLSALPNYTTGGTIHIVVNNQVVFTTDPRAG 443
Query: 1713 RSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNE 1534
RSS YCTDV + + PIFHVN DD EAV+H C +AA+WR+TF DV+VDLVCYRR GHNE
Sbjct: 444 RSSQYCTDVAKALSAPIFHVNGDDVEAVVHACELAAEWRQTFHSDVVVDLVCYRRFGHNE 503
Query: 1533 LDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQK 1354
+DEP FTQP MY+ IK + L+ Y +K+L G ++Q + K +IL + + A K
Sbjct: 504 IDEPSFTQPKMYKVIKNHPSTLQIYHKKLLECGEVSQQDIDRIQEKVNTILNEEFV-ASK 562
Query: 1353 VTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTL 1174
+ RDWL + W F ++ +TG S PE F HR +++
Sbjct: 563 DYLPKKRDWLSTNWAGFKSPEQISRVRNTGVKPEILKTVGKAISSLPENFKPHRAVKKVY 622
Query: 1173 KGRQQMLKD-NSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQK 997
+ R QM++ +DWA EALAF +L+ EG HVRLSGQDV+RGTFSHRH VLHDQ+ ++
Sbjct: 623 EQRAQMIESGEGVDWALAEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEE 682
Query: 996 IYNPLNDLSEGQGE--YTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQC 823
Y PL+ L Q +TV NSSLSE+ VLGFELGYSM PNSLV+WEAQFGDF+N AQ
Sbjct: 683 -YCPLDHLIMNQDPEMFTVSNSSLSEFGVLGFELGYSMESPNSLVLWEAQFGDFANGAQV 741
Query: 822 IIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI--DLEKIA 649
I DQFISSG++KW+RQ+GLVMLLPHGY+G GPEHSSAR ER+LQM +++ + D+E
Sbjct: 742 IFDQFISSGEAKWLRQTGLVMLLPHGYDGQGPEHSSARLERYLQMSDDNPYVIPDMEPTM 801
Query: 648 FEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPV 469
+Q+ + NW + N TTPAN +H+LRRQ+ FRKP +V +PK+LLRH +S +
Sbjct: 802 ------RKQIQECNWQIVNATTPANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKDCKSNL 855
Query: 468 EDF----------QSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKE 319
+F + G+ F+R+I + S ++R+V C+GKVYY++ RK VG
Sbjct: 856 SEFDDVQGHPGFDKQGTRFKRLIKDQNDHSDLEEGIRRLVLCSGKVYYELDDERKKVG-A 914
Query: 318 NDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRI----NSLLS 151
DVA+ RVEQL PFPYDL+Q+E ++Y AEI+W QEE NMGA+S++ PR+ S+
Sbjct: 915 TDVAICRVEQLCPFPYDLIQRELKRYPNAEIVWCQEEAMNMGAFSYISPRLWTAMRSVNR 974
Query: 150 IDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFG 37
D KY GR PS++ ATG H++EQ ++ K G
Sbjct: 975 GDMEDIKYVGRGPSAATATGFYTFHVKEQAGLVQKAIG 1012
>gi|49076112|ref|XP_402067.1| hypothetical protein UM04452.1 [Ustilago
maydis 521]
gi|46100487|gb|EAK85720.1| hypothetical protein UM04452.1 [Ustilago
maydis 521]
Length = 1221
Score = 881 bits (2276), Expect = 0.0
Identities = 486/1046 (46%), Positives = 648/1046 (61%), Gaps = 28/1046 (2%)
Frame = -1
Query: 3081 ASLICRLASPSRINAIRNASSGKSHISASTLVQHRNQSVAAAVKHEP-----FLNGSSSI 2917
AS+ RL + +NA S +S+ S+S Q + S A A + P F+N +++
Sbjct: 203 ASVSARLPNRCTLNA-----SLRSYQSSS---QSQQASPAPAKPNAPSGSDTFINTTNAY 254
Query: 2916 YIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVTT 2737
Y E+M++ W QDP SVH SWD YF + A P +
Sbjct: 255 YAEEMHKLWKQDPKSVHASWDVYFSGLAKGLASEH------------AFRAPPTLMPLPM 302
Query: 2736 SSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELEL 2557
+ P + S ++ DHLK+QLL+R+YQ RGH IA LDPLGI DLD +P EL++
Sbjct: 303 EAPPVDVSGFSGSTDAVDDHLKLQLLVRAYQVRGHRIARLDPLGILDPDLDPNVPEELKI 362
Query: 2556 SFYGLGERDLDREFLLPP---TTFI-SEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLE 2389
YG + DLDR+ L P F+ S LT+REI+ K +YC S GV+Y+H+ + E
Sbjct: 363 EHYGWSQADLDRKMRLGPGLLPNFVDSGIHELTIREIIDACKRMYCGSIGVQYVHIPDRE 422
Query: 2388 QQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPA 2209
+ DW+R+R E P + S ++K+ + RLI S FE F+A K+P+EKRFGLEG E LIP
Sbjct: 423 KCDWLRKRIETPEPFKYSVEEKRTILDRLIWSDSFERFIASKYPNEKRFGLEGGESLIPG 482
Query: 2208 MKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVKYH 2029
+K +ID S GVDS IGMPHRGRLNVLANV R+P+ IL QF+ E EG GDVKYH
Sbjct: 483 LKTLIDRSVEHGVDSVTIGMPHRGRLNVLANVIRRPIEGILHQFAAKEDDGEGGGDVKYH 542
Query: 2028 LGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHG 1849
LG R S K V +++VANPSHLEA DPVV+GK RA +A D++ +MA+L+HG
Sbjct: 543 LGANYVRPT-PSGKKVALSLVANPSHLEAEDPVVLGKTRALQDFAKDKEHATSMALLMHG 601
Query: 1848 DAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGC 1669
DAAFAGQGVV ET + +LP+Y T G +HIVVNNQIGFTTDPR +RS+PY +D+ + +
Sbjct: 602 DAAFAGQGVVYETMGMYNLPNYATGGTVHIVVNNQIGFTTDPRFARSTPYPSDIAKSIDA 661
Query: 1668 PIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRI 1489
PIFHVN DD EAV V +AADWR TFKKDV++DLVCYRRHGHNE D+P FTQP MY I
Sbjct: 662 PIFHVNGDDVEAVTFVSQLAADWRATFKKDVVIDLVCYRRHGHNETDQPSFTQPRMYAAI 721
Query: 1488 KQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWD 1309
+ L KY ++++EG + ++E +LE+A++ ++ R+WL S W+
Sbjct: 722 AKQDPTLSKYAARLVDEGSFTKSDIEEHQKWVWGMLEEAFDKSKNYR-PEEREWLSSAWE 780
Query: 1308 DFFKKR----DPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKD-N 1144
F + L TG S YP+ F +HR L R LK R + +++
Sbjct: 781 GFPSPKQLAEQILDHKDTGVKEQTLKHIGKTVSTYPDDFTVHRNLGRILKTRLKTVEEGK 840
Query: 1143 SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEG 964
++D + GEALAFGSL EG +VRLSGQDV+RGTFS RH VLHDQ+ ++ Y PL + EG
Sbjct: 841 NIDMSTGEALAFGSLALEGNYVRLSGQDVERGTFSQRHSVLHDQE-NEGTYTPLQHVGEG 899
Query: 963 QGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKW 784
Q + VCNSSLSE+ +GFELG+S+V P +L IWEAQFGDF+N AQCIIDQFI+SG+ KW
Sbjct: 900 QAPFVVCNSSLSEFGCMGFELGFSLVSPQNLTIWEAQFGDFANNAQCIIDQFIASGERKW 959
Query: 783 IRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLH-DTN 607
++++GLV+ LPHGY+G GPEHSSAR ERFLQ+C++ F ++ + H D+N
Sbjct: 960 LQRTGLVLNLPHGYDGQGPEHSSARIERFLQLCDD------HPFKFPTPEKSNRQHQDSN 1013
Query: 606 WIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIP 427
V CTTPAN +H+LRRQV FRKP V F KSLLRHP ARS ++DF G+ FQR IP
Sbjct: 1014 MAVVYCTTPANYFHVLRRQVHRDFRKPLVNFFSKSLLRHPEARSNLQDFLPGTGFQRFIP 1073
Query: 426 ETGAPSQN-----PPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLV 262
E A P +KR + G+ Y++++ R+ DVA+ R+EQLSP Y+ V
Sbjct: 1074 EPHASEGKDELVAPDQIKRHILTFGQTYFELLKHRRE-NNIKDVAISRIEQLSPLHYEAV 1132
Query: 261 QQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKY--------AGRLPSS 106
Q KY A++++ QEE N GAWS++QPR+ + R T++ A R PSS
Sbjct: 1133 VQALDKYPNADLVFCQEEPLNNGAWSYLQPRLRTAC----RHTQHHKNDIVILASRPPSS 1188
Query: 105 SPATGNKFTHMQEQKEMMSKVFGVPK 28
S ATG+K H E + + F + +
Sbjct: 1189 SVATGSKVAHKAEVEAYLKDAFDLDR 1214
>gi|25012868|gb|AAN71522.1| RH09189p [Drosophila melanogaster]
Length = 758
Score = 874 bits (2259), Expect = 0.0
Identities = 420/690 (60%), Positives = 519/690 (74%), Gaps = 3/690 (0%)
Frame = -1
Query: 2109 RQPLATILSQFSTLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPV 1930
R+PL I +QF+ LE AD+GSGDVKYHLG IERLNR + KN+++AVVANPSHLEAVDPV
Sbjct: 68 RKPLNQIFTQFAGLEAADDGSGDVKYHLGTYIERLNRVTNKNIRLAVVANPSHLEAVDPV 127
Query: 1929 VMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVN 1750
V GK RAE FY GD++ + M+IL+HGDAAF GQGVV ET +L DLP YTTHG IH+V N
Sbjct: 128 VQGKTRAEQFYRGDQEGKKVMSILIHGDAAFCGQGVVYETMHLSDLPDYTTHGTIHVVAN 187
Query: 1749 NQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIV 1570
NQIGFTTDPR SRSSPYCTDV RVV PIFHVN DDPEAVMHVC VAA+WR TF KD ++
Sbjct: 188 NQIGFTTDPRFSRSSPYCTDVARVVNAPIFHVNADDPEAVMHVCKVAAEWRATFHKDCVI 247
Query: 1569 DLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYG 1390
DLV YRR+GHNE+DEPMFTQPLMYQ+I++ K L+ Y +K++ EG + VK KY
Sbjct: 248 DLVGYRRNGHNEIDEPMFTQPLMYQKIRKHKNCLDLYADKLIAEGTVTAEEVKSVAAKYE 307
Query: 1389 SILEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPE 1210
+I E+A+ A+ T+V+ +DWLDSPW FF+ +DPLK+ TG +FS P
Sbjct: 308 NICEEAFALAKTETHVKYKDWLDSPWSGFFEGKDPLKVAPTGVKEETLIHIGNRFSSPPP 367
Query: 1209 G---FNLHRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFS 1039
F +H+GL R L R+ M+ + DWA GEA+AFGSLLKEGIHVRLSGQDV+RGTFS
Sbjct: 368 NAAEFVIHKGLLRVLAARKAMVDEKVADWALGEAMAFGSLLKEGIHVRLSGQDVERGTFS 427
Query: 1038 HRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWE 859
HRHHVLH Q VD+ YN L + Q Y+V NSSLSEYAVLGFE GYSM +PN+LV+WE
Sbjct: 428 HRHHVLHHQLVDKATYNSLQHMYPDQAPYSVSNSSLSEYAVLGFEHGYSMTNPNALVLWE 487
Query: 858 AQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNE 679
AQFGDFSNTAQ IIDQFISSGQSKW+RQSGLVMLLPHG EG+GPEHSS R ERFLQM ++
Sbjct: 488 AQFGDFSNTAQSIIDQFISSGQSKWVRQSGLVMLLPHGMEGIGPEHSSCRVERFLQMSSD 547
Query: 678 DDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSL 499
D + + F +QLHD NWIVANC+TPAN YH+LRRQ+ +PFRKP ++ +PKSL
Sbjct: 548 DPDYFPPE---SDEFGVRQLHDINWIVANCSTPANYYHILRRQIALPFRKPLILCTPKSL 604
Query: 498 LRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKE 319
LRHP A+SP + GS FQR+IP+ G QNP +VK+VVFC+G+VYYD+ R+ E
Sbjct: 605 LRHPEAKSPFGEMSEGSEFQRIIPDNGPAGQNPSNVKKVVFCSGRVYYDLTKTRREKQLE 664
Query: 318 NDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGR 139
++A+VRVEQ+SPFP+DLV+++ Y+ AE++WAQEEHKN G+W++VQPR + L+ R
Sbjct: 665 GEIAIVRVEQISPFPFDLVKEQANLYKNAELVWAQEEHKNQGSWTYVQPRFLTALN-HSR 723
Query: 138 ATKYAGRLPSSSPATGNKFTHMQEQKEMMS 49
Y GR +S ATG+K H++E +++
Sbjct: 724 DVSYVGRACGASTATGSKAQHIRELNALLN 753
>gi|28574585|ref|NP_730226.2| CG11661-PE [Drosophila melanogaster]
gi|28380496|gb|AAN11723.2| CG11661-PE [Drosophila melanogaster]
Length = 778
Score = 874 bits (2259), Expect = 0.0
Identities = 420/688 (61%), Positives = 517/688 (75%), Gaps = 3/688 (0%)
Frame = -1
Query: 2103 PLATILSQFSTLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVM 1924
PL I +QF+ LE AD+GSGDVKYHLG IERLNR + KN+++AVVANPSHLEAVDPVV
Sbjct: 90 PLNQIFTQFAGLEAADDGSGDVKYHLGTYIERLNRVTNKNIRLAVVANPSHLEAVDPVVQ 149
Query: 1923 GKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQ 1744
GK RAE FY GD++ + M+IL+HGDAAF GQGVV ET +L DLP YTTHG IH+V NNQ
Sbjct: 150 GKTRAEQFYRGDQEGKKVMSILIHGDAAFCGQGVVYETMHLSDLPDYTTHGTIHVVANNQ 209
Query: 1743 IGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDL 1564
IGFTTDPR SRSSPYCTDV RVV PIFHVN DDPEAVMHVC VAA+WR TF KD ++DL
Sbjct: 210 IGFTTDPRFSRSSPYCTDVARVVNAPIFHVNADDPEAVMHVCKVAAEWRATFHKDCVIDL 269
Query: 1563 VCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSI 1384
V YRR+GHNE+DEPMFTQPLMYQ+I++ K L+ Y +K++ EG + VK KY +I
Sbjct: 270 VGYRRNGHNEIDEPMFTQPLMYQKIRKHKNCLDLYADKLIAEGTVTAEEVKSVAAKYENI 329
Query: 1383 LEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEG- 1207
E+A+ A+ T+V+ +DWLDSPW FF+ +DPLK+ TG +FS P
Sbjct: 330 CEEAFALAKTETHVKYKDWLDSPWSGFFEGKDPLKVAPTGVKEETLIHIGNRFSSPPPNA 389
Query: 1206 --FNLHRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHR 1033
F +H+GL R L R+ M+ + DWA GEA+AFGSLLKEGIHVRLSGQDV+RGTFSHR
Sbjct: 390 AEFVIHKGLLRVLAARKAMVDEKVADWALGEAMAFGSLLKEGIHVRLSGQDVERGTFSHR 449
Query: 1032 HHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQ 853
HHVLH Q VD+ YN L + Q Y+V NSSLSEYAVLGFE GYSM +PN+LV+WEAQ
Sbjct: 450 HHVLHHQLVDKATYNSLQHMYPDQAPYSVSNSSLSEYAVLGFEHGYSMTNPNALVLWEAQ 509
Query: 852 FGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDD 673
FGDFSNTAQ IIDQFISSGQSKW+RQSGLVMLLPHG EGMGPEHSS R ERFLQM ++D
Sbjct: 510 FGDFSNTAQSIIDQFISSGQSKWVRQSGLVMLLPHGMEGMGPEHSSCRVERFLQMSSDDP 569
Query: 672 EIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLR 493
+ + F +QLHD NWIVANC+TPAN YH+LRRQ+ +PFRKP ++ +PKSLLR
Sbjct: 570 DYFPPE---SDEFGVRQLHDINWIVANCSTPANYYHILRRQIALPFRKPLILCTPKSLLR 626
Query: 492 HPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKEND 313
HP A+SP + GS FQR+IP+ G QNP +VK+VVFC+G+VYYD+ R+ E +
Sbjct: 627 HPEAKSPFSEMSEGSEFQRIIPDNGPAGQNPSNVKKVVFCSGRVYYDLTKTRREKQLEGE 686
Query: 312 VALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRAT 133
+A+VRVEQ+SPFP+DLV+++ Y+ AE++WAQEEHKN G+W++VQPR + L+ R
Sbjct: 687 IAIVRVEQISPFPFDLVKEQANLYKNAELVWAQEEHKNQGSWTYVQPRFLTALN-HSRDV 745
Query: 132 KYAGRLPSSSPATGNKFTHMQEQKEMMS 49
Y GR +S ATG+K H++E +++
Sbjct: 746 SYVGRACGASTATGSKAQHIRELNALLN 773
Score = 69.3 bits (168), Expect = 5e-10
Identities = 31/64 (48%), Positives = 46/64 (71%)
Frame = -1
Query: 3030 NASSGKSHISASTLVQHRNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDA 2851
++S + ++A+ V+ N + A EPF NGS++ Y+E+MY AWL+DP+SVHTSWDA
Sbjct: 28 SSSQQMAKVTAAAAVRTYNSAAA-----EPFANGSTASYVEEMYNAWLRDPTSVHTSWDA 82
Query: 2850 YFRN 2839
YFR+
Sbjct: 83 YFRS 86
>gi|46116934|ref|XP_384485.1| conserved hypothetical protein
[Gibberella zeae PH-1]
gi|42550792|gb|EAA73635.1| conserved hypothetical protein [Gibberella
zeae PH-1]
Length = 1051
Score = 872 bits (2254), Expect = 0.0
Identities = 483/1060 (45%), Positives = 659/1060 (61%), Gaps = 36/1060 (3%)
Frame = -1
Query: 3084 RASLICRLASPSRINAIRNASSGKSHISASTLVQHRNQSVAAAVKHEP------FLNGSS 2923
R S AS S ++A SS K S L ++ A + P FL+GS+
Sbjct: 18 RCSAASSTASISTLSA--RTSSWKLAASRRPLAVGARRTYATSATSSPPDPNDNFLSGST 75
Query: 2922 SIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAAAQV 2743
+ YI++MY W QDP SVH SW YF+N+E G G P
Sbjct: 76 ASYIDEMYMQWRQDPESVHVSWQVYFKNMEGGEMPISQAFQPPPNLVPGMTGGVP----- 130
Query: 2742 TTSSAPATRLDTNASVQSISD---HLKIQLLIRSYQTRGHNIADLDPLGINSAD----LD 2584
RL N +++ SD HLK+QLL+R+YQ+RGH+ A +DPLGI +
Sbjct: 131 --------RLSGNLAMEDGSDVTNHLKVQLLVRAYQSRGHHTAKIDPLGIRGTNDAKGFA 182
Query: 2583 DTIPPELELSFYGLGERDLDREFLLPPTTFISEKKS----LTLREILQRLKDIYCTSTGV 2416
+ P EL L YG E+D+D E+ L P K+ +TLREI+ + IYC S GV
Sbjct: 183 NIKPKELTLEHYGFTEKDMDTEYTLGPGILPRFKRDGREKMTLREIVDACERIYCGSFGV 242
Query: 2415 EYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGL 2236
E++H+ + ++ DW+R R E P + S D+K+ + RLI S+ FE FLA K+P++KRFGL
Sbjct: 243 EFIHIPDRDKCDWLRERLEVPNPFKYSVDEKRRVLDRLIWSSSFESFLATKYPNDKRFGL 302
Query: 2235 EGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEPA 2059
EGCE L+P MK +ID S GV VIGMPHRGRLNVL+NV R+P +I S+F+ T
Sbjct: 303 EGCETLVPGMKALIDRSVDYGVKDIVIGMPHRGRLNVLSNVVRKPNESIFSEFAGTSGGE 362
Query: 2058 DEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKC 1879
DEGSGDVKYHLG+ ER S K V++++VANPSHLEA DPVV+GK RA Y DEK
Sbjct: 363 DEGSGDVKYHLGMNFERPT-PSGKRVQLSLVANPSHLEAEDPVVLGKTRAIQHYNNDEKT 421
Query: 1878 DRT-MAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSP 1702
RT M++LLHGDAAFA QG+V E LP+++T G IH+VVNNQIGFTTDPR +RS+
Sbjct: 422 HRTAMSVLLHGDAAFAAQGIVYECLGFHSLPAFSTGGTIHLVVNNQIGFTTDPRFARSTA 481
Query: 1701 YCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEP 1522
YCTD+ + + P+FHVN DD EAV VC +AADWR F+ DV++DL CYR++GHNE D+P
Sbjct: 482 YCTDIAKAIDAPVFHVNADDVEAVNFVCQLAADWRAEFQHDVVIDLNCYRKYGHNETDQP 541
Query: 1521 MFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYV 1342
FTQPLMY+RI + ++ Y K++ EG ++ V+E +LE+++ ++ T
Sbjct: 542 SFTQPLMYKRINAKEPQIDIYVNKLIEEGSFSKADVEEHKQWVWGMLEESFTKSKDYT-P 600
Query: 1341 RNRDWLDSPWDDFFKKR----DPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTL 1174
+++W S W+ F + + L T PEGF +HR L+R L
Sbjct: 601 TSKEWTTSAWNGFKSPKELATEVLATNETNVKSTTLEHIGNAIGSVPEGFQVHRNLKRIL 660
Query: 1173 KGR-QQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQK 997
R + +++ ++D+ EALAFG+L+ EG HVR+SGQDV+RGTFS RH V HDQ+ +
Sbjct: 661 SNRTKSVVEGKNIDFPTAEALAFGTLVTEGYHVRVSGQDVERGTFSQRHAVFHDQETED- 719
Query: 996 IYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCII 817
+ PL +LS+ QG++ + NSSLSE+ LGFE GYS+ P++LV+WEAQFGDF+N AQCII
Sbjct: 720 THTPLQNLSQDQGKFVISNSSLSEFGALGFEYGYSLSSPHALVMWEAQFGDFANNAQCII 779
Query: 816 DQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGT 637
DQFI+SG+ KW++++GLVM LPHGY+G GPEHSS R ER+LQ+ NED + G
Sbjct: 780 DQFIASGEVKWMQRTGLVMSLPHGYDGQGPEHSSGRLERYLQLSNED-----PREFPTGE 834
Query: 636 FEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQ 457
+Q D N +A T+PAN++H LRRQ+ +RKP ++F KSLLRHP+ARS +E F
Sbjct: 835 KLVRQHQDCNMQIAYFTSPANLFHALRRQMHRQYRKPLIIFFSKSLLRHPLARSDIEAFT 894
Query: 456 -SGSNFQRVIP----ETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKEN--DVALVR 298
+ FQ +IP ETGA ++P ++RVV CTG+V+ A K+ N +VA R
Sbjct: 895 GENAGFQWIIPDPEHETGA-IKSPDQIERVVLCTGQVW---AALHKYRADNNIDNVAFTR 950
Query: 297 VEQLSPFPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLLSIDGRATK--- 130
+EQL+PFP+ +++ +Y A+ I+W QEE N GAWSF QPRI +LL+ T+
Sbjct: 951 IEQLNPFPWQQLKENLDQYPNAKTIVWCQEEPLNAGAWSFTQPRIETLLNNTEHHTRKHV 1010
Query: 129 -YAGRLPSSSPATGNKFTHMQEQKEMMSKVFGVPKSKLEG 13
YAGR PS+S ATG K H +E+K+ + F V + KL+G
Sbjct: 1011 MYAGRNPSASVATGLKNVHTKEEKDFLEMAFTVKQDKLKG 1050
>gi|50425085|ref|XP_461134.1| unnamed protein product [Debaryomyces
hansenii]
gi|49656803|emb|CAG89517.1| unnamed protein product [Debaryomyces
hansenii CBS767]
Length = 997
Score = 870 bits (2249), Expect = 0.0
Identities = 463/993 (46%), Positives = 634/993 (63%), Gaps = 20/993 (2%)
Frame = -1
Query: 2958 AVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYA 2779
A + FL +++ YI++MY AW DPSSVH SW+AYF+N+E
Sbjct: 27 ATGQDSFLLSNNANYIDEMYAAWKHDPSSVHISWNAYFKNIESSNVPPSKAFTAPPTIIP 86
Query: 2778 GALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGIN 2599
G AA S+P + + HLK+QLL+R+YQ RGH A +DPLGI+
Sbjct: 87 TVAG---GAAGFVPGSSPTN--------EDVVTHLKVQLLVRAYQVRGHQKAKIDPLGIS 135
Query: 2598 SADLDDTIPPELELSFYGLGERDLDREFLLPPTTFI----SEKKSLTLREILQRLKDIYC 2431
D +D +P EL L YG E D+D++ L P KKSLTLREI+ + +YC
Sbjct: 136 FGD-NDVVPKELTLEHYGFTEADMDKQITLGPGILPRFAEGGKKSLTLREIISNCERLYC 194
Query: 2430 TSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSE 2251
S GVEY+H+ + EQ DW+R R E P + S D+K+ + R+I S FE FLA K+P++
Sbjct: 195 QSYGVEYIHIPSKEQCDWLRERIEIPEPYKYSPDEKRQILDRVIWSCSFESFLASKFPND 254
Query: 2250 KRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFST 2071
KRFGLEG E ++P MK +ID+S GV+ VIGMPHRGRLN+L+NV R+P +I S+F+
Sbjct: 255 KRFGLEGAESVVPGMKAMIDTSVEFGVEDIVIGMPHRGRLNMLSNVVRKPNESIFSEFTG 314
Query: 2070 LEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAG 1891
DEGSGDVKYHLG+ R S K+V +++VANPSHLE+ D VV+GK RA Y
Sbjct: 315 SREFDEGSGDVKYHLGMNYARPTT-SGKHVNLSLVANPSHLESEDGVVLGKTRAIQQYKN 373
Query: 1890 D-EKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSS 1714
D + + M+ILLHGDAAF+GQGVV ET L +LP Y+T G IHI+VNNQIGFTTDPR +
Sbjct: 374 DIGEYKKAMSILLHGDAAFSGQGVVYETMGLANLPDYSTGGTIHIIVNNQIGFTTDPRFA 433
Query: 1713 RSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNE 1534
RS+ Y +D+ + + PIFHVN DD EA + + N+AA+WR TF DVI+DLV YR+HGHNE
Sbjct: 434 RSTLYPSDIAKSINAPIFHVNADDVEANIFIFNLAAEWRATFHTDVIIDLVGYRKHGHNE 493
Query: 1533 LDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQK 1354
D+P FTQPLMYQ+I + K ++ Y ++++ EG ++ + E +IL++++ +++
Sbjct: 494 TDQPAFTQPLMYQKIAEKKPVIDYYTKQLIEEGTFTKEDIDEHKKWVWNILDESFSKSKE 553
Query: 1353 VTYVRNRDWLDSPWDDFFKKRDPLKLPS-------TGXXXXXXXXXIGKFSQYPEGFNLH 1195
+R+WL + W+DF + P +L + T S+ PEGF +H
Sbjct: 554 YQST-SREWLTTAWEDF---KSPKELATEVLPHLPTAVEEDTLKKIGTAISEAPEGFEVH 609
Query: 1194 RGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLH 1018
R L+R L R++ ++ +DW+ GEALA+GSL EG HVR+SGQDV+RGTFS RH VLH
Sbjct: 610 RNLKRILNARKKSVETGEGIDWSTGEALAYGSLALEGYHVRVSGQDVERGTFSQRHAVLH 669
Query: 1017 DQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFS 838
DQ +Q Y PLN+LSE QG + +CNSSLSEY V+ FE GYS+ P++LV WEAQFGDF+
Sbjct: 670 DQSSEQ-TYTPLNNLSEDQGAFVICNSSLSEYGVMSFEYGYSLTSPDALVQWEAQFGDFA 728
Query: 837 NTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLE 658
NTAQ I+DQFIS+ +SKW ++SGLV+ LPHGY+G GPEHSS R ER+LQ+CNED
Sbjct: 729 NTAQVIVDQFISAAESKWKQRSGLVLSLPHGYDGQGPEHSSGRIERYLQLCNEDQRYFPS 788
Query: 657 KIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMAR 478
E +Q D N VA TTPANI+HLLRRQ+ FRKP V+F K LLRHP+A+
Sbjct: 789 PELLE-----RQHQDANMQVAYPTTPANIFHLLRRQMHRQFRKPLVLFFSKQLLRHPLAK 843
Query: 477 SPVEDFQSGSNFQRVI--PETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVAL 304
S + +F S+FQ +I PE G D+KRV+ C+G+V+ + R + ++ A
Sbjct: 844 SELSEFTGESHFQWIIEDPELGKSINAKEDIKRVILCSGQVFTALHKKRADI-EDKSTAF 902
Query: 303 VRVEQLSPFPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLL----SIDGR 139
+++EQL PFP+ ++ Y E ++W QEE NMG++S+ PRI ++L +
Sbjct: 903 IKIEQLHPFPFAQLRDALDSYPALEDLVWCQEEPLNMGSYSYSAPRIATVLENTEKHKDK 962
Query: 138 ATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVF 40
+ +YAGR PS+S A G K H E++E + +VF
Sbjct: 963 SLRYAGRDPSASVAAGTKAMHNSEEEEFLKEVF 995
>gi|46431876|gb|EAK91398.1| hypothetical protein CaO19.6165 [Candida
albicans SC5314]
Length = 996
Score = 868 bits (2242), Expect = 0.0
Identities = 459/987 (46%), Positives = 636/987 (63%), Gaps = 18/987 (1%)
Frame = -1
Query: 2946 EPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALG 2767
+ FL GS+S Y+++MYEAW QDPSSVH SW+AYF+N+E A
Sbjct: 35 DSFLQGSNSNYVDEMYEAWRQDPSSVHASWNAYFKNIENDNIPPSK-----------AFQ 83
Query: 2766 VSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADL 2587
P + A + + + HLK+QLL+R+YQ RGH A +DPLGI+ D
Sbjct: 84 APPTIVPTVSGGAAGFYPGQSPISEDVVTHLKVQLLVRAYQVRGHQKAKIDPLGISFGD- 142
Query: 2586 DDTIPPELELSFYGLGERDLDREFLLPPTTFI----SEKKSLTLREILQRLKDIYCTSTG 2419
+ T+P EL L +YG E+DL +E L P KKS+TL+EI+ + YC+S G
Sbjct: 143 NTTVPKELTLDYYGFTEQDLAKEITLGPGILPRFAQGGKKSMTLKEIINFCEKTYCSSYG 202
Query: 2418 VEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFG 2239
VEY+H+ + EQ DW+R R E P+ + S DQK+ + RLI +T FE FL+ K+P++KRFG
Sbjct: 203 VEYVHIPSKEQCDWLRDRIEVPQPFKYSPDQKRQILDRLIWATSFESFLSSKFPNDKRFG 262
Query: 2238 LEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPA 2059
LEG E ++P MK +ID+S GV+ VIGMPHRGRLN+L+NV R+P +I S+F+ +
Sbjct: 263 LEGAEAVVPGMKALIDTSVEYGVEDVVIGMPHRGRLNMLSNVVRKPNESIFSEFTGSKEF 322
Query: 2058 DEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGD-EK 1882
DEGSGDVKYHLG+ R S K+V +++VANPSHLEA D VV+GK RA Y D
Sbjct: 323 DEGSGDVKYHLGMNYARPTT-SGKHVNLSIVANPSHLEAEDGVVLGKTRAIQQYKQDIGS 381
Query: 1881 CDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSP 1702
+ MA+LLHGDAAFAGQGVV ET +LP+Y+T G IH++VNNQIGFTTDPR +RS+
Sbjct: 382 FKKAMAVLLHGDAAFAGQGVVYETMGFANLPAYSTGGTIHVIVNNQIGFTTDPRFARSTL 441
Query: 1701 YCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEP 1522
Y +D+ + + PIFHVN DD EA V N+AA+WR T+ D I+D+V YR+HGHNE D+P
Sbjct: 442 YPSDIAKAIDAPIFHVNADDVEACTFVFNLAAEWRATYHTDCIIDVVGYRKHGHNETDQP 501
Query: 1521 MFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYV 1342
FTQPLMYQ I + + ++ Y++++++EG + +KE +ILED ++ A++
Sbjct: 502 SFTQPLMYQEIAKKNSVIDIYEKQLIDEGTFTAEDIKEHKQWVWNILEDNFKKAKEYK-P 560
Query: 1341 RNRDWLDSPWDDFFKKRDPLKLPS-------TGXXXXXXXXXIGKFSQYPEGFNLHRGLE 1183
+R+WL +PW+DF + P +L + T S+ PEGF +HR L+
Sbjct: 561 TSREWLTTPWEDF---KSPKELATEVLPHLPTAVDEATLKKIGNAISETPEGFEVHRNLK 617
Query: 1182 RTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKV 1006
R L R++ ++ +D+A GEALA+GSL EG HVR+SGQDV+RGTFS RH VLHDQ
Sbjct: 618 RILNARKKSVETGEGIDYATGEALAYGSLALEGYHVRVSGQDVERGTFSQRHAVLHDQN- 676
Query: 1005 DQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQ 826
+ ++ PL++LSE QG + + NSSLSEY VLGFE GYS+ P++LV WEAQFGDF+NTAQ
Sbjct: 677 SESVWTPLSNLSEDQGAFNISNSSLSEYGVLGFEYGYSLTSPDALVEWEAQFGDFANTAQ 736
Query: 825 CIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAF 646
+IDQF++ +SKW ++SG+V+ LPHGY+G GPEHSS+R ER+LQ+CNED
Sbjct: 737 VVIDQFVAGAESKWKQRSGVVLSLPHGYDGQGPEHSSSRLERYLQLCNEDQRFFPSPEKL 796
Query: 645 EGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVE 466
E +Q D N VA TTPAN++HLLRRQ+ FRKP ++ KSLLRHP+ARS +
Sbjct: 797 E-----RQHQDCNMQVAYPTTPANVFHLLRRQMHRQFRKPLILVFSKSLLRHPLARSNLS 851
Query: 465 DFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQL 286
+F S+FQ +I + + +VKRVV TG+VY + R + + A +++EQL
Sbjct: 852 EFTGDSHFQWIIEDV---LGDKSEVKRVVLLTGQVYAALHKKRASL-DDKSTAFIKIEQL 907
Query: 285 SPFPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLLSIDGR----ATKYAG 121
PFPY ++ +Y E ++W QEE NMGA++F PR+ ++L + +YAG
Sbjct: 908 HPFPYAQLRDALNEYPNLEDLVWTQEEPLNMGAYNFAAPRVEAVLGETQKYKDLKLRYAG 967
Query: 120 RLPSSSPATGNKFTHMQEQKEMMSKVF 40
R PS+S A G+K H+ E++E + + F
Sbjct: 968 RDPSASVAAGSKAMHVAEEEEFLEETF 994
>gi|11252290|pir||T47680 probable oxoglutarate dehydrogenase
(lipoamide) (EC 1.2.4.2) E1 chain - Arabidopsis thaliana
gi|7076784|emb|CAB75899.1| 2-oxoglutarate dehydrogenase, E1
subunit-like protein [Arabidopsis thaliana]
Length = 1009
Score = 861 bits (2225), Expect = 0.0
Identities = 467/998 (46%), Positives = 631/998 (62%), Gaps = 28/998 (2%)
Frame = -1
Query: 2946 EPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALG 2767
+ FL+G+SS+Y+E++ AW DP+SV SWD +FRN + G
Sbjct: 64 DSFLDGTSSVYLEELQRAWEADPNSVDESWDNFFRN------------------FVGQAA 105
Query: 2766 VSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADL 2587
SP S Q+I + +++ LL+R+YQ GH A LDPLG+ +
Sbjct: 106 TSP-----------------GISGQTIQESMRLLLLVRAYQVNGHMKAKLDPLGLEQRE- 147
Query: 2586 DDTIPPELELSFYGLGERDLDREFLL---PPTTFISEKKSL-TLREILQRLKDIYCTSTG 2419
IP +L+L+ YG E DLDREF L + F+SE + + TLR IL RL+ YC + G
Sbjct: 148 ---IPEDLDLALYGFTEADLDREFFLGVWQMSGFMSENRPVQTLRSILTRLEQAYCGNIG 204
Query: 2418 VEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFG 2239
EYMH+ + ++ +W+R + E P + ++++V+ RL ST+FE FLA KW + KRFG
Sbjct: 205 FEYMHIADRDKCNWLREKIETPTPWRYNRERREVILDRLAWSTQFENFLATKWTTAKRFG 264
Query: 2238 LEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEP 2062
LEG E LIP MK++ D ++ LGV+S VIGM HRGRLNVL NV R+PL I S+FS + P
Sbjct: 265 LEGGESLIPGMKEMFDRAADLGVESIVIGMSHRGRLNVLGNVVRKPLRQIFSEFSGGIRP 324
Query: 2061 ADE----GSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYA 1894
DE G+GDVKYHLG +R R +K + +++VANPSHLEA D VV+GK RA+ +Y+
Sbjct: 325 VDEVGYTGTGDVKYHLGTSYDRPTRGGKK-IHLSLVANPSHLEAADSVVVGKTRAKQYYS 383
Query: 1893 GDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSS 1714
D + + IL+HGD +FAGQGVV ET +L LP+YTT G IHIVVNNQ+ FTTDPR+
Sbjct: 384 NDLDRTKNLGILIHGDGSFAGQGVVYETLHLSALPNYTTGGTIHIVVNNQVAFTTDPRAG 443
Query: 1713 RSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNE 1534
RSS YCTDV + + PIFHVN DD EAV+H C +AA+WR+TF DV+VDLVCYRR GHNE
Sbjct: 444 RSSQYCTDVAKALSAPIFHVNGDDVEAVVHACELAAEWRQTFHSDVVVDLVCYRRFGHNE 503
Query: 1533 LDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQK 1354
+DEP FTQP MY+ IK + L+ Y +K+L G ++Q + K +IL + + A K
Sbjct: 504 IDEPSFTQPKMYKVIKNHPSTLQIYHKKLLECGEVSQQDIDRIQEKVNTILNEEFV-ASK 562
Query: 1353 VTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTL 1174
+ RDWL + W F ++ +TG S PE F HR +++
Sbjct: 563 DYLPKKRDWLSTNWAGFKSPEQISRVRNTGVKPEILKTVGKAISSLPENFKPHRAVKKVY 622
Query: 1173 KGRQQMLKD-NSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQK 997
+ R QM++ +DWA EALAF +L+ EG HVRLSGQDV+RGTFSHRH VLHDQ+ ++
Sbjct: 623 EQRAQMIESGEGVDWALAEALAFATLVVEGNHVRLSGQDVERGTFSHRHSVLHDQETGEE 682
Query: 996 IYNPLNDLSEGQGE--YTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQC 823
Y PL+ L Q +TV NSSLSE+ VLGFELGYSM PNSLV+WEAQFGDF+N AQ
Sbjct: 683 -YCPLDHLIMNQDPEMFTVSNSSLSEFGVLGFELGYSMESPNSLVLWEAQFGDFANGAQV 741
Query: 822 IIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI--DLEKIA 649
I DQFISSG++KW+RQ+GLVMLLPHGY+G GPEHSSAR ER+LQM +++ + D+E
Sbjct: 742 IFDQFISSGEAKWLRQTGLVMLLPHGYDGQGPEHSSARLERYLQMSDDNPYVIPDMEPTM 801
Query: 648 FEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPV 469
+Q+ + NW + N TTPAN +H+LRRQ+ FRKP +V +PK+LLRH +S +
Sbjct: 802 ------RKQIQECNWQIVNATTPANYFHVLRRQIHRDFRKPLIVMAPKNLLRHKDCKSNL 855
Query: 468 EDF----------QSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKE 319
+F + G+ F+R+I + S ++R+V C+GKVYY++ RK VG
Sbjct: 856 SEFDDVQGHPGFDKQGTRFKRLIKDQNDHSDLEEGIRRLVLCSGKVYYELDDERKKVG-A 914
Query: 318 NDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRI----NSLLS 151
DVA+ RVEQL PFPYDL+Q+E ++Y +E NMGA+S++ PR+ S+
Sbjct: 915 TDVAICRVEQLCPFPYDLIQRELKRY--------PKEAMNMGAFSYISPRLWTAMRSVNR 966
Query: 150 IDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFG 37
D KY GR PS++ ATG H++EQ ++ K G
Sbjct: 967 GDMEDIKYVGRGPSAATATGFYTFHVKEQAGLVQKAIG 1004
>gi|19112564|ref|NP_595772.1| 2-oxoglutarate dehydrogenase e1
component [Schizosaccharomyces pombe]
gi|7489939|pir||T40412 2-oxoglutarate dehydrogenase e1 component -
fission yeast (Schizosaccharomyces pombe)
gi|3417411|emb|CAA20299.1| SPBC3H7.03c [Schizosaccharomyces pombe]
Length = 1009
Score = 859 bits (2220), Expect = 0.0
Identities = 464/1033 (44%), Positives = 649/1033 (61%), Gaps = 28/1033 (2%)
Frame = -1
Query: 3063 LASPSRINAIRNASSGKSHISASTLVQHRNQSVAAAVKH-EPFLNGSSSIYIEQMYEAWL 2887
+ S ++ A+R ++ ++ T + Q+ A + + FL G ++ Y+++MY+AW
Sbjct: 5 IPSSAKARALRRSAVTAYRLNRLTCLSSLQQNRTFATQPTDDFLTGGAADYVDEMYDAWK 64
Query: 2886 QDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAAA----QVTTSSAPAT 2719
+DP+SVH SW AYF+NV+ GVSP+ A + + T
Sbjct: 65 KDPNSVHASWQAYFKNVQER-------------------GVSPSKAFQAPPLLDYADSYT 105
Query: 2718 RLDT------NASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELEL 2557
LD+ N + + ++K+QLL+R+YQ+RGH++A LDPLGIN ++ P EL L
Sbjct: 106 ALDSSLINGNNYADIDVGIYMKVQLLVRAYQSRGHHLAKLDPLGIN---VNHNRPSELTL 162
Query: 2556 SFYGLGERDLDREFLLPPTTFIS----EKKSLTLREILQRLKDIYCTSTGVEYMHLNNLE 2389
YG E DL+R L P + +K++TLREI++ + IYC S VE+ H+++ +
Sbjct: 163 EHYGFTESDLNRTIHLGPGILPNFREAGRKTMTLREIVETCEKIYCGSFAVEFTHISSRK 222
Query: 2388 QQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPA 2209
+ +WI E P SHDQK ++F RL + FE FL K+P++KRFGLEGCE ++P
Sbjct: 223 RSNWILSHLETPTPFRYSHDQKIMIFDRLSWADSFERFLFTKFPNDKRFGLEGCEAMVPG 282
Query: 2208 MKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQF-STLEPADEGSGDVKY 2032
MK +ID S G+ + VIGM HRGRLN+L N+ R+P I S+F T +P DEGSGDVKY
Sbjct: 283 MKALIDRSVDEGISNIVIGMAHRGRLNLLHNIVRKPAQAIFSEFRGTQDPDDEGSGDVKY 342
Query: 2031 HLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKC-DRTMAILL 1855
HLG+ +R S K V +++VANPSHLEA DPVV+GKVRA Y DE +++M IL+
Sbjct: 343 HLGMNYQRPT-PSGKRVSLSLVANPSHLEAEDPVVLGKVRAIQHYTSDEASHEQSMGILI 401
Query: 1854 HGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVV 1675
HGDAAFA QGVV ETF L LP Y+T G +HIV+NNQIGFTTDPR +RS+PYCTD+ + +
Sbjct: 402 HGDAAFAAQGVVYETFGLHALPGYSTGGTVHIVINNQIGFTTDPRFARSTPYCTDIAKSM 461
Query: 1674 GCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQ 1495
PIFHVN DD EAV +C +AADWRK FK DV+VD+VCYRRHGHNE D+P FTQP MY+
Sbjct: 462 EAPIFHVNGDDVEAVTFICQLAADWRKAFKTDVVVDIVCYRRHGHNETDQPSFTQPRMYK 521
Query: 1494 RIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSP 1315
I + + Y +++L E ++ V + + ILE ++E+++ +R+WL +P
Sbjct: 522 AIAKHPPTFKIYTQQLLQEKTVSKAEVDAQEKRVWDILESSFESSKNYK-SDHREWLSNP 580
Query: 1314 WDDFFKKRDPLK--LPS--TGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKD 1147
W F +D + LPS TG PEGF+ HR L+R L R + +
Sbjct: 581 WVGFASPKDLMTKILPSYPTGVNIDTLKQIGKALYTLPEGFDAHRNLKRILNNRNKSISS 640
Query: 1146 -NSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLS 970
+D EALAFG+LL+EG HVR+SGQDV+RGTFS RH VLHDQ + +Y PLN LS
Sbjct: 641 GEGIDMPTAEALAFGTLLEEGHHVRVSGQDVERGTFSQRHAVLHDQS-SENVYIPLNHLS 699
Query: 969 EGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQS 790
Q + + NSSLSEY VLGFE GYS+ PN+LV+WEAQFGDF+N AQCIIDQFI++G++
Sbjct: 700 PNQASFVIRNSSLSEYGVLGFEYGYSLSSPNALVVWEAQFGDFANNAQCIIDQFIAAGET 759
Query: 789 KWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLH-D 613
KW++++G+V+ LPHGY+G GPEHSSAR ER+LQ+CNED F + Q+ H D
Sbjct: 760 KWLQRTGIVLSLPHGYDGQGPEHSSARMERYLQLCNEDPR------EFPSEEKLQRQHQD 813
Query: 612 TNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRV 433
N T P+ +H LRR + FRKP V+F KSLLRHP ARS +++F F+ +
Sbjct: 814 CNIQAIYVTKPSQYFHALRRNIHRQFRKPLVIFFSKSLLRHPAARSTIDEFDEKHGFKLI 873
Query: 432 IPET--GAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQ 259
+ E G P +++++ C+G+V+ + AR+ K +++A+ RVEQL PF + +
Sbjct: 874 LEEEEHGKSILPPEKIEKLIICSGQVWVALSKAREE-NKIDNIAITRVEQLHPFGWKQMA 932
Query: 258 QECRKYQG-AEILWAQEEHKNMGAWSFVQPRINSLLSIDGR--ATKYAGRLPSSSPATGN 88
+Y EI+W QEE N GAW++++PRI ++L GR +YAGR PS+S A GN
Sbjct: 933 ANISQYPNLKEIIWCQEEPLNAGAWTYMEPRIYTILKHLGRDLPVRYAGRPPSASVAAGN 992
Query: 87 KFTHMQEQKEMMS 49
K H+ EQ++ ++
Sbjct: 993 KQQHLAEQEQFLN 1005
>gi|50288623|ref|XP_446741.1| unnamed protein product [Candida
glabrata]
gi|49526049|emb|CAG59668.1| unnamed protein product [Candida glabrata
CBS138]
Length = 1011
Score = 848 bits (2191), Expect = 0.0
Identities = 456/1001 (45%), Positives = 636/1001 (62%), Gaps = 21/1001 (2%)
Frame = -1
Query: 2979 RNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXX 2800
R +V + F+N +++ YI++MY+AW QDPSSVH SW+AYF+N++
Sbjct: 29 RATAVRTYASQDNFVNTTNAAYIDEMYQAWQQDPSSVHASWNAYFKNMKDLKIPASQAFQ 88
Query: 2799 XXXXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIAD 2620
G T AP + L + +++S HLK+QLL R+YQ RGH A
Sbjct: 89 APPILLGSPQG---------THEAPLSTLSGSNIDENVSVHLKVQLLCRAYQVRGHLKAH 139
Query: 2619 LDPLGIN-SADLDDTIPPELELSFYGLGERDLDREFLLPP---TTFISE-KKSLTLREIL 2455
+DPLGI+ ++ + TIP EL L +YG ERDLDRE L P F + KKS+TLREI+
Sbjct: 140 IDPLGISFGSNKNATIPKELTLDYYGFTERDLDREINLGPGILPRFARDGKKSMTLREII 199
Query: 2454 QRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEF 2275
+ ++ +YCTS G+EY H+ + E+ +W+R R E P + + DQK+ + RL +T FE F
Sbjct: 200 EHMEKLYCTSYGIEYTHIPSKEKCEWLRERIEIPTPYQYTVDQKRQILDRLTWATSFESF 259
Query: 2274 LAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLA 2095
L+ K+P+EKRFGLEG E ++P +K +ID S +GV+ V+GM HRGRLNVL+NV R+P
Sbjct: 260 LSTKFPNEKRFGLEGLEAVVPGIKTLIDRSVEMGVEDVVLGMAHRGRLNVLSNVVRKPNE 319
Query: 2094 TILSQFSTLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGK 1918
+I S+F D EGSGDVKYHLG+ +R S K V +++VANPSHLEA DPVV+G+
Sbjct: 320 SIFSEFQGTTKKDVEGSGDVKYHLGMNYQRPTT-SGKYVNLSLVANPSHLEAQDPVVLGR 378
Query: 1917 VRAEAFYAGD-EKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQI 1741
R+ D E + +A+LLHGDAAFAGQGVV ET +LP Y+T G IHI+ NNQI
Sbjct: 379 TRSILHAKNDLETKSKALAVLLHGDAAFAGQGVVYETMGFVNLPEYSTGGTIHIITNNQI 438
Query: 1740 GFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLV 1561
GFTTDPR SRS+PY +D+ + + PIFHVN +D EAV ++ +AA+WR+TF D I+D+V
Sbjct: 439 GFTTDPRFSRSTPYPSDLAKAIDAPIFHVNANDVEAVTYIFGLAAEWRQTFHTDAIIDVV 498
Query: 1560 CYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSIL 1381
+R+HGHNE D+P FTQPLMY++I +T + ++ Y +K+L EG ++ ++E +
Sbjct: 499 GWRKHGHNETDQPSFTQPLMYKQIAKTPSVIDVYTDKLLKEGSFSKSDIEEHKKWVWGMF 558
Query: 1380 EDAYENAQKVTYVRN-RDWLDSPWDDFFKKR----DPLKLPSTGXXXXXXXXXIGKFSQY 1216
E+A+E A+ YV R+WL + W+DF + + L T S +
Sbjct: 559 EEAFEKAK--DYVPTPREWLTAAWEDFKSPKELATEILPHEPTKVSEDILKNIGKTISSW 616
Query: 1215 PEGFNLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFS 1039
PE F +HR L+R L R + ++ +DWA GEALA+GSL+ EG +VR+SG+DV+RGTFS
Sbjct: 617 PENFEVHRNLKRILNQRGKSVETGEGIDWATGEALAYGSLVLEGHNVRVSGEDVERGTFS 676
Query: 1038 HRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWE 859
RH VLHDQ + Y PL +LS+ Q ++T+ NSSLSEY V+GFE GYS+ P +L++WE
Sbjct: 677 QRHSVLHDQ-ASEATYTPLKNLSDKQADFTIANSSLSEYGVMGFEYGYSLTSPENLIVWE 735
Query: 858 AQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNE 679
AQFGDF+NTAQ IIDQFI+ G+ KW ++SGLV+ LPHGY+G GPEHSS R ERFLQM NE
Sbjct: 736 AQFGDFANTAQVIIDQFIAGGEQKWKQRSGLVLSLPHGYDGQGPEHSSGRLERFLQMANE 795
Query: 678 DDEIDLEKIAFEGTFEAQQLH-DTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKS 502
D F + Q+ H D N+ V TTPAN++H+LRRQ FRKP V+F K
Sbjct: 796 DPRY------FPSPEKLQRQHQDCNYQVVYPTTPANLFHILRRQQHRQFRKPLVLFFSKQ 849
Query: 501 LLRHPMARSPVEDFQSGSNFQRVIP--ETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHV 328
LLRHP+ARS + +F GS FQ +I E G + K++V +G+VY + R+ +
Sbjct: 850 LLRHPLARSNLSEFTEGS-FQWIIEDVEHGKAIGTKEETKKLVLMSGQVYTALHKKREQL 908
Query: 327 GKENDVALVRVEQLSPFPYDLVQQECRKYQG-AEILWAQEEHKNMGAWSFVQPRINSLL- 154
G + A +++E+L PFP+ ++ Y EI+W QEE NMG+W++V PR+ ++L
Sbjct: 909 G-DKTTAFLKIEELHPFPFAQLRDTLNSYPNLEEIVWCQEEPLNMGSWNYVAPRLQTVLK 967
Query: 153 ---SIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVF 40
+Y GR PS + A GNK H+ E++ + VF
Sbjct: 968 ETEQYKDNVVRYCGRSPSGAVAAGNKKLHLAEEEAFLKDVF 1008
>gi|50310525|ref|XP_455282.1| unnamed protein product [Kluyveromyces
lactis]
gi|49644418|emb|CAG97990.1| unnamed protein product [Kluyveromyces
lactis NRRL Y-1140]
Length = 1017
Score = 829 bits (2141), Expect = 0.0
Identities = 449/997 (45%), Positives = 625/997 (62%), Gaps = 21/997 (2%)
Frame = -1
Query: 2964 AAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXA 2785
+ A + FL+ +++ YI++MYEAW +DP+SVH SWDAYF+N+
Sbjct: 38 SGASSTDNFLSTTNASYIDEMYEAWQKDPTSVHVSWDAYFKNMGNLNIPASSAFTAPPTL 97
Query: 2784 YAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLG 2605
G P Q + +D Q I+ HLK+QLL R+YQ RGH A +DPL
Sbjct: 98 IPIPTG--PGVPQDILIGGSLSGVD-----QDITTHLKVQLLCRAYQVRGHQKAHIDPLQ 150
Query: 2604 INSAD-LDDTIPPELELSFYGLGERDLDREFLLPPTTFI----SEKKSLTLREILQRLKD 2440
I+ D +P EL L YG E+DLDR+ L P +K++ LREI+ L+
Sbjct: 151 ISFGDDKSKPLPRELTLEHYGFTEKDLDRDITLGPGILPRFSRDGRKTMKLREIIAALEK 210
Query: 2439 IYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKW 2260
+YC+ G+EY+H+ + EQ +W+R R E P+ + DQK+ + RL +T FE FL+ K+
Sbjct: 211 LYCSGYGIEYIHIPSKEQCEWLRERIEIPQPYNYTVDQKRQILDRLTWATSFETFLSTKF 270
Query: 2259 PSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQ 2080
P++KRFGLEG E ++P +K +ID S LGV+ V+GM HRGRLNVL+NV R+P +I S+
Sbjct: 271 PNDKRFGLEGLEGVVPGIKTLIDRSVELGVEDVVLGMAHRGRLNVLSNVVRKPNESIFSE 330
Query: 2079 FS-TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAE 1906
F ++ P + EGSGDVKYHLG+ +R S K V +++VANPSHLEA DPVV+G+ RA
Sbjct: 331 FKGSVAPEEYEGSGDVKYHLGMNYQRPTT-SGKYVNLSLVANPSHLEAADPVVLGRTRAI 389
Query: 1905 AFYAGD-EKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT 1729
F D K D+ +++LLHGDAAFA QG+V ET LP+Y+T G IH++ NNQIGFTT
Sbjct: 390 QFSKNDIGKYDKAISVLLHGDAAFAAQGIVYETMGFLHLPAYSTGGTIHVITNNQIGFTT 449
Query: 1728 DPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRR 1549
DPR +RS+ Y +D+G+ + PIFHVN +D EA+ + N+AA+WR TF D I+D+V +R+
Sbjct: 450 DPRFARSTLYPSDLGKTIDAPIFHVNANDVEALTFIFNLAAEWRATFHTDAIIDVVGWRK 509
Query: 1548 HGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAY 1369
HGHNE D+P FTQPLMYQ+I + K+ ++ Y EK+++EG +Q + E + E+AY
Sbjct: 510 HGHNETDQPSFTQPLMYQKISKQKSVIDVYTEKLVSEGSFTKQDIDEHKKWVWGLFEEAY 569
Query: 1368 ENAQKVTYVRNRDWLDSPWDDFFKKR----DPLKLPSTGXXXXXXXXXIGKFSQYPEGFN 1201
E A K +R+WL + W+ F + + L T S +PE F
Sbjct: 570 EKA-KDYKPTSREWLTAAWEGFKSPKALATEILSHEPTVVDADTLKNIGKTISSWPENFE 628
Query: 1200 LHRGLERTLKGRQQMLKD-NSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHV 1024
+H+ L+R L R + ++ +DW+ GEALAFGSL+ EG HVR+SG+DV+RGTFS RH V
Sbjct: 629 VHKNLKRILTNRGKAVESGEGIDWSTGEALAFGSLVLEGNHVRVSGEDVERGTFSQRHAV 688
Query: 1023 LHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGD 844
LHDQK + Y PL LSE Q +T+CNSSLSEY +GFE GYS+ +P+ V+WEAQFGD
Sbjct: 689 LHDQK-SENTYTPLKHLSEKQANFTICNSSLSEYGCMGFEYGYSLTNPDYFVVWEAQFGD 747
Query: 843 FSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEID 664
F+NTAQ IIDQFI++G+ KW ++SGLV+ LPHGY+G GPEHSS R ERFLQ+ NED
Sbjct: 748 FANTAQVIIDQFIAAGEVKWKQRSGLVLSLPHGYDGQGPEHSSGRLERFLQLGNEDPRY- 806
Query: 663 LEKIAFEGTFEAQQLH-DTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHP 487
F + Q+ H D N+ + TTPAN++H+LRRQ FRKP +F K LLRHP
Sbjct: 807 -----FPSEEKLQRQHQDCNFQIVYPTTPANLFHILRRQQHRQFRKPLALFFSKQLLRHP 861
Query: 486 MARSPVEDFQSGSNFQRVIP--ETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKEND 313
+ARS + +F G FQ +I E G ++KRVV +G+VY + R+ + ++ +
Sbjct: 862 LARSNLNEFTEG-GFQWIIEDVELGKSIAPKEEIKRVVLLSGQVYTALHKKRETI-QDKN 919
Query: 312 VALVRVEQLSPFPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLLSIDGR- 139
A +++EQL PFPY ++ Y E I+W QEE NMG W++ QPR+ + L +
Sbjct: 920 TAFIKIEQLHPFPYAQLRDALNTYPNLEDIVWCQEEPLNMGGWAYAQPRLQTTLKETDKY 979
Query: 138 ---ATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFG 37
+YAGR PS S A G+K H E++ + +VFG
Sbjct: 980 KDAIIRYAGRNPSGSVAAGSKALHNAEEEAFLKEVFG 1016
>gi|45190976|ref|NP_985230.1| AER374Cp [Eremothecium gossypii]
gi|44984044|gb|AAS53054.1| AER374Cp [Eremothecium gossypii]
Length = 1004
Score = 825 bits (2132), Expect = 0.0
Identities = 453/995 (45%), Positives = 633/995 (63%), Gaps = 25/995 (2%)
Frame = -1
Query: 2946 EPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALG 2767
+ FL+ +++ YI++MY AW QDP+SVH SWDAYFRN++ AGA
Sbjct: 34 DTFLSSTNAAYIDEMYAAWQQDPASVHVSWDAYFRNMKNPSIA------------AGAAF 81
Query: 2766 VSPAAAQVTTSSAPATRLDTNASVQSISD---HLKIQLLIRSYQTRGHNIADLDPLGINS 2596
V+P V T++ P + + SD HLK+QLL R+YQ RGH A +DPLGI
Sbjct: 82 VAPPTL-VPTATDPGVPQHMPSVLGEDSDVLVHLKVQLLCRAYQVRGHQKAHIDPLGIAF 140
Query: 2595 AD-LDDTIPPELELSFYGLGERDLDREFLLPP---TTFISE-KKSLTLREILQRLKDIYC 2431
D ++P EL L Y E+DL+RE L P F + ++++ L EI+ L+ +YC
Sbjct: 141 GDDKSRSVPRELTLEHYNFSEKDLEREITLGPGILPRFARDGRRTMKLGEIVAALEKLYC 200
Query: 2430 TSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSE 2251
+S GVEY+H+ + EQ +W+R R E P+ + S ++KK +F RL +T FE FL+ K+P++
Sbjct: 201 SSYGVEYIHIPSREQCEWLRERIEIPKPYDYSAEEKKQIFDRLTWATSFESFLSSKFPND 260
Query: 2250 KRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS- 2074
KRFGLEG E ++P +K +ID S LG++ V+GM HRGRLNVL+NV R+P +I S+F
Sbjct: 261 KRFGLEGLEAVVPGIKTLIDRSVDLGIEDVVLGMAHRGRLNVLSNVVRKPNESIFSEFQG 320
Query: 2073 TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFY 1897
+ P+D EGSGDVKYHLG+ +R S K V +++VANPSHLEA +PVV+G+VRA
Sbjct: 321 SHTPSDYEGSGDVKYHLGMNYQRPTT-SGKYVNLSLVANPSHLEAENPVVLGRVRAIQHS 379
Query: 1896 AGDEKC-DRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPR 1720
D + M +LLHGDAAFA QGVV ET LP+Y+T G IH++ NNQIGFTTDPR
Sbjct: 380 KNDVGTFKKAMGVLLHGDAAFAAQGVVYETMGFLHLPAYSTGGTIHVITNNQIGFTTDPR 439
Query: 1719 SSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGH 1540
+RS+ Y +D+G+ + PIFHVN +D EAV + N+AA+WR TF D I+D+V +R+HGH
Sbjct: 440 FARSTSYPSDIGKTIDAPIFHVNANDIEAVNFIFNLAAEWRATFHTDAIIDVVGWRKHGH 499
Query: 1539 NELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEG-VANEQYVKEELTKYGSILEDAYEN 1363
NE D+P FTQPLMY++I + + ++ Y +K+L+EG + NEQ + +G + E+A+
Sbjct: 500 NETDQPSFTQPLMYKQIAKQPSVIDVYTKKLLDEGSMTNEQIDTHKKWVWG-LFEEAFSK 558
Query: 1362 AQKVTYVRNRDWLDSPWDDFFKKR----DPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLH 1195
A++ +R+WL + W++F + + L T S +P F +H
Sbjct: 559 AKEYK-PSSREWLTAAWENFKSSKELATEILPHNPTNVHSSTLKQIGSVLSSWPTDFEVH 617
Query: 1194 RGLERTLKGRQQMLKD-NSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLH 1018
R L+R L R + ++ +DW+ GEALAFG++L EG H+R+SG+DV+RGTFS RH VLH
Sbjct: 618 RNLKRILLNRGKSIESGEGIDWSTGEALAFGTMLMEGTHIRVSGEDVERGTFSQRHAVLH 677
Query: 1017 DQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFS 838
DQ + Y PL +S+ Q ++T+CNSSLSEY +GF+ GYS+ P+ V+WEAQFGDF+
Sbjct: 678 DQN-SENTYTPLKHVSKDQADFTICNSSLSEYGCIGFDYGYSLTSPDYFVMWEAQFGDFA 736
Query: 837 NTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLE 658
NTAQ IIDQFI+ ++KW ++SGLV+ LPHGY+G GPEHSS R ERFLQ+ NED
Sbjct: 737 NTAQVIIDQFIAGAETKWKQRSGLVLSLPHGYDGQGPEHSSGRLERFLQLTNEDPRY--- 793
Query: 657 KIAFEGTFEAQQLH-DTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMA 481
F + Q+ H D N+ VA TTPAN++H+LRRQ FRKP V+F K LLRHP+A
Sbjct: 794 ---FPSEEKIQREHQDCNFQVAYPTTPANLFHILRRQQHRQFRKPLVLFFSKQLLRHPLA 850
Query: 480 RSPVEDFQSGSNFQRVIP--ETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVA 307
RS + +F G FQ +I E G + + KR+V TG+VY + R+ +G + A
Sbjct: 851 RSSLSEFTDG-GFQWIIEDIEHGKAIVSKEETKRLVILTGQVYTALHKKREALG-DRTTA 908
Query: 306 LVRVEQLSPFPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLL----SIDG 142
+R+EQL PFPY ++ Y E I+W QEE NMG+W++VQPRI + L G
Sbjct: 909 FLRIEQLHPFPYAQLRDALNSYPNLEDIVWCQEEPFNMGSWAYVQPRIQTTLKETDKYSG 968
Query: 141 RATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFG 37
A +YAGR PS + A G+K H E++ + VFG
Sbjct: 969 FAFRYAGRNPSGAVAAGSKALHTTEEEAFLKDVFG 1003
>gi|6322066|ref|NP_012141.1| alpha-ketoglutarate dehydrogenase; Kgd1p
[Saccharomyces cerevisiae]
gi|730221|sp|P20967|ODO1_YEAST 2-oxoglutarate dehydrogenase E1
component, mitochondrial precursor (Alpha-ketoglutarate
dehydrogenase)
gi|1070439|pir||DEBY oxoglutarate dehydrogenase (lipoamide) (EC
1.2.4.2) precursor - yeast (Saccharomyces cerevisiae)
gi|599992|emb|CAA86867.1| 2-oxoglutarate dehydrogenase E1 component
[Saccharomyces cerevisiae]
Length = 1014
Score = 824 bits (2128), Expect = 0.0
Identities = 444/997 (44%), Positives = 635/997 (63%), Gaps = 30/997 (3%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
FL+ S++ YI++MY+AW +DPSSVH SWDAYF+N+ A
Sbjct: 44 FLSTSNATYIDEMYQAWQKDPSSVHVSWDAYFKNMSNPKIPATK-----------AFQAP 92
Query: 2760 PAAAQVT--TSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGIN-SAD 2590
P+ + T +AP T + +++S HLK+QLL R+YQ RGH A +DPLGI+ ++
Sbjct: 93 PSISNFPQGTEAAPLGTAMTGSVDENVSIHLKVQLLCRAYQVRGHLKAHIDPLGISFGSN 152
Query: 2589 LDDTIPPELELSFYGLGERDLDREFLLPP---TTFISEKKS-LTLREILQRLKDIYCTST 2422
++ +PPEL L +YG + DLD+E L P F + KS ++L+EI+ L+ +YC+S
Sbjct: 153 KNNPVPPELTLDYYGFSKHDLDKEINLGPGILPRFARDGKSKMSLKEIVDHLEKLYCSSY 212
Query: 2421 GVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRF 2242
GV+Y H+ + ++ DW+R R E P + + DQK+ + RL +T FE FL+ K+P++KRF
Sbjct: 213 GVQYTHIPSKQKCDWLRERIEIPEPYQYTVDQKRQILDRLTWATSFESFLSTKFPNDKRF 272
Query: 2241 GLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEP 2062
GLEG E ++P +K ++D S LGV+ V+GM HRGRLNVL+NV R+P +I S+F
Sbjct: 273 GLEGLESVVPGIKTLVDRSVELGVEDIVLGMAHRGRLNVLSNVVRKPNESIFSEFKGSSA 332
Query: 2061 AD--EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGD 1888
D EGSGDVKYHLG+ +R S K V +++VANPSHLE+ DPVV+G+ RA D
Sbjct: 333 RDDIEGSGDVKYHLGMNYQRPTT-SGKYVNLSLVANPSHLESQDPVVLGRTRALLHAKND 391
Query: 1887 EK-CDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSR 1711
K + + +LLHGDAAFAGQGVV ET LP Y+T G IH++ NNQIGFTTDPR +R
Sbjct: 392 LKEKTKALGVLLHGDAAFAGQGVVYETMGFLTLPEYSTGGTIHVITNNQIGFTTDPRFAR 451
Query: 1710 SSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNEL 1531
S+PY +D+ + + PIFHVN +D EAV + N+AA+WR F D I+D+V +R+HGHNE
Sbjct: 452 STPYPSDLAKAIDAPIFHVNANDVEAVTFIFNLAAEWRHKFHTDAIIDVVGWRKHGHNET 511
Query: 1530 DEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKV 1351
D+P FTQPLMY++I + K+ ++ Y EK+++EG +++ + E ++ EDA+E A+
Sbjct: 512 DQPSFTQPLMYKKIAKQKSVIDVYTEKLISEGTFSKKDIDEHKKWVWNLFEDAFEKAK-- 569
Query: 1350 TYV-RNRDWLDSPWDDFFKKR---------DPLKLPSTGXXXXXXXXXIGK-FSQYPEGF 1204
YV R+WL + W+ F + +P +P + +GK S +PEGF
Sbjct: 570 DYVPSQREWLTAAWEGFKSPKELATEILPHEPTNVPES------TLKELGKVLSSWPEGF 623
Query: 1203 NLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHH 1027
+H+ L+R LK R + ++ +DWA GEALAFG+L+ +G +VR+SG+DV+RGTFS RH
Sbjct: 624 EVHKNLKRILKNRGKSIETGEGIDWATGEALAFGTLVLDGQNVRVSGEDVERGTFSQRHA 683
Query: 1026 VLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFG 847
VLHDQ+ + IY PL+ L+ + ++T+ NSSLSEY V+GFE GYS+ P+ LV+WEAQFG
Sbjct: 684 VLHDQQ-SEAIYTPLSTLNNEKADFTIANSSLSEYGVMGFEYGYSLTSPDYLVMWEAQFG 742
Query: 846 DFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI 667
DF+NTAQ IIDQFI+ G+ KW ++SGLV+ LPHGY+G GPEHSS R ERFLQ+ NED
Sbjct: 743 DFANTAQVIIDQFIAGGEQKWKQRSGLVLSLPHGYDGQGPEHSSGRLERFLQLANEDPRY 802
Query: 666 DLEKIAFEGTFEAQQLH-DTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRH 490
F + Q+ H D N+ V TTPAN++H+LRRQ FRKP +F K LLRH
Sbjct: 803 ------FPSEEKLQRQHQDCNFQVVYPTTPANLFHILRRQQHRQFRKPLALFFSKQLLRH 856
Query: 489 PMARSPVEDFQSGSNFQRVIP--ETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKEN 316
P+ARS + +F G FQ +I E G + KR+V +G+VY + R+ +G +
Sbjct: 857 PLARSSLSEFTEG-GFQWIIEDIEHGKSIGTKEETKRLVLLSGQVYTALHKRRESLG-DK 914
Query: 315 DVALVRVEQLSPFPYDLVQQECRKYQG-AEILWAQEEHKNMGAWSFVQPRINSLLSIDGR 139
A +++EQL PFP+ ++ Y EI+W QEE NMG+W++ +PR+++ L +
Sbjct: 915 TTAFLKIEQLHPFPFAQLRDSLNSYPNLEEIVWCQEEPLNMGSWAYTEPRLHTTLKETDK 974
Query: 138 ----ATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVF 40
+Y GR PS + A G+K H+ E+ + VF
Sbjct: 975 YKDFKVRYCGRNPSGAVAAGSKSLHLAEEDAFLKDVF 1011
>gi|171785|gb|AAA34721.1| alpha-ketoglutarate dehydrogenase
Length = 1014
Score = 816 bits (2108), Expect = 0.0
Identities = 441/997 (44%), Positives = 630/997 (62%), Gaps = 30/997 (3%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
FL+ S++ YI++MY+AW +DPSSVH SWDAYF+N+ A
Sbjct: 44 FLSTSNATYIDEMYQAWQKDPSSVHVSWDAYFKNMSNPKIPATK-----------AFQAP 92
Query: 2760 PAAAQVT--TSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGIN-SAD 2590
P+ + T +AP T + +++S HLK+QLL R+YQ RGH A +DPLGI+ ++
Sbjct: 93 PSISNFPQGTEAAPLGTAMTGSVDENVSIHLKVQLLCRAYQVRGHLKAHIDPLGISFGSN 152
Query: 2589 LDDTIPPELELSFYGLGERDLDREFLLPP---TTFISEKKS-LTLREILQRLKDIYCTST 2422
++ +PPEL L +YG + DLD+E L P F + KS ++L+EI+ L+ +YC+S
Sbjct: 153 KNNPVPPELTLDYYGFSKHDLDKEINLGPGILPRFARDGKSKMSLKEIVDHLEKLYCSSY 212
Query: 2421 GVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRF 2242
GV+Y H+ + ++ DW+R R E P + + DQK+ + RL +T FE FL+ K+P++KRF
Sbjct: 213 GVQYTHIPSKQKCDWLRERIEIPEPYQYTVDQKRQILDRLTWATSFESFLSTKFPNDKRF 272
Query: 2241 GLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEP 2062
GLEG E ++P +K ++D S LGV+ V+GM HRGRLNVL+NV R+P +I
Sbjct: 273 GLEGLESVVPGIKTLVDRSVELGVEDIVLGMAHRGRLNVLSNVVRKPNESIFLNLKGSSA 332
Query: 2061 AD--EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGD 1888
D EGSGDVKYHLG+ +R S K V +++VANPSHLE+ DPVV+G+ RA D
Sbjct: 333 RDDIEGSGDVKYHLGMNYQRPTT-SGKYVNLSLVANPSHLESQDPVVLGRTRALLHAKND 391
Query: 1887 EK-CDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSR 1711
K + + +LLHGDAAFAGQGVV ET LP Y+T G IH++ NNQIGFTTDPR +R
Sbjct: 392 LKEKTKALGVLLHGDAAFAGQGVVYETMGFLTLPEYSTGGTIHVITNNQIGFTTDPRFAR 451
Query: 1710 SSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNEL 1531
S+PY +D+ + + PIFHVN +D EAV + N+AA+WR F D I+D+V +R+HGHNE
Sbjct: 452 STPYPSDLAKAIDAPIFHVNANDVEAVTFIFNLAAEWRHKFHTDAIIDVVGWRKHGHNET 511
Query: 1530 DEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKV 1351
D P FTQPLMY++I + K+ ++ Y EK+++EG +++ + E ++ EDA+E +
Sbjct: 512 DRPSFTQPLMYKKIAKQKSVIDVYTEKLISEGTFSKKDIDEHKKWVWNLFEDAFEKTK-- 569
Query: 1350 TYV-RNRDWLDSPWDDFFKKR---------DPLKLPSTGXXXXXXXXXIGK-FSQYPEGF 1204
YV R+WL + W+ F + +P +P + +GK S +PEGF
Sbjct: 570 DYVPSQREWLTAAWEGFKSPKELATEILPHEPTNVPES------TLKELGKVLSSWPEGF 623
Query: 1203 NLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHH 1027
+H+ L+R LK R + ++ +DWA GEALAFG+L+ +G +VR+SG+DV+RGTFS RH
Sbjct: 624 EVHKNLKRILKNRGKSIETGEGIDWATGEALAFGTLVLDGQNVRVSGEDVERGTFSQRHA 683
Query: 1026 VLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFG 847
VLHDQ+ + IY PL+ L+ + ++T+ NSSLSEY V+GFE GYS+ P+ LV+WEAQFG
Sbjct: 684 VLHDQQ-SEAIYTPLSTLNNEKADFTIANSSLSEYGVMGFEYGYSLTSPDYLVMWEAQFG 742
Query: 846 DFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI 667
DF+NTAQ IIDQFI+ G+ KW ++SGLV+ LPHGY+G GPEHSS R ERFLQ+ NED
Sbjct: 743 DFANTAQVIIDQFIAGGEQKWKQRSGLVLSLPHGYDGQGPEHSSGRLERFLQLANEDPRY 802
Query: 666 DLEKIAFEGTFEAQQLH-DTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRH 490
F + Q+ H D N+ V TTPAN++H+LRRQ FRKP +F K LLRH
Sbjct: 803 ------FPSEEKLQRQHQDCNFQVVYPTTPANLFHILRRQQHRQFRKPLALFFSKQLLRH 856
Query: 489 PMARSPVEDFQSGSNFQRVIP--ETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKEN 316
P+ARS + +F G FQ +I E G + KR+V +G+VY + R+ +G +
Sbjct: 857 PLARSSLSEFTEG-GFQWIIEDIEHGKSIGTKEETKRLVLLSGQVYTALHKRRESLG-DK 914
Query: 315 DVALVRVEQLSPFPYDLVQQECRKYQG-AEILWAQEEHKNMGAWSFVQPRINSLLSIDGR 139
A +++EQL PFP+ ++ Y EI+W QEE NMG+W++ +PR+++ L +
Sbjct: 915 TTAFLKIEQLHPFPFAQLRDSLNSYPNLEEIVWCQEEPLNMGSWAYTEPRLHTTLKETDK 974
Query: 138 ----ATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVF 40
+Y GR PS + A G+K H+ E+ + VF
Sbjct: 975 YKDFKVRYCGRNPSGAVAAGSKSLHLAEEDAFLKDVF 1011
>gi|7431583|pir||T05894 probable oxoglutarate dehydrogenase
(lipoamide) (EC 1.2.4.2) - Arabidopsis thaliana
gi|2827711|emb|CAA16684.1| oxoglutarate dehydrogenase - like protein
[Arabidopsis thaliana]
Length = 973
Score = 808 bits (2087), Expect = 0.0
Identities = 452/1018 (44%), Positives = 609/1018 (59%), Gaps = 34/1018 (3%)
Frame = -1
Query: 2997 STLVQHRNQSVAAAVKHEP-------FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRN 2839
ST+++ + +S A + P FL+G+SS+Y+E++ AW DP+SV SWD +FRN
Sbjct: 43 STILKSKAESAAPVPRPVPLSKLTDSFLDGTSSVYLEELQRAWEADPNSVDESWDNFFRN 102
Query: 2838 VEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLL 2659
+ G SP S Q+I + +++ LL
Sbjct: 103 ------------------FVGQASTSP-----------------GISGQTIQESMRLLLL 127
Query: 2658 IRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLL---PPTTFIS 2488
+R+YQ GH A LDPLG+ + IP +L YG E DLDREF L + F+S
Sbjct: 128 VRAYQVNGHMKAKLDPLGLEKRE----IPEDLTPGLYGFTEADLDREFFLGVWRMSGFLS 183
Query: 2487 EKKSL-TLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLF 2311
E + + TLR IL RL+ YC + G EYMH+ + ++ +W+R + E P + + +++ V++
Sbjct: 184 ENRPVQTLRSILSRLEQAYCGTIGYEYMHIADRDKCNWLRDKIETPTPRQYNSERRMVIY 243
Query: 2310 KRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRL 2131
RL ST+FE FLA KW + KRFGLEG E LIP MK++ D S+ LGV++ VIGMPHRGRL
Sbjct: 244 DRLTWSTQFENFLATKWTTAKRFGLEGAESLIPGMKEMFDRSADLGVENIVIGMPHRGRL 303
Query: 2130 NVLANVCRQPLATILSQFS-TLEPADE-----GSGDVKYHLGVCIERLNRQSQKNVKIAV 1969
NVL NV R+PL I S+FS P DE G+GDVKYHLG +R R K++ +++
Sbjct: 304 NVLGNVVRKPLRQIFSEFSGGTRPVDEVGLYTGTGDVKYHLGTSYDRPTR-GGKHLHLSL 362
Query: 1968 VANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLP 1789
VANPSHLEAVDPVV+GK RA+ +Y DE + M IL+HGD +FAGQGVV ET +L LP
Sbjct: 363 VANPSHLEAVDPVVIGKTRAKQYYTKDENRTKNMGILIHGDGSFAGQGVVYETLHLSALP 422
Query: 1788 SYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVA 1609
+Y T G +HIVVNNQ+ FTTDPR RSS YCTDV + + PIFHVN DD EAV+H C +A
Sbjct: 423 NYCTGGTVHIVVNNQVAFTTDPREGRSSQYCTDVAKALSAPIFHVNADDIEAVVHACELA 482
Query: 1608 ADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVA 1429
A+WR+TF DV+VDLVCYRR GHNE+DEP FTQP MY+ I+ ++L+ YQEK+L G
Sbjct: 483 AEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIRSHPSSLQIYQEKLLQSGQV 542
Query: 1428 NEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXX 1249
++ + + K SIL + YE A K + RDWL S W F ++ +TG
Sbjct: 543 TQEDIDKIQKKVSSILNEEYE-ASKDYIPQKRDWLASHWTGFKSPEQISRIRNTGVKPEI 601
Query: 1248 XXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKD-NSLDWACGEALAFGSLLKEGIHVRL 1072
S +PE F HRG++R + R QM++ +DW GEALAF +L+ EG HVRL
Sbjct: 602 LKNVGKAISTFPENFKPHRGVKRVYEQRAQMIESGEGIDWGLGEALAFATLVVEGNHVRL 661
Query: 1071 SGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGE--YTVCNSSLSEYAVLGFELG 898
SGQDV+RGTFSHRH VLHDQ+ ++ Y PL+ L + Q +TV NSSLSE+ VLGFELG
Sbjct: 662 SGQDVERGTFSHRHSVLHDQETGEE-YCPLDHLIKNQDPEMFTVSNSSLSEFGVLGFELG 720
Query: 897 YSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHS 718
YSM +PNSLVIWEAQFGDF+N AQ + DQFISSG++KW+RQ+GLV+LLPHGY+G GPEHS
Sbjct: 721 YSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHS 780
Query: 717 SARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMP 538
S R ERFLQM +++ + E + T +Q+ + NW V N TTPAN +H+LRRQ+
Sbjct: 781 SGRLERFLQMSDDNPYVIPE---MDPTLR-KQIQECNWQVVNVTTPANYFHVLRRQIHRD 836
Query: 537 FRKPAVVFSPKSLLRHPMARSPVEDF----------QSGSNFQRVIPETGAPSQNPPDVK 388
FRKP +V +PK+LLRH S + +F + G+ F+R+I + S D +
Sbjct: 837 FRKPLIVMAPKNLLRHKQCVSNLSEFDDVKGHPGFDKQGTRFKRLIKDQSGHSDLEEDAE 896
Query: 387 RVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEE 208
+V+C QEE
Sbjct: 897 -IVWC----------------------------------------------------QEE 903
Query: 207 HKNMGAWSFVQPRINSLLSIDGRAT----KYAGRLPSSSPATGNKFTHMQEQKEMMSK 46
NMG + ++ R+ + + R KY GRLPS++ ATG H++EQ +++ K
Sbjct: 904 PMNMGGYQYIALRLCTAMKALQRGNFNDIKYVGRLPSAATATGFYQLHVKEQTDLVKK 961
>gi|50554651|ref|XP_504734.1| hypothetical protein [Yarrowia
lipolytica]
gi|49650603|emb|CAG80338.1| unnamed protein product [Yarrowia
lipolytica CLIB99]
Length = 894
Score = 802 bits (2071), Expect = 0.0
Identities = 437/906 (48%), Positives = 590/906 (64%), Gaps = 27/906 (2%)
Frame = -1
Query: 2676 LKIQLLIRSYQTRGHNIADLDPLGIN-SADLDDTIPPELELSFYGLGERDLDREFLLPP- 2503
+K QLL+R+YQ RGH A +DPLGI+ +D + P EL L FYG ++DLD E L P
Sbjct: 1 MKAQLLVRAYQVRGHTKAKIDPLGISFGSDKNKKPPKELTLEFYGWTDKDLDTEITLGPG 60
Query: 2502 --TTFISE-KKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSH 2332
F+ K TLREI+ + IYC S GVEY+H+ + E+ +WIR R E P+ +
Sbjct: 61 ILPRFVENGKNKRTLREIIMDCERIYCGSYGVEYIHIPSREECEWIRDRVETPKPYNYTP 120
Query: 2331 DQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIG 2152
DQK+ + RLI + FE FLA K+P++KRFGLEG E ++ MK +ID S G++ VIG
Sbjct: 121 DQKRRMLDRLIWANLFETFLASKFPNDKRFGLEGAETVVVGMKTLIDRSVDAGIEDIVIG 180
Query: 2151 MPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIA 1972
MPHRGRLN+L+NV R+P +I ++F DEGSGDVKYHLG +R S K V ++
Sbjct: 181 MPHRGRLNMLSNVVRKPNESIFAEFQGSAVFDEGSGDVKYHLGANYQRPT-PSGKKVNLS 239
Query: 1971 VVANPSHLEAVDPVVMGKVRAEAFYAGDEKC-DRTMAILLHGDAAFAGQGVVLETFNLDD 1795
+VANPSHLEA DPVV+GK RA D D+ M +L+HGDAAFAGQGVV ET +
Sbjct: 240 LVANPSHLEAEDPVVLGKTRAIQHMKHDVGTFDKAMGVLMHGDAAFAGQGVVYETMGMHS 299
Query: 1794 LPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCN 1615
LP+Y+T G IHI+VNNQIGFTTDPR SRS+PY +D+ + + PIFHVN DD EAV + N
Sbjct: 300 LPAYSTGGTIHIIVNNQIGFTTDPRFSRSTPYPSDLAKSIDAPIFHVNADDMEAVDFIFN 359
Query: 1614 VAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEG 1435
+AADWR TFK DVI+DLVCYR+ GHNE D+P FTQPLMY++I L+ Y +K+L E
Sbjct: 360 LAADWRATFKSDVIIDLVCYRKFGHNETDQPSFTQPLMYKKIADKPNPLDIYVDKLLKEK 419
Query: 1434 VANEQYVKEELTKYGSILEDAYENAQKVTYV-RNRDWLDSPWDDFFKKRDPLKLPS---- 1270
++ ++E +LE++++ ++ YV ++WL SPWDDF + P +L +
Sbjct: 420 TFTKEDIEEHKQWVWGMLEESFKKSK--DYVPHQKEWLASPWDDF---KTPKELATEILP 474
Query: 1269 ---TGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKD-NSLDWACGEALAFGS 1102
T S PEGF LHR L+R L R + +++ + +DW+ GEALAFG+
Sbjct: 475 HLPTSVEEKKLKEIGKVISSVPEGFTLHRNLKRILSNRGKSVEEGHGIDWSTGEALAFGT 534
Query: 1101 LLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEY 922
LL+EG HVRLSGQDV+RGTFS RH V+HDQ V++ Y PLN L++ Q ++TV NS LSEY
Sbjct: 535 LLEEGHHVRLSGQDVERGTFSQRHAVVHDQ-VNETTYVPLNHLTKDQADFTVSNSHLSEY 593
Query: 921 AVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGY 742
V+GFE GYS+ P +LVIWEAQFGDF+NTAQ IIDQFI+S ++KW ++SGLV+ LPHGY
Sbjct: 594 GVMGFEYGYSLASPEALVIWEAQFGDFANTAQVIIDQFIASAETKWSQRSGLVLSLPHGY 653
Query: 741 EGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLH-DTNWIVANCTTPANIYH 565
+G GPEHSS R ER+L + NED + F + ++ H D N +A TTPANI+H
Sbjct: 654 DGQGPEHSSGRIERYLLLGNED------PLHFPSPDKLERQHQDCNIQIAYPTTPANIFH 707
Query: 564 LLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPET--GAPSQNPPDV 391
L RRQ+ FRKP F K+LLR+PMA+S + +F S+FQ VI + G N +
Sbjct: 708 LYRRQMHRAFRKPLACFFSKNLLRNPMAKSDLSEFVGESHFQWVIEDDQHGKTINNKEGI 767
Query: 390 KRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQG-AEILWAQ 214
+RV+FC+G+V+ + R+ + + A++R+EQL PFP++ V++ Y +I WAQ
Sbjct: 768 ERVLFCSGQVWTALFKRREDLA-DKKTAIIRIEQLHPFPWEQVRELLDSYPNLKDICWAQ 826
Query: 213 EEHKNMGAWSFVQPRINSLLSIDGRATK--------YAGRLPSSSPATGNKFTHMQEQKE 58
EE N GAW +QPR+ + +ATK YAGR PS+S A G K H+ E++
Sbjct: 827 EEPLNAGAWVHIQPRMYTTF----QATKNHKHAHIRYAGRKPSASVAAGTKKLHLAEEEA 882
Query: 57 MMSKVF 40
++ + F
Sbjct: 883 LLKQAF 888
>gi|23014366|ref|ZP_00054186.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Magnetospirillum magnetotacticum]
Length = 989
Score = 785 bits (2027), Expect = 0.0
Identities = 440/991 (44%), Positives = 599/991 (60%), Gaps = 27/991 (2%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXA-----YAG 2776
FL+G ++++I ++Y +L+DPSSV +SW A+F++++ A G
Sbjct: 10 FLSGGNAVFIAELYARYLEDPSSVDSSWVAFFQDLKDDGSQLISDFKGTANARRDIQIIG 69
Query: 2775 ALGVSPAAAQVTTS-----------SAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHN 2629
A+ AAA + +APA D A Q+ D ++ +LIRSY+ RGH
Sbjct: 70 AIDPEAAAAAAAAAKKGGKDSAPKGAAPAAA-DPAAIRQAQVDSIRALMLIRSYRVRGHL 128
Query: 2628 IADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQR 2449
+A LDPL + + PEL+ YG + DLDRE + + K LR+I++
Sbjct: 129 MAKLDPLELTKPEQH----PELDYRTYGFTDADLDREIFIDHVLGLESAK---LRDIVRI 181
Query: 2448 LKDIYCTSTGVEYMHLNNLEQQDWIRRRFEA-PRVTELSHDQKKVLFKRLIRSTKFEEFL 2272
+++ YC GVE+MH+ + +Q+ WI++R E+ T+ + K + +RL + FE FL
Sbjct: 182 VQETYCAKIGVEFMHIQDPDQKAWIQKRIESIHNRTDFTPRGKTAILERLTEAEGFERFL 241
Query: 2271 AKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLAT 2092
K+ KRFGLEG E +IPA++Q++ S LGVD V+GM HRGRLNVLAN ++P
Sbjct: 242 QMKYTGTKRFGLEGGESVIPALEQILKRGSQLGVDEVVLGMAHRGRLNVLANFMKKPYQA 301
Query: 2091 ILSQF--STLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMG 1921
I S+F + P D +GSGDVKYHLG +R K V ++++ NPSHLE V P+V+G
Sbjct: 302 IFSEFQGNAASPEDVQGSGDVKYHLGTSADR--DFDGKTVHLSLMPNPSHLEVVGPLVVG 359
Query: 1920 KVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQI 1741
KVRA+ GD + R M I+LHGDAAFAGQGVV E L L Y T G +HI++NNQI
Sbjct: 360 KVRAKQTQFGDTERKRVMGIILHGDAAFAGQGVVPEVMLLSQLKGYATGGTVHIIINNQI 419
Query: 1740 GFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLV 1561
GFTT P+ SRS PY +DV + P+FHVN DDPEAV+HV +A ++R+ F DV++D+V
Sbjct: 420 GFTTAPQYSRSGPYSSDVAKGFQAPVFHVNGDDPEAVVHVARIATEYRQEFGADVVIDMV 479
Query: 1560 CYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSIL 1381
CYRRHGHNE DEP FTQPLMY++I T Y EK++ EG + + L
Sbjct: 480 CYRRHGHNESDEPAFTQPLMYRKIASHPTTRALYSEKLVAEGTITRYEADAIFANFQARL 539
Query: 1380 EDAYENAQKVTYVRNRDWLDSPWDDFFK--KRDPLKLPSTGXXXXXXXXXIGKFSQYPEG 1207
E YE A K V DWL+ W + + + + TG ++ PEG
Sbjct: 540 EGDYE-AAKSFKVNKADWLEGKWQGLVQLAEEEEFREEKTGVAADILKEVGHALARTPEG 598
Query: 1206 FNLHRGLERTLKGRQQML-KDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRH 1030
FN++R + R L +++M+ +DWA EALAFG+LL EG VRLSGQD RGTFS RH
Sbjct: 599 FNVNRKVVRQLAAKKEMVDTGEGIDWATAEALAFGTLLIEGNGVRLSGQDCGRGTFSQRH 658
Query: 1029 HVLHDQKVDQKIYNPLNDLSEG-QGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQ 853
L DQ+ +++I PLN + G Q + V +S LSE AVLGFE GYS +PN+L +WE Q
Sbjct: 659 CRLTDQETEERI-EPLNAIRPGKQAYFEVMDSPLSEEAVLGFEYGYSQAEPNTLTLWEGQ 717
Query: 852 FGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDD 673
FGDF+N AQ IIDQFI+SG+SKW+R SGLVMLLPHGYEG GPEHSSAR ER+LQ+ ED
Sbjct: 718 FGDFANGAQVIIDQFINSGESKWLRMSGLVMLLPHGYEGQGPEHSSARWERYLQLSGED- 776
Query: 672 EIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLR 493
NW V N TTPAN +H LRRQ+ FRKP ++ +PKSLLR
Sbjct: 777 ---------------------NWQVCNITTPANYFHALRRQLRRNFRKPLIIMTPKSLLR 815
Query: 492 HPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKEND 313
H + S +++ SGS F+RV+PET + + ++RV+ C+GKVYYD++ R G + D
Sbjct: 816 HKLCVSKLDELISGSRFRRVLPETEKLAAD-SKIRRVLLCSGKVYYDLLEERTKRGLK-D 873
Query: 312 VALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSL---LSIDG 142
VA++RVEQL P+P D ++ + +Y AE+LW QEE NMG W+FV RI + L I
Sbjct: 874 VAIIRVEQLYPWPKDTIKAQLARYPNAELLWVQEEPANMGPWTFVDRRIEFICEELDIKA 933
Query: 141 RATKYAGRLPSSSPATGNKFTHMQEQKEMMS 49
R Y GR ++SPATG TH+ EQ+ + S
Sbjct: 934 RKALYCGRRAAASPATGLYKTHVAEQEWITS 964
>gi|46192007|ref|ZP_00007567.2| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Rhodobacter sphaeroides]
Length = 987
Score = 783 bits (2022), Expect = 0.0
Identities = 436/1011 (43%), Positives = 601/1011 (59%), Gaps = 36/1011 (3%)
Frame = -1
Query: 2973 QSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXX 2794
QS A FL G ++ YI+Q+ + +DP+SV W FR++
Sbjct: 4 QSPNAQFHASSFLQGQNAEYIDQLQARYAEDPASVDAGWAELFRSLGDSELDAKRQAHGP 63
Query: 2793 XXA-----------YAGALGVSPAAAQVTTSSAPATRLDTNASVQSIS-----------D 2680
+ AL AA + A ++ A+ Q +S D
Sbjct: 64 SWSRPDWPPMPADDLTAALTGEWPAAPAKEAKAAGQKIQAKAAEQGVSLSDAQVQRAVLD 123
Query: 2679 HLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPT 2500
++ ++IR+Y+ RGH ADLDPLG+ + T PEL+ YG + D+DR +
Sbjct: 124 SIRALMIIRAYRIRGHLAADLDPLGLRNT----TNHPELDPKSYGFTDADMDRPIFIDNV 179
Query: 2499 TFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEA-PRVTELSHDQK 2323
+ + ++R+I+ +K YC + ++YMH+++ EQ W++ R E + + + +
Sbjct: 180 LGL---QVASMRQIVDIVKRTYCGTFALQYMHISDPEQAAWLKERIEGYGKEIHFTREGR 236
Query: 2322 KVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPH 2143
+ + +L+ + FE+FL K+ KRFGL+G E LIPAM+Q+I LGV V+GMPH
Sbjct: 237 RAILNKLVEAEGFEKFLHVKYMGTKRFGLDGGEALIPAMEQIIKRGGALGVKEIVVGMPH 296
Query: 2142 RGRLNVLANVCRQPLATILSQFS--TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIA 1972
RGRL+VLANV +P I ++F + +P + +GSGDVKYHLG +R V ++
Sbjct: 297 RGRLSVLANVMAKPYRAIFNEFQGGSFKPEEVDGSGDVKYHLGASSDR--DFDGNTVHLS 354
Query: 1971 VVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDL 1792
+ ANPSHLEAV+PVV+GKVRA+ AGD+ + ILLHGDAAFAGQGVV E F L L
Sbjct: 355 LTANPSHLEAVNPVVLGKVRAKQEQAGDKTRHTVLPILLHGDAAFAGQGVVAECFGLSGL 414
Query: 1791 PSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNV 1612
+ T G IHIVVNNQIGFTT P SRSSPY TD+ +V PIFHVN DDPEAV+H V
Sbjct: 415 VGHRTGGTIHIVVNNQIGFTTAPSFSRSSPYPTDIALMVEAPIFHVNGDDPEAVVHAAKV 474
Query: 1611 AADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGV 1432
A ++R+ F KDV++D+ CYRR GHNE DEPMFT P MY IK+ KT L+ Y E+++ +G+
Sbjct: 475 ATEFRQKFHKDVVIDIFCYRRFGHNEGDEPMFTNPSMYTSIKKHKTTLQLYTERLVRDGL 534
Query: 1431 ANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXX 1252
E +++ + + L + +E A K DWLD W + D + T
Sbjct: 535 IPEGEIEDMKAAFQAKLNEEFE-AGKDFKPNKADWLDGRWKHIDRHGDEYQPGRTSISAE 593
Query: 1251 XXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVR 1075
++ PEGF+LH+ + R L+ ++QM + DWA GEALAFGS + EG VR
Sbjct: 594 TLQEIGQALTRVPEGFDLHKTVGRQLEAKKQMFETGRGFDWATGEALAFGSFVVEGYPVR 653
Query: 1074 LSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGY 895
LSGQD RGTFS RH +Q +++ Y PLN++ GQ Y V +S LSEYAVLGFE GY
Sbjct: 654 LSGQDCTRGTFSQRHSAFINQSTEERYY-PLNNIRSGQARYEVIDSMLSEYAVLGFEYGY 712
Query: 894 SMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSS 715
S+ +PN+LV+WEAQFGDF+N AQ + DQFI+SG+SKW+R SGLV+LLPHG+EG GPEHSS
Sbjct: 713 SLAEPNALVMWEAQFGDFANGAQIMFDQFINSGESKWLRMSGLVVLLPHGFEGQGPEHSS 772
Query: 714 ARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPF 535
AR ERFLQM D NWIVANC+TPAN +H+LRRQ+ F
Sbjct: 773 ARLERFLQMSAND----------------------NWIVANCSTPANYFHILRRQIHRNF 810
Query: 534 RKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQN----PPD--VKRVVFC 373
RKP ++ +PKSLLRHP+ S EDF +GS F RV+ + + PD ++RVV C
Sbjct: 811 RKPLILMTPKSLLRHPLCISNAEDFTTGSGFHRVLWDDAQKGHSETVLKPDEQIRRVVMC 870
Query: 372 TGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMG 193
+GKVYYD++A R G + DV L+R+EQ PFP + +E +++ A+I+W QEE KN G
Sbjct: 871 SGKVYYDLLAERDKRGID-DVYLMRLEQFYPFPALSLVKELGRFKNAQIVWCQEEPKNQG 929
Query: 192 AWSFVQPRINSLLSIDGRA---TKYAGRLPSSSPATGNKFTHMQEQKEMMS 49
W+FV+P + +L+ G + YAGR S+SPATG H EQ +++
Sbjct: 930 GWTFVEPNLEWVLTRIGASHTRAIYAGRSASASPATGLASRHKAEQDALVN 980
>gi|48831909|ref|ZP_00288957.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Magnetococcus sp. MC-1]
Length = 981
Score = 781 bits (2016), Expect = 0.0
Identities = 438/998 (43%), Positives = 608/998 (60%), Gaps = 22/998 (2%)
Frame = -1
Query: 2946 EPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNV---EXXXXXXXXXXXXXXXAYAG 2776
+ LNG++++YI ++Y +L +P +V +W F + E +G
Sbjct: 6 DALLNGTNALYISELYARYLDNPHAVDATWATTFGELTEDETPEIFKEIRGASWSKLESG 65
Query: 2775 ALGVSPAAAQVTTSSAPATRLDTNASV---------QSISDHLKIQLLIRSYQTRGHNIA 2623
LG P + + A + V ++ D ++ ++IR+Y+ RGH IA
Sbjct: 66 ILG-KPLERDPDSQTRHAHFVQGVTQVAGTEPEQIRRATLDAIRALMMIRTYRVRGHLIA 124
Query: 2622 DLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLK 2443
+ DPLG+ + + PEL+ + YG E D+DR + ++ ++ TLR+I++ LK
Sbjct: 125 NFDPLGLEAREHH----PELDPANYGFAEEDMDRPIFID---YVLGLETATLRQIVRLLK 177
Query: 2442 DIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRV-TELSHDQKKVLFKRLIRSTKFEEFLAK 2266
+ YC + GVE+MH+ E++ W++RR E+ R T + K+ + +RL S FE FL
Sbjct: 178 ETYCGTIGVEFMHIQEPEEKAWVQRRIESIRNRTHFTLKGKRTILQRLSESEGFETFLQL 237
Query: 2265 KWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATIL 2086
K+ KRFGL+G E LIPA++Q++ + LG+ VIGM HRGRLNVLAN+ R+P A I+
Sbjct: 238 KYTGTKRFGLDGGESLIPAIEQILKRGTQLGLKEVVIGMAHRGRLNVLANIMRKPYAAIM 297
Query: 2085 SQFS--TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKV 1915
+F + +P D +GSGDV+YHLG +R+ K V +++ ANPSHLE V+PVV+GKV
Sbjct: 298 HEFQGGSNKPDDVQGSGDVRYHLGASADRVF--DDKKVHLSLTANPSHLELVNPVVLGKV 355
Query: 1914 RAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGF 1735
RA+ GD + M +++HGDAAFAGQG+V E+ L L Y T G IH++VNNQIGF
Sbjct: 356 RAKQLQRGDTSQQQVMGLIMHGDAAFAGQGLVPESLALSGLKGYQTGGTIHLIVNNQIGF 415
Query: 1734 TTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCY 1555
TT+PR+SRSSPY +DV +++ PIFHVN DDPEAV+H +A ++R+ F KDV++D+ CY
Sbjct: 416 TTNPRNSRSSPYPSDVAKMIQAPIFHVNGDDPEAVVHAARIAIEYRQAFSKDVVIDMWCY 475
Query: 1554 RRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILED 1375
RRHGHNE DEP FTQP+MY+ I T + Y +K+ EGV E ++ ++ + LE
Sbjct: 476 RRHGHNEGDEPSFTQPIMYRAIANHPTTRQVYAQKLEREGVLKEGEGEQIYKEFHNELET 535
Query: 1374 AYENAQKVTYVRNRDWLDSPWDDFFKKR--DPLKLPSTGXXXXXXXXXIGKFSQYPEGFN 1201
+++ AQ + DWLD W R + + T P+ F
Sbjct: 536 SFQEAQ-YFLPTSADWLDGMWKGVSNLRGEEEMHQHKTCVPERTLREVGKALYTPPQDFA 594
Query: 1200 LHRGLERTLKGRQQMLKD-NSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHV 1024
+HR + R L+ ++QM + DWA GEALAFG+LL EGI VRLSGQD RGTFS RH V
Sbjct: 595 VHRKIIRQLRSKEQMFESGEGFDWATGEALAFGTLLVEGIPVRLSGQDCGRGTFSQRHSV 654
Query: 1023 LHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGD 844
L DQ D+ Y PLN + Q +Y V +S L+E +VLGFE GY+ DP++LV+WEAQFGD
Sbjct: 655 LIDQN-DESRYEPLNHIRSLQADYEVIDSPLAEASVLGFEYGYASADPHALVLWEAQFGD 713
Query: 843 FSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEID 664
F N AQ IIDQFISSG+SKW+R +G+VMLLPHG+EG GPEHSSARPERFLQ+C ED
Sbjct: 714 FVNGAQMIIDQFISSGESKWLRLNGMVMLLPHGFEGQGPEHSSARPERFLQLCAED---- 769
Query: 663 LEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPM 484
N V N TTPAN +H LRRQ FRKP V+F+PKSLLRH +
Sbjct: 770 ------------------NLQVCNLTTPANYFHALRRQNHRNFRKPLVIFTPKSLLRHKL 811
Query: 483 ARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVAL 304
S +E F SGS+FQRV E + VKRVV C+GKVYY+++ R+ G NDVA+
Sbjct: 812 CVSKLEAFISGSSFQRVYDEVDTLVADEA-VKRVVLCSGKVYYELLQTRREQG-SNDVAI 869
Query: 303 VRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSL---LSIDGRAT 133
VR+EQL P+P + + + ++Y AEI+W QEE NMG WSF+ R+ L L R
Sbjct: 870 VRIEQLYPWPRNALFKVLQRYANAEIVWCQEEPANMGYWSFLFQRLIHLLEDLQSKQRLP 929
Query: 132 KYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGVPKSKL 19
YAGR S+SPA+G H+QEQ ++ + VP +++
Sbjct: 930 IYAGRGASASPASGLASKHLQEQTHLVHEALFVPLTEI 967
>gi|48764978|ref|ZP_00269529.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Rhodospirillum rubrum]
Length = 987
Score = 778 bits (2010), Expect = 0.0
Identities = 437/987 (44%), Positives = 599/987 (60%), Gaps = 28/987 (2%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVE---------------XXXXXXXXX 2806
FL G++++YI ++Y +L DPSSV SW A+F +
Sbjct: 9 FLTGANAVYIAEVYSRYLADPSSVDPSWVAFFGELRDGAEELSGDLKGPSWTSRGNAVIG 68
Query: 2805 XXXXXXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSIS-DHLKIQLLIRSYQTRGHN 2629
A G + AA +APA + A V++ + D ++ ++IR+Y+ RGH
Sbjct: 69 TADPDAPAAAKAGKNGKAAAAPVPAAPAAAGLSTAEVRAHTLDSVRALMMIRAYRVRGHL 128
Query: 2628 IADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQR 2449
+ADLDPLG+N + PEL+ YG + DL+RE + + +S TLR+I++
Sbjct: 129 VADLDPLGLNK----NNEHPELDYRSYGFTDADLEREIFIDN---VLGMESATLRKIVEV 181
Query: 2448 LKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPR-VTELSHDQKKVLFKRLIRSTKFEEFL 2272
+++ YC + GVE+MH+ + EQ+ WI+RR E R T + + K+ + +RL + FE+FL
Sbjct: 182 VRETYCGTIGVEFMHIQDPEQKSWIQRRIEGERNHTRFTPEGKRAILERLTEAEGFEKFL 241
Query: 2271 AKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLAT 2092
K+ KRFGLEG E +IPA++Q++ S LG+ +GM HRGRLN+L ++ +P
Sbjct: 242 QVKYTGTKRFGLEGGETVIPAIEQILKRGSQLGLTDINLGMAHRGRLNLLTSLLHKPYRA 301
Query: 2091 ILSQF--STLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMG 1921
I S+F ++ P D +GSGDVKYHLG +R V +++ ANPSHLEA DPVV+G
Sbjct: 302 IFSEFQGNSANPDDVQGSGDVKYHLGTSADR--EFDGAVVHLSLQANPSHLEAADPVVLG 359
Query: 1920 KVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQI 1741
KVRA+ GD MA+L+HGDAAFAGQG+V E F L L Y T G IHIV+NNQI
Sbjct: 360 KVRAKQTQLGDTDRKAVMALLIHGDAAFAGQGLVAECFGLSQLKGYRTGGTIHIVINNQI 419
Query: 1740 GFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLV 1561
GFTT P+ SRS YCTD+ ++V PIFHVN DDPEAV+H + ++R+ F DV++D+V
Sbjct: 420 GFTTSPQYSRSGQYCTDIAKMVQAPIFHVNGDDPEAVVHTARIVTEFRQEFGVDVVLDMV 479
Query: 1560 CYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSIL 1381
CYRRHGHNE DEP FTQPLMY I +T Y +K+++EG+ ++ + + L
Sbjct: 480 CYRRHGHNESDEPAFTQPLMYDSIAHRQTTRTLYAQKLVSEGLISQAEADGLADAFTARL 539
Query: 1380 EDAYENAQKVTYVRNR-DWLDSPWD--DFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPE 1210
E ++ A +Y NR DWL W+ + + + T S PE
Sbjct: 540 ETEFQAA--TSYKPNRADWLAGKWEGLEALNGEEEFRQDRTEVPAEVLRRVGTALSTPPE 597
Query: 1209 GFNLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHR 1033
F+ +R + R +K + +ML+ +DWA EALAFG+LL EG VRLSGQD RGTFSHR
Sbjct: 598 NFDTNRKILRQMKAKAEMLETGQGIDWATAEALAFGTLLLEGTRVRLSGQDSGRGTFSHR 657
Query: 1032 HHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQ 853
H VL DQ ++ + PL+ L Q + V +S LSE++VLGFE GYS+ +P +LV+WEAQ
Sbjct: 658 HSVLIDQ-TNENRHIPLDHLDPAQARFEVIDSPLSEFSVLGFEYGYSLAEPKALVLWEAQ 716
Query: 852 FGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDD 673
FGDF+N AQ I DQFISS +SKW+R SGLV LLPHGYEG GPEHSSARPER+LQ+C ED
Sbjct: 717 FGDFANGAQVIFDQFISSAESKWLRMSGLVCLLPHGYEGQGPEHSSARPERYLQLCAED- 775
Query: 672 EIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLR 493
N V N T+PAN +H LRRQV FRKP +V +PKSLLR
Sbjct: 776 ---------------------NMQVVNITSPANYFHALRRQVHRNFRKPLIVMAPKSLLR 814
Query: 492 HPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKEND 313
H +A SP+ DF + F+RV+PET ++ + RVV C+GKVYYD+ AR+ G + D
Sbjct: 815 HKLAVSPLSDF-TDHGFRRVLPETKTLVED-DKITRVVLCSGKVYYDLYQAREDQGID-D 871
Query: 312 VALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLS----ID 145
VA+VR+EQL P+P D + + ++Y A+++W QEE NMG W+FV RI L
Sbjct: 872 VAIVRIEQLYPWPKDTLMKVLKRYPNADVVWCQEEPANMGYWTFVDRRIEFFLQELEHRP 931
Query: 144 GRATKYAGRLPSSSPATGNKFTHMQEQ 64
GRA+ YAGR ++SPATG+ H +EQ
Sbjct: 932 GRAS-YAGRPAAASPATGSNRGHGREQ 957
>gi|1145803|gb|AAA86904.1| alpha-ketoglutarate dehydrogenase
gi|1814068|gb|AAC45481.1| 2-oxoglutarate dehydrogenase [Rhodobacter
capsulatus]
Length = 989
Score = 770 bits (1989), Expect = 0.0
Identities = 427/1003 (42%), Positives = 597/1003 (58%), Gaps = 40/1003 (3%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAG----- 2776
FL G+++ Y+EQ+Y + DP+SV +W ++F ++ A A
Sbjct: 15 FLQGANADYVEQLYARYAADPTSVDPNWASFFESLGDTELDAKRSAHGPSWARADWPPSP 74
Query: 2775 ------------ALGVSP----AAAQVTTSSAPAT--RLDTNASVQSISDHLKIQLLIRS 2650
+ V+P AAA+ ++ A ++ A +++ D ++ ++I +
Sbjct: 75 NDDLTAAMTGEWPMPVAPKENKAAAEKLAAAVKAAGVQVSDEAIKRAVLDSIRALMIIPT 134
Query: 2649 YQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLT 2470
Y+ RGH IADLDPLG+ S + PEL+ YG E D+DR + + + +
Sbjct: 135 YRFRGHLIADLDPLGMRSGESH----PELDPRSYGFTEADMDRMIFIDNVLGL---QVAS 187
Query: 2469 LREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEA-PRVTELSHDQKKVLFKRLIRS 2293
+R+IL LK YC + ++YMH++N E+ W++ R E + + + ++ + +L+ +
Sbjct: 188 MRQILDVLKRTYCGTFALQYMHISNPEEAAWLKERIEGYGKEIAFTREGRRAILNKLVEA 247
Query: 2292 TKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANV 2113
E+FL K+ KRFGL+G E LIPAM+Q+I LG+ VIGMPHRGRLN+L V
Sbjct: 248 DGSEKFLHVKYTGTKRFGLDGGEALIPAMEQIIKRGGALGLKEVVIGMPHRGRLNILLTV 307
Query: 2112 CRQPLATILSQFS--TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEA 1942
+P I +F + +P D +GSGDVKYHLG +R V +++ ANPSHLEA
Sbjct: 308 MEKPYRAIFHEFQGGSYKPEDVDGSGDVKYHLGASSDR--SCDGHTVHLSLTANPSHLEA 365
Query: 1941 VDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIH 1762
V+PVV+GKVRA+ A DE + +++LLHGDAAFAGQG+V E L + + T G IH
Sbjct: 366 VNPVVLGKVRAKQDQAHDEDRTQVLSVLLHGDAAFAGQGIVAECLQLSGIKGHRTGGCIH 425
Query: 1761 IVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKK 1582
IVVNNQIGFTT P SR+SPY TD+ +V PIFHVN DDPEAV+H VA ++R+ F K
Sbjct: 426 IVVNNQIGFTTAPHFSRTSPYPTDIALMVEAPIFHVNGDDPEAVVHAAKVATEFRQKFHK 485
Query: 1581 DVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEEL 1402
DV++D+ CYRR GHNE DEPMFT P MY+ IK KT L+ Y E+++ +G+ E +++
Sbjct: 486 DVVIDIFCYRRFGHNEGDEPMFTNPAMYKNIKGHKTTLQLYTERLVADGLIPEGEIEDMK 545
Query: 1401 TKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFS 1222
+ + L + YE A K DWLD W ++ T +
Sbjct: 546 AVFQAKLNEEYE-AGKTFRPNKADWLDGRWKHLDRQSSDYDAGVTPISPELMAEVGKALT 604
Query: 1221 QYPEGFNLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGT 1045
YPE F++H+ + R L+ ++ M + DWA EALAFGSLL EG VRL+GQD RGT
Sbjct: 605 SYPEDFDIHKTVARQLEAKKAMFETGKGFDWATAEALAFGSLLAEGFPVRLAGQDCTRGT 664
Query: 1044 FSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVI 865
FS RH L DQ +++ Y PLN + GQ +Y V +S LSEYAVLGFE GYS+ +PN+L +
Sbjct: 665 FSQRHSGLIDQATEERYY-PLNHIKPGQAKYEVIDSMLSEYAVLGFEYGYSLAEPNALTL 723
Query: 864 WEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMC 685
WEAQFGDF+N AQ + DQFI+SG+ KW+R SGLV LLPHG+EG GPEHSSAR ER+LQ+
Sbjct: 724 WEAQFGDFANGAQIMFDQFINSGERKWLRMSGLVCLLPHGFEGQGPEHSSARLERYLQLS 783
Query: 684 NEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPK 505
ED NWIVANC+TPAN +H+LRRQ+ FRKP ++ +PK
Sbjct: 784 AED----------------------NWIVANCSTPANYFHILRRQIHRNFRKPLILMTPK 821
Query: 504 SLLRHPMARSPVEDFQSGSNFQRVIPET-------GAPSQNPPD--VKRVVFCTGKVYYD 352
SLLRHP+ S +F +GS F+RV+ + + PD + RVV C+GKVYYD
Sbjct: 822 SLLRHPLCTSTAAEFTTGSFFRRVMWDDADAQHHGNSQMTTKPDAEISRVVMCSGKVYYD 881
Query: 351 MVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQP 172
++A R G E DV ++R+EQL PFP + E +++ A+I+W QEE KN GAWSF++P
Sbjct: 882 LLAERDKRGLE-DVYILRIEQLYPFPAHSLVTELGRFKEAQIIWCQEEPKNQGAWSFIEP 940
Query: 171 RINSLLSIDGR---ATKYAGRLPSSSPATGNKFTHMQEQKEMM 52
+ +L+ G +YAGR S+SPATG H EQ ++
Sbjct: 941 NLEWVLAKIGAKHGRARYAGRAASASPATGLASRHKAEQDALV 983
>gi|22652788|gb|AAN03815.1| 2-oxoglutarate dehydrogenase E1 component
[Methylobacterium extorquens]
Length = 996
Score = 770 bits (1988), Expect = 0.0
Identities = 441/1028 (42%), Positives = 602/1028 (57%), Gaps = 48/1028 (4%)
Frame = -1
Query: 2973 QSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYF-----------RNVEXX 2827
Q A+ FL G+++ +IE++ A+ +DP+SV W +F +N E
Sbjct: 4 QDANEALLRTSFLYGANAAWIEELQAAYARDPNSVDPEWQRFFEDLGEDDALVKKNAEGA 63
Query: 2826 XXXXXXXXXXXXXAYAGALGVSPAAAQVT----------------TSSAPATRLDTNASV 2695
AL + A + T ++ A T SV
Sbjct: 64 SWAKPNWPVVANGEIVSALDGNWGALEKTFGEKIQAKAQPGKPGDSTKGAAIVAATGVSV 123
Query: 2694 -QSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDRE 2518
Q+ D ++ +LIR+Y+ RGH A LDP+G+ + + P+ YG E D DR+
Sbjct: 124 EQATKDSVRAIMLIRAYRMRGHLHAKLDPIGLAPRGDHEELHPQ----HYGFQESDWDRK 179
Query: 2517 FLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAP-RVTE 2341
L + + T+REI+ L+ YC + GVE+MH+++ E++ WI+ R E +
Sbjct: 180 IFLDN---VLGMEFSTIREIVAILERTYCQTLGVEFMHISDPEEKAWIQERIEGKDKEIS 236
Query: 2340 LSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSF 2161
+ + ++ + +LI + FE+FL K+ KRFGL+G E ++PAM+Q+I LGV+
Sbjct: 237 FTPEGRRAILNKLIEAEGFEKFLDLKYTGTKRFGLDGGESMVPAMEQIIKRGGALGVEEI 296
Query: 2160 VIGMPHRGRLNVLANVCRQPLATILSQFS--TLEPAD-EGSGDVKYHLGVCIERLNRQSQ 1990
V+GM HRGRLNVL NV +P + +F + PA+ EGSGDVKYHLG +R
Sbjct: 297 VLGMAHRGRLNVLTNVMAKPFRAVFHEFKGGSASPAEVEGSGDVKYHLGASSDRAF--DD 354
Query: 1989 KNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDR--TMAILLHGDAAFAGQGVVL 1816
V +++ ANPSHLE VDPVV+GKVRA+ +R + +L+HGDAAFAGQGVV
Sbjct: 355 NTVHLSLTANPSHLEIVDPVVLGKVRAKQDQKAKPNVERRRVLPLLIHGDAAFAGQGVVA 414
Query: 1815 ETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPE 1636
E L L + T G+IH ++NNQIGFTTDPR SRSSPY +DV ++V PIFH N DDPE
Sbjct: 415 ECLGLSGLKGHRTGGSIHFIINNQIGFTTDPRFSRSSPYPSDVAKMVEAPIFHCNGDDPE 474
Query: 1635 AVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQ 1456
AV VA ++R+ F K V++D++CYRR GHNE DEP FTQP MYQRI++ TALE Y
Sbjct: 475 AVTFAAKVAVEYRQKFGKPVVIDMLCYRRFGHNEGDEPAFTQPKMYQRIRKHPTALETYG 534
Query: 1455 EKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNR-DWLDSPWDDFFKKRDPLK 1279
+K++ +G ++ + ++ +ILE E A Y N+ DWLD W F R+ +
Sbjct: 535 KKLVAQGDLTQEQLDARKAEFRAILESELEVAG--GYKPNKADWLDGRWSGFKAVREDVD 592
Query: 1278 LP---STGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKDN-SLDWACGEALA 1111
P TG + + P GF+LHR ++R R + ++ +DWA EALA
Sbjct: 593 DPRRGRTGVPLETLRDIATRITTPPPGFHLHRTIQRFFDNRAKAVETGVGIDWATAEALA 652
Query: 1110 FGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSL 931
FGSLL EG VRLSGQDV+RGTFS RH V+ DQ+ +Q+ Y PLN L EGQ V NS L
Sbjct: 653 FGSLLIEGHRVRLSGQDVERGTFSQRHAVVIDQENEQR-YTPLNSLREGQANLEVINSML 711
Query: 930 SEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLP 751
SE AVLGFE GYS+ +PNSLV+WEAQFGDF+N AQ +IDQFISSG+ KW+R SGLVMLLP
Sbjct: 712 SEEAVLGFEYGYSLAEPNSLVLWEAQFGDFANGAQVVIDQFISSGERKWLRMSGLVMLLP 771
Query: 750 HGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANI 571
HGYEG GPEHSSAR ER+LQMC ED N VANC+TP+N
Sbjct: 772 HGYEGQGPEHSSARLERYLQMCAED----------------------NMQVANCSTPSNY 809
Query: 570 YHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVI------PETGAPS 409
+H+LRRQ+ FRKP ++ +PKSLLRH A S +ED GS F R++ E G
Sbjct: 810 FHILRRQLKRDFRKPLILMTPKSLLRHKRAVSKIEDIADGSTFHRILWDDAEHDENGVKL 869
Query: 408 QNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAE 229
++RVV C+GKVYYD+ R+ G NDV L+RVEQL PFP + E +++ AE
Sbjct: 870 VRDDKIRRVVLCSGKVYYDLYEEREKRG-VNDVYLMRVEQLYPFPLKALANEMTRFRNAE 928
Query: 228 ILWAQEEHKNMGAWSFVQPRINSLLSIDGRATK---YAGRLPSSSPATGNKFTHMQEQKE 58
++W QEE KNMG+W+FV+P ++ +L G A+K Y GR S+S A G H+ + +
Sbjct: 929 VVWCQEEPKNMGSWTFVEPYLDWVLGQAGSASKRARYVGRPASASTAVGLMSKHLAQLQA 988
Query: 57 MMSKVFGV 34
+++ V
Sbjct: 989 FLNEALAV 996
>gi|45916778|ref|ZP_00195799.2| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Mesorhizobium sp. BNC1]
Length = 994
Score = 754 bits (1946), Expect = 0.0
Identities = 432/1013 (42%), Positives = 589/1013 (57%), Gaps = 45/1013 (4%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAG----A 2773
FL G ++ YIE +Y ++ DPSSV W +F ++ G A
Sbjct: 16 FLYGGNAAYIEDLYASYESDPSSVSDDWRTFFSQLKDNAADVKKSARGASWKQKGWPLTA 75
Query: 2772 LGVSPAAAQVTTSSAPAT---RLDTNASVQSIS-----------DHLKIQLLIRSYQTRG 2635
G +A + +L A+ IS D ++ ++IR+Y+ RG
Sbjct: 76 NGELVSALDGDWGALEGNIDLKLKKKAAEGGISLSEAELQRATRDSVRAIMMIRAYRMRG 135
Query: 2634 HNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREIL 2455
H ADLDPLG+ D EL YG E D DR + + ++ T+RE+L
Sbjct: 136 HLHADLDPLGLAKPMEDYN---ELSPEAYGFTEADFDRPIFIDNVLGL---ETATIREML 189
Query: 2454 QRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAP-RVTELSHDQKKVLFKRLIRSTKFEE 2278
L+ YC++ GVE+MH++N E++ WI+ R E P + + + KK + ++LI S FE+
Sbjct: 190 AILRRTYCSTLGVEFMHISNPEEKAWIQERIEGPDKGVAFTANGKKAILQKLIESEGFEQ 249
Query: 2277 FLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPL 2098
FL K+ KRFGL+G E LIPA++Q+I LG+ V+GM HRGRLNVL+ V +P
Sbjct: 250 FLDVKYKGTKRFGLDGSESLIPALEQIIKRGGQLGLKEIVLGMAHRGRLNVLSQVMGKPH 309
Query: 2097 ATILSQFS--TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVV 1927
I +F + P + EGSGDVKYHLG +R V +++ ANPSHLE V+PVV
Sbjct: 310 RAIFHEFKGGSFTPDEVEGSGDVKYHLGASSDR--EFDGNKVHLSLTANPSHLEIVNPVV 367
Query: 1926 MGKVRA---EAFYAGDEKC------DRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTH 1774
MGK RA + F E+ R M +L+HGDAAFAGQGVV E L L +
Sbjct: 368 MGKARAKQDQLFGRTREEIIPLAERSRVMPLLIHGDAAFAGQGVVAECLGLSGLRGHRVA 427
Query: 1773 GAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRK 1594
G +H+++NNQIGFTT+PR SRSSPY +DV +++ PIFHVN DDPEAV++ VA ++R
Sbjct: 428 GTVHVIINNQIGFTTNPRFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVYAAKVATEFRM 487
Query: 1593 TFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYV 1414
F+K V++D+ CYRR GHNE DEP FTQP+MY+ I+ T +E Y K+++EG+ + +
Sbjct: 488 AFQKPVVIDMFCYRRFGHNEGDEPAFTQPIMYRTIRSHPTTVEVYSRKLIDEGLVTKDDI 547
Query: 1413 KEELTKYGSILEDAYENAQKVTYVRNR-DWLDSPWDDFFK--KRDPLKLPSTGXXXXXXX 1243
+ ++ + LE ++ Q +Y N+ DWLD W K D + T
Sbjct: 548 DQMRAEWRATLEAEFDAGQ--SYKPNKADWLDGAWSGLKKADDGDEQRRGKTAVPVKTLK 605
Query: 1242 XXIGKFSQYPEGFNLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSG 1066
K ++ P F +HR + R L+ R+QM++ +DWA EALAFGS+L EG VRLSG
Sbjct: 606 EIGKKLTEVPADFEVHRTVRRFLENRKQMIETGEGIDWATAEALAFGSILIEGNPVRLSG 665
Query: 1065 QDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMV 886
QD +RGTFS RH VL+DQ+ D+ Y PLN L Q Y V NS LSE AVLGFE GYS+
Sbjct: 666 QDSERGTFSQRHSVLYDQR-DENRYIPLNHLGPQQAYYDVINSMLSEEAVLGFEYGYSLA 724
Query: 885 DPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARP 706
+P +L +WEAQFGDF+N AQ + DQFISSG+ KW+R SGLV LLPHGYEG GPEHSSAR
Sbjct: 725 EPRALTLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGYEGQGPEHSSARL 784
Query: 705 ERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKP 526
ERFLQ+C ED N VANCTTPAN +H+LRRQ+ FRKP
Sbjct: 785 ERFLQLCAED----------------------NMQVANCTTPANYFHILRRQLKRDFRKP 822
Query: 525 AVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPP-------DVKRVVFCTG 367
++ +PKSLLRH A S + + S F R++ + QN P ++RVV C+G
Sbjct: 823 LILMTPKSLLRHKRAVSTLAEMSGESTFHRLLWDDAQSLQNQPIKLVKDSKIRRVVMCSG 882
Query: 366 KVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAW 187
KVYYD+ R+ G NDV L+RVEQL PFP + E +++ AE++W QEE KNMGAW
Sbjct: 883 KVYYDLYEEREKRG-INDVYLLRVEQLYPFPAKALITELSRFRNAEMVWCQEEPKNMGAW 941
Query: 186 SFVQPRINSLL---SIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFG 37
SF+ P + +L + +YAGR S+SPATG H+++ +++ G
Sbjct: 942 SFIDPYLEWVLQHIEAKNKRVRYAGRPASASPATGLMSKHLEQLGQLLEDALG 994
>gi|27375563|ref|NP_767092.1| alpha-ketoglutarate dehydrogenase
[Bradyrhizobium japonicum USDA 110]
gi|27348700|dbj|BAC45717.1| alpha-ketoglutarate dehydrogenase
[Bradyrhizobium japonicum USDA 110]
Length = 985
Score = 753 bits (1943), Expect = 0.0
Identities = 432/1014 (42%), Positives = 588/1014 (57%), Gaps = 38/1014 (3%)
Frame = -1
Query: 2973 QSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYF-----------RNVEXX 2827
Q AA FL G+++ YI+++Y + +DPSSV W +F RN E
Sbjct: 4 QDANAAFALSSFLQGTNATYIDEIYARYEKDPSSVDAEWQEFFKSLKDQPDDVRRNAEGP 63
Query: 2826 XXXXXXXXXXXXXAYAGALG-----VSPAAAQVTTSSAPATRLDTNAS--VQSISDHLKI 2668
AL V A + A A D +++ +Q+ D ++
Sbjct: 64 SWERANWPLTPQDDLTSALDGNWAEVEKAVGGKIAAKAQAKGADISSADLLQATRDSVRA 123
Query: 2667 QLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFIS 2488
+LIRSY+ RGH A LDPLGI + + + P YG E D DR+ L +
Sbjct: 124 LMLIRSYRMRGHFHAKLDPLGIEAPRNREELDPRT----YGFSEADFDRKIFLDHVLGLE 179
Query: 2487 EKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAP-RVTELSHDQKKVLF 2311
TLREI + YC + GVE+MH++N Q+ WI+ R E P + + + ++ +
Sbjct: 180 YG---TLREITAICERTYCQTLGVEFMHISNAAQKAWIQERIEGPDKEISFTREGRRAIL 236
Query: 2310 KRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRL 2131
+L+ + FE+F K+ KRFGL+G E LIPA++Q+I LGV V+GMPHRGRL
Sbjct: 237 TKLVEAEGFEKFCDTKFTGTKRFGLDGAESLIPALEQIIKRGGNLGVKEIVLGMPHRGRL 296
Query: 2130 NVLANVCRQPLATILSQF---STLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVAN 1960
NVL V + + +F S A EGSGDVKYHLG +R + +++ AN
Sbjct: 297 NVLTQVMGKAHRALFHEFKGGSANPDAVEGSGDVKYHLGASSDR--EFDGNRIHLSLTAN 354
Query: 1959 PSHLEAVDPVVMGKVRAEAFYAGDEKCDR--TMAILLHGDAAFAGQGVVLETFNLDDLPS 1786
PSHLE VDPVV+GKVRA+ GD R M +L+HGDAAFAGQGVV E F L DL
Sbjct: 355 PSHLEIVDPVVLGKVRAKQDQHGDPPDMRISVMPLLMHGDAAFAGQGVVAECFGLSDLKG 414
Query: 1785 YTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAA 1606
Y T G++H +VNNQIGFTT PR SRSSPY +DV +++ PIFHVN DDPEAV+ VA
Sbjct: 415 YRTGGSVHFIVNNQIGFTTYPRYSRSSPYPSDVAKMIDAPIFHVNGDDPEAVVFAAKVAT 474
Query: 1605 DWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVAN 1426
++R+ F K V++D+ CYRRHGHNE DEP FTQP+MY++I + LE Y ++++EGV
Sbjct: 475 EFRQKFHKPVVIDMFCYRRHGHNEGDEPAFTQPVMYKKIAAHPSTLELYARRLISEGVMT 534
Query: 1425 EQYVKEELTKYGSILEDAYENAQKVTYVRNR-DWLDSPWDDF--FKKRDPLKLPSTGXXX 1255
E V + + + L+ +E +Y N+ DWLD W F + + + TG
Sbjct: 535 EGEVDKAKADWRARLDAEFEAG--TSYKPNKADWLDGKWAGFKIADQEEDARRGVTGVDI 592
Query: 1254 XXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKDNS-LDWACGEALAFGSLLKEGIHV 1078
K ++ P+GF +HR ++R L+ R + + + +DWA GEALAF SLL E HV
Sbjct: 593 TALKDIGRKITKVPDGFRVHRTIQRFLENRSKAIDSGAGIDWATGEALAFCSLLNENHHV 652
Query: 1077 RLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELG 898
RLSGQD +RGTFS RH VL DQ+ D+ Y P N L QG Y V NS LSE AVLGFE G
Sbjct: 653 RLSGQDSERGTFSQRHSVLIDQE-DESRYTPFNHLGHEQGHYEVINSLLSEEAVLGFEYG 711
Query: 897 YSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHS 718
YS+ +PN+L +WEAQFGDF+N AQ + DQFISSG+ KW+R SGLV LLPHGYEG GPEHS
Sbjct: 712 YSLAEPNTLTLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGYEGQGPEHS 771
Query: 717 SARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMP 538
SAR ER+LQMC ED N V TTPAN +H+LRRQ+
Sbjct: 772 SARLERYLQMCAED----------------------NMQVVYPTTPANYFHVLRRQLHRE 809
Query: 537 FRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPE------TGAPSQNPPD-VKRVV 379
RKP ++ +PKSLLRH A S +E+ G+ F R++ + T A P + ++R+V
Sbjct: 810 IRKPLILMTPKSLLRHKRAVSRLEELAKGTTFHRILYDDAQMLPTDAIKLVPDEKIRRIV 869
Query: 378 FCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKN 199
C+GKVYYD+ R+ G + D+ L+RVEQL P P + E +++ AE++W QEE +N
Sbjct: 870 LCSGKVYYDLYEEREKRGID-DIYLMRVEQLYPVPLKALVAELSRFKKAEVVWCQEEPRN 928
Query: 198 MGAWSFVQPRINSLLS-IDG--RATKYAGRLPSSSPATGNKFTHMQEQKEMMSK 46
MGAW F++P + +L+ ++G R +Y GR S++ ATG H + K + +
Sbjct: 929 MGAWHFIEPYLEWVLNQVNGVSRRPRYVGRAASAATATGLMSKHQAQLKAFLDE 982
>gi|48141298|ref|XP_397207.1| similar to CG11661-PA [Apis mellifera]
Length = 727
Score = 752 bits (1941), Expect = 0.0
Identities = 375/726 (51%), Positives = 494/726 (67%), Gaps = 6/726 (0%)
Frame = -1
Query: 2208 MKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVKYH 2029
M Q +++S+ GV+S VIGM HRGRLN L NVC +PL +L+QF ++ GSGDVKYH
Sbjct: 1 MNQCLETSAEHGVESVVIGMAHRGRLNTLINVCMKPLHQLLTQFHSIALEGFGSGDVKYH 60
Query: 2028 LGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGD-EKCDRTMAILLH 1852
LG ER+ +SQK +++A++ANPSHLEA+DPVV+G+VRAE D E +++A L+H
Sbjct: 61 LGTHAERMLERSQKQIRVAMMANPSHLEAIDPVVVGRVRAEQVEKNDAEFGKKSVAFLVH 120
Query: 1851 GDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVG 1672
GDAAF+GQG+V ET +L +LP+YTT G IHIV+NNQIGFTTDPR SRSS +CTDV RVV
Sbjct: 121 GDAAFSGQGIVYETMHLTNLPNYTTGGVIHIVINNQIGFTTDPRYSRSSAHCTDVARVVN 180
Query: 1671 CPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQR 1492
PIFH++ DDP+ V + VA+++R F DV+VD+V YRR GHNELDEPM TQPLMY+R
Sbjct: 181 APIFHIHADDPDLVTYCSKVASEYRAEFHNDVVVDIVGYRRFGHNELDEPMLTQPLMYKR 240
Query: 1491 IKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPW 1312
IKQ L Y +K+ EGV E + KEE+ KY + E +E A+ + ++ DW D PW
Sbjct: 241 IKQHPNVLNIYSDKLFKEGVITEAFAKEEIEKYWNYCETEFEKAKTIDSMQLGDWHDVPW 300
Query: 1311 DDFFKKRDPL-KLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKDNSLD 1135
DFF + P K+P TG S P H + R ++ R Q+ K D
Sbjct: 301 SDFFATQSPKNKIPPTGIDIETIKTICKAISTPPNDIESHTQVLRVMEKRAQLSKSRQAD 360
Query: 1134 WACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGE 955
WA GE LAF SLLKEG VRLSG+DV+RGTFSHR HV+HDQ D+ N L+D+ GQ
Sbjct: 361 WAMGECLAFSSLLKEGCPVRLSGEDVERGTFSHRTHVIHDQSRDKTYKNILHDIFPGQAM 420
Query: 954 YTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQ 775
YTV NSSLSEY V GFE+GYS + N+L IWEAQFGDF+NT Q +D +SSGQ+KW RQ
Sbjct: 421 YTVTNSSLSEYGVCGFEVGYSTYNHNTLTIWEAQFGDFANTCQVTLDTILSSGQTKWGRQ 480
Query: 774 SGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEG----TFEAQQLHDTN 607
GLV+LLPHG EG GPEHSSA+ ER+L++C DD+ A G +QL + N
Sbjct: 481 VGLVLLLPHGLEGQGPEHSSAKIERYLELC--DDDFSYLPTAEPGETIDQIMTRQLFEIN 538
Query: 606 WIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIP 427
WI+ N TTPAN +H+LRRQ+ MPFRKP + +PKSLLRHPMA SP D +SG++F+ ++
Sbjct: 539 WIICNLTTPANFFHVLRRQIHMPFRKPLCIMTPKSLLRHPMALSPFADMESGTSFKPILS 598
Query: 426 ETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECR 247
+ P P ++++V+ C+G+V+YD+V R+ + +A++R+EQL PFPY L+ +E +
Sbjct: 599 D---PFVKPGNIQKVLMCSGRVFYDLVTERQGKQLVDKIAIIRIEQLCPFPYHLLAEEMK 655
Query: 246 KYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQE 67
KY A+++W QEEHKN G + +V+ RI L I Y GR PSSSPATG+K H E
Sbjct: 656 KYPNAKLMWLQEEHKNQGPYLYVRDRIALALGIRLEDLAYGGRPPSSSPATGSKVIHRNE 715
Query: 66 QKEMMS 49
+M++
Sbjct: 716 YNDMIT 721
>gi|39933266|ref|NP_945542.1| putative alpha-ketoglutarate
dehydrogenase (E1 subunit) [Rhodopseudomonas palustris
CGA009]
gi|39652891|emb|CAE25633.1| putative alpha-ketoglutarate
dehydrogenase (E1 subunit) [Rhodopseudomonas palustris
CGA009]
Length = 985
Score = 751 bits (1939), Expect = 0.0
Identities = 436/1018 (42%), Positives = 595/1018 (57%), Gaps = 42/1018 (4%)
Frame = -1
Query: 2973 QSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFR-----------NVEXX 2827
Q AA FL G+++ YI+ +Y + DPSSV W A+FR N E
Sbjct: 4 QDANAAFALSSFLQGANATYIDDLYSRYESDPSSVDADWQAFFRSLKDAPGDIQKNAEGP 63
Query: 2826 XXXXXXXXXXXXXAYAGALG-----VSPAAAQVTTSSAPATRLDTNAS--VQSISDHLKI 2668
AL V A Q + A + ++ +++ +Q+ D ++
Sbjct: 64 SWEQANWPLTPRDELTSALDGNWNQVEKAVGQKIQAKAQSRGVELSSADVLQATRDSVRA 123
Query: 2667 QLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFIS 2488
+LIR+Y+ RGH A LDPLG++ A + EL++ YG E DLDR+ L +
Sbjct: 124 LMLIRAYRMRGHFHAKLDPLGLSPAKDHE----ELDIRSYGFTEADLDRKIFLDHVLGLE 179
Query: 2487 EKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAP-RVTELSHDQKKVLF 2311
+LREI+ + YC + G+E++H++N Q+ WI+ R E P + + + ++ +
Sbjct: 180 YG---SLREIVAICERTYCQTMGIEFLHISNGAQKAWIQERIEGPDKEISFTREGRRAIL 236
Query: 2310 KRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRL 2131
+LI S FE+F K+ KRFGL+G E LIPA++Q+I LGV V+GMPHRGRL
Sbjct: 237 MKLIESEGFEKFCDLKFTGTKRFGLDGGEALIPALEQIIKRGGNLGVREIVLGMPHRGRL 296
Query: 2130 NVLANVCRQPLATILSQFS--TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVAN 1960
NVL V + + +F + P + EGSGDVKYHLG +R V +++ AN
Sbjct: 297 NVLTQVMAKAHRALFHEFKGGSANPDEVEGSGDVKYHLGASSDR--EFDHNKVHLSLTAN 354
Query: 1959 PSHLEAVDPVVMGKVRAEAFYAGDEKCDR--TMAILLHGDAAFAGQGVVLETFNLDDLPS 1786
PSHLE VDPVV+GKVRA+ GD +R + +L+HGDAAFAGQGVV E F L DL
Sbjct: 355 PSHLEIVDPVVLGKVRAKQDQHGDLPEERISVLPLLMHGDAAFAGQGVVAECFALSDLKG 414
Query: 1785 YTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAA 1606
Y T G+IH +VNNQIGFTT PR SRSSPY +DV +++ PIFHVN DDPEAV+ +A
Sbjct: 415 YRTGGSIHFIVNNQIGFTTYPRYSRSSPYPSDVAKMIDAPIFHVNGDDPEAVVFAAKIAV 474
Query: 1605 DWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVAN 1426
++R+ F K V++D+ CYRRHGHNE DEP FTQPLMY++I T LE Y ++++ +GV
Sbjct: 475 EYRQKFHKPVVIDMFCYRRHGHNEGDEPSFTQPLMYRKIAGHPTTLEIYSKRLIADGVIT 534
Query: 1425 EQYVKEELTKYGSILEDAYENAQKVTYVRNR-DWLDSPWDDFFKKRDPLKLPS---TGXX 1258
E V++ + + L+ +E A +Y N+ DWLD W FK D + P TG
Sbjct: 535 EGEVEKARADWRARLDAEFEAAS--SYRPNKADWLDGKWAG-FKSADQEEEPRRGITGVD 591
Query: 1257 XXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQML-KDNSLDWACGEALAFGSLLKEGIH 1081
+ ++ PEGF LHR ++R L+ R + + N LDWA GEALAF ++L EG
Sbjct: 592 LPTLKEIGRRITKVPEGFRLHRTVQRFLENRARAIDSGNGLDWATGEALAFCTMLLEGHR 651
Query: 1080 VRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFEL 901
+RLSGQD +RGTFS RH VL DQ+ D+ Y P N LS QG Y V NS LSE AVLGFE
Sbjct: 652 IRLSGQDSERGTFSQRHSVLIDQE-DETRYTPFNHLSPDQGHYEVINSLLSEEAVLGFEY 710
Query: 900 GYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEH 721
GYS+ +PN+L +WEAQFGDF+N AQ + DQFISSG+ KW+R SGLV LLPHGYEG GPEH
Sbjct: 711 GYSLAEPNALTLWEAQFGDFANGAQVLFDQFISSGERKWLRMSGLVCLLPHGYEGQGPEH 770
Query: 720 SSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTM 541
SSAR ER+LQMC ED N V TTPAN +H LRRQ+
Sbjct: 771 SSARLERYLQMCAED----------------------NMQVVYPTTPANYFHALRRQLKR 808
Query: 540 PFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPD----------V 391
RKP ++ +PKSLLRH A S +E+ ++F RV+ + +Q PD +
Sbjct: 809 EIRKPLILMTPKSLLRHKRAISRLEELGPDTSFHRVLLD---DAQTLPDDKTKLVADAKI 865
Query: 390 KRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQE 211
+RVV C+GKVYYD+ R+ G + DV L+RVEQL P P + E +++ AE++W QE
Sbjct: 866 RRVVVCSGKVYYDLYDEREKRGID-DVYLLRVEQLYPVPVKTLVHELSRFKDAELVWCQE 924
Query: 210 EHKNMGAWSFVQPR---INSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSK 46
E +NMG W F++P + + + R +Y GR S++ ATG H+ + K + +
Sbjct: 925 EPRNMGGWHFIEPYLEWVQNQIEAKHRRPRYVGRAASAATATGLMSKHLAQLKAFLDE 982
>gi|1765991|gb|AAC44748.1| alpha-ketoglutarate dehydrogenase
[Bradyrhizobium japonicum]
Length = 985
Score = 747 bits (1929), Expect = 0.0
Identities = 430/1014 (42%), Positives = 587/1014 (57%), Gaps = 38/1014 (3%)
Frame = -1
Query: 2973 QSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYF-----------RNVEXX 2827
Q AA FL G+++ YI+++Y + +DPSSV W +F RN E
Sbjct: 4 QDANAAFALSSFLQGTNATYIDEIYARYEKDPSSVDAEWQEFFKSLKDQPDDVRRNAEGP 63
Query: 2826 XXXXXXXXXXXXXAYAGALG-----VSPAAAQVTTSSAPATRLDTNAS--VQSISDHLKI 2668
AL V A + A A D +++ +Q+ D ++
Sbjct: 64 SWERANWPLTPQDDLTSALDGNWAEVEKAVGGKIAAKAQAKGADISSADLLQATRDSVRA 123
Query: 2667 QLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFIS 2488
+LIRS++ RGH A LDPLGI + + + P YG E D DR+ L +
Sbjct: 124 LMLIRSHRMRGHFHAKLDPLGIEAPRNREELDPRT----YGFSEADFDRKIFLDHVLGLE 179
Query: 2487 EKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAP-RVTELSHDQKKVLF 2311
TLREI + YC + GVE+MH++N Q+ WI+ R E P + + + ++ +
Sbjct: 180 YG---TLREITAICERTYCQTLGVEFMHISNAAQKAWIQERIEGPDKEISFTREGRRAIL 236
Query: 2310 KRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRL 2131
+L+ + FE+F K+ KRFGL+G E LIPA++Q+I LGV V+GMPHRGRL
Sbjct: 237 TKLVEAEGFEKFCDTKFTGTKRFGLDGAESLIPALEQIIKRGGNLGVKEIVLGMPHRGRL 296
Query: 2130 NVLANVCRQPLATILSQF---STLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVAN 1960
NVL V + + +F S A EGSGDVKYHLG +R + +++ AN
Sbjct: 297 NVLTQVMGKAHRALFHEFKGGSANPDAVEGSGDVKYHLGASSDR--EFDGNRIHLSLTAN 354
Query: 1959 PSHLEAVDPVVMGKVRAEAFYAGDEKCDR--TMAILLHGDAAFAGQGVVLETFNLDDLPS 1786
PSHLE VDPVV+GKVRA+ GD R M +L+HGDAAFAGQGVV E F L DL
Sbjct: 355 PSHLEIVDPVVLGKVRAKQDQHGDPPDMRISVMPLLMHGDAAFAGQGVVAECFGLSDLKG 414
Query: 1785 YTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAA 1606
Y T G++H +VNNQIGFTT P SRSSPY +DV +++ PIFHVN DDPEAV+ VA
Sbjct: 415 YRTGGSVHFIVNNQIGFTTYPCYSRSSPYPSDVAKMIDAPIFHVNGDDPEAVVFAAKVAT 474
Query: 1605 DWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVAN 1426
++R+ F K V++D+ CYRRHGHNE DEP FTQP+MY++I + LE Y ++++EGV
Sbjct: 475 EFRQKFHKPVVIDMFCYRRHGHNEGDEPAFTQPVMYKKIAAHPSTLELYARRLISEGVMT 534
Query: 1425 EQYVKEELTKYGSILEDAYENAQKVTYVRNR-DWLDSPWDDF--FKKRDPLKLPSTGXXX 1255
E V + + + L+ +E +Y N+ DWLD W F + + + TG
Sbjct: 535 EGEVDKAKADWRARLDAEFEAG--TSYKPNKADWLDGKWAGFKIADQEEDARRGVTGVDI 592
Query: 1254 XXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKDNS-LDWACGEALAFGSLLKEGIHV 1078
K ++ P+GF +HR ++R L+ R + + + +DWA GEALAF SLL E HV
Sbjct: 593 NALKDIGRKITKVPDGFRVHRTIQRFLENRSKAIDSGAGIDWATGEALAFCSLLNENHHV 652
Query: 1077 RLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELG 898
RLSGQD +RGTFS RH VL DQ+ D+ Y P N L QG Y V NS LSE AVLGFE G
Sbjct: 653 RLSGQDSERGTFSQRHSVLIDQE-DESRYTPFNHLGHEQGHYEVINSLLSEEAVLGFEYG 711
Query: 897 YSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHS 718
YS+ +PN+L +WEAQFGDF+N AQ + DQFISSG+ KW+R SGLV LLPHGYEG GPEHS
Sbjct: 712 YSLAEPNTLTLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGYEGQGPEHS 771
Query: 717 SARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMP 538
SAR ER+LQMC ED N V TTPAN +H+LRRQ+
Sbjct: 772 SARLERYLQMCAED----------------------NMQVVYPTTPANYFHVLRRQLHRE 809
Query: 537 FRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPE------TGAPSQNPPD-VKRVV 379
RKP ++ +PKSLLRH A S +E+ G+ F R++ + T A P + ++R+V
Sbjct: 810 IRKPLILMTPKSLLRHKRAVSRLEELAKGTTFHRILYDDAQMLPTDAIKLVPDEKIRRIV 869
Query: 378 FCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKN 199
C+GKVYYD+ R+ G + D+ L+RVEQL P P + E +++ AE++W QEE +N
Sbjct: 870 LCSGKVYYDLYEEREKRGID-DIYLMRVEQLYPVPLKALVAELSRFKKAEVVWCQEEPRN 928
Query: 198 MGAWSFVQPRINSLLS-IDG--RATKYAGRLPSSSPATGNKFTHMQEQKEMMSK 46
MGAW F++P + +L+ ++G R +Y GR S++ ATG H + K + +
Sbjct: 929 MGAWHFIEPYLEWVLNQVNGVSRRPRYVGRAASAATATGLMSKHQAQLKAFLDE 982
>gi|16124594|ref|NP_419158.1| 2-oxoglutarate dehydrogenase, E1
component [Caulobacter crescentus CB15]
gi|25284465|pir||B87291 2-oxoglutarate dehydrogenase, E1 component
[imported] - Caulobacter crescentus
gi|13421488|gb|AAK22326.1| 2-oxoglutarate dehydrogenase, E1 component
[Caulobacter crescentus CB15]
Length = 976
Score = 743 bits (1917), Expect = 0.0
Identities = 416/1008 (41%), Positives = 580/1008 (57%), Gaps = 41/1008 (4%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
FL G+++ ++E +Y W ++P SV SW+A+F +++ V
Sbjct: 6 FLYGANAAFVEDLYAQWAENPGSVEPSWNAFFASLQEQADQVKRAAQDPAWTPKKVATVR 65
Query: 2760 P----AAAQVTTSSAPATRLDTNASVQSIS-------------DHLKIQLLIRSYQTRGH 2632
P A + APA + ++++ + D L+ ++IR+Y+ RGH
Sbjct: 66 PDWLSALDGQWATVAPAVEAKVSKAIEAKAPAASAEAVRAATLDSLRAIMMIRAYRMRGH 125
Query: 2631 NIADLDPLGINSADLDDTIPP----ELELSFYGLGERDLDREFLLPPTTFISEKKSLTLR 2464
A+LDPLG++ PP EL+ + YG E D DR L F+ ++ T+R
Sbjct: 126 LAANLDPLGLD--------PPKDASELDPASYGFSEADYDRPIFLD---FVLGLETATIR 174
Query: 2463 EILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEA-PRVTELSHDQKKVLFKRLIRSTK 2287
EIL ++ YC + GV+YMH+++ ++ W++ R E + S + K + K+LI +
Sbjct: 175 EILSIVRRTYCGNVGVQYMHISDPAEKAWLQERIEGRDKEITFSKEGKVAILKKLIEAEG 234
Query: 2286 FEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCR 2107
FE FL K++P KRFGL+G E ++PA++Q+I LGV V+GMPHRGRLNVLA V
Sbjct: 235 FERFLHKRFPGTKRFGLDGGEAMVPALEQIIKRGGALGVKDIVLGMPHRGRLNVLAAVMG 294
Query: 2106 QPLATILSQFS--TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVD 1936
+P I +F + P+D EGSGDVKYH+G +R V +++ ANPSHLE V+
Sbjct: 295 KPYHVIFHEFQGGSSVPSDVEGSGDVKYHMGASSDR--EFDDNKVHLSLTANPSHLEIVN 352
Query: 1935 PVVMGKVRAEAFYAGDEKCD----RTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGA 1768
PVV+GK RA+ + E+ D + +LLHGDAAFAGQGVV E F L L Y T G
Sbjct: 353 PVVIGKARAKQAFTLREQPDAGRGHVLPLLLHGDAAFAGQGVVAECFTLSGLKGYRTGGT 412
Query: 1767 IHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTF 1588
IH +VNNQIGFTT PR SRSSPY +D+ +V PIFHVN DDPEAV+ V+ ++R+ F
Sbjct: 413 IHFIVNNQIGFTTSPRYSRSSPYPSDMALMVEAPIFHVNGDDPEAVVFAAKVSTEYRQKF 472
Query: 1587 KKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKE 1408
KDV++D+VCYRR GHNE D+P T PLMY +IK + E Y +++ EGV +
Sbjct: 473 GKDVVIDMVCYRRFGHNEGDDPTMTSPLMYAKIKGHPSTRELYSNRLIGEGVITQADCDS 532
Query: 1407 ELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGK 1228
++++ L DA +A K+ DWLD W D + T
Sbjct: 533 WVSEFEKFL-DAEFDAGKIYKPNKADWLDGKWAGLTLPGDEDRRGKTAFPKTRLLELGRL 591
Query: 1227 FSQYPEGFNLHRGLERTLKGRQQML-KDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQR 1051
+ PE + H+ + R ++ R+ K +DW E LAF +LL EGI VRLSGQD R
Sbjct: 592 ITAIPERIDAHKTVRRAIENRRDAFEKGEGIDWGAAEHLAFATLLDEGIPVRLSGQDSVR 651
Query: 1050 GTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSL 871
GTF+ RH + DQK ++ Y PLN++ GQ Y V +S+LSE AVLGFE G+S+ +PN+L
Sbjct: 652 GTFTQRHSDIIDQKTEEH-YTPLNNIRAGQAHYEVIDSALSEEAVLGFEYGFSLAEPNTL 710
Query: 870 VIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQ 691
+WE QFGDF N AQ +IDQFISSG+ KW+R SGLVMLLPHGYEG GPEHSSAR ERFLQ
Sbjct: 711 TLWEGQFGDFVNGAQVVIDQFISSGERKWLRMSGLVMLLPHGYEGQGPEHSSARLERFLQ 770
Query: 690 MCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFS 511
C ED N V NCTTPAN +H LRRQ+ FRKP +V +
Sbjct: 771 SCAED----------------------NMQVVNCTTPANYFHALRRQMHREFRKPLIVMA 808
Query: 510 PKSLLRHPMARSPVEDFQSGSNFQRVIPE--------TGAPSQNPPDVKRVVFCTGKVYY 355
PKSLLRH A S + DF GS F RV+ + G ++ +KRV+ C+GKVY+
Sbjct: 809 PKSLLRHKRAVSNLSDFAEGSAFHRVMVDGAEAGCDVGGITLKSDDKIKRVIVCSGKVYF 868
Query: 354 DMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQ 175
D+V R +G++ DV L+R+EQ P+P + +++ A+++W QEE +NMG W+FV
Sbjct: 869 DLVDQRAKLGRD-DVYLLRLEQFYPWPMKSLMNVLSRFKNADLIWCQEEPRNMGGWTFVD 927
Query: 174 PRIN---SLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVF 40
P + L I + KY GR S+S A G H++E + +++ F
Sbjct: 928 PWLELTLDKLDIKAKRAKYVGRPASASTAAGLMSRHLKELETFLNEAF 975
>gi|15889891|ref|NP_355572.1| AGR_C_4776p [Agrobacterium tumefaciens
str. C58]
gi|17936511|ref|NP_533301.1| oxoglutarate dehydrogenase E1 component
[Agrobacterium tumefaciens str. C58]
gi|25284475|pir||D97675 2-oxoglutarate dehydrogenase E1 chain
(AY026040) [imported] - Agrobacterium tumefaciens (strain
C58, Cereon)
gi|25284476|pir||AC2900 oxoglutarate dehydrogenase E1 component sucA
[imported] - Agrobacterium tumefaciens (strain C58,
Dupont)
gi|15157840|gb|AAK88357.1| AGR_C_4776p [Agrobacterium tumefaciens
str. C58]
gi|17741137|gb|AAL43617.1| oxoglutarate dehydrogenase E1 component
[Agrobacterium tumefaciens str. C58]
Length = 1016
Score = 742 bits (1915), Expect = 0.0
Identities = 431/1017 (42%), Positives = 593/1017 (57%), Gaps = 49/1017 (4%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFR----NVEXXXXXXXXXXXXXXXAYAGA 2773
FL+G+++ YIEQ+Y + +DPSSV W ++F+ N E A
Sbjct: 33 FLDGANAAYIEQLYARYEEDPSSVSPEWQSFFKALSDNPEDVKKAAKGASWKRANWPIPA 92
Query: 2772 LG------------VSPAAAQVTTSSAPATRLDTNASV------QSISDHLKIQLLIRSY 2647
G V A + + A A DT V Q+ D ++ ++IR+Y
Sbjct: 93 NGELVSALDGNWATVEKAIEKKVQAKAEAKSADTGKPVSEAEVLQATRDSVRAIMMIRAY 152
Query: 2646 QTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTL 2467
+ RGH A LDPLGI SA D EL YG E D DR+ + + + T+
Sbjct: 153 RMRGHLHAKLDPLGIASAVEDYN---ELSPKSYGFEESDYDRKIFIDNVLGL---EYATV 206
Query: 2466 REILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAP-RVTELSHDQKKVLFKRLIRST 2290
RE+++ L+ YC++ GVE+MH++N E++ WI+ R E P + + + + KK + +L+ +
Sbjct: 207 REMVEILERTYCSTLGVEFMHMSNPEEKGWIQERIEGPDKGVDFTPEGKKAILSKLVEAE 266
Query: 2289 KFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVC 2110
+E+FL ++ KRFGL+G E LIPA++Q+I G++ V+GM HRGRLNVL NV
Sbjct: 267 GYEQFLDVRFKGTKRFGLDGGESLIPALEQIIKRGGQDGLEEVVLGMAHRGRLNVLTNVM 326
Query: 2109 RQPLATILSQFS--TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAV 1939
+P + +F + +P D EGSGDVKYHLG +R V +++ ANPSHLE V
Sbjct: 327 GKPHRAVFHEFKGGSFKPDDVEGSGDVKYHLGASSDR--EFDGNKVHLSLTANPSHLEIV 384
Query: 1938 DPVVMGKVRAEA-----FYAGD----EKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPS 1786
+PVVMGK RA+ + GD + + + +LLHGDAAFAGQGVV E L L
Sbjct: 385 NPVVMGKARAKQDQLAKTWDGDIIPLSERAKVLPLLLHGDAAFAGQGVVAEILGLSGLRG 444
Query: 1785 YTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAA 1606
+ G +H ++NNQIGFTT+P SRSSPY +DV +++ PIFHVN DDPEAV++ VA
Sbjct: 445 HRVAGTMHFIINNQIGFTTNPAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVYAAKVAT 504
Query: 1605 DWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVAN 1426
++R F K V++D+ CYRR GHNE DEP FTQP MY+ I+ KT Y ++++ EG+
Sbjct: 505 EYRMKFHKPVVIDMFCYRRFGHNEGDEPAFTQPKMYKVIRGHKTVARIYADRLIAEGLIT 564
Query: 1425 EQYVKEELTKYGSILEDAYENAQKVTYVRNR-DWLDSPWDDF--FKKRDPLKLPSTGXXX 1255
E ++ + + LE +E Q +Y N+ DWLD W D + TG
Sbjct: 565 EGDFEKVKADWRAHLEQEFEAGQ--SYKPNKADWLDGQWSGLRAADNADEQRRGKTGVPM 622
Query: 1254 XXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHV 1078
K S PEGF HR ++R ++ R QM++ +DWA EALAFGSL+ +G +
Sbjct: 623 KQLKEIGKKLSTIPEGFTAHRTIQRFMENRSQMIETGEGIDWAMAEALAFGSLVVDGHKI 682
Query: 1077 RLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELG 898
RLSGQD +RGTFS RH VL+DQ+ +++ Y PL +L+ Q Y V NS LSE AVLGFE G
Sbjct: 683 RLSGQDCERGTFSQRHSVLYDQETEER-YIPLANLAPTQARYEVINSMLSEEAVLGFEYG 741
Query: 897 YSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHS 718
YS+ PN+L +WEAQFGDF+N AQ + DQFISSG+ KW+R SGLV LLPHGYEG GPEHS
Sbjct: 742 YSLARPNALTLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGYEGQGPEHS 801
Query: 717 SARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMP 538
SAR ER+LQMC ED N VAN TTPAN +H+LRRQ+
Sbjct: 802 SARLERWLQMCAED----------------------NMQVANVTTPANYFHILRRQMKRD 839
Query: 537 FRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQR-------VIPETGAPSQNPPDVKRVV 379
FRKP ++ +PKSLLRH A S + + S+F R VI + Q ++RVV
Sbjct: 840 FRKPLILMTPKSLLRHKRATSSLAELAGESSFHRLLWDDAEVIKDGPIKLQKDAKIRRVV 899
Query: 378 FCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKN 199
CTGKVYYD++ R+ G + DV L+RVEQL PFP + E +++ AE++W QEE KN
Sbjct: 900 MCTGKVYYDLLEEREKRGID-DVYLLRVEQLYPFPAKALINELSRFRHAEMVWCQEEPKN 958
Query: 198 MGAWSFVQPRINSLLS-IDGRATK--YAGRLPSSSPATGNKFTHMQEQKEMMSKVFG 37
MG+WSF+ P + +L+ ID + K Y GR ++SPATG H+ + + G
Sbjct: 959 MGSWSFIDPYLEWVLAHIDAKYQKVRYTGRPAAASPATGLMSKHLAQLAAFLEDALG 1015
>gi|15966806|ref|NP_387159.1| PROBABLE 2-OXOGLUTARATE DEHYDROGENASE E1
COMPONENT PROTEIN [Sinorhizobium meliloti 1021]
gi|15076078|emb|CAC47632.1| PROBABLE 2-OXOGLUTARATE DEHYDROGENASE E1
COMPONENT PROTEIN [Sinorhizobium meliloti]
gi|15283981|gb|AAK00591.2| 2-oxoglutarate dehydrogenase E1 subunit
[Sinorhizobium meliloti]
Length = 998
Score = 739 bits (1909), Expect = 0.0
Identities = 421/1017 (41%), Positives = 589/1017 (57%), Gaps = 49/1017 (4%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXX---------- 2791
FL+G+++ YIEQ++ + DPSSV W ++F+ +
Sbjct: 15 FLDGANAAYIEQLHARYEADPSSVSAEWQSFFKALADRPEDVVRAAKGASWKKQNWPIPA 74
Query: 2790 ------------XAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSY 2647
+G A ++ L QS D ++ ++IR+Y
Sbjct: 75 NGELVSALDGDWGTVEKVIGKKVKAKAEEAAAVAGVALSEAEVHQSTRDSVRAIMMIRAY 134
Query: 2646 QTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTL 2467
+ RGH A LDPLG+ D EL YG E+D DR+ + + + T+
Sbjct: 135 RMRGHLHAKLDPLGLADPVEDYD---ELSPKTYGFEEKDYDRKIFIDNVLGL---EYATV 188
Query: 2466 REILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAP-RVTELSHDQKKVLFKRLIRST 2290
RE+++ L+ YC++ GVE+MH++N E++ WI+ R E P + E + + KK + ++LI +
Sbjct: 189 REMVEILERTYCSTIGVEFMHMSNPEEKGWIQERIEGPDKGVEFTPEGKKAILQKLIEAE 248
Query: 2289 KFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVC 2110
FE+F+ K+ KRFG++G E LIPA++Q+I LG+ V+GM HRGRLNVL+ V
Sbjct: 249 GFEQFIDVKYKGTKRFGVDGGESLIPALEQIIKRGGQLGLKEIVLGMAHRGRLNVLSQVM 308
Query: 2109 RQPLATILSQFS--TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAV 1939
+P I +F + P D EGSGDVKYHLG +R V +++ ANPSHLE V
Sbjct: 309 AKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDR--EFDGNKVHLSLTANPSHLEIV 366
Query: 1938 DPVVMGKVRAE-----AFYAGD----EKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPS 1786
+PVVMGK RA+ + GD + + M ++LHGDAAFAGQGVV E L L
Sbjct: 367 NPVVMGKARAKQDQMATVFEGDIIPLRERVKVMPLILHGDAAFAGQGVVAEILGLSGLRG 426
Query: 1785 YTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAA 1606
+ G +H ++NNQIGFTT+P SRSSPY +DV +++ PIFHVN DDPEAV++ VA
Sbjct: 427 HRVGGTVHFIINNQIGFTTNPAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVYAAKVAT 486
Query: 1605 DWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVAN 1426
++R F K V++D+ CYRR GHNE DEP FTQP MY+ I+ KT ++ Y ++++ EG+ +
Sbjct: 487 EFRMKFHKPVVIDMFCYRRFGHNEGDEPAFTQPKMYKAIRAHKTVVQLYSDRLIAEGLIS 546
Query: 1425 EQYVKEELTKYGSILEDAYENAQKVTYVRNR-DWLDSPWDDF--FKKRDPLKLPSTGXXX 1255
E V++ + + LE +E Q +Y N+ DWLD W +D + T
Sbjct: 547 EGEVEKMKADWRAHLEQEFEAGQ--SYKPNKADWLDGAWSGLRTADNQDEQRRGRTSVPM 604
Query: 1254 XXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHV 1078
K S+ P GF+ HR ++R ++ R M++ +DWA EALAFG+L+ EG +
Sbjct: 605 KQLKEVGRKLSEIPAGFSAHRTIQRFMENRANMIQTGEGIDWAMAEALAFGTLVTEGTKI 664
Query: 1077 RLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELG 898
RLSGQD +RGTFS RH VL+DQ+ +++ Y PL +LS Q Y V NS LSE AVLGFE G
Sbjct: 665 RLSGQDCERGTFSQRHSVLYDQETEER-YIPLANLSPTQARYEVINSMLSEEAVLGFEYG 723
Query: 897 YSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHS 718
YS+ PN+L +WEAQFGDF+N AQ + DQFISSG+ KW+R SGLV LLPHGYEG GPEHS
Sbjct: 724 YSLARPNALTLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGYEGQGPEHS 783
Query: 717 SARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMP 538
SAR ERFLQ+C ED N VAN TTPAN +H+LRRQV
Sbjct: 784 SARLERFLQLCAED----------------------NMQVANVTTPANYFHILRRQVKRD 821
Query: 537 FRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQR-------VIPETGAPSQNPPDVKRVV 379
FRKP ++ +PKSLLRH A S + + S+F R VI + Q ++RVV
Sbjct: 822 FRKPLILMTPKSLLRHKRAVSSLSEMAGESSFHRLLWDDAEVIKDGPIKLQKDSKIRRVV 881
Query: 378 FCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKN 199
C+GKVYYD++ R+ G + D+ L+RVEQL PFP + E +++ AE++W QEE KN
Sbjct: 882 MCSGKVYYDLLEEREKRGID-DIYLLRVEQLYPFPAKALINELSRFRNAEMVWCQEEPKN 940
Query: 198 MGAWSFVQPRINSLLS-IDGR--ATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFG 37
MGAWSF+ P + +L+ ID + +Y GR ++SPATG H+ + + G
Sbjct: 941 MGAWSFIDPYLEWVLAHIDAKYQRVRYTGRPAAASPATGLMSKHLAQLAAFLEDALG 997
>gi|13473636|ref|NP_105204.1| alpha-ketoglutarate dehydrogenase
[Mesorhizobium loti MAFF303099]
gi|14024386|dbj|BAB50990.1| alpha-ketoglutarate dehydrogenase
[Mesorhizobium loti]
Length = 995
Score = 732 bits (1889), Expect = 0.0
Identities = 419/1013 (41%), Positives = 586/1013 (57%), Gaps = 45/1013 (4%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYF-----------RNVEXXXXXXXXXXXXX 2794
FL G ++ YI+ +Y A+ DP+SV+ W +F RN +
Sbjct: 16 FLYGGNADYIDALYAAYEDDPASVNPEWQEFFAGLKDDAGDVRRNAKGASWAKPSWPLQA 75
Query: 2793 XXAYAGALGVSPAAAQVTTSSAPATRLDTNASV-------QSISDHLKIQLLIRSYQTRG 2635
AL + + + TN V Q+ D ++ ++IR+Y+ RG
Sbjct: 76 NGELVSALDGNWGIVEKHLEKKVKDKAVTNGVVLSDADVHQATRDSVRAIMMIRAYRMRG 135
Query: 2634 HNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREIL 2455
H A+LDPLGI + L+D EL YG D DR L + + T+R++L
Sbjct: 136 HLHANLDPLGI-AKPLEDY--NELSPENYGFTAADYDRPIFLDNVLGL---EFGTIRQML 189
Query: 2454 QRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFE-APRVTELSHDQKKVLFKRLIRSTKFEE 2278
+ L YC++ GVE+MH+++ E++ WI+ R E A + ++ KK + ++L+ + FE+
Sbjct: 190 EILTRTYCSTLGVEFMHISDPEEKAWIQARIEGADKEISFTNTGKKAILQKLVEAEGFEQ 249
Query: 2277 FLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPL 2098
F+ K+ KRFGL+G E LIPA++Q++ LG+ V+GM HRGRLNVL+ V +P
Sbjct: 250 FIDVKYKGTKRFGLDGGEALIPALEQIVKRGGQLGMKEIVLGMAHRGRLNVLSQVMAKPH 309
Query: 2097 ATILSQF---STLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVV 1927
I +F S EGSGDVKYHLG +R V +++ ANPSHLE VDPVV
Sbjct: 310 RAIFHEFKGGSAAPDEVEGSGDVKYHLGASSDR--EFDGNKVHLSLTANPSHLEIVDPVV 367
Query: 1926 MGKVRAEAFYAGD---------EKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTH 1774
MGK RA+ Y E+ + + +LLHGDAAFAGQGV+ E L L +
Sbjct: 368 MGKARAKQDYLFGRGREEIVPLEERAKVLPLLLHGDAAFAGQGVIAEILGLSGLRGHRVA 427
Query: 1773 GAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRK 1594
G +H ++NNQIGFTT+PR SRSSPY +DV +++ PIFHVN DDPEAV+H VA ++R
Sbjct: 428 GTLHFIINNQIGFTTNPRFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVHATKVAIEFRM 487
Query: 1593 TFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYV 1414
F K V+VD+ CYRR GHNE DEP FTQP+MY+ I+ KT ++ Y ++++ EG + +
Sbjct: 488 KFHKPVVVDMFCYRRFGHNEGDEPAFTQPIMYRNIRTHKTTVQIYADRLIAEGHITQAEL 547
Query: 1413 KEELTKYGSILEDAYENAQKVTYVRNR-DWLDSPWDDF--FKKRDPLKLPSTGXXXXXXX 1243
+ + + LE +E Q Y N+ DWLD W +D + T
Sbjct: 548 DQMKADWRAHLESEWEVGQH--YKPNKADWLDGAWSGLRTADNQDEQRRGKTAVPVKTLK 605
Query: 1242 XXIGKFSQYPEGFNLHRGLERTLKGRQQMLKD-NSLDWACGEALAFGSLLKEGIHVRLSG 1066
K ++ P+GF H+ + R L+ R++ ++ +DW+ EALAFG++L +G +RLSG
Sbjct: 606 EIGKKLTEVPKGFEAHKTIIRFLENRREAIESGEGIDWSTAEALAFGAILLDGNPIRLSG 665
Query: 1065 QDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMV 886
QD +RGTFS RH VL+DQ+ D+ Y PLN+LS Q Y V NS LSE AVLGFE GYS+
Sbjct: 666 QDSERGTFSQRHSVLYDQR-DETRYIPLNNLSAAQAGYEVINSMLSEEAVLGFEYGYSLA 724
Query: 885 DPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARP 706
+P +L +WEAQFGDF+N AQ + DQFISSG+ KW+R SGLV LLPHGYEG GPEHSSAR
Sbjct: 725 EPKALTLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGYEGQGPEHSSARL 784
Query: 705 ERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKP 526
ERFLQ+C ED N VANCTTPAN +H+LRRQ+ FRKP
Sbjct: 785 ERFLQLCAED----------------------NMQVANCTTPANYFHILRRQLKRDFRKP 822
Query: 525 AVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPP-------DVKRVVFCTG 367
++ +PKSLLRH A S + + S+F R++ + N P ++RVV C+G
Sbjct: 823 LILMTPKSLLRHKRAVSTLPEISGESSFHRLLWDDAQLLPNQPIKLTKDSKIRRVVLCSG 882
Query: 366 KVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAW 187
KVYYD+ R+ G ND+ L+RVEQL PFP + E +++ AE++W QEE KNMGAW
Sbjct: 883 KVYYDLYEEREKRG-INDIYLLRVEQLYPFPAKALITELSRFRNAEMVWCQEEPKNMGAW 941
Query: 186 SFVQPRINSLLS-IDGR--ATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFG 37
SF+ P + +L+ ID + +Y GR ++SPATG H+ + ++ G
Sbjct: 942 SFIDPYLEWVLAHIDAKHQRVRYTGRPAAASPATGLMSKHLAQLAALLEDALG 994
>gi|49474814|ref|YP_032856.1| Alpha-ketoglutarate dehydrogenase
[Bartonella quintana]
gi|49240318|emb|CAF26800.1| Alpha-ketoglutarate dehydrogenase
[Bartonella quintana str. Toulouse]
Length = 999
Score = 726 bits (1875), Expect = 0.0
Identities = 416/1023 (40%), Positives = 589/1023 (56%), Gaps = 52/1023 (5%)
Frame = -1
Query: 2979 RNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXX 2800
R + + FL G ++ YI+Q+Y + ++P+SV + W A+F ++
Sbjct: 3 RQDEINSLFAQTSFLYGGNANYIDQLYAEYEKNPTSVDSQWRAFFETLQDNKEDVLKNAQ 62
Query: 2799 XXX-------------------------XAYAGALGVSPAAAQVTTSSAPATRLDTNASV 2695
+ G A VT +++ D +
Sbjct: 63 GATWRREHWPLKENGELVSALDGDWFALEKHLGGKLKEKIATGVTQKGKTSSKQDI---I 119
Query: 2694 QSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREF 2515
Q+ D + ++I +++ RGH A LDPL + + L+D EL YG D +R
Sbjct: 120 QATRDSVHALMMIHAFRARGHLHARLDPLQL-AEKLEDY--KELSPEAYGFTSADYERPI 176
Query: 2514 LLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAP--RVTE 2341
+ + + T+ ++L+ L YC++ GVEYMH+++ Q+ W++ R E P R++
Sbjct: 177 FIDNVLGL---EYATIPQMLEILNRTYCSTIGVEYMHISDPAQKTWLQERIEGPDNRIS- 232
Query: 2340 LSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSF 2161
+ +KK + +LI + FE+FL K+ KRFG++G E LIPA++Q+I STLGV
Sbjct: 233 FTPKEKKAILNKLIEAEGFEQFLDIKYKGTKRFGIDGGEALIPALEQIIKYGSTLGVQEV 292
Query: 2160 VIGMPHRGRLNVLANVCRQPLATILSQFS--TLEPAD-EGSGDVKYHLGVCIERLNRQSQ 1990
V+GM HRGRLNVL+ V +P I +F + +P D EGSGDVKYHLG +
Sbjct: 293 VLGMAHRGRLNVLSQVLAKPHQAIFHEFKGGSYKPDDVEGSGDVKYHLGTSADL--EFDG 350
Query: 1989 KNVKIAVVANPSHLEAVDPVVMGKVRAEAFY-AGDEKCD--------RTMAILLHGDAAF 1837
K + ++++ANPSHLE V+PVV+GK RA+ G + + + + +L+HGDAAF
Sbjct: 351 KKLHLSLLANPSHLEIVNPVVIGKTRAKQDQLVGTVRTEVISLSERAKVLPLLIHGDAAF 410
Query: 1836 AGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFH 1657
AGQGV+ ETF L L Y G+IH++VNNQIGFTTDPR SRSSPY +DV +++ PIFH
Sbjct: 411 AGQGVIQETFGLSGLKGYRVAGSIHVIVNNQIGFTTDPRFSRSSPYPSDVAKMIDAPIFH 470
Query: 1656 VNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTK 1477
VN DDPEAV+ + +A ++R+ F K V++D+ CYRR+GHNE DEP FTQPLMY+ I+ K
Sbjct: 471 VNGDDPEAVVFIAKIATEFRQIFHKPVVIDMFCYRRYGHNEGDEPSFTQPLMYKAIRNHK 530
Query: 1476 TALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDF-- 1303
T L+ Y ++++ EGV + + ++++ + LE +E A DWLD W
Sbjct: 531 TTLQLYGDQLVKEGVISLEEIEQQKKLWRDKLEAEFE-ASTSYKPSKADWLDGSWTGLKA 589
Query: 1302 FKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLK-DNSLDWAC 1126
+ +TG K + P F++H+ ++R L R ++ + +DWA
Sbjct: 590 SSNTEEQYFGTTGVALKTLKEIGQKLVEIPPNFHVHKTIQRFLSNRAKVFETGEGVDWAT 649
Query: 1125 GEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTV 946
EALAFGSL EG VRLSG+DV+RGTFS RH VL+DQ+ + + Y PLN+L +GQG Y V
Sbjct: 650 AEALAFGSLCLEGASVRLSGEDVERGTFSQRHSVLYDQENEAR-YIPLNNLQKGQGIYEV 708
Query: 945 CNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGL 766
NS LSE AVLGFE GYS+ +P+ L +WEAQFGDFSN AQ I DQFISS + KW+R SGL
Sbjct: 709 VNSMLSEEAVLGFEYGYSLAEPHGLTLWEAQFGDFSNGAQVIFDQFISSAERKWLRMSGL 768
Query: 765 VMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCT 586
V LLPHG+EG GPEHSSAR ERFLQ+C ED N VANCT
Sbjct: 769 VCLLPHGFEGQGPEHSSARLERFLQLCAED----------------------NMQVANCT 806
Query: 585 TPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQR-------VIP 427
TPAN +H+LRRQ+ FRKP ++ +PKSLLRH A S + + F R ++
Sbjct: 807 TPANYFHILRRQIKRDFRKPLILMTPKSLLRHKRAVSFLNEMGPEKRFHRLLLDGAELLK 866
Query: 426 ETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECR 247
+ Q ++R+V CTGKVYYD+ R+ G NDV L+R+EQL PFP +
Sbjct: 867 NSVVKLQKDNKIRRIVLCTGKVYYDLYEEREKRG-INDVYLLRIEQLYPFPAKALVDVLS 925
Query: 246 KYQGAEILWAQEEHKNMGAWSFVQPRINSLL---SIDGRATKYAGRLPSSSPATGNKFTH 76
++ AEI+W QEE KNMGAWSF++P + +L + +Y GR S+SPATG H
Sbjct: 926 RFLQAEIVWCQEEPKNMGAWSFIEPYLEWVLTHINAQYSRARYVGRPASASPATGLMVKH 985
Query: 75 MQE 67
+++
Sbjct: 986 LEQ 988
>gi|23502773|ref|NP_698900.1| 2-oxoglutarate dehydrogenase, E1
component [Brucella suis 1330]
gi|23348793|gb|AAN30815.1| 2-oxoglutarate dehydrogenase, E1 component
[Brucella suis 1330]
Length = 1004
Score = 725 bits (1872), Expect = 0.0
Identities = 423/1019 (41%), Positives = 582/1019 (56%), Gaps = 51/1019 (5%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYF-----------RNVEXXXXXXXXXXXXX 2794
FL G ++ YIE++Y + DP+SV W +F +N E
Sbjct: 20 FLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGPSWTRKNWPIAA 79
Query: 2793 XXAYAGALGVSPA-------------AAQVTTSSAPATRLDTNASVQSISDHLKIQLLIR 2653
AL + A AA+ A T L Q+ D ++ ++IR
Sbjct: 80 NGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAARDSVRAIMMIR 139
Query: 2652 SYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSL 2473
+Y+ RGH A+LDPLG+ D ELE YG D +R+ + + +
Sbjct: 140 AYRMRGHLHANLDPLGLAEKPNDYN---ELEPENYGFTPADYNRKIFIDNVLGL---EYA 193
Query: 2472 TLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAP-RVTELSHDQKKVLFKRLIR 2296
T+ E+L LK YC + GVE+MH+++ ++ WI+ R E P + + + KK + +LI
Sbjct: 194 TVPEMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKLIE 253
Query: 2295 STKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLAN 2116
+ FE+F+ K+ KRFGL+G E LIPA++Q++ +G+ V+GM HRGRLNVL+
Sbjct: 254 AEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVLSQ 313
Query: 2115 VCRQPLATILSQFS--TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLE 1945
V +P I +F + P D EGSGDVKYHLG +R V +++ ANPSHLE
Sbjct: 314 VMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDR--EFDGNKVHLSLTANPSHLE 371
Query: 1944 AVDPVVMGKVRAEA-FYAGDEKCD--------RTMAILLHGDAAFAGQGVVLETFNLDDL 1792
V+PVVMGK RA+ G + D + + +LLHGDAAFAGQGVV E L L
Sbjct: 372 IVNPVVMGKARAKQDLLVGRTRDDMVPLSERAKVLPLLLHGDAAFAGQGVVAECLGLSGL 431
Query: 1791 PSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNV 1612
+ G +H ++NNQIGFTT+P SRSSPY +DV +++ PIFHVN DDPEAV+ V
Sbjct: 432 KGHRVAGTLHFIINNQIGFTTNPAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAKV 491
Query: 1611 AADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGV 1432
A ++R TF K V++D+ CYRR GHNE DEP FTQPLMY+ I+ KT ++ Y EK++ EG+
Sbjct: 492 ATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEGL 551
Query: 1431 ANEQYVKEELTKYGSILEDAYENAQKVTYVRNR-DWLDSPWDDF--FKKRDPLKLPSTGX 1261
+ + + LE +E Q +Y N+ DWLD W D + T
Sbjct: 552 VTQDDIDRMKADWRQKLEGEFEAGQ--SYKPNKADWLDGAWAGLRTADNADEQRRGKTAV 609
Query: 1260 XXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGI 1084
K + P+ F++HR ++R L R +M++ +DWA E+LAFGSL EG
Sbjct: 610 PVKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGEGIDWATAESLAFGSLAVEGH 669
Query: 1083 HVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFE 904
+RLSGQDV+RGTFS RH VL+DQ+ +Q Y PLN+L +GQ Y NS LSE AVLG+E
Sbjct: 670 PIRLSGQDVERGTFSQRHTVLYDQE-NQNRYIPLNNLQKGQAIYEAINSMLSEEAVLGYE 728
Query: 903 LGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPE 724
GYS+ DP +LV+WEAQFGDF+N AQ + DQFISSG+ KW+R SGLV LLPHG+EG GPE
Sbjct: 729 YGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGFEGQGPE 788
Query: 723 HSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVT 544
HSSAR ER+LQ+C ED N VAN TTPAN +H+LRRQ+
Sbjct: 789 HSSARLERYLQLCAED----------------------NMQVANVTTPANYFHILRRQMK 826
Query: 543 MPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVI-------PETGAPSQNPPDVKR 385
FRKP ++ +PKSLLRH A S + + S+F R++ + G Q ++R
Sbjct: 827 RDFRKPLIMMTPKSLLRHKRAISTLAELSGESSFHRLLWDDAQYNKDEGIKLQKDAKIRR 886
Query: 384 VVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEH 205
VV C+GKVYYD+ R+ G + DV L+RVEQL PFP + E +++ AE++W QEE
Sbjct: 887 VVLCSGKVYYDLYEEREKRGID-DVYLLRVEQLYPFPAKALINELSRFRHAEMVWCQEEP 945
Query: 204 KNMGAWSFVQPRINSLLS-IDGR--ATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFG 37
KNMGAWSF+ P + +L+ ID + +YAGR ++SPATG H+ + + G
Sbjct: 946 KNMGAWSFIDPYLEWVLAHIDAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDALG 1004
>gi|17986424|ref|NP_539058.1| 2-OXOGLUTARATE DEHYDROGENASE E1
COMPONENT [Brucella melitensis 16M]
gi|25284477|pir||AG3269 oxoglutarate dehydrogenase (lipoamide) (EC
1.2.4.2) [imported] - Brucella melitensis (strain 16M)
gi|17982019|gb|AAL51322.1| 2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT
[Brucella melitensis 16M]
Length = 1004
Score = 723 bits (1866), Expect = 0.0
Identities = 422/1019 (41%), Positives = 581/1019 (56%), Gaps = 51/1019 (5%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYF-----------RNVEXXXXXXXXXXXXX 2794
FL G ++ YIE++Y + DP+SV W +F +N E
Sbjct: 20 FLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGPSWTRKNWPIAA 79
Query: 2793 XXAYAGALGVSPA-------------AAQVTTSSAPATRLDTNASVQSISDHLKIQLLIR 2653
AL + A AA+ A T L Q+ D ++ ++IR
Sbjct: 80 NGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAARDSVRAIMMIR 139
Query: 2652 SYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSL 2473
+Y+ RGH A+LDPLG+ D ELE YG D +R+ + + +
Sbjct: 140 AYRMRGHLHANLDPLGLAEKPNDYN---ELEPENYGFTPADYNRKIFIDNVLGL---EYA 193
Query: 2472 TLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAP-RVTELSHDQKKVLFKRLIR 2296
T+ E+L LK YC + GVE+MH+++ ++ WI+ R E P + + + KK + +LI
Sbjct: 194 TVPEMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKLIE 253
Query: 2295 STKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLAN 2116
+ FE+F+ K+ KRFGL+G E LIPA++Q++ +G+ V+GM HRGRLNVL+
Sbjct: 254 AEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVLSQ 313
Query: 2115 VCRQPLATILSQFS--TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLE 1945
V +P I +F + P D EGSGDVKYHLG +R V +++ ANPSHLE
Sbjct: 314 VMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDR--EFDGNKVHLSLTANPSHLE 371
Query: 1944 AVDPVVMGKVRAEA-FYAGDEKCD--------RTMAILLHGDAAFAGQGVVLETFNLDDL 1792
V+PVVMGK RA+ G + D + + +LLHGDAAFAGQGVV E L L
Sbjct: 372 IVNPVVMGKARAKQDLLVGRTRDDMVPLSERAKVLPLLLHGDAAFAGQGVVAECLGLSGL 431
Query: 1791 PSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNV 1612
+ G +H ++NNQIGFTT+P SRSSPY +DV +++ PIFHVN DDPEAV+ V
Sbjct: 432 KGHRVAGTLHFIINNQIGFTTNPAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAKV 491
Query: 1611 AADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGV 1432
A ++R TF K V++D+ CYRR GHNE DEP FTQPLMY+ I+ KT ++ Y EK++ EG+
Sbjct: 492 ATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEGL 551
Query: 1431 ANEQYVKEELTKYGSILEDAYENAQKVTYVRNR-DWLDSPWDDF--FKKRDPLKLPSTGX 1261
+ + + LE +E Q +Y N+ DWLD W D + T
Sbjct: 552 VTQDDIDRMKADWRQKLEGEFEAGQ--SYKPNKADWLDGAWAGLRTADNADEQRRGKTAV 609
Query: 1260 XXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGI 1084
K + P+ F++HR ++R L R +M++ +DWA E+LAFGSL E
Sbjct: 610 PVKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGEGIDWATAESLAFGSLAVEAH 669
Query: 1083 HVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFE 904
+RLSGQDV+RGTFS RH VL+DQ+ +Q Y PLN+L +GQ Y NS LSE AVLG+E
Sbjct: 670 PIRLSGQDVERGTFSQRHTVLYDQE-NQNRYIPLNNLQKGQAIYEAINSMLSEEAVLGYE 728
Query: 903 LGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPE 724
GYS+ DP +LV+WEAQFGDF+N AQ + DQFISSG+ KW+R SGLV LLPHG+EG GPE
Sbjct: 729 YGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGFEGQGPE 788
Query: 723 HSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVT 544
HSSAR ER+LQ+C ED N VAN TTPAN +H+LRRQ+
Sbjct: 789 HSSARLERYLQLCAED----------------------NMQVANVTTPANYFHILRRQMK 826
Query: 543 MPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVI-------PETGAPSQNPPDVKR 385
FRKP ++ +PKSLLRH A S + + S+F R++ + G Q ++R
Sbjct: 827 RDFRKPLIMMTPKSLLRHKRAISTLAELSGESSFHRLLWDDAQYNKDEGIKLQKDAKIRR 886
Query: 384 VVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEH 205
VV C+GKVYYD+ R+ G + DV L+RVEQL PFP + E +++ AE++W QEE
Sbjct: 887 VVLCSGKVYYDLYEEREKRGID-DVYLLRVEQLYPFPAKALINELSRFRHAEMVWCQEEP 945
Query: 204 KNMGAWSFVQPRINSLLS-IDGR--ATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFG 37
KNMGAWSF+ P + +L+ ID + +YAGR ++SPATG H+ + + G
Sbjct: 946 KNMGAWSFIDPYLEWVLAHIDAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDALG 1004
>gi|49476303|ref|YP_034344.1| Alpha-ketoglutarate dehydrogenase
[Bartonella henselae str. Houston-1]
gi|49239111|emb|CAF28415.1| Alpha-ketoglutarate dehydrogenase
[Bartonella henselae str. Houston-1]
Length = 999
Score = 723 bits (1866), Expect = 0.0
Identities = 419/1030 (40%), Positives = 588/1030 (56%), Gaps = 49/1030 (4%)
Frame = -1
Query: 2979 RNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXX 2800
R + + FL G ++ YI+Q+Y + +DP+SV + W +F N++
Sbjct: 3 RQDEINSLFAQTSFLYGGNADYIDQLYADYEKDPTSVDSQWRTFFENLQDKKEDVLKNAQ 62
Query: 2799 XXX-----------XAYAGAL-GVSPAAAQ---------VTTSSAPATRLDTNASV-QSI 2686
AL G P + T + R+ + + ++
Sbjct: 63 GATWQRDHWPLKANGELVSALDGDWPVLEKHVGDKLKEKAATGAVQKGRISSEQDIIRAT 122
Query: 2685 SDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLP 2506
D + ++IR+++ RGH A LDPL + + ++D EL YG D +R +
Sbjct: 123 RDSIHALMMIRAFRARGHLRAKLDPLQL-AEKIEDY--KELSPEAYGFTPADYERPIFID 179
Query: 2505 PTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRV-TELSHD 2329
+ + T+ ++L+ L YC++ G+EYMH+++ Q+ W++ R E P +
Sbjct: 180 NVLGL---EYATIPQMLEILNRTYCSTIGIEYMHISDPVQKAWLQERIEGPNNHIAFTQK 236
Query: 2328 QKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGM 2149
KK + +LI + FE+FL K+ KRFG++G E LIPA+K++I S+LGV V+GM
Sbjct: 237 GKKEILNKLIEAEGFEQFLDTKYKGTKRFGIDGGEALIPALKEIIKCGSSLGVQEVVLGM 296
Query: 2148 PHRGRLNVLANVCRQPLATILSQFS--TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVK 1978
HRGRLNVL+ V +P I +F + +P D EGSGDVKYHLG + K V
Sbjct: 297 AHRGRLNVLSQVLAKPHRAIFHEFKGGSYKPDDVEGSGDVKYHLGTSADL--EFDGKKVH 354
Query: 1977 IAVVANPSHLEAVDPVVMGKVRAEAFYA-GDEKCD--------RTMAILLHGDAAFAGQG 1825
++++ANPSHLE VDPVV+GK RA+ G + D + + +L+HGDAAFAGQG
Sbjct: 355 LSLLANPSHLEIVDPVVIGKARAKQDQLIGPTRTDTLPLSERSKVLPLLIHGDAAFAGQG 414
Query: 1824 VVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVD 1645
V+ ETF L L Y G+IH ++NNQIGFTT+PR SRSSPY +DV +++ PIFHVN D
Sbjct: 415 VIQETFGLSGLKGYRVAGSIHFIINNQIGFTTNPRFSRSSPYPSDVAKMIDAPIFHVNGD 474
Query: 1644 DPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALE 1465
DPEAV+ V +A ++R+ F K V++D+ CYRR+GHNE DEP FTQPLMY+ I+ KT L+
Sbjct: 475 DPEAVVFVAKLATEFRQIFHKPVVIDMFCYRRYGHNEGDEPSFTQPLMYKAIRNHKTTLQ 534
Query: 1464 KYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNR-DWLDSPWDDFFKKR- 1291
Y ++++ EGV + ++++ + LE E +Y N+ DWLD W
Sbjct: 535 LYGDQLIEEGVITVEEIEQQKKLWRDKLE--VELEASTSYKPNKADWLDGSWTGLKASNN 592
Query: 1290 -DPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLK-DNSLDWACGEA 1117
D +TG K + P F++H+ ++R L R ++ + +DWA EA
Sbjct: 593 VDEQHSGTTGVDLKTLKEIGEKLVEIPADFHVHKTIQRFLNNRAKIFETGEGVDWATAEA 652
Query: 1116 LAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNS 937
LAFGSL EG VRLSG+DV+RGTFS RH VL+DQ+ + + Y PLN+L +GQ Y V NS
Sbjct: 653 LAFGSLCLEGAPVRLSGEDVERGTFSQRHSVLYDQENEAR-YIPLNNLQKGQALYEVVNS 711
Query: 936 SLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVML 757
LSE AVLGFE GYS+ +P L +WEAQFGDFSN AQ I DQFISS + KW+R SGLV L
Sbjct: 712 MLSEEAVLGFEYGYSLAEPRGLTLWEAQFGDFSNGAQVIFDQFISSAERKWLRMSGLVCL 771
Query: 756 LPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPA 577
LPHG+EG GPEHSSAR ERFLQ+C ED N VANCTTPA
Sbjct: 772 LPHGFEGQGPEHSSARLERFLQLCAED----------------------NMQVANCTTPA 809
Query: 576 NIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQR-------VIPETG 418
N +H+LRRQ+ FRKP ++ +PKSLLRH A S + + + F R V+ +
Sbjct: 810 NYFHILRRQIKRDFRKPLILMTPKSLLRHKRAVSFLNEMGLETRFHRLLLDDAEVLKNSV 869
Query: 417 APSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQ 238
Q ++R+V CTGKVYYD+ R+ G + DV L+RVEQL PFP + ++
Sbjct: 870 VKLQKDNKIRRIVLCTGKVYYDLYEEREKRGID-DVYLLRVEQLYPFPAKALVDVLSRFL 928
Query: 237 GAEILWAQEEHKNMGAWSFVQPRINSLL---SIDGRATKYAGRLPSSSPATGNKFTHMQE 67
AE++W QEE KNMGAWSF++P + +L + +YAGR S+SPATG H ++
Sbjct: 929 QAEVIWCQEEPKNMGAWSFIEPYLEWVLTHINAQYSRARYAGRPASASPATGLMVQHAEQ 988
Query: 66 QKEMMSKVFG 37
+ G
Sbjct: 989 LAAFLEDALG 998
>gi|50404917|ref|YP_054009.1| 2-oxoglutarate dehydrogenase, putative
[Paramecium tetraurelia]
gi|50057294|emb|CAH03278.1| 2-oxoglutarate dehydrogenase, putative
[Paramecium tetraurelia]
Length = 964
Score = 714 bits (1842), Expect = 0.0
Identities = 399/996 (40%), Positives = 578/996 (57%), Gaps = 34/996 (3%)
Frame = -1
Query: 2925 SSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAAAQ 2746
S+ Y+ ++E W ++P SV W YF G GV Q
Sbjct: 14 SATYVSGLFEHWQKNPQSVPEGWRQYF-----------------SEQINGGAGV-----Q 51
Query: 2745 VTTSSAPATRLDTNASVQSISDHLK-IQLLIRSYQ------TRGHNIADLDPLGINSADL 2587
TTS P DH K IQLL R+Y GH +ADLDPL + +
Sbjct: 52 GTTSLNPL-------------DHAKQIQLLYRTYYMFRMFFVCGHQLADLDPLNLPNTKE 98
Query: 2586 DDTIP---PELELSFYGLGERDLD----------REFLLPPTTFISEKKSLTLREILQRL 2446
+ PE+ L +G + +LD R F+ P F+ K+ T+REI RL
Sbjct: 99 YGRVKGSRPEMTLDSFGFKKEELDIPIYFGNKDQRSFIYP---FMEVKEEWTIREIYDRL 155
Query: 2445 KDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAK 2266
IY GVEY+H+ + EQ+ W+ + + + S + + ++RL R F EFL
Sbjct: 156 SQIYTKKYGVEYIHMVSTEQKHWVEQEMDRIAQWKPSKETQTATWQRLARVDLFNEFLKN 215
Query: 2265 KWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATIL 2086
++ + KRFG+EG + LI ++ ++D + V+ ++GM HRGRL+ LANV ++PL I
Sbjct: 216 RFTTSKRFGIEGTDTLIVGLEALVDQCAQNKVEHIIVGMAHRGRLSTLANVFKKPLEIIF 275
Query: 2085 SQFST-----LEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMG 1921
++F +E + GDVKYHLGV ++ ++++ ++ NPSHLEAV+PVV G
Sbjct: 276 AEFQNKYSKEIEESWGNIGDVKYHLGVTRDQ-QFPDGHHIRMTMLPNPSHLEAVNPVVQG 334
Query: 1920 KVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQI 1741
K RA G+++ + I++HGDAA AGQGVV E+ L++L Y+ G IH+VVNNQI
Sbjct: 335 KTRALQDICGNKQ--NCLGIIIHGDAAMAGQGVVYESLQLENLTGYSNEGVIHVVVNNQI 392
Query: 1740 GFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLV 1561
GFTT P SRS YCTDV + + PI HVN DDP+ V + +A +R+ FKKD+++DL+
Sbjct: 393 GFTTTPIDSRSGLYCTDVAKAIDVPIIHVNADDPDLVEEIFKIAVRFRQQFKKDIVIDLI 452
Query: 1560 CYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSIL 1381
YRR+GHNE D+P FTQP MY+ I + K + Y +++ GV + + E+ K + L
Sbjct: 453 GYRRYGHNEQDQPAFTQPQMYEIINKQKPVFQLYDQQLRKNGVITDDFASTEIKKLNNSL 512
Query: 1380 EDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFN 1201
E AY+N QK T+ + W+ PW+ + K+ TG K + P
Sbjct: 513 ETAYKNIQKETFDKVH-WVPKPWEKIQQVTKWGKVKDTGVALKDLLELNEKVNHLPAELT 571
Query: 1200 LHRGLERTLKGRQQMLKD-NSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHV 1024
+H ++R + R+Q ++ +D+ EALAFG+LL EG +RLSGQD +RGTFS RH V
Sbjct: 572 VHPQVKRIYEQRKQSIEQGKGIDFGTAEALAFGTLLHEGFSIRLSGQDCERGTFSQRHAV 631
Query: 1023 LHDQKVDQKIYNPLNDL-SEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFG 847
L+DQK D K Y N + S G + V NS LSEY VLGFE GYS +PN L IWE QFG
Sbjct: 632 LNDQKKDIKYYPLRNQIPSGGNNRFEVYNSPLSEYGVLGFEYGYSQSNPNVLTIWEGQFG 691
Query: 846 DFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI 667
DF+N Q +ID FI+SG+SKW SGLVM+LPHG +G GPEHSS R ERFLQ+ ++D I
Sbjct: 692 DFANGCQIMIDNFITSGESKWNVPSGLVMMLPHGLDGQGPEHSSGRMERFLQLMDDDPNI 751
Query: 666 DLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHP 487
+ + +Q+ D+N+ V C+ P+N +H LRRQ+ FRKP ++F+ K LL+
Sbjct: 752 VFQ---MKEQRIKRQILDSNFQVCVCSNPSNYFHSLRRQLRRDFRKPLILFNSKRLLKFS 808
Query: 486 MARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVA 307
A S + F G+ F R+IP+T + P ++K+VV C G+VYYD++ R+ K NDVA
Sbjct: 809 KATSDISLFLEGTRFHRLIPDTHEEIKAPKEIKKVVICYGQVYYDILQKRQET-KRNDVA 867
Query: 306 LVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATK- 130
+VRVEQL+PFPYD + ++Y+ AE ++ QEEH+N GAW +++PRI ++LS+ + +K
Sbjct: 868 IVRVEQLAPFPYDHFRVVAQQYENAEFVFCQEEHQNSGAWQYLEPRIQNVLSLLHQQSKI 927
Query: 129 ------YAGRLPSSSPATGNKFTHMQEQKEMMSKVF 40
+ GR PS+S A+G+ H QE ++++S +F
Sbjct: 928 KHQYLTFCGRRPSASTASGSPTVHKQELEKLLSILF 963
>gi|48851310|ref|ZP_00305552.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Novosphingobium aromaticivorans DSM 12444]
Length = 951
Score = 706 bits (1821), Expect = 0.0
Identities = 400/914 (43%), Positives = 544/914 (58%), Gaps = 20/914 (2%)
Frame = -1
Query: 2715 LDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGE 2536
LD A Q+ D ++ LIR+Y+ RGH ADLDPLG+ L + PE +YG
Sbjct: 64 LDEAALQQAAMDAIRAMTLIRTYRVRGHLAADLDPLGLARQKLPADLSPE----YYGFTA 119
Query: 2535 RDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEA 2356
D+ R+ L + + T+ E++ L+ YC G EYMH++++E++ +I+ R E
Sbjct: 120 ADMTRKVYLGGALGL---EWATVNELVAILRANYCGHVGFEYMHISDVEERRFIQDRIEG 176
Query: 2355 -PRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSST 2179
+ + + + KK + ++R ++E+FL KK+ KRFGL+G E +IPA++ +I
Sbjct: 177 GDKSIDFTPNGKKAILAAVVRGEQYEKFLGKKYVGTKRFGLDGGESMIPALEALIKYGGQ 236
Query: 2178 LGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS--TLEPADEG-SGDVKYHLGVCIER 2008
LGV V GM HRGRLNVLANV +P I +FS + P D G SGDVKYHLG +R
Sbjct: 237 LGVREIVYGMAHRGRLNVLANVMAKPYRVIFHEFSGGSANPEDVGGSGDVKYHLGTSTDR 296
Query: 2007 LNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCD--------RTMAILLH 1852
V +++V NPSHLE VDPVV+GKVRA+ + D D + + +L+H
Sbjct: 297 --EFDGIKVHMSLVPNPSHLETVDPVVLGKVRAQQVFRDDIGDDVGPDARHKQVLPVLIH 354
Query: 1851 GDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVG 1672
GDAAFAGQG+V E F L + Y T G IH ++NNQIGFTT P+ SR SPY +DV + V
Sbjct: 355 GDAAFAGQGIVWECFGLSGVKGYNTGGCIHFIINNQIGFTTSPQFSRGSPYPSDVAKGVQ 414
Query: 1671 CPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQR 1492
PI HVN DDPEAV C +A D+R+ F +D++VD+ CYRR GHNE DEP FTQPLMY +
Sbjct: 415 APIIHVNGDDPEAVTFACKLAIDYRQKFGRDIVVDMWCYRRFGHNEGDEPSFTQPLMYAK 474
Query: 1491 IKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPW 1312
I+Q + Y ++++ EGV + + E + + + LE +E A K DW W
Sbjct: 475 IRQHPGVSDIYAKRLVAEGVIDANHKGEVESHFTATLETEFE-ASKGYKANEADWFGGRW 533
Query: 1311 DDFFKKRDPL---KLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQML-KDN 1144
K DP+ + +TG + PE +H+ L R + +++M
Sbjct: 534 SGLNKPADPVTARRNVATGIDQKMFDSLGRTLTTVPEDLTVHKTLGRVIDAKREMFTSGQ 593
Query: 1143 SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEG 964
DWA GEALAFGSL+ EG VRLSGQD RGTFS RH V DQK D++ Y PL L
Sbjct: 594 GFDWATGEALAFGSLVMEGYGVRLSGQDCGRGTFSQRHAVWVDQK-DERKYVPLTTLP-- 650
Query: 963 QGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKW 784
G + V +S LSEY VLGFE GY+ DP SLV+WE QFGDF+N AQ +IDQ+I++ ++KW
Sbjct: 651 HGSFEVLDSPLSEYGVLGFEYGYASADPKSLVLWEGQFGDFANGAQIVIDQYIAASEAKW 710
Query: 783 IRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNW 604
+R +GLVMLLPHGYEG GPEHSSAR ER+LQ+C ED N
Sbjct: 711 LRANGLVMLLPHGYEGQGPEHSSARLERYLQLCAED----------------------NL 748
Query: 603 IVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPE 424
V N TTPAN +H+LRRQ+ PFRKP ++ +PKSLLRHPMA+S DF +F R++ +
Sbjct: 749 QVCNITTPANYFHVLRRQMHRPFRKPLIIMTPKSLLRHPMAKSVASDFIGEGHFMRILSD 808
Query: 423 TGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYD-LVQQECR 247
T + D +RVV C+GKV YD++ AR + + DV ++R+EQL PFP + L + R
Sbjct: 809 TNGAADK--DTRRVVLCSGKVAYDLIEAR-NAAELADVQVIRLEQLYPFPGEPLALRLSR 865
Query: 246 KYQGAEILWAQEEHKNMGAWSFVQPRI-NSLLSIDGRAT--KYAGRLPSSSPATGNKFTH 76
E++W QEE KN G+W FV+P I SL + + +YAGR S+SPATG H
Sbjct: 866 MPNLEEVVWCQEEPKNNGSWFFVEPLIEESLKAAKSKVARPRYAGRHASASPATGLASRH 925
Query: 75 MQEQKEMMSKVFGV 34
EQ +++ G+
Sbjct: 926 ASEQGALVADALGL 939
>gi|48729504|ref|ZP_00263254.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Pseudomonas fluorescens PfO-1]
Length = 943
Score = 706 bits (1821), Expect = 0.0
Identities = 409/993 (41%), Positives = 567/993 (56%), Gaps = 13/993 (1%)
Frame = -1
Query: 2973 QSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXX 2794
+SV + + +L+G ++ Y+E++YE +L DP++V W YF+ +
Sbjct: 3 ESVMQRMWNSAYLSGGNAAYVEELYELYLHDPNAVPEEWRTYFQKLPADGSSATDVSHST 62
Query: 2793 XXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLD 2614
+ L + AQ ++ + S + +++ LI++Y+ RGH A LD
Sbjct: 63 IRDHFVLLAKNQRRAQPVSAGS--------VSSEHEKKQVEVLRLIQAYRMRGHQAAQLD 114
Query: 2613 PLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIY 2434
PLG+ P +L ++ YGL DLD F FI K+ +LREI + L+ Y
Sbjct: 115 PLGL----WQRPAPADLSINHYGLTNADLDTTFRAGDL-FIG-KEEASLREIHEALQQTY 168
Query: 2433 CTSTGVEYMHLNNLEQQDWIRRRFEAPRVT-ELSHDQKKVLFKRLIRSTKFEEFLAKKWP 2257
C + G E+ H+ + EQ+ W ++R E+ R E S D K L +R+ E++L K+P
Sbjct: 169 CRTIGAEFTHITDSEQRQWFQQRLESVRGRPEYSADIKSHLLERVTAGEGLEKYLGTKYP 228
Query: 2256 SEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQF 2077
KRFGLEG E LIP + ++I S + G VIGM HRGRLNVL N + + +F
Sbjct: 229 GTKRFGLEGGESLIPMLDELIQRSGSYGTKEVVIGMAHRGRLNVLVNTFGKNPRELFDEF 288
Query: 2076 STLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFY 1897
+ + GSGDVKYH G + + V +A+ NPSHLE V PVV G VRA
Sbjct: 289 EGKKKVELGSGDVKYHQGFSSNVMTTGGE--VHLAMAFNPSHLEIVSPVVEGSVRARQDR 346
Query: 1896 AGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFT-TDPR 1720
D ++ + I +HGDAAFAGQGVV+ETF + + T G +HIV+NNQ+GFT ++P
Sbjct: 347 RNDPTGEKVLPISIHGDAAFAGQGVVMETFQMSQTRGFKTGGTVHIVINNQVGFTISNPL 406
Query: 1719 SSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGH 1540
SRS+ Y TDV +++ PI HVN DDPEAV+ V +A D+R FK+DV++DLVCYRR GH
Sbjct: 407 DSRSTEYATDVAKMIQAPILHVNGDDPEAVLFVTQLAIDYRMQFKRDVVIDLVCYRRRGH 466
Query: 1539 NELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAY--- 1369
NE DEP TQPLMYQ+I + +T E Y +++ GV + + V+ ++ +Y + L++
Sbjct: 467 NEADEPSGTQPLMYQQITKQRTTRELYADRLTQAGVLDAERVQAKVDEYRNALDNGLHVV 526
Query: 1368 ----ENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFN 1201
+ K +V R +L W R LK K + PEGF
Sbjct: 527 KSLVKEPNKELFVDWRPYLGHAWTARHDTRFDLK---------TLQELSAKLLEIPEGFV 577
Query: 1200 LHRGLERTLKGRQQMLKDN-SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHV 1024
+ R + + + RQ+M ++W E +A+ +L EG +R++GQD+ RGTFSHRH V
Sbjct: 578 VQRQVAKIYEDRQKMQAGGLPINWGYAETMAYATLAFEGHPIRMTGQDIGRGTFSHRHAV 637
Query: 1023 LHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGD 844
LH+QK D Y PL L EGQ + + +S LSE AVL FE GYS PN+LVIWEAQFGD
Sbjct: 638 LHNQK-DAGTYIPLKHLYEGQPRFDLYDSFLSEEAVLAFEYGYSTTTPNALVIWEAQFGD 696
Query: 843 FSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEID 664
F+N AQ +IDQFI+SG+ KW R GL MLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 697 FANGAQVVIDQFITSGEHKWGRLCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEH---- 752
Query: 663 LEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPM 484
N V TTPA IYHLLRRQV P RKP VV +PKSLLRH +
Sbjct: 753 ------------------NIQVCMPTTPAQIYHLLRRQVIRPLRKPLVVLTPKSLLRHKL 794
Query: 483 ARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVAL 304
A S +ED GS FQ VIPE A +P V+RVV C+GKVYYD++ R+ G+E D+A+
Sbjct: 795 AISTLEDLAEGS-FQTVIPEIDA--LDPKKVERVVLCSGKVYYDLLEKRRAEGRE-DIAI 850
Query: 303 VRVEQLSPFPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLLSIDGRA--T 133
VR+EQL PFP D +++ Y A+ +W QEE N GAW Q + +S ++
Sbjct: 851 VRIEQLYPFPEDDLKEVLAPYTNAKAAVWCQEEPMNQGAWYCSQHHLRRSISNLNKSLVL 910
Query: 132 KYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGV 34
+YAGR S++PA G H ++Q++++ F V
Sbjct: 911 EYAGREASAAPACGYASMHAEQQEQLLQDAFTV 943
>gi|15596782|ref|NP_250276.1| 2-oxoglutarate dehydrogenase (E1
subunit) [Pseudomonas aeruginosa PA01]
gi|11347271|pir||G83448 2-oxoglutarate dehydrogenase (E1 subunit)
PA1585 [imported] - Pseudomonas aeruginosa (strain PAO1)
gi|9947548|gb|AAG04974.1| 2-oxoglutarate dehydrogenase (E1 subunit)
[Pseudomonas aeruginosa PAO1]
Length = 943
Score = 705 bits (1820), Expect = 0.0
Identities = 411/994 (41%), Positives = 564/994 (56%), Gaps = 13/994 (1%)
Frame = -1
Query: 2976 NQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXX 2797
++SV + + L+G ++ Y+E++YE +L DP++V W YF+ +
Sbjct: 2 HESVMQRMWNSAHLSGGNAAYVEELYELYLHDPNAVPEEWRTYFQKLPADGNPAPDVSHS 61
Query: 2796 XXXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADL 2617
+ L + AQ ++ + S + +++ LI +Y+ RGH + L
Sbjct: 62 TVRDHFVLLAKNQRRAQPVSAGS--------VSSEHEKKQVEVLRLIHAYRLRGHQASTL 113
Query: 2616 DPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDI 2437
DPLG+ P +L + YGL DLD F K+ TLREI+ LK
Sbjct: 114 DPLGL----WQRPAPADLSIDHYGLTGADLDTTFRTGELYI--GKEEATLREIVDSLKST 167
Query: 2436 YCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTE-LSHDQKKVLFKRLIRSTKFEEFLAKKW 2260
YC + G E+MH+ + EQ+ W +R E+ R S + + L +RL + E++L K+
Sbjct: 168 YCGTFGAEFMHIVDSEQRKWFLQRLESVRGRPGFSAEARAHLLERLTAAEGLEKYLGTKY 227
Query: 2259 PSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQ 2080
P KRFGLEG E LIP + ++I + G VIGM HRGRLNVL N + + +
Sbjct: 228 PGTKRFGLEGGESLIPMVDEIIQRCGSYGAKEIVIGMAHRGRLNVLVNTLGKNPRDLFDE 287
Query: 2079 FSTLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAF 1900
F + + GSGDVKYH G + S V +A+ NPSHLE V PVV G VRA
Sbjct: 288 FEGKKIVELGSGDVKYHQGFSSNVMT--SGGEVHLALAFNPSHLEIVSPVVEGSVRARQD 345
Query: 1899 YAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPR 1720
D D+ + I +HGDAAFAGQGVV+ETF + +Y T G IH+V+NNQ+GFTT +
Sbjct: 346 RRKDSSGDKVVPISIHGDAAFAGQGVVMETFQMSQTRAYKTGGTIHLVINNQVGFTTSRQ 405
Query: 1719 S-SRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHG 1543
+RS+ Y TDV +++ PIFHVN DDPEAV+ V +A D+R FK+DV++DLVCYRR G
Sbjct: 406 DDARSTEYATDVAKMIQAPIFHVNGDDPEAVLFVTQLAVDYRMQFKRDVVIDLVCYRRRG 465
Query: 1542 HNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAY-- 1369
HNE DEP TQPLMYQ+I + +T E Y + ++N GV + + V+ ++ Y L++
Sbjct: 466 HNEADEPSGTQPLMYQQIAKQRTTRELYADALVNAGVLSAEQVQSKIDDYRDALDNGLHV 525
Query: 1368 -----ENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGF 1204
+ K +V R +L W R LK K + PEGF
Sbjct: 526 VKSLVKEPNKELFVDWRPYLGHAWTARHDTRFDLK---------TLQELSSKMLEVPEGF 576
Query: 1203 NLHRGLERTLKGRQQMLKDN-SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHH 1027
+ R + + + RQ+M ++W E LA+ +LL EG VR++GQDV RGTFSHRH
Sbjct: 577 VVQRQVSKIYEDRQKMAAGGLPINWGFAETLAYATLLFEGHPVRMTGQDVGRGTFSHRHA 636
Query: 1026 VLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFG 847
VLH+QK D +Y PL +L +GQ + +S LSE AVL FE G++ PNSLVIWEAQFG
Sbjct: 637 VLHNQK-DDSVYVPLANLFDGQPRLDIYDSFLSEEAVLAFEYGFATTTPNSLVIWEAQFG 695
Query: 846 DFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI 667
DF+N AQ +IDQFI+SG+SKW R GL MLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 696 DFANGAQVVIDQFITSGESKWGRLCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEQ--- 752
Query: 666 DLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHP 487
N V TTPA +YH+LRRQV P RKP VV +PKSLLRH
Sbjct: 753 -------------------NIQVCVPTTPAQVYHMLRRQVIRPLRKPLVVMTPKSLLRHK 793
Query: 486 MARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVA 307
+A S +ED +GS FQ VIPE S +P V RVV C+GKVYYD++ R+ G+E D A
Sbjct: 794 LAISTLEDLANGS-FQTVIPE--IDSLDPKKVDRVVLCSGKVYYDLLEKRRAEGRE-DTA 849
Query: 306 LVRVEQLSPFPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLLSI--DGRA 136
+VR+EQL PFP D + + Y+ + I+W QEE N GAW Q + +++ G
Sbjct: 850 IVRIEQLYPFPEDDLAEVLAPYKNLKHIVWCQEEPMNQGAWFCSQHHMRRVIAAHKKGLN 909
Query: 135 TKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGV 34
+YAGR S++PA G H ++Q++++ F V
Sbjct: 910 LEYAGREGSAAPACGYASMHAEQQEKLLQDAFTV 943
>gi|23103001|ref|ZP_00089494.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Azotobacter vinelandii]
Length = 943
Score = 705 bits (1819), Expect = 0.0
Identities = 406/989 (41%), Positives = 565/989 (57%), Gaps = 10/989 (1%)
Frame = -1
Query: 2970 SVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXX 2791
SV + + L+G ++ Y+E++YE +L DP++V W YF +
Sbjct: 4 SVMQRMWNSAHLSGGNAAYVEELYELYLHDPNAVPEEWRTYFEKLPAEAGTSTDVPHAPV 63
Query: 2790 XAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDP 2611
L + AQ +S+ +T + +++ LI++Y+TRGH + LDP
Sbjct: 64 RDQFVLLAKNQRRAQPVATSSVSTEHEKK--------QVEVLRLIQAYRTRGHQASQLDP 115
Query: 2610 LGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYC 2431
LG+ T P +L ++ YGL DLD F K+ TLREILQ L++ YC
Sbjct: 116 LGL----WQRTAPSDLSITHYGLTNADLDTPFRTGELYI--GKEEATLREILQALQETYC 169
Query: 2430 TSTGVEYMHLNNLEQQDWIRRRFEAPRVTEL-SHDQKKVLFKRLIRSTKFEEFLAKKWPS 2254
+ G E+ H+ + EQ++W +R E+ R + S + K L +RL + E++L K+P
Sbjct: 170 RTIGAEFTHIVDSEQRNWFAQRLESVRGRPVYSKEAKSHLLERLSAAEGLEKYLGTKYPG 229
Query: 2253 EKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS 2074
KRFGLEG E L+P + ++I S + G VIGM HRGRLN+L N + + +F
Sbjct: 230 TKRFGLEGGESLVPVVDEIIQRSGSYGTKEVVIGMAHRGRLNLLVNALGKNPRDLFDEFE 289
Query: 2073 TLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYA 1894
+ GSGDVKYH G + S V +A+ NPSHLE V PVV G VRA
Sbjct: 290 GKHLVELGSGDVKYHQGFSSNVMT--SGGEVHLAMAFNPSHLEIVSPVVEGSVRARQDRR 347
Query: 1893 GDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRS 1717
D ++ + I +HGD+AFAGQGVV+ETF + + Y T G IHIVVNNQ+GFTT +P
Sbjct: 348 VDATGEKVVPISIHGDSAFAGQGVVMETFQMSQIRGYKTGGTIHIVVNNQVGFTTSNPVD 407
Query: 1716 SRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHN 1537
+RS+ YCTD +++ P+ HVN DDPEAV+ V +A D+R FK+DV++DLVCYRR GHN
Sbjct: 408 TRSTEYCTDPAKMIQAPVLHVNGDDPEAVLFVTQLAVDYRMQFKRDVVIDLVCYRRRGHN 467
Query: 1536 ELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQ 1357
E DEP TQPLMYQ+I + T E Y + ++ EG +++ V+ ++ +Y + L++ +
Sbjct: 468 EADEPSGTQPLMYQKIAKQPTTRELYADALVKEGSLSQEEVQAKVDEYRTALDNGQHVLK 527
Query: 1356 KVTYVRNR----DWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRG 1189
+ N DW + + D T K Q PEGF + R
Sbjct: 528 SLVKEPNTELFVDWTPYLGHAWTARHD------TSFELKTLQELNAKLLQIPEGFVVQRQ 581
Query: 1188 LERTLKGRQQM-LKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQ 1012
+ + L+ R +M + ++W C E LA+ +LLKEG VR++GQDV RGTFSHRH LH+Q
Sbjct: 582 VAKILEDRGRMGVGAMPINWGCAETLAYATLLKEGHPVRITGQDVGRGTFSHRHAALHNQ 641
Query: 1011 KVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNT 832
K D Y PL +L EGQ ++ + +S LSE AVL FE GY+ PN+LVIWEAQFGDF+N
Sbjct: 642 K-DASRYIPLQNLYEGQPKFELYDSFLSEEAVLAFEYGYATTTPNALVIWEAQFGDFANG 700
Query: 831 AQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKI 652
AQ +IDQFISSG++KW R GL MLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 701 AQVVIDQFISSGETKWGRLCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEQ-------- 752
Query: 651 AFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSP 472
N V TTPA +YH+LRRQV P RKP V +PKSLLRH A S
Sbjct: 753 --------------NIQVCVPTTPAQVYHMLRRQVIRPLRKPLVALTPKSLLRHKSAIST 798
Query: 471 VEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVE 292
+ED GS F V+PE S +P V+R+V C+GKVYYD++ R G+E D+A+VR+E
Sbjct: 799 LEDLALGS-FHPVLPE--VDSLDPKKVERLVLCSGKVYYDLLDKRHAEGRE-DIAIVRIE 854
Query: 291 QLSPFPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLLSIDGRA--TKYAG 121
QL PFP + + + Y + ++W QEE N GAW Q + + S + +YAG
Sbjct: 855 QLYPFPEEELAEVMAPYTNLKHVVWCQEEPMNQGAWYCSQHHMRRVASAHKKELFLQYAG 914
Query: 120 RLPSSSPATGNKFTHMQEQKEMMSKVFGV 34
R S++PA G H ++Q++++ F V
Sbjct: 915 REASAAPACGYASMHAEQQEKLLQDAFTV 943
>gi|33597743|ref|NP_885386.1| 2-oxoglutarate dehydrogenase E1
component [Bordetella parapertussis 12822]
gi|33574171|emb|CAE38502.1| 2-oxoglutarate dehydrogenase E1 component
[Bordetella parapertussis]
Length = 957
Score = 701 bits (1809), Expect = 0.0
Identities = 414/1000 (41%), Positives = 578/1000 (57%), Gaps = 23/1000 (2%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L G ++ Y+E++YE++L +P SV +W YF ++
Sbjct: 12 YLFGGNAPYVEELYESYLDNPGSVPDNWREYFDQLQHSPATDGQEATR-----------D 60
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISD--------HLKIQLLIRSYQTRGHNIADLDPLG 2605
A A + S A R NA VQ +++ + +Q LI +Y++ G ADLDPL
Sbjct: 61 QAHAPIVESFAQRAR--ANAFVQRVAEPDLSVASKQVSVQSLIAAYRSLGSRWADLDPLK 118
Query: 2604 INSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTS 2425
+ PEL+ +FYGL E DLD+ + T+ + ++TLR+IL+ L+D YC S
Sbjct: 119 RQ----ERPAIPELDPAFYGLTEADLDQVYSAT-NTYFTTASTMTLRDILKALRDTYCRS 173
Query: 2424 TGVEYMHLNNLEQQDWIRRRFEAP-RVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEK 2248
G E+MH+++ + WI++R E+ S ++K+ + ++L S E FL K+ +K
Sbjct: 174 VGAEFMHISDPAAKRWIQQRLESTFSAPVFSTEEKRHILQQLTESEGLERFLHTKYVGQK 233
Query: 2247 RFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTL 2068
RF LEG E I +M +V++ + GV V+GM HRGRLN+L N+ + + ++F
Sbjct: 234 RFSLEGGESFIASMDEVVNHAGESGVQEIVVGMAHRGRLNLLVNIMGKMPGDLFAEFEGK 293
Query: 2067 EPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGD 1888
GDVKYH G + R ++ +A NPSHLE V+PVV G VRA GD
Sbjct: 294 HAEGLTDGDVKYHNGFSSDLSTRGGPVHLSLAF--NPSHLEIVNPVVEGSVRARQERRGD 351
Query: 1887 EKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSR 1711
+ + + +L+HGDAAFAGQGVV+ET NL Y T G +HIV+NNQIGFTT DPR SR
Sbjct: 352 GEGKQVLPVLVHGDAAFAGQGVVMETLNLAQTRGYGTGGTLHIVINNQIGFTTSDPRDSR 411
Query: 1710 SSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNEL 1531
S+ YCTDV +++ P+FHVN DDPEAV+ +A D+R F+ DV++D+VC+R+ GHNE
Sbjct: 412 STLYCTDVVKMIEAPVFHVNGDDPEAVVFATRLALDYRMQFRHDVVLDIVCFRKLGHNEQ 471
Query: 1530 DEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKV 1351
D P TQPLMY+RI + Y +K+ +GV E + + Y ++ED + V
Sbjct: 472 DTPSLTQPLMYKRIGHHPGTRKLYADKLTTQGVLAEGDADQLVKDYRQLMEDGQRTIEPV 531
Query: 1350 -TYVRNR---DW---LDSPWDDFFKKRDPL-KLPSTGXXXXXXXXXIGKFSQYPEGFNLH 1195
T +++ DW L + W D PL +L G PEGF +H
Sbjct: 532 LTDYKSKYAIDWSPFLGAKWTDQADTAVPLAELKRIGERITTTV---------PEGFTVH 582
Query: 1194 RGLERTLKGRQQMLKDN-SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLH 1018
+ + L R+ M K +LDW GE LAF +L+ G VR++GQD RGTF+HRH VLH
Sbjct: 583 PLVAKLLNDRRNMAKGEVNLDWGMGEHLAFATLVASGYAVRITGQDSGRGTFTHRHAVLH 642
Query: 1017 DQKVDQ---KIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFG 847
DQ ++ Y PL ++SEGQ +TV +S LSE AVL FE GYS V+PN+L IWEAQFG
Sbjct: 643 DQNRERWNDGFYVPLQNVSEGQAPFTVIDSVLSEEAVLAFEYGYSSVEPNTLTIWEAQFG 702
Query: 846 DFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI 667
DF N AQ +IDQFI++G++KW RQSGL ++LPHGYEG GPEHSS R ERFLQ+C
Sbjct: 703 DFVNGAQVVIDQFITAGEAKWGRQSGLTLMLPHGYEGQGPEHSSGRIERFLQLC------ 756
Query: 666 DLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHP 487
D N V T+ A I+HLLRRQ+ PFRKP V+F+PKSLLR+
Sbjct: 757 ----------------ADHNIQVVQPTSAAQIFHLLRRQMIRPFRKPLVIFTPKSLLRNK 800
Query: 486 MARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVA 307
A SP+ D GS F+ VI E S VKRV+ C+GKVYYD+V AR+ G ++ VA
Sbjct: 801 DAGSPLTDLAGGS-FRPVIGEVD-ESIKAASVKRVLACSGKVYYDLVNARRERGADH-VA 857
Query: 306 LVRVEQLSPFPYDLVQQECRKY-QGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATK 130
+VRVEQL PF + + E RKY + E++W Q+E +N G W +VQ + ++ DG+
Sbjct: 858 IVRVEQLYPFAHKAFETELRKYPKATEVIWVQDEPQNQGPWFYVQHHLYENMA-DGQKLG 916
Query: 129 YAGRLPSSSPATGNKFTHMQEQKEMMSKVFGVPKSKLEGF 10
YAGR S+SPA G H ++QK ++ + F +K +GF
Sbjct: 917 YAGRAASASPAVGYLAKHQEQQKALIEQAFA---AKYKGF 953
>gi|33592259|ref|NP_879903.1| 2-oxoglutarate dehydrogenase E1
component [Bordetella pertussis Tohama I]
gi|33602644|ref|NP_890204.1| 2-oxoglutarate dehydrogenase E1
component [Bordetella bronchiseptica RB50]
gi|33571904|emb|CAE41422.1| 2-oxoglutarate dehydrogenase E1 component
[Bordetella pertussis Tohama I]
gi|33577086|emb|CAE35642.1| 2-oxoglutarate dehydrogenase E1 component
[Bordetella bronchiseptica RB50]
Length = 956
Score = 701 bits (1808), Expect = 0.0
Identities = 413/1000 (41%), Positives = 579/1000 (57%), Gaps = 23/1000 (2%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L G ++ Y+E++YE++L +P SV +W YF ++
Sbjct: 12 YLFGGNAPYVEELYESYLDNPGSVPDNWREYFDQLQHSPATDGQEATR-----------D 60
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISD--------HLKIQLLIRSYQTRGHNIADLDPLG 2605
A A + S A R NA VQ +++ + +Q LI +Y++ G ADLDPL
Sbjct: 61 QAHAPIVESFAQRAR--ANAFVQRVAEPDLSVASKQVSVQSLIAAYRSLGSRWADLDPLK 118
Query: 2604 INSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTS 2425
+ PEL+ +FYGL E DLD+ + T+ + ++TLR+IL+ L+D YC S
Sbjct: 119 RQ----ERPAIPELDPAFYGLTEADLDQVYSAT-NTYFTTASTMTLRDILKALRDTYCRS 173
Query: 2424 TGVEYMHLNNLEQQDWIRRRFEAP-RVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEK 2248
G E+MH+++ + WI++R E+ S ++K+ + ++L S E FL K+ +K
Sbjct: 174 VGAEFMHISDPAAKRWIQQRLESTFSAPVFSTEEKRHILQQLTESEGLERFLHTKYVGQK 233
Query: 2247 RFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTL 2068
RF LEG E I +M +V++ + GV V+GM HRGRLN+L N+ + + ++F
Sbjct: 234 RFSLEGGESFIASMDEVVNHAGESGVQEIVVGMAHRGRLNLLVNIMGKMPGDLFAEFEGK 293
Query: 2067 EPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGD 1888
GDVKYH G + R ++ +A NPSHLE V+PVV G VRA GD
Sbjct: 294 HAEGLTDGDVKYHNGFSSDLSTRGGPVHLSLAF--NPSHLEIVNPVVEGSVRARQERRGD 351
Query: 1887 EKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSR 1711
+ + + +L+HGDAAFAGQGVV+ET NL Y T G +HIV+NNQIGFTT DPR SR
Sbjct: 352 GEGKQVLPVLVHGDAAFAGQGVVMETLNLAQTRGYGTGGTLHIVINNQIGFTTSDPRDSR 411
Query: 1710 SSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNEL 1531
S+ YCTDV +++ P+FHVN DDPEAV+ +A D+R F+ DV++D+VC+R+ GHNE
Sbjct: 412 STLYCTDVVKMIEAPVFHVNGDDPEAVVFATRLALDYRMQFRHDVVLDIVCFRKLGHNEQ 471
Query: 1530 DEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKV 1351
D P TQPLMY+RI + Y +K+ +GV E + + Y ++ED + V
Sbjct: 472 DTPSLTQPLMYKRIGHHPGTRKLYADKLTTQGVLAEGDADQLVKDYRQLMEDGQRTIEPV 531
Query: 1350 -TYVRNR---DW---LDSPWDDFFKKRDPL-KLPSTGXXXXXXXXXIGKFSQYPEGFNLH 1195
T +++ DW L + W D PL +L G + + PEGF +H
Sbjct: 532 LTDYKSKYAIDWSPFLGAKWTDQADTAVPLAELKRIGE----------RITTVPEGFTVH 581
Query: 1194 RGLERTLKGRQQMLKDN-SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLH 1018
+ + L R+ M K +LDW GE LAF +L+ G VR++GQD RGTF+HRH VLH
Sbjct: 582 PLVAKLLNDRRNMAKGEVNLDWGMGEHLAFATLVASGYAVRITGQDSGRGTFTHRHAVLH 641
Query: 1017 DQKVDQ---KIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFG 847
DQ ++ Y PL ++SEGQ +TV +S LSE AVL FE GYS +PN+L IWEAQFG
Sbjct: 642 DQNRERWNDGFYVPLQNVSEGQAPFTVIDSVLSEEAVLAFEYGYSSAEPNTLTIWEAQFG 701
Query: 846 DFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI 667
DF N AQ +IDQFI++G++KW RQSGL ++LPHGYEG GPEHSS R ERFLQ+C
Sbjct: 702 DFVNGAQVVIDQFITAGEAKWGRQSGLTLMLPHGYEGQGPEHSSGRIERFLQLC------ 755
Query: 666 DLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHP 487
D N V T+ A I+HLLRRQ+ PFRKP V+F+PKSLLR+
Sbjct: 756 ----------------ADHNIQVVQPTSAAQIFHLLRRQMIRPFRKPLVIFTPKSLLRNK 799
Query: 486 MARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVA 307
A SP+ D GS F+ VI E S VKRV+ C+GKVYYD+V AR+ G ++ VA
Sbjct: 800 DAGSPLTDLAGGS-FRPVIGEVD-ESIKAASVKRVLACSGKVYYDLVNARRERGADH-VA 856
Query: 306 LVRVEQLSPFPYDLVQQECRKY-QGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATK 130
+VRVEQL PF + + E RKY + E++W Q+E +N G W +VQ + ++ DG+
Sbjct: 857 IVRVEQLYPFAHKAFETELRKYPKATEVIWVQDEPQNQGPWFYVQHHLYENMA-DGQKLG 915
Query: 129 YAGRLPSSSPATGNKFTHMQEQKEMMSKVFGVPKSKLEGF 10
YAGR S+SPA G H ++QK ++ + F +K +GF
Sbjct: 916 YAGRAASASPAVGYLAKHQEQQKALIEQAFA---AKYKGF 952
>gi|24213924|ref|NP_711405.1| 2-oxoglutarate dehydrogenase
decarboxylase component [Leptospira interrogans serovar
Lai str. 56601]
gi|45658316|ref|YP_002402.1| oxoglutarate dehydrogenase [Leptospira
interrogans serovar Copenhageni str. Fiocruz L1-130]
gi|24194778|gb|AAN48423.1| 2-oxoglutarate dehydrogenase decarboxylase
component [Leptospira interrogans serovar lai str. 56601]
gi|45601558|gb|AAS71039.1| oxoglutarate dehydrogenase [Leptospira
interrogans serovar Copenhageni str. Fiocruz L1-130]
Length = 920
Score = 699 bits (1804), Expect = 0.0
Identities = 410/974 (42%), Positives = 564/974 (57%), Gaps = 8/974 (0%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G + +E++Y + +P ++ W ++F+ V+ Y G S
Sbjct: 9 LYGENGALLEELYNQYKLNPETLDKEWKSFFQEVDTNGLANGSG-------YTNGNGKSA 61
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 2578
A T + A + R + I L+ +Y+ +GH A LDPLGI +
Sbjct: 62 VATSFTDAQAASIR------------EMGIINLLNAYRRQGHLAAKLDPLGIQKPNRTF- 108
Query: 2577 IPPELELSFYGLGERDLDREFLLPPTTFISEKKS-LTLREILQRLKDIYCTSTGVEYMHL 2401
++ + + D+D T SE + L EI+ + +YC + G E+ +L
Sbjct: 109 ----IDSKLHNISPADID-------TVVDSETLGRVKLAEIVDLYEKVYCNTIGAEHFYL 157
Query: 2400 NNLEQQDWIRRRFEAPR-VTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCE 2224
N E+++W++++ E+P + L K LF++L ++ FE FLAKK+ +KRF LEG E
Sbjct: 158 VNDEEREWLQKKMESPEFLAPLPRGIKLRLFEKLFQADYFETFLAKKYVGKKRFSLEGGE 217
Query: 2223 VLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGS- 2047
IP + +++ + +D VIGM HRGRLNVL N+ +P + I ++F D S
Sbjct: 218 SFIPLLDTIVEEAGYHQMDGLVIGMAHRGRLNVLVNIIEKPASLIFAEFEEKTDKDNLSY 277
Query: 2046 GDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTM 1867
DVKYHLG R+ S K VK+++ NPSHLE VDPVV G VRA GD+ + M
Sbjct: 278 ADVKYHLGYSNSRMTT-SGKEVKLSLAFNPSHLECVDPVVTGSVRARQTLIGDKDRSKYM 336
Query: 1866 AILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDV 1687
IL+HGDAAFAGQGVV ET NL +L YTT G HIVVNNQIGFTT P SRS+ Y TD+
Sbjct: 337 PILIHGDAAFAGQGVVAETLNLMNLEGYTTGGTFHIVVNNQIGFTTLPDESRSTLYATDL 396
Query: 1686 GRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQP 1507
+ PI HVN DDPEAV V + ++R+ FKKD I+DLVCYRR GHNE DEP FTQP
Sbjct: 397 AKGFQIPIIHVNGDDPEAVYRVVKLGMEYRQKFKKDFIIDLVCYRRLGHNETDEPAFTQP 456
Query: 1506 LMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSI--LEDAYENAQKVTYVRNR 1333
MY IK ++ Y+++++ EG ++ + + K GS+ LED+++ A++
Sbjct: 457 KMYAIIKNHPPTVKLYEKRLVEEGDIPQEDI--DFIKNGSMHGLEDSFQRAKEQDVKIRV 514
Query: 1332 DWLDSPWDDFFKKRDPL-KLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQM 1156
D + W F K D L P+T + + P+GF + L + L+ R++M
Sbjct: 515 DTMQGVWSKFSK--DSLDSEPATKLLAEQMHGIVQALTSVPQGFTPNSKLVKLLQSRKEM 572
Query: 1155 LKDN-SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLN 979
+ +DW EAL+FGS+L+ G +RLSGQD QRGTFSHRH VL D ++K Y PLN
Sbjct: 573 AEGKIPVDWGFAEALSFGSILESGFRIRLSGQDSQRGTFSHRHAVLVDTNTNEK-YIPLN 631
Query: 978 DLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISS 799
+S Q + + NSSLSE++VLGFE GYS+ DPN+LV+WEAQFGDF+N+AQ I DQFISS
Sbjct: 632 HISSKQAKAEIINSSLSEFSVLGFEYGYSLSDPNALVMWEAQFGDFANSAQVIFDQFISS 691
Query: 798 GQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQL 619
+ KW R SGL+MLLPHGYEG GPEHSSAR ERFLQ+C D
Sbjct: 692 SEVKWQRLSGLIMLLPHGYEGQGPEHSSARLERFLQLCALD------------------- 732
Query: 618 HDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQ 439
N V N TT A +HLLRRQ+ +RKP V+ +PKSLLR P + SPVED G+ +
Sbjct: 733 ---NMQVCNLTTAAQYFHLLRRQMLRNYRKPLVIVTPKSLLRFPASLSPVEDILQGAFRE 789
Query: 438 RVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQ 259
+I ++G+ P +++VVF GKVYYD++ K K +VALVRVEQ+ PFP +Q
Sbjct: 790 ILIDDSGS---KPDKIEKVVFSAGKVYYDLM-KYKDENKIKNVALVRVEQIYPFPAKEIQ 845
Query: 258 QECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKF 82
+ ++ A + +W QEE KN GAW FV+ RI LL + R YAGR S SPA G+
Sbjct: 846 SSLKTFKNAKQFVWCQEEPKNQGAWFFVRERIEELLPGNARLV-YAGRHESPSPAAGHMK 904
Query: 81 THMQEQKEMMSKVF 40
H+QEQ +++ F
Sbjct: 905 LHLQEQDQLVLDAF 918
>gi|129036|sp|P20707|ODO1_AZOVI 2-oxoglutarate dehydrogenase E1
component (Alpha-ketoglutarate dehydrogenase)
gi|77878|pir||S07776 oxoglutarate dehydrogenase (lipoamide) (EC
1.2.4.2) - Azotobacter vinelandii
gi|39232|emb|CAA36680.1| 2-oxoglutarate dehydrogenase [Azotobacter
vinelandii]
Length = 943
Score = 697 bits (1800), Expect = 0.0
Identities = 403/989 (40%), Positives = 562/989 (56%), Gaps = 10/989 (1%)
Frame = -1
Query: 2970 SVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXX 2791
SV + + L+G ++ Y+E++YE +L DP++V W YF +
Sbjct: 4 SVMQRMWNSAHLSGGNAAYVEELYELYLHDPNAVPEEWRTYFEKLPAEAGTSTDVPHAPV 63
Query: 2790 XAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDP 2611
L + AQ +S+ +T + +++ LI++Y+TRGH + LDP
Sbjct: 64 RDQFVLLAKNQRRAQPVATSSVSTEHEKK--------QVEVLRLIQAYRTRGHQASQLDP 115
Query: 2610 LGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYC 2431
LG+ T P +L ++ YGL DLD F K+ TLREILQ L++ YC
Sbjct: 116 LGL----WQRTAPSDLSITHYGLTNADLDTPFRTGELYI--GKEEATLREILQALQETYC 169
Query: 2430 TSTGVEYMHLNNLEQQDWIRRRFEAPRVTEL-SHDQKKVLFKRLIRSTKFEEFLAKKWPS 2254
+ G E+ H+ + EQ++W +R E+ R + S + K L +RL + E++L K+P
Sbjct: 170 RTIGAEFTHIVDSEQRNWFAQRLESVRGRPVYSKEAKSHLLERLSAAEGLEKYLGTKYPG 229
Query: 2253 EKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS 2074
KRFGLEG E L+P + ++I S + G VIGM HRGRLN+L N + + +F
Sbjct: 230 TKRFGLEGGESLVPVVDEIIQRSGSYGTKEVVIGMAHRGRLNLLVNALGKNPRDLFDEFE 289
Query: 2073 TLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYA 1894
+ GSGDVKYH G + S V +A+ NPSHLE V PVV G VRA
Sbjct: 290 GKHLVELGSGDVKYHQGFSSNVMT--SGGEVHLAMAFNPSHLEIVSPVVEGSVRARQDRR 347
Query: 1893 GDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRS 1717
D ++ + I +HGD+AFAGQGVV+ETF + + Y T G IHIVVNNQ+GFTT +P
Sbjct: 348 VDATGEKVVPISIHGDSAFAGQGVVMETFQMSQIRGYKTGGTIHIVVNNQVGFTTSNPVD 407
Query: 1716 SRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHN 1537
+RS+ YCTD +++ P+ HVN DDPEAV+ V +A D+R FK+DV++DLVCYRR GHN
Sbjct: 408 TRSTEYCTDPAKMIQAPVLHVNGDDPEAVLFVTQLAVDYRMQFKRDVVIDLVCYRRRGHN 467
Query: 1536 ELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQ 1357
E DEP TQPLMYQ+I + T E Y + ++ EG +++ V+ ++ +Y + L++ +
Sbjct: 468 EADEPSGTQPLMYQKIAKQPTTRELYADALVKEGSLSQEEVQAKVDEYRTALDNGQHVLK 527
Query: 1356 KVTYVRNR----DWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRG 1189
+ N DW + + D T K Q PEGF + R
Sbjct: 528 SLVKEPNTELFVDWTPYLGHAWTARHD------TSFELKTLQELNAKLLQIPEGFVVQRQ 581
Query: 1188 LERTLKGRQQM-LKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQ 1012
+ + L+ R +M + ++W C E LA+ +LLKEG VR++GQDV RGTFSHRH LH+Q
Sbjct: 582 VAKILEDRGRMGVGAMPINWGCAETLAYATLLKEGHPVRITGQDVGRGTFSHRHAALHNQ 641
Query: 1011 KVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNT 832
K D Y PL +L EGQ ++ + +S LSE AVL FE GY+ PN+LVIWEA GDF+N
Sbjct: 642 K-DASRYIPLQNLYEGQPKFELYDSFLSEEAVLAFEYGYATTTPNALVIWEASSGDFANG 700
Query: 831 AQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKI 652
AQ +IDQFISSG++KW GL MLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 701 AQVVIDQFISSGETKWGALCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEQ-------- 752
Query: 651 AFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSP 472
N V TTPA +YH+LRRQV P RKP V +PKSLLRH A S
Sbjct: 753 --------------NIQVCVPTTPAQVYHMLRRQVIRPLRKPLVALTPKSLLRHKSAIST 798
Query: 471 VEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVE 292
+ED GS F V+PE S +P V+R+V C+GKVYYD++ R G+E D+A+VR+E
Sbjct: 799 LEDLALGS-FHPVLPE--VDSLDPKKVERLVLCSGKVYYDLLDKRHAEGRE-DIAIVRIE 854
Query: 291 QLSPFPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLLSIDGRA--TKYAG 121
QL PFP + + + Y + ++W QEE N GAW Q + + S + +YAG
Sbjct: 855 QLYPFPEEELAEVMAPYTNLKHVVWCQEEPMNQGAWYCSQHHMRRVASAHKKELFLQYAG 914
Query: 120 RLPSSSPATGNKFTHMQEQKEMMSKVFGV 34
R S++PA G H ++Q++++ F V
Sbjct: 915 REASAAPACGYASMHAEQQEKLLQDAFTV 943
>gi|28869401|ref|NP_792020.1| 2-oxoglutarate dehydrogenase, E1
component [Pseudomonas syringae pv. tomato str. DC3000]
gi|28852642|gb|AAO55715.1| 2-oxoglutarate dehydrogenase, E1 component
[Pseudomonas syringae pv. tomato str. DC3000]
Length = 943
Score = 697 bits (1799), Expect = 0.0
Identities = 406/993 (40%), Positives = 562/993 (55%), Gaps = 13/993 (1%)
Frame = -1
Query: 2973 QSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXX 2794
+SV + + L+G ++ Y+E++YE +L DP++V W YF+ +
Sbjct: 3 ESVMQRMWNSAHLSGGNAAYVEELYELYLHDPNAVPEEWRTYFQKLPADGSSATDVSHST 62
Query: 2793 XXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLD 2614
+ L + AQ ++ + S + +++ LI++Y+ RGH A LD
Sbjct: 63 IRDHFVLLAKNQRRAQPVSAGS--------VSSEHEKKQVEVLRLIQAYRMRGHQAAQLD 114
Query: 2613 PLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIY 2434
PLG+ P +L ++ YGL DLD F FI K+ +LREI + L+ Y
Sbjct: 115 PLGL----WQRPAPADLSINHYGLTNADLDTTFRAGDL-FIG-KEEASLREIHEALQQTY 168
Query: 2433 CTSTGVEYMHLNNLEQQDWIRRRFEAPRVTE-LSHDQKKVLFKRLIRSTKFEEFLAKKWP 2257
C + G E+ H+ + EQ++W +R E+ R S D + L +R+ + E++L K+P
Sbjct: 169 CRTIGSEFTHIVDSEQRNWFMQRLESVRGRPAFSADIQSHLLERVTAAEGLEKYLGTKYP 228
Query: 2256 SEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQF 2077
KRFGLEG E LIP + ++I S + G VIGM HRGRLNVL N + + +F
Sbjct: 229 GTKRFGLEGGESLIPMLDELIQRSGSYGTKEVVIGMAHRGRLNVLVNTFGKNPRDLFDEF 288
Query: 2076 STLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFY 1897
+ + GSGDVKYH G + + V +A+ NPSHLE V PVV G VRA
Sbjct: 289 EGKKKVELGSGDVKYHQGFSSNVMTAGGE--VHLAMAFNPSHLEIVSPVVEGSVRARQDR 346
Query: 1896 AGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFT-TDPR 1720
D D+ + I LHGDAAFAGQGVV+ETF + + T G IHIV+NNQ+GFT ++P
Sbjct: 347 RNDPNGDKVLPISLHGDAAFAGQGVVMETFQMSQTRGFKTGGTIHIVINNQVGFTISNPL 406
Query: 1719 SSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGH 1540
SRS+ Y TDV +++ PI HVN DDPEAVM V +A D+R FK+D+++DLVCYRR GH
Sbjct: 407 DSRSTEYATDVAKMIQAPILHVNGDDPEAVMFVTQLAIDYRMQFKRDIVIDLVCYRRRGH 466
Query: 1539 NELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAY--- 1369
NE DEP TQPLMYQ+I + +T E Y E ++ GV +E V+ ++ Y S L++
Sbjct: 467 NEADEPSGTQPLMYQQITKQRTTRELYAEHLIKTGVLDEARVQAKVDDYRSALDNGLHVV 526
Query: 1368 ----ENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFN 1201
+ K +V R +L W R LK K + PEGF
Sbjct: 527 KSLVKEPNKELFVDWRPYLGHAWTARHDTRFDLK---------TLQELSAKLMELPEGFV 577
Query: 1200 LHRGLERTLKGRQQMLKDN-SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHV 1024
+ R +++ + RQ+M ++W E +A+ +L EG +R++GQD+ RGTFSHRH V
Sbjct: 578 VQRQVQKIYEDRQKMQAGGLPINWGYAETMAYATLAFEGHPIRMTGQDIGRGTFSHRHAV 637
Query: 1023 LHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGD 844
LH+QK D Y PL +L GQ + + +S LSE AVL FE GYS P++LVIWEAQFGD
Sbjct: 638 LHNQK-DAGTYIPLQNLYAGQPRFDLYDSFLSEEAVLAFEYGYSTTQPDALVIWEAQFGD 696
Query: 843 FSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEID 664
F+N AQ ++DQFI+SG+ KW R GL MLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 697 FANGAQVVVDQFITSGEHKWGRLCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEH---- 752
Query: 663 LEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPM 484
N V TTPA IYHLLRRQV P RKP +V +PKSLLRH +
Sbjct: 753 ------------------NIQVCVPTTPAQIYHLLRRQVIRPLRKPLIVLTPKSLLRHKL 794
Query: 483 ARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVAL 304
A S +ED GS FQ VIPE + +P V R+V C+GKVYYD++ R+ G+E D+A+
Sbjct: 795 AVSTLEDLAEGS-FQTVIPE--IDTLDPAKVTRLVLCSGKVYYDLLEKRRAEGRE-DIAI 850
Query: 303 VRVEQLSPFPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLLSIDGR--AT 133
VR+EQL PFP D + + Y + ++W QEE N GAW Q + + R
Sbjct: 851 VRLEQLYPFPEDDLMETIAPYTNLQHVVWCQEEPMNQGAWYSSQHHLRRSMGNHKRELVL 910
Query: 132 KYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGV 34
+YAGR S++PA G H ++Q++++ F V
Sbjct: 911 EYAGRDASAAPACGYASMHAEQQEKLLRDAFTV 943
>gi|46310766|ref|ZP_00211388.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Burkholderia cepacia R18194]
Length = 950
Score = 695 bits (1794), Expect = 0.0
Identities = 407/987 (41%), Positives = 571/987 (57%), Gaps = 15/987 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L G ++ Y+E++Y+A+L +P+SV +W YF ++ +
Sbjct: 9 YLFGGNASYVEELYDAYLNNPASVPENWREYFDALQNVPATDGTNANDVAH-----FPIV 63
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDD 2581
+ A+ ++A R ++ ++ + + +Q LI +Y+ G A+LDPL +
Sbjct: 64 ESFAERAKANAFIPR-ESTTNLAAARKQVHVQSLISAYRFLGSQWANLDPLKRR----ER 118
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
PELE +FY E DLD+ + F ++ SL R+I++ L+D YC + G EYM++
Sbjct: 119 PAIPELEPAFYDFSEGDLDQTYSASNLYFGFDQASL--RDIVKGLRDTYCGTIGAEYMYI 176
Query: 2400 NNLEQQDWIRRRFEAPRVT-ELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCE 2224
++ EQ+ W + R E+ R T S D+KK + RL + E +L K+ +KRF LEG E
Sbjct: 177 SDPEQKRWWQERLESTRATPNFSADEKKHILNRLTAAEGLERYLHTKYVGQKRFSLEGGE 236
Query: 2223 VLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSG 2044
I AM +V+ S GV +IGM HRGRLNVL N + A + ++F D +G
Sbjct: 237 SFIAAMDEVVQHSGKRGVQEIIIGMAHRGRLNVLVNTLGKMPADLFAEFEGKHVDDLPAG 296
Query: 2043 DVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMA 1864
DVKYH G + ++ +A NPSHLE V+PVV G +A GDE + +
Sbjct: 297 DVKYHKGFSSDVSTEGGPVHLSLAF--NPSHLEIVNPVVEGSAKARMDRRGDEDGLQVLP 354
Query: 1863 ILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDV 1687
+ +HGDAAFAGQGVV+ET NL Y THG +HIV+NNQIGFTT DPR +RS+ YCTDV
Sbjct: 355 VQIHGDAAFAGQGVVMETLNLAQTRGYGTHGTLHIVINNQIGFTTSDPRDARSTLYCTDV 414
Query: 1686 GRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQP 1507
+++ P+ HVN DDPEAV+ +A D+R F KDV++D+VC+R+ GHNE D P TQP
Sbjct: 415 VKMIEAPVLHVNGDDPEAVVLAIQIAIDYRMQFHKDVVIDIVCFRKLGHNEQDTPAVTQP 474
Query: 1506 LMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKV-TYVRNR- 1333
LMY++I Q Y EK++ +GV + + + Y ++D + V + +++
Sbjct: 475 LMYKKIAQHPGTRALYAEKLVQQGVISAEDADNFVKAYRKAMDDGHHTVDPVLSNYKSKY 534
Query: 1332 --DW---LDSPWDDFFKKRDPL-KLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLK 1171
DW L+ W D PL +L G + + PE F +H +ER +
Sbjct: 535 AVDWVPFLNRKWTDAADTAVPLAELKRLGE----------RITTVPENFKVHPLVERVIN 584
Query: 1170 GRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQ-- 1000
R+ M + D LDW GE LAF SL+ G VRL+GQD RGTF+HRH VLHDQ ++
Sbjct: 585 DRRNMARGDQPLDWGMGEHLAFASLVASGYSVRLTGQDSGRGTFTHRHAVLHDQNRERWN 644
Query: 999 -KIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQC 823
Y PL +++EGQ ++TV +S LSE AVLGFE GYS +PN+LV+WEAQFGDF N AQ
Sbjct: 645 DGTYVPLQNIAEGQAKFTVIDSVLSEEAVLGFEYGYSTAEPNTLVLWEAQFGDFVNGAQV 704
Query: 822 IIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFE 643
+IDQFISSG+ KW R SGL MLLPHGYEG GPEHSS R ERFLQ+C
Sbjct: 705 VIDQFISSGEVKWGRVSGLTMLLPHGYEGQGPEHSSTRIERFLQLC-------------- 750
Query: 642 GTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVED 463
D N V TTPA I+HLLRRQ+ FRKP +V +PKSLLRH A S + +
Sbjct: 751 --------ADHNMQVVQPTTPAQIFHLLRRQMIRLFRKPLIVATPKSLLRHKEAVSDLSE 802
Query: 462 FQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLS 283
GS FQ V+ ET + VKRV+ C+G+VYYD+VA R+ K NDVA++R+EQL
Sbjct: 803 LAKGS-FQPVLGETDG-GIDAKKVKRVLACSGRVYYDLVAHRRE-AKANDVAIIRIEQLY 859
Query: 282 PFPYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSS 106
PF + + E +KY+ A E++W Q+E +N G W +V+ + + +G+ Y+GR S+
Sbjct: 860 PFAHKQFEAEMKKYENATEVVWVQDEPQNQGPWFYVEHHLKEGMK-EGQKLAYSGRPASA 918
Query: 105 SPATGNKFTHMQEQKEMMSKVFGVPKS 25
SPA G H ++QK ++ FG KS
Sbjct: 919 SPAVGYYAKHYEQQKALIEGAFGRLKS 945
>gi|39997544|ref|NP_953495.1| 2-oxoglutarate dehydrogenase, E1
component [Geobacter sulfurreducens PCA]
gi|39984435|gb|AAR35822.1| 2-oxoglutarate dehydrogenase, E1 component
[Geobacter sulfurreducens PCA]
Length = 894
Score = 694 bits (1790), Expect = 0.0
Identities = 406/973 (41%), Positives = 556/973 (56%), Gaps = 4/973 (0%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
F G+ +IE ++++W DP+SV W A+F E LG
Sbjct: 3 FAAGADPEFIESLFQSWQADPASVSAEWRAFFTGYE--------------------LGRG 42
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDD 2581
+A+ T A+ QS D LI Y+ GH +A DPL +
Sbjct: 43 EPSAECPTPEL--------AAKQSAVDS-----LIYRYRDLGHLLACTDPLSPCKLE--- 86
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
P L L Y L + DLDR F F+ K TLREIL L++ YC S GVE+MH+
Sbjct: 87 --HPLLALEQYDLDQSDLDRTF--RARRFL--KSEATLREILATLRETYCRSVGVEFMHI 140
Query: 2400 NNLEQQDWIRRRFEAPR-VTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCE 2224
+ ++ W+ R E R +S DQK + ++L ++ FEEFL +K+ +KRF LEG E
Sbjct: 141 QDPAERTWLIERMEPVRNRPPVSLDQKLRILEKLREASLFEEFLHRKFLGQKRFSLEGGE 200
Query: 2223 VLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEPADEGS 2047
LIPA+ V++ ++ LGVD V+GM HRGRLNVLA + +P+ I ++F+ +E A G
Sbjct: 201 ALIPALDAVVERAARLGVDDLVLGMAHRGRLNVLATIIGKPVENIFAEFADNVELAFVGD 260
Query: 2046 GDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTM 1867
GDVKYH G +R ++ + + NPSHLEAV+PVV GK RA G R +
Sbjct: 261 GDVKYHKGFSSDR-RFADGSSIHLTLAFNPSHLEAVNPVVEGKCRARQDARGPGGDRRVL 319
Query: 1866 AILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDV 1687
+L+HGDAAFAGQGVV ET NL L Y T G +HIV+NNQIGFTT P +RSS Y TD
Sbjct: 320 PVLIHGDAAFAGQGVVAETLNLSQLEGYRTGGTLHIVINNQIGFTTVPADARSSLYATDT 379
Query: 1686 GRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQP 1507
++V P+FHV+ +DPEA +HV +A ++R+TF +DV+V+++CYRRHGHNE DEP FTQP
Sbjct: 380 AKIVAAPVFHVHGEDPEAAVHVMELALEYRQTFGRDVVVEIICYRRHGHNEGDEPYFTQP 439
Query: 1506 LMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDW 1327
+MY RIK E Y +++ EGV ++ G + E + V
Sbjct: 440 VMYGRIKDRPPVHELYADRLAEEGVPRDRLDAMTAAIAGRLEESLGAPPRPVA-----GG 494
Query: 1326 LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLK- 1150
+ W ++ + P K+ TG + PEGF+ H + L+ R + ++
Sbjct: 495 FEGKWGEYRRDYSPAKV-DTGVDAARLRQLAEGLAGVPEGFSAHPKVATILQRRLKAVQA 553
Query: 1149 DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLS 970
+DW E LA+G+LL EG +RLSG+D +RGTF HRH VLHD + + PL+ +
Sbjct: 554 GEGIDWGNAETLAYGTLLAEGTSIRLSGEDSRRGTFGHRHAVLHDMNT-EAFHVPLDGAA 612
Query: 969 EGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQS 790
G + +S LSE+AVLG+E GYS+ P LVIWEAQFGDF+N AQ IIDQFI+ G+S
Sbjct: 613 TGGAVFRAWDSMLSEFAVLGYEYGYSVQSPEMLVIWEAQFGDFANGAQVIIDQFIAGGES 672
Query: 789 KWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDT 610
KW R SGLVMLLPHGYEG G EHSSAR ER+LQ+C +D
Sbjct: 673 KWERVSGLVMLLPHGYEGQGAEHSSARIERYLQLCADD---------------------- 710
Query: 609 NWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVI 430
N VA +TPA ++HLLRRQV PFRKP VVF+PKSLLRHP S +E+ SG F+ VI
Sbjct: 711 NLQVAYPSTPAQLFHLLRRQVKQPFRKPLVVFTPKSLLRHPRCVSRLEEL-SGGWFREVI 769
Query: 429 PETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQEC 250
P P +P ++R++ C+GK+YY+++ R D A+VR+EQL P DL+++
Sbjct: 770 P----PVADPEKIRRLLLCSGKIYYELL-ERMERDAVADTAIVRIEQLYPLRTDLLREAV 824
Query: 249 RKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHM 73
++GA I W QEE +NMGAWSF++P + L GR +Y GR + PA G+ H
Sbjct: 825 APFRGAGSIAWVQEEPRNMGAWSFLRPHLADLF---GREPRYVGRPDNDVPAVGSHRLHG 881
Query: 72 QEQKEMMSKVFGV 34
EQ+ ++++ V
Sbjct: 882 VEQERVVTEALAV 894
>gi|46318668|ref|ZP_00219106.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Burkholderia cepacia R1808]
Length = 950
Score = 693 bits (1788), Expect = 0.0
Identities = 405/987 (41%), Positives = 572/987 (57%), Gaps = 15/987 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L G ++ Y+E++Y+A+L +P+SV +W YF ++ +
Sbjct: 9 YLFGGNASYVEELYDAYLNNPASVPENWREYFDALQNVPATDGSNANDVAHY-----PIV 63
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDD 2581
+ A+ ++A R ++ +++ + + +Q LI +Y+ G A+LDPL +
Sbjct: 64 ESFAERAKANAFIPR-ESGSNLATARKQVHVQSLISAYRFLGSQWANLDPLKRR----ER 118
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
PELE +FY E DLD+ + F ++ SL R+I++ L+D YC + G EYM++
Sbjct: 119 PAIPELEPAFYDFSEGDLDQTYSASNLYFGFDQASL--RDIVKGLRDTYCGTIGAEYMYI 176
Query: 2400 NNLEQQDWIRRRFEAPRVTE-LSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCE 2224
++ EQ+ W + R E+ R T S D+KK + RL + E +L K+ +KRF LEG E
Sbjct: 177 SDPEQKRWWQERLESTRATPAFSADKKKHILNRLTAAEGLERYLHTKYVGQKRFSLEGGE 236
Query: 2223 VLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSG 2044
I AM +V+ + GV +IGM HRGRLNVL N + A + ++F D +G
Sbjct: 237 SFIAAMDEVVQHAGKSGVQEIIIGMAHRGRLNVLVNTLGKMPADLFAEFEGKHVDDLPAG 296
Query: 2043 DVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMA 1864
DVKYH G + ++ +A NPSHLE V+PVV G +A GD+ + +
Sbjct: 297 DVKYHKGFSSDVSTEGGPVHLSLAF--NPSHLEIVNPVVEGSAKARMDRRGDDDGLQVLP 354
Query: 1863 ILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDV 1687
+ +HGDAAFAGQGVV+ET NL Y THG +HIV+NNQIGFTT DPR +RS+ YCTDV
Sbjct: 355 VQIHGDAAFAGQGVVMETLNLAQTRGYGTHGTLHIVINNQIGFTTSDPRDARSTLYCTDV 414
Query: 1686 GRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQP 1507
+++ P+ HVN DDPEAV+ +A D+R F KDV++D+VC+R+ GHNE D P TQP
Sbjct: 415 VKMIEAPVLHVNGDDPEAVVLAIQIAIDYRMQFHKDVVIDIVCFRKLGHNEQDTPAVTQP 474
Query: 1506 LMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKV-TYVRNR- 1333
LMY++I Q Y EK++ +GV + + Y ++D + V + +++
Sbjct: 475 LMYKKIAQHPGTRALYAEKLVQQGVITAEDADGYVKAYRKAMDDGHHTVDPVLSNYKSKY 534
Query: 1332 --DW---LDSPWDDFFKKRDPL-KLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLK 1171
DW L+ W D PL +L G + + PE F +H +ER +
Sbjct: 535 AVDWVPFLNRKWTDAADTAVPLAELKRLGE----------RITTVPENFKVHPLVERVIN 584
Query: 1170 GRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQ-- 1000
R+ M + D LDW GE LAF SL+ G VRL+GQD RGTF+HRH VLHDQ ++
Sbjct: 585 DRRNMARGDQPLDWGMGEHLAFASLVASGYAVRLTGQDSGRGTFTHRHAVLHDQNRERWN 644
Query: 999 -KIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQC 823
Y PL +++EGQ ++TV +S LSE AVLGFE GYS +PN+LV+WEAQFGDF N AQ
Sbjct: 645 DGTYVPLQNIAEGQAKFTVIDSVLSEEAVLGFEYGYSTAEPNTLVLWEAQFGDFVNGAQV 704
Query: 822 IIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFE 643
+IDQFISSG+ KW R SGL MLLPHGYEG GPEHSS R ERFLQ+C
Sbjct: 705 VIDQFISSGEVKWGRVSGLTMLLPHGYEGQGPEHSSTRIERFLQLC-------------- 750
Query: 642 GTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVED 463
D N V TTPA I+HLLRRQ+ FRKP ++ +PKSLLRH A S + +
Sbjct: 751 --------ADHNMQVVQPTTPAQIFHLLRRQMIRLFRKPLIIATPKSLLRHKEAVSDLSE 802
Query: 462 FQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLS 283
GS FQ V+ ET +P VKRV+ C+G+VYYD+VA R+ K NDVA++R+EQL
Sbjct: 803 LAKGS-FQPVLGETDG-GIDPKKVKRVLACSGRVYYDLVAHRRE-AKANDVAIIRIEQLY 859
Query: 282 PFPYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSS 106
PF + + E +KY+ A E++W Q+E +N G W +V+ + + +G+ Y+GR S+
Sbjct: 860 PFAHKQFEAEMKKYEHATEVVWVQDEPQNQGPWFYVEHHLKEGMK-EGQKLAYSGRPASA 918
Query: 105 SPATGNKFTHMQEQKEMMSKVFGVPKS 25
SPA G H ++QK ++ FG KS
Sbjct: 919 SPAVGYYAKHYEQQKALIEGAFGRLKS 945
>gi|48769526|ref|ZP_00273871.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Ralstonia metallidurans CH34]
Length = 950
Score = 692 bits (1787), Expect = 0.0
Identities = 415/991 (41%), Positives = 565/991 (56%), Gaps = 14/991 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L G ++ Y+E++YEA+LQ+PSSV +W AYF ++ A + +
Sbjct: 10 YLFGGNAPYVEELYEAYLQNPSSVPDNWRAYFDAMQNVPAADGSN--------ARDIPHA 61
Query: 2760 PAAAQVT--TSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADL 2587
P A P + +A + LI +Y+ G + ADLDPL
Sbjct: 62 PIVASFAERAKQGPIKTIVASADSDMGRKRVAATQLIAAYRNIGSHWADLDPL-----KR 116
Query: 2586 DDTIP-PELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEY 2410
+ P P+L+ +FYG E DLD F T F K+S++LRE+L L++ YC + G E+
Sbjct: 117 QERPPLPDLDPAFYGFSEADLDIVFNASNTYF--GKESMSLRELLNNLRETYCGTIGAEF 174
Query: 2409 MHLNNLEQQDWIRRRFEAPRVTEL-SHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLE 2233
M++++ Q+ W + R E R + + ++KK + RL + E FL K+ +KRF LE
Sbjct: 175 MYVSDQAQKRWWQERLETTRSKPVFTLEKKKHILDRLTAAEGLERFLHTKYVGQKRFSLE 234
Query: 2232 GCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADE 2053
G E I AM ++I + T GV VIGM HRGRLNVL N + A + ++F D
Sbjct: 235 GGESFIAAMDELIQHAGTKGVQEIVIGMAHRGRLNVLVNTLGKMPADLFAEFEGKHVDDL 294
Query: 2052 GSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDR 1873
+GDVKYH G + ++ +A NPSHLE V+PVV G +A GD
Sbjct: 295 PAGDVKYHKGFSSDVSTEGGPVHLSLAF--NPSHLEIVNPVVEGSSKARQERRGDVGHKE 352
Query: 1872 TMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYC 1696
+ + +HGDAAFAGQGVV+ET NL Y T G +H+V+NNQIGFTT DPR +RS+ YC
Sbjct: 353 VLPVQVHGDAAFAGQGVVMETLNLAQTRGYGTGGTMHLVINNQIGFTTSDPRDARSTLYC 412
Query: 1695 TDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMF 1516
TDV +++ P+ HVN DDPEAV++ +A D+R F KDV+VD++C+R+ GHNE D P
Sbjct: 413 TDVVKMIEAPVLHVNGDDPEAVVYAMQLAVDFRMEFNKDVVVDIICFRKLGHNEQDTPAM 472
Query: 1515 TQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKV-TYVR 1339
TQPLMY++I Q + Y +K++ + + ++ E + Y + ++ V + +
Sbjct: 473 TQPLMYKKIGQHPGTRKLYADKLVAQSLTPAEFGDELVKDYRAAMDAGKHTVDPVLSNFK 532
Query: 1338 NR---DWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKG 1168
N+ DW+ F R T + + PE F LH +E+ +K
Sbjct: 533 NKFAVDWMP------FLNRKWTDAADTAVPMTELKRLAERITTIPEHFKLHPLVEKVVKD 586
Query: 1167 RQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQ---KVDQ 1000
R M + + LDW GE LAF SL+ G VR++GQD RGTF+HRH VLHDQ + D
Sbjct: 587 RSNMGRGEQMLDWGMGEHLAFASLVASGYPVRITGQDAGRGTFTHRHAVLHDQARERWDA 646
Query: 999 KIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCI 820
Y PL ++SE Q +TV +S LSE AVLGFE GYS +PN+LVIWEAQFGDF N AQ +
Sbjct: 647 GSYVPLQNVSENQAPFTVIDSVLSEEAVLGFEYGYSTAEPNALVIWEAQFGDFVNGAQVV 706
Query: 819 IDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEG 640
IDQFISSG+ KW R SGL M+LPHGYEG GPEHSSAR ERFLQ+C
Sbjct: 707 IDQFISSGEVKWGRASGLTMMLPHGYEGQGPEHSSARIERFLQLC--------------- 751
Query: 639 TFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDF 460
D N V TTPA I+HLLRRQ+ FRKP V+ +PKSLLR A SP+ D
Sbjct: 752 -------ADHNIQVVQPTTPAQIFHLLRRQMIRLFRKPLVIMTPKSLLRSKDAVSPLSDL 804
Query: 459 QSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSP 280
G +F+ VIP+ N VKRV+ C+GKVYYD+V R+ G D A++R+EQL P
Sbjct: 805 AKG-HFETVIPD--HEELNASKVKRVIMCSGKVYYDLVNTRRERG-ATDTAIIRMEQLYP 860
Query: 279 FPYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSS 103
FP+ V E +KY GA EILW Q+E +N GAW FVQ I ++ +G+ YAGR S+S
Sbjct: 861 FPHKAVAAELKKYPGATEILWCQDEPQNQGAWFFVQHYIMENMT-EGQKLGYAGRPASAS 919
Query: 102 PATGNKFTHMQEQKEMMSKVFGVPKSKLEGF 10
PA G H ++QK ++ F SKL+GF
Sbjct: 920 PAVGYYAKHNEQQKALLDAAF----SKLKGF 946
>gi|50085916|ref|YP_047426.1| 2-oxoglutarate decarboxylase, component
of the 2-oxoglutarate dehydrogenase complex (E1)
[Acinetobacter sp. ADP1]
gi|49531892|emb|CAG69604.1| 2-oxoglutarate decarboxylase, component
of the 2-oxoglutarate dehydrogenase complex (E1)
[Acinetobacter sp. ADP1]
Length = 946
Score = 692 bits (1786), Expect = 0.0
Identities = 406/994 (40%), Positives = 560/994 (55%), Gaps = 14/994 (1%)
Frame = -1
Query: 2973 QSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXX 2794
Q VA A++ + L+ S+ YIE++YE +L P+SV W YF
Sbjct: 2 QDVADALRLDTELSADSAAYIEELYEQYLTSPTSVTEDWRQYFDKFPK------------ 49
Query: 2793 XXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQL----LIRSYQTRGHNI 2626
G S Q + R+ SDH + Q+ LI +Y+ RGH
Sbjct: 50 -----GDQPHSSVREQFLLLGRNSNRVQAVVQSSVSSDHERRQIGVLQLIAAYRNRGHQK 104
Query: 2625 ADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRL 2446
A LDPLG+ A +D P+L+LS +GL + DLD F + K TL E+++ +
Sbjct: 105 AKLDPLGL--AKREDV--PDLDLSAHGLTKSDLDTVF--NTSNLAIGKAEATLGEMVETM 158
Query: 2445 KDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVT-ELSHDQKKVLFKRLIRSTKFEEFLA 2269
+ IYC S G EYMH+ + +++ WI++R E R ++DQKK L +RL + E+FL
Sbjct: 159 ESIYCGSIGAEYMHIVDTKEKRWIQQRLEGARGQFNFTNDQKKALLERLTAAEGLEKFLG 218
Query: 2268 KKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATI 2089
K+ KRFG+EG E IP M ++I + ++G VIGMPHRGRLN+L N+ + A +
Sbjct: 219 NKYVGAKRFGVEGGESFIPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLLVNIMGKNPADL 278
Query: 2088 LSQFSTLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRA 1909
+F +GSGDVKYH G + + V +A+ NPSHLE V PVV G VRA
Sbjct: 279 FGEFEGKSIHKKGSGDVKYHQGFSSNVMTPGGE--VHLALAFNPSHLEIVGPVVEGSVRA 336
Query: 1908 EAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT 1729
D D + +++HGDAAFAGQGV ETF + YT G +HIV+NNQ+GFTT
Sbjct: 337 RQVRRKDIGGDDVLPVIVHGDAAFAGQGVNQETFQMSQTRGYTVGGTVHIVINNQVGFTT 396
Query: 1728 -DPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYR 1552
DPR +RS+ YCTDV ++V PIFHVN DDPEAV + +A D+R TF+KDV++DL CYR
Sbjct: 397 SDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEAVAFIAQLAHDFRHTFRKDVVIDLFCYR 456
Query: 1551 RHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDA 1372
R GHNE DEP TQPLMYQ I + T Y ++++ + V + + + Y S LE
Sbjct: 457 RRGHNEADEPSATQPLMYQVINKKPTTRTLYADQLVQQKVLDRAEADKLIEDYRSDLEAG 516
Query: 1371 YENAQKVTYVRNR----DWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGF 1204
A + N DW D+ D T + PEGF
Sbjct: 517 NHVANALVLEPNTKMFVDWKPYLGHDYTDVWD------TTIDINRLKELGEGMRKLPEGF 570
Query: 1203 NLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHH 1027
+ R + + + R +M + L+W E LA+ +L+ EG VR++G+DV RGTFSHRH
Sbjct: 571 VMQRQVSKVIDDRLKMQTGEMPLNWGAAETLAYATLIDEGYLVRITGEDVGRGTFSHRHA 630
Query: 1026 VLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFG 847
LH+Q VD Y PL + E Q + + +S LSE AVL FE GY+ PNSL+IWEAQFG
Sbjct: 631 KLHNQ-VDGSTYIPLCHVKENQPRFALYDSLLSEEAVLAFEYGYATTIPNSLIIWEAQFG 689
Query: 846 DFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI 667
DF+N AQ +IDQFI+SG++KW R GL MLLPHG+EG GPEHSSAR ERFLQ+C ED
Sbjct: 690 DFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFEGQGPEHSSARLERFLQLCAED--- 746
Query: 666 DLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHP 487
N V TTPA I+H LRRQ P RKP +V SPKSLLRH
Sbjct: 747 -------------------NMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHK 787
Query: 486 MARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVA 307
+A S +E+ +G+ FQ VI E +++ DV R+V C GKVYYD++ R+ + + N++A
Sbjct: 788 LATSTLEELATGT-FQTVIDEVDQITKS--DVTRLVLCGGKVYYDLIEKRREL-ELNNIA 843
Query: 306 LVRVEQLSPFPYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATK 130
+VR+EQL P+P + + Y +++W QEE KN GAW F+ PR+ + G+ +
Sbjct: 844 VVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILKSGKQIR 903
Query: 129 --YAGRLPSSSPATGNKFTHMQEQKEMMSKVFGV 34
YAGR S++PA G+ + H ++Q +++ +
Sbjct: 904 ISYAGREASAAPACGSPYLHAKQQAQLIHDALAI 937
>gi|46308512|ref|ZP_00210705.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Ehrlichia canis str. Jake]
Length = 912
Score = 692 bits (1785), Expect = 0.0
Identities = 395/911 (43%), Positives = 558/911 (60%), Gaps = 20/911 (2%)
Frame = -1
Query: 2715 LDTNASVQSISDH-LKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLG 2539
+D + SV I + KI L+ +++ GH +ADLDPL + + +L+ + Y
Sbjct: 50 IDQSNSVNIIDSYNSKILELLNFFRSYGHAVADLDPLKLQ-------VTGDLDYNKY--- 99
Query: 2538 ERDLDREFLLPPTTFISEK--KSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRR 2365
+D + P T F S + TL +++ LK IYC G E+MH+ N E++ W++ +
Sbjct: 100 ---IDLSEIKPSTKFNSVLGLDNPTLSDVIDTLKSIYCGKLGYEFMHIRNHEERLWLQNK 156
Query: 2364 FEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSS 2185
E+ ++S+D+KK + + L+ FE+FL ++P KRF +EG + L+ A++++ID S
Sbjct: 157 IESV-CNKISNDEKKEILQHLMEVECFEQFLHTRYPGYKRFSIEGGDSLVVAIEKIIDLS 215
Query: 2184 STLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS--TLEPAD-EGSGDVKYHLGVCI 2014
+ VIGM HRGRL+VL V ++P ++ +F T P D + SGDVKYHLG
Sbjct: 216 TVFNFREIVIGMSHRGRLSVLTKVMKKPYRAMIYEFKGGTAYPKDLDVSGDVKYHLGYSA 275
Query: 2013 ERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRT--MAILLHGDAA 1840
+R + K V +++ NPSHLE+V+PVVMGKVRA+ D CD+ + IL+HGDA+
Sbjct: 276 DR-QLSTDKIVHLSLCPNPSHLESVNPVVMGKVRAKQDVLQD--CDKPSIVGILVHGDAS 332
Query: 1839 FAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIF 1660
GQGVV ET L +L Y G IHI+VNNQIGFTT+P+ SRSS YC+D+ +++ P+F
Sbjct: 333 VIGQGVVAETLTLSNLTGYGICGVIHIIVNNQIGFTTNPKDSRSSFYCSDIAKLIDAPVF 392
Query: 1659 HVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQT 1480
HVN D PE ++ +A ++R+ F KDV++D+VCYRR+GHNE DEP+FTQP+MY I +
Sbjct: 393 HVNGDSPEDIVAAIKLAVEYRQKFNKDVVIDIVCYRRYGHNEGDEPLFTQPVMYDCITKH 452
Query: 1479 KTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYV-RNRDWLDSPWDDF 1303
KT ++ Y+E+++NE + E+ K T++ ++L + + ++K Y+ + DWL W +F
Sbjct: 453 KTPMKLYKEQLINENIITEEECKVLQTEFNNMLSEEFVQSEK--YIPKQADWLKGNWTNF 510
Query: 1302 FKKRDPLK------LPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKD-N 1144
R P+ L TG P+ FN ++ + + L R M+
Sbjct: 511 ---RRPVPGNFEDYLSDTGVDEQKLFKLAHALVNVPKEFNGNKKILKILSTRFDMVSSGE 567
Query: 1143 SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEG 964
++DWA GEALAF SLL E + VRLSGQD RGTFSHRH VL DQ V Y PLN+L
Sbjct: 568 NIDWATGEALAFASLLSENVRVRLSGQDCCRGTFSHRHAVLIDQ-VTGNSYVPLNNLGIP 626
Query: 963 QGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKW 784
Q + V NS LSEYAV+GFE GYS ++LV+WEAQFGDF+N AQ I+DQFISS ++KW
Sbjct: 627 QANFEVFNSPLSEYAVMGFEYGYSTDSTSTLVMWEAQFGDFANGAQIIVDQFISSAETKW 686
Query: 783 IRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNW 604
+R SGLV+LLPHGYEG GPEHSSAR ER+LQ+C ED N
Sbjct: 687 LRCSGLVLLLPHGYEGQGPEHSSARIERYLQLCAED----------------------NM 724
Query: 603 IVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPE 424
V NCTTPA+ +H+LRRQ+ FRKP V+F+PKSLLRH MA S + DF +F VI E
Sbjct: 725 QVVNCTTPASYFHVLRRQICRDFRKPLVIFTPKSLLRHKMAVSKLSDFT--GSFVPVIGE 782
Query: 423 TGAPSQNPPDVKRVVFCTGKVYYDMVAAR-KHVGKENDVALVRVEQLSPFPYDLVQQECR 247
S N V+RVV C+GKVY+D++ AR KH K +++A++R+EQ PFP D + E +
Sbjct: 783 VYPLSSN-DKVRRVVICSGKVYFDIIEARDKH--KIDNIAVIRLEQYYPFPEDQLANELK 839
Query: 246 KYQGAEILWAQEEHKNMGAWSFVQPRINSLL---SIDGRATKYAGRLPSSSPATGNKFTH 76
YQ AE++W QEE NMGAW FV + +L +I + R S++ A G H
Sbjct: 840 HYQNAEVVWCQEEPMNMGAWGFVNSYVERVLMKINIKSKRPLCVSRPASAATAAGYASMH 899
Query: 75 MQEQKEMMSKV 43
EQ +++S+V
Sbjct: 900 SNEQNDILSRV 910
>gi|48853408|ref|ZP_00307579.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Cytophaga hutchinsonii]
Length = 936
Score = 691 bits (1783), Expect = 0.0
Identities = 394/982 (40%), Positives = 569/982 (57%), Gaps = 8/982 (0%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+++ + Y+++MY+++ +DPSSV +W +F + G
Sbjct: 6 YVSNAEISYVDEMYQSYRKDPSSVDETWQKFFEGYNFSLQKYGEKGATNGGSAEAPSGNG 65
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDD 2581
AA +S+PAT + +++ LI +Y++RGH + +P+ + D
Sbjct: 66 VAAV----ASSPATTVSEK--------EVRVHYLIHAYRSRGHLRSKTNPV----RERKD 109
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
P LEL+ +GL + DLD F I + +LR+I++ LK IY + G EYM++
Sbjct: 110 R-KPLLELTDFGLTDADLDVVFEAGNEIGIG---AASLRKIVETLKFIYEGAIGFEYMYI 165
Query: 2400 NNLEQQDWIRRRFEAPRVTE-LSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCE 2224
E+ W+R + E + L+ D+KK + +L + FE FL K+ +KRF LEG E
Sbjct: 166 RKPEKLAWLRNKIEKESLAHNLTLDEKKRILSKLNEAVVFENFLHTKYVGQKRFSLEGGE 225
Query: 2223 VLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEP-ADEG 2050
IPA+ ++I +S+ LGV+ VIGM HRGRLNVLAN+ + I ++F ++P G
Sbjct: 226 TTIPALDKMITASAELGVEEVVIGMAHRGRLNVLANIMGKTYEQIFNEFEGNIKPDMTMG 285
Query: 2049 SGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEA--FYAGDEKCD 1876
GDVKYH+G E + + QK + + ++ NPSHLEAVDPVV+G VRA+ Y D K
Sbjct: 286 DGDVKYHMGYSSEVVTPKGQK-INLKLMPNPSHLEAVDPVVLGFVRAKGDRLYGYDYK-- 342
Query: 1875 RTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYC 1696
+ + +L+HGDAA A QG+V E + L Y T G IH V+NNQ+GFTTD +RSS YC
Sbjct: 343 KVLPVLIHGDAAVAAQGIVYEIVQMSKLAGYQTGGTIHFVINNQVGFTTDFEDARSSIYC 402
Query: 1695 TDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMF 1516
TDV ++V P+ HVN DDPEAV +AA++R+ F +D+ +D+VCYRRHGHNE DEP F
Sbjct: 403 TDVAKIVDAPVMHVNGDDPEAVTFCMRLAAEYRQKFNEDIFIDMVCYRRHGHNESDEPKF 462
Query: 1515 TQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRN 1336
TQP +Y I + E Y +K++ G + + K ++ +L+D ++ +
Sbjct: 463 TQPKLYNVISRHANPRELYNQKLIERGDVDAEIAKNMDREFRDMLQDRLNQVKQKPLPYS 522
Query: 1335 RDWLDSPWDDFFK--KRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQ 1162
++ W + K K D + P T + P F + +E+ LK R+
Sbjct: 523 LQKMEKEWTELRKATKEDFDQSPDTSITQEVIDKVGKAITDIPADFKPLKQIEKLLKDRK 582
Query: 1161 QMLKDNSL-DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNP 985
+ +D + +WA E LA+GSLL E VR SGQDVQRGTFSHRH VL D + ++ Y+
Sbjct: 583 EQFQDTKIVNWATAELLAYGSLLLEKKIVRFSGQDVQRGTFSHRHAVLKDAETNEPYYS- 641
Query: 984 LNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFI 805
LN +S+ Q + + NS LSEY VLGFE GY+M +P++LVIWEAQFGDF+N Q +IDQF+
Sbjct: 642 LNHISDNQKRFRIYNSLLSEYGVLGFEYGYAMANPSALVIWEAQFGDFANGTQVMIDQFV 701
Query: 804 SSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQ 625
+SG++KW RQ+GLVM LPHGYEG GPEHSSAR ERFL +C
Sbjct: 702 TSGETKWQRQNGLVMQLPHGYEGQGPEHSSARLERFLGLC-------------------- 741
Query: 624 QLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSN 445
+ N IV N TTPAN++H LRRQ+ FRKP + +PKSLLRHP+ S +++F SG
Sbjct: 742 --ANNNIIVTNITTPANMFHALRRQLKWEFRKPLINMAPKSLLRHPLVVSDLKEFTSG-R 798
Query: 444 FQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDL 265
FQ VI + ++ VKRV+FCTGKVYYD+ +K+ K NDVA+VR+EQL P+P
Sbjct: 799 FQEVIDDANVDAKK---VKRVLFCTGKVYYDLFEEQKN-AKRNDVAIVRIEQLYPYPEKQ 854
Query: 264 VQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNK 85
+ KY+GAE +W QEE NMGAW ++ + + ++ + R +SSPA G
Sbjct: 855 MAAVFEKYKGAEYVWVQEEPYNMGAWGYI---LRRMYLMNNTGIEVIARDEASSPAVGYL 911
Query: 84 FTHMQEQKEMMSKVFGVPKSKL 19
H ++Q E++ + F K+
Sbjct: 912 KAHNEKQAELVKRAFAEKIEKM 933
>gi|2499407|sp|Q59106|ODO1_ALCEU 2-oxoglutarate dehydrogenase E1
component (Alpha-ketoglutarate dehydrogenase)
gi|11252286|pir||T44422 oxoglutarate dehydrogenase (lipoamide) (EC
1.2.4.2) E1 chain [imported] - Ralstonia eutropha
gi|1279201|emb|CAA62980.1| oxoglutarate dehydrogenase (E1) [Ralstonia
eutropha]
gi|1588694|prf||2209294B 2-oxoglutarate dehydrogenase
Length = 950
Score = 689 bits (1779), Expect = 0.0
Identities = 413/995 (41%), Positives = 571/995 (56%), Gaps = 18/995 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L G ++ Y+E++YEA+LQ+P+SV +W AYF ++ G+ G
Sbjct: 10 YLFGGNAPYVEELYEAYLQNPASVPDNWRAYFDAMQNVPAVD------------GSNGRD 57
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISD------HLKIQLLIRSYQTRGHNIADLDPLGIN 2599
A + S A + ++ + +D + LI +Y+ G + ADLDPL
Sbjct: 58 IPHAPIVASFAERAKQGPIRTIVASADSDMGRKRVAATQLIAAYRNIGSHWADLDPL--- 114
Query: 2598 SADLDDTIP-PELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTST 2422
+ P P+L+ +FYG E DLD F T F K+S++LRE+L L++ YC +
Sbjct: 115 --KRQERPPLPDLDPAFYGFSEADLDIVFNASNTYF--GKESMSLRELLNNLRETYCGTI 170
Query: 2421 GVEYMHLNNLEQQDWIRRRFEAPRVTEL-SHDQKKVLFKRLIRSTKFEEFLAKKWPSEKR 2245
G E+M++++ Q+ W + R E R + + ++KK + RL + E FL K+ +KR
Sbjct: 171 GFEFMYVSDQAQKRWWQERLETTRSKPVFTLEKKKHILDRLTAAEGLERFLHTKYVGQKR 230
Query: 2244 FGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLE 2065
F LEG E I AM ++I + + GV VIGM HRGRLNVL N + A + ++F
Sbjct: 231 FSLEGGESFIAAMDELIQHAGSKGVQEIVIGMAHRGRLNVLVNTLGKMPADLFAEFEGKH 290
Query: 2064 PADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDE 1885
D +GDVKYH G + ++ +A NPSHLE V+PVV G +A G+
Sbjct: 291 VDDLPAGDVKYHKGFSSDVSTEGGPVHLSLAF--NPSHLEIVNPVVEGSAKARQERRGEV 348
Query: 1884 KCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRS 1708
+ + +HGDAAFAGQGVV+ET NL Y T G++HIV+NNQIGFTT DPR +RS
Sbjct: 349 GHKEVLPVQVHGDAAFAGQGVVMETLNLAQTRGYGTGGSMHIVINNQIGFTTSDPRDARS 408
Query: 1707 SPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELD 1528
+ YCTDV +++ P+ HVN DDPEAV++ +A D+R FKKDV+VD++C+R+ GHNE D
Sbjct: 409 TLYCTDVVKMIEAPVLHVNGDDPEAVVYAMQLAVDFRMEFKKDVVVDIICFRKLGHNEQD 468
Query: 1527 EPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKV- 1351
P TQPLMY++I Q + Y +K+ + + ++ E++ Y + ++ A V
Sbjct: 469 TPAVTQPLMYKKIAQHPGTRKLYADKLAAQNLVPAEFGDEKVKAYRAAMDAGKHTADPVL 528
Query: 1350 TYVRNR---DWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLER 1180
+ +N+ DW+ F R T + + PE LH +E+
Sbjct: 529 SNFKNKFAVDWMP------FLNRKWTDAADTAVPVTELKRLAERITTTPETLKLHPLVEK 582
Query: 1179 TLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQ--- 1012
+K R M + D LDW GE LAF SL+ G VR++ QD RGTF+HRH VLHDQ
Sbjct: 583 VVKDRANMGRGDQPLDWGMGEHLAFASLVSSGYPVRITAQDAGRGTFTHRHAVLHDQARE 642
Query: 1011 KVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNT 832
+ D Y PL ++SE Q +TV +S LSE AVLGFE GYS +PN+LVIWEAQFGDF N
Sbjct: 643 RWDAGSYVPLQNVSENQAPFTVIDSVLSEEAVLGFEYGYSAAEPNALVIWEAQFGDFVNG 702
Query: 831 AQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKI 652
AQ +IDQFISSG+ KW R SGL ++LPHGYEG GPEHSSAR ERFLQ+C
Sbjct: 703 AQVVIDQFISSGEVKWGRASGLTLMLPHGYEGQGPEHSSARIERFLQLC----------- 751
Query: 651 AFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSP 472
D N V TTPA I+HLLRRQ+ FRKP V+ +PKSLLR+ A SP
Sbjct: 752 -----------ADHNMQVCQPTTPAQIFHLLRRQMIRLFRKPLVIMTPKSLLRNKDAVSP 800
Query: 471 VEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVE 292
+ D G +F+ VIP+ N VKRV+ C+GKVYYD+V RK + ND A++R+E
Sbjct: 801 LSDLAKG-HFETVIPD--HEELNASKVKRVIMCSGKVYYDLVNTRKE-REANDTAVIRLE 856
Query: 291 QLSPFPYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRL 115
QL PFP+ V E +KY A EI+W Q+E +N GAW FVQ I ++ DG+ YAGR
Sbjct: 857 QLYPFPHKAVAAELKKYPNATEIVWCQDEPQNQGAWFFVQHYIMENMT-DGQKLGYAGRP 915
Query: 114 PSSSPATGNKFTHMQEQKEMMSKVFGVPKSKLEGF 10
S+SPA G H ++QK ++ F +KL+GF
Sbjct: 916 ASASPAVGYYAKHNEQQKALLEAAF----AKLKGF 946
>gi|26990881|ref|NP_746306.1| 2-oxoglutarate dehydrogenase, E1
component [Pseudomonas putida KT2440]
gi|24985894|gb|AAN69770.1| 2-oxoglutarate dehydrogenase, E1 component
[Pseudomonas putida KT2440]
Length = 943
Score = 689 bits (1778), Expect = 0.0
Identities = 404/993 (40%), Positives = 561/993 (55%), Gaps = 13/993 (1%)
Frame = -1
Query: 2973 QSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXX 2794
+SV + L+G ++ Y+E++YE +L DP++V W YF+ +
Sbjct: 3 ESVMQRMWDSAHLSGGNAAYVEELYELYLHDPNAVPEEWRTYFQKLPADGSTATDVSHST 62
Query: 2793 XXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLD 2614
+ L + AQ ++ + S + +++ LI++Y+ RGH A LD
Sbjct: 63 IRDHFVLLAKNQRRAQPVSAGS--------VSSEHEKKQVEVLRLIQAYRMRGHQAAKLD 114
Query: 2613 PLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIY 2434
PLG+ P +L ++ YGL DLD F FI K+ +LR+I L+ Y
Sbjct: 115 PLGL----WQRPAPVDLSINHYGLTNADLDTTFRAGDL-FIG-KEEASLRDIFDALQKTY 168
Query: 2433 CTSTGVEYMHLNNLEQQDWIRRRFEAPRVT-ELSHDQKKVLFKRLIRSTKFEEFLAKKWP 2257
C + G E+ H+ + EQ+ W ++R E+ R E S D + L +R+ E++L K+P
Sbjct: 169 CRTIGAEFTHIVDSEQRSWFQQRLESVRGRPEYSADVQAHLLERVTAGEGLEKYLGTKYP 228
Query: 2256 SEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQF 2077
KRFGLEG E LIP + ++I S + G VIGM HRGRLNVL N + + +F
Sbjct: 229 GTKRFGLEGGESLIPMLDEMIQRSGSYGAKEVVIGMAHRGRLNVLVNTFGKNPRELFDEF 288
Query: 2076 STLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFY 1897
+ + GSGDVKYH G + + V +A+ NPSHLE V PVV G VRA
Sbjct: 289 EGKKMNELGSGDVKYHQGFSSNVMTPGGE--VHLAMAFNPSHLEIVSPVVEGSVRARQDR 346
Query: 1896 AGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFT-TDPR 1720
D D+ + I +HGDAAFAGQGVV+ETF + + T G +HIV+NNQ+GFT ++P
Sbjct: 347 RNDTVGDKVVPISIHGDAAFAGQGVVMETFQMSQTRGFKTGGTVHIVINNQVGFTISNPL 406
Query: 1719 SSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGH 1540
+RS+ Y TDV +++ PI HVN DDPEAV+ V +A D+R FK+DV++DLVCYRR GH
Sbjct: 407 DARSTEYATDVAKMIQAPILHVNGDDPEAVLFVTQLAIDYRMQFKRDVVIDLVCYRRRGH 466
Query: 1539 NELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENA 1360
NE DEP TQPLMYQ+I + +T E Y E+++ G + + + ++ +Y + L++
Sbjct: 467 NEADEPNGTQPLMYQQISKQRTTRELYAEQLIQAGRIDAERAQAKIDEYRNALDNGLHVV 526
Query: 1359 QKVTYVRNR----DW---LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFN 1201
+ + NR DW L W R LK K + PEGF
Sbjct: 527 KSLVKEPNRELFVDWRPYLGHAWTARHDTRFDLK---------TLQDLSAKLLELPEGFV 577
Query: 1200 LHRGLERTLKGRQQMLKDN-SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHV 1024
+ R + + + RQ+M ++W E +A+ +L EG +R++GQD+ RGTFSHRH V
Sbjct: 578 VQRQVSKIYEDRQKMQAGGLPINWGYAETMAYATLQFEGHPIRMTGQDIGRGTFSHRHAV 637
Query: 1023 LHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGD 844
LH+QK D Y PL +L GQ + + +S LSE AVL FE GYS PN+LVIWEAQFGD
Sbjct: 638 LHNQK-DASTYIPLQNLFPGQPRFDLYDSFLSEEAVLAFEYGYSTTMPNALVIWEAQFGD 696
Query: 843 FSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEID 664
F+N AQ +IDQFI+SG+ KW R GL MLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 697 FANGAQVVIDQFITSGEHKWGRLCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEH---- 752
Query: 663 LEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPM 484
N V TTPA IYHLLRRQV P RKP VV +PKSLLRH +
Sbjct: 753 ------------------NIQVCVPTTPAQIYHLLRRQVIRPLRKPLVVLTPKSLLRHKL 794
Query: 483 ARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVAL 304
A S +ED GS FQ VIPE A +P V+R+V C+GKVYYD++ R+ G+E D+A+
Sbjct: 795 AISTLEDLAEGS-FQTVIPEIDA--IDPAKVERLVLCSGKVYYDLLEKRRAEGRE-DIAI 850
Query: 303 VRVEQLSPFPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLLSIDGRA--T 133
+R+EQL PFP D + + Y + +W QEE N GAW Q + +L +A
Sbjct: 851 LRIEQLYPFPEDDLVEILAPYTNLKHAVWCQEEPMNQGAWYSSQHHMRRILGRHNKALVL 910
Query: 132 KYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGV 34
+YAGR S++PA G H ++Q++++ F V
Sbjct: 911 EYAGRDASAAPACGYASKHAEQQEKLLQDAFTV 943
>gi|15642087|ref|NP_231719.1| 2-oxoglutarate dehydrogenase, E1
component [Vibrio cholerae O1 biovar eltor str. N16961]
gi|11252270|pir||B82121 2-oxoglutarate dehydrogenase, E1 component
VC2087 [imported] - Vibrio cholerae (strain N16961
serogroup O1)
gi|9656635|gb|AAF95233.1| 2-oxoglutarate dehydrogenase, E1 component
[Vibrio cholerae O1 biovar eltor str. N16961]
Length = 936
Score = 688 bits (1776), Expect = 0.0
Identities = 401/978 (41%), Positives = 544/978 (55%), Gaps = 16/978 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G+++ Y+E +YE +L DP V W F + Y L
Sbjct: 15 LAGANATYVEDLYELYLSDPDLVSEEWKRVFDGLPAHPTNVVEQPHSRVRDYFRRLAQET 74
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGI-NSADLDD 2581
V S + +K+ LI +Y+ RGH A LDPLG+ N ++
Sbjct: 75 KHYNVQVSDPEVD-----------AKQVKVLQLINAYRFRGHEAAKLDPLGLWNRPEV-- 121
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
EL SF+ L + D++ F + +F K ++ L++I Q L+ IYC S G EYMH+
Sbjct: 122 ---AELNPSFHNLTQEDMEETFNVG--SFAIGKDTMKLKDIYQSLQKIYCGSVGAEYMHI 176
Query: 2400 NNLEQQDWIRRRFEAPRVTEL-SHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCE 2224
+ EQ+ WI++R E T + S ++K+ + L + E +L K+P KRF LEG +
Sbjct: 177 TDTEQKRWIQQRLEPVVGTPVFSKEEKRTFLEELTAAEGLERYLGAKFPGAKRFSLEGGD 236
Query: 2223 VLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSG 2044
L+P K++I + G+ VIGM HRGRLN+L NV + + +F+ G+G
Sbjct: 237 ALVPMTKEMIRHAGASGMREVVIGMAHRGRLNMLVNVLGKKPQDLFDEFAGKHGEGWGTG 296
Query: 2043 DVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMA 1864
DVKYH G + +V +A+ NPSHLE V+PVVMG VRA GDE + +
Sbjct: 297 DVKYHQGFSADFATPGG--DVHLALAFNPSHLEIVNPVVMGSVRARQDRLGDEDGSKVLP 354
Query: 1863 ILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDV 1687
I +HGD+A AGQGVV ETFN+ + G + IVVNNQ+GFTT +PR +RS+ YCTD+
Sbjct: 355 ITIHGDSAIAGQGVVAETFNMSQARGFCVGGTVRIVVNNQVGFTTSNPRDTRSTMYCTDI 414
Query: 1686 GRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQP 1507
++V PIFHVN DDPEAV V +A D+R FK+DV++DLVCYRRHGHNE DEP TQP
Sbjct: 415 AKMVQAPIFHVNSDDPEAVAFVTRLALDYRNEFKRDVVIDLVCYRRHGHNEADEPNATQP 474
Query: 1506 LMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILED-----------AYENA 1360
LMYQ+IK+ T + Y + + G + + + + +Y L+ A +
Sbjct: 475 LMYQKIKKHPTPRKLYADVLTERGECDLETATQLVNEYRDALDHGEVVVKEWRPMAMHSV 534
Query: 1359 QKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLER 1180
Y+ DW PW+ + +L G + QYPE LH +E+
Sbjct: 535 DWSPYL-GHDW-HIPWNSEYAME---RLQDLGR----------RVCQYPESHVLHSRVEK 579
Query: 1179 TLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVD 1003
+ R M+ + LDW E LA+ +LL +G +R+SGQD RGTF HRH VLH+Q D
Sbjct: 580 IYQDRLSMISGEKMLDWGMAETLAYATLLDDGKRIRISGQDSGRGTFFHRHAVLHNQN-D 638
Query: 1002 QKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQC 823
Y PL+ + GQG + V +S LSE AVL FE GY+ +P+ L +WEAQFGDF+N AQ
Sbjct: 639 ASTYIPLSQIHAGQGPFEVFDSVLSEEAVLAFEYGYATAEPSGLTLWEAQFGDFANGAQV 698
Query: 822 IIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFE 643
+IDQFISSG+ KW R GL MLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 699 VIDQFISSGEQKWGRLCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEQ----------- 747
Query: 642 GTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVED 463
N V +TPA +YH++RRQV P R+P VV SPKSLLRHP+ S +ED
Sbjct: 748 -----------NMQVVVPSTPAQVYHMIRRQVVRPMRRPLVVMSPKSLLRHPLCVSSMED 796
Query: 462 FQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLS 283
G+ FQ I E A NP VKRVVFC+GKVYYD++ R+ ++ DVA+VR+EQL
Sbjct: 797 LAHGT-FQPAIGEIDA--LNPSQVKRVVFCSGKVYYDLLEQRR-ANEQQDVAIVRIEQLY 852
Query: 282 PFPYDLVQQECRKYQG-AEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSS 106
PFP + VQ Y + +W QEE +N GAW Q + + G KYAGR S+
Sbjct: 853 PFPLEEVQAAIANYTNVVDYVWCQEEPQNQGAWYSSQHNFRAAIPA-GADLKYAGRPASA 911
Query: 105 SPATGNKFTHMQEQKEMM 52
SPA G HM++QK ++
Sbjct: 912 SPAVGYMSVHMKQQKALI 929
>gi|37679216|ref|NP_933825.1| 2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component [Vibrio vulnificus YJ016]
gi|37197959|dbj|BAC93796.1| 2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component [Vibrio vulnificus YJ016]
Length = 941
Score = 687 bits (1772), Expect = 0.0
Identities = 391/983 (39%), Positives = 548/983 (54%), Gaps = 15/983 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G+++ Y+E +YE +L DP V W F + Y L
Sbjct: 15 LAGANATYVEDLYELYLSDPDLVSEEWKRVFEGLPKPTKEVAEQPHSRVRDYFRRL---- 70
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 2578
A + S + D +A +K+ LI +Y+ RGH A+LDPLG+
Sbjct: 71 -AQETKHYSVQVSDPDVDAK------QVKVLQLINAYRFRGHEAAELDPLGL----WQRP 119
Query: 2577 IPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLN 2398
EL+ +F+ L E D + F + +F ++++ L++I LK YC S G EYMH+
Sbjct: 120 TVAELDPAFHNLTEDDFEETFNVG--SFAVGQETMPLKDIYTALKKTYCGSIGAEYMHMT 177
Query: 2397 NLEQQDWIRRRFEAP-RVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEV 2221
+ EQ+ WI++R E+ D+K+ L + E +L K+P KRF LEG +
Sbjct: 178 DTEQKRWIQQRLESVVGQPSFDKDEKRTFLAELTAAEGLERYLGAKFPGAKRFSLEGGDA 237
Query: 2220 LIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGD 2041
+IP MK++I + G+ VIGM HRGRLN+L NV + + +F+ G+GD
Sbjct: 238 MIPMMKELIRHAGRSGMREVVIGMAHRGRLNMLVNVLGKKPQDLFDEFAGKHGESWGTGD 297
Query: 2040 VKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAI 1861
VKYH G + +V +A+ NPSHLE V+PVVMG VRA GD+ + + I
Sbjct: 298 VKYHQGFSADFATPGG--DVHLALAFNPSHLEIVNPVVMGSVRARQDRLGDDDGSKVLPI 355
Query: 1860 LLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDVG 1684
+HGD+A AGQGVV ETFN+ + G + +VVNNQ+GFTT +PR +RS+ YCTD+
Sbjct: 356 TIHGDSAIAGQGVVAETFNMSQARGFCVGGTVRVVVNNQVGFTTSNPRDTRSTMYCTDIA 415
Query: 1683 RVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPL 1504
++V PIFHVN DDPEAV V +A D+R FK+DV++DLVCYRRHGHNE DEP TQPL
Sbjct: 416 KMVQAPIFHVNADDPEAVAFVTRIALDYRNEFKRDVVIDLVCYRRHGHNEADEPNATQPL 475
Query: 1503 MYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILED-----------AYENAQ 1357
MYQ+IK+ T + Y + +++ + + + + +Y L+ A +
Sbjct: 476 MYQKIKKHPTPRKLYADVLIDRNECDIETATQMVNEYRDALDHGEVVVKEWRPMALHSVD 535
Query: 1356 KVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERT 1177
Y+ DW D+PW + + K+ ++L + QYPE LH + +
Sbjct: 536 WSPYL-GHDW-DTPWSNTYDKQRLVELGK-------------RLCQYPESHTLHSRVSKL 580
Query: 1176 LKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQ 1000
R M + LDW E LA+ +L+ +G +R+SGQD RGTF HRH VLH+Q D
Sbjct: 581 YNDRTAMTNGEKELDWGMAETLAYATLVDDGKRIRISGQDSGRGTFFHRHAVLHNQN-DA 639
Query: 999 KIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCI 820
Y PL ++ + QG + V +S LSE AVL FE GY+ +P+ L +WEAQFGDF+N AQ +
Sbjct: 640 STYVPLANIHDKQGPFEVFDSVLSEEAVLAFEYGYATAEPSGLTLWEAQFGDFANGAQVV 699
Query: 819 IDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEG 640
IDQFISSG+ KW R GL MLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 700 IDQFISSGEQKWARLCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEQ------------ 747
Query: 639 TFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDF 460
N V +TPA +YH++RRQV P R+P +V SPKSLLRHP+ S ++D
Sbjct: 748 ----------NMQVVVPSTPAQVYHMIRRQVVRPMRRPLIVMSPKSLLRHPLCTSSLDDL 797
Query: 459 QSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSP 280
+G+ F IPE +P VKRVVFC+GKVY+D++ R++ +++DVA+VR+EQL P
Sbjct: 798 ANGT-FMPAIPE--IDELDPAKVKRVVFCSGKVYFDLLEQRRN-NEQDDVAIVRIEQLYP 853
Query: 279 FPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSS 103
FP D V+ Y E +W QEE +N GAW Q + + G KYAGR S+S
Sbjct: 854 FPMDDVKAAIAPYVNVEDFVWCQEEPQNQGAWYCSQHNFRAAIPA-GTELKYAGRPASAS 912
Query: 102 PATGNKFTHMQEQKEMMSKVFGV 34
PA G H+++QK ++ V
Sbjct: 913 PAVGYMSVHLKQQKALIDDALNV 935
>gi|27363640|ref|NP_759168.1| 2-oxoglutarate dehydrogenase complex,
dehydrogenase component [Vibrio vulnificus CMCP6]
gi|27359756|gb|AAO08695.1| 2-oxoglutarate dehydrogenase complex,
dehydrogenase component [Vibrio vulnificus CMCP6]
Length = 941
Score = 687 bits (1772), Expect = 0.0
Identities = 389/981 (39%), Positives = 548/981 (55%), Gaps = 13/981 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G+++ Y+E +YE +L DP V W F + Y L
Sbjct: 15 LAGANATYVEDLYELYLSDPDLVSEEWKRVFEGLPKPTKEVAEQPHSRVRDYFRRL---- 70
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 2578
A + S + D +A +K+ LI +Y+ RGH A+LDPLG+
Sbjct: 71 -AQETKHYSVQVSDPDVDAK------QVKVLQLINAYRFRGHEAAELDPLGL----WQRP 119
Query: 2577 IPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLN 2398
EL+ +F+ L E D + F + +F ++++ L++I LK YC S G EYMH+
Sbjct: 120 TVAELDPAFHNLTEDDFEETFNVG--SFAVGQETMPLKDIYTALKKTYCGSIGAEYMHMT 177
Query: 2397 NLEQQDWIRRRFEAP-RVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEV 2221
+ EQ+ WI++R E+ D+K+ L + E +L K+P KRF LEG +
Sbjct: 178 DTEQKRWIQQRLESVVGQPSFDKDEKRTFLAELTAAEGLERYLGAKFPGAKRFSLEGGDA 237
Query: 2220 LIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGD 2041
+IP MK++I + G+ VIGM HRGRLN+L NV + + +F+ G+GD
Sbjct: 238 MIPMMKELIRHAGRSGMREVVIGMAHRGRLNMLVNVLGKKPQDLFDEFAGKHGESWGTGD 297
Query: 2040 VKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAI 1861
VKYH G + +V +A+ NPSHLE V+PVVMG VRA GD+ + + I
Sbjct: 298 VKYHQGFSADFATPGG--DVHLALAFNPSHLEIVNPVVMGSVRARQDRLGDDDGSKVLPI 355
Query: 1860 LLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDVG 1684
+HGD+A AGQGVV ETFN+ + G + +VVNNQ+GFTT +PR +RS+ YCTD+
Sbjct: 356 TIHGDSAIAGQGVVAETFNMSQARGFCVGGTVRVVVNNQVGFTTSNPRDTRSTMYCTDIA 415
Query: 1683 RVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPL 1504
++V PIFHVN DDPEAV V +A D+R FK+DV++DLVCYRRHGHNE DEP TQPL
Sbjct: 416 KMVQAPIFHVNADDPEAVAFVTRIALDYRNEFKRDVVIDLVCYRRHGHNEADEPNATQPL 475
Query: 1503 MYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILE--DAYENAQKVTYVRNRD 1330
MYQ+IK+ T + Y + +++ + + + + +Y L+ + + + + D
Sbjct: 476 MYQKIKKHPTPRKLYADVLIDRNECDIETATQMVNEYRDALDHGEVVVKEWRPMALHSVD 535
Query: 1329 WL-------DSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLK 1171
W D+PW + + K+ ++L + QYPE LH + +
Sbjct: 536 WSPYLGHEWDTPWSNTYDKQRLVELGK-------------RLCQYPESHTLHSRVSKLYN 582
Query: 1170 GRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKI 994
R M + LDW E LA+ +L+ +G +R+SGQD RGTF HRH VLH+Q D
Sbjct: 583 DRTAMTNGEKELDWGMAETLAYATLVDDGKRIRISGQDSGRGTFFHRHAVLHNQN-DAST 641
Query: 993 YNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIID 814
Y PL ++ + QG + V +S LSE AVL FE GY+ +P+ L +WEAQFGDF+N AQ +ID
Sbjct: 642 YVPLANIHDKQGPFEVFDSVLSEEAVLAFEYGYATAEPSGLTLWEAQFGDFANGAQVVID 701
Query: 813 QFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTF 634
QFISSG+ KW R GL MLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 702 QFISSGEQKWARLCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEQ-------------- 747
Query: 633 EAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQS 454
N V +TPA +YH++RRQV P R+P +V SPKSLLRHP+ S ++D +
Sbjct: 748 --------NMQVVVPSTPAQVYHMIRRQVVRPMRRPLIVMSPKSLLRHPLCTSSLDDLAN 799
Query: 453 GSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFP 274
G+ F IPE +P VKRVVFC+GKVY+D++ R++ +++DVA+VR+EQL PFP
Sbjct: 800 GT-FMPAIPE--IDELDPAKVKRVVFCSGKVYFDLLEQRRN-NEQDDVAIVRIEQLYPFP 855
Query: 273 YDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPA 97
D V+ Y E +W QEE +N GAW Q + + G KYAGR S+SPA
Sbjct: 856 MDDVKAAIAPYVNVEDFVWCQEEPQNQGAWYCSQHNFRAAIPA-GTELKYAGRPASASPA 914
Query: 96 TGNKFTHMQEQKEMMSKVFGV 34
G H+++QK ++ V
Sbjct: 915 VGYMSVHLKQQKALIDDALNV 935
>gi|23612809|ref|NP_704348.1| 2-oxoglutarate dehydrogenase e1
component, mitochondrial precursor, putative [Plasmodium
falciparum 3D7]
gi|23499087|emb|CAD51167.1| 2-oxoglutarate dehydrogenase e1
component, mitochondrial precursor, putative [Plasmodium
falciparum 3D7]
Length = 1038
Score = 686 bits (1770), Expect = 0.0
Identities = 389/1009 (38%), Positives = 571/1009 (56%), Gaps = 40/1009 (3%)
Frame = -1
Query: 2934 NGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPA 2755
N S + YIE Y+ W +D +++H SWD+ F Y + ++
Sbjct: 35 NPSMTSYIENTYKIWKEDRNNLHKSWDSLF----------SMYPHAEMDNYNNPIKINRK 84
Query: 2754 AAQVTTSSAPATRLDTN--------------ASVQSISDHLKIQLLIRSYQTRGHNIADL 2617
S+ L N ++I D +I LIR YQ +GH A++
Sbjct: 85 TDNYNNSNCFQDVLKNNNLRITYVNNEMLEKGKTENIYDLARIVQLIRWYQKKGHLYANI 144
Query: 2616 DPLGINSADLDDTI---PPELELSF--YGLGERDLDREFL--LPPTTFISEK--KSLTLR 2464
+PL + ++ P + ++S+ +G E DLD+EF LP + S K LR
Sbjct: 145 NPLPLPKEPPYSSVCYEPCKRKMSYVDFGFNEDDLDKEFFFDLPSISGFSSNGMKKCNLR 204
Query: 2463 EILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKF 2284
+L+RL++ YC + G EYMH+ N ++I +R E + E KK + + R+ F
Sbjct: 205 NLLKRLEETYCGTIGFEYMHITNENIVNYIIQRIEKDKKYEYDTKMKKRILEYTARAFIF 264
Query: 2283 EEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQ 2104
E ++A K+ + KRFG++GCE LI MK +I ++ L VDS ++ M HRGRLNVL NV +
Sbjct: 265 ENYMAAKFATTKRFGVDGCETLITGMKALIKRAAQLDVDSVLMSMSHRGRLNVLFNVLHK 324
Query: 2103 PLATILSQFSTLEPADEG----SGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVD 1936
PL ++S+F + +GDVKYHLGV I+ + SQ+ + + +V N SHLE+VD
Sbjct: 325 PLEQMMSEFRGKTGFSDNIWGNTGDVKYHLGVEIDYYDEDSQRYIHMGIVDNSSHLESVD 384
Query: 1935 PVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIV 1756
P++MG+ RA+ +Y D++ + + I +HGDA+ AGQG+ ETF + LPSY G IHIV
Sbjct: 385 PILMGQARAQQYYCNDKEKKKVLPITIHGDASIAGQGIAYETFQMSKLPSYNVGGTIHIV 444
Query: 1755 VNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDV 1576
VNNQIGFTT P +RS YCTD+ + + PI HVN DDPEAV +V +A D R F D
Sbjct: 445 VNNQIGFTTYPIDARSGKYCTDIAKCIDIPIIHVNADDPEAVTYVFELALDIRNKFNIDT 504
Query: 1575 IVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTK 1396
I+D+V YRR GHNELD P FT PL+Y I + K+ L+ Y +K+++E + + + ++ T+
Sbjct: 505 IIDIVGYRRFGHNELDMPKFTNPLLYDVIARHKSVLDIYSKKLIDENIISLKEFEDNKTE 564
Query: 1395 YGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQY 1216
+ E YE ++ +L W+ + TG K
Sbjct: 565 IFNFYEQVYEKSKSFVPTPKEKYLPQ-WEHMVTPQKFSPSRKTGVEKDVLINLGKKIFTL 623
Query: 1215 PEGFNLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFS 1039
E F H + + K R L+ ++D+ E LA+ +LL +G H RLSGQD QRGTFS
Sbjct: 624 RENFTAHPIITKLFKSRIDSLETGKNIDFGTAELLAYATLLSDGFHARLSGQDSQRGTFS 683
Query: 1038 HRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWE 859
HRH VLHDQ + + YN + L V NS LSEYA LG+E+GYS P++LVIWE
Sbjct: 684 HRHAVLHDQ-ITYESYNIFDSLKTPH-TIEVNNSLLSEYACLGYEIGYSYEHPDALVIWE 741
Query: 858 AQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNE 679
AQFGDF+N AQ +ID +I+SG++KW +QSG+VMLLPHGY+G GPEHSSAR ERFLQ+C
Sbjct: 742 AQFGDFANGAQVMIDNYIASGETKWNKQSGIVMLLPHGYDGQGPEHSSARIERFLQLC-- 799
Query: 678 DDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSL 499
DD D+ + E + Q H N V NC+ P+N +H LRRQ+ FRKP +V +PK +
Sbjct: 800 DDREDIATYSVEKDNKIIQQH--NMQVINCSKPSNFFHALRRQMHRSFRKPLIVITPKKM 857
Query: 498 LRHPMARSPVEDFQSGSNFQRVIP-ETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGK 322
L+ MA +E+F + + F +P E G ++ ++KR++ C+G+VYYD++ R + K
Sbjct: 858 LKMRMAFDKIENFLTNTEFLPYLPEEVGHKLKDKKEIKRIILCSGQVYYDLLNYR-YTNK 916
Query: 321 ENDVALVRVEQLSPFPYDLVQQECRKYQG-AEILWAQEEHKNMGAWSFVQPRINSLL--- 154
+DVA+ R+EQLSPFP+ + + + Y +I+WAQEEH NMG W +V RI + +
Sbjct: 917 IDDVAIARIEQLSPFPFKQIMNDLQTYPNLRDIIWAQEEHMNMGPWFYVSRRIEASIKQL 976
Query: 153 -------SIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGVPK 28
+I +Y+GR ++ + G+ H+ + E + F + K
Sbjct: 977 KKDKPKWNIQIPQVRYSGRDVYAAQSAGDLNLHLYQLDEFLVDAFNLDK 1025
>gi|46912669|emb|CAG19459.1| putative 2-oxoglutarate dehydrogenase, E1
component [Photobacterium profundum]
Length = 937
Score = 685 bits (1768), Expect = 0.0
Identities = 403/972 (41%), Positives = 545/972 (55%), Gaps = 10/972 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G+++ Y+E +YE +L DP V W F ++ Y L
Sbjct: 15 LAGANATYVEDLYELYLSDPELVDEQWQTVFGDLPVVNENVVEQPHSRVRDYFRRLAKE- 73
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 2578
T+ AT D + V+ + K+ LI +Y+ RGH A+LDPLG+ +
Sbjct: 74 ------TTHLSATVSDPDVDVKQV----KVLQLINAYRFRGHQHANLDPLGLWQQER--- 120
Query: 2577 IPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLN 2398
EL+ F+ L E D + F + +F ++++ L EI LK YC S G EYMH+
Sbjct: 121 -VLELDPGFHNLTEDDFNESFNVG--SFAVGQETMKLSEIYAALKKTYCGSIGAEYMHIT 177
Query: 2397 NLEQQDWIRRRFEAPRVT-ELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEV 2221
N +++ WI++R E+ T S D+K+ + L + E +L K+P KRF LEG +
Sbjct: 178 NTDEKRWIQQRLESVSSTGTFSKDEKQCFLEELTAAEGLERYLGAKFPGAKRFSLEGGDA 237
Query: 2220 LIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGD 2041
LIP MK++I + + GV V+GM HRGRLN+L NV + + +F+ G+GD
Sbjct: 238 LIPMMKELIRHAGSQGVREVVVGMAHRGRLNMLVNVLGKKPQDLFDEFAGKHGESWGTGD 297
Query: 2040 VKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAI 1861
VKYH G + +V +A+ NPSHLE V+PVV+G VRA GD + + I
Sbjct: 298 VKYHQGFSADFATPGG--DVHLALAFNPSHLEIVNPVVVGSVRARQDRLGDSDGSKVLPI 355
Query: 1860 LLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDVG 1684
LHGD+A AGQGVV ETFN+ Y G I IVVNNQIGFTT +P+ RS+ YCTD+
Sbjct: 356 TLHGDSAIAGQGVVAETFNMSQARGYRVGGTIRIVVNNQIGFTTSNPQDMRSTEYCTDIA 415
Query: 1683 RVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPL 1504
++V PIFHVN DDPEAV V +A D+R TFK+DV++DLVCYRRHGHNE DEP TQPL
Sbjct: 416 KMVQAPIFHVNADDPEAVAFVTRIAFDFRNTFKRDVVIDLVCYRRHGHNEADEPNATQPL 475
Query: 1503 MYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILE--DAYENAQKVTYVRNRD 1330
MYQ+IK+ T + Y + + + G + + +Y L+ + + + + D
Sbjct: 476 MYQKIKKHPTPRKIYADTLTDSGSFELETATSLVNEYRDALDRGECVVKEWRPMKLHSVD 535
Query: 1329 W---LDSPWD-DFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQ 1162
W L W D+ K + +L G + Q+PE L +++ R
Sbjct: 536 WAPYLGHDWTVDWASKVERERLQELGK----------RICQFPESHTLQGRVQKLYNDRL 585
Query: 1161 QMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNP 985
ML D +DW E LA+ +L+ +G +R++GQD RGTF HRH VLH+Q D Y P
Sbjct: 586 SMLAGDKLVDWGMAETLAYATLVDDGNRIRITGQDSGRGTFFHRHAVLHNQ-ADASTYVP 644
Query: 984 LNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFI 805
L +L + QG + V +S LSE AVL FE GY+ +P+ L IWEAQFGDF+N AQ +IDQFI
Sbjct: 645 LANLHDKQGPFEVIDSVLSEEAVLAFEYGYATAEPSGLTIWEAQFGDFANGAQVVIDQFI 704
Query: 804 SSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQ 625
SSG+ KW R GL MLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 705 SSGEQKWGRMCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEQ----------------- 747
Query: 624 QLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSN 445
N V +TPA +YH+LRRQV P R+P +V SPKSLLRHP+ S +ED G+
Sbjct: 748 -----NMQVIVPSTPAQVYHMLRRQVVRPMRRPMIVMSPKSLLRHPLCVSTMEDLAEGT- 801
Query: 444 FQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDL 265
FQ I E A +P VKRVVFC+GKVYYD++ R+ K DVA+VR+EQL PFP +
Sbjct: 802 FQPAIGEVDA--LDPTQVKRVVFCSGKVYYDLLEQRRKNDK-TDVAIVRIEQLYPFPKEN 858
Query: 264 VQQECRKYQG-AEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGN 88
V+ YQ + +W QEE +N GAW Q S L G YAGR S+SPA G
Sbjct: 859 VEATLADYQHVTDYVWCQEEPQNQGAWYSSQHNFRSALP-KGSDLNYAGRPASASPAVGY 917
Query: 87 KFTHMQEQKEMM 52
H+++QK ++
Sbjct: 918 MSVHLKQQKALV 929
>gi|48834500|ref|ZP_00291510.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Thermobifida fusca]
Length = 1214
Score = 684 bits (1766), Expect = 0.0
Identities = 397/890 (44%), Positives = 530/890 (58%), Gaps = 12/890 (1%)
Frame = -1
Query: 2673 KIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTF 2494
++Q LI +Y+ RGH +AD DPL + P+L++ +GL DLDREF PT
Sbjct: 369 RVQELIHAYRVRGHLMADTDPL-----EYKQRRHPDLDVLEHGLTLWDLDREF---PTGG 420
Query: 2493 ISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVL 2314
K + LREIL L+D YC + G+EYMH+ + E+++WI+ R E +LS +++ +
Sbjct: 421 FGGKPVMKLREILGILRDSYCRTVGIEYMHIQSPEEREWIQARVER-EPEKLSREEQLHI 479
Query: 2313 FKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGR 2134
K L + FE FL K+ +KRF LEG E LIP + VI ++ +D VIGM HRGR
Sbjct: 480 LKLLNSAEAFETFLQTKYVGQKRFSLEGGESLIPLLDGVITKAARAQLDEVVIGMAHRGR 539
Query: 2133 LNVLANVCRQPLATILSQFS-TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVAN 1960
LNVLAN+C + A I +F L+P GSGDVKYHLG +K + I++ AN
Sbjct: 540 LNVLANICGKSYAQIFGEFEGNLDPRSAHGSGDVKYHLGTEGTFTTITGEK-IAISLAAN 598
Query: 1959 PSHLEAVDPVVMGKVRAEAFYAGDEKCDRT-MAILLHGDAAFAGQGVVLETFNLDDLPSY 1783
PSHLE V+PV G VRA+ T + IL+HGDAAFAGQGVV ET NL L Y
Sbjct: 599 PSHLETVNPVAEGIVRAKQDILNKGATGFTVLPILIHGDAAFAGQGVVAETLNLSQLRGY 658
Query: 1782 TTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAAD 1603
T G IHI+VNNQ+GFTT P+ SRSS Y TDV R+V PIFHVN DDPEAV+ V +A
Sbjct: 659 RTGGTIHIIVNNQVGFTTSPKDSRSSVYATDVARMVQAPIFHVNGDDPEAVVRVARLAFA 718
Query: 1602 WRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANE 1423
+R+ F KDV++DLVCYRR GHNE D P FTQPLMY I ++ + Y E ++ G
Sbjct: 719 YRQEFNKDVVIDLVCYRRRGHNEADNPSFTQPLMYDIIDAKRSTRKLYTEALIGRGDITL 778
Query: 1422 QYVKEELTKYGSILEDAYENAQKV--------TYVRNRDWLDSPWDDFFKKRDPLKLPST 1267
+ +E L Y LE A+ ++ + ++ + ++P D T
Sbjct: 779 EEAEEALRDYQEQLERAFAETREAAKKPIEPGSVIKPEVFTEAPIDH--------SATPT 830
Query: 1266 GXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEG 1087
+PEGF +H L L+ R +M+++N++DWA E LAFGSLL +G
Sbjct: 831 AVSEEVIKRVAETQVTFPEGFTVHPRLLPQLQRRVRMVEENAIDWAMAETLAFGSLLIDG 890
Query: 1086 IHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGF 907
VRL GQD +RGTF RH VL D+K ++ Y PL G ++ V +S LSEYA LGF
Sbjct: 891 HPVRLVGQDSRRGTFGQRHAVLVDRKTGEE-YTPLKVFDRGTAKFHVHDSLLSEYAALGF 949
Query: 906 ELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGP 727
E GYS+ P++LV WEAQFGDF N AQ +ID++ISSG+ KW ++S + +LLPHGYEG GP
Sbjct: 950 EYGYSLERPDALVAWEAQFGDFVNGAQTVIDEYISSGEQKWGQKSSVTLLLPHGYEGQGP 1009
Query: 726 EHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQV 547
+HSSAR ERFLQ+C ++ N V TTPAN +HLLR QV
Sbjct: 1010 DHSSARIERFLQLCAQE----------------------NMTVTIPTTPANYFHLLRWQV 1047
Query: 546 TMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTG 367
P+R+P +VF+PKS+LRH A S V +F SGS F+ +IP+T + P DV+RV+ C G
Sbjct: 1048 KSPYRRPLIVFTPKSMLRHKAAVSAVSEFTSGS-FRPLIPDTSGIA--PEDVRRVILCAG 1104
Query: 366 KVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGA-EILWAQEEHKNMGA 190
K+YY++ AARK G ++ A++RVE+L P P D ++Q+ R + A E+LW QEE NMG
Sbjct: 1105 KIYYELDAARKRTGDQH-TAIIRVERLYPLPIDEIRQQLRSFPNAGEVLWVQEEPANMGP 1163
Query: 189 WSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVF 40
W FV L R R SSSPATG+ H EQ+ +++ VF
Sbjct: 1164 WPFVALVFAEQLD---RPFTRISRSASSSPATGSAKRHEVEQQALVNTVF 1210
>gi|16759675|ref|NP_455292.1| 2-oxoglutarate dehydrogenase E1
component [Salmonella enterica subsp. enterica serovar
Typhi str. CT18]
gi|29142552|ref|NP_805894.1| 2-oxoglutarate dehydrogenase E1
component [Salmonella enterica subsp. enterica serovar
Typhi Ty2]
gi|25284473|pir||AD0591 2-oxoglutarate dehydrogenase E1 component
[imported] - Salmonella enterica subsp. enterica serovar
Typhi (strain CT18)
gi|16501968|emb|CAD05198.1| 2-oxoglutarate dehydrogenase E1 component
[Salmonella enterica subsp. enterica serovar Typhi]
gi|29138183|gb|AAO69754.1| 2-oxoglutarate dehydrogenase E1 component
[Salmonella enterica subsp. enterica serovar Typhi Ty2]
Length = 933
Score = 684 bits (1764), Expect = 0.0
Identities = 404/982 (41%), Positives = 546/982 (55%), Gaps = 13/982 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L+GS+ +IEQ+YE +L DP SV +W F+ + +
Sbjct: 14 YLSGSNQSWIEQLYEDFLTDPDSVDANWRLTFQQLPGTGVKPDQLHSKTREYFRRQ---- 69
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGI----NSA 2593
A + S+ + DTN +K+ LI +Y+ RGH A+LDPLG+ A
Sbjct: 70 --ALAGSRHSSTISDPDTNVK------QVKVLQLINAYRFRGHQHANLDPLGLWKQERVA 121
Query: 2592 DLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVE 2413
DLD SF+ L E D F + +F S K+++ L E+L LK YC G E
Sbjct: 122 DLDP--------SFHDLTEADFQETFNVG--SFASGKETMKLGELLDALKQTYCGPIGAE 171
Query: 2412 YMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLE 2233
YMH+ + E++ WI++R E+ R S D+KK L + E +L K+P KRF LE
Sbjct: 172 YMHITSTEEKRWIQQRIESGRAA-FSADEKKRFLNELTAAEGLERYLGAKFPGAKRFSLE 230
Query: 2232 GCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADE 2053
G + LIP +K+++ + G V+GM HRGRLNVL NV + + +F+
Sbjct: 231 GGDALIPMLKEMVRHAGNSGTREVVLGMAHRGRLNVLINVLGKKPQDLFDEFAGKHKEHL 290
Query: 2052 GSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDR 1873
G+GDVKYH+G + V +A+ NPSHLE V PVVMG VRA + ++
Sbjct: 291 GTGDVKYHMGFSSDIETEGGL--VHLALAFNPSHLEIVSPVVMGSVRARLDRLDEPSSNK 348
Query: 1872 TMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYC 1696
+ I +HGDAA GQGVV ET N+ Y G + IV+NNQ+GFTT +P +RS+PYC
Sbjct: 349 VLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYC 408
Query: 1695 TDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMF 1516
TD+G++V PIFHVN DDPEAV V +A D+R TFK+DV +DLVCYRRHGHNE DEP
Sbjct: 409 TDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSA 468
Query: 1515 TQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRN 1336
TQPLMYQ+IK+ T + Y +K+ + VA + E + Y L DA E K N
Sbjct: 469 TQPLMYQKIKKHPTPRKIYADKLEADKVATLEDATEMVNLYRDAL-DAGECVVKEWRPMN 527
Query: 1335 RD------WLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTL 1174
+L+ WD+ + + +K + S PE + + +
Sbjct: 528 MHSFTWSPYLNHEWDEAYPNKVEMK---------RLQELAKRISTVPEAIEMQSRVAKIY 578
Query: 1173 KGRQQMLKDNSL-DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQK 997
RQ M L DW E LA+ +L+ EGI VRLSG+D RGTF HRH V+H+Q +
Sbjct: 579 GDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQ-TNGS 637
Query: 996 IYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCII 817
Y PL + GQG++ V +S LSE AVL FE GY+ +P +L IWEAQFGDF+N AQ +I
Sbjct: 638 TYTPLQHIHSGQGQFKVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVI 697
Query: 816 DQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGT 637
DQFISSG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 698 DQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQ------------- 744
Query: 636 FEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQ 457
N V +TPA +YH+LRRQ R+P VV SPKSLLRHP+A S +++
Sbjct: 745 ---------NMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSTLDELA 795
Query: 456 SGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPF 277
+GS FQ I E +P VKRVV C+GKVYYD++ R+ + DVA+VR+EQL PF
Sbjct: 796 NGS-FQPAIGE--IDELDPKAVKRVVMCSGKVYYDLLEQRRK-NDQKDVAIVRIEQLYPF 851
Query: 276 PYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSP 100
P+ VQ+ + Y + +W QEE N GAW Q ++ G A +YAGR S+SP
Sbjct: 852 PHKAVQEALQPYAHVHDFVWCQEEPLNQGAWYCSQHHFREVIPF-GAALRYAGRPASASP 910
Query: 99 ATGNKFTHMQEQKEMMSKVFGV 34
A G H ++Q+++++ V
Sbjct: 911 AVGYMSVHQKQQQDLVNDALNV 932
>gi|3219721|gb|AAC23516.1| alpha-ketoglutarate dehydrogenase; E1
[Pseudomonas putida]
Length = 943
Score = 684 bits (1764), Expect = 0.0
Identities = 402/992 (40%), Positives = 557/992 (55%), Gaps = 13/992 (1%)
Frame = -1
Query: 2970 SVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXX 2791
SV + L+G ++ Y+E++YE +L DP++V W YF+ +
Sbjct: 4 SVMQRMWESAHLSGGNAAYVEELYELYLHDPNAVPEEWRTYFQKLPADGSTATDVSHSTI 63
Query: 2790 XAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDP 2611
L + AQ ++ + S + +++ LI++Y+ RGH A LDP
Sbjct: 64 RDQFVLLAKNQRRAQPVSAGS--------VSSEHEKKQVEVLRLIQAYRMRGHQAAKLDP 115
Query: 2610 LGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYC 2431
LG+ P +L ++ YGL DLD F FI K+ +LREI + L+ YC
Sbjct: 116 LGL----WQRPAPVDLSINHYGLTNADLDTTFRAGDL-FIG-KEEASLREIFEALQKTYC 169
Query: 2430 TSTGVEYMHLNNLEQQDWIRRRFEAPRVT-ELSHDQKKVLFKRLIRSTKFEEFLAKKWPS 2254
+ G E+ H+ + EQ+ W ++R E+ R E S D + L +R+ E++L K+P
Sbjct: 170 RTIGAEFTHIVDSEQRSWFQQRLESVRGRPEFSADVQAHLLERVTAGEGLEKYLGTKYPG 229
Query: 2253 EKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS 2074
KRFGLEG E LIP + ++I S + G VIGM HRGRLNVL N + + +F
Sbjct: 230 TKRFGLEGGESLIPMLDEMIQRSGSYGTKEVVIGMAHRGRLNVLVNTFGKNPRELFDEFE 289
Query: 2073 TLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYA 1894
+ + GSGDVKYH G + + V +A+ NPSHLE V PVV G VRA
Sbjct: 290 GKKMNELGSGDVKYHQGFSSNVMTAGGE--VHLAMAFNPSHLEIVSPVVEGSVRARQDRR 347
Query: 1893 GDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFT-TDPRS 1717
D D+ + I +HGD AFAGQGVV+ETF + + T G +HIV+NNQ+GFT ++P
Sbjct: 348 NDTVGDKVLPISIHGDKAFAGQGVVMETFQMSQTRGFKTGGTVHIVINNQVGFTISNPLD 407
Query: 1716 SRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHN 1537
+RS+ Y TDV +++ PI HVN DDPEAV+ V + D+R FK+DV++DLVCYRR GHN
Sbjct: 408 ARSTEYATDVAKMIQAPILHVNGDDPEAVLFVTQLRIDYRMQFKRDVVIDLVCYRRRGHN 467
Query: 1536 ELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQ 1357
E DEP TQPLMYQ+I + +T E Y E ++ G + + + ++ +Y + L++ +
Sbjct: 468 EADEPNGTQPLMYQQISKQRTTRELYAEALIQAGRIDAERAQAKIDEYRNALDNGLHVVK 527
Query: 1356 KVTYVRNR----DW---LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNL 1198
+ NR DW L W R LK K + PEGF +
Sbjct: 528 SLVKEPNRELFVDWRPYLGHAWTARHDTRFDLK---------TLQDLSAKLLEIPEGFVV 578
Query: 1197 HRGLERTLKGRQQMLKDN-SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVL 1021
R + + + RQ+M ++W E +A+ +L EG +R++GQD+ RGTFSHRH VL
Sbjct: 579 QRQVAKIYEDRQKMQAGGLPINWGYAETMAYATLQFEGHPIRMTGQDIGRGTFSHRHAVL 638
Query: 1020 HDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDF 841
H+QK D Y PL +L GQ + + +S LSE AVL FE GYS PN+LVIWEAQFGDF
Sbjct: 639 HNQK-DASTYVPLKNLFPGQPMFELYDSFLSEEAVLAFEYGYSTTTPNALVIWEAQFGDF 697
Query: 840 SNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDL 661
+N AQ +IDQFI+SG+ KW R GL MLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 698 ANGAQVVIDQFITSGEHKWGRLCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEH----- 752
Query: 660 EKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMA 481
N V TTPA+IYHLLRRQV P RKP +V +PKSLLRH +A
Sbjct: 753 -----------------NIQVCVPTTPAHIYHLLRRQVIRPLRKPLIVLTPKSLLRHKLA 795
Query: 480 RSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALV 301
S +ED GS FQ VIPE + +P V+R+V C GKVYYD++ R+ G+E D+A+V
Sbjct: 796 VSTLEDLAEGS-FQTVIPE--IDTLDPAKVERLVLCGGKVYYDLLEKRRAEGRE-DIAIV 851
Query: 300 RVEQLSPFPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLLSIDGRA--TK 130
R+EQL PFP D + + Y + +W QEE N GAW Q + +L +A +
Sbjct: 852 RIEQLYPFPEDDLVEILAPYTNLKHAVWCQEEPMNQGAWYSSQHHMRRILGRLNKALVLE 911
Query: 129 YAGRLPSSSPATGNKFTHMQEQKEMMSKVFGV 34
YAGR S++PA G H ++Q++++ F V
Sbjct: 912 YAGRDASAAPACGYASKHAEQQEKLLQDAFTV 943
>gi|37525384|ref|NP_928728.1| 2-oxoglutarate dehydrogenase E1
component (Alpha-ketoglutarate dehydrogenase)
[Photorhabdus luminescens subsp. laumondii TTO1]
gi|36784811|emb|CAE13723.1| 2-oxoglutarate dehydrogenase E1 component
(Alpha-ketoglutarate dehydrogenase) [Photorhabdus
luminescens subsp. laumondii TTO1]
Length = 935
Score = 683 bits (1762), Expect = 0.0
Identities = 396/980 (40%), Positives = 557/980 (56%), Gaps = 11/980 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
FL GS+ Y+EQ+YE ++ DP+SV SW F+ + +G S
Sbjct: 14 FLAGSNQSYVEQIYEDYITDPNSVDASWREIFQQLP-------------NAGLSGEQLHS 60
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSI-SDHLKIQLLIRSYQTRGHNIADLDPLGINSADLD 2584
+ TR ++ S ++ + +K+ LI +++ RGH A+LDPLG+ D
Sbjct: 61 QTRDYFRRLAKDTTRYHSSVSDPAMDAKQVKVLQLINAFRFRGHQNANLDPLGLWKQD-- 118
Query: 2583 DTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMH 2404
P+L+ +F+ L E D F + +F K+++ L ++ + LK YC S G EYMH
Sbjct: 119 --SVPDLDPAFHNLTEADFAETFNV--GSFAIGKETMKLADLYEALKRTYCGSIGAEYMH 174
Query: 2403 LNNLEQQDWIRRRFEAPRV-TELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGC 2227
+ N E++ WI++R E+ V ++ S ++K L + E +L K+P KRF LEG
Sbjct: 175 ITNTEEKRWIQQRLESVTVSSQFSVEEKHRFLAELTAAEGLERYLGAKFPGAKRFSLEGG 234
Query: 2226 EVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGS 2047
+ LIP +K +I + V+GM HRGRLNVL N+ + A + +FS G+
Sbjct: 235 DALIPMLKDLIRHAGKHDTREVVLGMAHRGRLNVLVNILGKKPADLFDEFSGKHKEHLGT 294
Query: 2046 GDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTM 1867
GDVKYH G + ++ V +A+ NPSHLE V PVV+G VRA + + + +
Sbjct: 295 GDVKYHQGFSSDFATEGAK--VHLALAFNPSHLEIVSPVVIGSVRARRDRLDEGRSNMVL 352
Query: 1866 AILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTD 1690
I +HGDAA GQGVV ET N+ Y G I I++NNQIGFTT +P+ +RS+ YCTD
Sbjct: 353 PITIHGDAAVTGQGVVQETLNMSQARGYEVGGTIRIIINNQIGFTTSNPKDARSTQYCTD 412
Query: 1689 VGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQ 1510
+ ++V PIFHVN DDPEAV V +A D+R TFK DV++DLVCYRRHGHNE DEP TQ
Sbjct: 413 IIKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKCDVMIDLVCYRRHGHNEADEPSATQ 472
Query: 1509 PLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILE--DAYENAQKVTYVRN 1336
P+MYQ+IK+ T + Y +K++ E + + V E + Y L+ D + + + +
Sbjct: 473 PMMYQKIKKHPTPRKIYGDKLVAENLISVDDVTEIVNLYRDALDRGDCVVDEWRSMGLHS 532
Query: 1335 RDW---LDSPWD-DFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKG 1168
W L+ WD ++ K D +L G + S PE +H + +
Sbjct: 533 FTWEPYLNHEWDEEYLHKVDVKRLQDLGR----------RISSVPEEVTMHSRVAKIYND 582
Query: 1167 RQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIY 991
R +M D DW E L + +L+ EG+ VRLSG+D RGTF HRH V+H+Q + +Y
Sbjct: 583 RAEMANGDKLFDWGAAETLTYATLVDEGVPVRLSGEDAGRGTFFHRHAVIHNQ-ANGSVY 641
Query: 990 NPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQ 811
PL ++ GQG + V +S LSE AVL FE GY+ +P +L IWEAQFGDF+N AQ +IDQ
Sbjct: 642 VPLANVHNGQGAFNVWDSVLSEEAVLAFEYGYATTEPRALTIWEAQFGDFANGAQVVIDQ 701
Query: 810 FISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFE 631
FISSG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 702 FISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQ--------------- 746
Query: 630 AQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSG 451
N V +TPA +YH+LRRQ R+P +V SPKSLLRHP+A S +++ +G
Sbjct: 747 -------NMQVCVPSTPAQVYHMLRRQALRGMRRPLIVMSPKSLLRHPLAVSSLDELANG 799
Query: 450 SNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPY 271
FQ VI ET A +P +KRVV C+GKVYYD++ R+ ++ DVA+VR+EQL PFP+
Sbjct: 800 -KFQTVIGETDA--LDPKGIKRVVLCSGKVYYDLLEQRRK-NEQTDVAIVRIEQLYPFPH 855
Query: 270 DLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPAT 94
VQ +Y + +W QEE N GAW Q ++ G + +YAGR S+SPA
Sbjct: 856 QDVQSTLEQYAHVHDFVWCQEEPLNQGAWYCSQHNFREVIPF-GASLRYAGRPASASPAV 914
Query: 93 GNKFTHMQEQKEMMSKVFGV 34
G H Q+Q+E+++ V
Sbjct: 915 GYMSVHQQQQQELVNDALNV 934
>gi|16764106|ref|NP_459721.1| 2-oxoglutarate dehydrogenase [Salmonella
typhimurium LT2]
gi|16419246|gb|AAL19680.1| 2-oxoglutarate dehydrogenase decarboxylase
component [Salmonella typhimurium LT2]
Length = 933
Score = 682 bits (1761), Expect = 0.0
Identities = 404/982 (41%), Positives = 545/982 (55%), Gaps = 13/982 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L+GS+ +IEQ+YE +L DP SV +W F+ + +
Sbjct: 14 YLSGSNQSWIEQLYEDFLTDPDSVDANWRLTFQQLPGTGVKPDQLHSKTREYFRRQ---- 69
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGI----NSA 2593
A + S+ + DTN +K+ LI +Y+ RGH A+LDPLG+ A
Sbjct: 70 --ALAGSRHSSTISDPDTNVK------QVKVLQLINAYRFRGHQHANLDPLGLWKQERVA 121
Query: 2592 DLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVE 2413
DLD SF+ L E D F + +F S K+++ L E+L LK YC G E
Sbjct: 122 DLDP--------SFHDLTEADFQETFNVG--SFASGKETMKLGELLDALKQTYCGPIGAE 171
Query: 2412 YMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLE 2233
YMH+ + E++ WI++R E+ R S D+KK L + E +L K+P KRF LE
Sbjct: 172 YMHITSTEEKRWIQQRIESGRAA-FSADEKKRFLNELTAAEGLERYLGAKFPGAKRFSLE 230
Query: 2232 GCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADE 2053
G + LIP +K+++ + G V+GM HRGRLNVL NV + + +F+
Sbjct: 231 GGDALIPMLKEMVRHAGNSGTREVVLGMAHRGRLNVLINVLGKKPQDLFDEFAGKHKEHL 290
Query: 2052 GSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDR 1873
G+GDVKYH+G + V +A+ NPSHLE V PVVMG VRA + ++
Sbjct: 291 GTGDVKYHMGFSSDIETEGGL--VHLALAFNPSHLEIVSPVVMGSVRARLDRLDEPSSNK 348
Query: 1872 TMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYC 1696
+ I +HGDAA GQGVV ET N+ Y G + IV+NNQ+GFTT +P +RS+PYC
Sbjct: 349 VLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYC 408
Query: 1695 TDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMF 1516
TD+G++V PIFHVN DDPEAV V +A D+R TFK+DV +DLVCYRRHGHNE DEP
Sbjct: 409 TDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSA 468
Query: 1515 TQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRN 1336
TQPLMYQ+IK+ T + Y +K+ + VA + E + Y L DA E K N
Sbjct: 469 TQPLMYQKIKKHPTPRKIYADKLEADKVATLEDATEMVNLYRDAL-DAGECVVKEWRPMN 527
Query: 1335 RD------WLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTL 1174
+L+ WD+ + + +K + S PE + + +
Sbjct: 528 MHSFTWSPYLNHEWDEAYPNKVEMK---------RLQELAKRISTVPEAIEMQSRVAKIY 578
Query: 1173 KGRQQMLKDNSL-DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQK 997
RQ M L DW E LA+ +L+ EGI VRLSG+D RGTF HRH V+H+Q +
Sbjct: 579 GDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQ-TNGS 637
Query: 996 IYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCII 817
Y PL + GQG++ V +S LSE AVL FE GY+ +P +L IWEAQFGDF+N AQ +I
Sbjct: 638 TYTPLQHIHSGQGQFKVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVI 697
Query: 816 DQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGT 637
DQFISSG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 698 DQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQ------------- 744
Query: 636 FEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQ 457
N V +TPA +YH+LRRQ R+P VV SPKSLLRHP+A S +++
Sbjct: 745 ---------NMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSTLDELA 795
Query: 456 SGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPF 277
+GS FQ I E +P VKRVV C+GKVYYD++ R+ + DVA+VR+EQL PF
Sbjct: 796 NGS-FQPAIGE--IDELDPKAVKRVVMCSGKVYYDLLEQRRK-NDQKDVAIVRIEQLYPF 851
Query: 276 PYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSP 100
P+ VQ+ + Y + +W QEE N GAW Q + G A +YAGR S+SP
Sbjct: 852 PHKAVQEALQPYAHVHDFVWCQEEPLNQGAWYCSQHHFREVTPF-GAALRYAGRPASASP 910
Query: 99 ATGNKFTHMQEQKEMMSKVFGV 34
A G H ++Q+++++ V
Sbjct: 911 AVGYMSVHQKQQQDLVNDALNV 932
>gi|15830005|ref|NP_308778.1| 2-oxoglutarate dehydrogenase
decarboxylase component [Escherichia coli O157:H7]
gi|16128701|ref|NP_415254.1| 2-oxoglutarate dehydrogenase
(decarboxylase component); 2-oxoglutarate decarboxylase,
component of the 2-oxoglutarate dehydrogenase complex,
thiamin-binding [Escherichia coli K12]
gi|26246693|ref|NP_752733.1| 2-oxoglutarate dehydrogenase E1
component [Escherichia coli CFT073]
gi|2506963|sp|P07015|ODO1_ECOLI 2-oxoglutarate dehydrogenase E1
component (Alpha-ketoglutarate dehydrogenase)
gi|7427728|pir||DEECOG oxoglutarate dehydrogenase (lipoamide) (EC
1.2.4.2) - Escherichia coli (strain K-12)
gi|25284472|pir||G90722 oxoglutarate dehydrogenase (lipoamide) (EC
1.2.4.2) [similarity] - Escherichia coli (strain O157:H7,
substrain RIMD 0509952)
gi|1651321|dbj|BAA35392.1| Oxoglutarate dehydrogenase (lipoamide) (EC
1.2.4.2) [Escherichia coli K12]
gi|1786945|gb|AAC73820.1| 2-oxoglutarate dehydrogenase (decarboxylase
component); 2-oxoglutarate decarboxylase, component of
the 2-oxoglutarate dehydrogenase complex, thiamin-binding
[Escherichia coli K12]
gi|13360209|dbj|BAB34174.1| 2-oxoglutarate dehydrogenase
decarboxylase component [Escherichia coli O157:H7]
gi|26107092|gb|AAN79276.1| 2-oxoglutarate dehydrogenase E1 component
[Escherichia coli CFT073]
Length = 933
Score = 682 bits (1759), Expect = 0.0
Identities = 396/978 (40%), Positives = 552/978 (55%), Gaps = 9/978 (0%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L+G++ +IEQ+YE +L DP SV +W + F+ + +
Sbjct: 14 YLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHSQTREYFRRL--AK 71
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDD 2581
A+ +T S P DTN +K+ LI +Y+ RGH A+LDPLG+ D
Sbjct: 72 DASRYSSTISDP----DTNVK------QVKVLQLINAYRFRGHQHANLDPLGLWQQDKVA 121
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
+ P SF+ L E D F + +F S K+++ L E+L+ LK YC G EYMH+
Sbjct: 122 DLDP----SFHDLTEADFQETFNVG--SFASGKETMKLGELLEALKQTYCGPIGAEYMHI 175
Query: 2400 NNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEV 2221
+ E++ WI++R E+ R T S ++K+ L L + E +L K+P KRF LEG +
Sbjct: 176 TSTEEKRWIQQRIESGRATFNSEEKKRFL-SELTAAEGLERYLGAKFPGAKRFSLEGGDA 234
Query: 2220 LIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGD 2041
LIP +K++I + G V+GM HRGRLNVL NV + + +F+ G+GD
Sbjct: 235 LIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGD 294
Query: 2040 VKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAI 1861
VKYH+G + + V +A+ NPSHLE V PVV+G VRA + ++ + I
Sbjct: 295 VKYHMGFSSDF--QTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPI 352
Query: 1860 LLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDVG 1684
+HGDAA GQGVV ET N+ Y G + IV+NNQ+GFTT +P +RS+PYCTD+G
Sbjct: 353 TIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIG 412
Query: 1683 RVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPL 1504
++V PIFHVN DDPEAV V +A D+R TFK+DV +DLVCYRRHGHNE DEP TQPL
Sbjct: 413 KMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPL 472
Query: 1503 MYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILE--DAYENAQKVTYVRNRD 1330
MYQ+IK+ T + Y +K+ E VA + E + Y L+ D + + +
Sbjct: 473 MYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFT 532
Query: 1329 W---LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQ 1159
W L+ WD+ + + +K + S PE + + + RQ
Sbjct: 533 WSPYLNHEWDEEYPNKVEMK---------RLQELAKRISTVPEAVEMQSRVAKIYGDRQA 583
Query: 1158 MLKDNSL-DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPL 982
M L DW E LA+ +L+ EGI VRLSG+D RGTF HRH V+H+Q + Y PL
Sbjct: 584 MAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQS-NGSTYTPL 642
Query: 981 NDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFIS 802
+ GQG + V +S LSE AVL FE GY+ +P +L IWEAQFGDF+N AQ +IDQFIS
Sbjct: 643 QHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFIS 702
Query: 801 SGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQ 622
SG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 703 SGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQ------------------ 744
Query: 621 LHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNF 442
N V +TPA +YH+LRRQ R+P VV SPKSLLRHP+A S +E+ +G+
Sbjct: 745 ----NMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGT-- 798
Query: 441 QRVIPETGAPSQ-NPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDL 265
+P G + +P VKRVV C+GKVYYD++ R+ ++DVA+VR+EQL PFP+
Sbjct: 799 --FLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRK-NNQHDVAIVRIEQLYPFPHKA 855
Query: 264 VQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGN 88
+Q+ +++ + +W QEE N GAW Q ++ G + +YAGR S+SPA G
Sbjct: 856 MQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPF-GASLRYAGRPASASPAVGY 914
Query: 87 KFTHMQEQKEMMSKVFGV 34
H ++Q+++++ V
Sbjct: 915 MSVHQKQQQDLVNDALNV 932
>gi|28897621|ref|NP_797226.1| 2-oxoglutarate dehydrogenase, E1
component [Vibrio parahaemolyticus RIMD 2210633]
gi|28805833|dbj|BAC59110.1| 2-oxoglutarate dehydrogenase, E1
component [Vibrio parahaemolyticus]
Length = 941
Score = 682 bits (1759), Expect = 0.0
Identities = 391/983 (39%), Positives = 549/983 (55%), Gaps = 15/983 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G+++ Y+E +YE +L DP V W F + Y L
Sbjct: 15 LAGANATYVEDLYELYLSDPDLVSEEWKRVFEGLPKPSEEVAEQPHSRVRDYFRRLARET 74
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 2578
V S D +A +K+ LI +Y+ RGH A+LDPLG+
Sbjct: 75 KHYNVQVSDP-----DVDAK------QVKVLQLINAYRFRGHEAAELDPLGLWQR----- 118
Query: 2577 IPP--ELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMH 2404
PP EL+ +F+ L E D + F + +F ++++ L++I LK YC S G EYMH
Sbjct: 119 -PPVAELDPAFHNLTEDDFEETFNVG--SFAVGQETMKLKDIYAALKKTYCGSIGAEYMH 175
Query: 2403 LNNLEQQDWIRRRFEAP-RVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGC 2227
+ + EQ+ WI++R E+ + D+K+ + L + E +L K+P KRF LEG
Sbjct: 176 MTDTEQKRWIQQRLESVVGQPSFNQDEKRTFLEELTAAEGLERYLGAKFPGAKRFSLEGG 235
Query: 2226 EVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGS 2047
+ LIP K++I + G+ VIGM HRGRLN+L NV + + +F+ G+
Sbjct: 236 DALIPMTKELIRHAGKSGMREVVIGMAHRGRLNMLVNVLGKKPQDLFDEFAGKHDETWGT 295
Query: 2046 GDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTM 1867
GDVKYH G + +V +A+ NPSHLE V+PVV+G VRA GD + +
Sbjct: 296 GDVKYHQGFSADFATPGG--DVHLALAFNPSHLEIVNPVVIGSVRARQDRLGDNHGSKVL 353
Query: 1866 AILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTD 1690
I +HGD+A AGQGVV ETFN+ + G + IVVNNQ+GFTT +PR +RS+ YCTD
Sbjct: 354 PITIHGDSAIAGQGVVAETFNMSLARGFCVGGTVRIVVNNQVGFTTSNPRDTRSTMYCTD 413
Query: 1689 VGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQ 1510
+ ++V PIFHVN DDPEAV V +A D+R FK+DV++DLVCYRRHGHNE DEP TQ
Sbjct: 414 IAKMVQAPIFHVNADDPEAVAFVTRIALDYRNEFKRDVVIDLVCYRRHGHNEADEPNATQ 473
Query: 1509 PLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILE--DAYENAQKVTYVRN 1336
PLMYQ+IK+ T + Y + ++++ ++ + + + +Y L+ + + + +
Sbjct: 474 PLMYQKIKKHPTPRKLYADVLIDKNESDIETATQLVNEYRDALDRGEVVVKEWRPMALHS 533
Query: 1335 RDWL-------DSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERT 1177
DW D W+ + K+ ++L + + QYPE L + +
Sbjct: 534 VDWSPYLGHEWDMQWESTYDKQRLVELGN-------------RLCQYPESHKLQSRVNKL 580
Query: 1176 LKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQ 1000
R M+ + ++DW E LA+ +L+ +G +R+SGQD RGTF HRH VLH+Q D
Sbjct: 581 YNDRLAMMTGEKAIDWGMAETLAYATLVDDGKRIRISGQDSGRGTFFHRHSVLHNQS-DA 639
Query: 999 KIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCI 820
Y PL ++ + QG + V +S LSE AVL FE GY+ +P L IWEAQFGDF+N AQ +
Sbjct: 640 STYIPLANIHDKQGPFQVFDSVLSEEAVLAFEYGYATAEPGGLTIWEAQFGDFANGAQVV 699
Query: 819 IDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEG 640
IDQFISSG+ KW R GL MLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 700 IDQFISSGEQKWGRLCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEQ------------ 747
Query: 639 TFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDF 460
N V +TPA +YH++RRQV P R+P +V SPKSLLRHP+ S +ED
Sbjct: 748 ----------NMQVVVPSTPAQVYHMIRRQVVRPMRRPLIVMSPKSLLRHPLCTSTLEDL 797
Query: 459 QSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSP 280
G+ FQ IPE + P VKRVVFC+GKVY+D++ R++ ++ DVA+VR+EQL P
Sbjct: 798 AEGA-FQAAIPE--VDNLEPSKVKRVVFCSGKVYFDLLEQRRN-NEQEDVAIVRIEQLYP 853
Query: 279 FPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSS 103
FP + VQ +Y E +W QEE +N GAW Q + + G KYAGR S+S
Sbjct: 854 FPMEEVQAAIAQYTNVEDFVWCQEEPQNQGAWYCSQHNFRAAIPA-GADLKYAGRPASAS 912
Query: 102 PATGNKFTHMQEQKEMMSKVFGV 34
PA G H+++QK ++ V
Sbjct: 913 PAVGYMSVHLKQQKALVEDALNV 935
>gi|32041628|ref|ZP_00139211.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Pseudomonas aeruginosa UCBPP-PA14]
Length = 881
Score = 681 bits (1758), Expect = 0.0
Identities = 396/901 (43%), Positives = 527/901 (57%), Gaps = 17/901 (1%)
Frame = -1
Query: 2685 SDHLKIQL----LIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDRE 2518
S+H K Q+ LI +Y+ RGH + LDPLG+ P +L + YGL DLD
Sbjct: 25 SEHEKKQVEVLRLIHAYRLRGHQASTLDPLGL----WQRPAPADLSIDHYGLTGADLDTT 80
Query: 2517 FLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTE- 2341
F K+ TLREI+ LK YC + G E+MH+ + EQ+ W +R E+ R
Sbjct: 81 FRTGELYI--GKEEATLREIVDSLKSTYCGTFGAEFMHIVDSEQRKWFLQRLESVRGRPG 138
Query: 2340 LSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSF 2161
S + + L +RL + E++L K+P KRFGLEG E LIP + ++I + G
Sbjct: 139 FSAEARAHLLERLTAAEGLEKYLGTKYPGTKRFGLEGGESLIPMVDEIIQRCGSYGAKEI 198
Query: 2160 VIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVKYHLGVCIERLNRQSQKNV 1981
VIGM HRGRLNVL N + + +F + + GSGDVKYH G + S V
Sbjct: 199 VIGMAHRGRLNVLVNTLGKNPRDLFDEFEGKKIVELGSGDVKYHQGFSSNVMT--SGGEV 256
Query: 1980 KIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNL 1801
+A+ NPSHLE V PVV G VRA D D+ + I +HGDAAFAGQGVV+ETF +
Sbjct: 257 HLALAFNPSHLEIVSPVVEGSVRARQDRRKDSSGDKVVPISIHGDAAFAGQGVVMETFQM 316
Query: 1800 DDLPSYTTHGAIHIVVNNQIGFTTDPRS-SRSSPYCTDVGRVVGCPIFHVNVDDPEAVMH 1624
+Y T G IH+V+NNQ+GFTT + +RS+ Y TDV +++ PIFHVN DDPEAV+
Sbjct: 317 SQTRAYKTGGTIHLVINNQVGFTTSRQDDARSTEYATDVAKMIQAPIFHVNGDDPEAVLF 376
Query: 1623 VCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKIL 1444
V +A D+R FK+DV++DLVCYRR GHNE DEP TQPLMYQ+I + +T E Y + ++
Sbjct: 377 VTQLAVDYRMQFKRDVVIDLVCYRRRGHNEADEPSGTQPLMYQQIAKQRTTRELYADALV 436
Query: 1443 NEGVANEQYVKEELTKYGSILEDAY-------ENAQKVTYVRNRDWLDSPWDDFFKKRDP 1285
N GV + + V+ ++ Y L++ + K +V R +L W R
Sbjct: 437 NAGVLSAEQVQSKIDDYRDALDNGLHVVKSLVKEPNKELFVDWRPYLGHAWTARHDTRFD 496
Query: 1284 LKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKDN-SLDWACGEALAF 1108
LK K + PEGF + R + + + RQ+M ++W E LA+
Sbjct: 497 LK---------TLQELSSKMLEVPEGFVVQRQVSKIYEDRQKMAAGGLPINWGFAETLAY 547
Query: 1107 GSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLS 928
+LL EG VR++GQDV RGTFSHRH VLH+QK D +Y PL +L +GQ + +S LS
Sbjct: 548 ATLLFEGHPVRMTGQDVGRGTFSHRHAVLHNQK-DDSVYVPLANLFDGQPRLDIYDSFLS 606
Query: 927 EYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPH 748
E AVL FE G++ PNSLVIWEAQFGDF+N AQ +IDQFI+SG+SKW R GL MLLPH
Sbjct: 607 EEAVLAFEYGFATTTPNSLVIWEAQFGDFANGAQVVIDQFITSGESKWGRLCGLTMLLPH 666
Query: 747 GYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIY 568
GYEG GPEHSSAR ER+LQ+C E N V TTPA +Y
Sbjct: 667 GYEGQGPEHSSARLERYLQLCAEQ----------------------NIQVCVPTTPAQVY 704
Query: 567 HLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVK 388
H+LRRQV P RKP VV +PKSLLRH +A S +ED +GS FQ VIPE S +P V
Sbjct: 705 HMLRRQVIRPLRKPLVVMTPKSLLRHKLAISTLEDLANGS-FQTVIPE--IDSLDPKKVD 761
Query: 387 RVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAE-ILWAQE 211
RVV C+GKVYYD++ R+ G+E D A+VR+EQL PFP D + + Y+ + I+W QE
Sbjct: 762 RVVLCSGKVYYDLLEKRRAEGRE-DTAIVRIEQLYPFPEDDLAEVLAPYKNLKHIVWCQE 820
Query: 210 EHKNMGAWSFVQPRINSLLSI--DGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFG 37
E N GAW Q + +++ G +YAGR S++PA G H ++Q++++ F
Sbjct: 821 EPMNQGAWFCSQHHMRRVIAAHKKGLNLEYAGREGSAAPACGYASMHAEQQEKLLQDAFT 880
Query: 36 V 34
V
Sbjct: 881 V 881
>gi|24111998|ref|NP_706508.1| 2-oxoglutarate dehydrogenase
decarboxylase component [Shigella flexneri 2a str. 301]
gi|30062111|ref|NP_836282.1| 2-oxoglutarate dehydrogenase
(decarboxylase component) [Shigella flexneri 2a str.
2457T]
gi|24050814|gb|AAN42215.1| 2-oxoglutarate dehydrogenase decarboxylase
component [Shigella flexneri 2a str. 301]
gi|30040356|gb|AAP16088.1| 2-oxoglutarate dehydrogenase
(decarboxylase component) [Shigella flexneri 2a str.
2457T]
Length = 933
Score = 680 bits (1755), Expect = 0.0
Identities = 395/978 (40%), Positives = 551/978 (55%), Gaps = 9/978 (0%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L+G++ +IEQ+YE +L DP SV +W + F+ + +
Sbjct: 14 YLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHSQTREYFRRL--AK 71
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDD 2581
A+ +T S P DTN +K+ LI +Y+ RGH A+LDPLG+ D
Sbjct: 72 DASRYSSTISDP----DTNVK------QVKVLQLINAYRFRGHQHANLDPLGLWQQDKVA 121
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
+ P SF+ L E D F + +F S K+++ L E++ LK YC G EYMH+
Sbjct: 122 DLDP----SFHDLTEADFQETFNVG--SFASGKETMKLGELISALKQTYCGPIGAEYMHI 175
Query: 2400 NNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEV 2221
+ E++ WI++R E+ R T S ++K+ L L + E +L K+P KRF LEG +
Sbjct: 176 TSTEEKRWIQQRIESGRATFNSEEKKRFL-SELTAAEGLERYLGAKFPGAKRFSLEGGDA 234
Query: 2220 LIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGD 2041
LIP +K++I + G V+GM HRGRLNVL NV + + +F+ G+GD
Sbjct: 235 LIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGD 294
Query: 2040 VKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAI 1861
VKYH+G + + V +A+ NPSHLE V PVV+G VRA + ++ + I
Sbjct: 295 VKYHMGFSSDF--QTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPNSNKVLPI 352
Query: 1860 LLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDVG 1684
+HGDAA GQGVV ET N+ Y G + IV+NNQ+GFTT +P +RS+PYCTD+G
Sbjct: 353 TIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIG 412
Query: 1683 RVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPL 1504
++V PIFHVN DDPEAV V +A D+R TFK+DV +DLVCYRRHGHNE DEP TQPL
Sbjct: 413 KMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPL 472
Query: 1503 MYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILE--DAYENAQKVTYVRNRD 1330
MYQ+IK+ T + Y +K+ E VA + E + Y L+ D + + +
Sbjct: 473 MYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFT 532
Query: 1329 W---LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQ 1159
W L+ WD+ + + +K + S PE + + + RQ
Sbjct: 533 WSPYLNHEWDEEYPNKVEMK---------RLQELAKRISTVPEAVEMQSRVAKIYGDRQA 583
Query: 1158 MLKDNSL-DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPL 982
M L DW E LA+ +L+ EGI VRLSG+D RGTF HRH V+H+Q + Y PL
Sbjct: 584 MAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQS-NGSTYTPL 642
Query: 981 NDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFIS 802
+ GQG + V +S LSE AVL FE GY+ +P +L IWEAQFGDF+N AQ +IDQFIS
Sbjct: 643 QHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFIS 702
Query: 801 SGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQ 622
SG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 703 SGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQ------------------ 744
Query: 621 LHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNF 442
N V +TPA +YH+LRRQ R+P VV SPKSLLRHP+A S +E+ +G+
Sbjct: 745 ----NMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGT-- 798
Query: 441 QRVIPETGAPSQ-NPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDL 265
+P G + +P VKRVV C+GKVYYD++ R+ ++DVA+VR+EQL PFP+
Sbjct: 799 --FLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRK-NNQHDVAIVRIEQLYPFPHKA 855
Query: 264 VQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGN 88
+Q+ +++ + +W QEE N GAW Q ++ G + +YAGR S+SPA G
Sbjct: 856 MQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPF-GASLRYAGRPASASPAVGY 914
Query: 87 KFTHMQEQKEMMSKVFGV 34
H ++Q+++++ V
Sbjct: 915 MSVHQKQQQDLVNDALNV 932
>gi|15800430|ref|NP_286442.1| 2-oxoglutarate dehydrogenase
(decarboxylase component) [Escherichia coli O157:H7
EDL933]
gi|25284469|pir||F85573 hypothetical protein sucA [imported] -
Escherichia coli (strain O157:H7, substrain EDL933)
gi|12513641|gb|AAG55050.1| 2-oxoglutarate dehydrogenase
(decarboxylase component) [Escherichia coli O157:H7
EDL933]
Length = 933
Score = 680 bits (1754), Expect = 0.0
Identities = 395/978 (40%), Positives = 551/978 (55%), Gaps = 9/978 (0%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L+G++ +IEQ+YE +L DP SV +W + F+ + +
Sbjct: 14 YLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHSQTREYFRRL--AK 71
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDD 2581
A+ +T S P DTN +K+ I +Y+ RGH A+LDPLG+ D
Sbjct: 72 DASRYSSTISDP----DTNVK------QVKVLQXINAYRFRGHQHANLDPLGLWQQDKVA 121
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
+ P SF+ L E D F + +F S K+++ L E+L+ LK YC G EYMH+
Sbjct: 122 DLDP----SFHDLTEADFQETFNVG--SFASGKETMKLGELLEALKQTYCGPIGAEYMHI 175
Query: 2400 NNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEV 2221
+ E++ WI++R E+ R T S ++K+ L L + E +L K+P KRF LEG +
Sbjct: 176 TSTEEKRWIQQRIESGRATFNSEEKKRFL-SELTAAEGLERYLGAKFPGAKRFSLEGGDA 234
Query: 2220 LIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGD 2041
LIP +K++I + G V+GM HRGRLNVL NV + + +F+ G+GD
Sbjct: 235 LIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGD 294
Query: 2040 VKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAI 1861
VKYH+G + + V +A+ NPSHLE V PVV+G VRA + ++ + I
Sbjct: 295 VKYHMGFSSDF--QTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPI 352
Query: 1860 LLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDVG 1684
+HGDAA GQGVV ET N+ Y G + IV+NNQ+GFTT +P +RS+PYCTD+G
Sbjct: 353 TIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIG 412
Query: 1683 RVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPL 1504
++V PIFHVN DDPEAV V +A D+R TFK+DV +DLVCYRRHGHNE DEP TQPL
Sbjct: 413 KMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPL 472
Query: 1503 MYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILE--DAYENAQKVTYVRNRD 1330
MYQ+IK+ T + Y +K+ E VA + E + Y L+ D + + +
Sbjct: 473 MYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFT 532
Query: 1329 W---LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQ 1159
W L+ WD+ + + +K + S PE + + + RQ
Sbjct: 533 WSPYLNHEWDEEYPNKVEMK---------RLQELAKRISTVPEAVEMQSRVAKIYGDRQA 583
Query: 1158 MLKDNSL-DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPL 982
M L DW E LA+ +L+ EGI VRLSG+D RGTF HRH V+H+Q + Y PL
Sbjct: 584 MAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQS-NGSTYTPL 642
Query: 981 NDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFIS 802
+ GQG + V +S LSE AVL FE GY+ +P +L IWEAQFGDF+N AQ +IDQFIS
Sbjct: 643 QHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFIS 702
Query: 801 SGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQ 622
SG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 703 SGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQ------------------ 744
Query: 621 LHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNF 442
N V +TPA +YH+LRRQ R+P VV SPKSLLRHP+A S +E+ +G+
Sbjct: 745 ----NMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGT-- 798
Query: 441 QRVIPETGAPSQ-NPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDL 265
+P G + +P VKRVV C+GKVYYD++ R+ ++DVA+VR+EQL PFP+
Sbjct: 799 --FLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRK-NNQHDVAIVRIEQLYPFPHKA 855
Query: 264 VQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGN 88
+Q+ +++ + +W QEE N GAW Q ++ G + +YAGR S+SPA G
Sbjct: 856 MQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPF-GASLRYAGRPASASPAVGY 914
Query: 87 KFTHMQEQKEMMSKVFGV 34
H ++Q+++++ V
Sbjct: 915 MSVHQKQQQDLVNDALNV 932
>gi|48788280|ref|ZP_00284259.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Burkholderia fungorum LB400]
Length = 953
Score = 680 bits (1754), Expect = 0.0
Identities = 403/987 (40%), Positives = 563/987 (56%), Gaps = 15/987 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L G ++ Y+E+MYEA+L +P+SV +W +YF ++ +
Sbjct: 10 YLFGGNAPYVEEMYEAYLDNPASVPENWRSYFDALQNVPASDGSNANDVAHG-----PIV 64
Query: 2760 PAAAQVTTSSAPATR-LDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLD 2584
+ AQ ++A R + + + +Q LI +Y+ G A+LDPL +
Sbjct: 65 ESFAQRAKANAFIPRGAGGGEDLATARKQVYVQSLIGAYRFLGSQWANLDPLKRR----E 120
Query: 2583 DTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMH 2404
PELE +FY E D+D+EF F E+ SL REI++ L+D YC + G EYM+
Sbjct: 121 RPAIPELEPAFYDFTEADMDQEFSATNLYFGFERASL--REIVKALRDTYCGTIGAEYMY 178
Query: 2403 LNNLEQQDWIRRRFEAPRVT-ELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGC 2227
+++ EQ+ W + + E+ R T S+++KK + RL + E FL K+ +KRF LEG
Sbjct: 179 ISDPEQKRWWKEKLESIRSTPNFSNEKKKHILNRLTAAEGLERFLHTKYVGQKRFSLEGG 238
Query: 2226 EVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGS 2047
E I +M +V+ GV VIGM HRGRLNVL N + A + ++F D +
Sbjct: 239 ESFIASMDEVVRHGGANGVQEIVIGMAHRGRLNVLVNTLGKMPADLFAEFEGKHVDDLPA 298
Query: 2046 GDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTM 1867
GDVKYH G + ++ +A NPSHLE V+PVV G +A GD+ + +
Sbjct: 299 GDVKYHKGFSSDVSTEGGPVHLSLAF--NPSHLEIVNPVVEGSAKARMDRRGDDSGLQVL 356
Query: 1866 AILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTD 1690
+ +HGDAAFAGQGVV+ET NL Y THG +HIV+NNQIGFTT DPR SRS+ YC+D
Sbjct: 357 PVQIHGDAAFAGQGVVMETLNLAQTRGYGTHGTLHIVINNQIGFTTSDPRDSRSTLYCSD 416
Query: 1689 VGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQ 1510
V +++ P+ HVN DDPEAV+ +A D+R F KDV+VD+VC+R+ GHNE D P TQ
Sbjct: 417 VVKMIEAPVLHVNGDDPEAVVLATQLAIDFRMQFHKDVVVDIVCFRKLGHNEQDTPAVTQ 476
Query: 1509 PLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKV-TYVRNR 1333
PLMY+ I + Y EK++ +GV E + Y +++ + V + +++
Sbjct: 477 PLMYKTIAKHPGTRALYAEKLVQQGVITAADADEYVKAYRKAMDEGHHTVDPVLSNYKSK 536
Query: 1332 ---DW---LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLK 1171
DW L+ W D PL + + PE F +H +ER +
Sbjct: 537 YAVDWVPFLNRKWTDAADTAVPL---------AELKRLAERITTIPENFKVHPLVERVIN 587
Query: 1170 GRQQMLKDNS-LDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQ-- 1000
R+ M + + LDW GE LAF SL+ G VRL+GQD RGTF+HRH VLHDQ ++
Sbjct: 588 DRRAMGRGEAKLDWGMGEHLAFASLVASGYAVRLTGQDSGRGTFTHRHAVLHDQNRERWN 647
Query: 999 -KIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQC 823
Y PL +++EGQ ++TV +S LSE AVLGFE GYS +PN+ V WEAQFGDF N AQ
Sbjct: 648 DGTYVPLQNIAEGQAKFTVIDSVLSEEAVLGFEYGYSTAEPNTFVAWEAQFGDFVNGAQV 707
Query: 822 IIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFE 643
+IDQFISSG+ KW R SGL MLLPHGYEG GPEHSSAR ERFLQ+C
Sbjct: 708 VIDQFISSGEVKWGRVSGLTMLLPHGYEGQGPEHSSARIERFLQLC-------------- 753
Query: 642 GTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVED 463
D N V TTPA I+HLLRRQ+ FRKP +V +PKSLLRH A S + +
Sbjct: 754 --------ADHNMQVVQPTTPAQIFHLLRRQMIRLFRKPLIVATPKSLLRHKEAVSDLSE 805
Query: 462 FQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLS 283
G+ FQ ++ E + + VKRVV C+G+VYYD++A R+ K NDVA++R+EQL
Sbjct: 806 LAKGA-FQPILGEID-EAIDAKKVKRVVVCSGRVYYDLLAHRRE-SKSNDVAIIRIEQLY 862
Query: 282 PFPYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSS 106
PF + + E +KY A E++W Q+E +N G W +++ + + +G+ Y+GR S+
Sbjct: 863 PFAHKQFEAEMKKYDNATEVVWVQDEPQNQGPWFYIEHHLKDGMK-EGQKLAYSGRPASA 921
Query: 105 SPATGNKFTHMQEQKEMMSKVFGVPKS 25
SPA G H ++QK ++ FG KS
Sbjct: 922 SPAVGYYAKHYEQQKALVEGAFGRLKS 948
>gi|17545988|ref|NP_519390.1| PROBABLE OXOGLUTARATE DEHYDROGENASE
OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum GMI1000]
gi|17428283|emb|CAD14971.1| PROBABLE OXOGLUTARATE DEHYDROGENASE
OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum]
Length = 953
Score = 680 bits (1754), Expect = 0.0
Identities = 410/994 (41%), Positives = 567/994 (56%), Gaps = 17/994 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L+G ++ Y+E YEA+LQDP+SV + AYF ++ G+
Sbjct: 13 YLSGGNAAYVEDQYEAYLQDPTSVSEALRAYFDALQNIPAVD------------GSNARD 60
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISD------HLKIQLLIRSYQTRGHNIADLDPLGIN 2599
A A + TS A + ++ + +D + L+ +Y+ G ADLDPL
Sbjct: 61 IAHAPIVTSFAERAKQGPIKTIVASADSDMGRKRVSATQLVAAYRNVGLRWADLDPLKRQ 120
Query: 2598 SADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTG 2419
+ P+L+ +FYG E D D F T F K++++LRE+L L++ YC S G
Sbjct: 121 ----ERPPVPDLDPAFYGFTEADQDIVFNASNTYF--GKETMSLRELLNNLRETYCGSIG 174
Query: 2418 VEYMHLNNLEQQDWIRRRFEAPRVTE-LSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRF 2242
E+M++++ Q+ W + R E+ R S ++KK + +RL + E FL K+ +KRF
Sbjct: 175 AEFMYVSDQAQKRWWQERLESIRSKPTFSAEKKKHILERLTAAEGLERFLHTKYVGQKRF 234
Query: 2241 GLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEP 2062
LEG E I AM ++I + GV VIGM HRGRLNVL N + A + ++F
Sbjct: 235 SLEGGESFIAAMDELIQHAGEKGVQEIVIGMAHRGRLNVLVNTLGKMPADLFAEFEGKHV 294
Query: 2061 ADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEK 1882
D +GDVKYH G + ++ +A NPSHLE V+PVV G V+A GD+
Sbjct: 295 DDLPAGDVKYHKGFSSDVTTLGGPVHLSLAF--NPSHLEIVNPVVEGSVKARQERRGDKT 352
Query: 1881 CDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSS 1705
++ +A+ +HGDAAFAGQGVV+ET NL Y T G IHIV+NNQIGFTT DPR SRS+
Sbjct: 353 GEQVLAVQVHGDAAFAGQGVVMETLNLAQTRGYGTGGTIHIVINNQIGFTTSDPRDSRST 412
Query: 1704 PYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDE 1525
YCTDV +++ P+ HVN DDPEAV+ +A D+R FKKDV VD++C+R+ GHNE D
Sbjct: 413 LYCTDVVKMIEAPVLHVNGDDPEAVVLAMQLAIDFRTEFKKDVAVDIICFRKLGHNEQDT 472
Query: 1524 PMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKV-T 1348
P TQPLMY++I Q + Y +K++ + + + +Y + ++ V +
Sbjct: 473 PAMTQPLMYKKIGQHPGTRKLYADKLVTQSTLKTEEPDGLVQEYRAAMDAGKHTVDPVLS 532
Query: 1347 YVRNR---DWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERT 1177
+N+ DWL F R T + + P+ F +H +ER
Sbjct: 533 NFKNKFAVDWLP------FLNRKWTDSADTAVPMAELKRLAERITAIPDHFKVHPLVERV 586
Query: 1176 LKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQ---K 1009
+ R +M + + +LDW GE LAF SL+ G VR++GQD RGTF+HRH VLHDQ +
Sbjct: 587 VNDRAKMGQGEQALDWGMGEHLAFASLVASGYPVRITGQDAGRGTFTHRHAVLHDQNRER 646
Query: 1008 VDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTA 829
D Y PL ++S+ Q +TV +S LSE AV+GFE GYS +PN+LVIWEAQFGDF+N A
Sbjct: 647 WDAGSYIPLQNVSDNQAPFTVIDSVLSEEAVMGFEYGYSSAEPNTLVIWEAQFGDFANGA 706
Query: 828 QCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIA 649
Q +IDQFISSG+ KW R SGL ++LPHGYEG GPEHSSAR ER+LQ+C
Sbjct: 707 QVVIDQFISSGEVKWGRASGLTLMLPHGYEGQGPEHSSARMERYLQLC------------ 754
Query: 648 FEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPV 469
D N V TTPA I+HLLRRQ+ FRKP ++ +PKSLLR A SP+
Sbjct: 755 ----------ADHNMQVVQPTTPAQIFHLLRRQMIRLFRKPLIIMTPKSLLRSKDAVSPL 804
Query: 468 EDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQ 289
D G +F+ VI + N VKR+V C+GKVYYD+V ARK G D A++RVEQ
Sbjct: 805 TDLAKG-HFETVIAD--HEELNAAKVKRIVACSGKVYYDLVNARKERGL-TDTAIIRVEQ 860
Query: 288 LSPFPYDLVQQECRKYQG-AEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLP 112
L PFP+ E +KY AE++W Q+E +N GAW FVQ I +S +G+ YAGR
Sbjct: 861 LYPFPHKAFAAELKKYPNLAEVVWCQDEPQNQGAWFFVQHYIMENMS-EGQKLGYAGRPA 919
Query: 111 SSSPATGNKFTHMQEQKEMMSKVFGVPKSKLEGF 10
S+SPA G H ++QK ++ F +KL+GF
Sbjct: 920 SASPAVGYYAKHNEQQKALIDAAF----AKLKGF 949
>gi|21242286|ref|NP_641868.1| oxoglutarate dehydrogenase [Xanthomonas
axonopodis pv. citri str. 306]
gi|21107714|gb|AAM36404.1| oxoglutarate dehydrogenase [Xanthomonas
axonopodis pv. citri str. 306]
Length = 967
Score = 679 bits (1752), Expect = 0.0
Identities = 405/974 (41%), Positives = 557/974 (56%), Gaps = 11/974 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G ++ YIE +YE +L P SV W +YF E AG + S
Sbjct: 39 LAGGNAAYIEDLYEQYLVAPDSVDPKWKSYFDGFEGRG--------------AGDVPHSA 84
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 2578
A A + +S A T A + + LI +Y+ RGH A LDPLG+ +
Sbjct: 85 AIAHILAASKQAANAGTGAGASDERER-NVGRLITAYRARGHLGAQLDPLGL----VPPV 139
Query: 2577 IPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLN 2398
PP+L+L F+ L + DLD EF T + + + L+++L RLK Y +S G E+MH+
Sbjct: 140 NPPDLDLPFHSLSQADLDSEF---STGGVGGQPRMKLKDLLTRLKATYASSIGAEFMHIQ 196
Query: 2397 NLEQQDWIRRRFE--APRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCE 2224
+Q+ WI +R E ++ + +K+ L +RL + E +L K+ +KRF LEG +
Sbjct: 197 EFDQRQWIYKRLEDAGGKIAGDAASRKRTL-ERLTAAEGLERYLHTKYVGQKRFSLEGGD 255
Query: 2223 VLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEPADEG- 2050
LIP M ++I S V VIGM HRGRLNVL N + + +F E A +
Sbjct: 256 SLIPMMDEIIRQSGNDQVKDIVIGMAHRGRLNVLVNTLGKNPRKLFDEFEGKFEHAHDDR 315
Query: 2049 --SGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCD 1876
+GDVKYH+G + + + K V +A+ NPSHLE VDPVV+G VR+ GD +
Sbjct: 316 AHTGDVKYHMGFSAD-IAVGTDKQVHLALAFNPSHLEIVDPVVVGSVRSRQERFGDAERK 374
Query: 1875 RTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRS-SRSSPY 1699
+ IL+HGDAAFAGQGVV+E F + + G +HIVVNNQIGFTT R +RS+ Y
Sbjct: 375 SVLPILIHGDAAFAGQGVVMELFQMSQARGFAVGGTVHIVVNNQIGFTTSTRDDARSTLY 434
Query: 1698 CTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPM 1519
CTDV +++G P+FHVN DDP+AVM V +A ++R+ FKKDV++DLVCYRR GHNE DEP
Sbjct: 435 CTDVAKMIGAPVFHVNGDDPDAVMFVSKLAYEFRQQFKKDVVIDLVCYRRWGHNEADEPA 494
Query: 1518 FTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVR 1339
TQP+MYQ I++ KT E Y K+ +EGV + K + Y + L+ + R
Sbjct: 495 ATQPVMYQTIRKHKTTRELYAAKLESEGVLSADEAKALVDGYRNKLDSGEYTTELAK--R 552
Query: 1338 NRDWLDSPWDDFF--KKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGR 1165
D W + DP+ T + PEG LH + + + R
Sbjct: 553 KPDEFAIDWSRYLVGTAADPV---DTRVKRDQLDRLAKLITTIPEGVELHARVAKIYEDR 609
Query: 1164 QQMLKDNSL-DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYN 988
+M + L DW E LA+ +LL EG +RL GQD RGTF HRH +LHDQK D Y
Sbjct: 610 VKMAAGDQLGDWGFAENLAYATLLAEGHKLRLVGQDAGRGTFFHRHAILHDQKTDD-YYL 668
Query: 987 PLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQF 808
PL L + + TV +S LSE AV+GFE GYS DPN+L IWEAQFGDF+N AQ +IDQF
Sbjct: 669 PLRQLVQNPEDATVIDSLLSEEAVMGFEYGYSTTDPNALCIWEAQFGDFANGAQVVIDQF 728
Query: 807 ISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEA 628
I++G++KW R +GL + LPHGYEG GPEHSSAR ERFLQ+C A E
Sbjct: 729 IAAGEAKWGRIAGLSLFLPHGYEGQGPEHSSARLERFLQLC-----------ALE----- 772
Query: 627 QQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGS 448
N +V TTPA +H++RRQ+ M RKP VV +PKSLLRH +A S +E+ G
Sbjct: 773 ------NMLVCVPTTPAQCFHMIRRQMRMTTRKPLVVMTPKSLLRHKLAVSSLEELADG- 825
Query: 447 NFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYD 268
FQ +IP+ A + V+RVV C+GKVYYD++ + G ++DVA++RVEQL PFP
Sbjct: 826 QFQHLIPDAKADAAK---VRRVVLCSGKVYYDLLEDQTKRG-QDDVAILRVEQLYPFPRA 881
Query: 267 LVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATG 91
+ E + Y A +++W QEE +N GAW ++ +N L+ G++ YAGR S SPA G
Sbjct: 882 QLAAELKAYANATDVVWCQEEPQNQGAWYQIRHHLNFCLA-GGQSLHYAGRARSPSPAAG 940
Query: 90 NKFTHMQEQKEMMS 49
+ H+ EQ+++++
Sbjct: 941 HMADHIIEQQKLVA 954
>gi|43019|emb|CAA25280.1| unnamed protein product [Escherichia coli]
gi|146201|gb|AAA23897.1| 2-oxoglutarate dehydrogenase [Escherichia
coli K12]
Length = 933
Score = 678 bits (1749), Expect = 0.0
Identities = 395/978 (40%), Positives = 551/978 (55%), Gaps = 9/978 (0%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L+G++ +IEQ+YE +L DP SV +W + F+ + +
Sbjct: 14 YLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHSQTREYFRRL--AK 71
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDD 2581
A+ +T S P DTN +K+ LI +Y+ RGH A+LDPLG+ D
Sbjct: 72 DASRYSSTISDP----DTNVK------QVKVLQLINAYRFRGHQHANLDPLGLWQQDKVA 121
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
+ P SF+ L E D F + +F S K+++ L E+L+ LK YC G EYMH+
Sbjct: 122 DLDP----SFHDLTEADFQETFNVG--SFASGKETMKLGELLEALKQTYCGPIGAEYMHI 175
Query: 2400 NNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEV 2221
+ E++ WI++R E+ R T S ++K+ L L + E +L K+P KRF LEG +
Sbjct: 176 TSTEEKRWIQQRIESGRATFNSEEKKRFL-SELTAAEGLERYLGAKFPGAKRFSLEGGDA 234
Query: 2220 LIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGD 2041
LIP +K++I + G V+GM HRGRLNVL NV + + +F+ G+GD
Sbjct: 235 LIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGD 294
Query: 2040 VKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAI 1861
VKYH+G + + V +A+ NPSHLE V PVV+G VRA + ++ + I
Sbjct: 295 VKYHMGFSSDF--QTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPI 352
Query: 1860 LLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDVG 1684
+HGDAA GQGVV ET N+ Y G + IV+NNQ+GFTT +P +RS+PYCTD+G
Sbjct: 353 TIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIG 412
Query: 1683 RVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPL 1504
++V PIFHVN DDPEAV V +A D+R TFK+DV +DLV YRRHGHNE DEP TQPL
Sbjct: 413 KMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVSYRRHGHNEADEPSATQPL 472
Query: 1503 MYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILE--DAYENAQKVTYVRNRD 1330
MYQ+IK+ T + Y +K+ E VA + E + Y L+ D + + +
Sbjct: 473 MYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFT 532
Query: 1329 W---LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQ 1159
W L+ WD+ + + +K + S PE + + + RQ
Sbjct: 533 WSPYLNHEWDEEYPNKVEMK---------RLQELAKRISTVPEAVEMQSRVAKIYGDRQA 583
Query: 1158 MLKDNSL-DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPL 982
M L DW E LA+ +L+ EGI VRLSG+D RGTF HRH V+H+Q + Y PL
Sbjct: 584 MAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQS-NGSTYTPL 642
Query: 981 NDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFIS 802
+ GQG + V +S LSE AVL FE GY+ +P +L IWEAQFGDF+N AQ +IDQFIS
Sbjct: 643 QHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFIS 702
Query: 801 SGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQ 622
SG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 703 SGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQ------------------ 744
Query: 621 LHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNF 442
N V +TPA +YH+LRRQ R+P VV SPKSLLRHP+A S +E+ +G+
Sbjct: 745 ----NMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGT-- 798
Query: 441 QRVIPETGAPSQ-NPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDL 265
+P G + +P VKRVV C+GKVYYD++ R+ ++DVA+VR+EQL PFP+
Sbjct: 799 --FLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRK-NNQHDVAIVRIEQLYPFPHKA 855
Query: 264 VQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGN 88
+Q+ +++ + +W QEE N GAW Q ++ G + +YAGR S+SPA G
Sbjct: 856 MQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPF-GASLRYAGRPASASPAVGY 914
Query: 87 KFTHMQEQKEMMSKVFGV 34
H ++Q+++++ V
Sbjct: 915 MSVHQKQQQDLVNDALNV 932
>gi|23489985|gb|EAA21864.1| 2-oxoglutarate dehydrogenase, E1 component
[Plasmodium yoelii yoelii]
Length = 1038
Score = 674 bits (1739), Expect = 0.0
Identities = 380/1009 (37%), Positives = 567/1009 (55%), Gaps = 31/1009 (3%)
Frame = -1
Query: 2961 AAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAY 2782
++V + N S + Y+E +Y W D +++ SWD YF N+ Y
Sbjct: 28 SSVLYNEEFNPSMASYLENVYRLWKSDRNTLDKSWDRYFTNICNGMPNNSLLDENSRIIY 87
Query: 2781 AGA---LGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDP 2611
G ++T + ++ I+ +I LIR YQ GH A +P
Sbjct: 88 KNCDREYGERHNNLRITYVNEEMIEKGKTGNIYDIA---RIVQLIRWYQKNGHLYAQTNP 144
Query: 2610 LGI------NSADLDDTIPPELELSFYGLGERDLDREFL--LPPTTFISE--KKSLTLRE 2461
L + S + + ++ +G E DL +EF LP T S KK+ TL
Sbjct: 145 LPLPNVVPYTSINNGNNNEKKMTYKNFGFSEEDLKKEFSFDLPSITGFSSYGKKTCTLEC 204
Query: 2460 ILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFE 2281
++ +L++ YC + G EYMH+ + ++I +R E R S+ +KK + + R+ FE
Sbjct: 205 LINKLEETYCQTIGFEYMHITDENIVNYIIKRIENDRTYNFSNKEKKEILEFTARAFIFE 264
Query: 2280 EFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQP 2101
++A K+ + KRFG++GCE LI MK+++ + L +DS ++GM HRGRLNVL NV +P
Sbjct: 265 NYMAAKFATTKRFGVDGCETLITGMKELVKRACKLNIDSVLMGMSHRGRLNVLFNVLHKP 324
Query: 2100 LATILSQFSTLEPADEG----SGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDP 1933
L ++S+F + +GDVKYHLGV I+ + +S + + + +V N SHLE+VDP
Sbjct: 325 LEQMMSEFRGKTGFSDNVWGNTGDVKYHLGVEIDHYDEESNRYIHLGIVDNSSHLESVDP 384
Query: 1932 VVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVV 1753
++MG+ RA+ +Y D++ + + I++HGDA+ AGQG+ ETF + LPSY+ G IHIVV
Sbjct: 385 ILMGQARAQQYYCNDKEKKKVLPIIIHGDASIAGQGIAYETFQMSKLPSYSVGGTIHIVV 444
Query: 1752 NNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVI 1573
NNQIGFTT P +RS YCTD+G+ + PI HVN DDPEAV +V +A D R F D I
Sbjct: 445 NNQIGFTTYPVDARSGKYCTDIGKCIDIPIIHVNADDPEAVTYVFGLALDIRNKFNIDTI 504
Query: 1572 VDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKY 1393
+DLV YR+ GHNELD P FT PL+Y I + K+ L+ Y +K+++E V + +E K
Sbjct: 505 IDLVGYRKFGHNELDMPKFTNPLLYDVIARHKSVLDIYSKKLIDENVITLKEFEENTKKI 564
Query: 1392 GSILEDAYENAQKV-TYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQY 1216
E YE ++ + ++ +L W+ + TG K
Sbjct: 565 YDYYEQVYEQSKNFEPKIMDKKYLPQ-WEHMVNPQKFSPSRKTGVEKDVLINLGKKIFTI 623
Query: 1215 PEGFNLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFS 1039
E FN H + + K R L+ ++D+ E LA+ +LL +G H R+SGQD QRGTFS
Sbjct: 624 KENFNPHPIITKLFKTRIASLETGTNIDFGMAELLAYATLLSDGFHARISGQDSQRGTFS 683
Query: 1038 HRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWE 859
HRH VLHDQ + + YN + L V NS LSEYA LG+E+GYS P++LV+WE
Sbjct: 684 HRHAVLHDQ-ITYEEYNIFDSLKTPH-TIEVNNSLLSEYACLGYEIGYSYEHPDALVVWE 741
Query: 858 AQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNE 679
AQFGDF+N AQ +ID +I+SG++KW +QSG+VMLLPHGY+G GPEHSSAR ERFLQ+C
Sbjct: 742 AQFGDFANGAQVMIDNYIASGETKWNKQSGIVMLLPHGYDGQGPEHSSARIERFLQLC-- 799
Query: 678 DDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSL 499
DD D+ + + + Q H N V NCT P+N++H LRRQ+ FRKP +V +PK +
Sbjct: 800 DDREDIATYSIDKDKKIIQQH--NMQVINCTKPSNLFHALRRQMHRSFRKPLIVITPKKM 857
Query: 498 LRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPP-DVKRVVFCTGKVYYDMVAARKHVGK 322
L+ MA + +F + + F + E P ++KR++ C+G+VYYD++ R
Sbjct: 858 LKMRMAFDNINNFLTSTEFLPYLSEEFEHKLKPKNEIKRIILCSGQVYYDLLNYRDTNNI 917
Query: 321 ENDVALVRVEQLSPFPYDLVQQECRKYQG-AEILWAQEEHKNMGAWSFVQPRINSLL--- 154
+N +A+ R+EQLSPFP+ + + Y +++W QEEH NMG W +V RI + +
Sbjct: 918 QN-IAIARIEQLSPFPFKSFMNDLKNYPNLRDVIWVQEEHMNMGPWFYVSKRIEAAIKQL 976
Query: 153 -------SIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGVPK 28
+I+ Y+GR ++ + G+ H+ + E + F + K
Sbjct: 977 KNDDQSWNIEISEVYYSGRDVYAAQSAGDLNLHLYQLDEFLVDAFDLNK 1025
>gi|48844747|ref|ZP_00299046.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Geobacter metallireducens GS-15]
Length = 896
Score = 674 bits (1738), Expect = 0.0
Identities = 398/971 (40%), Positives = 540/971 (54%), Gaps = 4/971 (0%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G+ +IE +Y W DP++V T W A+F E G+
Sbjct: 4 LPGADPEFIESLYLRWRDDPAAVSTQWHAFFSGYELGR------------------GIPG 45
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 2578
A A +A + +D+ LI Y+ GH +A DPL +
Sbjct: 46 AEALPPKLAAKQSAVDS---------------LIYRYRDLGHLLACTDPLSPCKLE---- 86
Query: 2577 IPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLN 2398
P L L Y LGE DLDR F P F+ K+ TLREIL L++ YC S GVE+MH+
Sbjct: 87 -HPLLALDRYDLGEVDLDRTF--HPRRFL--KREATLREILATLRETYCRSVGVEFMHIQ 141
Query: 2397 NLEQQDWIRRRFEAPRVTE-LSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEV 2221
+ + W+ R E R S ++K + L + FEEFL +K+ +KRF LEG E
Sbjct: 142 DPAVRSWLMERMEPVRNRPAFSREEKLRILGTLQEAALFEEFLHRKFLGQKRFSLEGGET 201
Query: 2220 LIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEPADEGSG 2044
LIP + ++ ++ GV ++GM HRGRLNVLAN+ +PL I ++F+ E G G
Sbjct: 202 LIPLLDAAVERAAEHGVTDLILGMAHRGRLNVLANIFGKPLENIFAEFADNAELGIVGDG 261
Query: 2043 DVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMA 1864
DVKYH G +R +++ +A+ NPSHLEAVDPVV GK RA AG R +
Sbjct: 262 DVKYHKGFSHDR-EVAPGRSIHLAMAFNPSHLEAVDPVVEGKCRARQDSAGAGSDKRVLP 320
Query: 1863 ILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVG 1684
+L+HGDA+FAGQGVV ET NL L Y T G +HIV+NNQIGFTT P +RSS Y TDV
Sbjct: 321 VLIHGDASFAGQGVVAETLNLSQLEGYRTGGTLHIVINNQIGFTTLPADARSSLYATDVA 380
Query: 1683 RVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPL 1504
++V P+FHV+ +DPEA +HV +A D+R+ F DV+V+++CYRRHGHNE DEP FTQP
Sbjct: 381 KMVAAPVFHVHGEDPEAAVHVVRLALDYRQAFGGDVVVEIICYRRHGHNEGDEPYFTQPA 440
Query: 1503 MYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWL 1324
MY IK E Y ++ EG+ E+ + T G L+ A +
Sbjct: 441 MYSLIKDRPPVHELYAARLAEEGIGREE-IDARATAMGRRLDAALAAPPAPVH----GGF 495
Query: 1323 DSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLK-D 1147
+ W+ + + P+ + TG G+ + P+GF H + L R++ ++
Sbjct: 496 EGKWERYRRDYAPVSV-ETGVSPDILRNLAGRLAAIPDGFTPHPKVAALLNRRREAVEGG 554
Query: 1146 NSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSE 967
+DW E LA+ +LL +G+ +RLSG+D +RGTF HRH L+D D + PL ++
Sbjct: 555 EGIDWGNAETLAYATLLADGVSIRLSGEDSRRGTFGHRHSFLYDMATDAH-HVPLAGVAA 613
Query: 966 GQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSK 787
+ +S LSE+AVLGFE GYS+ P SLVIWEAQFGDF+N Q IIDQF++ G+SK
Sbjct: 614 EGAAFHGWDSMLSEFAVLGFEYGYSVEAPESLVIWEAQFGDFANGGQVIIDQFMAGGESK 673
Query: 786 WIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTN 607
W R SGLV+LLPHG+EG G EHSSAR ER+LQ+C D N
Sbjct: 674 WQRVSGLVLLLPHGFEGQGAEHSSARIERYLQLCG----------------------DNN 711
Query: 606 WIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIP 427
VA +TP ++HLLRRQ+ PFRKP VVF+PKSLLRHP S +E+ G F+ VI
Sbjct: 712 MQVAYPSTPGQLFHLLRRQMKHPFRKPLVVFTPKSLLRHPRCVSRLEELAEG-GFREVI- 769
Query: 426 ETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECR 247
TGA P R++ CTGK++YD++ R K DVA+VRVEQL P D +
Sbjct: 770 ATGA---GPDKASRLILCTGKIFYDLL-ERLEQEKREDVAIVRVEQLYPLRSDFLGGALE 825
Query: 246 KYQG-AEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQ 70
Y+G A++ W QEE +NMGAWSF++P + LL G +Y GR + PA G+ H +
Sbjct: 826 PYRGVADVAWVQEEPRNMGAWSFIRPHLAELL---GTEPRYVGRPENDVPAVGSHRLHGE 882
Query: 69 EQKEMMSKVFG 37
EQ ++ G
Sbjct: 883 EQGRIVEDALG 893
>gi|18149149|dbj|BAB83599.1| 2-oxoglutarate dehydrogenase [Pseudomonas
putida]
Length = 916
Score = 674 bits (1738), Expect = 0.0
Identities = 397/968 (41%), Positives = 546/968 (56%), Gaps = 13/968 (1%)
Frame = -1
Query: 2898 EAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVTTSSAPAT 2719
E +L DP++V W YF+ + + L + AQ ++ +
Sbjct: 1 ELYLHDPNAVPEEWRTYFQKLPADGSTATDVSHSTIRDHFVLLAKNQRRAQPVSAGS--- 57
Query: 2718 RLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLG 2539
S + +++ LI++Y+ RGH A LDPLG+ P +L ++ YGL
Sbjct: 58 -----VSSEHEKKQVEVLRLIQAYRMRGHQAAKLDPLGL----WQRPAPVDLSINHYGLT 108
Query: 2538 ERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFE 2359
DLD F FI K+ +LR+I L+ YC + G E+ H+ + EQ+ W ++R E
Sbjct: 109 NADLDTTFRAGDL-FIG-KEEASLRDIFDALQKTYCRTIGAEFTHIVDSEQRSWFQQRLE 166
Query: 2358 APRVT-ELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSS 2182
+ R E S D + L +R+ E++L K+P KRFGLEG E LIP + ++I S
Sbjct: 167 SVRGRPEYSADVQAHLLERVTAGEGLEKYLGTKYPGTKRFGLEGGESLIPMLDEMIQRSG 226
Query: 2181 TLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVKYHLGVCIERLN 2002
+ G VIGM HRGRLNVL N + + +F + + GSGDVKYH G +
Sbjct: 227 SYGAKEVVIGMAHRGRLNVLVNTFGKNPRELFDEFEGKKMNELGSGDVKYHQGFSSNVMT 286
Query: 2001 RQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGV 1822
+ V +A+ NPSHLE V PVV G VRA D D+ + I +HGDAAFAGQGV
Sbjct: 287 PGGE--VHLAMAFNPSHLEIVSPVVEGSVRARQDRRNDTVGDKVVPISIHGDAAFAGQGV 344
Query: 1821 VLETFNLDDLPSYTTHGAIHIVVNNQIGFT-TDPRSSRSSPYCTDVGRVVGCPIFHVNVD 1645
V+ETF + + T G +HIV+NNQ+GFT ++P +RS+ Y TDV +++ PI HVN D
Sbjct: 345 VMETFQMSQTRGFKTGGTVHIVINNQVGFTISNPLDARSTEYATDVAKMIQAPILHVNGD 404
Query: 1644 DPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALE 1465
DPEAV+ V +A D+R FK+DV++DLVCYRR GHNE DEP TQPLMYQ+I + +T E
Sbjct: 405 DPEAVLFVTQLAIDYRMQFKRDVVIDLVCYRRRGHNEADEPNGTQPLMYQQISKQRTTRE 464
Query: 1464 KYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNR----DW---LDSPWDD 1306
Y E+++ G + + + ++ +Y + L++ + + NR DW L W
Sbjct: 465 LYAEQLIQAGRIDAERAQAKIDEYRNALDNGLHVVKSLVKEPNRELFVDWRPYLGHAWTA 524
Query: 1305 FFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKDN-SLDWA 1129
R LK K + PEGF + R + + + RQ+M ++W
Sbjct: 525 RHDTRFDLK---------TLQDLSAKLLELPEGFVVQRQVSKIYEDRQKMQAGGLPINWG 575
Query: 1128 CGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYT 949
E +A+ +L EG +R++GQD+ RGTFSHRH VLH+QK D Y PL +L GQ +
Sbjct: 576 YAETMAYATLQFEGHPIRMTGQDIGRGTFSHRHAVLHNQK-DASTYIPLQNLFPGQPRFD 634
Query: 948 VCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSG 769
+ +S LSE AVL FE GYS PN+LVIWEAQFGDF+N AQ +IDQFI+SG+ KW R G
Sbjct: 635 LYDSFLSEEAVLAFEYGYSTTMPNALVIWEAQFGDFANGAQVVIDQFITSGEHKWGRLCG 694
Query: 768 LVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANC 589
L MLLPHGYEG GPEHSSAR ER+LQ+C E N V
Sbjct: 695 LTMLLPHGYEGQGPEHSSARLERYLQLCAEH----------------------NIQVCVP 732
Query: 588 TTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPS 409
TTPA IYHLLRRQV P RKP VV +PKSLLRH +A S +ED GS FQ VIPE A
Sbjct: 733 TTPAQIYHLLRRQVIRPLRKPLVVLTPKSLLRHKLAISTLEDLAEGS-FQTVIPEIDA-- 789
Query: 408 QNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAE 229
+P V+R+V C+GKVYYD++ R+ G+E D+A++R+EQL PFP D + + Y +
Sbjct: 790 IDPAKVERLVLCSGKVYYDLLEKRRAEGRE-DIAILRIEQLYPFPEDDLVEILAPYTNLK 848
Query: 228 -ILWAQEEHKNMGAWSFVQPRINSLLSIDGRA--TKYAGRLPSSSPATGNKFTHMQEQKE 58
+W QEE N GAW Q + +L +A +YAGR S++PA G H ++Q++
Sbjct: 849 HAVWCQEEPMNQGAWYSSQHHMRRILGRHNKALVLEYAGRDASAAPACGYASKHAEQQEK 908
Query: 57 MMSKVFGV 34
++ F V
Sbjct: 909 LLQDAFTV 916
>gi|21230942|ref|NP_636859.1| oxoglutarate dehydrogenase [Xanthomonas
campestris pv. campestris str. ATCC 33913]
gi|21112558|gb|AAM40783.1| oxoglutarate dehydrogenase [Xanthomonas
campestris pv. campestris str. ATCC 33913]
Length = 990
Score = 673 bits (1736), Expect = 0.0
Identities = 400/974 (41%), Positives = 552/974 (56%), Gaps = 11/974 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G ++ YIE +YE +L P SV W AYF AG + S
Sbjct: 62 LAGGNAAYIEDLYEQYLVAPDSVDPKWKAYFDGFNGRD--------------AGDVPHSA 107
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 2578
A A + ++S A T + + LI +Y++RGH A LDPLG+
Sbjct: 108 AIAHILSASKQAANAGTGVGASDERER-NVGRLITAYRSRGHLGAQLDPLGLTPP----V 162
Query: 2577 IPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLN 2398
PP+L+L F+ L + DLD EF T + + + L+++L RLK Y ++ G E+MH+
Sbjct: 163 NPPDLDLPFHSLSQADLDSEF---STGGVGGQPRMKLKDLLARLKATYASTIGAEFMHIP 219
Query: 2397 NLEQQDWIRRRFE--APRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCE 2224
+Q+ WI +R E ++ + +K+ L +RL + E +L K+ +KRF LEG +
Sbjct: 220 EFDQRQWIYKRLEDAGGKIAADAASRKRTL-ERLTAAEGLERYLHTKYVGQKRFSLEGGD 278
Query: 2223 VLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEPADEG- 2050
LIP M +I S V VIGM HRGRLNVL N + + +F E A +
Sbjct: 279 ALIPMMDTIIRQSGNDQVKDIVIGMAHRGRLNVLVNTLGKNPRKLFDEFEGKFEHAHDDR 338
Query: 2049 --SGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCD 1876
+GDVKYH+G + + K V +A+ NPSHLE VDPVV+G VR+ GD
Sbjct: 339 AHTGDVKYHMGFSAD-IAVGDDKQVHLALAFNPSHLEIVDPVVVGSVRSRQERFGDADRK 397
Query: 1875 RTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRS-SRSSPY 1699
+ IL+HGDAAFAGQGVV+E F + + G +HIVVNNQIGFTT R +RS+ Y
Sbjct: 398 TVLPILIHGDAAFAGQGVVMELFQMSQARGFAVGGTVHIVVNNQIGFTTSARDDARSTLY 457
Query: 1698 CTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPM 1519
CTDV +++G P+FHVN DDP+AVM V +A ++R+ FKKDV++DLVCYRR GHNE DEP
Sbjct: 458 CTDVAKMIGAPVFHVNGDDPDAVMFVSKLAYEFRQQFKKDVVIDLVCYRRWGHNEADEPA 517
Query: 1518 FTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVR 1339
TQP+MYQ I++ KT E Y K+ ++GV + K + Y + L+ + R
Sbjct: 518 ATQPVMYQTIRKHKTTRELYATKLESDGVLSADEAKALVDGYRNKLDSGEYTTELAK--R 575
Query: 1338 NRDWLDSPWDDFF--KKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGR 1165
D W + DP+ T + P G LH + + + R
Sbjct: 576 KPDEFAIDWSKYLVGTAADPV---DTRVKRNELDRLAKLITTIPAGVELHARVAKIYEDR 632
Query: 1164 QQMLKDNSL-DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYN 988
+M N DW E LA+ +LL EG +RL GQD RGTF HRH +LHDQK D Y
Sbjct: 633 VKMAAGNQDGDWGFAENLAYATLLAEGHKLRLVGQDAGRGTFFHRHAILHDQKTDS-YYL 691
Query: 987 PLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQF 808
PL L E + T+ +S LSE AV+GFE GYS DPN+L +WEAQFGDF+N AQ +IDQF
Sbjct: 692 PLRQLVENPEDATIIDSLLSEEAVMGFEYGYSTTDPNALCVWEAQFGDFANGAQVVIDQF 751
Query: 807 ISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEA 628
I++G++KW R +GL + LPHGYEG GPEHSSAR ERFLQ+C A E
Sbjct: 752 IAAGEAKWGRIAGLSLFLPHGYEGQGPEHSSARLERFLQLC-----------ALE----- 795
Query: 627 QQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGS 448
N +V TTPA +H++RRQ+ M RKP VV +PKSLLRH +A S +E+ G
Sbjct: 796 ------NMLVCVPTTPAQCFHMIRRQMRMTTRKPLVVMTPKSLLRHKLAVSTLEELADG- 848
Query: 447 NFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYD 268
FQ +IP+ A + VKRVV C+GKVYYD++ + G ++DVA++RVEQL PFP
Sbjct: 849 QFQHLIPDAKADASK---VKRVVLCSGKVYYDLLEDQTKRG-QDDVAILRVEQLYPFPRA 904
Query: 267 LVQQECRKY-QGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATG 91
+ E +++ A+++W QEE +N GAW ++ +N L+ G++ YAGR S SPA G
Sbjct: 905 QLAAELKRFGNAADVVWCQEEPQNQGAWYQIRHHLNFCLA-SGQSLHYAGRARSPSPAAG 963
Query: 90 NKFTHMQEQKEMMS 49
+ H+ EQ+++++
Sbjct: 964 HMADHIAEQQKLVA 977
>gi|29418063|gb|AAO39689.1| 2-oxoglutarate dehydrogenase E1 component;
SucA [Enterobacter cloacae]
Length = 927
Score = 673 bits (1736), Expect = 0.0
Identities = 390/972 (40%), Positives = 541/972 (55%), Gaps = 11/972 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
FL+G++ +IEQ+YE +L DP SV +W + F+ + +
Sbjct: 14 FLSGANQSWIEQLYEDFLTDPDSVDANWRSMFQQLPGTGVKPDQFHSKTRDYFRRL---- 69
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDD 2581
A + S+ + DTNA +K+ LI +Y+ RGH A+LDPLG+ D
Sbjct: 70 --AKDASRYSSAISDPDTNAK------QVKVLQLINAYRFRGHQHANLDPLGLWQQDRVA 121
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
+ P +++ L E D F + +F K ++ L +++ LK YC S G EYMH+
Sbjct: 122 DLDP----AYHDLTEADFQESFNVG--SFAIGKDTMKLGDLIDALKQTYCGSIGAEYMHI 175
Query: 2400 NNLEQQDWIRRRFEAPRV-TELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCE 2224
+ E++ WI++R E+ S D+KK L + E +L K+P KRF LEG +
Sbjct: 176 TSTEEKRWIQQRIESVAGHATFSADEKKRFLNELTAAEGLERYLGAKFPGAKRFSLEGGD 235
Query: 2223 VLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSG 2044
L+P +K++I + G V+GM HRGRLNVL NV + + +F+ G+G
Sbjct: 236 ALVPMLKELIRHAGKSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTG 295
Query: 2043 DVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMA 1864
DVKYH+G + V +A+ NPSHLE V PVV+G VRA + ++ +
Sbjct: 296 DVKYHMGFSSDIETEGGL--VHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLP 353
Query: 1863 ILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDV 1687
I +HGDAA GQGVV ET N+ Y G + IV+NNQ+GFTT +P +RS+PYCTD+
Sbjct: 354 ITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDI 413
Query: 1686 GRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQP 1507
G++V PIFHVN DDPEAV V +A D+R TFK+DV +DL CYRRHGHNE DEP TQP
Sbjct: 414 GKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLFCYRRHGHNEADEPSATQP 473
Query: 1506 LMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRD- 1330
LMYQ+IK+ T + Y +K+ ++ V + E + Y L DA E K N
Sbjct: 474 LMYQKIKKHPTPRKIYADKLESDKVTTLEDATEMVNLYRDAL-DAGECVVKELRPMNMHS 532
Query: 1329 -----WLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGR 1165
+L+ WD+ + + +K + S P+ + + + R
Sbjct: 533 FTWSPYLNHEWDESYPNKVEMK---------RLQELAKRISTVPDAIEMQSRVAKIYADR 583
Query: 1164 QQMLKDNSL-DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYN 988
Q M L DW E LA+ +L+ EGI VRLSG+D RGTF HRH V+H+Q + Y
Sbjct: 584 QSMAAGEKLFDWGGAETLAYATLVDEGIPVRLSGEDAGRGTFFHRHAVVHNQS-NGSTYT 642
Query: 987 PLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQF 808
PL + GQG++ V +S LSE AVL FE GY+ +P +L IWEAQFGDF+N AQ +IDQF
Sbjct: 643 PLQHVHNGQGQFKVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQF 702
Query: 807 ISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEA 628
ISSG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 703 ISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQ---------------- 746
Query: 627 QQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGS 448
N V +TPA +YH+LRRQ R+P VV SPKSLLRHP+A S +E+ +G+
Sbjct: 747 ------NMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGT 800
Query: 447 NFQRVIPETGAPSQ-NPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPY 271
+P G + +P VKRVV C+GKVYYD++ R+ + DVA+VR+EQL PFP+
Sbjct: 801 ----FLPAIGEIDELDPQGVKRVVMCSGKVYYDLLEQRRK-NDQKDVAIVRIEQLYPFPH 855
Query: 270 DLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPAT 94
+Q+ ++Y + +W QEE N GAW Q ++ G A +YAGR S+SPA
Sbjct: 856 QAMQEVLKQYAHVHDFVWCQEEPLNQGAWYCSQHHFREVIPF-GSALRYAGRPASASPAV 914
Query: 93 GNKFTHMQEQKE 58
G H ++Q++
Sbjct: 915 GYMSVHQKQQQD 926
>gi|32475700|ref|NP_868694.1| alpha-ketoglutarate dehydrogenase E1
[Pirellula sp. 1]
gi|32446242|emb|CAD76071.1| alpha-ketoglutarate dehydrogenase E1
[Pirellula sp.]
Length = 969
Score = 667 bits (1722), Expect = 0.0
Identities = 393/990 (39%), Positives = 544/990 (54%), Gaps = 24/990 (2%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRN--------VEXXXXXXXXXXXXXXXAY 2782
+N S YI+ +Y +++DPSSV +W YF A
Sbjct: 14 MNSYSLDYIDDLYVQYVRDPSSVSETWRQYFEQFLVGAGARTNAAPAASQTASQGDASAN 73
Query: 2781 AGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHL------------KIQLLIRSYQTR 2638
G A S P + DT+ S D ++ L+R Y+ R
Sbjct: 74 GKTSGARSVVAPAFASGQPGSAEDTSERPGSTGDQNVDQALWLARIQDRVDQLVREYRVR 133
Query: 2637 GHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREI 2458
GH +A LDPLG L + PEL +GL ++DL R F ++ + TL I
Sbjct: 134 GHLVATLDPLG-----LFEHTCPELSPRSHGLSKQDLARPF---DSSILENVSGSTLDVI 185
Query: 2457 LQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVT-ELSHDQKKVLFKRLIRSTKFE 2281
L +L+ YC S G ++MH++N +DW++RR E +LSH+ ++ ++ RL +T FE
Sbjct: 186 LNKLQSTYCRSIGAQFMHIDNRNIRDWLQRRMETTENRLDLSHEVQRRIYTRLADATIFE 245
Query: 2280 EFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQP 2101
EF+ +K+ K F LEG E LIP + ++ + V V+ M HRGRLNV+AN+ ++
Sbjct: 246 EFVRRKFVGAKTFSLEGAESLIPLIDLALEKAGQHQVKEVVMAMAHRGRLNVMANILKKR 305
Query: 2100 LATILSQFSTLEPA-DEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVM 1924
I F P G GDV+YHLG + S + I++ NPSHLE V+ V +
Sbjct: 306 AMNIFWSFDDPTPELSRGGGDVRYHLGYSSD-WKTASGDRLHISLCFNPSHLEYVNTVAL 364
Query: 1923 GKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQ 1744
G+ R + GD M IL+HGDAAFAG+GVV ET NL +L Y T G +H+V+NNQ
Sbjct: 365 GRTRCKQDNRGDVDRQDVMTILIHGDAAFAGEGVVQETLNLSELKGYRTGGTLHVVINNQ 424
Query: 1743 IGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDL 1564
+GFTT+P RS+ Y TD+ +++ PIFHVN +DPEAV V ++A D+RK F +DV++DL
Sbjct: 425 VGFTTEPDEGRSTTYATDIAKMLQIPIFHVNGEDPEAVAQVVSLAMDFRKEFHRDVVIDL 484
Query: 1563 VCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSI 1384
YRR GHNE DEP FTQP MY I + ++Y ++L G E E
Sbjct: 485 YAYRRWGHNEGDEPRFTQPQMYAEIDRRPGVRQQYLNRLLKLGKITEAEADEISRDRTEK 544
Query: 1383 LEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGF 1204
LE +E ++ ++V + L + W ++F +P T I ++ PEGF
Sbjct: 545 LESEFEASKHESFVPDTQTLAANWMEYFGGPEPADEVDTTIPATRLSELIDSLTRLPEGF 604
Query: 1203 NLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHH 1027
+ H+ L+R ++ R++M + LDWA EA AF SLL G +RL+GQD +RGTFSHRH
Sbjct: 605 SPHKKLKRPMQQRREMASGERPLDWATAEAAAFASLLDAGHPIRLTGQDCERGTFSHRHA 664
Query: 1026 VLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFG 847
VLHD + D Y PL +L E Q + NS LSE VLGFE GYS+ P+ L +WEAQFG
Sbjct: 665 VLHDMR-DGNEYCPLKNLHENQARLELYNSPLSEAGVLGFEYGYSLDCPSGLCMWEAQFG 723
Query: 846 DFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEI 667
DF N AQ I+DQFI+S + KW R SGLVMLLPHG+EG GPEH SAR ERFL M ED
Sbjct: 724 DFWNAAQVIVDQFIASAEDKWNRLSGLVMLLPHGFEGQGPEHCSARVERFLAMAAED--- 780
Query: 666 DLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHP 487
N + TTPA +HLLRRQV +RKP +V +PKSLLRH
Sbjct: 781 -------------------NIQICQPTTPAQYFHLLRRQVIRKWRKPLIVLTPKSLLRHA 821
Query: 486 MARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVA 307
SP++ GS F++++P+ P + KR+V CTGKVYYD++ R E DV
Sbjct: 822 EVTSPLDVVAEGS-FRKILPDRKVPLEG---AKRLVLCTGKVYYDLLQERTDRNIE-DVP 876
Query: 306 LVRVEQLSPF-PYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATK 130
++R+EQL P P ++ +G+EI W QEE +NMGAW +++ +I L+ R TK
Sbjct: 877 IMRLEQLYPLSPDEIFAAFEGLAEGSEIRWVQEEPENMGAWPYLKLKIGDELNKRFRFTK 936
Query: 129 YAGRLPSSSPATGNKFTHMQEQKEMMSKVF 40
A R S+SP+TG+ H EQ +++ F
Sbjct: 937 -ATRAESASPSTGSMAAHKLEQIDLLKAAF 965
>gi|47575379|ref|ZP_00245414.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Rubrivivax gelatinosus PM1]
Length = 952
Score = 667 bits (1722), Expect = 0.0
Identities = 400/991 (40%), Positives = 558/991 (55%), Gaps = 14/991 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L G ++ Y+E++YE++L +P SV W AYF ++ A V
Sbjct: 10 YLFGGNAPYVEELYESYLDNPGSVPEKWRAYFDALQHVPATDGSESRDVAHA-----PVV 64
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDD 2581
+ AQ ++A A + A + + +Q LI +Y+T G ADLDPL +
Sbjct: 65 ESFAQRAKANAFAVKASA-AELAVARKQVHVQSLIAAYRTLGARWADLDPL----KRTER 119
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
PELE +FY L E D+D F T F + ++ TLREILQ L++ YC S G E+MH+
Sbjct: 120 PKIPELEPAFYDLSESDMDITFSATNTYFTTAEQQ-TLREILQALRETYCGSIGAEFMHI 178
Query: 2400 NNLEQQDWIRRRFEAPRVT-ELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCE 2224
++ W ++R E+ R S QK + RL S E +L K+ +KRF LEG E
Sbjct: 179 TEPVEKRWWQQRLESVRAKPSFSAAQKTHILDRLTASEGLERYLHTKYVGQKRFSLEGGE 238
Query: 2223 VLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSG 2044
I +M +V+ GV VIGM HRGRLNVL N + + ++F + +G
Sbjct: 239 SFIASMDEVVQRGGERGVQEIVIGMAHRGRLNVLVNTLGKMPKDLFAEFDHTAKEELPAG 298
Query: 2043 DVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMA 1864
DVKYH G + V +++ NPSHLE V+PVV G V+A GD++ D +
Sbjct: 299 DVKYHQGFSSDVTTPGGP--VHLSLSFNPSHLEIVNPVVEGSVKARLDRRGDKEGDTVLP 356
Query: 1863 ILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDV 1687
+L+HGDAAFAGQGVV+ET L Y T G +H+V+NNQIGFTT DPR SRS+ YCTDV
Sbjct: 357 VLVHGDAAFAGQGVVMETLALAQTRGYYTGGTVHLVINNQIGFTTSDPRDSRSTLYCTDV 416
Query: 1686 GRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQP 1507
+++ P+ HVN DDPEAV+ +A D+R+ F KDV+VD++C+R+ GHNE D P TQP
Sbjct: 417 VKMIEAPVLHVNGDDPEAVVLCTQLALDYRQEFNKDVVVDIICFRKLGHNEQDTPSLTQP 476
Query: 1506 LMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKV-TYVRNR- 1333
LMY++I + Y +K++ +G + + + ++ V T +++
Sbjct: 477 LMYKKIAAHPGTRKLYADKLVAQGTLKPDEPDAMVKAFRAAMDAGKHTVDPVLTNYKSKY 536
Query: 1332 --DW---LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKG 1168
DW L+ W D PL + + P+GF +H +E+ L
Sbjct: 537 AVDWTPYLNRKWTDAADTALPL---------AEIKRLAERITTIPKGFKVHPLVEKVLAD 587
Query: 1167 RQQMLKDN-SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQ---KVDQ 1000
R M + ++DW GE LA+ SL+ G VRLSG+D RGTF+HRH VLHDQ K D+
Sbjct: 588 RAAMGRGEINVDWGMGEHLAYASLVASGYPVRLSGEDCGRGTFTHRHAVLHDQNREKWDE 647
Query: 999 KIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCI 820
+ PL +++GQ + V +S LSE AVLGFE GY+ DP +L IWEAQFGDF N AQ +
Sbjct: 648 GTWTPLQHVADGQAPFVVIDSILSEEAVLGFEYGYASADPTTLTIWEAQFGDFVNGAQVV 707
Query: 819 IDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEG 640
IDQFI+SG+ KW R +GL +LLPHGYEG GPEHSSAR ERF+Q+
Sbjct: 708 IDQFIASGEVKWGRANGLTLLLPHGYEGQGPEHSSARLERFMQLA--------------- 752
Query: 639 TFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDF 460
D N V T+ + I+HLLRRQ FRKP VV +PKSLLR+ A SP+ +F
Sbjct: 753 -------ADNNMQVCQPTSASQIFHLLRRQQVRMFRKPLVVMTPKSLLRNKDAASPLSEF 805
Query: 459 QSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSP 280
G F+ VIPE A + VKRV+ C+GKVYYD+V R+ K DV ++RVEQL P
Sbjct: 806 TRG-EFRTVIPEQNA-DIDAAKVKRVIACSGKVYYDLV-KRRDEKKSTDVVILRVEQLYP 862
Query: 279 FPYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSS 103
FP+ E +KY A +++W Q+E +N GAW FVQ ++ + ++G+ YAGR S+S
Sbjct: 863 FPHKAFATELKKYPNATDVVWCQDEPQNQGAWFFVQHYVHENM-LEGQKLGYAGRPASAS 921
Query: 102 PATGNKFTHMQEQKEMMSKVFGVPKSKLEGF 10
PA G H ++ K ++ + +G KL+GF
Sbjct: 922 PAVGYAHLHQEQLKALLDQAYG----KLKGF 948
>gi|16121413|ref|NP_404726.1| 2-oxoglutarate dehydrogenase E1
component [Yersinia pestis]
gi|22126943|ref|NP_670366.1| 2-oxoglutarate dehydrogenase
(decarboxylase component) [Yersinia pestis KIM]
gi|45440877|ref|NP_992416.1| 2-oxoglutarate dehydrogenase E1
component [Yersinia pestis biovar Medievalis str. 91001]
gi|25284474|pir||AI0136 oxoglutarate dehydrogenase (lipoamide) (EC
1.2.4.2) E1 component [imported] - Yersinia pestis
(strain CO92)
gi|15979180|emb|CAC89956.1| 2-oxoglutarate dehydrogenase E1 component
[Yersinia pestis CO92]
gi|21959983|gb|AAM86617.1| 2-oxoglutarate dehydrogenase
(decarboxylase component) [Yersinia pestis KIM]
gi|45435735|gb|AAS61293.1| 2-oxoglutarate dehydrogenase E1 component
[Yersinia pestis biovar Medievalis str. 91001]
Length = 935
Score = 667 bits (1721), Expect = 0.0
Identities = 384/986 (38%), Positives = 551/986 (54%), Gaps = 17/986 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L G++ YIEQ+YE +L DP SV SW + F+ + GV
Sbjct: 14 YLAGANQSYIEQLYEDFLTDPGSVDDSWRSIFQQLPTT-------------------GVK 54
Query: 2760 PAAAQVTTS------SAPATRLDTNASVQSI-SDHLKIQLLIRSYQTRGHNIADLDPLGI 2602
P T + +TR +++ + I + +K+ LI +++ RGH A+LDPLG+
Sbjct: 55 PDQLHSQTREYFRRLAKDSTRYNSSINDPDIDAKQVKVLQLINAFRFRGHQHANLDPLGL 114
Query: 2601 NSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTST 2422
+ P+L+ S++ L E D F + +F K+++ L ++ LK YC S
Sbjct: 115 WKQES----VPDLDPSYHNLTEADFQNTFNVG--SFAIGKETMKLADLYAALKQTYCGSV 168
Query: 2421 GVEYMHLNNLEQQDWIRRRFEAP-RVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKR 2245
G EYMH+ N E++ WI++R E+ S +K+ L + E +L K+P KR
Sbjct: 169 GAEYMHITNTEEKRWIQQRIESVVGKPTFSDAEKRRFLSELTAAEGLERYLGAKFPGAKR 228
Query: 2244 FGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLE 2065
F LEG + L+ +K++I + G V+GM HRGRLNVL NV + + +F+
Sbjct: 229 FSLEGGDSLVTMLKEMIRHAGKNGTREVVLGMAHRGRLNVLINVLGKKPEDLFDEFAGKH 288
Query: 2064 PADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDE 1885
G+GDVKYH G + V +A+ NPSHLE V PVV+G VRA +
Sbjct: 289 KEHLGTGDVKYHQGFSSDVETEGGL--VHLALAFNPSHLEIVSPVVIGSVRARRDRLDEA 346
Query: 1884 KCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRS 1708
+ + + I +HGDAA GQGVV ET N+ Y G + IV+NNQIGFTT +P +RS
Sbjct: 347 RSNMVLPITIHGDAAITGQGVVQETLNMSQARGYEVGGTVRIVINNQIGFTTSNPLDARS 406
Query: 1707 SPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELD 1528
+ YCTD+ ++V PIFHVN DDPEAV V +A D+R TFK+DV++DLVCYRRHGHNE D
Sbjct: 407 TQYCTDIAKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVMIDLVCYRRHGHNEAD 466
Query: 1527 EPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILE--DAYENAQK 1354
EP TQP+MYQ+IK+ T + Y +K++ + +A+ + E + Y L+ D +
Sbjct: 467 EPSATQPVMYQKIKKHPTPRKIYADKLIEQNIASLEDATEMVNLYRDALDHGDCVVEEWR 526
Query: 1353 VTYVRNRDW---LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLE 1183
+++ W L+ WD+ + + +K + S PE + +
Sbjct: 527 PMNLQSFTWSPYLNHEWDEAYPSKVEMK---------RLQELARRISSAPEAIEMQSRVA 577
Query: 1182 RTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKV 1006
+ R M + DW E LA+ +L+ EGI +RLSG+D RGTF HRH V+H+QK
Sbjct: 578 KIYSDRALMASGEKPFDWGGAETLAYATLVDEGIPIRLSGEDAGRGTFFHRHAVIHNQK- 636
Query: 1005 DQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQ 826
+ +Y PL+++ GQG++ V +S LSE AVL FE GY+ +P +L IWEAQFGDF+N AQ
Sbjct: 637 NGSVYVPLSNIHSGQGDFQVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQ 696
Query: 825 CIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAF 646
+IDQFISSG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 697 VVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQ---------- 746
Query: 645 EGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVE 466
N V +TPA +YH++RRQ R+P +V SPKSLLRHP+A S ++
Sbjct: 747 ------------NMQVCIPSTPAQVYHMIRRQALRGMRRPLIVMSPKSLLRHPLATSSLD 794
Query: 465 DFQSGSNFQRVIPETGAPSQ-NPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQ 289
+ +GS +P G + +P +KRVV C+GKVYYD++ R+ G + DVA+VR+EQ
Sbjct: 795 ELANGS----FLPAIGEIDELDPKGIKRVVMCSGKVYYDLLEQRRKNG-QTDVAIVRIEQ 849
Query: 288 LSPFPYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLP 112
L PFP+ VQ +Y + +W QEE N GAW Q ++ G + +YAGR
Sbjct: 850 LYPFPHQAVQSVLEQYAHVHDFVWCQEEPLNQGAWYCSQHNFREVIPF-GASLRYAGRPA 908
Query: 111 SSSPATGNKFTHMQEQKEMMSKVFGV 34
S+SPA G H ++Q+ +++ V
Sbjct: 909 SASPAVGYLSVHQKQQQALVNDALNV 934
>gi|50120300|ref|YP_049467.1| 2-oxoglutarate dehydrogenase E1
component [Erwinia carotovora subsp. atroseptica
SCRI1043]
gi|49610826|emb|CAG74271.1| 2-oxoglutarate dehydrogenase E1 component
[Erwinia carotovora subsp. atroseptica SCRI1043]
Length = 935
Score = 667 bits (1721), Expect = 0.0
Identities = 390/982 (39%), Positives = 544/982 (54%), Gaps = 13/982 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L G++ YIEQ+YE +L DP S+ SW + F+ + GV
Sbjct: 14 YLAGANQSYIEQLYEDFLTDPDSIEHSWRSIFQQLPTS-------------------GVK 54
Query: 2760 PAAAQVTTSSAPATRL--DTNASVQSISD------HLKIQLLIRSYQTRGHNIADLDPLG 2605
P T RL D++ S++D +K+ LI +++ RGH A+LDP+
Sbjct: 55 PDQLHSKTRDY-FRRLAKDSSRFTSSVTDPDIDVKQVKVLQLINAFRFRGHQQANLDPIF 113
Query: 2604 INSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTS 2425
+ + EL+L ++ L + DL F + +F K ++ L ++ LK YC S
Sbjct: 114 LRPQEP----VAELDLDYHNLTQDDLQESFNVG--SFAIGKDTMKLEDLYDALKRTYCGS 167
Query: 2424 TGVEYMHLNNLEQQDWIRRRFEAPR-VTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEK 2248
G EYMH+ + E++ WI++R E+ + ++K+ K L + E +L K+P K
Sbjct: 168 IGAEYMHMTSTEEKRWIQQRIESVTGQPSFTVEEKRRFLKELTAAEGLERYLGAKYPGAK 227
Query: 2247 RFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTL 2068
RF LEG + L+P +K++I + V+GM HRGRLNVL NV + + +F+
Sbjct: 228 RFSLEGADALVPMLKELIRHAGANDTREVVLGMAHRGRLNVLINVLGKKSQDLFDEFAGK 287
Query: 2067 EPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGD 1888
G+GDVKYH G E V +A+ NPSHLE V PVV G VRA
Sbjct: 288 HKEHLGTGDVKYHQGFSSEFDTAGGL--VHLALAFNPSHLEIVSPVVTGSVRARLDRLNS 345
Query: 1887 EKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSR 1711
+ R + I +HGDAA +GQGVV E N+ + Y G + IV+NN+IGFTT +P R
Sbjct: 346 QSGPRVLPITIHGDAAISGQGVVQELLNMSTVRGYEVGGTLRIVINNRIGFTTSNPLDIR 405
Query: 1710 SSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNEL 1531
S+ YCTDVG++V PIFHVN DDPEAV V +A D+R FK+DV +DL+CYRRHGHNE
Sbjct: 406 STEYCTDVGKMVQAPIFHVNADDPEAVAFVTRLALDFRNAFKRDVFIDLICYRRHGHNEA 465
Query: 1530 DEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKV 1351
DEP TQP+MYQ+IK+ T + Y +++ E + +E+ T+ ++ DA + + V
Sbjct: 466 DEPSATQPMMYQKIKKHPTPRKVYADRLEQE----KTITQEDATEMVNLFRDALDAGECV 521
Query: 1350 TYV-RNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTL 1174
R D W + P + + S+ PEG +H + +
Sbjct: 522 VDEWREMDMQSFTWTPYLNHEWDEPYPHS-TEMKRLQELAKRISEVPEGIEIHPRVAKVY 580
Query: 1173 KGRQQMLKDNS-LDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQK 997
R +M N DW E LA+ +L+ EGI +RLSG+D RGTF HRH V+H+QK +
Sbjct: 581 SDRAEMAAGNKPFDWGGAETLAYATLVDEGIPIRLSGEDSGRGTFFHRHAVVHNQK-NGS 639
Query: 996 IYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCII 817
Y PLN + GQGE+ V +S LSE A+L FE GY+ +P +L IWEAQFGDF+N AQ +I
Sbjct: 640 SYTPLNHVHNGQGEFNVWDSVLSEEAILAFEYGYATAEPRTLTIWEAQFGDFANGAQVVI 699
Query: 816 DQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGT 637
DQFISSG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 700 DQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQ------------- 746
Query: 636 FEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQ 457
N V +TPA +YH+LRRQ R+P VV SPKSLLRHP+A S +++
Sbjct: 747 ---------NMQVCIPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAISSLDELA 797
Query: 456 SGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPF 277
+GS FQ I E +P VKRVV C+GKVYYD++ R+ ++ DVA+VR+EQL PF
Sbjct: 798 NGS-FQPAIGE--VEELDPAAVKRVVLCSGKVYYDLLEQRRK-NEQKDVAIVRIEQLYPF 853
Query: 276 PYDLVQQECRKY-QGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSP 100
P+ VQ + Q + +W QEE N GAW Q + ++ G + +YAGR S+SP
Sbjct: 854 PHQAVQAALEPFSQVHDFVWCQEEPLNQGAWYCSQHHLREVIPF-GSSLRYAGRPASASP 912
Query: 99 ATGNKFTHMQEQKEMMSKVFGV 34
A G H ++QK+++ V
Sbjct: 913 AVGYMSVHQKQQKDLVDDALNV 934
>gi|30995467|ref|NP_439804.2| unknown protein [Haemophilus influenzae
Rd KW20]
gi|1171886|sp|P45303|ODO1_HAEIN 2-oxoglutarate dehydrogenase E1
component (Alpha-ketoglutarate dehydrogenase)
Length = 935
Score = 667 bits (1720), Expect = 0.0
Identities = 389/979 (39%), Positives = 550/979 (55%), Gaps = 17/979 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G++ YIE++YE++L DP SV SW F ++ A
Sbjct: 16 LGGANQSYIEELYESYLSDPQSVEESWRKTFDSLPKTTALEQPHTPVRDYFRRLARENHN 75
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 2578
A V +A A + K+ I +Y+ RGH A+LDPL N +
Sbjct: 76 EAVTVIDPAAGAKLV-------------KVLQFINAYRFRGHLEANLDPL--NYYRWKVS 120
Query: 2577 IPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLN 2398
PEL+ +G E+DL+ F + ++ ++ ++ L E+ Q LK+ YC S G+E+MH+
Sbjct: 121 FVPELDYRHHGFTEQDLNETFNI--NHYVYKRDTIKLGELAQMLKETYCGSIGLEFMHVQ 178
Query: 2397 NLEQQDWIRRRFEAPRVTELSHDQKKVLFKR-LIRSTKFEEFLAKKWPSEKRFGLEGCEV 2221
++EQ+ W++ + E+ L +++V F R L + E +L K+P KRF LEG +
Sbjct: 179 DMEQKMWLQSKMESLLDKPLFTSEERVNFLRELTAADGLERYLGAKFPGAKRFSLEGSDA 238
Query: 2220 LIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGD 2041
IP MK++I SS GV+ V+GM HRGRLN+L NV + + +F+ + + E +GD
Sbjct: 239 FIPLMKEIIRHSSRQGVNDVVMGMAHRGRLNMLVNVLGKKPENLFDEFAG-KHSSERTGD 297
Query: 2040 VKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAI 1861
VKYH G + K V + + NPSHLE V PVV+G VR+ D + + +AI
Sbjct: 298 VKYHQGFSSDFA--VDDKRVHLTLAFNPSHLEIVSPVVIGSVRSRQTRMNDTEHSKVLAI 355
Query: 1860 LLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDVG 1684
+HGD+A AGQGVV ET N+ + Y+ G I IV+NNQIGFTT +P +RS+ YCTD+
Sbjct: 356 TVHGDSAVAGQGVVQETLNMSNTRGYSVGGTIRIVINNQIGFTTSNPNDTRSTEYCTDIA 415
Query: 1683 RVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPL 1504
+++ PI HVN DDPEAV +A ++R FK+D+ +DL+ YRRHGHNE DEP+ TQP+
Sbjct: 416 KMIQAPIIHVNGDDPEAVAFAARMAVEYRNLFKRDIFIDLISYRRHGHNEADEPLATQPM 475
Query: 1503 MYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTY------V 1342
MY IK+ T + Y +++++EGV E+ V E Y DA +N +V
Sbjct: 476 MYSIIKKHPTPRKVYADRLVSEGVMTEEQVTEMANDY----RDALDNGDRVVSEWREMDT 531
Query: 1341 RNRDWLD-------SPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLE 1183
DWL +P++ F + L L + +YPE H +E
Sbjct: 532 AKMDWLQYLNYDWTAPYESKFSQERFLTLAK-------------RVCEYPESLRAHPRVE 578
Query: 1182 RTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKV 1006
+ R+ M + + LDW E +A+ +LL EG++VRLSG+D RGTF HRH V+H+Q
Sbjct: 579 KIYNDRKAMYQGEKLLDWGMAETMAYATLLDEGVNVRLSGEDAGRGTFFHRHAVVHNQN- 637
Query: 1005 DQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQ 826
D Y PL L QG + V +S LSE +VL FE GY+ DP +L IWEAQFGDF+N AQ
Sbjct: 638 DGTGYVPLTHLHANQGRFEVWDSVLSEESVLAFEYGYATTDPKTLTIWEAQFGDFANGAQ 697
Query: 825 CIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAF 646
+IDQFISSG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 698 IVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQ---------- 747
Query: 645 EGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVE 466
N V +TPA +YH+LRRQ R+P + SPKSLLRHP+A S ++
Sbjct: 748 ------------NMQVCVPSTPAQVYHMLRRQSLRKMRRPLIAISPKSLLRHPLAVSSLD 795
Query: 465 DFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQL 286
+ +G+ FQ VI E +P DVKRVV C+GKVYYD++ R+ + DVA++R+EQL
Sbjct: 796 ELINGT-FQTVIGE--IDELDPKDVKRVVMCSGKVYYDLLEQRR-ANNQKDVAIIRIEQL 851
Query: 285 SPFPYDLVQQECRKY-QGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPS 109
PFP++ V++ Y + +W QEE N GAW + S + + KYAGR S
Sbjct: 852 YPFPHEDVKKALEPYAHVTDYVWCQEEPLNQGAWYCSKHNFESAIP-ESVKLKYAGRPAS 910
Query: 108 SSPATGNKFTHMQEQKEMM 52
+SPA G H ++QK+++
Sbjct: 911 ASPAVGYMSLHTKQQKQLV 929
>gi|15838151|ref|NP_298839.1| oxoglutarate dehydrogenase [Xylella
fastidiosa 9a5c]
gi|11252268|pir||F82668 oxoglutarate dehydrogenase XF1550 [imported]
- Xylella fastidiosa (strain 9a5c)
gi|9106591|gb|AAF84359.1| oxoglutarate dehydrogenase [Xylella
fastidiosa 9a5c]
Length = 967
Score = 667 bits (1720), Expect = 0.0
Identities = 399/980 (40%), Positives = 552/980 (55%), Gaps = 17/980 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G ++ YIE +YE +L P+SV W AYF + AG + S
Sbjct: 39 LAGGNAAYIEDLYEQYLVSPNSVDPKWKAYFDGFKGRD--------------AGDIPHSA 84
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLK--IQLLIRSYQTRGHNIADLDPLGINSADLD 2584
A +T ++ + + + Q SD + I LI +Y++RGH A +DPLG+
Sbjct: 85 VIAHITDTAKQSVKAKSR---QDASDERERNIGRLITAYRSRGHLSARIDPLGLTPP--- 138
Query: 2583 DTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMH 2404
+ PP+L+L F+ L + DLD EF T I + + LR +L LK Y + G E+MH
Sbjct: 139 -SNPPDLDLPFHHLSQADLDNEF---STGGIGGQPRMKLRNLLAHLKATYTDTIGTEFMH 194
Query: 2403 LNNLEQQDWIRRRFE--APRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEG 2230
++ EQ+ WI RR E ++ + ++K++L +RL + E +L K+ +KRF LEG
Sbjct: 195 ISEFEQRQWIYRRLENVGGKIASNATNRKRIL-ERLTAAEGLERYLHTKYVGQKRFSLEG 253
Query: 2229 CEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEPADE 2053
+ LIP M ++ + V V+GM HRGRLNVL N + + +F E A
Sbjct: 254 SDTLIPLMDTLVRQAGNNDVKDIVVGMAHRGRLNVLVNTLGKNPRKLFDEFEGKFEHAHH 313
Query: 2052 G---SGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEK 1882
+GDVKYH+G + + K V +A+ NPSHLE VDPVV G VR+ GD +
Sbjct: 314 DRAHTGDVKYHMGFSAD-IAVGDGKQVHLALAFNPSHLEIVDPVVAGSVRSRQERFGDTE 372
Query: 1881 CDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRS-SRSS 1705
+ IL+HGDAAFAGQGVV+E + + G +H+++NNQIGFTT R +RS+
Sbjct: 373 RKTVLPILIHGDAAFAGQGVVMELLQMSQARGFAVGGTLHVIINNQIGFTTSARDDARST 432
Query: 1704 PYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDE 1525
PYCTDV +++G P+FHVN DDP+AV+ V +A ++R+ FKKDV++DLVCYRR GHNE DE
Sbjct: 433 PYCTDVAKMIGAPVFHVNGDDPDAVVFVAQLAYEFRQQFKKDVVIDLVCYRRWGHNEADE 492
Query: 1524 PMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAY---ENAQK 1354
P TQP+MYQ I++ KT E Y K+ EGV K + Y + L+ E A K
Sbjct: 493 PAATQPVMYQTIRKHKTTRELYATKLEAEGVIAAGEAKAMVDDYRAKLDSGKFTTELASK 552
Query: 1353 VTYVRNRDW---LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLE 1183
T DW L DD K T + P LH +
Sbjct: 553 HTDEFVIDWSKYLSGKLDDTVK---------TSVKRQTLNKLAALINTIPATVELHPRVA 603
Query: 1182 RTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKV 1006
+ + R +M + DW E LA+ +LL EG +RL GQD RGTF HRH +LHDQK
Sbjct: 604 KIYEDRIKMAAGEQPGDWGFAENLAYATLLAEGHKLRLVGQDAGRGTFFHRHAILHDQKT 663
Query: 1005 DQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQ 826
D Y PL L + TV +S LSE AV+GFE GYS DPN+L IWEAQFGDF+N AQ
Sbjct: 664 DS-YYLPLRQLVSNPDDATVIDSLLSEEAVMGFEYGYSTTDPNTLCIWEAQFGDFANGAQ 722
Query: 825 CIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAF 646
+IDQFI++G+ KW R SGL + LPHGYEG GPEHSSAR ERFLQ+C A
Sbjct: 723 VVIDQFIAAGEVKWGRISGLSLFLPHGYEGQGPEHSSARLERFLQLC-----------AL 771
Query: 645 EGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVE 466
E N +V TTPA +H++RRQ+ M RKP VV +PKSLLRH +A S ++
Sbjct: 772 E-----------NMLVCVPTTPAQAFHMIRRQMRMSTRKPLVVMTPKSLLRHKLAVSTLD 820
Query: 465 DFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQL 286
+ +G FQ +IP+ A +P VKR+V C GKVYYD + + +ND+A++R+EQL
Sbjct: 821 ELANG-KFQHIIPDDAA---DPKHVKRIVMCAGKVYYD-ILENQQKRSQNDLAIIRIEQL 875
Query: 285 SPFPYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPS 109
PFP L+ E +++ A +++W QEE +N GAW ++ + ++L+ + YAGR S
Sbjct: 876 YPFPRALLASELKRFNKATDVVWCQEEPQNQGAWYQIKHHLQAVLA-HAQRLHYAGRSSS 934
Query: 108 SSPATGNKFTHMQEQKEMMS 49
SPA G+ HM EQ+ +++
Sbjct: 935 PSPAVGHMAEHMAEQESLVA 954
>gi|1073780|pir||E64135 oxoglutarate dehydrogenase (lipoamide) (EC
1.2.4.2) - Haemophilus influenzae (strain Rd KW20)
gi|1574512|gb|AAC23308.1| 2-oxoglutarate dehydrogenase E1 component
(sucA) [Haemophilus influenzae Rd KW20]
Length = 950
Score = 667 bits (1720), Expect = 0.0
Identities = 389/979 (39%), Positives = 550/979 (55%), Gaps = 17/979 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G++ YIE++YE++L DP SV SW F ++ A
Sbjct: 31 LGGANQSYIEELYESYLSDPQSVEESWRKTFDSLPKTTALEQPHTPVRDYFRRLARENHN 90
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 2578
A V +A A + K+ I +Y+ RGH A+LDPL N +
Sbjct: 91 EAVTVIDPAAGAKLV-------------KVLQFINAYRFRGHLEANLDPL--NYYRWKVS 135
Query: 2577 IPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLN 2398
PEL+ +G E+DL+ F + ++ ++ ++ L E+ Q LK+ YC S G+E+MH+
Sbjct: 136 FVPELDYRHHGFTEQDLNETFNI--NHYVYKRDTIKLGELAQMLKETYCGSIGLEFMHVQ 193
Query: 2397 NLEQQDWIRRRFEAPRVTELSHDQKKVLFKR-LIRSTKFEEFLAKKWPSEKRFGLEGCEV 2221
++EQ+ W++ + E+ L +++V F R L + E +L K+P KRF LEG +
Sbjct: 194 DMEQKMWLQSKMESLLDKPLFTSEERVNFLRELTAADGLERYLGAKFPGAKRFSLEGSDA 253
Query: 2220 LIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGD 2041
IP MK++I SS GV+ V+GM HRGRLN+L NV + + +F+ + + E +GD
Sbjct: 254 FIPLMKEIIRHSSRQGVNDVVMGMAHRGRLNMLVNVLGKKPENLFDEFAG-KHSSERTGD 312
Query: 2040 VKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAI 1861
VKYH G + K V + + NPSHLE V PVV+G VR+ D + + +AI
Sbjct: 313 VKYHQGFSSDFA--VDDKRVHLTLAFNPSHLEIVSPVVIGSVRSRQTRMNDTEHSKVLAI 370
Query: 1860 LLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDVG 1684
+HGD+A AGQGVV ET N+ + Y+ G I IV+NNQIGFTT +P +RS+ YCTD+
Sbjct: 371 TVHGDSAVAGQGVVQETLNMSNTRGYSVGGTIRIVINNQIGFTTSNPNDTRSTEYCTDIA 430
Query: 1683 RVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPL 1504
+++ PI HVN DDPEAV +A ++R FK+D+ +DL+ YRRHGHNE DEP+ TQP+
Sbjct: 431 KMIQAPIIHVNGDDPEAVAFAARMAVEYRNLFKRDIFIDLISYRRHGHNEADEPLATQPM 490
Query: 1503 MYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTY------V 1342
MY IK+ T + Y +++++EGV E+ V E Y DA +N +V
Sbjct: 491 MYSIIKKHPTPRKVYADRLVSEGVMTEEQVTEMANDY----RDALDNGDRVVSEWREMDT 546
Query: 1341 RNRDWLD-------SPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLE 1183
DWL +P++ F + L L + +YPE H +E
Sbjct: 547 AKMDWLQYLNYDWTAPYESKFSQERFLTLAK-------------RVCEYPESLRAHPRVE 593
Query: 1182 RTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKV 1006
+ R+ M + + LDW E +A+ +LL EG++VRLSG+D RGTF HRH V+H+Q
Sbjct: 594 KIYNDRKAMYQGEKLLDWGMAETMAYATLLDEGVNVRLSGEDAGRGTFFHRHAVVHNQN- 652
Query: 1005 DQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQ 826
D Y PL L QG + V +S LSE +VL FE GY+ DP +L IWEAQFGDF+N AQ
Sbjct: 653 DGTGYVPLTHLHANQGRFEVWDSVLSEESVLAFEYGYATTDPKTLTIWEAQFGDFANGAQ 712
Query: 825 CIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAF 646
+IDQFISSG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 713 IVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQ---------- 762
Query: 645 EGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVE 466
N V +TPA +YH+LRRQ R+P + SPKSLLRHP+A S ++
Sbjct: 763 ------------NMQVCVPSTPAQVYHMLRRQSLRKMRRPLIAISPKSLLRHPLAVSSLD 810
Query: 465 DFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQL 286
+ +G+ FQ VI E +P DVKRVV C+GKVYYD++ R+ + DVA++R+EQL
Sbjct: 811 ELINGT-FQTVIGE--IDELDPKDVKRVVMCSGKVYYDLLEQRR-ANNQKDVAIIRIEQL 866
Query: 285 SPFPYDLVQQECRKY-QGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPS 109
PFP++ V++ Y + +W QEE N GAW + S + + KYAGR S
Sbjct: 867 YPFPHEDVKKALEPYAHVTDYVWCQEEPLNQGAWYCSKHNFESAIP-ESVKLKYAGRPAS 925
Query: 108 SSPATGNKFTHMQEQKEMM 52
+SPA G H ++QK+++
Sbjct: 926 ASPAVGYMSLHTKQQKQLV 944
>gi|28198666|ref|NP_778980.1| oxoglutarate dehydrogenase [Xylella
fastidiosa Temecula1]
gi|28056757|gb|AAO28629.1| oxoglutarate dehydrogenase [Xylella
fastidiosa Temecula1]
Length = 938
Score = 666 bits (1719), Expect = 0.0
Identities = 394/976 (40%), Positives = 553/976 (56%), Gaps = 13/976 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G ++ YIE +YE +L P+SV W AYF + AG + S
Sbjct: 14 LAGGNAAYIEDLYEQYLVLPNSVDPKWKAYFDGFKGRD--------------AGDIPHSA 59
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLK--IQLLIRSYQTRGHNIADLDPLGINSADLD 2584
A +T ++ + + Q SD + I LI +Y++RGH A +DPLG+
Sbjct: 60 VIAHITDTAKQSVK-------QGPSDERERNIGRLITAYRSRGHLGARIDPLGLTPP--- 109
Query: 2583 DTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMH 2404
+ PP+L+L F+ L + DLD EF T I + + LR +L LK Y + G E+MH
Sbjct: 110 -SNPPDLDLPFHNLSQADLDNEF---STGGIGGQPRMKLRNLLAHLKATYTDTIGTEFMH 165
Query: 2403 LNNLEQQDWIRRRFE--APRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEG 2230
++ EQ+ WI RR E ++ + ++K++L +RL + E +L K+ +KRF LEG
Sbjct: 166 ISEFEQRQWIYRRLENVGGKIASNATNRKRIL-ERLTAAEGLERYLHTKYVGQKRFSLEG 224
Query: 2229 CEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEPADE 2053
+ LIP M ++ + V V+GM HRGRLNVL N + + +F E A
Sbjct: 225 GDALIPLMDTLVRQAGNNDVKDIVVGMAHRGRLNVLVNTLGKNPRKLFDEFEGKFEHAHH 284
Query: 2052 G---SGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEK 1882
+GDVKYH+G + + K V +A+ NPSHLE VDPVV G VR+ GD +
Sbjct: 285 DRAHTGDVKYHMGFSAD-IAVSDGKQVHLALAFNPSHLEIVDPVVAGSVRSRQERFGDTE 343
Query: 1881 CDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRS-SRSS 1705
+ IL+HGDAAFAGQGVV+E + + G +H+++NNQIGFTT R +RS+
Sbjct: 344 RKTVLPILIHGDAAFAGQGVVMELLQMSQARGFAVGGTLHVIINNQIGFTTSARDDARST 403
Query: 1704 PYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDE 1525
PYCTDV +++G P+FHVN DDP+AV+ V +A ++R+ FKKDV++DLVCYRR GHNE DE
Sbjct: 404 PYCTDVAKMIGAPVFHVNGDDPDAVVFVAQLAYEFRQQFKKDVVIDLVCYRRWGHNEADE 463
Query: 1524 PMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTY 1345
P TQP+MYQ I++ KT E Y K+ EGV K + Y + L+ + +
Sbjct: 464 PAATQPVMYQTIRKHKTTRELYATKLEGEGVIAAGEAKAMVDDYRAKLDSGKFTTELAS- 522
Query: 1344 VRNRDWLDSPWDDFF--KKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLK 1171
++ D W + K D +K T + P LH + + +
Sbjct: 523 -KHTDEFVIDWSKYLSGKLEDTVK---TSVKRQTLNKLAALINTIPPTVELHPRVAKIYE 578
Query: 1170 GRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKI 994
R +M + DW E LA+ +LL EG +RL GQD RGTF HRH +LHDQK D
Sbjct: 579 DRIKMAAGEQPCDWGFAENLAYATLLAEGHKLRLVGQDAGRGTFFHRHAILHDQKTDS-Y 637
Query: 993 YNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIID 814
Y PL+ L + TV +S LSE AV+GFE GYS DPN+L IWEAQFGDF+N AQ +ID
Sbjct: 638 YLPLHQLVSNPDDATVIDSLLSEEAVMGFEYGYSTTDPNTLCIWEAQFGDFANGAQVVID 697
Query: 813 QFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTF 634
QFI++G+ KW R SGL + LPHGYEG GPEHSSAR ERFLQ+C A E
Sbjct: 698 QFIAAGEVKWGRISGLSLFLPHGYEGQGPEHSSARLERFLQLC-----------ALE--- 743
Query: 633 EAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQS 454
N +V TTPA +H++RRQ+ M RKP +V +PKSLLRH +A S +++ +
Sbjct: 744 --------NMLVCVPTTPAQAFHMIRRQMRMSTRKPLIVMTPKSLLRHKLAVSTLDELAN 795
Query: 453 GSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFP 274
G FQ +IP+ A +P VKR+V C GKVYYD+ + +NDVA++R+EQL PFP
Sbjct: 796 G-KFQHIIPDDAA---DPKHVKRIVMCAGKVYYDLF-ENQQKRSQNDVAIIRIEQLYPFP 850
Query: 273 YDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPA 97
L+ E +++ A +++W QEE +N GAW ++ + ++L+ + YAGR S SPA
Sbjct: 851 RALLASELKRFNKATDVVWCQEEPQNQGAWYQIKHHLQAVLA-HAQRLHYAGRSSSPSPA 909
Query: 96 TGNKFTHMQEQKEMMS 49
G+ HM EQ+ +++
Sbjct: 910 VGHMAEHMAEQESLVA 925
>gi|46133589|ref|ZP_00157430.2| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Haemophilus influenzae R2866]
Length = 935
Score = 666 bits (1718), Expect = 0.0
Identities = 387/979 (39%), Positives = 549/979 (55%), Gaps = 17/979 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G++ YIE++YE++L DP SV SW F ++ A
Sbjct: 16 LGGANQSYIEELYESYLSDPQSVEESWRKTFDSLPKTTALEQPHTPVRDYFRRLARENHN 75
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 2578
A V +A A + K+ I +Y+ RGH A+LDPL +
Sbjct: 76 EAVTVIDPAAGAKLV-------------KVLQFINAYRFRGHLEANLDPLNYYRWKVSSV 122
Query: 2577 IPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLN 2398
PEL+ +G E+DL+ F + ++ ++ ++ L E+ Q LK+ YC S G+E+MH+
Sbjct: 123 --PELDYRHHGFTEQDLNETFNI--NHYVYKRDTIKLGELAQMLKETYCGSIGLEFMHVQ 178
Query: 2397 NLEQQDWIRRRFEAPRVTELSHDQKKVLFKR-LIRSTKFEEFLAKKWPSEKRFGLEGCEV 2221
++EQ+ W++ + E+ + +++V F R L + E +L K+P KRF LEG +
Sbjct: 179 DMEQKMWLQSKMESLLDKPIFTSEERVNFLRELTAADGLERYLGAKFPGAKRFSLEGSDA 238
Query: 2220 LIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGD 2041
IP MK++I SS GV+ V+GM HRGRLN+L NV + + +F+ + + E +GD
Sbjct: 239 FIPLMKEIIRHSSRQGVNDVVMGMAHRGRLNMLVNVLGKKPENLFDEFAG-KHSSERTGD 297
Query: 2040 VKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAI 1861
VKYH G + K V + + NPSHLE V PVV+G VR+ D + + +AI
Sbjct: 298 VKYHQGFSSDFA--VDDKRVHLTLAFNPSHLEIVSPVVIGSVRSRQTRMNDTEHSKVLAI 355
Query: 1860 LLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDVG 1684
+HGD+A AGQGVV ET N+ + Y+ G I IV+NNQIGFTT +P +RS+ YCTD+
Sbjct: 356 TVHGDSAVAGQGVVQETLNMSNARGYSVGGTIRIVINNQIGFTTSNPNDTRSTEYCTDIA 415
Query: 1683 RVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPL 1504
+++ PI HVN DDPEAV +A ++R FK+D+ +DL+ YRRHGHNE DEP+ TQP+
Sbjct: 416 KMIQAPIIHVNGDDPEAVAFAARMAVEYRNLFKRDIFIDLISYRRHGHNEADEPLATQPM 475
Query: 1503 MYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTY------V 1342
MY IK+ T + Y +++++EGV E+ V E Y DA +N +V
Sbjct: 476 MYSIIKKHPTPRKVYADRLVSEGVMTEEQVTEMANDY----RDALDNGDRVVSEWREMDT 531
Query: 1341 RNRDWLD-------SPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLE 1183
DWL +P++ F + L L + +YPE H +E
Sbjct: 532 AKMDWLQYLNYDWTAPYESKFSQERFLTLAK-------------RVCEYPESLRAHPRVE 578
Query: 1182 RTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKV 1006
+ R+ M + + LDW E +A+ +LL EG++VRLSG+D RGTF HRH V+H+Q
Sbjct: 579 KIYNDRKAMYQGEKLLDWGMAETMAYATLLDEGVNVRLSGEDAGRGTFFHRHAVVHNQN- 637
Query: 1005 DQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQ 826
D Y PL L QG + V +S LSE +VL FE GY+ DP +L IWEAQFGDF+N AQ
Sbjct: 638 DGTGYVPLTHLHANQGRFEVWDSVLSEESVLAFEYGYATTDPKTLTIWEAQFGDFANGAQ 697
Query: 825 CIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAF 646
+IDQFISSG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 698 IVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQ---------- 747
Query: 645 EGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVE 466
N V +TPA +YH+LRRQ R+P + SPKSLLRHP+A S ++
Sbjct: 748 ------------NMQVCVPSTPAQVYHMLRRQSLRKMRRPLIAISPKSLLRHPLAVSSLD 795
Query: 465 DFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQL 286
+ +G+ FQ VI E +P DVKRVV C+GKVYYD++ R+ + DVA++R+EQL
Sbjct: 796 ELINGT-FQTVIGE--IDELDPKDVKRVVMCSGKVYYDLLEQRR-ANNQKDVAIIRIEQL 851
Query: 285 SPFPYDLVQQECRKY-QGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPS 109
PFP++ V++ Y + +W QEE N GAW + S + + KYAGR S
Sbjct: 852 YPFPHEDVKKALEPYAHVTDYVWCQEEPLNQGAWYCSKHNFESAIP-ESVKLKYAGRPAS 910
Query: 108 SSPATGNKFTHMQEQKEMM 52
+SPA G H ++QK+++
Sbjct: 911 ASPAVGYMSLHTKQQKQLV 929
>gi|42521102|ref|NP_967017.1| 2-oxoglutarate dehydrogenase, E1
component [Wolbachia endosymbiont of Drosophila
melanogaster]
gi|42410843|gb|AAS14951.1| 2-oxoglutarate dehydrogenase, E1 component
[Wolbachia endosymbiont of Drosophila melanogaster]
Length = 884
Score = 665 bits (1717), Expect = 0.0
Identities = 393/985 (39%), Positives = 556/985 (55%), Gaps = 20/985 (2%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G ++ ++E+MY +LQ S+ W F + L V+
Sbjct: 7 LYGDNAEFVEEMYSRYLQGDKSIGEDWYRIF---------------------SSNLEVNK 45
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 2578
A T + T++D SV S+++ RSY GH ADL+PL N ++
Sbjct: 46 AE---TCGAQHVTKVDD--SVSSLAN------FFRSY---GHFFADLNPLLPN---VNKE 88
Query: 2577 IPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLN 2398
+ + + Y + + R DIYC + G E+MH++
Sbjct: 89 VDYQKYSNLYPASDAGIYR--------------------------DIYCKNIGFEFMHIS 122
Query: 2397 NLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVL 2218
+ E++ W++ + E T S D+K++L + LI S FE+FL K+P KRF +EG E
Sbjct: 123 SYEERMWLQEKIENQTYTLSSQDKKEIL-RHLIESEMFEQFLHMKFPGYKRFSIEGGESA 181
Query: 2217 IPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS---TLEPADEGS 2047
I A++++I S+ G++ V+GM HRGRLNVL V + A +LS+F E S
Sbjct: 182 IVAIEKIISDSTVFGIEEIVLGMAHRGRLNVLTKVMGKEYAAMLSEFQGNLAYPSGLEVS 241
Query: 2046 GDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTM 1867
GDVKYHLG +R K + +++ NPSHLEAV+PV+ G++RA+ + +
Sbjct: 242 GDVKYHLGYSSDRA-LSGGKKIHLSLCPNPSHLEAVNPVLAGRIRAK------QNIRSVL 294
Query: 1866 AILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDV 1687
I +HGDAAF GQGVV ET L ++ Y G +HIV+NNQ+GFT +P +RSS YCTD+
Sbjct: 295 GISIHGDAAFIGQGVVAETLTLSNIEGYKVDGIVHIVINNQVGFTANPCCARSSFYCTDI 354
Query: 1686 GRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQP 1507
+ + P+FHVN D+PEAV ++A ++R+ FKKDV++D++CYR++GHNE DEP FTQP
Sbjct: 355 AKSIEAPVFHVNGDNPEAVSFATSLAMEYRQKFKKDVVIDIMCYRKYGHNEGDEPNFTQP 414
Query: 1506 LMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDW 1327
LMY+ I + KT Y+EK+ E V + V + +++ + L+ + + T + DW
Sbjct: 415 LMYKAISKHKTPGTLYEEKLTAEKVLDGDEVNKLRSEFRAKLDKSLAESAAYT-PKKADW 473
Query: 1326 LDSPWDDFFKKR-------------DPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGL 1186
W + + P +L G S P FN++ +
Sbjct: 474 FGGVWSKLRRAKLNDLSEYYTDSGVPPDELKKLGVRIN---------SNIPSNFNINNKV 524
Query: 1185 ERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQK 1009
+ L GR + +++DWA E+LAF SLL E I VRLSGQD RGTFSHRH L DQ
Sbjct: 525 RKILDGRIDSINFGSNIDWATAESLAFASLLTERIGVRLSGQDSGRGTFSHRHSRLVDQ- 583
Query: 1008 VDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTA 829
V ++ + PLN+++E Q + V +S+LSEYAV+GFE GYS+ P SLV+WE QFGDF+N A
Sbjct: 584 VTEEAFIPLNNINEKQAHFEVIDSALSEYAVMGFEYGYSLDSPYSLVLWEGQFGDFANGA 643
Query: 828 QCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIA 649
Q +IDQFI+S ++KW+R SGLV+LLPHGYEG GPEHSSAR ERFLQ+C ED
Sbjct: 644 QIMIDQFIASAETKWLRSSGLVLLLPHGYEGQGPEHSSARIERFLQLCAED--------- 694
Query: 648 FEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPV 469
N V NC+TPAN +H+LRRQ+ FRKP VVF+PKSLLRH A S +
Sbjct: 695 -------------NMQVVNCSTPANYFHVLRRQMHRDFRKPLVVFTPKSLLRHKRAVSNL 741
Query: 468 EDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQ 289
DF+ F VIPE + +++VV C+GKVYYD+ A+ K ND+A++R+EQ
Sbjct: 742 SDFE--GKFLTVIPECRTGLVSNDKIRKVVICSGKVYYDICEAQ----KINDIAVIRLEQ 795
Query: 288 LSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLS---IDGRATKYAGR 118
PFP D + E KY+ AEI+W QEE KNMG W FV P I +LS I + K R
Sbjct: 796 FYPFPADKLSNELEKYKNAEIIWCQEEPKNMGGWFFVNPLIEEVLSNLDIQAKRPKCIAR 855
Query: 117 LPSSSPATGNKFTHMQEQKEMMSKV 43
++SPA G H Q+Q+E++ +V
Sbjct: 856 PAAASPACGYVSVHTQQQEEILKQV 880
>gi|21223647|ref|NP_629426.1| putative 2-oxoglutarate dehydrogenase
[Streptomyces coelicolor A3(2)]
gi|9909917|emb|CAC04496.1| putative 2-oxoglutarate dehydrogenase
[Streptomyces coelicolor A3(2)]
Length = 1272
Score = 665 bits (1717), Expect = 0.0
Identities = 387/885 (43%), Positives = 520/885 (58%), Gaps = 11/885 (1%)
Frame = -1
Query: 2661 LIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEK 2482
LI SY+ RGH +AD DPL + P+L+++ +GL DL+REF + + K
Sbjct: 430 LIHSYRVRGHVMADTDPL-----EYQQRKHPDLDITEHGLTLWDLEREFAVGG---FAGK 481
Query: 2481 KSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRL 2302
+ LR+IL L+D YC +TGVE+MH+ + +Q+ WI+ R E +Q ++L +RL
Sbjct: 482 SLMKLRDILGVLRDSYCRTTGVEFMHIQDPKQRKWIQDRIERSHTKPEREEQLRIL-RRL 540
Query: 2301 IRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVL 2122
+ FE FL K+ +KRF LEG E +IP + VIDS++ +D VIGM HRGRLNVL
Sbjct: 541 NAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVL 600
Query: 2121 ANVCRQPLATILSQFS-TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHL 1948
ANV + A I +F L+P GSGDVKYHLG + +K+++VANPSHL
Sbjct: 601 ANVVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGA-EGTFTGLDGEQIKVSLVANPSHL 659
Query: 1947 EAVDPVVMGKVRAEAFYAGDEKCDRT-MAILLHGDAAFAGQGVVLETFNLDDLPSYTTHG 1771
EAVDPV+ G RA+ D T + + +HGDAAFAGQGVV ET N+ L Y T G
Sbjct: 660 EAVDPVLEGVSRAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGG 719
Query: 1770 AIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKT 1591
+H+V+NNQ+GFT P SSRSS Y TDV R++ PIFHVN DDPEAV+ V +A ++R+
Sbjct: 720 TVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQA 779
Query: 1590 FKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVK 1411
F KDV++DL+CYRR GHNE D P FTQPLMY I + ++ + Y E ++ G + +
Sbjct: 780 FNKDVVIDLICYRRRGHNETDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAE 839
Query: 1410 EELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIG 1231
+ L Y LE + ++ P +F P+ + +T
Sbjct: 840 QALQDYQGQLEKVFTEVREAVSQPASAEPSEPQAEF-----PVAV-NTAITAETVKRIAE 893
Query: 1230 KFSQYPEGFNLHRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQR 1051
P+ +H L L+ R M++D ++DW GE LA GSLL +G+ VRL+GQD QR
Sbjct: 894 SQVNIPDHITVHPRLLPQLQRRAAMVEDGTIDWGMGETLAVGSLLLDGVPVRLTGQDSQR 953
Query: 1050 GTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSL 871
GTF RH V+ D++ + + PL LSE Q Y V NS LSEYAV+GFE GYS+ P++L
Sbjct: 954 GTFGQRHAVVIDRETGDE-FTPLLYLSEDQARYNVYNSLLSEYAVMGFEYGYSLARPDAL 1012
Query: 870 VIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQ 691
V+WEAQFGDF N AQ ++D+FISS + KW + SG+ +LLPHGYEG GP+HSSARPERFLQ
Sbjct: 1013 VMWEAQFGDFVNGAQTVVDEFISSAEQKWNQTSGVTLLLPHGYEGQGPDHSSARPERFLQ 1072
Query: 690 MCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFS 511
+C ++ N VA T P+N +HLLR QV P KP VVF+
Sbjct: 1073 LCAQN----------------------NMTVAMPTLPSNYFHLLRWQVHNPHHKPLVVFT 1110
Query: 510 PKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKH 331
PKS+LR A S E+F +G F+ VI G S +P VK+VVF GKVYYD+ A RK
Sbjct: 1111 PKSMLRLKAAASKAEEFTTG-QFRPVI---GDDSVDPAAVKKVVFTAGKVYYDLDAERKK 1166
Query: 330 VGKENDVALVRVEQLSPFPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLL 154
G D A++R+E+L P P +Q E KY AE LWAQEE N GAW F+ + L
Sbjct: 1167 RGL-TDTAIIRIERLYPLPGAELQAEIAKYPNAEKYLWAQEEPANQGAWPFIALNLIDHL 1225
Query: 153 SI-------DGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVF 40
+ G + R SSPA G+ H EQ++++ +VF
Sbjct: 1226 DLAVGADVPHGERLRRISRPHGSSPAVGSAKRHQAEQEQLVREVF 1270
Score = 35.4 bits (80), Expect = 8.5
Identities = 28/112 (25%), Positives = 44/112 (39%)
Frame = -1
Query: 3024 SSGKSHISASTLVQHRNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYF 2845
S S IS T A K+ G++ ++++Y+ +LQDP+SV +W +F
Sbjct: 5 SPSNSSISTDT------DQAGTAGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFF 58
Query: 2844 RNVEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQS 2689
+ + A G P A T +APA R A Q+
Sbjct: 59 ADYKPGAAATPT-----------AAGTVPTDAGSTPPAAPAPRAQAPAQPQA 99
>gi|15602142|ref|NP_245214.1| SucA [Pasteurella multocida Pm70]
gi|12720508|gb|AAK02361.1| SucA [Pasteurella multocida subsp.
multocida str. Pm70]
Length = 931
Score = 664 bits (1714), Expect = 0.0
Identities = 386/974 (39%), Positives = 550/974 (55%), Gaps = 10/974 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAG-ALGVS 2761
L G++ YIE++YE +L+DP SV SW F + + A S
Sbjct: 16 LGGTNQSYIEELYEDYLRDPDSVDASWQTIFNALPKSHTAVEQPHSQVRDYFKRLARDNS 75
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDD 2581
P V +D N S + + K+ + +++ RGH ADLDPL + +D
Sbjct: 76 PNGVSV---------IDPNVSARLV----KLLAYVNAHRNRGHLHADLDPLNLWQR-MD- 120
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
P L+ ++G E DLD F L ++ + ++LRE+ L+ YC + G+E+MH+
Sbjct: 121 --APTLDYKYHGFTESDLDETFDLGGE--VAHRNQISLRELQDLLQKTYCGTIGLEFMHV 176
Query: 2400 NNLEQQDWIRRRFEAPRVTELSHDQKKVLF-KRLIRSTKFEEFLAKKWPSEKRFGLEGCE 2224
N++E + W++ + E+ RVT+ + ++++ F + L + E +L K+P KRF LEG +
Sbjct: 177 NDVEARTWLQNKLES-RVTQGFNKEEQLKFLEELTAADGLERYLGAKFPGAKRFSLEGSD 235
Query: 2223 VLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSG 2044
I MK+++ G+D +GM HRGRLN+L NV + + + +F+ + G+G
Sbjct: 236 SFILLMKEIVRHGKRNGIDEIAMGMAHRGRLNMLVNVLGKKPSELFDEFAGKHNGN-GTG 294
Query: 2043 DVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMA 1864
DVKYH G + + V + + NPSHLE V PVV+G VRA D + + +
Sbjct: 295 DVKYHQGFSSDFMTDDGI--VHLVLAFNPSHLEIVSPVVIGSVRARQKRINDHEKAKVLP 352
Query: 1863 ILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDV 1687
+ +HGD+A GQGVV ET N+ Y+ G I IV+NNQIGFTT +P +RS+ YCTD+
Sbjct: 353 VTVHGDSAVIGQGVVQETLNMSGTRGYSVGGTIRIVINNQIGFTTSNPHDTRSTEYCTDI 412
Query: 1686 GRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQP 1507
+++ P+ HVN DDPEAV + +A ++R FK+D+ +DLV YRRHGHNE DEP TQP
Sbjct: 413 AKMIEAPVIHVNGDDPEAVAYAARMAVEYRTLFKRDIFIDLVSYRRHGHNEADEPSATQP 472
Query: 1506 LMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILE--DAYENAQKVTYVRNR 1333
LMY RIK+ T + Y ++++ +GV NE+ E + Y L+ D + + +
Sbjct: 473 LMYDRIKKHPTPRKVYADRLIAQGVINEEAATELVNNYRDALDRGDCVVAEWREMDLTTK 532
Query: 1332 DW---LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQ 1162
DW L W ++ K D + K +YP LH + + R
Sbjct: 533 DWTKYLSREWCEYESKFDAARFKGLAQ----------KVCEYPAQHELHSRVNKIYADRT 582
Query: 1161 QMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNP 985
M + LDW E +A+ +LL EG HVRLSG+D RGTF HRH VLH+QK D +Y P
Sbjct: 583 LMANGEKLLDWGMAETMAYATLLDEGYHVRLSGEDAGRGTFFHRHSVLHNQK-DATLYIP 641
Query: 984 LNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFI 805
L +L QG + V +S L+E AVL FE GY+ DP +L IWEAQFGDF+N AQ ++DQFI
Sbjct: 642 LANLHGSQGRFEVWDSVLTENAVLAFEYGYATTDPKTLTIWEAQFGDFANCAQVVVDQFI 701
Query: 804 SSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQ 625
SSG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C AQ
Sbjct: 702 SSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLC------------------AQ 743
Query: 624 QLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSN 445
Q N V +TPA IYHLLRRQ+ R+P VV SPKSLLRHP+A S +E+ G
Sbjct: 744 Q----NMQVCVPSTPAQIYHLLRRQMIRKVRRPLVVISPKSLLRHPLAVSTMEELIDG-K 798
Query: 444 FQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDL 265
FQ VIPE A +P V+RVV C+GKVYYD++ R+ ++DVA++R+EQL P+P++
Sbjct: 799 FQNVIPEVDA--LDPKHVRRVVMCSGKVYYDLLEQRRK-NNQSDVAIIRIEQLYPYPHEE 855
Query: 264 VQQECRKYQG-AEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGN 88
++Q Y + +W QEE N GAW Q S + G+ +Y GR S+SPA G
Sbjct: 856 MKQILADYSHVTDYVWCQEEPLNQGAWYCSQHNFVSSIPEHGK-LRYVGRPASASPAVGY 914
Query: 87 KFTHMQEQKEMMSK 46
H ++Q ++++
Sbjct: 915 MSLHNEQQTALVNE 928
>gi|22996772|ref|ZP_00041017.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Xylella fastidiosa Ann-1]
Length = 963
Score = 663 bits (1711), Expect = 0.0
Identities = 394/976 (40%), Positives = 552/976 (56%), Gaps = 13/976 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G ++ YIE +YE +L P+SV W AYF + AG + S
Sbjct: 39 LAGGNAAYIEDLYEQYLVLPNSVDPKWKAYFDGFKGRD--------------AGDIPHSA 84
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLK--IQLLIRSYQTRGHNIADLDPLGINSADLD 2584
A +T ++ + + Q SD + I LI +Y++RGH A +DPL +
Sbjct: 85 VIAHITDTAKQSIK-------QGASDERERNIGRLITAYRSRGHLGARIDPLALTPP--- 134
Query: 2583 DTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMH 2404
+ PP+L+L F+ L + DLD EF T I + + LR +L LK Y + G E+MH
Sbjct: 135 -SNPPDLDLPFHNLSQADLDNEF---STGGIGGQPRMKLRNLLAHLKATYTDTIGTEFMH 190
Query: 2403 LNNLEQQDWIRRRFE--APRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEG 2230
++ EQ+ WI RR E ++ + ++K++L +RL + E +L K+ +KRF LEG
Sbjct: 191 ISEFEQRQWIYRRLENVGGKIASNATNRKRIL-ERLTAAEGLERYLHTKYVGQKRFSLEG 249
Query: 2229 CEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEPADE 2053
+ LIP M ++ + + V V+GM HRGRLNVL N + + +F E A
Sbjct: 250 GDALIPLMDTLVRQAGSNDVKDIVVGMAHRGRLNVLVNTLGKNPRKLFDEFEGKFEHAHH 309
Query: 2052 G---SGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEK 1882
+GDVKYH+G + + K V +A+ NPSHLE VDPVV G VR+ GD +
Sbjct: 310 DRAHTGDVKYHMGFSAD-IAVGDGKQVHLALAFNPSHLEIVDPVVAGSVRSRQERFGDIE 368
Query: 1881 CDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRS-SRSS 1705
+ IL+HGDAAFAGQGVV+E + + G +H+++NNQIGFTT R +RS+
Sbjct: 369 RKTVLPILIHGDAAFAGQGVVMELLQMSQARGFAVGGTLHVIINNQIGFTTSARDDARST 428
Query: 1704 PYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDE 1525
PYCTDV +++G P+FHVN DDP+AV+ V +A ++R+ FKKDV++DLVCYRR GHNE DE
Sbjct: 429 PYCTDVAKMIGAPVFHVNGDDPDAVVFVAQLAYEFRQQFKKDVVIDLVCYRRWGHNEADE 488
Query: 1524 PMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTY 1345
P TQP+MYQ I++ KT E Y K+ EGV K + Y + L+ + +
Sbjct: 489 PAATQPVMYQTIRKHKTTRELYATKLEGEGVIAAGEAKAMVDDYRAKLDSGKFTTELAS- 547
Query: 1344 VRNRDWLDSPWDDFF--KKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLK 1171
++ D W + K D +K T + P LH + + +
Sbjct: 548 -KHTDEFVIDWSKYLSGKLEDTVK---TSVKRQTLNKLAALINTIPPTVELHPRVAKIYE 603
Query: 1170 GRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKI 994
R +M + DW E LA+ +LL EG +RL GQD RGTF HRH +LHDQK D
Sbjct: 604 DRIKMAAGEQPCDWGFAENLAYATLLAEGHKLRLVGQDAGRGTFFHRHAILHDQKTDS-Y 662
Query: 993 YNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIID 814
Y PL L + TV +S LSE AV+GFE GYS DPN+L IWEAQFGDF+N AQ +ID
Sbjct: 663 YLPLRQLVSNPDDATVIDSLLSEEAVMGFEYGYSTTDPNTLCIWEAQFGDFANGAQVVID 722
Query: 813 QFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTF 634
QFI++G+ KW R SGL + LPHGYEG GPEHSSAR ERFLQ+C A E
Sbjct: 723 QFIAAGEVKWGRISGLSLFLPHGYEGQGPEHSSARLERFLQLC-----------ALE--- 768
Query: 633 EAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQS 454
N +V TTPA +H++RRQ+ M RKP VV +PKSLLRH +A S +++ +
Sbjct: 769 --------NMLVCVPTTPAQAFHMIRRQMRMSTRKPLVVMTPKSLLRHKLAVSTLDELAN 820
Query: 453 GSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFP 274
G FQ +IP+ A +P VKR+V C GKVYYD + + +NDVA++R+EQL PFP
Sbjct: 821 G-KFQHIIPDDAA---DPKHVKRIVMCAGKVYYD-IFENQQKRSQNDVAIIRIEQLYPFP 875
Query: 273 YDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPA 97
L+ E +++ A +++W QEE +N GAW ++ + ++L+ + YAGR S SPA
Sbjct: 876 RALLASELKRFNKATDVVWCQEEPQNQGAWYQIKHHLQAVLA-HAQRLHYAGRSSSPSPA 934
Query: 96 TGNKFTHMQEQKEMMS 49
G+ HM EQ+ +++
Sbjct: 935 VGHMAEHMAEQESLVA 950
>gi|46364406|ref|ZP_00227025.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Kineococcus radiotolerans SRS30216]
Length = 1287
Score = 660 bits (1704), Expect = 0.0
Identities = 384/895 (42%), Positives = 530/895 (58%), Gaps = 12/895 (1%)
Frame = -1
Query: 2688 ISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLL 2509
I+ ++ LI +Y+ RGH +AD DPL + + P+LE+ +GL DLDREF
Sbjct: 433 INKTARVVELIHAYRVRGHLMADTDPL-----EYRQRVHPDLEIETHGLTLWDLDREF-- 485
Query: 2508 PPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHD 2329
PT K + LR++L L+D YC + G+EYMH+ +Q+ WI+ R E P +
Sbjct: 486 -PTGGFGGKAHMKLRDVLGVLRDSYCRTVGIEYMHIQEPDQRRWIQDRVERPYAKPSAAV 544
Query: 2328 QKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGM 2149
Q ++L +RL + FE FL K+ +KRF LEG E +I + ++ ++T G+D +GM
Sbjct: 545 QLRIL-RRLNAAEAFETFLQTKYVGQKRFSLEGGESVIALLDALLSRAATNGMDEVCLGM 603
Query: 2148 PHRGRLNVLANVCRQPLATILSQFSTLEPAD--EGSGDVKYHLGVCIERLNRQSQKNVKI 1975
HRGRLNVL N+ + + + +F ++ +GSGDVKYHLG + + K+
Sbjct: 604 AHRGRLNVLTNIAGKSYSQVFREFEGMQDPRTVQGSGDVKYHLGT-EGTFTGEDGEQTKV 662
Query: 1974 AVVANPSHLEAVDPVVMGKVRAEAF---YAGDEKCDRTMAILLHGDAAFAGQGVVLETFN 1804
V ANPSHLEAVDPV+ G RA+ AG K + +LLHGDAAFAGQGVV ET N
Sbjct: 663 YVAANPSHLEAVDPVLEGVARAKQDRINMAG--KSFPVLPVLLHGDAAFAGQGVVAETLN 720
Query: 1803 LDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMH 1624
L L Y T G++H+V+NNQ+GFTT P SSRSS YCTDVGR++ PIFHVN DDPEA +
Sbjct: 721 LSQLRGYRTGGSVHVVINNQVGFTTAPASSRSSVYCTDVGRMIQAPIFHVNGDDPEACVR 780
Query: 1623 VCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKIL 1444
V +A ++R+ F+KDV++D+VCYRR GHNE D+P TQPLMY I++ ++ + Y E+++
Sbjct: 781 VAQLAFEFRQAFEKDVVIDMVCYRRRGHNEGDDPSMTQPLMYNLIEKKRSVRKSYTEQLI 840
Query: 1443 NEGVANEQYVKEELTKYGSILEDAY----ENAQKVTYVRNRDWLDSPWDDFFKKRDPLKL 1276
G + + +E L Y + LE A+ E+ +R L+ P ++ P +
Sbjct: 841 GRGDISVEEAEEALRDYSAQLERAFAETKESKSGPVDGDSRGGLERPAAQEADEQTPART 900
Query: 1275 PSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKDNSLDWACGEALAFGSLL 1096
T + P+GF +H L + L R QM D +DW GE LAFGSLL
Sbjct: 901 HPTAVDASVLQHIGQVQATPPQGFTVHPKLRQLLDKRAQMSTDGGIDWGWGELLAFGSLL 960
Query: 1095 KEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLS-EG--QGEYTVCNSSLSE 925
EG VRL+GQD +RGTF RH VL D +V + PL L EG Q ++ + +S LSE
Sbjct: 961 MEGTPVRLAGQDSRRGTFVSRHAVLTD-RVTGDEWTPLLYLGREGAEQAKFWIYDSLLSE 1019
Query: 924 YAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHG 745
YA +GFE GYS+ P++LV+WEAQFGDF N AQ +ID+FI +G+ KW ++S +V+LLPHG
Sbjct: 1020 YAAMGFEYGYSVERPDALVLWEAQFGDFFNGAQTVIDEFIVAGEQKWGQRSSVVLLLPHG 1079
Query: 744 YEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYH 565
YEG GP+HSS R ERFLQMC ED N VA +TPA+ +H
Sbjct: 1080 YEGQGPDHSSGRIERFLQMCAED----------------------NMTVAVPSTPASYFH 1117
Query: 564 LLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKR 385
LLRRQ RKP VVF+PKS+LR A+S VEDF +G+ F+ V+ + G + V R
Sbjct: 1118 LLRRQAYARPRKPLVVFTPKSMLRLKAAQSAVEDFTTGT-FREVVGDQGGLDASA--VTR 1174
Query: 384 VVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEH 205
V+ C+GKVY+D+VA R G + A+VR+EQL+P P + V E +Y GAE +W QEE
Sbjct: 1175 VLLCSGKVYWDLVAERAARG-DTTTAVVRLEQLAPLPVEQVLAELGRYPGAEAVWVQEEP 1233
Query: 204 KNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVF 40
N G W V L + + R S+SPA G+ H EQ++++ + F
Sbjct: 1234 ANQGGWWHV---AMGLFPVLNAKLRLVSRPASASPAAGSAKRHQAEQRQIVEEAF 1285
>gi|15676848|ref|NP_273993.1| 2-oxoglutarate dehydrogenase, E1
component [Neisseria meningitidis MC58]
gi|15794095|ref|NP_283917.1| putative 2-oxoglutarate dehydrogenase E1
component [Neisseria meningitidis Z2491]
gi|11252292|pir||C81139 probable oxoglutarate dehydrogenase
(lipoamide) (EC 1.2.4.2) E1 component NMA1149 [imported]
- Neisseria meningitidis (strain MC58 serogroup B,
strain Z2491 serogroup A)
gi|7226194|gb|AAF41361.1| 2-oxoglutarate dehydrogenase, E1 component
[Neisseria meningitidis MC58]
gi|7379842|emb|CAB84411.1| putative 2-oxoglutarate dehydrogenase E1
component [Neisseria meningitidis Z2491]
Length = 942
Score = 659 bits (1701), Expect = 0.0
Identities = 387/980 (39%), Positives = 553/980 (55%), Gaps = 17/980 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L GS++ YIE++YEA+L++P +V W YF ++ G + V
Sbjct: 10 YLFGSNAPYIEELYEAFLENPDAVDEKWKQYFTDLSKQ---------------PGTVAVD 54
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDH--LKIQL----LIRSYQTRGHNIADLDPLGIN 2599
A + S + ++V +D LK Q+ LI +Y+ +G A LDPL
Sbjct: 55 VAHTPIRESFVTLAKKKIASAVAGGADEAMLKKQVSVLRLISAYRIQGVGAAQLDPL--- 111
Query: 2598 SADLDDTIPPE----LELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYC 2431
IPP L+ F+GL + D+ +F + F + K L L +I+ LK YC
Sbjct: 112 -----KRIPPRDIEALDPKFHGLSDADMALQFNMGEGDFANRGK-LPLSQIISNLKQTYC 165
Query: 2430 TSTGVEYMHLNNLEQQDWIRRRFEAPRVT-ELSHDQKKVLFKRLIRSTKFEEFLAKKWPS 2254
+EY+++ N E++ W+R FE+ T + DQK+ + K + + E +L K+
Sbjct: 166 GHIALEYIYIPNTEERRWVRNYFESVLSTPHYNADQKRRILKEMTAAETLERYLHTKYVG 225
Query: 2253 EKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS 2074
+KRFG+EG E I + +I ++ GV+ +IGM HRGRLNVL N+ + + ++F
Sbjct: 226 QKRFGVEGGESAIAGLNYLIQNAGKDGVEEVIIGMAHRGRLNVLVNILGKKPGDLFAEFE 285
Query: 2073 TLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYA 1894
SGDVKYH+G + +V +A NPSHLE V+PVV G RA+
Sbjct: 286 GRAEIKLPSGDVKYHMGFSSDIATPHGPMHVSLAF--NPSHLEIVNPVVEGSARAKQKRL 343
Query: 1893 GDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRS 1717
G+ D+ + +L+HGD+AF G GV TFNL YTT G +HIV+NNQIGFTT D R
Sbjct: 344 GENGRDKVLPVLIHGDSAFIGLGVNQATFNLSKTRGYTTGGTVHIVINNQIGFTTSDIRD 403
Query: 1716 SRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHN 1537
+RS+ +CTD+ ++V P+ HVN DDPE V A D+RK F KD+++D+VCYR+ GHN
Sbjct: 404 TRSTVHCTDIAKMVSAPVIHVNGDDPERVCFAIQAALDYRKKFHKDIVIDVVCYRKWGHN 463
Query: 1536 ELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQ 1357
E D+P TQP+MY+++ Q A Y E+++ EGV + + Y L D E+ +
Sbjct: 464 EGDDPTLTQPMMYKKVSQHPGARALYTEQLIAEGVVTQAEADGYIQAYRDAL-DKGEHVE 522
Query: 1356 KVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERT 1177
+ T + N W + + +D + TG KF+ PEGF LH +R
Sbjct: 523 QTT-LSNFQRTQIDWSKY-QGKDWREHIETGLPAADIERLTEKFTAVPEGFALHPTAKRV 580
Query: 1176 LKGRQQMLKDN-SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKV-- 1006
++ R+ M ++DW E LA+ SL+ +G VR+SG+D RGTFSHRH VLHDQK
Sbjct: 581 IEARKAMASGKQAIDWGMAETLAYASLVTKGHGVRISGEDSGRGTFSHRHAVLHDQKREK 640
Query: 1005 -DQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTA 829
D Y PL + EG GE+ V +S L+E AV+ FE G++ P+ L IWEAQFGDF+N A
Sbjct: 641 WDDGTYVPLRHMGEGMGEFLVIDSILNEEAVMAFEYGFACSAPDKLTIWEAQFGDFANGA 700
Query: 828 QCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIA 649
Q IDQF+SSG++KW R GL +LPHGY+G GPEHSSAR ER+LQ+C+E+
Sbjct: 701 QVTIDQFLSSGETKWGRLCGLTTILPHGYDGQGPEHSSARVERWLQLCSEN--------- 751
Query: 648 FEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPV 469
N V + + ++HLL+RQV +RKP V+F K LLR A SP+
Sbjct: 752 -------------NMQVIMPSEASQMFHLLQRQVLGSYRKPLVIFMSKRLLRFKGAMSPL 798
Query: 468 EDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQ 289
E+F GS F+ VI +T + N VKRVV C G+VYYD+ A R E+DVA+VRVEQ
Sbjct: 799 ENFTEGSTFRPVIGDTAERASN-DSVKRVVLCAGQVYYDLEAGRAERKLEDDVAIVRVEQ 857
Query: 288 LSPFPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLP 112
L PFPYD V+ E KY A+ ++WAQEE KN GA+ ++ RI ++S + + YAGR
Sbjct: 858 LYPFPYDEVKAELAKYPNAKSVVWAQEEPKNQGAFYQIRHRIEDVIS-EEQKLSYAGRPS 916
Query: 111 SSSPATGNKFTHMQEQKEMM 52
S+SPA G H+ + K+++
Sbjct: 917 SASPAVGYSSKHIAQLKQLV 936
>gi|15892150|ref|NP_359864.1| 2-oxoglutarate dehydrogenase e1
component [EC:1.2.4.2] [Rickettsia conorii str. Malish 7]
gi|32129823|sp|Q92J42|ODO1_RICCN 2-oxoglutarate dehydrogenase E1
component (Alpha-ketoglutarate dehydrogenase)
gi|25284470|pir||C97728 hypothetical protein sucA [imported] -
Rickettsia conorii (strain Malish 7)
gi|15619280|gb|AAL02765.1| 2-oxoglutarate dehydrogenase e1 component
[EC:1.2.4.2] [Rickettsia conorii str. Malish 7]
Length = 928
Score = 659 bits (1700), Expect = 0.0
Identities = 372/980 (37%), Positives = 550/980 (55%), Gaps = 7/980 (0%)
Frame = -1
Query: 2952 KHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGA 2773
K +L G +++++E++Y+ +L +P+SV +W +F ++
Sbjct: 6 KKTGYLFGGNAVFVEELYKQYLANPASVDQTWQEFFAGIKDN----------------NT 49
Query: 2772 LGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSA 2593
L A + L+ N S + ++ LK + +I +Y+ H +A+LDPLG+
Sbjct: 50 LLNKSTAKIIIPDEIKKESLNNNLSSEDLNS-LKAKEMINAYRKHAHYLANLDPLGLELR 108
Query: 2592 DLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVE 2413
+ + +L + +GL L+ + T + L E++ + +Y S GVE
Sbjct: 109 KTKNDL--KLNIETFGLDSGQLEENINI--TDEFVGTWNCKLSELVTKFDKVYTGSIGVE 164
Query: 2412 YMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLE 2233
+ + N+ ++W+ + E+ S + KK + L+ FE++L K+P KRF +E
Sbjct: 165 FEQIENVAGKNWLYNKLESE--VTFSSEDKKTILNDLVEVEGFEQYLHTKFPGAKRFSIE 222
Query: 2232 GCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQF---STLEP 2062
G + I AM + ID S GV VIGM HRGRLN L V +P +++ F S
Sbjct: 223 GGDASIVAMSKAIDLSMHQGVSEIVIGMAHRGRLNTLTKVVGKPYKAVIADFISGSVFPD 282
Query: 2061 ADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEK 1882
SGDVKYHLG +R K + +++ NPSHLEAV+P+V GKVRA+ GD K
Sbjct: 283 ELNVSGDVKYHLGYSSDRT--LEDKKIHLSLADNPSHLEAVNPIVAGKVRAKQDILGDTK 340
Query: 1881 CDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSP 1702
+ AIL+HGDAAF GQGVV E+ ++ L +Y G +H V+NNQ+GFT + +R+S
Sbjct: 341 RSKVKAILVHGDAAFCGQGVVAESLSMSPLAAYDIGGILHFVINNQLGFTANAADTRASR 400
Query: 1701 YCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEP 1522
Y T+ +++ PI HVN DD EAV+ N+A ++R+ F KDV+V+++CYR++GHNE DEP
Sbjct: 401 YSTEFAKIIAAPILHVNGDDIEAVLKATNIAVEYRQKFGKDVVVEIICYRKYGHNEGDEP 460
Query: 1521 MFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYV 1342
M+TQ MY IK T Y +++ GV + Y + ++ + L+ YE A+ +Y
Sbjct: 461 MYTQGKMYNIIKNKLTPGNIYANELVKSGVIDNNYFAKLKEEFKAKLDKEYEQAK--SYK 518
Query: 1341 RNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQ 1162
+ +L W + R + TG K + P+ F ++ L + + R+
Sbjct: 519 QEAHFLGGLWQGISRTRTQATI--TGISKKTLHDLGTKLCEIPKDFAVNPKLVKLFEARK 576
Query: 1161 QML-KDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNP 985
L D +DWA E LAF SLL G ++RL+GQD RGTFSHRH VLH+Q +D Y P
Sbjct: 577 ATLTADQPIDWATAEQLAFASLLASGTNIRLTGQDSGRGTFSHRHSVLHNQ-IDGTTYIP 635
Query: 984 LNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFI 805
LN+LS+ Q +Y V +S+LSEYAVLGFE GYS+ +P +LV+WEAQFGDF+N AQ I DQFI
Sbjct: 636 LNNLSKEQAKYEVADSNLSEYAVLGFEYGYSLANPKNLVLWEAQFGDFANGAQIIFDQFI 695
Query: 804 SSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQ 625
SS ++KW+R SGLV+LLPH +EG GPEHSSAR ERFLQ+ E+
Sbjct: 696 SSSETKWLRMSGLVVLLPHAFEGQGPEHSSARLERFLQLAAEN----------------- 738
Query: 624 QLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSN 445
N V TTPA+I+HLLRRQ+ RKP +V SPKSLLRH A S +++ +
Sbjct: 739 -----NMYVTYPTTPASIFHLLRRQILDDTRKPLIVMSPKSLLRHKYAVSKLDELGENTT 793
Query: 444 FQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDL 265
F V+ E N ++ +V+ C+GKVYYD+ R G +++A++R+EQL PF L
Sbjct: 794 FLPVLDEVTKVDTN--NITKVILCSGKVYYDLFEMR---GNNSNIAIIRLEQLYPFEKKL 848
Query: 264 VQQECRKY-QGAEILWAQEEHKNMGAWSFVQPRINSLLSIDG--RATKYAGRLPSSSPAT 94
V +KY + E +W QEE KNMG W ++ +N L G KY GR S+SPA
Sbjct: 849 VASLLKKYNRTQEFIWCQEEPKNMGTWCYIVSHLNDALKEAGIKNEFKYVGREESASPAV 908
Query: 93 GNKFTHMQEQKEMMSKVFGV 34
G+ H ++Q++++ G+
Sbjct: 909 GSLQVHNKQQEKLLRTALGI 928
>gi|34580820|ref|ZP_00142300.1| 2-oxoglutarate dehydrogenase e1
component [Rickettsia sibirica]
gi|28262205|gb|EAA25709.1| 2-oxoglutarate dehydrogenase e1 component
[Rickettsia sibirica 246]
Length = 928
Score = 659 bits (1699), Expect = 0.0
Identities = 371/980 (37%), Positives = 548/980 (55%), Gaps = 7/980 (0%)
Frame = -1
Query: 2952 KHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGA 2773
K +L G +++++E++Y+ +L +P+SV +W +F ++
Sbjct: 6 KTTDYLFGGNAVFVEELYKQYLANPASVDQTWQEFFAGIKDNNTLLNKSTVKI------- 58
Query: 2772 LGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSA 2593
+ L+ N S + ++ LK + +I +Y+ H +A+LDPLG+
Sbjct: 59 ---------IIPDEIKKESLNNNLSSEDLNS-LKAKEMINAYRKHAHYLANLDPLGLEPR 108
Query: 2592 DLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVE 2413
+ + +L + +GL L+ + T + L E++ + +Y S GVE
Sbjct: 109 KTKNDL--KLNIETFGLDSGQLEENINI--TDEFVGTWNCKLSELVTKFDKVYTGSIGVE 164
Query: 2412 YMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLE 2233
+ + N+ ++W+ + E+ S + KK + L+ FE++L K+P KRF +E
Sbjct: 165 FEQIENVAGKNWLYNKLESE--VTFSSEDKKTILNDLVEVEGFEQYLHTKFPGAKRFSIE 222
Query: 2232 GCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQF---STLEP 2062
G + I AM + ID S GV VIGM HRGRLN L V +P +++ F S
Sbjct: 223 GGDASIVAMSKAIDLSMHQGVSEIVIGMAHRGRLNTLTKVVGKPYKAVIAGFISGSVFPD 282
Query: 2061 ADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEK 1882
SGDVKYHLG +R K + +++ NPSHLEAV+P+V GKVRA+ GD K
Sbjct: 283 ELNVSGDVKYHLGYSSDRT--LEDKKIHLSLADNPSHLEAVNPIVAGKVRAKQDILGDTK 340
Query: 1881 CDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSP 1702
+ AIL+HGDAAF GQGVV E+ ++ L +Y G +H V+NNQ+GFT + +R+S
Sbjct: 341 RSKVKAILVHGDAAFCGQGVVAESLSMSPLAAYDIGGILHFVINNQLGFTANAADTRASR 400
Query: 1701 YCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEP 1522
Y T+ +++ PI HVN DD EAV+ N+A ++R+ F KDV+V+++CYR++GHNE DEP
Sbjct: 401 YSTEFAKIIAAPILHVNGDDIEAVLKATNIAVEYRQKFGKDVVVEIICYRKYGHNEGDEP 460
Query: 1521 MFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYV 1342
M+TQ MY IK T Y +++ GV + Y + ++ + L+ YE A+ +Y
Sbjct: 461 MYTQGKMYNIIKNKLTPGNIYANELVKSGVIDNNYFAKLKEEFKAKLDKEYEQAK--SYK 518
Query: 1341 RNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQ 1162
+ +L W + R + TG K + P+ F ++ L + + R+
Sbjct: 519 QEAHFLGGLWQGISRTRTQATI--TGISKKTLHDLGTKLCEIPKDFAVNPKLVKLFEARK 576
Query: 1161 QML-KDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNP 985
L D +DWA E LAF SLL G ++RL+GQD RGTFSHRH VLH+Q +D Y P
Sbjct: 577 ATLTADQPIDWATAEQLAFASLLASGTNIRLTGQDSGRGTFSHRHSVLHNQ-IDGTTYIP 635
Query: 984 LNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFI 805
LN+LS+ Q +Y V NS+LSEYAVLGFE GYS+ +P +LV+WEAQFGDF+N AQ I DQFI
Sbjct: 636 LNNLSKEQAKYEVTNSNLSEYAVLGFEYGYSLANPKNLVLWEAQFGDFANGAQIIFDQFI 695
Query: 804 SSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQ 625
SS ++KW+R SGLV+LLPH +EG GPEHSSAR ERFLQ+ E+
Sbjct: 696 SSSETKWLRMSGLVVLLPHAFEGQGPEHSSARLERFLQLAAEN----------------- 738
Query: 624 QLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSN 445
N V TTPA+I+HLLRRQ+ RKP +V SPKSLLRH A S +++ +
Sbjct: 739 -----NMYVTYPTTPASIFHLLRRQILDDTRKPLIVMSPKSLLRHKYAVSKLDELGENTT 793
Query: 444 FQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDL 265
F V+ E N ++ +V+ C+GKVYYD+ R G +++A++R+EQL PF L
Sbjct: 794 FLPVLDEVTKVDTN--NITKVILCSGKVYYDLFEMR---GNNSNIAIIRLEQLYPFEKKL 848
Query: 264 VQQECRKY-QGAEILWAQEEHKNMGAWSFVQPRINSLLSIDG--RATKYAGRLPSSSPAT 94
V +KY + E +W QEE KNMG W ++ +N L G KY GR S+SPA
Sbjct: 849 VASLLKKYNRTQEFIWCQEEPKNMGTWCYIVAHLNDALKEAGIKNEFKYVGREESASPAV 908
Query: 93 GNKFTHMQEQKEMMSKVFGV 34
G+ H ++Q++++ G+
Sbjct: 909 GSLQAHNKQQEKLLRTALGI 928
>gi|24373494|ref|NP_717537.1| 2-oxoglutarate dehydrogenase, E1
component [Shewanella oneidensis MR-1]
gi|24347794|gb|AAN54981.1| 2-oxoglutarate dehydrogenase, E1 component
[Shewanella oneidensis MR-1]
Length = 939
Score = 659 bits (1699), Expect = 0.0
Identities = 392/994 (39%), Positives = 556/994 (55%), Gaps = 18/994 (1%)
Frame = -1
Query: 2976 NQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRN---VEXXXXXXXXX 2806
+Q + A L+G++S Y+E+MYEA+ +DP SV W A F N V
Sbjct: 2 HQGIMKAWLESSHLSGANSTYVEEMYEAYQEDPQSVSDDWRAVFDNLPPVNGASKDAPEA 61
Query: 2805 XXXXXXAYAGAL---GVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRG 2635
Y +L G +AA+VT A ++ K+ LI +++ RG
Sbjct: 62 AHSKVRDYFRSLAMEGRHKSAARVTDPELDAKQV-------------KVLQLINAHRFRG 108
Query: 2634 HNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREIL 2455
H A+LDPL + + + P +F+GL + D++REF +F +++ L +++
Sbjct: 109 HQGANLDPLELWKREPVADLDP----AFHGLTKEDMEREF--NTGSFAHGGETMKLADLV 162
Query: 2454 QRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQ--KKVLFKRLIRSTKFE 2281
+ LK YC S G EYMH+ + +++ WI++R E P + + ++D+ K + + L + E
Sbjct: 163 KALKATYCGSIGAEYMHITDTDEKRWIQQRLE-PSLGKANYDKSVKTRILEGLNAAEGIE 221
Query: 2280 EFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQP 2101
++L K+P KRF LEG + L+P M+++I + G V+GM HRGRLNVL NV +
Sbjct: 222 KYLGAKFPGAKRFSLEGGDALVPMMREIIYRAGEAGTKEIVVGMAHRGRLNVLVNVLGKR 281
Query: 2100 LATILSQFSTLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMG 1921
A + +F+ GSGDVKYH G + NV +A+ NPSHLE V+PVVMG
Sbjct: 282 PAELFDEFAGKHADTHGSGDVKYHQGFSSDF--ETPGGNVHLALAFNPSHLEIVNPVVMG 339
Query: 1920 KVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQI 1741
VRA G + + M I +HGD+A GQG+V ETFN+ + G+I IVVNNQ+
Sbjct: 340 SVRARQDRRGCKDGLQVMPITIHGDSAITGQGIVQETFNMSQTRGFKVGGSIRIVVNNQV 399
Query: 1740 GFTTDPRSS-RSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDL 1564
GFTT RS+ YCTD+ ++V PIFHVN DDPEAV V +A D+R FK+DV++DL
Sbjct: 400 GFTTSNHYDVRSTEYCTDIAKMVQAPIFHVNSDDPEAVAFVAQLAVDYRNEFKRDVVIDL 459
Query: 1563 VCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSI 1384
VCYRRHGHNE DEP TQPLMY +IK+ T + Y +K++ E V + Y
Sbjct: 460 VCYRRHGHNEADEPSATQPLMYAKIKKHPTPRKIYADKLIAENTIAADDVTGMINTYRDA 519
Query: 1383 LE--DAYENAQKVTYVRNRDW---LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQ 1219
L+ D + + DW + WD+ + P++ K S
Sbjct: 520 LDQGDCVVKEWRPMTLHTVDWTPYIGREWDEAYDASLPIE---------RLQKLADKLSY 570
Query: 1218 YPEGFNLHRGLERTLKGRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTF 1042
PE +L + + R M K + LDW E LA+ ++L++ VR++GQD RGTF
Sbjct: 571 VPESHSLQSRVAKIYSDRVAMAKGEKPLDWGFAETLAYATILEDKQRVRITGQDSGRGTF 630
Query: 1041 SHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIW 862
HRH VLH+Q D Y PL ++S+GQG + +S LSE +VL FE GY+ +P+ L IW
Sbjct: 631 FHRHAVLHNQN-DATTYLPLRNISDGQGPIDITDSVLSEASVLAFEYGYATAEPSGLAIW 689
Query: 861 EAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCN 682
EAQFGDF+N AQ +IDQF+SSG+ KW R GL MLLPHGYEG GPEHSSAR ERFLQ+C
Sbjct: 690 EAQFGDFANCAQVVIDQFLSSGEQKWGRLCGLTMLLPHGYEGQGPEHSSARLERFLQLC- 748
Query: 681 EDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKS 502
+ N V +TPA +YH+LRRQV P R+P VV SPKS
Sbjct: 749 ---------------------ANHNMQVCVPSTPAQVYHMLRRQVVRPMRRPLVVMSPKS 787
Query: 501 LLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGK 322
LLRHP+A S +++ +GS FQ VI E + D RVVFC+GKVY++++ R+ K
Sbjct: 788 LLRHPLAVSSMDELANGS-FQNVIGEIDTLEASKVD--RVVFCSGKVYFELLEKRR---K 841
Query: 321 E--NDVALVRVEQLSPFPYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLS 151
E N++A++RVEQL PFP++ + YQ + +W QEE +N GAW Q + +
Sbjct: 842 ENINNIAIIRVEQLYPFPHEEMVAALADYQHVKDFVWCQEEPQNQGAWYSSQHHFWAAIP 901
Query: 150 IDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMS 49
+ T YAGR S++PA G H +Q+ +++
Sbjct: 902 AGAKLT-YAGREASAAPACGYPELHAHQQESLVN 934
>gi|48863228|ref|ZP_00317122.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Microbulbifer degradans 2-40]
Length = 953
Score = 658 bits (1697), Expect = 0.0
Identities = 384/994 (38%), Positives = 539/994 (53%), Gaps = 14/994 (1%)
Frame = -1
Query: 2988 VQHRNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNV-EXXXXXXX 2812
V +S+ + L+G ++ Y+E YE++L DP SV W YF +
Sbjct: 6 VGEMQESIMELLWKTSHLSGGNAAYVEDQYESYLSDPHSVSEEWRDYFDKLPRVNGSASE 65
Query: 2811 XXXXXXXXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGH 2632
Y LG + A + + V+ + L+ +Y+ GH
Sbjct: 66 DVNHSEIIKYFELLGKNRARPIIVPGAGSGDIAHERKQVEVVQ-------LVNAYRLSGH 118
Query: 2631 NIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQ 2452
A++DPL + + P +L+L F+ L DLD F F K L++I+
Sbjct: 119 QKANIDPLNLRAVKN----PVDLDLGFHRLNTADLDSVFQTGDLAF--GYKEAKLKDIIA 172
Query: 2451 RLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVT-ELSHDQKKVLFKRLIRSTKFEEF 2275
L+ YC + G E MH+ N E++ W+ R E R + K+ + +RL + E
Sbjct: 173 DLEKTYCGNIGAEVMHITNYEERRWLLNRLERSRSQPDFGPKAKRNILRRLTAAEGLERH 232
Query: 2274 LAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLA 2095
L K+P KRFGLEG E IP + +I G V+GM HRGRLN L N+ + +
Sbjct: 233 LDSKYPGTKRFGLEGGESFIPLLDALIRRVGEYGAKEMVLGMAHRGRLNALVNILGKNPS 292
Query: 2094 TILSQFSTLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKV 1915
+ +F + D SGDVKYH G + + ++ +A NPSHLE V PVV G V
Sbjct: 293 DLFDEFEGKKLVDT-SGDVKYHQGFSSNVMTPGGEMHLALAF--NPSHLEIVSPVVEGSV 349
Query: 1914 RAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGF 1735
RA GD+ + +++HGDAAFAGQGVV+ETF + +Y T G +H+V+NNQ+GF
Sbjct: 350 RARQDRRGDKDGHTVVPVVVHGDAAFAGQGVVMETFQMSQTRAYKTGGTVHLVINNQVGF 409
Query: 1734 TTDPRS-SRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVC 1558
TT +RS+ YCTDV +++ PIFHVN DDPEAV++V +AAD+R FKKDV++DLVC
Sbjct: 410 TTSRADDARSTAYCTDVAKMIETPIFHVNGDDPEAVVYVTQLAADYRNEFKKDVVIDLVC 469
Query: 1557 YRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILE 1378
YRR GHNE DEP TQPLMY+ I+ KT Y E+++N GV + + Y + L+
Sbjct: 470 YRRRGHNETDEPSSTQPLMYKAIRSHKTTRTVYAEQLVNAGVVTQDEADQMTNDYRAALD 529
Query: 1377 DAYENAQKVT-------YVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQ 1219
A+ + +V ++ W+ P+K + S
Sbjct: 530 RGEHVARGLVSEPDSSLFVNWSPYIGHDWNTPADTTYPIK---------ELQSLAEQTSH 580
Query: 1218 YPEGFNLHRGLERTLKGRQQMLKDN-SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTF 1042
P+G + R + + R++M ++W E LA+ +LLKEG +RL+GQDV RGTF
Sbjct: 581 VPDGVQVQRQVAKIYDDRRKMAGGALPINWGMAETLAYATLLKEGHKIRLTGQDVGRGTF 640
Query: 1041 SHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIW 862
SHRH V+H+QK + Y PL ++SE Q + +S LSE AVL FE GY+ P LVIW
Sbjct: 641 SHRHAVVHNQKTGEA-YIPLANISEDQAPLDIYDSLLSEEAVLAFEYGYATTSPKGLVIW 699
Query: 861 EAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCN 682
EAQFGDF+N AQ +IDQFI+SG+ KW R GL MLLPHGYEG GPEHSSAR ERF+Q+C
Sbjct: 700 EAQFGDFANGAQVVIDQFITSGEHKWQRLCGLTMLLPHGYEGQGPEHSSARLERFMQLCA 759
Query: 681 EDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKS 502
E N V TTPA +YH++RRQ P R+P VV SPK
Sbjct: 760 EH----------------------NIQVCIPTTPAQVYHMIRRQAIRPMRRPLVVMSPKW 797
Query: 501 LLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGK 322
+LRH +A S +E+ GS F+ VI G P + KRV+ C+GKVYY + AR+ +
Sbjct: 798 ILRHKLATSTLEELAEGS-FKTVI---GDDVVKPEEAKRVILCSGKVYYHLFEAREE-RE 852
Query: 321 ENDVALVRVEQLSPFPYDLVQQECRKYQG-AEILWAQEEHKNMGAWSFVQPRINSLLS-- 151
E DVAL+R+EQL PFP + ++ E KY G +++W QEE +N GAW Q R+ ++
Sbjct: 853 EKDVALIRIEQLYPFPEEALRVELAKYPGLVDVVWCQEEPQNQGAWYSSQHRMRRVVERV 912
Query: 150 IDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMS 49
+ +Y GR SS+PA G TH++EQ + ++
Sbjct: 913 NEDAELRYVGRASSSAPAAGYMSTHLEEQNKFIN 946
>gi|46141556|ref|ZP_00146844.2| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Psychrobacter sp. 273-4]
Length = 961
Score = 655 bits (1690), Expect = 0.0
Identities = 396/996 (39%), Positives = 562/996 (55%), Gaps = 23/996 (2%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L ++ YI+ +YE +L+DP+SV T W YF + A +
Sbjct: 16 LAADNANYIDILYEQYLEDPNSVGTDWQTYFEQYKSPNDEPHNAIKDQFLLLARNQTANK 75
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINS-ADLDD 2581
+ T SSA R + + Q + +Q LI +Y+ RGH A LDPL + A+++D
Sbjct: 76 VSTD-TNSSARGHRNNVGDNKQ-----MGVQQLISAYRRRGHRRAQLDPLSLYPRAEVED 129
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
L L+++ L E DLD F P K +LREI++ ++ +YC GVEYMH+
Sbjct: 130 -----LTLAYHNLSEADLDTVF--PTNDLNIGKNEASLREIIEIMERVYCRYIGVEYMHV 182
Query: 2400 NNLEQQDWIRRRFEAPRVTELSHDQKKVL--FKRLIRSTKFEEFLAKKWPSEKRFGLEGC 2227
++ W+ + E + +S D +K L +RL + E++LA+K+ KRFGLEG
Sbjct: 183 TTSTEKRWMEKYLET-NLGHISFDTEKRLSILERLTAAEGLEKYLARKYTGVKRFGLEGG 241
Query: 2226 EVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGS 2047
E IPA+ ++I + G VIGM HRGRLN+L N+ + A + +F ++GS
Sbjct: 242 ESFIPAINEIIQRAGGYGTKEMVIGMAHRGRLNLLVNILGKNPADLFDEFDGKVQPEKGS 301
Query: 2046 GDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTM 1867
GDVKYH G + + ++ +A NPSHLE V PV+ G VRA D+
Sbjct: 302 GDVKYHNGFSSNVMTPGGEAHLALAF--NPSHLEIVAPVLQGSVRARQVRRNDQSLHENK 359
Query: 1866 A------ILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSS-RS 1708
A I++HGDAAFAGQGVV ETF + +YTT G +HIV+NNQ+GFTT + RS
Sbjct: 360 AGNSVLPIVVHGDAAFAGQGVVQETFQMSQTRAYTTGGTLHIVINNQVGFTTSRQEDLRS 419
Query: 1707 SPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELD 1528
+ YCTDV ++V PI HVN DDPE+V+ +A D+R F KD+I+DL CYRR+GHNE D
Sbjct: 420 TEYCTDVAKMVHAPILHVNGDDPESVVFAAQLALDYRYEFDKDIIIDLFCYRRNGHNEAD 479
Query: 1527 EPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAY-ENAQKV 1351
EP TQPLMY IK+ T Y + ++ EG+ + KE+ T+ LED Y E+ +
Sbjct: 480 EPSATQPLMYAVIKKLPTTRTIYAQNLIAEGLLS----KEDETR----LEDEYRESLDRG 531
Query: 1350 TYVRNRDWLDSPWDDFFKKRDP------LKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRG 1189
YV N ++ P + F P + T + +Q PEG+ L R
Sbjct: 532 EYVAN-SLVNEPNEQLFVDWKPYLGHDLVDDWDTSVDIEVLKGYGRRMAQMPEGYKLQRQ 590
Query: 1188 LERTLKGRQQMLK-DNSLDWACGEALAFGSLLK-EGIHVRLSGQDVQRGTFSHRHHVLHD 1015
+++ ++ R M + L+W E LA+ SL+ + + VR++G+DV RGTFSHRH L++
Sbjct: 591 VQKVVEQRLAMQTGEEPLNWGAAETLAYASLVNNDKVLVRITGEDVGRGTFSHRHSELYN 650
Query: 1014 QKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSN 835
+ D +Y PL +SE Q ++ NS LSE AVL FE GY+ PN+LV+WEAQFGDF N
Sbjct: 651 IE-DGSMYVPLAHMSEDQARFSTYNSLLSEEAVLAFEYGYATTVPNALVVWEAQFGDFVN 709
Query: 834 TAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEK 655
AQ +IDQFI+SG++KW R GL MLLPHG+EG GPEHSSAR ERFLQ+C ED
Sbjct: 710 GAQVVIDQFIASGETKWQRVCGLTMLLPHGFEGQGPEHSSARLERFLQLCAED------- 762
Query: 654 IAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARS 475
N V TTPA IYH LRRQ P RKP +V SPKSLLRH +A S
Sbjct: 763 ---------------NMQVITPTTPAQIYHALRRQAVRPIRKPLIVMSPKSLLRHKLATS 807
Query: 474 PVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRV 295
+E+ +G F+ V+PE QNP +V R+V C GKVYY+++ R+ +G ++ VA+VR+
Sbjct: 808 QLEELANG-KFETVLPE--MDQQNPDNVTRMVLCGGKVYYELLEQRRALGLDH-VAIVRI 863
Query: 294 EQLSPFPYDLVQQECRKYQG-AEILWAQEEHKNMGAWSFVQPRINSLL---SIDGRATKY 127
EQL P P + E KY EI+W QEE N GAW ++ P + ++ + +
Sbjct: 864 EQLYPLPEKRLIAEIEKYSNLKEIVWTQEEPLNQGAWYYLAPHMFRIVVPHPTRAKVMEP 923
Query: 126 AGRLPSSSPATGNKFTHMQEQKEMMSKVFGVPKSKL 19
R S++PATG+ H+++Q+++++ G+ +L
Sbjct: 924 VARPASAAPATGSAKLHVKQQQDLIAGGLGISVDEL 959
>gi|34496526|ref|NP_900741.1| 2-oxoglutarate dehydrogenase E1
component [Chromobacterium violaceum ATCC 12472]
gi|34330299|gb|AAQ58746.2| 2-oxoglutarate dehydrogenase E1 component
[Chromobacterium violaceum ATCC 12472]
Length = 942
Score = 654 bits (1688), Expect = 0.0
Identities = 384/986 (38%), Positives = 546/986 (54%), Gaps = 15/986 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L G ++ +IE++YE +L D +SV W YF + L +
Sbjct: 10 YLFGGNAPFIEELYEQYLVDANSVPQEWRDYFDKLAQAPGAAERDVPH--------LPIQ 61
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDD 2581
+ Q+ R +++ + + LI +Y+ G A+LDPL +D
Sbjct: 62 ESFIQLAKKPVIGQRSAAATDWEAMRKQVGVLKLISAYRVLGARQANLDPL----KRMDQ 117
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
I EL+ + +GL + D+ +F + ++ + L L +IL RLK YC + GVEYMH+
Sbjct: 118 AIVRELDPATHGLTDADMAVQFNVGS---LAGPQKLPLSDILSRLKQTYCGNIGVEYMHI 174
Query: 2400 NNLEQQDWIRRRFEAPRVT-ELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCE 2224
+++ W+++RFE T D+KK + K++ + E +L K+ +KRF LEG E
Sbjct: 175 TQSDEKHWVQKRFEGDLSTPRYDADKKKRILKQITAAETLERYLHTKYVGQKRFSLEGGE 234
Query: 2223 VLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSG 2044
I A+ +I +++ GV +IGM HRGRLNVL N + + ++F SG
Sbjct: 235 SAIAALDHLIQNATEQGVQELIIGMAHRGRLNVLVNTLGKLPRDLFAEFEGKAAQQMASG 294
Query: 2043 DVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMA 1864
DVKYH+G + +V +A NPSHLE V+PVV G VRA D + +
Sbjct: 295 DVKYHMGFSSDIPTANGPMHVSLAF--NPSHLEIVNPVVEGSVRARQERRKDTERKTAVP 352
Query: 1863 ILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDV 1687
+L+HGD+AF G GV TFNL Y T G IHIV+NNQ+GFTT D R RS+ YCTDV
Sbjct: 353 VLIHGDSAFGGLGVNQGTFNLSQTRGYGTGGTIHIVINNQVGFTTSDTRDIRSTMYCTDV 412
Query: 1686 GRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQP 1507
+++ PI HVN DDPEAV +V A D+R TFKKDV++DLVCYR+ GHNE D+P TQP
Sbjct: 413 AKMIEAPILHVNGDDPEAVCYVMQAALDYRMTFKKDVVIDLVCYRKLGHNEGDDPFLTQP 472
Query: 1506 LMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVT---YVRN 1336
+MY++I + + Y E+++ EGV + ++ Y L D E+ ++ T Y R
Sbjct: 473 MMYKKIAKHQGVRAMYAERLVQEGVLKAEEADAQIQAYRDAL-DKGEHVEQTTLSNYKRE 531
Query: 1335 R-----DWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLK 1171
+L + W T KF+ PEGF LH +++ L
Sbjct: 532 HALDFSQYLGTHW---------AHPTDTSLPQADIQRLTDKFTTLPEGFKLHPTVQKVLA 582
Query: 1170 GRQQMLK-DNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQ---KVD 1003
R+ M + ++DW E LA+ SL+ G VR+SG+D RGTFSHRH VLHDQ + D
Sbjct: 583 ARKAMAAGEQNVDWGMAETLAYASLVTNGFGVRISGEDSGRGTFSHRHAVLHDQNRERWD 642
Query: 1002 QKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQC 823
Q Y PL ++S+ Q ++ V +S L+E AVL +E GY+ P+ LVIWEAQFGDF+N AQ
Sbjct: 643 QGTYVPLRNMSDNQADFLVIDSILNEEAVLAYEYGYACSAPDQLVIWEAQFGDFANGAQV 702
Query: 822 IIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFE 643
IDQFISSG++KW R GL +LPHGY+G GPEHSSAR ER+LQ+C E
Sbjct: 703 AIDQFISSGETKWGRLCGLTSILPHGYDGQGPEHSSARVERWLQLCAEH----------- 751
Query: 642 GTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVED 463
N + + ++HLLRRQV P+RKP V+F K LLR + SP+ED
Sbjct: 752 -----------NMQIVMPSEAGQMFHLLRRQVLRPYRKPLVIFLSKRLLRFKDSMSPIED 800
Query: 462 FQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLS 283
SG F+ VI + A ++P VKRV+ C G+VYYD+ AARK G E+D+A+VR+EQL
Sbjct: 801 LTSG-GFRPVIGD--AVVKDPKKVKRVLLCAGQVYYDLAAARKERGLEDDIAIVRIEQLY 857
Query: 282 PFPYDLVQQECRKY-QGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSS 106
PFP + V E ++ Q E++W QEE +N GAW ++ R+ LLS + +AGR S+
Sbjct: 858 PFPTEQVAAELARFTQAKEVMWVQEEPRNQGAWYQIRHRLEGLLSAK-QQLSFAGRPSSA 916
Query: 105 SPATGNKFTHMQEQKEMMSKVFGVPK 28
SPA G H+ + K + + V +
Sbjct: 917 SPAVGYMSKHVAQLKAFVEEAMSVAR 942
>gi|30250299|ref|NP_842369.1| Transketolase:Dehydrogenase, E1
component [Nitrosomonas europaea ATCC 19718]
gi|30181094|emb|CAD86286.1| Transketolase:Dehydrogenase, E1 component
[Nitrosomonas europaea ATCC 19718]
Length = 952
Score = 651 bits (1680), Expect = 0.0
Identities = 390/988 (39%), Positives = 556/988 (55%), Gaps = 22/988 (2%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G+++ +IE +YE +L+DP +V W YF +++ V
Sbjct: 11 LFGNNAAFIEMLYERYLEDPFAVSDQWRQYFDSLQPTETISVRDIPHTPV-------VES 63
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISD-------HLKIQLLIRSYQTRGHNIADLDPLGIN 2599
T P + + +++ SD + + LI +Y+ G A+LDPL +
Sbjct: 64 LVRSATLHKPPLSGTPSKQAIEQPSDTETQERKQVAVLQLINAYRFLGVRRANLDPLDLQ 123
Query: 2598 SADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTG 2419
D + EL+ F+GL + D+D+ F T + + TL+EIL RL+ YC S G
Sbjct: 124 QKQ--DIL--ELDPGFHGLTDTDMDKVF---NTGSLVGPEHATLQEILHRLQQTYCGSIG 176
Query: 2418 VEYMHLNNLEQQDWIRRRFEAPRVTE-LSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRF 2242
EYM++ + +Q+ WI+ R E+ + + K+ + +RL + E++L ++ +KRF
Sbjct: 177 AEYMYIADTKQKRWIQNRLESINAQPGFTPEYKRHILERLTAAEGLEKYLHNRYVGQKRF 236
Query: 2241 GLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEP 2062
EG E LIP + +++ + GV V+GM HRGRLNVL N + + + +F P
Sbjct: 237 SGEGNESLIPMLDKLLQHAGISGVQEIVMGMAHRGRLNVLVNTLGKMPSELFQEFEGKHP 296
Query: 2061 ADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEK 1882
SGDVKYH G + S +++A+ NPSHLE V+PVV G VRA GD+
Sbjct: 297 QALTSGDVKYHQGFSSAVMT--SGGIMRLALAFNPSHLEIVNPVVEGSVRARQHRFGDKN 354
Query: 1881 CDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSS 1705
D + +L+HGDAAFAGQGVV+ET NL Y T G IHI++NNQIGFTT DPR SRS+
Sbjct: 355 GDHVIPVLIHGDAAFAGQGVVMETLNLSQTRGYGTGGTIHIIINNQIGFTTSDPRDSRST 414
Query: 1704 PYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDE 1525
YCTDV +++ P+FHVN DDPEAV+ +A D+R F +DV++DLVC+R+ GHNE DE
Sbjct: 415 LYCTDVVKMIDAPVFHVNGDDPEAVVLATEIAFDFRMQFHRDVVIDLVCFRKQGHNEQDE 474
Query: 1524 PMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTY 1345
PM TQP MY+ I Q + Y + ++ +GV + V+ + Y +++ + Y
Sbjct: 475 PMVTQPSMYRVIHQHPGTRKLYADGLIRQGVVDNADVEHMVQSYQDAMDEGRNPNTTICY 534
Query: 1344 VRNR----DWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERT 1177
+W+ P+ K P+ +TG + + P F LH +E+
Sbjct: 535 DYKSPNVANWV--PFQASEKWNQPV---TTGVPVEDLKYLSERLTTIPATFKLHPRVEKI 589
Query: 1176 LKGRQQMLKDN-SLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQ 1000
++ R++M + + LDW E LA+ +LLKEG VR+SGQD RGTF HRH VLHDQ +Q
Sbjct: 590 IQDRRKMGEGSLPLDWGMAENLAYAALLKEGYPVRISGQDCGRGTFFHRHAVLHDQNREQ 649
Query: 999 K-----IYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSN 835
Y PL ++ Q ++ V +S LSE AVLGFE GY+ PN LVIWEAQFGDF+N
Sbjct: 650 DQWEDGTYIPLRHITPRQPDFVVIDSILSEEAVLGFEYGYATAQPNELVIWEAQFGDFAN 709
Query: 834 TAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEK 655
AQ +IDQFI+SG++KW R GLV+LLPHGYEG GPEHSSAR ER+LQ+C E
Sbjct: 710 GAQVVIDQFIASGEAKWGRLCGLVLLLPHGYEGQGPEHSSARLERYLQLCAE-------- 761
Query: 654 IAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARS 475
N V +TPA I+HLLRRQ+ P RKP +V SPKS+LRH A S
Sbjct: 762 --------------YNIQVCVPSTPAQIFHLLRRQIIRPIRKPLIVMSPKSMLRHKEAVS 807
Query: 474 PVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARK--HVGKENDVALV 301
+E+ +G FQ ++PET A VKR++ C+GK+YY++ A R+ H+ ++A++
Sbjct: 808 SLEELANG-RFQPILPETEA--FEIEKVKRLIVCSGKIYYELTAYRREHHI---TNMAII 861
Query: 300 RVEQLSPFPYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYA 124
R+EQL PFP++ Q E +Y A EILW QEE N GAW +Q + + D + YA
Sbjct: 862 RLEQLYPFPHEDFQAEINRYDHATEILWCQEEPGNQGAWHRIQHYLLRHMRPD-QILGYA 920
Query: 123 GRLPSSSPATGNKFTHMQEQKEMMSKVF 40
R S+SP+ G QKE++ F
Sbjct: 921 LRPSSASPSVGYLAMDRFRQKELIEAAF 948
>gi|15604055|ref|NP_220570.1| 2-OXOGLUTARATE DEHYDROGENASE E1
COMPONENT (sucA) [Rickettsia prowazekii str. Madrid E]
gi|6647694|sp|Q9ZDY3|ODO1_RICPR 2-oxoglutarate dehydrogenase E1
component (Alpha-ketoglutarate dehydrogenase)
gi|7431589|pir||H71728 2-oxoglutarate dehydrogenase e1 component
(sucA) RP180 - Rickettsia prowazekii
gi|3860746|emb|CAA14647.1| 2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT
(sucA) [Rickettsia prowazekii]
Length = 936
Score = 651 bits (1679), Expect = 0.0
Identities = 372/983 (37%), Positives = 562/983 (56%), Gaps = 9/983 (0%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L +++++E++Y +L +P+SV +W +F +++
Sbjct: 10 YLFSGNAVFVEELYRQYLANPNSVDQTWQEFFADIKDNNVVLNKST-------------- 55
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDD 2581
A ++T+ L+ N S +++++ LK + +I +Y+ H +A+LDPLG+ +
Sbjct: 56 --AKVISTNVTNKELLNNNLSSETLNN-LKAKEMISAYRRNAHYLANLDPLGLEIRKTKN 112
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
+ +L + +GL L + FI + L E++ +L +Y +S GVE+ +
Sbjct: 113 DL--KLNIEAFGLDSSQLGENINIMDE-FIGTW-NCKLSELVTKLDKVYTSSIGVEFDQI 168
Query: 2400 NNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEV 2221
N+E+++W+ + E + ++KK + L+ FE+FL K+P KRF +EG +
Sbjct: 169 ENVEEKNWLYTKLETD--ITFTSEEKKSILNDLVEVECFEQFLHIKFPGAKRFSIEGGDA 226
Query: 2220 LIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEG--- 2050
I AM + ID S GV+ VIGM HRGRLN L V +P +++ F +G
Sbjct: 227 SIVAMNKAIDLSMHQGVEEIVIGMAHRGRLNTLTKVVGKPYKEVIASFINGNIFPDGLNV 286
Query: 2049 SGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRT 1870
SGDVKYHLG +R+ R +QK + +++ NPSHLEA++ +V GKVRA+ D K +
Sbjct: 287 SGDVKYHLGYSADRV-RANQK-IHLSLADNPSHLEAINSIVAGKVRAKQDIFVDTKRSKI 344
Query: 1869 MAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTD 1690
AIL+HGDAAF GQGVV E+ ++ L +Y G +H V+NNQ+GFT + +R+S Y T+
Sbjct: 345 KAILVHGDAAFCGQGVVAESLSMSPLTAYNVGGILHFVINNQLGFTANAADTRASRYSTE 404
Query: 1689 VGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQ 1510
+++ PI HVN DD EAV+ ++A ++R+ F KDV+V+++CYR++GHNE DEPM+TQ
Sbjct: 405 FAKIISAPILHVNGDDIEAVLKATDIAVEYRQKFSKDVVVEIICYRKYGHNEGDEPMYTQ 464
Query: 1509 PLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRD 1330
MY IK T Y +++ G+ + Y + K+ L+ YE A+ +Y +
Sbjct: 465 SKMYNIIKSKPTPGSIYANELVKNGIIDNNYYAKLKEKFKIRLDQEYEQAK--SYKQETH 522
Query: 1329 WLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQML- 1153
+ + W + R K TG K + P+ F ++ L R + R+ L
Sbjct: 523 FFEGYWKGISRIRG--KDAITGVNKKILQDLGTKLCEIPKDFAINPKLIRLFEVRKTTLT 580
Query: 1152 KDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDL 973
D +DWA E LAF LL GI++RL+GQD RGTFSHRH +LH+Q +D Y PLN+L
Sbjct: 581 TDQPIDWATAEQLAFAHLLCSGINIRLTGQDSARGTFSHRHSILHNQ-IDDTTYIPLNNL 639
Query: 972 SEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQ 793
S+ Q +Y V NS+LSEYA LGFE GYS+ +P +LV+WEAQFGDF+N AQ I DQFISS
Sbjct: 640 SKTQAKYEVANSNLSEYAALGFEYGYSLANPKNLVLWEAQFGDFANGAQIIFDQFISSSA 699
Query: 792 SKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHD 613
+KW+R SGLV+LLPH +EG GPEHSSAR ERFLQ+ E+
Sbjct: 700 TKWLRMSGLVVLLPHAFEGQGPEHSSARLERFLQLAAEE--------------------- 738
Query: 612 TNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRV 433
N + TTPA+I+HLLRRQ+ RKP +V SPKSLLRH A S +++ + F +
Sbjct: 739 -NMYITYPTTPASIFHLLRRQILESTRKPLIVMSPKSLLRHKYAVSKLDELGENTTFIPI 797
Query: 432 IPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQE 253
+ E N +V +V+ C+GKVYYD+ A R + +++ ++R+EQL PF LV
Sbjct: 798 LDEVTKIDTN--NVTKVILCSGKVYYDLFAMRTN---NSNIVIIRLEQLYPFEKKLVASL 852
Query: 252 CRKYQGAE-ILWAQEEHKNMGAWSFVQPRINSLL--SIDGRATKYAGRLPSSSPATGNKF 82
+KY A+ +W QEE KNMGAW ++ +N L + KY GR S+SPA G+
Sbjct: 853 LKKYNKAQAFIWCQEEPKNMGAWHYIATHLNDALKEAEINNEFKYVGREESASPAVGSLQ 912
Query: 81 THMQEQKEMMSKVFG--VPKSKL 19
H ++Q++++ + G + K KL
Sbjct: 913 VHNKQQEKLLMEALGDDIIKEKL 935
>gi|29829514|ref|NP_824148.1| putative 2-oxoglutarate dehydrogenase
[Streptomyces avermitilis MA-4680]
gi|29606622|dbj|BAC70683.1| putative 2-oxoglutarate dehydrogenase
[Streptomyces avermitilis MA-4680]
Length = 1276
Score = 650 bits (1677), Expect = 0.0
Identities = 376/889 (42%), Positives = 521/889 (58%), Gaps = 15/889 (1%)
Frame = -1
Query: 2661 LIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEK 2482
LI SY+ RGH +AD DPL P+L+++ +GL DL+REF + + K
Sbjct: 429 LIHSYRVRGHVMADTDPLEYRQRK-----HPDLDITEHGLTLWDLEREFAVGG---FAGK 480
Query: 2481 KSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRL 2302
+ LR+IL L+D YC +TG+E+MH+ + +Q+ WI+ R E +Q ++L +RL
Sbjct: 481 SLMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRIERSHSKPEREEQLRIL-RRL 539
Query: 2301 IRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVL 2122
+ FE FL K+ +KRF LEG E +IP + VIDS++ +D VIGM HRGRLNVL
Sbjct: 540 NAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVL 599
Query: 2121 ANVCRQPLATILSQFS-TLEPAD-EGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHL 1948
AN+ + A I +F L+P GSGDVKYHLG ++ +K+++ ANPSHL
Sbjct: 600 ANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGASGTFTGLDGEQ-IKVSLAANPSHL 658
Query: 1947 EAVDPVVMGKVRAEAFYAGDEKCDRT-MAILLHGDAAFAGQGVVLETFNLDDLPSYTTHG 1771
E VDP++ G RA+ D T + + LHGDAAFAGQGVV ET N+ L Y T G
Sbjct: 659 ETVDPIIEGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGG 718
Query: 1770 AIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKT 1591
+HIV+NNQ+GFT P SSRSS Y TDV R++ PIFHVN DDPEAV+ V +A ++R+
Sbjct: 719 TVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQA 778
Query: 1590 FKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVK 1411
F KDV++DL+CYRR GHNE D P FTQPLMY I + ++ + Y E ++ G + +
Sbjct: 779 FNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAE 838
Query: 1410 EELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIG 1231
+ L + LE + ++ P +F P+ +P+
Sbjct: 839 QALQDFQGQLEKVFTEVREAISTPGEAPAPEPQPEF-----PVAVPTAVSQEVVKRIAES 893
Query: 1230 KFSQYPEGFNLHRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQR 1051
+ + P+ +H L L+ R M++D+++DW GE LA GSLL EG VRLSGQD +R
Sbjct: 894 QVN-IPDHVTVHPRLLPQLQRRAAMIEDDTIDWGMGETLAIGSLLLEGTPVRLSGQDSRR 952
Query: 1050 GTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSL 871
GTF RH VL D +V + + PL L++ Q V +S LSEYAV+GFE GYS+ P++L
Sbjct: 953 GTFGQRHAVLID-RVTGEDFTPLQYLADDQARLNVYDSLLSEYAVMGFEYGYSLARPDAL 1011
Query: 870 VIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQ 691
V+WEAQFGDF N AQ ++D++IS+ + KW + SG+ +LLPHGYEG GP+HSSAR ERFLQ
Sbjct: 1012 VMWEAQFGDFVNGAQTVVDEYISAAEQKWGQTSGVTLLLPHGYEGQGPDHSSARIERFLQ 1071
Query: 690 MCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFS 511
+C ++ N VA T P+N +HLLR QV P KP VVF+
Sbjct: 1072 LCAQN----------------------NMTVAQPTLPSNYFHLLRWQVHNPHHKPLVVFT 1109
Query: 510 PKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKH 331
PKS+LR A S E+F +G+ F+ VI G + + V++VVFC GK+YYD+ A RK
Sbjct: 1110 PKSMLRLKAAASKTEEFTTGA-FRPVI---GDDTVDAAAVRKVVFCAGKLYYDLEAERKK 1165
Query: 330 VGKEN----DVALVRVEQLSPFPYDLVQQECRKYQGAE-ILWAQEEHKNMGAWSFVQPRI 166
G + + A++R+E+L P P +Q E KY AE LWAQEE N GAW F+ +
Sbjct: 1166 RGATDAAAAETAIIRLERLYPLPGAELQAEIAKYPNAEKYLWAQEEPANQGAWPFIALNL 1225
Query: 165 NSLLSI-------DGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVF 40
L + G + R SSSPA G+ H EQ++++ +VF
Sbjct: 1226 IDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQEQLVREVF 1274
Score = 35.8 bits (81), Expect = 6.5
Identities = 17/70 (24%), Positives = 31/70 (44%)
Frame = -1
Query: 2931 GSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAA 2752
G + ++++Y+ +LQDP+SV +W +F + + A +PAA
Sbjct: 26 GPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKPGAAAASAPAGTAAAGAAETTTPAPAA 85
Query: 2751 AQVTTSSAPA 2722
+APA
Sbjct: 86 PTAAAPAAPA 95
>gi|23467323|ref|ZP_00122906.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Haemophilus somnus 129PT]
Length = 934
Score = 649 bits (1673), Expect = 0.0
Identities = 381/977 (38%), Positives = 547/977 (54%), Gaps = 13/977 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G++ Y+E +YE +L +P +V SW F ++ A S
Sbjct: 19 LGGANQSYVEDLYEDYLDNPQAVDESWQQVFNSLPKQNALEQPHSKVRDYFKRLARDTSQ 78
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 2578
V +D N S + ++ + I ++ RGH ADLDPL +
Sbjct: 79 NGVGV---------IDPNVSARLVN----VLKWINGHRNRGHLHADLDPLKM----WQRM 121
Query: 2577 IPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLN 2398
P L+ FYG + DLD F + ++ K+ ++LR++ LK YC++ G+E+MH+N
Sbjct: 122 EAPTLDYKFYGFSDNDLDEVFDIGG--YVYNKEQISLRDLADSLKKTYCSTIGLEFMHVN 179
Query: 2397 NLEQQDWIRRRFEAPRVTELSHDQKKVLF-KRLIRSTKFEEFLAKKWPSEKRFGLEGCEV 2221
+L+ + W++R+ E L ++++ F + LI + E +L K+P KRF LEG +
Sbjct: 180 DLDARTWLQRKVERLLDKPLFTREEQLKFLEELIAADGLERYLGAKFPGAKRFSLEGSDA 239
Query: 2220 LIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGD 2041
I MK++I SS GV V+GM HRGRLN+L NV + + + +F+ + + G+GD
Sbjct: 240 FILLMKEMIRHSSRNGVKEIVMGMAHRGRLNLLVNVLGKKPSELFDEFAG-KHSGSGTGD 298
Query: 2040 VKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAI 1861
VKYH G + + V +A+ NPSHLE V+PVV+G VRA D + + + I
Sbjct: 299 VKYHQGFSSDFMTDDGI--VHLALAFNPSHLEIVNPVVLGSVRARQNRIQDVERSQVLPI 356
Query: 1860 LLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDP-RSSRSSPYCTDVG 1684
+HGD+A AGQG+V ET N+ ++ YT G I +V+NNQIGFTT + +RS+ YCTD+
Sbjct: 357 TVHGDSAVAGQGIVQETLNMSEVRGYTVGGTIRVVINNQIGFTTSNLQDTRSTEYCTDIA 416
Query: 1683 RVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPL 1504
+++ P+ HVN DDPEAV + +A ++R FK+D+ +DLV YRRHGHNE DEP TQPL
Sbjct: 417 KMIEAPVIHVNGDDPEAVAYAARMAVEFRAKFKRDIFIDLVSYRRHGHNEADEPAVTQPL 476
Query: 1503 MYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTY------V 1342
MY+RI++ T + Y +++ EG+ +E Y E KY DA +N V +
Sbjct: 477 MYERIRKHPTPPKVYTNRLVTEGIIDEAYAIELANKY----RDALDNGGCVVPEWREADI 532
Query: 1341 RNRDW---LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLK 1171
+DW L W ++ D + K YP +LH +++
Sbjct: 533 ETKDWTKYLTQEWTEYDGSFDSERFVGLAK----------KVCDYPSSHSLHPRVKKLYD 582
Query: 1170 GRQQMLKDNSL-DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKI 994
R M + + L DW E +A+ +LL EG +VRLSG+D RGTF HRH VLH+QK D +
Sbjct: 583 DRLSMAQGDKLFDWGMAETMAYATLLDEGYNVRLSGEDAGRGTFFHRHSVLHNQK-DATL 641
Query: 993 YNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIID 814
Y PL L QG + V +S LSE AVL +E GY+ P +L IWEAQFGDF+N AQ +ID
Sbjct: 642 YIPLTQLHAQQGRFEVWDSVLSEEAVLAYEYGYATAAPRTLTIWEAQFGDFANVAQVVID 701
Query: 813 QFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTF 634
QFISSG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C
Sbjct: 702 QFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLC----------------- 744
Query: 633 EAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQS 454
AQQ N V +TPA IYHLLRRQ+ R+P VV +PKSLLR P+ S +E+
Sbjct: 745 -AQQ----NMQVCVPSTPAQIYHLLRRQMLRKVRRPLVVITPKSLLRRPLVVSTMEELIH 799
Query: 453 GSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFP 274
G +Q VI E A +P V+RVV C+GKVYYD++ R+ + DVA++R+EQL P+P
Sbjct: 800 G-KYQNVIAEIDA--IDPQKVRRVVMCSGKVYYDLLEQRRE-NNQMDVAIIRIEQLYPYP 855
Query: 273 YDLVQQECRKYQG-AEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPA 97
++ +++ Y + +W QEE N GAW Q + L G+ +Y GR S+SPA
Sbjct: 856 HEEMKEALAPYSHVTDYVWCQEEPLNQGAWYCCQHNFWTSLPPHGK-LRYVGRPASASPA 914
Query: 96 TGNKFTHMQEQKEMMSK 46
G H ++Q+ ++++
Sbjct: 915 VGYLSLHNEQQRALVTE 931
>gi|32030042|ref|ZP_00132962.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Haemophilus somnus 2336]
Length = 931
Score = 649 bits (1673), Expect = 0.0
Identities = 381/977 (38%), Positives = 547/977 (54%), Gaps = 13/977 (1%)
Frame = -1
Query: 2937 LNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSP 2758
L G++ Y+E +YE +L +P +V SW F ++ A S
Sbjct: 16 LGGANQSYVEDLYEDYLDNPQAVDESWQQVFNSLPKQNALEQPHSKVRDYFKRLARDTSQ 75
Query: 2757 AAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDT 2578
V +D N S + ++ + I ++ RGH ADLDPL +
Sbjct: 76 NGVGV---------IDPNVSARLVN----VLKWINGHRNRGHLHADLDPLKM----WQRM 118
Query: 2577 IPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLN 2398
P L+ FYG + DLD F + ++ K+ ++LR++ LK YC++ G+E+MH+N
Sbjct: 119 EAPTLDYKFYGFSDNDLDEVFDIGG--YVYNKEQISLRDLADSLKKTYCSTIGLEFMHVN 176
Query: 2397 NLEQQDWIRRRFEAPRVTELSHDQKKVLF-KRLIRSTKFEEFLAKKWPSEKRFGLEGCEV 2221
+L+ + W++R+ E L ++++ F + LI + E +L K+P KRF LEG +
Sbjct: 177 DLDARTWLQRKVERLLDKPLFTREEQLKFLEELIAADGLERYLGAKFPGAKRFSLEGSDA 236
Query: 2220 LIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGD 2041
I MK++I SS GV V+GM HRGRLN+L NV + + + +F+ + + G+GD
Sbjct: 237 FILLMKEMIRHSSRNGVKEIVMGMAHRGRLNLLVNVLGKKPSELFDEFAG-KHSGSGTGD 295
Query: 2040 VKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAI 1861
VKYH G + + V +A+ NPSHLE V+PVV+G VRA D + + + I
Sbjct: 296 VKYHQGFSSDFMTDDGI--VHLALAFNPSHLEIVNPVVLGSVRARQNRIQDVERSQVLPI 353
Query: 1860 LLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDP-RSSRSSPYCTDVG 1684
+HGD+A AGQG+V ET N+ ++ YT G I +V+NNQIGFTT + +RS+ YCTD+
Sbjct: 354 TVHGDSAVAGQGIVQETLNMSEVRGYTVGGTIRVVINNQIGFTTSNLQDTRSTEYCTDIA 413
Query: 1683 RVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPL 1504
+++ P+ HVN DDPEAV + +A ++R FK+D+ +DLV YRRHGHNE DEP TQPL
Sbjct: 414 KMIEAPVIHVNGDDPEAVAYAARMAVEFRAKFKRDIFIDLVSYRRHGHNEADEPAVTQPL 473
Query: 1503 MYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTY------V 1342
MY+RI++ T + Y +++ EG+ +E Y E KY DA +N V +
Sbjct: 474 MYERIRKHPTPPKVYTNRLVTEGIIDEAYAIELANKY----RDALDNGGCVVPEWREADI 529
Query: 1341 RNRDW---LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLK 1171
+DW L W ++ D + K YP +LH +++
Sbjct: 530 ETKDWTKYLTQEWTEYDGSFDSERFVGLAK----------KVCDYPSSHSLHPRVKKLYD 579
Query: 1170 GRQQMLKDNSL-DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKI 994
R M + + L DW E +A+ +LL EG +VRLSG+D RGTF HRH VLH+QK D +
Sbjct: 580 DRLSMAQGDKLFDWGMAETMAYATLLDEGYNVRLSGEDAGRGTFFHRHSVLHNQK-DATL 638
Query: 993 YNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIID 814
Y PL L QG + V +S LSE AVL +E GY+ P +L IWEAQFGDF+N AQ +ID
Sbjct: 639 YIPLTQLHAQQGRFEVWDSVLSEEAVLAYEYGYATAAPRTLTIWEAQFGDFANVAQVVID 698
Query: 813 QFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTF 634
QFISSG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C
Sbjct: 699 QFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLC----------------- 741
Query: 633 EAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQS 454
AQQ N V +TPA IYHLLRRQ+ R+P VV +PKSLLR P+ S +E+
Sbjct: 742 -AQQ----NMQVCVPSTPAQIYHLLRRQMLRKVRRPLVVITPKSLLRRPLVVSTMEELIH 796
Query: 453 GSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFP 274
G +Q VI E A +P V+RVV C+GKVYYD++ R+ + DVA++R+EQL P+P
Sbjct: 797 G-KYQNVIAEIDA--IDPQKVRRVVMCSGKVYYDLLEQRRE-NNQMDVAIIRIEQLYPYP 852
Query: 273 YDLVQQECRKYQG-AEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPA 97
++ +++ Y + +W QEE N GAW Q + L G+ +Y GR S+SPA
Sbjct: 853 HEEMKEALAPYSHVTDYVWCQEEPLNQGAWYCCQHNFWTSLPPHGK-LRYVGRPASASPA 911
Query: 96 TGNKFTHMQEQKEMMSK 46
G H ++Q+ ++++
Sbjct: 912 VGYLSLHNEQQRALVTE 928
>gi|29654692|ref|NP_820384.1| 2-oxoglutarate dehydrogenase, E1
component [Coxiella burnetii RSA 493]
gi|30581055|sp|P51056|ODO1_COXBU 2-oxoglutarate dehydrogenase E1
component (Alpha-ketoglutarate dehydrogenase)
gi|541238|pir||S42874 oxoglutarate dehydrogenase (lipoamide) (EC
1.2.4.2) - Coxiella burnetii
gi|457725|emb|CAA54874.1| putative 2-oxoglutarate dehydrogenase
[Coxiella burnetii]
gi|29541960|gb|AAO90898.1| 2-oxoglutarate dehydrogenase, E1 component
[Coxiella burnetii RSA 493]
Length = 934
Score = 648 bits (1671), Expect = 0.0
Identities = 374/983 (38%), Positives = 552/983 (56%), Gaps = 14/983 (1%)
Frame = -1
Query: 2940 FLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVS 2761
+L +++ YIE +YE +L+DP SV+ W +YFR + +
Sbjct: 14 YLADNNAGYIETLYENFLKDPHSVNEEWRSYFRTLTNGASTPDISHATIREEFR------ 67
Query: 2760 PAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDD 2581
A+ S +P ++ ++ + LLI Y+ GH A ++PLG N
Sbjct: 68 -ELARKPRSISPT-------AITPAAEQAAVDLLIEGYRRFGHLNAKINPLGDNRP---- 115
Query: 2580 TIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHL 2401
+ LEL Y L E D ++ F T + K TL+EI RL++IYC S GV+Y +
Sbjct: 116 -VDSRLELGHYNLTESDFNKTFA---TYGLLNKPKATLKEIYTRLREIYCGSIGVQYSTI 171
Query: 2400 NNLEQQDWIRRRFEA--PRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGC 2227
++ +++W+R E P + E + K+ + ++L+ + E++L K+ + R+ LEG
Sbjct: 172 SDERERNWLRDYVEQRLPSI-EFDKETKRNILQQLVTAESLEKYLDTKYVGQVRYSLEGG 230
Query: 2226 EVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGS 2047
+ LIP + ++ + ++ VI M HRGR+NVL N+ Q A + +F + S
Sbjct: 231 DSLIPLLDELTKRARHQKIEEIVICMAHRGRVNVLLNIMGQSAAELFQEFEGKKDYGLMS 290
Query: 2046 GDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTM 1867
GDVKYH G R + + +++ NPSHLE + PV MG VRA K D M
Sbjct: 291 GDVKYHRGY--SRDVKTDAGPIHLSLAFNPSHLEFICPVAMGSVRARQERQNGHKRDYAM 348
Query: 1866 AILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTD 1690
+++HGDA+F+G+G+V+E ++ ++ G+IHI++NNQ+GFTT +P +RSS YC+D
Sbjct: 349 TVMIHGDASFSGEGIVMEALSMSQTRAHHVGGSIHIILNNQVGFTTSNPHDARSSMYCSD 408
Query: 1689 VGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQ 1510
+ +++ P+FHVN DDPEAV+ V +A D+R F KDV +DLVCYRRHGH E+D+PM TQ
Sbjct: 409 IAKMLDAPVFHVNGDDPEAVVAVTQLALDYRMAFHKDVFIDLVCYRRHGHQEVDDPMPTQ 468
Query: 1509 PLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKY------GSILEDAYENAQKVT 1348
P MY+ I++ T Y + ++ + + + V + + Y G L +
Sbjct: 469 PAMYKVIQEHPTTRTLYAKNLIEKKLCTAEEVDQWIDDYRDRLDRGRQLVETLPEGLSAH 528
Query: 1347 YVRN-RDWLDSPWDDFFKKRDPLK-LPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTL 1174
Y N +L W PLK L + G KFS P +LHR +E
Sbjct: 529 YAANWTPYLGQDWTTLVDTTLPLKKLKALGK----------KFSTLPNTLHLHRKVEAIY 578
Query: 1173 KGRQQMLKDNS-LDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQK 997
K R +M + + +DW E LA+ SLL+EG VRL GQD +RGTF HRH V+ DQ+ ++
Sbjct: 579 KARLEMAEGKTPMDWGFAEMLAYASLLEEGFSVRLVGQDSRRGTFFHRHAVVFDQETGKE 638
Query: 996 IYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCII 817
Y PL LS+ Q + +S L E LGFE GYS DPNSLVIWEAQFGDF+N AQ I+
Sbjct: 639 -YEPLKHLSDKQAAPHIYDSLLCEAGALGFEYGYSTADPNSLVIWEAQFGDFANVAQVIV 697
Query: 816 DQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGT 637
DQFISSG KW R SG+V+ LPHGYEG GPEHSSAR ER+LQ+C ++
Sbjct: 698 DQFISSGWQKWNRLSGIVLFLPHGYEGKGPEHSSARLERYLQLCAQN------------- 744
Query: 636 FEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQ 457
N V TTP+ I+HLLRRQV P+RKP VV +PKS+LR+ +A S +ED
Sbjct: 745 ---------NMQVCAPTTPSQIFHLLRRQVLRPYRKPLVVLTPKSVLRNKLAVSSLEDLA 795
Query: 456 SGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARK-HVGKENDVALVRVEQLSP 280
G + +IPE +P + RV+ C+GKVYYD++A R+ H GK N +A++R+EQL P
Sbjct: 796 RG-QLKLLIPE--IEKHDPKKITRVILCSGKVYYDLLAKRREHKGKLNHIAMIRIEQLYP 852
Query: 279 FPYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSS 103
FPYD ++ E KY A +++W QEE KN GAW + R+ + D + +Y GR ++
Sbjct: 853 FPYDELKAELEKYPNAKQVIWCQEEPKNQGAWFCTRHRLIKCMR-DDQTLEYVGRSAFAA 911
Query: 102 PATGNKFTHMQEQKEMMSKVFGV 34
PA G +++ Q++++++ +
Sbjct: 912 PAAGYSALYVKLQEQLVNQALEI 934
>gi|32034767|ref|ZP_00134892.1| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Actinobacillus pleuropneumoniae serovar 1 str.
4074]
Length = 936
Score = 642 bits (1656), Expect = 0.0
Identities = 382/992 (38%), Positives = 548/992 (54%), Gaps = 13/992 (1%)
Frame = -1
Query: 2988 VQHRNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXX 2809
+QH+N A PF GS+ Y+E++YE +L++P++V SW F +
Sbjct: 1 MQHKNFEDWLA--SSPF-GGSNQTYVEEIYEQYLENPANVDASWRVIFDTLP--KTQVVE 55
Query: 2808 XXXXXXXAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHN 2629
Y L VT +D AS + + ++ I +++ RG+
Sbjct: 56 QPHSQVRDYFRKLARENVPESVTV-------IDPEASAKQV----RLLQWINAHRFRGYL 104
Query: 2628 IADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQR 2449
A LDP IN ++ PEL+ +G E DL+ + ++ K+++ E+
Sbjct: 105 EAKLDP--INYYRWKISVVPELDYRHHGFTEADLNETVTI--GKYVYGKETMKFGELADA 160
Query: 2448 LKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTEL-SHDQKKVLFKRLIRSTKFEEFL 2272
LK Y + G+E+MH+ ++EQ++W++ + E+ L +H +K L L + E +L
Sbjct: 161 LKQTYLGTIGLEFMHVQDMEQRNWLQAKIESTLNKPLFTHTEKVNLLTELTAADGLERYL 220
Query: 2271 AKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLAT 2092
K+P KRF LEG + IP MK++I + G+ V+GM HRGRLN+L NV + A
Sbjct: 221 GAKFPGAKRFSLEGSDAFIPMMKEIIRHAGRQGMKDVVMGMAHRGRLNMLVNVLGKRPAE 280
Query: 2091 ILSQFSTLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVR 1912
+ +F+ D +GDVKYH G + + V + + NPSHLE V PVV+G VR
Sbjct: 281 LFDEFAGKHADDNRTGDVKYHQGFSSD--FDVDGERVHLTLAFNPSHLEIVSPVVIGSVR 338
Query: 1911 AEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFT 1732
A D + ++ +A+ +HGD+A AGQGVV ET N+ + Y G I IV+NNQIGFT
Sbjct: 339 ARQERIRDTEHNKVLAVTVHGDSAVAGQGVVQETLNMSNARGYKVGGTIRIVINNQIGFT 398
Query: 1731 T-DPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCY 1555
T +P +RS+ +CTD+ +++ PI HVN DDPEAV +A ++R FK+D+ +DL+ Y
Sbjct: 399 TSNPNDTRSTEFCTDIAKMIQAPIIHVNGDDPEAVAFAARMAVEYRTLFKRDIFIDLISY 458
Query: 1554 RRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILED 1375
RRHGHNE DEP+ TQP+MY IK+ T + Y ++++ EGV N+ E + Y D
Sbjct: 459 RRHGHNEADEPLATQPMMYSIIKKHPTPRKVYADRLVAEGVLNQDQATEIMNNY----RD 514
Query: 1374 AYENAQKVT------YVRNRDW---LDSPWDDFFKKRDPLKLPSTGXXXXXXXXXIGKFS 1222
A +N +V + DW L+ W ++ + P +
Sbjct: 515 ALDNGDRVVPEWREMDMAAVDWLQYLNYDWTAPYESKFP---------QDRFYTLAKRVC 565
Query: 1221 QYPEGFNLHRGLERTLKGRQQMLKDNS-LDWACGEALAFGSLLKEGIHVRLSGQDVQRGT 1045
+YPE H +E+ R++M + LDW E +A+ +LL EG HVRLSG+D RGT
Sbjct: 566 EYPESLRPHSRVEKIYSDRKEMYEGKKLLDWGMAETMAYATLLDEGTHVRLSGEDAGRGT 625
Query: 1044 FSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVI 865
F HRH V+H+Q D Y PL L QG + V +S LSE AVL FE GY+ DP +L I
Sbjct: 626 FFHRHAVVHNQN-DGTGYVPLAHLHANQGRFEVWDSVLSEEAVLAFEYGYATTDPKTLTI 684
Query: 864 WEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMC 685
WEAQFGDF+N AQ +IDQFISSG+ KW R GLVMLLPHGYEG GPEHSSAR ER+LQ+C
Sbjct: 685 WEAQFGDFANGAQIVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLC 744
Query: 684 NEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPK 505
AQQ N V +TPA YH+LRRQ R+P V +PK
Sbjct: 745 ------------------AQQ----NMQVCVPSTPAQAYHMLRRQAIRKMRRPLVAITPK 782
Query: 504 SLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVG 325
SLLRHP+A S +E+ G FQ VI E + + VKRVV C+GKVYYD++ R+
Sbjct: 783 SLLRHPLAVSSLEELTEG-EFQNVIGEIDS-NIAAKKVKRVVMCSGKVYYDLLEQRRQ-N 839
Query: 324 KENDVALVRVEQLSPFPYDLVQQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSI 148
++ D+A++R+EQL PFPY+ +++ Y + +W QEE +N GAW + + +
Sbjct: 840 EQTDIAIIRIEQLYPFPYEDMKKVLEPYAHVKDFVWCQEEPQNQGAWYCSKHNFEASIPE 899
Query: 147 DGRATKYAGRLPSSSPATGNKFTHMQEQKEMM 52
+ T YAGR S+SPA G H Q+QK+++
Sbjct: 900 KAKLT-YAGRPASASPAVGYTSLHAQQQKQLV 930
>gi|31792441|ref|NP_854934.1| PROBABLE 2-OXOGLUTARATE DEHYDROGENASE
SUCA (Alpha-ketoglutarate dehydrogenase) [Mycobacterium
bovis AF2122/97]
gi|31618030|emb|CAD94141.1| PROBABLE 2-OXOGLUTARATE DEHYDROGENASE
SUCA (Alpha-ketoglutarate dehydrogenase) [Mycobacterium
bovis AF2122/97]
Length = 1214
Score = 640 bits (1652), Expect = 0.0
Identities = 375/916 (40%), Positives = 534/916 (57%), Gaps = 22/916 (2%)
Frame = -1
Query: 2718 RLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLG 2539
R T+ + + ++ LI +Y+ RGH +AD DPL ++ A P+LE+ +GL
Sbjct: 339 RWSTDNPDSIVDKNARVMNLIAAYRNRGHLMADTDPLRLDKARFRSH--PDLEVLTHGLT 396
Query: 2538 ERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFE 2359
DLDR F + KK LR++L L+D YC GVEY H+ + EQ++W+ +R E
Sbjct: 397 LWDLDRVFKVDGFAGAQYKK---LRDVLGLLRDAYCRHIGVEYAHILDPEQKEWLEQRVE 453
Query: 2358 APRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSST 2179
V QK +L K L + FE FL K+ +KRF LEG E +IP M ID +
Sbjct: 454 TKHVKPTVAQQKYILSK-LNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAE 512
Query: 2178 LGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEPAD-EGSGDVKYHLGVCIERL 2005
G+D VIGMPHRGRLNVLAN+ +P + I ++F L P+ GSGDVKYHLG L
Sbjct: 513 HGLDEVVIGMPHRGRLNVLANIVGKPYSQIFTEFEGNLNPSQAHGSGDVKYHLGATGLYL 572
Query: 2004 NRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAE-------AFYAGDEKCDRTMAILLHGD 1846
++++++ ANPSHLEAVDPV+ G VRA+ + + ++ + ++LHGD
Sbjct: 573 QMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDHGSIDSDGQRAFSVVPLMLHGD 632
Query: 1845 AAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCP 1666
AAFAGQGVV ET NL +LP Y G IHI+VNNQIGFTT P SRSS YCTDV +++G P
Sbjct: 633 AAFAGQGVVAETLNLANLPGYRVGGTIHIIVNNQIGFTTAPEYSRSSEYCTDVAKMIGAP 692
Query: 1665 IFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIK 1486
IFHVN DDPEA + V +A D+R+ FKKDV++D++CYRR GHNE D+P T P MY +
Sbjct: 693 IFHVNGDDPEACVWVARLAVDFRQRFKKDVVIDMLCYRRRGHNEGDDPSMTNPYMYDVVD 752
Query: 1485 QTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTY--VRNRDWLDSPW 1312
+ A + Y E ++ G + + ++ L Y LE + +++ V+ + ++S
Sbjct: 753 TKRGARKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHGVQPSESVES-- 810
Query: 1311 DDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKDNSLDW 1132
+ P L +T F P GF H ++ L+ R++M + +DW
Sbjct: 811 ----DQMIPAGL-ATAVDKSLLARIGDAFLALPNGFTAHPRVQPVLEKRREMAYEGKIDW 865
Query: 1131 ACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPL------NDLS 970
A GE LA GSL+ EG VRLSGQD +RGTFS RH VL D+ ++ + PL +D S
Sbjct: 866 AFGELLALGSLVAEGKLVRLSGQDSRRGTFSQRHSVLIDRHTGEE-FTPLQLLATNSDGS 924
Query: 969 EGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQS 790
G++ V +S LSEYA +GFE GY++ +P+++V+WEAQFGDF N AQ IID+FISSG++
Sbjct: 925 PTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDAVVLWEAQFGDFVNGAQSIIDEFISSGEA 984
Query: 789 KWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDT 610
KW + S +V+LLPHG+EG GP+H+SAR ERFLQ+ E
Sbjct: 985 KWGQLSNVVLLLPHGHEGQGPDHTSARIERFLQLWAEG---------------------- 1022
Query: 609 NWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVI 430
+ +A +TP+N +HLLRR ++P +VF+PKS+LRH A S ++DF + F+ V+
Sbjct: 1023 SMTIAMPSTPSNYFHLLRRHALDGIQRPLIVFTPKSMLRHKAAVSEIKDF-TEIKFRSVL 1081
Query: 429 P----ETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLV 262
E G +N V R++ +GK+YY++ AARK ND+A+VR+EQL+P P +
Sbjct: 1082 EEPTYEDGIGDRN--KVSRILLTSGKLYYEL-AARKAKDNRNDLAIVRLEQLAPLPRRRL 1138
Query: 261 QQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNK 85
++ +Y+ E W QEE N GAW + LL K R S+P++G+
Sbjct: 1139 RETLDRYENVKEFFWVQEEPANQGAWPRFGLELPELLPDKLAGIKRISRRAMSAPSSGSS 1198
Query: 84 FTHMQEQKEMMSKVFG 37
H EQ+E++ + FG
Sbjct: 1199 KVHAVEQQEILDEAFG 1214
>gi|15608388|ref|NP_215764.1| sucA [Mycobacterium tuberculosis H37Rv]
gi|7478967|pir||G70953 probable sucA protein - Mycobacterium
tuberculosis (strain H37RV)
gi|2695834|emb|CAA15904.1| PROBABLE 2-OXOGLUTARATE DEHYDROGENASE SUCA
(Alpha-ketoglutarate dehydrogenase) [Mycobacterium
tuberculosis H37Rv]
Length = 1214
Score = 639 bits (1648), Expect = 0.0
Identities = 374/916 (40%), Positives = 534/916 (57%), Gaps = 22/916 (2%)
Frame = -1
Query: 2718 RLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLG 2539
R T+ + + ++ LI +Y+ RGH +AD DPL ++ A P+LE+ +GL
Sbjct: 339 RWSTDNPDSIVDKNARVMNLIAAYRNRGHLMADTDPLRLDKARFRSH--PDLEVLTHGLT 396
Query: 2538 ERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFE 2359
DLDR F + KK LR++L L+D YC GVEY H+ + EQ++W+ +R E
Sbjct: 397 LWDLDRVFKVDGFAGAQYKK---LRDVLGLLRDAYCRHIGVEYAHILDPEQKEWLEQRVE 453
Query: 2358 APRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSST 2179
V QK +L K L + FE FL K+ +KRF LEG E +IP M ID +
Sbjct: 454 TKHVKPTVAQQKYILSK-LNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAE 512
Query: 2178 LGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEPAD-EGSGDVKYHLGVCIERL 2005
G+D VIGMPHRGRLNVLAN+ +P + I ++F L P+ GSGDVKYHLG L
Sbjct: 513 HGLDEVVIGMPHRGRLNVLANIVGKPYSQIFTEFEGNLNPSQAHGSGDVKYHLGATGLYL 572
Query: 2004 NRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAE-------AFYAGDEKCDRTMAILLHGD 1846
++++++ ANPSHLEAVDPV+ G VRA+ + + ++ + ++LHGD
Sbjct: 573 QMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDHGSIDSDGQRAFSVVPLMLHGD 632
Query: 1845 AAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCP 1666
AAFAGQGVV ET NL +LP Y G IHI+VNNQIGFTT P SRSS YCTDV +++G P
Sbjct: 633 AAFAGQGVVAETLNLANLPGYRVGGTIHIIVNNQIGFTTAPEYSRSSEYCTDVAKMIGAP 692
Query: 1665 IFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIK 1486
IFHVN DDPEA + V +A D+R+ FKKDV++D++CYRR GHNE D+P T P +Y +
Sbjct: 693 IFHVNGDDPEACVWVARLAVDFRQRFKKDVVIDMLCYRRRGHNEGDDPSMTNPYVYDVVD 752
Query: 1485 QTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTY--VRNRDWLDSPW 1312
+ A + Y E ++ G + + ++ L Y LE + +++ V+ + ++S
Sbjct: 753 TKRGARKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHGVQPSESVES-- 810
Query: 1311 DDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKDNSLDW 1132
+ P L +T F P GF H ++ L+ R++M + +DW
Sbjct: 811 ----DQMIPAGL-ATAVDKSLLARIGDAFLALPNGFTAHPRVQPVLEKRREMAYEGKIDW 865
Query: 1131 ACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPL------NDLS 970
A GE LA GSL+ EG VRLSGQD +RGTFS RH VL D+ ++ + PL +D S
Sbjct: 866 AFGELLALGSLVAEGKLVRLSGQDSRRGTFSQRHSVLIDRHTGEE-FTPLQLLATNSDGS 924
Query: 969 EGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQS 790
G++ V +S LSEYA +GFE GY++ +P+++V+WEAQFGDF N AQ IID+FISSG++
Sbjct: 925 PTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDAVVLWEAQFGDFVNGAQSIIDEFISSGEA 984
Query: 789 KWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDT 610
KW + S +V+LLPHG+EG GP+H+SAR ERFLQ+ E
Sbjct: 985 KWGQLSNVVLLLPHGHEGQGPDHTSARIERFLQLWAEG---------------------- 1022
Query: 609 NWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVI 430
+ +A +TP+N +HLLRR ++P +VF+PKS+LRH A S ++DF + F+ V+
Sbjct: 1023 SMTIAMPSTPSNYFHLLRRHALDGIQRPLIVFTPKSMLRHKAAVSEIKDF-TEIKFRSVL 1081
Query: 429 P----ETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLV 262
E G +N V R++ +GK+YY++ AARK ND+A+VR+EQL+P P +
Sbjct: 1082 EEPTYEDGIGDRN--KVSRILLTSGKLYYEL-AARKAKDNRNDLAIVRLEQLAPLPRRRL 1138
Query: 261 QQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNK 85
++ +Y+ E W QEE N GAW + LL K R S+P++G+
Sbjct: 1139 RETLDRYENVKEFFWVQEEPANQGAWPRFGLELPELLPDKLAGIKRISRRAMSAPSSGSS 1198
Query: 84 FTHMQEQKEMMSKVFG 37
H EQ+E++ + FG
Sbjct: 1199 KVHAVEQQEILDEAFG 1214
>gi|46131254|ref|ZP_00169384.2| COG0567: 2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, and related
enzymes [Ralstonia eutropha JMP134]
Length = 923
Score = 639 bits (1648), Expect = 0.0
Identities = 380/967 (39%), Positives = 533/967 (54%), Gaps = 13/967 (1%)
Frame = -1
Query: 2913 IEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVT-- 2740
+E+ YEA+L+D +SV W YF ++ AG + P ++
Sbjct: 1 MEEQYEAYLKDRASVSDEWRGYFDALQQMPAVDGST--------AGDVAHGPIVSRFAEL 52
Query: 2739 TSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIP-PEL 2563
S PA A S+ HL +Q LI +Y+ G A LDPL +P PEL
Sbjct: 53 AKSPPAVGHPAGAGHASVRKHLAVQALIAAYRMVGSRNAHLDPLRWTVR-----VPLPEL 107
Query: 2562 ELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQ 2383
+YGL DLD FLL F E +TLR ++Q L++ Y + G E+MHL + +Q+
Sbjct: 108 SPGYYGLFRSDLDARFLLSDANFADE--DMTLRHLMQALEETYSGTLGAEFMHLADPKQR 165
Query: 2382 DWIRRRFEAPRV-TELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAM 2206
W + R E+ R T L K+ + +RL + E +L ++ +KRF LEG E LI +
Sbjct: 166 SWWQMRLESTRARTHLDDGNKRHILERLTAAEGLERYLHARYVGQKRFSLEGGESLIVLL 225
Query: 2205 KQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVKYHL 2026
+++ +T G+ S ++GM HRGR+NVL NV +P A + +F +GDVKYH
Sbjct: 226 DELVAYGATQGIRSAILGMAHRGRINVLVNVVGKPPAALFDEFEGKTADRLPAGDVKYHK 285
Query: 2025 GVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGD 1846
G R + ++ + NPSHLE V+PVV G RA A G + + +HGD
Sbjct: 286 G--FTGTLRTASGPAEVTLAFNPSHLEIVNPVVQGMARARAEVLG-LGMGAVLPVEIHGD 342
Query: 1845 AAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTT-DPRSSRSSPYCTDVGRVVGC 1669
A+ +GQG+V+ET NL + T G +H+VVNNQ+GFTT DPR +RS+ YCTD+ +++
Sbjct: 343 ASISGQGIVMETMNLSGTRGHGTGGTVHVVVNNQVGFTTSDPRDARSTFYCTDIAKMIEA 402
Query: 1668 PIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRI 1489
P+ HVN DDPEAV+ +A D+R TF K V+++L+C+RRHGH E D P TQPLMY+ I
Sbjct: 403 PVLHVNGDDPEAVVAATRLAVDYRMTFGKSVVIELMCFRRHGHQEQDTPAITQPLMYRSI 462
Query: 1488 KQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWD 1309
+ Y EK+++EGV V+ +Y + L+ A R SP D
Sbjct: 463 AEHPGVRAIYAEKLVDEGVVTAADVERYAREYRARLDAAQGGKDDKPSADMRLEASSPQD 522
Query: 1308 DFFKKRDPLKLPSTGXXXXXXXXXIG---KFSQYPEGFNLHRGLERTLKGRQQMLKD-NS 1141
K P G G K + P G LH + R + R++M +
Sbjct: 523 SGNSKTQP------GYATPGREMLKGLALKITDIPAGHTLHPLVARVISARREMAEGARP 576
Query: 1140 LDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVD---QKIYNPLNDLS 970
LDW E LAF SLL G+ VRLSGQD +RGTF HRH VLHDQK + Q Y PL+ +S
Sbjct: 577 LDWGMAEHLAFASLLSAGVGVRLSGQDSERGTFGHRHAVLHDQKREMRGQGTYIPLDHVS 636
Query: 969 EGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQS 790
+ Q ++V NS LSE AVL FE GYS+ +SLV+WEAQFGDF+N AQ +ID F+S+G +
Sbjct: 637 DDQARFSVTNSILSEAAVLAFEYGYSLFRKDSLVLWEAQFGDFANGAQVVIDNFLSAGAA 696
Query: 789 KWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDT 610
KW + SG+ +LLPHG EG GPEH+SAR ER+LQ+C ++
Sbjct: 697 KWGQHSGVTLLLPHGQEGQGPEHASARLERYLQLCAQE---------------------- 734
Query: 609 NWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVI 430
N V TTPA ++HLLR Q T R P VV +PKSLLRH A S +++ +G F+ V+
Sbjct: 735 NMRVCQPTTPAQMFHLLRLQATRNDRIPLVVMTPKSLLRHQEAVSTLDELATG-EFREVL 793
Query: 429 PETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQEC 250
E G Q + R++ C+GKVY+D++A R+ GK+N +AL+RVEQL PFP + +E
Sbjct: 794 AE-GRSEQEEDRITRLILCSGKVYFDLLARRRKSGKDN-IALLRVEQLYPFPEQQIAREL 851
Query: 249 RKYQG-AEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHM 73
+Y E++W QEE +N GAWSFV R+ ++ D +Y G ++S A G H
Sbjct: 852 DRYPYLKEVIWCQEEARNQGAWSFVVERLQGIVE-DPLVLRYVGPEAAASTAPGYASMHA 910
Query: 72 QEQKEMM 52
Q+ +
Sbjct: 911 ARQESTL 917
>gi|15840693|ref|NP_335730.1| 2-oxoglutarate dehydrogenase E1
component [Mycobacterium tuberculosis CDC1551]
gi|13880881|gb|AAK45544.1| 2-oxoglutarate dehydrogenase E1 component
[Mycobacterium tuberculosis CDC1551]
Length = 1231
Score = 639 bits (1648), Expect = 0.0
Identities = 374/916 (40%), Positives = 534/916 (57%), Gaps = 22/916 (2%)
Frame = -1
Query: 2718 RLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLG 2539
R T+ + + ++ LI +Y+ RGH +AD DPL ++ A P+LE+ +GL
Sbjct: 356 RWSTDNPDSIVDKNARVMNLIAAYRNRGHLMADTDPLRLDKARFRSH--PDLEVLTHGLT 413
Query: 2538 ERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFE 2359
DLDR F + KK LR++L L+D YC GVEY H+ + EQ++W+ +R E
Sbjct: 414 LWDLDRVFKVDGFAGAQYKK---LRDVLGLLRDAYCRHIGVEYAHILDPEQKEWLEQRVE 470
Query: 2358 APRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSST 2179
V QK +L K L + FE FL K+ +KRF LEG E +IP M ID +
Sbjct: 471 TKHVKPTVAQQKYILSK-LNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAE 529
Query: 2178 LGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFS-TLEPAD-EGSGDVKYHLGVCIERL 2005
G+D VIGMPHRGRLNVLAN+ +P + I ++F L P+ GSGDVKYHLG L
Sbjct: 530 HGLDEVVIGMPHRGRLNVLANIVGKPYSQIFTEFEGNLNPSQAHGSGDVKYHLGATGLYL 589
Query: 2004 NRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAE-------AFYAGDEKCDRTMAILLHGD 1846
++++++ ANPSHLEAVDPV+ G VRA+ + + ++ + ++LHGD
Sbjct: 590 QMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDHGSIDSDGQRAFSVVPLMLHGD 649
Query: 1845 AAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCP 1666
AAFAGQGVV ET NL +LP Y G IHI+VNNQIGFTT P SRSS YCTDV +++G P
Sbjct: 650 AAFAGQGVVAETLNLANLPGYRVGGTIHIIVNNQIGFTTAPEYSRSSEYCTDVAKMIGAP 709
Query: 1665 IFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIK 1486
IFHVN DDPEA + V +A D+R+ FKKDV++D++CYRR GHNE D+P T P +Y +
Sbjct: 710 IFHVNGDDPEACVWVARLAVDFRQRFKKDVVIDMLCYRRRGHNEGDDPSMTNPYVYDVVD 769
Query: 1485 QTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTY--VRNRDWLDSPW 1312
+ A + Y E ++ G + + ++ L Y LE + +++ V+ + ++S
Sbjct: 770 TKRGARKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHGVQPSESVES-- 827
Query: 1311 DDFFKKRDPLKLPSTGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKDNSLDW 1132
+ P L +T F P GF H ++ L+ R++M + +DW
Sbjct: 828 ----DQMIPAGL-ATAVDKSLLARIGDAFLALPNGFTAHPRVQPVLEKRREMAYEGKIDW 882
Query: 1131 ACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPL------NDLS 970
A GE LA GSL+ EG VRLSGQD +RGTFS RH VL D+ ++ + PL +D S
Sbjct: 883 AFGELLALGSLVAEGKLVRLSGQDSRRGTFSQRHSVLIDRHTGEE-FTPLQLLATNSDGS 941
Query: 969 EGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQS 790
G++ V +S LSEYA +GFE GY++ +P+++V+WEAQFGDF N AQ IID+FISSG++
Sbjct: 942 PTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDAVVLWEAQFGDFVNGAQSIIDEFISSGEA 1001
Query: 789 KWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDT 610
KW + S +V+LLPHG+EG GP+H+SAR ERFLQ+ E
Sbjct: 1002 KWGQLSNVVLLLPHGHEGQGPDHTSARIERFLQLWAEG---------------------- 1039
Query: 609 NWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVI 430
+ +A +TP+N +HLLRR ++P +VF+PKS+LRH A S ++DF + F+ V+
Sbjct: 1040 SMTIAMPSTPSNYFHLLRRHALDGIQRPLIVFTPKSMLRHKAAVSEIKDF-TEIKFRSVL 1098
Query: 429 P----ETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLV 262
E G +N V R++ +GK+YY++ AARK ND+A+VR+EQL+P P +
Sbjct: 1099 EEPTYEDGIGDRN--KVSRILLTSGKLYYEL-AARKAKDNRNDLAIVRLEQLAPLPRRRL 1155
Query: 261 QQECRKYQGA-EILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNK 85
++ +Y+ E W QEE N GAW + LL K R S+P++G+
Sbjct: 1156 RETLDRYENVKEFFWVQEEPANQGAWPRFGLELPELLPDKLAGIKRISRRAMSAPSSGSS 1215
Query: 84 FTHMQEQKEMMSKVFG 37
H EQ+E++ + FG
Sbjct: 1216 KVHAVEQQEILDEAFG 1231
>gi|46446724|ref|YP_008089.1| probable 2-oxoglutarate dehydrogenase E1
component, sucA [Parachlamydia sp. UWE25]
gi|46400365|emb|CAF23814.1| probable 2-oxoglutarate dehydrogenase E1
component, sucA [Parachlamydia sp. UWE25]
Length = 890
Score = 637 bits (1644), Expect = 0.0
Identities = 376/971 (38%), Positives = 548/971 (55%), Gaps = 13/971 (1%)
Frame = -1
Query: 2913 IEQMYEAWLQDPSSVHTSWDAYFRNVEXXXXXXXXXXXXXXXAYAGALGVSPAAAQVTTS 2734
+E +Y+ + + S+ SW YF+ +E T S
Sbjct: 17 LENLYQDYQKKYDSLDPSWHRYFQELE------------------------------TAS 46
Query: 2733 SAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELS 2554
S T +++S + DH+ I +L R GH I+ ++P+ +N + ++ L+
Sbjct: 47 SFTTTNKQSSSS--NHVDHV-IDVLRRD----GHLISSVNPISLNPSSFTFSLTEYLKPC 99
Query: 2553 FYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWI 2374
+D + ++ + F + L+ IYC G EY HLN+ + + WI
Sbjct: 100 --------VDTQAIIQTSKF-------------EYLRKIYCDRIGFEYKHLNDKKMEVWI 138
Query: 2373 RRRFEAPRVTE-LSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQV 2197
+ E + L+ +QK+ + L RS FE FL K+ +KRF LEG E LIP + +
Sbjct: 139 QDFIEQQFFKQTLTKEQKQHVLACLSRSELFETFLHTKYIGQKRFSLEGAETLIPMLDLL 198
Query: 2196 IDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFST--LEPADEGSGDVKYHLG 2023
I++ + GV F++GM HRGRLNVLAN+ + L TI S+F + + EG GDVKYH G
Sbjct: 199 IEAGAEQGVQEFLVGMAHRGRLNVLANILNKSLDTIFSEFGEEYIPTSLEGMGDVKYHKG 258
Query: 2022 VCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKC-DRTMAILLHGD 1846
E++ + K++KI++ NPSHLE+V+ VV GK RA+ F AG EK + + IL+HGD
Sbjct: 259 YTGEKIKTRLGKSIKISLSPNPSHLESVNAVVEGKTRAKQFLAGGEKARKKIIPILIHGD 318
Query: 1845 AAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCP 1666
AA +GQGVV ET L L Y T G IH V+NNQIGFTT PR RS+ YCTD+ R G P
Sbjct: 319 AAVSGQGVVYETLQLSQLKGYETGGTIHFVINNQIGFTTIPRDLRSTRYCTDIARAFGLP 378
Query: 1665 IFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIK 1486
IFHVN +DP++ + V +A + R+ F DV +DL YR++GHNE DEP +TQPL + IK
Sbjct: 379 IFHVNAEDPDSCVQVTLLALEIRQRFHCDVFIDLNGYRKYGHNEGDEPAYTQPLECRLIK 438
Query: 1485 QTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDD 1306
++ + Y +++L +G+ + Q + + Y + L + +E ++ P
Sbjct: 439 GKQSIRKMYYDQLLVQGILDPQMMDQLEAAYKAGLREVHEK------------INQPQAI 486
Query: 1305 FFKKRDPLKLP-------STGXXXXXXXXXIGKFSQYPEGFNLHRGLERTLKGRQQMLKD 1147
+ P +P TG +FSQ P+GF LH ++ +K R + +K+
Sbjct: 487 SSVVKQPFSIPQSFFQSVETGVNLEKLISLAERFSQIPQGFTLHPKVDYLVKERLRQVKE 546
Query: 1146 NSL-DWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLS 970
N L DW E LA+ SLL+EG+ +R+SGQD RGTFSHRH + DQ +K Y PL L
Sbjct: 547 NKLIDWGLAEHLAYASLLEEGVSIRISGQDCCRGTFSHRHAIWVDQHT-EKDYYPLAHLK 605
Query: 969 EGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQS 790
+GQG++ + NS LSE AVLGFE GYS+V L +WEAQFGDF+N AQ IIDQFI+S +
Sbjct: 606 QGQGKFEIVNSPLSEMAVLGFEYGYSVVCVKGLNVWEAQFGDFNNGAQIIIDQFIASAEQ 665
Query: 789 KWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDT 610
KW ++SGL++ LPHG EG GPEHSS R ERFL + D
Sbjct: 666 KWGQKSGLILFLPHGLEGQGPEHSSGRLERFLTLAGHD---------------------- 703
Query: 609 NWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVI 430
N + N TTPA +HLLRRQV F KP +VF+PK LLR+P S + +F G+ F+ +I
Sbjct: 704 NLQIVNTTTPAQFFHLLRRQVKHQFEKPLIVFTPKGLLRYPKCVSALHEFTQGT-FREII 762
Query: 429 PETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQEC 250
+ A NP ++KR+V C+G++YYD++A R+ + + ++ +R+EQL P + +++
Sbjct: 763 DDVFA---NPSEIKRLVLCSGRIYYDLLAEREKL-NQKEIGFIRIEQLYPLHMEELKKLI 818
Query: 249 RKYQG-AEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHM 73
+Y E++WAQEE +NMGAWSF+ P +N L+S Y GR S++PATG+ H
Sbjct: 819 FQYPHIQEVVWAQEEPQNMGAWSFMFPYLNELIS-SSIQLSYVGRERSATPATGSYCLHN 877
Query: 72 QEQKEMMSKVF 40
QE ++ +VF
Sbjct: 878 QEHANILKQVF 888