Homology by BLASTX


BLASTX 2.2.4 [Aug-26-2002]
Query= Y71H10A_3
         (2346 letters)

Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
           1,967,186 sequences; 661,712,633 total letters


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|25147587|ref|NP_741739.1| phosphofructokinase (XD563) [Caenor...  1520   0.0
gi|25147584|ref|NP_741738.1| phosphofructokinase (89.7 kD) (XD56...  1513   0.0
gi|7510438|pir||T33481 hypothetical protein Y71H10A.1 - Caenorha...  1503   0.0
gi|39591033|emb|CAE58813.1| Hypothetical protein CBG02020 [Caeno...  1436   0.0
gi|38304370|gb|AAR16088.1| phosphofructokinase [Ascaris suum]        1087   0.0
gi|3122304|sp|Q27665|K6PF_HAECO 6-phosphofructokinase (Phosphofr...  1083   0.0
gi|28573326|ref|NP_724891.2| CG4001-PC [Drosophila melanogaster]...   894   0.0
gi|17647809|ref|NP_523676.1| CG4001-PA [Drosophila melanogaster]...   894   0.0
gi|24652337|ref|NP_724890.1| CG4001-PB [Drosophila melanogaster]...   892   0.0
gi|31198559|ref|XP_308227.1| ENSANGP00000021523 [Anopheles gambi...   882   0.0
gi|34868102|ref|XP_346813.1| hypothetical protein XP_346812 [Rat...   829   0.0
gi|13638207|sp|P47857|K6PF_MOUSE 6-phosphofructokinase, muscle t...   828   0.0
gi|31981185|ref|NP_067489.2| phosphofructokinase, muscle; phosph...   826   0.0
gi|28557063|dbj|BAC57529.1| muscle-type phosphofructokinase [Equ...   826   0.0
gi|227448|prf||1704126A phosphofructokinase                           824   0.0
gi|33303855|gb|AAQ02441.1| phosphofructokinase, muscle [syntheti...   824   0.0
gi|4505749|ref|NP_000280.1| phosphofructokinase, muscle; Phospho...   824   0.0
gi|1708593|sp|P52784|K6PF_CANFA 6-phosphofructokinase, muscle ty...   823   0.0
gi|34532659|dbj|BAC86498.1| unnamed protein product [Homo sapiens]    821   0.0
gi|13929002|ref|NP_113903.1| phosphofructokinase, muscle; phosph...   820   0.0
gi|125128|sp|P00511|K6PF_RABIT 6-phosphofructokinase, muscle typ...   818   0.0
gi|1363065|pir||A53206 6-phosphofructokinase (EC 2.7.1.11) C - r...   814   0.0
gi|1346356|sp|P47859|K6PP_RABIT 6-phosphofructokinase, type C (P...   813   0.0
gi|33303967|gb|AAQ02491.1| phosphofructokinase, platelet [synthe...   811   0.0
gi|11321601|ref|NP_002618.1| phosphofructokinase, platelet; Phos...   811   0.0
gi|34784595|gb|AAH57710.1| MGC68847 protein [Xenopus laevis]          809   0.0
gi|23821298|dbj|BAC20931.1| phosphofructokinase [Gallus gallus]       805   0.0
gi|31560653|ref|NP_032852.2| phosphofructokinase, liver, B-type ...   805   0.0
gi|6981352|ref|NP_037322.1| phosphofructokinase, liver, B-type [...   804   0.0
gi|35431|emb|CAA33597.1| unnamed protein product [Homo sapiens]       804   0.0
gi|38197562|gb|AAH61791.1| Phosphofructokinase, liver, B-type [R...   804   0.0
gi|45361279|ref|NP_989217.1| hypothetical protein MGC75635 [Xeno...   803   0.0
gi|33303747|gb|AAQ02387.1| phosphofructokinase, liver [synthetic...   803   0.0
gi|48762920|ref|NP_002617.3| liver phosphofructokinase isoform b...   803   0.0
gi|125127|sp|P12382|K6PL_MOUSE 6-phosphofructokinase, liver type...   802   0.0
gi|26345672|dbj|BAC36487.1| unnamed protein product [Mus musculus]    802   0.0
gi|105155|pir||A33639 6-phosphofructokinase (EC 2.7.1.11), hepat...   801   0.0
gi|9988057|sp|P17858|K6PL_HUMAN 6-phosphofructokinase, liver typ...   801   0.0
gi|14286326|gb|AAH08964.1| Liver phosphofructokinase [Homo sapie...   799   0.0
gi|5441456|emb|CAB46744.1| pfk_CDS [Homo sapiens]                     797   0.0
gi|26347093|dbj|BAC37195.1| unnamed protein product [Mus musculus]    795   0.0
gi|9790051|ref|NP_062677.1| phosphofructokinase, platelet; ATP:D...   794   0.0
gi|50414585|gb|AAH77756.1| Unknown (protein for MGC:79063) [Xeno...   794   0.0
gi|8489537|gb|AAF75700.1| phosphofructokinase-1 C isozyme [Mus m...   792   0.0
gi|45383682|ref|NP_989554.1| liver phosphofructokinase [Gallus g...   790   0.0
gi|1346357|sp|P47860|K6PP_RAT 6-phosphofructokinase, type C (Pho...   786   0.0
gi|50346005|ref|NP_001002021.1| liver phosphofructokinase isofor...   785   0.0
gi|1083579|pir||A53047 6-phosphofructokinase (EC 2.7.1.11) - rat...   783   0.0
gi|3122305|sp|Q27778|K6PF_SCHMA 6-phosphofructokinase (Phosphofr...   780   0.0
gi|39644779|gb|AAH07798.2| PFKM protein [Homo sapiens]                760   0.0
gi|47226320|emb|CAG09288.1| unnamed protein product [Tetraodon n...   746   0.0
gi|50732643|ref|XP_425972.1| PREDICTED: similar to MGC68847 prot...   730   0.0
gi|1708594|sp|P52034|K6PF_DROME 6-phosphofructokinase (Phosphofr...   729   0.0
gi|47225149|emb|CAF98776.1| unnamed protein product [Tetraodon n...   722   0.0
gi|47228737|emb|CAG07469.1| unnamed protein product [Tetraodon n...   665   0.0
gi|25009881|gb|AAN71109.1| AT27295p [Drosophila melanogaster]         637   0.0
gi|32408657|ref|XP_324809.1| hypothetical protein [Neurospora cr...   597   e-169
gi|50843700|ref|YP_056927.1| 6-phosphofructokinase, type C [Prop...   596   e-169
gi|46135881|ref|XP_389632.1| hypothetical protein FG09456.1 [Gib...   586   e-166
gi|19112738|ref|NP_595946.1| 6-phosphofructokinase beta subunit ...   582   e-164
gi|49091798|ref|XP_407360.1| K6PF_ASPNG 6-phosphofructokinase (P...   572   e-161
gi|30913122|sp|Q9HGZ1|K6P1_ASPOR 6-phosphofructokinase alpha sub...   570   e-161
gi|48257221|gb|AAH18295.2| PFKL protein [Homo sapiens]                570   e-161
gi|28830002|gb|AAO52492.1| similar to Dictyostelium discoideum (...   568   e-160
gi|1495369|emb|CAA61438.1| 6-phosphofructokinase [Dictyostelium ...   565   e-159
gi|3122299|sp|P90521|K6PF_DICDI 6-phosphofructokinase (Phosphofr...   561   e-158
gi|50293647|ref|XP_449235.1| unnamed protein product [Candida gl...   560   e-158
gi|17366234|sp|O94200|K6P2_CANAL 6-phosphofructokinase beta subu...   560   e-158
gi|46442755|gb|EAL02042.1| hypothetical protein CaO19.13893 [Can...   560   e-158
gi|3024061|sp|P78985|K6PF_ASPNG 6-phosphofructokinase (Phosphofr...   557   e-157
gi|2499487|sp|Q92448|K6P1_PICPA 6-phosphofructokinase (Phosphofr...   554   e-156
gi|45198336|ref|NP_985365.1| AFL185Wp [Eremothecium gossypii] >g...   553   e-156
gi|46443818|gb|EAL03097.1| hypothetical protein CaO19.3967 [Cand...   552   e-155
gi|17366237|sp|O94201|K6P1_CANAL 6-phosphofructokinase alpha sub...   552   e-155
gi|21262975|gb|AAM44819.1| 6-phosphofructo-1-kinase alpha-subuni...   551   e-155
gi|6323861|ref|NP_013932.1| phosphofructokinase beta subunit; Pf...   551   e-155
gi|172140|gb|AAA34860.1| phosphofructokinase, beta subunit [Sacc...   551   e-155
gi|38100255|gb|EAA47410.1| hypothetical protein MG02653.4 [Magna...   550   e-155
gi|50287777|ref|XP_446318.1| unnamed protein product [Candida gl...   548   e-154
gi|50302619|ref|XP_451245.1| K6P1_KLULA [Kluyveromyces lactis] >...   548   e-154
gi|47228140|emb|CAF97769.1| unnamed protein product [Tetraodon n...   548   e-154
gi|50310683|ref|XP_455363.1| K6P2_KLULA [Kluyveromyces lactis] >...   546   e-153
gi|48143910|ref|XP_393657.1| similar to ENSANGP00000021523 [Apis...   545   e-153
gi|50255583|gb|EAL18316.1| hypothetical protein CNBJ2390 [Crypto...   544   e-153
gi|417202|sp|Q03216|K6P2_KLULA 6-phosphofructokinase beta subuni...   541   e-152
gi|19424735|gb|AAL82590.2| 6-phosphofructo-1-kinase beta-subunit...   540   e-152
gi|6321679|ref|NP_011756.1| phosphofructokinase alpha subunit; P...   535   e-150
gi|49071676|ref|XP_400127.1| hypothetical protein UM02512.1 [Ust...   534   e-150
gi|45190399|ref|NP_984653.1| AEL208Wp [Eremothecium gossypii] >g...   528   e-148
gi|50420741|ref|XP_458908.1| unnamed protein product [Debaryomyc...   527   e-148
gi|17558788|ref|NP_505457.1| 6-phosphofructokinase family member...   525   e-147
gi|39594462|emb|CAE72040.1| Hypothetical protein CBG19122 [Caeno...   523   e-146
gi|50427665|ref|XP_462445.1| unnamed protein product [Debaryomyc...   521   e-146
gi|50550849|ref|XP_502897.1| YlPFK1 [Yarrowia lipolytica] >gnl|B...   515   e-144
gi|50290131|ref|XP_447497.1| unnamed protein product [Candida gl...   501   e-140
gi|30913121|sp|Q9HGZ0|K6P2_ASPOR 6-phosphofructokinase beta subu...   492   e-137
gi|47229554|emb|CAG06750.1| unnamed protein product [Tetraodon n...   483   e-135
gi|38197069|gb|AAH04920.2| PFKL protein [Homo sapiens]                474   e-132
gi|975290|gb|AAA91985.1| phosphofructokinase >gnl|BL_ORD_ID|1153...   448   e-124
gi|26326863|dbj|BAC27175.1| unnamed protein product [Mus musculus]    441   e-122
gi|18204967|gb|AAH21698.1| Similar to phosphofructokinase, plate...   426   e-117
gi|189857|gb|AAA79220.1| phosphofructokinase                          402   e-110
gi|2344769|dbj|BAA21891.1| phosphofructokinase-P [Homo sapiens]       386   e-105
gi|22974363|ref|ZP_00020637.1| hypothetical protein [Chloroflexu...   373   e-101
gi|189853|gb|AAA36435.1| phosphofructokinase                          293   1e-77
gi|12860934|dbj|BAB32082.1| unnamed protein product [Mus musculus]    278   4e-73
gi|19173028|ref|NP_597579.1| 6-PHOSPHOFRUCTOKINASE (PHOSPHOFRUCT...   272   2e-71
gi|4433295|dbj|BAA21012.1| mouse PFK-M [Mus musculus]                 249   2e-64
gi|2499486|sp|Q27543|K6PF_CALFI 6-phosphofructokinase (Phosphofr...   248   6e-64
gi|1083454|pir||S53317 6-phosphofructokinase (EC 2.7.1.11) M - m...   247   8e-64
gi|4433358|dbj|BAA21013.1| rat PFK-M [Rattus norvegicus]              247   8e-64
gi|1085579|pir||S53318 6-phosphofructokinase (EC 2.7.1.11) M - r...   245   4e-63
gi|22971328|ref|ZP_00018298.1| hypothetical protein [Chloroflexu...   236   2e-60
gi|31873394|emb|CAD97688.1| hypothetical protein [Homo sapiens]       234   7e-60
gi|34364969|emb|CAE46026.1| hypothetical protein [Homo sapiens]       234   7e-60
gi|15642982|ref|NP_228024.1| 6-phosphofructokinase [Thermotoga m...   219   2e-55
gi|7492340|pir||T42087 probable 6-phosphofructokinase (EC 2.7.1....   218   4e-55
gi|29347472|ref|NP_810975.1| 6-phosphofructokinase [Bacteroides ...   216   2e-54
gi|29346512|ref|NP_810015.1| 6-phosphofructokinase [Bacteroides ...   214   6e-54
gi|45531823|ref|ZP_00182850.1| COG0205: 6-phosphofructokinase [E...   214   1e-53
gi|27573982|pdb|1MTO|A Chain A, X-Ray Crystal Structure Of A Pho...   207   7e-52
gi|125125|sp|P00512|K6PF_BACST 6-phosphofructokinase (Phosphofru...   207   7e-52
gi|230908|pdb|3PFK|  Phosphofructokinase (E.C.2.7.1.11) >gnl|BL_...   207   7e-52
gi|46909399|gb|AAT06217.1| phosphofructokinase [Chaetopterus sp....   207   1e-51
gi|20808233|ref|NP_623404.1| 6-phosphofructokinase [Thermoanaero...   205   3e-51
gi|46909409|gb|AAT06222.1| phosphofructokinase [Eucidaris tribul...   205   5e-51
gi|47229555|emb|CAG06751.1| unnamed protein product [Tetraodon n...   204   6e-51
gi|15615726|ref|NP_244030.1| 6-phosphofructokinase [Bacillus hal...   203   2e-50
gi|48854603|ref|ZP_00308765.1| COG0205: 6-phosphofructokinase [C...   203   2e-50
gi|46909427|gb|AAT06231.1| phosphofructokinase [Strongylocentrot...   202   2e-50
gi|46909411|gb|AAT06223.1| phosphofructokinase [Lestes congener]      202   4e-50
gi|49486524|ref|YP_043745.1| 6-phosphofructokinase [Staphylococc...   202   4e-50
gi|49483940|ref|YP_041164.1| 6-phosphofructokinase [Staphylococc...   201   5e-50
gi|32129675|sp|Q8CS68|K6PF_STAEP 6-phosphofructokinase (Phosphof...   201   5e-50
gi|46199899|ref|YP_005566.1| 6-phosphofructokinase isozyme 1 [Th...   201   7e-50
gi|41057052|ref|NP_957655.1| putative ATP-dependent 6-phosphofru...   201   7e-50
gi|125120|sp|P21777|K6P1_THETH 6-phosphofructokinase isozyme 1 (...   201   7e-50
gi|42524743|ref|NP_970123.1| unnamed protein product [Bdellovibr...   200   1e-49
gi|48845240|ref|ZP_00299525.1| COG0205: 6-phosphofructokinase [G...   200   1e-49
gi|46909419|gb|AAT06227.1| phosphofructokinase [Stylochus sp. KJ...   200   1e-49
gi|16079971|ref|NP_390797.1| 6-phosphofructokinase [Bacillus sub...   199   2e-49
gi|19703752|ref|NP_603314.1| 6-phosphofructokinase [Fusobacteriu...   199   2e-49
gi|30923315|sp|Q8RG98|K6PF_FUSNN 6-phosphofructokinase (Phosphof...   199   2e-49
gi|21402642|ref|NP_658627.1| PFK, Phosphofructokinase [Bacillus ...   199   3e-49
gi|46909413|gb|AAT06224.1| phosphofructokinase [Nucula proxima]       199   3e-49
gi|30022675|ref|NP_834306.1| 6-phosphofructokinase [Bacillus cer...   198   4e-49
gi|46909421|gb|AAT06228.1| phosphofructokinase [Mytilus californ...   197   7e-49
gi|39997166|ref|NP_953117.1| 6-phosphofructokinase [Geobacter su...   197   1e-48
gi|48860376|ref|ZP_00314301.1| COG0205: 6-phosphofructokinase [C...   197   1e-48
gi|46909395|gb|AAT06215.1| phosphofructokinase [Antedon mediterr...   196   2e-48
gi|46909407|gb|AAT06221.1| phosphofructokinase [Enallagma aspersum]   196   2e-48
gi|16800674|ref|NP_470942.1| lin1606 [Listeria innocua Clip11262...   196   2e-48
gi|16803611|ref|NP_465096.1| highly similar to 6-phosphofructoki...   196   2e-48
gi|46909397|gb|AAT06216.1| phosphofructokinase [Asterina miniata]     196   2e-48
gi|46909425|gb|AAT06230.1| phosphofructokinase [Mytilus edulis]       195   5e-48
gi|28212072|ref|NP_783016.1| 6-phosphofructokinase [Clostridium ...   194   6e-48
gi|23111329|ref|ZP_00097007.1| COG0205: 6-phosphofructokinase [D...   194   6e-48
gi|46909405|gb|AAT06220.1| phosphofructokinase [Encope michelini]     194   1e-47
gi|3122306|sp|Q59214|K6PF_BACMC 6-phosphofructokinase (Phosphofr...   193   2e-47
gi|50591025|ref|ZP_00332357.1| COG0205: 6-phosphofructokinase [S...   192   2e-47
gi|15601934|ref|NP_245006.1| PfkA [Pasteurella multocida Pm70] >...   191   5e-47
gi|46909401|gb|AAT06218.1| phosphofructokinase [Clypeatula coope...   191   7e-47
gi|23099627|ref|NP_693093.1| 6-phosphofructokinase [Oceanobacill...   191   9e-47
gi|46909429|gb|AAT06232.1| phosphofructokinase [Ptychodera flava]     190   1e-46
gi|46909423|gb|AAT06229.1| phosphofructokinase [Modiolus america...   190   2e-46
gi|16120429|ref|NP_403742.1| 6-phosphofructokinase [Yersinia pes...   189   3e-46
gi|18309343|ref|NP_561277.1| phosphofructokinase [Clostridium pe...   189   3e-46
gi|46909403|gb|AAT06219.1| phosphofructokinase [Dendraster excen...   187   7e-46
gi|15893808|ref|NP_347157.1| 6-phosphofructokinase [Clostridium ...   186   2e-45
gi|1905946|gb|AAB50189.1| phosphofructokinase                         186   2e-45
gi|13629168|sp|Q9KNP2|K6PF_VIBCH 6-phosphofructokinase (Phosphof...   185   4e-45
gi|15642684|ref|NP_232317.1| 6-phosphofructokinase, isozyme I [V...   185   4e-45
gi|27364658|ref|NP_760186.1| 6-phosphofructokinase [Vibrio vulni...   185   5e-45
gi|37681294|ref|NP_935903.1| 6-phosphofructokinase [Vibrio vulni...   185   5e-45
gi|46909417|gb|AAT06226.1| phosphofructokinase [Metridium senile]     185   5e-45
gi|15924688|ref|NP_372222.1| 6-phosphofructokinase [Staphylococc...   184   6e-45
gi|46911875|emb|CAG18673.1| putative 6-phosphofructokinase [Phot...   184   6e-45
gi|27468292|ref|NP_764929.1| 6-phosphofructokinase [Staphylococc...   184   8e-45
gi|50123227|ref|YP_052394.1| 6-phosphofructokinase isozyme I [Er...   184   8e-45
gi|28899629|ref|NP_799234.1| 6-phosphofructokinase, isozyme I [V...   183   1e-44
gi|49235020|ref|ZP_00329097.1| COG0205: 6-phosphofructokinase [M...   183   1e-44
gi|34762297|ref|ZP_00143301.1| 6-phosphofructokinase [Fusobacter...   183   1e-44
gi|30913101|sp|Q93LR4|K6PF_BACSH 6-phosphofructokinase (Phosphof...   183   2e-44
gi|16272920|ref|NP_439145.1| 6-phosphofructokinase [Haemophilus ...   183   2e-44
gi|23466424|ref|ZP_00122012.1| COG0205: 6-phosphofructokinase [H...   182   4e-44
gi|48824659|ref|ZP_00286008.1| COG0205: 6-phosphofructokinase [E...   181   7e-44
gi|42630182|ref|ZP_00155726.1| COG0205: 6-phosphofructokinase [H...   181   9e-44
gi|13124328|sp|Q9Z6C3|K6PF_ENTCL 6-phosphofructokinase (Phosphof...   180   1e-43
gi|24115211|ref|NP_709721.1| 6-phosphofructokinase I [Shigella f...   180   1e-43
gi|26250681|ref|NP_756721.1| 6-phosphofructokinase isozyme I [Es...   180   1e-43
gi|230661|pdb|2PFK|D Chain D, Phosphofructokinase (E.C.2.7.1.11)      179   3e-43
gi|230660|pdb|2PFK|C Chain C, Phosphofructokinase (E.C.2.7.1.11)      179   3e-43
gi|15804505|ref|NP_290545.1| 6-phosphofructokinase I [Escherichi...   179   3e-43
gi|32129687|sp|Q8FBD0|K6PF_ECOL6 6-phosphofructokinase (Phosphof...   179   3e-43
gi|399697|gb|AAB27539.1| phosphofructokinase, PFK {EC 2.7.1.11} ...   178   5e-43
gi|16762372|ref|NP_457989.1| 6-phosphofructokinase [Salmonella e...   178   5e-43
gi|32035193|ref|ZP_00135227.1| COG0205: 6-phosphofructokinase [A...   177   8e-43
gi|15673315|ref|NP_267489.1| 6-phosphofructokinase [Lactococcus ...   177   1e-42
gi|30064790|ref|NP_838961.1| 6-phosphofructokinase I [Shigella f...   177   1e-42
gi|13629322|sp|Q9RWN1|K6PF_DEIRA 6-phosphofructokinase (Phosphof...   177   1e-42
gi|48870732|ref|ZP_00323451.1| COG0205: 6-phosphofructokinase [P...   177   1e-42
gi|15805662|ref|NP_294358.1| 6-phosphofructokinase [Deinococcus ...   177   1e-42
gi|37528589|ref|NP_931934.1| 6-phosphofructokinase isozyme I (ph...   176   2e-42
gi|33151683|ref|NP_873036.1| phosphofructokinase [Haemophilus du...   176   3e-42
gi|29375624|ref|NP_814778.1| 6-phosphofructokinase [Enterococcus...   176   3e-42
gi|15900779|ref|NP_345383.1| 6-phosphofructokinase [Streptococcu...   175   5e-42
gi|23002843|ref|ZP_00046515.1| COG0205: 6-phosphofructokinase [L...   175   5e-42
gi|42519005|ref|NP_964935.1| 6-phosphofructokinase [Lactobacillu...   174   9e-42
gi|22537101|ref|NP_687952.1| 6-phosphofructokinase [Streptococcu...   174   9e-42
gi|46909431|gb|AAT06233.1| phosphofructokinase [Priapulus caudatus]   173   2e-41
gi|15902840|ref|NP_358390.1| 6-phosphofructokinase I [Streptococ...   173   2e-41
gi|547755|sp|P80019|K6PF_LACDE 6-phosphofructokinase (Phosphofru...   172   3e-41
gi|47094215|ref|ZP_00231928.1| 6-phosphofructokinase [Listeria m...   171   7e-41
gi|42366|emb|CAA26356.1| pfkA [Escherichia coli]                      171   7e-41
gi|21672572|ref|NP_660639.1| 6-phosphofructokinase [Buchnera aph...   171   7e-41
gi|37935712|gb|AAP72038.1| phosphofructokinase [Lactobacillus ca...   170   1e-40
gi|15616915|ref|NP_240128.1| 6-phosphofructokinase isozyme I [Bu...   170   1e-40
gi|46909415|gb|AAT06225.1| phosphofructokinase [Obelia sp. KJP-2...   170   2e-40
gi|33520038|ref|NP_878870.1| 6-phosphofructokinase [Candidatus B...   167   1e-39
gi|46909433|gb|AAT06234.1| phosphofructokinase [Monosiga brevico...   166   2e-39
gi|48833695|ref|ZP_00290712.1| COG0205: 6-phosphofructokinase [M...   166   2e-39
gi|24379619|ref|NP_721574.1| 6-phosphofructokinase [Streptococcu...   164   7e-39
gi|25027904|ref|NP_737958.1| putative 6-phosphofructokinase [Cor...   164   7e-39
gi|27904778|ref|NP_777904.1| 6-phosphofructokinase [Buchnera aph...   164   9e-39
gi|42560808|ref|NP_975259.1| 6-phosphofructokinase [Mycoplasma m...   164   1e-38
gi|34557414|ref|NP_907229.1| PFK PROTEIN [Wolinella succinogenes...   163   2e-38
gi|50364990|ref|YP_053415.1| 6-phosphofructokinase [Mesoplasma f...   162   3e-38
gi|19746206|ref|NP_607342.1| putative 6-phosphofructokinase [Str...   162   4e-38
gi|21910449|ref|NP_664717.1| putative 6-phosphofructokinase [Str...   162   4e-38
gi|15606791|ref|NP_214171.1| phosphofructokinase [Aquifex aeolic...   161   6e-38
gi|15675236|ref|NP_269410.1| putative 6-phosphofructokinase [Str...   160   1e-37
gi|13629190|sp|Q9L9E3|K6PF_STRTR 6-phosphofructokinase (Phosphof...   159   3e-37
gi|28378549|ref|NP_785441.1| 6-phosphofructokinase [Lactobacillu...   157   8e-37
gi|41325473|emb|CAF19953.1| 6-PHOSPHOFRUCTOKINASE [Corynebacteri...   156   2e-36
gi|1346354|sp|P20275|K6PF_SPICI 6-phosphofructokinase (Phosphofr...   156   2e-36
gi|19552471|ref|NP_600473.1| 6-phosphofructokinase [Corynebacter...   156   2e-36
gi|38233682|ref|NP_939449.1| 6-phosphofructokinase I [Corynebact...   156   2e-36
gi|29833665|ref|NP_828299.1| putative 6-phosphofructokinase [Str...   154   9e-36
gi|11259230|pir||T45407 phosphofructokinase [imported] - Mycobac...   153   2e-35
gi|21219724|ref|NP_625503.1| 6-phosphofructokinase [Streptomyces...   152   3e-35
gi|49236330|ref|ZP_00330390.1| COG0205: 6-phosphofructokinase [M...   152   3e-35
gi|18310167|ref|NP_562101.1| 6-phosphofructokinase [Clostridium ...   152   5e-35
gi|39938767|ref|NP_950533.1| 6-phosphofructokinase [Onion yellow...   151   6e-35
gi|15827907|ref|NP_302170.1| 6-phosphofructokinase [Mycobacteriu...   151   8e-35
gi|39996803|ref|NP_952754.1| 6-phosphofructokinase [Geobacter su...   150   2e-34
gi|29653691|ref|NP_819383.1| 6-phosphofructokinase [Coxiella bur...   149   2e-34
gi|48845947|ref|ZP_00300216.1| COG0205: 6-phosphofructokinase [G...   149   2e-34
gi|15610147|ref|NP_217526.1| pfkA [Mycobacterium tuberculosis H3...   149   3e-34
gi|41409142|ref|NP_961978.1| PfkA [Mycobacterium avium subsp. pa...   149   3e-34
gi|47459155|ref|YP_016017.1| 6-phosphofructokinase [Mycoplasma m...   148   5e-34
gi|21220597|ref|NP_626376.1| 6-phosphofructokinase [Streptomyces...   148   5e-34
gi|21223785|ref|NP_629564.1| 6-phosphofructokinase [Streptomyces...   147   1e-33
gi|30923152|sp|Q59126|PFP_AMYME Pyrophosphate--fructose 6-phosph...   147   1e-33
gi|50876798|emb|CAG36638.1| probable 6-phosphofructokinase 1 [De...   147   1e-33
gi|1173551|gb|AAB01683.1| pyrophosphate-dependent phosphofructok...   147   1e-33
gi|29348765|ref|NP_812268.1| 6-phosphofructokinase [Bacteroides ...   145   4e-33
gi|22973383|ref|ZP_00020082.1| hypothetical protein [Chloroflexu...   145   4e-33
gi|29832625|ref|NP_827259.1| putative 6-phosphofructokinase [Str...   145   4e-33
gi|30913142|sp|Q9AGC0|PFP_AMYMD Pyrophosphate--fructose 6-phosph...   143   2e-32
gi|31544684|ref|NP_853262.1| PfkA [Mycoplasma gallisepticum R] >...   142   5e-32
gi|29829364|ref|NP_823998.1| putative 6-phosphofructokinase [Str...   140   1e-31
gi|48836791|ref|ZP_00293787.1| COG0205: 6-phosphofructokinase [T...   140   1e-31
gi|30913145|sp|Q9KH71|PFP_DICTH Pyrophosphate--fructose 6-phosph...   139   4e-31
gi|45547787|ref|ZP_00187828.1| COG0205: 6-phosphofructokinase [R...   138   5e-31
gi|48867561|ref|ZP_00321048.1| COG0205: 6-phosphofructokinase [H...   136   2e-30
gi|16329437|ref|NP_440165.1| phosphofructokinase [Synechocystis ...   135   6e-30
gi|15829072|ref|NP_326432.1| 6-PHOSPHOFRUCTOKINASE (PHOSPHOFRUCT...   134   8e-30
gi|24211882|sp|Q8YKG3|K6P1_ANASP 6-phosphofructokinase 1 (Phosph...   133   2e-29
gi|20799496|gb|AAM28521.1| phosphofructokinase liver isoform [Ov...   131   6e-29
gi|6683553|dbj|BAA89245.1| similar to Lactococcus lactis 6-phosp...   130   1e-28
gi|48765145|ref|ZP_00269696.1| COG0205: 6-phosphofructokinase [R...   130   2e-28
gi|23130116|ref|ZP_00111935.1| COG0205: 6-phosphofructokinase [N...   129   2e-28
gi|45511778|ref|ZP_00163345.1| COG0205: 6-phosphofructokinase [S...   128   5e-28
gi|22298859|ref|NP_682106.1| 6-phosphofructokinase [Thermosynech...   128   5e-28
gi|5690378|gb|AAD47060.1| Pfk1 [Myxococcus xanthus]                   128   7e-28
gi|47196917|emb|CAF87476.1| unnamed protein product [Tetraodon n...   125   3e-27
gi|13508041|ref|NP_109990.1| 6-phosphofructokinase [Mycoplasma p...   125   5e-27
gi|3087896|emb|CAA74985.1| alternative product name: pyrophospha...   122   5e-26
gi|26554044|ref|NP_757978.1| 6-phosphofructokinase [Mycoplasma p...   121   7e-26
gi|2344771|dbj|BAA21892.1| phosphofructokinase-M [Mus musculus]       120   1e-25
gi|17229405|ref|NP_485953.1| 6-phosphofructokinase [Nostoc sp. P...   119   4e-25
gi|46365624|ref|ZP_00228080.1| COG0205: 6-phosphofructokinase [K...   116   3e-24
gi|50841581|ref|YP_054808.1| 6-phosphofructokinase 2 [Propioniba...   116   3e-24
gi|45506547|ref|ZP_00158900.1| COG0205: 6-phosphofructokinase [A...   116   3e-24
gi|26338696|dbj|BAC33019.1| unnamed protein product [Mus musculus]    114   8e-24
gi|7331123|gb|AAF60284.1| phosphofructokinase [Ovis aries]            114   1e-23
gi|12045069|ref|NP_072880.1| 6-phosphofructokinase (pfk) [Mycopl...   114   1e-23
gi|16331971|ref|NP_442699.1| phosphofructokinase [Synechocystis ...   106   3e-21
gi|609335|gb|AAA70114.1| PfkA                                          98   1e-18
gi|50796218|ref|XP_428172.1| PREDICTED: similar to guanylate bin...    94   1e-17
gi|23111717|ref|ZP_00097310.1| COG0205: 6-phosphofructokinase [D...    92   4e-17
gi|34909350|ref|NP_916022.1| putative pyrophosphate--fructose-6-...    91   1e-16
gi|18416717|ref|NP_567742.1| phosphofructokinase family protein ...    91   2e-16
gi|1084992|pir||S49458 diphosphate-fructose-6-phosphate 1-phosph...    89   4e-16
gi|21593599|gb|AAM65566.1| putative pyrophosphate--fructose-6-ph...    89   4e-16
gi|529009|gb|AAA92671.1| PPi-dependent phosphofructo-1-kinase >g...    89   4e-16
gi|18423885|ref|NP_568842.1| phosphofructokinase family protein ...    89   6e-16
gi|7488164|pir||T06011 probable diphosphate-fructose-6-phosphate...    88   8e-16
gi|15233959|ref|NP_195010.1| phosphofructokinase family protein ...    88   1e-15
gi|47777436|gb|AAT38069.1| putative pyrophosphate-fructose-6-pho...    87   1e-15
gi|15233495|ref|NP_194651.1| phosphofructokinase family protein ...    87   1e-15
gi|22136018|gb|AAM91591.1| pyrophosphate-dependent phosphofructo...    87   1e-15
gi|46363234|ref|ZP_00226006.1| COG0205: 6-phosphofructokinase [K...    87   2e-15
gi|10176767|dbj|BAB09881.1| pyrophosphate-dependent phosphofruct...    87   2e-15
gi|2583148|gb|AAC47836.1| 6-phospho-1-fructokinase [Trypanosoma ...    86   3e-15
gi|34906422|ref|NP_914558.1| putative pyrophosphate-dependent ph...    86   4e-15
gi|22328001|ref|NP_200966.2| phosphofructokinase family protein ...    85   9e-15
gi|24217172|ref|NP_714655.1| pyrophosphate--fructose 6-phosphate...    83   3e-14
gi|17432243|gb|AAL39011.1| phosphofructokinase [Amycolatopsis me...    82   6e-14
gi|50121280|ref|YP_050447.1| putative 6-phosphofructokinase isoz...    80   2e-13
gi|13641358|gb|AAK31633.1| phosphofructokinase [Leishmania donov...    79   4e-13
gi|4704295|emb|CAB41686.1| 6-phosphofructokinase [Piromyces sp. E2]    78   1e-12
gi|27377961|ref|NP_769490.1| bll2850 [Bradyrhizobium japonicum U...    77   2e-12
gi|15595072|ref|NP_212861.1| pyrophosphate--fructose 6-phosphate...    76   3e-12
gi|21673089|ref|NP_661154.1| phosphofructokinase [Chlorobium tep...    76   4e-12
gi|30681728|ref|NP_850025.1| phosphofructokinase family protein ...    76   4e-12
gi|24473732|gb|AAL18001.1| phosphofructokinase [Fundulus heteroc...    75   7e-12
gi|25287426|pir||B84613 hypothetical protein At2g22480 [imported...    73   4e-11
gi|1078995|pir||A61621 6-phosphofructokinase (EC 2.7.1.11), larv...    72   5e-11
gi|15643058|ref|NP_228101.1| 6-phosphofructokinase, pyrophosphat...    72   8e-11
gi|33322945|gb|AAQ07209.1| 6-phosphofructokinase [Lactobacillus ...    71   1e-10
gi|46580466|ref|YP_011274.1| 6-phosphofructokinase [Desulfovibri...    71   1e-10
gi|18129339|emb|CAC84571.1| 6-phospho-1-fructokinase [Trypanopla...    71   1e-10
gi|32474899|ref|NP_867893.1| 6-phosphofructokinase, pyrophosphat...    70   2e-10
gi|23474907|ref|ZP_00130198.1| COG0205: 6-phosphofructokinase [D...    70   3e-10
gi|511231|gb|AAA85791.1| pyrophosphate-dependent phosphofructo-1...    69   7e-10
gi|13357743|ref|NP_078017.1| 6-phosphofructokinase [Ureaplasma p...    67   1e-09
gi|33867640|gb|AAQ55175.1| phosphofructokinase [Monosiga ovata]        67   3e-09
gi|2117772|pir||S54978 6-phosphofructokinase (EC 2.7.1.11), pyro...    66   3e-09
gi|48860634|ref|ZP_00314546.1| COG0205: 6-phosphofructokinase [M...    66   4e-09
gi|3005083|gb|AAD13344.1| pyrophosphate-dependent fructose 6-pho...    65   7e-09
gi|21674421|ref|NP_662486.1| phosphofructokinase [Chlorobium tep...    65   1e-08
gi|1881848|gb|AAB49534.1| phosphofructokinase [Cottocomephorus g...    64   1e-08
gi|2981237|gb|AAD13345.1| PPi-dependent fructose 6-phosphate 1-p...    64   2e-08
gi|50251540|dbj|BAD28914.1| putative phosphofructokinase [Oryza ...    63   3e-08
gi|2981239|gb|AAD13346.1| PPi-dependent fructose 6-phosphate 1-p...    62   8e-08
gi|2688822|gb|AAB88875.1| pyrophosphate-dependent phosphofructo-...    61   1e-07
gi|23113648|ref|ZP_00099007.1| COG0205: 6-phosphofructokinase [D...    61   1e-07
gi|42408655|dbj|BAD09875.1| putative diphosphate-fructose-6-phos...    61   1e-07
gi|11528427|gb|AAG37271.1| pyrophosphate-dependent phosphofructo...    61   1e-07
gi|48858111|ref|ZP_00312077.1| COG0205: 6-phosphofructokinase [C...    60   2e-07
gi|42525583|ref|NP_970681.1| phosphofructokinase [Treponema dent...    60   2e-07
gi|37534192|ref|NP_921398.1| putative pyrophosphate--fructose-6-...    58   9e-07
gi|47226319|emb|CAG09287.1| unnamed protein product [Tetraodon n...    58   1e-06
gi|15639102|ref|NP_218548.1| pyrophosphate--fructose 6-phosphate...    58   1e-06
gi|34497200|ref|NP_901415.1| 6-phosphofructokinase [Chromobacter...    57   2e-06
gi|50725858|dbj|BAD33387.1| phosphofructokinase-like [Oryza sati...    57   3e-06
gi|45545900|ref|ZP_00186015.1| COG0205: 6-phosphofructokinase [R...    56   3e-06
gi|29840368|ref|NP_829474.1| pyrophosphate--fructose 6-phosphate...    55   6e-06
gi|47573619|ref|ZP_00243657.1| COG0205: 6-phosphofructokinase [R...    55   1e-05
gi|23111718|ref|ZP_00097311.1| COG0205: 6-phosphofructokinase [D...    55   1e-05
gi|15604927|ref|NP_219711.1| Fructose-6-P Phosphotransferase [Ch...    54   1e-05
gi|2911673|emb|CAA11968.1| pyrophosphate-fructose 6-phosphate 1-...    54   1e-05
gi|7447686|pir||D70102 pyrophosphate-fructose 6-phosphate 1-phos...    54   1e-05
gi|15594366|ref|NP_212154.1| pyrophosphate--fructose 6-phosphate...    54   1e-05
gi|41723516|ref|ZP_00150443.1| COG0205: 6-phosphofructokinase [D...    54   1e-05
gi|15238818|ref|NP_199592.1| phosphofructokinase family protein ...    54   2e-05
gi|15639531|ref|NP_218981.1| pyrophosphate--fructose 6-phosphate...    54   2e-05
gi|2344773|dbj|BAA21893.1| phosphofructokinase-M (connecting pep...    54   2e-05
gi|18310449|ref|NP_562383.1| 6-phosphofructokinase [Clostridium ...    53   3e-05
gi|23119763|ref|ZP_00102706.1| COG0205: 6-phosphofructokinase [D...    53   4e-05
gi|7862073|gb|AAF70463.1| PPi-phosphofructokinase [Mastigamoeba ...    52   5e-05
gi|47225150|emb|CAF98777.1| unnamed protein product [Tetraodon n...    52   5e-05
gi|46228247|gb|EAK89146.1| pyrophosphate-dependent 6-phosphofruc...    52   6e-05
gi|31873441|emb|CAD97816.1| hypothetical protein [Homo sapiens]        52   8e-05
gi|15835097|ref|NP_296856.1| pyrophosphate--fructose 6-phosphate...    51   1e-04
gi|23016100|ref|ZP_00055860.1| COG0205: 6-phosphofructokinase [M...    51   1e-04
gi|15618132|ref|NP_224417.1| Fructose-6-P Phosphotransferase [Ch...    51   1e-04
gi|886937|emb|CAA61193.1| ORF194 [Saccharomyces cerevisiae]            51   1e-04
gi|30249886|ref|NP_841956.1| Phosphofructokinase [Nitrosomonas e...    51   1e-04
gi|15836879|ref|NP_297567.1| 6-phosphofructokinase [Xylella fast...    51   1e-04
gi|32476511|ref|NP_869505.1| PPi-phosphofructokinase [Pirellula ...    50   2e-04
gi|49235891|ref|ZP_00329955.1| COG0205: 6-phosphofructokinase [M...    50   2e-04
gi|21244163|ref|NP_643745.1| 6-phosphofructokinase [Xanthomonas ...    50   2e-04
gi|100462|pir||B36094 diphosphate-fructose-6-phosphate 1-phospho...    50   3e-04
gi|2507174|sp|P21343|PFPB_SOLTU Pyrophosphate--fructose 6-phosph...    50   3e-04
gi|29345717|ref|NP_809220.1| phosphofructokinase [Bacteroides th...    49   4e-04
gi|38606536|emb|CAE75963.1| OSJNBa0016O02.24 [Oryza sativa (japo...    49   4e-04
gi|21232721|ref|NP_638638.1| 6-phosphofructokinase [Xanthomonas ...    49   4e-04
gi|15835095|ref|NP_296854.1| pyrophosphate--fructose 6-phosphate...    49   5e-04
gi|50842568|ref|YP_055795.1| pyrophosphate--fructose 6-phosphate...    49   5e-04
gi|28198149|ref|NP_778463.1| 6-phosphofructokinase [Xylella fast...    49   5e-04
gi|22997632|ref|ZP_00041860.1| COG0205: 6-phosphofructokinase [X...    49   7e-04
gi|15604925|ref|NP_219709.1| Fructose-6-P Phosphotransferase [Ch...    49   7e-04
gi|22995856|ref|ZP_00040157.1| COG0205: 6-phosphofructokinase [X...    49   7e-04
gi|15618084|ref|NP_224368.1| Fructose-6-P Phosphotransferase [Ch...    48   0.001
gi|15835695|ref|NP_300219.1| fructose-6-P phosphotransferase [Ch...    48   0.001
gi|30679628|ref|NP_192313.2| pyrophosphate--fructose-6-phosphate...    47   0.002
gi|2317746|gb|AAC04465.1| PPi-dependent phosphofructokinase [Ent...    47   0.002
gi|1665840|emb|CAA70350.1| pyrophosphate--fructose 6-phosphate 1...    47   0.002
gi|29840366|ref|NP_829472.1| pyrophosphate--fructose 6-phosphate...    47   0.002
gi|38047691|gb|AAR09748.1| similar to Drosophila melanogaster Pf...    47   0.002
gi|46227861|gb|EAK88781.1| pyrophosphate-dependent phosphofructo...    47   0.003
gi|42527058|ref|NP_972156.1| phosphofructokinase, pyrophosphate-...    46   0.004
gi|23012251|ref|ZP_00052382.1| COG0205: 6-phosphofructokinase [M...    46   0.004
gi|3041862|gb|AAC12961.1| phosphofructokinase I [Bacillus subtilis]    46   0.004
gi|15221156|ref|NP_172664.1| pyrophosphate--fructose-6-phosphate...    46   0.005
gi|1346693|sp|P29495|PFP_PROFR Pyrophosphate--fructose 6-phospha...    46   0.005
gi|15965943|ref|NP_386296.1| PROBABLE PYROPHOSPHATE--FRUCTOSE 6-...    45   0.006
gi|48763994|ref|ZP_00268547.1| COG0205: 6-phosphofructokinase [R...    45   0.008
gi|29654574|ref|NP_820266.1| phosphofructokinase, putative [Coxi...    45   0.010
gi|16304156|gb|AAL16943.1| putative pyrophosphate-dependent phos...    45   0.010
gi|23613673|ref|NP_704694.1| 6-phosphofructokinase, putative [Pl...    44   0.013
gi|2499489|sp|Q41141|PFPB_RICCO Pyrophosphate--fructose 6-phosph...    44   0.017
gi|34540025|ref|NP_904504.1| phosphofructokinase [Porphyromonas ...    44   0.023
gi|7447689|pir||T01470 diphosphate-fructose-6-phosphate 1-phosph...    44   0.023
gi|23485880|gb|EAA20618.1| pyrophosphate-dependent phosphofructo...    44   0.023
gi|17935999|ref|NP_532789.1| pyrophosphate--fructose-6-phosphate...    43   0.039
gi|15889397|ref|NP_355078.1| AGR_C_3836p [Agrobacterium tumefaci...    43   0.039
gi|48831842|ref|ZP_00288892.1| COG0205: 6-phosphofructokinase [M...    43   0.039
gi|25314952|pir||A86255 hypothetical protein [imported] - Arabid...    43   0.039
gi|3790100|gb|AAC67586.1| pyrophosphate-dependent phosphofructok...    42   0.051
gi|7416872|gb|AAF62345.1| muscle type phosphofructokinase [Equus...    42   0.051
gi|13474191|ref|NP_105759.1| 6-phosphofructokinase (EC 2.7.1.11)...    42   0.066
gi|553610|gb|AAA60069.1| phosphofructokinase [Homo sapiens]            42   0.066
gi|23477969|gb|EAA15183.1| hypothetical protein [Plasmodium yoel...    41   0.15
gi|46446514|ref|YP_007879.1| putative 6-phosphofructokinase 1 [P...    41   0.15
gi|3790102|gb|AAC67587.1| pyrophosphate-dependent phosphofructok...    40   0.33
gi|2499488|sp|Q41140|PFPA_RICCO Pyrophosphate--fructose 6-phosph...    39   0.43
gi|4098526|gb|AAD00300.1| phosphofructokinase [Prochlorothrix ho...    39   0.43
gi|47197208|emb|CAF87544.1| unnamed protein product [Tetraodon n...    39   0.43
gi|18698305|emb|CAD23127.1| ATP:D-fructose 6-phosphate 1-phospho...    39   0.43
gi|20260780|ref|NP_620099.1| putative [Powassan virus] >gnl|BL_O...    39   0.73
gi|27596769|ref|NP_775520.1| non-structural protein NS3 [Powassa...    39   0.73
gi|48780724|ref|ZP_00277410.1| COG0129: Dihydroxyacid dehydratas...    37   1.6
gi|1078721|pir||S52081 diphosphate-fructose-6-phosphate 1-phosph...    37   1.6
gi|17017953|ref|NP_476520.1| polyprotein [Deer tick virus] >gnl|...    37   2.8
gi|27673961|ref|NP_775637.1| non-structural protein NS3 [Deer ti...    37   2.8
gi|42733686|gb|AAS38630.1| similar to Dictyostelium discoideum (...    36   3.6
gi|32038565|ref|ZP_00136837.1| COG0477: Permeases of the major f...    36   3.6
gi|15598661|ref|NP_252155.1| conserved hypothetical protein [Pse...    36   3.6
gi|24639109|ref|NP_569923.2| CG14782-PA [Drosophila melanogaster...    36   4.8
gi|45916732|ref|ZP_00195738.2| COG0205: 6-phosphofructokinase [M...    36   4.8
gi|23119053|ref|ZP_00102302.1| COG2720: Uncharacterized vancomyc...    35   6.2
gi|6435840|gb|AAF08544.1| SPLF2 glycoprotein [Cercopithecine her...    35   6.2
gi|42525809|ref|NP_970907.1| MATE efflux family protein [Trepone...    35   8.1
gi|24373032|ref|NP_717074.1| type I restriction-modification sys...    35   8.1
gi|39595968|emb|CAE67471.1| Hypothetical protein CBG12974 [Caeno...    35   8.1


>gi|25147587|ref|NP_741739.1| phosphofructokinase (XD563)
            [Caenorhabditis elegans]
 gi|16604234|gb|AAL27269.1| Hypothetical protein Y71H10A.1b
            [Caenorhabditis elegans]
          Length = 781

 Score = 1520 bits (3935), Expect = 0.0
 Identities = 769/781 (98%), Positives = 769/781 (98%)
 Frame = +1

Query: 1    MDADASTITPEELDFIRQRALRRFDSIVPTAGREGTEIASDIFKGRTLAIYTSGGDSQGM 180
            MDADASTITPEELDFIRQRALRRFDSIVPTAGREGTEIASDIFKGRTLAIYTSGGDSQGM
Sbjct: 1    MDADASTITPEELDFIRQRALRRFDSIVPTAGREGTEIASDIFKGRTLAIYTSGGDSQGM 60

Query: 181  NSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVSDIIQQGGTIIGSARSS 360
            NSAVRSITRMAIYCGCKVYL            DFIKEATWNTVSDIIQQGGTIIGSARSS
Sbjct: 61   NSAVRSITRMAIYCGCKVYLIYEGYEGMIEGGDFIKEATWNTVSDIIQQGGTIIGSARSS 120

Query: 361  EFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAAA 540
            EFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAAA
Sbjct: 121  EFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAAA 180

Query: 541  KKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGR 720
            KKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGR
Sbjct: 181  KKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGR 240

Query: 721  HCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRD 900
            HCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRD
Sbjct: 241  HCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRD 300

Query: 901  GKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEE 1080
            GKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEE
Sbjct: 301  GKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEE 360

Query: 1081 SEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLLTK 1260
            SEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLLTK
Sbjct: 361  SEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLLTK 420

Query: 1261 MRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANG 1440
            MRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANG
Sbjct: 421  MRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANG 480

Query: 1441 SFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHNIQALLLVGGFEAYHST 1620
            SFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHNIQALLLVGGFEAYHST
Sbjct: 481  SFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHNIQALLLVGGFEAYHST 540

Query: 1621 IILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKR 1800
            IILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKR
Sbjct: 541  IILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKR 600

Query: 1801 RVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLV 1980
            RVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLV
Sbjct: 601  RVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLV 660

Query: 1981 VRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALE 2160
            VRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALE
Sbjct: 661  VRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALE 720

Query: 2161 FLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKKETDFEHRLPSEQWLVD 2340
            FLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKKETDFEHRLPSEQWLVD
Sbjct: 721  FLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKKETDFEHRLPSEQWLVD 780

Query: 2341 K 2343
            K
Sbjct: 781  K 781


>gi|25147584|ref|NP_741738.1| phosphofructokinase (89.7 kD) (XD563)
            [Caenorhabditis elegans]
 gi|14574481|gb|AAC67416.2| Hypothetical protein Y71H10A.1a
            [Caenorhabditis elegans]
          Length = 814

 Score = 1513 bits (3916), Expect = 0.0
 Identities = 765/777 (98%), Positives = 765/777 (98%)
 Frame = +1

Query: 1    MDADASTITPEELDFIRQRALRRFDSIVPTAGREGTEIASDIFKGRTLAIYTSGGDSQGM 180
            MDADASTITPEELDFIRQRALRRFDSIVPTAGREGTEIASDIFKGRTLAIYTSGGDSQGM
Sbjct: 1    MDADASTITPEELDFIRQRALRRFDSIVPTAGREGTEIASDIFKGRTLAIYTSGGDSQGM 60

Query: 181  NSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVSDIIQQGGTIIGSARSS 360
            NSAVRSITRMAIYCGCKVYL            DFIKEATWNTVSDIIQQGGTIIGSARSS
Sbjct: 61   NSAVRSITRMAIYCGCKVYLIYEGYEGMIEGGDFIKEATWNTVSDIIQQGGTIIGSARSS 120

Query: 361  EFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAAA 540
            EFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAAA
Sbjct: 121  EFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAAA 180

Query: 541  KKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGR 720
            KKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGR
Sbjct: 181  KKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGR 240

Query: 721  HCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRD 900
            HCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRD
Sbjct: 241  HCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRD 300

Query: 901  GKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEE 1080
            GKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEE
Sbjct: 301  GKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEE 360

Query: 1081 SEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLLTK 1260
            SEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLLTK
Sbjct: 361  SEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLLTK 420

Query: 1261 MRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANG 1440
            MRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANG
Sbjct: 421  MRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANG 480

Query: 1441 SFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHNIQALLLVGGFEAYHST 1620
            SFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHNIQALLLVGGFEAYHST
Sbjct: 481  SFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHNIQALLLVGGFEAYHST 540

Query: 1621 IILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKR 1800
            IILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKR
Sbjct: 541  IILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKR 600

Query: 1801 RVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLV 1980
            RVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLV
Sbjct: 601  RVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLV 660

Query: 1981 VRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALE 2160
            VRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALE
Sbjct: 661  VRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALE 720

Query: 2161 FLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKKETDFEHRLPSEQW 2331
            FLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKKETDFEHRLPSEQW
Sbjct: 721  FLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKKETDFEHRLPSEQW 777


>gi|7510438|pir||T33481 hypothetical protein Y71H10A.1 -
            Caenorhabditis elegans
          Length = 828

 Score = 1503 bits (3891), Expect = 0.0
 Identities = 765/791 (96%), Positives = 765/791 (96%), Gaps = 14/791 (1%)
 Frame = +1

Query: 1    MDADASTITPEELDFIRQRALRRFDSIVPTAGREGTEIASDIFKGRTLAIYTSGGDSQGM 180
            MDADASTITPEELDFIRQRALRRFDSIVPTAGREGTEIASDIFKGRTLAIYTSGGDSQGM
Sbjct: 1    MDADASTITPEELDFIRQRALRRFDSIVPTAGREGTEIASDIFKGRTLAIYTSGGDSQGM 60

Query: 181  NSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVSDIIQQGGTIIGSARSS 360
            NSAVRSITRMAIYCGCKVYL            DFIKEATWNTVSDIIQQGGTIIGSARSS
Sbjct: 61   NSAVRSITRMAIYCGCKVYLIYEGYEGMIEGGDFIKEATWNTVSDIIQQGGTIIGSARSS 120

Query: 361  EFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAAA 540
            EFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAAA
Sbjct: 121  EFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAAA 180

Query: 541  KKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGR 720
            KKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGR
Sbjct: 181  KKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGR 240

Query: 721  HCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRD 900
            HCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRD
Sbjct: 241  HCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRD 300

Query: 901  GKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTE- 1077
            GKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTE
Sbjct: 301  GKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEV 360

Query: 1078 -------------ESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGR 1218
                         ESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGR
Sbjct: 361  SGIFCEFFINGLNESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGR 420

Query: 1219 SFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQCT 1398
            SFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQCT
Sbjct: 421  SFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQCT 480

Query: 1399 VYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHNIQ 1578
            VYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHNIQ
Sbjct: 481  VYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHNIQ 540

Query: 1579 ALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQ 1758
            ALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQ
Sbjct: 541  ALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQ 600

Query: 1759 MIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDV 1938
            MIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDV
Sbjct: 601  MIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDV 660

Query: 1939 ILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPF 2118
            ILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPF
Sbjct: 661  ILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPF 720

Query: 2119 DRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKKET 2298
            DRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKKET
Sbjct: 721  DRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKKET 780

Query: 2299 DFEHRLPSEQW 2331
            DFEHRLPSEQW
Sbjct: 781  DFEHRLPSEQW 791


>gi|39591033|emb|CAE58813.1| Hypothetical protein CBG02020
            [Caenorhabditis briggsae]
          Length = 814

 Score = 1436 bits (3717), Expect = 0.0
 Identities = 723/777 (93%), Positives = 740/777 (95%)
 Frame = +1

Query: 1    MDADASTITPEELDFIRQRALRRFDSIVPTAGREGTEIASDIFKGRTLAIYTSGGDSQGM 180
            M  D S I+PEEL+ I QR LRRFDSIVPT+GREG EI+SDIFKGRTLAIYTSGGDSQGM
Sbjct: 1    MAEDNSMISPEELELIHQRTLRRFDSIVPTSGREGEEISSDIFKGRTLAIYTSGGDSQGM 60

Query: 181  NSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVSDIIQQGGTIIGSARSS 360
            NSAVRSITRMAIYCGCKVYL            DFIKEATWNTVSDIIQQGGTIIGSARSS
Sbjct: 61   NSAVRSITRMAIYCGCKVYLIYEGYEGMIEGGDFIKEATWNTVSDIIQQGGTIIGSARSS 120

Query: 361  EFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAAA 540
            EFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELV+  RVT A A
Sbjct: 121  EFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVRTDRVTPAMA 180

Query: 541  KKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGR 720
            KKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGR
Sbjct: 181  KKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGR 240

Query: 721  HCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRD 900
            HCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRD
Sbjct: 241  HCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRD 300

Query: 901  GKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEE 1080
            GK ITAEDVKTAVK KLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEE
Sbjct: 301  GKPITAEDVKTAVKNKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEE 360

Query: 1081 SEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLLTK 1260
            SEPCVISIDGNVMVRVPL KCVERTQMVQKAMADKDW TAV LRGRSFQRNL+TYKLLTK
Sbjct: 361  SEPCVISIDGNVMVRVPLTKCVERTQMVQKAMADKDWDTAVALRGRSFQRNLDTYKLLTK 420

Query: 1261 MRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANG 1440
            MRTVEKDNLS GHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQCTV+GIEDSFEGLANG
Sbjct: 421  MRTVEKDNLSGGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQCTVFGIEDSFEGLANG 480

Query: 1441 SFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHNIQALLLVGGFEAYHST 1620
            SFKQFKWSDVTNWAM GGSFLGTQKSLPT +TMP++A QLKKHNIQALLLVGGFEAYHST
Sbjct: 481  SFKQFKWSDVTNWAMYGGSFLGTQKSLPTAETMPKIAEQLKKHNIQALLLVGGFEAYHST 540

Query: 1621 IILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKR 1800
            I+LAE R+K+PEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKR
Sbjct: 541  ILLAEARDKFPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKR 600

Query: 1801 RVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLV 1980
            RVFIVETMGGYCGYLATLSA+SSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLV
Sbjct: 601  RVFIVETMGGYCGYLATLSAISSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLV 660

Query: 1981 VRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALE 2160
            VRNEWADKNLTTDFVQNLF+SEGKK FTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALE
Sbjct: 661  VRNEWADKNLTTDFVQNLFNSEGKKQFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALE 720

Query: 2161 FLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKKETDFEHRLPSEQW 2331
            FLLIQLKENLT DNKVIAK+ HTATLLGLKGRKVVFTPVQDLKKETDFEHRLP+EQW
Sbjct: 721  FLLIQLKENLTGDNKVIAKTPHTATLLGLKGRKVVFTPVQDLKKETDFEHRLPTEQW 777


>gi|38304370|gb|AAR16088.1| phosphofructokinase [Ascaris suum]
          Length = 812

 Score = 1087 bits (2812), Expect = 0.0
 Identities = 545/757 (71%), Positives = 626/757 (81%), Gaps = 2/757 (0%)
 Frame = +1

Query: 67   RFDSIVPTAGREGTEIASDIFKGRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXX 246
            R DSIVPTAG+EG+ I   ++KG+++A++TSGGD+ GMNSAVRS+ RM IY GC+VY
Sbjct: 24   RSDSIVPTAGKEGSIIVPHLYKGQSIAVFTSGGDAPGMNSAVRSVVRMGIYLGCRVYFIY 83

Query: 247  XXXXXXXXXXDFIKEATWNTVSDIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGR 426
                      D IKEA WN+VSDII++GGTIIG+ R  EFR REGRL+AA NLI   I
Sbjct: 84   EGYQGMVDGGDNIKEADWNSVSDIIRKGGTIIGTERGKEFREREGRLRAAENLIAHNITN 143

Query: 427  LVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGT 606
            LVCIGGDGSLTGAN FR EW  LV++L+   R+TA  A++   IQIVGLVGSIDNDFCGT
Sbjct: 144  LVCIGGDGSLTGANLFRQEWPGLVKDLLAAGRITAEKAQQCANIQIVGLVGSIDNDFCGT 203

Query: 607  DMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPE 786
            DMTIGTD+ALQRII +ID+V++TAQSHQR FVIEVMGRHCGYLA+VAALASEADFCFIPE
Sbjct: 204  DMTIGTDTALQRIIEAIDSVMSTAQSHQRCFVIEVMGRHCGYLAVVAALASEADFCFIPE 263

Query: 787  WPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTR 966
            WPAP +W DVLC KL  MR+EGQRLNIIIVAEGAIDR+GKAITAE V+  VK  L YDTR
Sbjct: 264  WPAPTDWPDVLCKKLQTMRAEGQRLNIIIVAEGAIDREGKAITAEIVRGVVKSTLHYDTR 323

Query: 967  VTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCV 1146
            VT+LGHVQRGG+PSAFDRLLGCRMGAEAV ALMEMT ESEPC++SIDGN+MVRVPL++CV
Sbjct: 324  VTVLGHVQRGGSPSAFDRLLGCRMGAEAVLALMEMTPESEPCLVSIDGNLMVRVPLMQCV 383

Query: 1147 ERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLLTKMR-TVEKDNLSEGHKFNVAVIN 1323
             RTQ VQKAM  +DW TAV LRGRSFQRNLETY+LLTK+    EKDNLS GHKFNVAVIN
Sbjct: 384  LRTQAVQKAMDARDWETAVKLRGRSFQRNLETYRLLTKLHIPKEKDNLSAGHKFNVAVIN 443

Query: 1324 VGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFL 1503
            VGAPAGGMNAAVRS+VRMA+YH C VYG+++SFEGLA G  K+  WSDV NW M+GGSFL
Sbjct: 444  VGAPAGGMNAAVRSFVRMAIYHHCRVYGVQNSFEGLARGDLKEMAWSDVNNWVMHGGSFL 503

Query: 1504 GTQKSLPTEKTMPQLAAQLKKHNIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIP 1683
            GTQK LP +K+MP++AA L K NI A+LLVGGFEAYHS ++L+  R  YP   IPMC+IP
Sbjct: 504  GTQKQLP-DKSMPEVAAVLAKFNIHAILLVGGFEAYHSCLLLSRARSIYPSLRIPMCIIP 562

Query: 1684 CTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSAL 1863
            CTISNN+PGT +SLGSDTA+NEIC MIDKIKQSATGTKRRVFIVETMGGYCGYLATLSAL
Sbjct: 563  CTISNNIPGTSLSLGSDTAVNEICHMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSAL 622

Query: 1864 SSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDS 2043
            +SGADNAYIFEE F V D+ +DV VI  KME G +RYL+VR E A++N TT+FV+ LF
Sbjct: 623  ASGADNAYIFEEKFGVLDILEDVKVITKKMEKGVQRYLIVRCELANRNYTTEFVKQLFAE 682

Query: 2044 EGKKNFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALEFLLIQLKENLTADNKVI-AKS 2220
            EGK  F+TR NVLGH QQGGSPTPFDRN+GTKLAARALE+L+ Q KE +     V  A +
Sbjct: 683  EGKGAFSTRTNVLGHAQQGGSPTPFDRNLGTKLAARALEYLVTQAKEAINLKTGVASATN 742

Query: 2221 AHTATLLGLKGRKVVFTPVQDLKKETDFEHRLPSEQW 2331
            A TATLLGL+GR+VVFTPV++L  ETDFEHRLP EQW
Sbjct: 743  ADTATLLGLRGRRVVFTPVEELALETDFEHRLPKEQW 779


>gi|3122304|sp|Q27665|K6PF_HAECO 6-phosphofructokinase
            (Phosphofructokinase) (Phosphohexokinase)
 gi|345391|pir||A45617 6-phosphofructokinase (EC 2.7.1.11) - nematode
            (Haemonchus contortus)
 gi|159185|gb|AAA29181.1| ADP:D-fructose-6-phosphate
            1-phosphotransferase
          Length = 789

 Score = 1083 bits (2800), Expect = 0.0
 Identities = 548/762 (71%), Positives = 631/762 (81%), Gaps = 2/762 (0%)
 Frame = +1

Query: 52   QRALRRFDSIVPTAGREGTEIASDIFKGRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCK 231
            +R +RR DSIVPTAGREG++I  +++KGR +A++TSGGDSQGMN AV S+ RM IY GCK
Sbjct: 4    KRNIRRLDSIVPTAGREGSDIQFNLYKGRGVAVFTSGGDSQGMNGAVHSVVRMGIYLGCK 63

Query: 232  VYLXXXXXXXXXXXXDFIKEATWNTVSDIIQQGGTIIGSARSSEFRTREGRLKAATNLIN 411
            V              D I EA+WN+ SDIIQ+GGTIIGSAR ++ R REGR+KAA NLI
Sbjct: 64   VCFINEGYQGMVDGGDNIVEASWNSGSDIIQKGGTIIGSARCTDLRQREGRMKAAYNLIE 123

Query: 412  RGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDN 591
            +GI  LV IGGDGSL GAN FR +W  LV+ELV  +++T  AAK  P IQIVGLVGSIDN
Sbjct: 124  KGITNLVVIGGDGSLIGANQFRKDWPGLVKELVDTKKITPEAAKSYPNIQIVGLVGSIDN 183

Query: 592  DFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMGRHCGYLALVAALASEADF 771
            DFCGTDMTIGTDSALQRII SIDAVVATAQSHQRAFV+EVMGRHCGYLALVAALA EADF
Sbjct: 184  DFCGTDMTIGTDSALQRIIESIDAVVATAQSHQRAFVVEVMGRHCGYLALVAALACEADF 243

Query: 772  CFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKL 951
            CFIPEWP P NWR++LC KL +MR+EGQRLNII+VAE   DRDG  I+++ VK  V + L
Sbjct: 244  CFIPEWPPPVNWREILCKKLQEMRAEGQRLNIIVVAEDD-DRDGTPISSDLVKDVVAKTL 302

Query: 952  KYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEESEPCVISIDGNVMVR-- 1125
            KYDTRVT+LGHVQRGG+PSAFDRLLGCRMGAEAV ALMEM EESEPCVISI   ++ R
Sbjct: 303  KYDTRVTVLGHVQRGGSPSAFDRLLGCRMGAEAVLALMEMNEESEPCVISI---MVTRWY 359

Query: 1126 VPLLKCVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLLTKMRTVEKDNLSEGHKF 1305
            VPL++CVERT+ VQKAM++KDW  AV LRGRSFQRNLETYKLLTK+RTVEKDNLS G  F
Sbjct: 360  VPLMQCVERTKAVQKAMSEKDWELAVKLRGRSFQRNLETYKLLTKLRTVEKDNLSGGQNF 419

Query: 1306 NVAVINVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAM 1485
            NVAV+NVGAPAGGMNAAVRS+VRMA+         EDSFEGLANG+FK+F+W DVTNW M
Sbjct: 420  NVAVMNVGAPAGGMNAAVRSFVRMAIVPSLYSLRYEDSFEGLANGAFKKFQWGDVTNWVM 479

Query: 1486 NGGSFLGTQKSLPTEKTMPQLAAQLKKHNIQALLLVGGFEAYHSTIILAENREKYPEFCI 1665
            +GGSFLGTQK LP EK +P +A QL+KHNIQALLLVGGFEAYHST+IL++NREKYPEFCI
Sbjct: 480  HGGSFLGTQKQLPNEKNVPLIAEQLRKHNIQALLLVGGFEAYHSTLILSKNREKYPEFCI 539

Query: 1666 PMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKRRVFIVETMGGYCGYL 1845
            P+CVIPCTISNNVPGT +SLGSDTAINEIC MIDKIKQSATGTKRRVFI+ETMGGYCGYL
Sbjct: 540  PLCVIPCTISNNVPGTSISLGSDTAINEICTMIDKIKQSATGTKRRVFIIETMGGYCGYL 599

Query: 1846 ATLSALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFV 2025
            ATLSAL+SGADNAYIFEE FTV ++S        KM  G +RYL+VRNE+A+KN TT+FV
Sbjct: 600  ATLSALASGADNAYIFEEKFTV-EISLRRGSHRCKMAQGVQRYLIVRNEYANKNFTTEFV 658

Query: 2026 QNLFDSEGKKNFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALEFLLIQLKENLTADNK 2205
            + LF  EGK  F+TR+N+LGH QQGGSPTPFDRNMGTKLAARALE+++ Q+KE++  +
Sbjct: 659  KQLFAEEGKGEFSTRINILGHAQQGGSPTPFDRNMGTKLAARALEYIITQIKESM-VNGV 717

Query: 2206 VIAKSAHTATLLGLKGRKVVFTPVQDLKKETDFEHRLPSEQW 2331
            V  KS   ATLLGL GR+VVFTPV++L  ETDF+ RLP +QW
Sbjct: 718  VSTKSPERATLLGLTGRRVVFTPVEELAAETDFDKRLPCDQW 759


>gi|28573326|ref|NP_724891.2| CG4001-PC [Drosophila melanogaster]
 gi|28380999|gb|AAM71065.2| CG4001-PC [Drosophila melanogaster]
          Length = 788

 Score =  894 bits (2311), Expect = 0.0
 Identities = 442/737 (59%), Positives = 562/737 (75%), Gaps = 3/737 (0%)
 Frame = +1

Query: 130  KGRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTV 309
            K + LA++TSGGDSQGMN+AVR+  RMAIY GCKVY             D I+EA W +V
Sbjct: 16   KDKGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGDCIQEANWASV 75

Query: 310  SDIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWT 489
            S II +GGTIIGSAR  +FR R+GRLKAA NLI RGI  LV IGGDGSLTGAN FR EW+
Sbjct: 76   SSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWS 135

Query: 490  DLVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVV 669
             L+ ELVKN+ +T    +K   + IVGLVGSIDNDFCGTDMTIGTD+AL RII +IDA+
Sbjct: 136  SLLDELVKNKTITTEQQEKFNVLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAIS 195

Query: 670  ATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSE 849
            +TA SHQR F++EVMGRHCGYLA+ AA+A+EADF FIPE P   NW+D +C KL Q RS
Sbjct: 196  STAYSHQRTFIMEVMGRHCGYLAISAAIATEADFMFIPEEPVSVNWKDEICVKLHQERSA 255

Query: 850  GQRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLG 1029
            GQRLNI+IVAEGA+DR+G  ITAEDVK  + E+LK+D R+T+LGHVQRGG PSAFDR+L
Sbjct: 256  GQRLNIVIVAEGAMDREGHPITAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILA 315

Query: 1030 CRMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVML 1209
            CRMGAEA  ALME T++S P VIS+DGN  VRVPL++CVERTQ V KAMA+K W  AV L
Sbjct: 316  CRMGAEATLALMEATKDSVPVVISLDGNQAVRVPLMECVERTQAVAKAMAEKRWADAVKL 375

Query: 1210 RGRSFQRNLETYKLLTKMRTVEKDNLSEG---HKFNVAVINVGAPAGGMNAAVRSYVRMA 1380
            RGRSF+RNLETYK+LT+++  +++  ++G     + +AV+++GAPA GMNAAVRS+VR A
Sbjct: 376  RGRSFERNLETYKMLTRLKPPKENFDADGKGIEGYRLAVMHIGAPACGMNAAVRSFVRNA 435

Query: 1381 LYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQL 1560
            +Y    VYGI D  EGL  G+ ++  WSDV+ W   GG++LGT+++LP E    ++AA+L
Sbjct: 436  IYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRTLP-EGKFKEIAARL 494

Query: 1561 KKHNIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTA 1740
            K+  IQ LL++GGFE+YH+   +A+ R+ YP+FCIP+ VIP TISNNVPGT  SLG DT
Sbjct: 495  KEFKIQGLLIIGGFESYHAAGQIADQRDNYPQFCIPIVVIPSTISNNVPGTEFSLGCDTG 554

Query: 1741 INEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDL 1920
            +NEI ++ D+I+QSA GTKRRVF++ETMGGYCGYLATL+ L+ GAD AYI+EE F+++DL
Sbjct: 555  LNEITEICDRIRQSAQGTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDL 614

Query: 1921 SDDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQG 2100
              DV  + SKM  G  R L++RNE A +N +TDF+  L+  EGK  FT R+N+LGH+QQG
Sbjct: 615  QQDVYHMASKMAEGVSRGLILRNEKASENYSTDFIYRLYSEEGKGLFTCRMNILGHMQQG 674

Query: 2101 GSPTPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQ 2280
            GSPTPFDRNMGTK+AA+ +++L  Q+K N+ A+  V  KS  TATLLG+  R+  F+P+
Sbjct: 675  GSPTPFDRNMGTKMAAKCVDWLAAQIKANIDANGVVNCKSPDTATLLGIVSRQYRFSPLV 734

Query: 2281 DLKKETDFEHRLPSEQW 2331
            DL  ET+F+ R+P +QW
Sbjct: 735  DLIAETNFDQRIPKKQW 751


>gi|17647809|ref|NP_523676.1| CG4001-PA [Drosophila melanogaster]
 gi|5052636|gb|AAD38648.1| BcDNA.GH12192 [Drosophila melanogaster]
 gi|7303792|gb|AAF58840.1| CG4001-PA [Drosophila melanogaster]
          Length = 950

 Score =  894 bits (2311), Expect = 0.0
 Identities = 443/738 (60%), Positives = 561/738 (75%), Gaps = 3/738 (0%)
 Frame = +1

Query: 127  FKGRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNT 306
            FK + LA++TSGGDSQGMN+AVR+  RMAIY GCKVY             D I+EA W +
Sbjct: 177  FKDKGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGDCIQEANWAS 236

Query: 307  VSDIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEW 486
            VS II +GGTIIGSAR  +FR R+GRLKAA NLI RGI  LV IGGDGSLTGAN FR EW
Sbjct: 237  VSSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEW 296

Query: 487  TDLVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAV 666
            + L+ ELVKN+ +T    +K   + IVGLVGSIDNDFCGTDMTIGTD+AL RII +IDA+
Sbjct: 297  SSLLDELVKNKTITTEQQEKFNVLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAI 356

Query: 667  VATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRS 846
             +TA SHQR F++EVMGRHCGYLALV  LA EADF FIPE P   +W D LC +L+Q RS
Sbjct: 357  SSTAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPEMPPKVDWPDRLCSQLAQERS 416

Query: 847  EGQRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLL 1026
             GQRLNI+IVAEGA+DR+G  ITAEDVK  + E+LK+D R+T+LGHVQRGG PSAFDR+L
Sbjct: 417  AGQRLNIVIVAEGAMDREGHPITAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRIL 476

Query: 1027 GCRMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVM 1206
             CRMGAEA  ALME T++S P VIS+DGN  VRVPL++CVERTQ V KAMA+K W  AV
Sbjct: 477  ACRMGAEATLALMEATKDSVPVVISLDGNQAVRVPLMECVERTQAVAKAMAEKRWADAVK 536

Query: 1207 LRGRSFQRNLETYKLLTKMRTVEKDNLSEG---HKFNVAVINVGAPAGGMNAAVRSYVRM 1377
            LRGRSF+RNLETYK+LT+++  +++  ++G     + +AV+++GAPA GMNAAVRS+VR
Sbjct: 537  LRGRSFERNLETYKMLTRLKPPKENFDADGKGIEGYRLAVMHIGAPACGMNAAVRSFVRN 596

Query: 1378 ALYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQ 1557
            A+Y    VYGI D  EGL  G+ ++  WSDV+ W   GG++LGT+++LP E    ++AA+
Sbjct: 597  AIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRTLP-EGKFKEIAAR 655

Query: 1558 LKKHNIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDT 1737
            LK+  IQ LL++GGFE+YH+   +A+ R+ YP+FCIP+ VIP TISNNVPGT  SLG DT
Sbjct: 656  LKEFKIQGLLIIGGFESYHAAGQIADQRDNYPQFCIPIVVIPSTISNNVPGTEFSLGCDT 715

Query: 1738 AINEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQD 1917
             +NEI ++ D+I+QSA GTKRRVF++ETMGGYCGYLATL+ L+ GAD AYI+EE F+++D
Sbjct: 716  GLNEITEICDRIRQSAQGTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKD 775

Query: 1918 LSDDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQ 2097
            L  DV  + SKM  G  R L++RNE A +N +TDF+  L+  EGK  FT R+N+LGH+QQ
Sbjct: 776  LQQDVYHMASKMAEGVSRGLILRNEKASENYSTDFIYRLYSEEGKGLFTCRMNILGHMQQ 835

Query: 2098 GGSPTPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPV 2277
            GGSPTPFDRNMGTK+AA+ +++L  Q+K N+ A+  V  KS  TATLLG+  R+  F+P+
Sbjct: 836  GGSPTPFDRNMGTKMAAKCVDWLAAQIKANIDANGVVNCKSPDTATLLGIVSRQYRFSPL 895

Query: 2278 QDLKKETDFEHRLPSEQW 2331
             DL  ET+F+ R+P +QW
Sbjct: 896  VDLIAETNFDQRIPKKQW 913


>gi|24652337|ref|NP_724890.1| CG4001-PB [Drosophila melanogaster]
 gi|7303793|gb|AAF58841.1| CG4001-PB [Drosophila melanogaster]
          Length = 788

 Score =  892 bits (2305), Expect = 0.0
 Identities = 442/737 (59%), Positives = 560/737 (75%), Gaps = 3/737 (0%)
 Frame = +1

Query: 130  KGRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTV 309
            K + LA++TSGGDSQGMN+AVR+  RMAIY GCKVY             D I+EA W +V
Sbjct: 16   KDKGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGDCIQEANWASV 75

Query: 310  SDIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWT 489
            S II +GGTIIGSAR  +FR R+GRLKAA NLI RGI  LV IGGDGSLTGAN FR EW+
Sbjct: 76   SSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWS 135

Query: 490  DLVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVV 669
             L+ ELVKN+ +T    +K   + IVGLVGSIDNDFCGTDMTIGTD+AL RII +IDA+
Sbjct: 136  SLLDELVKNKTITTEQQEKFNVLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAIS 195

Query: 670  ATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSE 849
            +TA SHQR F++EVMGRHCGYLALV  LA EADF FIPE P   +W D LC +L+Q RS
Sbjct: 196  STAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPEMPPKVDWPDRLCSQLAQERSA 255

Query: 850  GQRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLG 1029
            GQRLNI+IVAEGA+DR+G  ITAEDVK  + E+LK+D R+T+LGHVQRGG PSAFDR+L
Sbjct: 256  GQRLNIVIVAEGAMDREGHPITAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILA 315

Query: 1030 CRMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVML 1209
            CRMGAEA  ALME T++S P VIS+DGN  VRVPL++CVERTQ V KAMA+K W  AV L
Sbjct: 316  CRMGAEATLALMEATKDSVPVVISLDGNQAVRVPLMECVERTQAVAKAMAEKRWADAVKL 375

Query: 1210 RGRSFQRNLETYKLLTKMRTVEKDNLSEG---HKFNVAVINVGAPAGGMNAAVRSYVRMA 1380
            RGRSF+RNLETYK+LT+++  +++  ++G     + +AV+++GAPA GMNAAVRS+VR A
Sbjct: 376  RGRSFERNLETYKMLTRLKPPKENFDADGKGIEGYRLAVMHIGAPACGMNAAVRSFVRNA 435

Query: 1381 LYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQL 1560
            +Y    VYGI D  EGL  G+ ++  WSDV+ W   GG++LGT+++LP E    ++AA+L
Sbjct: 436  IYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRTLP-EGKFKEIAARL 494

Query: 1561 KKHNIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTA 1740
            K+  IQ LL++GGFE+YH+   +A+ R+ YP+FCIP+ VIP TISNNVPGT  SLG DT
Sbjct: 495  KEFKIQGLLIIGGFESYHAAGQIADQRDNYPQFCIPIVVIPSTISNNVPGTEFSLGCDTG 554

Query: 1741 INEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDL 1920
            +NEI ++ D+I+QSA GTKRRVF++ETMGGYCGYLATL+ L+ GAD AYI+EE F+++DL
Sbjct: 555  LNEITEICDRIRQSAQGTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDL 614

Query: 1921 SDDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQG 2100
              DV  + SKM  G  R L++RNE A +N +TDF+  L+  EGK  FT R+N+LGH+QQG
Sbjct: 615  QQDVYHMASKMAEGVSRGLILRNEKASENYSTDFIYRLYSEEGKGLFTCRMNILGHMQQG 674

Query: 2101 GSPTPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQ 2280
            GSPTPFDRNMGTK+AA+ +++L  Q+K N+ A+  V  KS  TATLLG+  R+  F+P+
Sbjct: 675  GSPTPFDRNMGTKMAAKCVDWLAAQIKANIDANGVVNCKSPDTATLLGIVSRQYRFSPLV 734

Query: 2281 DLKKETDFEHRLPSEQW 2331
            DL  ET+F+ R+P +QW
Sbjct: 735  DLIAETNFDQRIPKKQW 751


>gi|31198559|ref|XP_308227.1| ENSANGP00000021523 [Anopheles gambiae]
 gi|21291959|gb|EAA04104.1| ENSANGP00000021523 [Anopheles gambiae str.
            PEST]
          Length = 803

 Score =  882 bits (2278), Expect = 0.0
 Identities = 440/737 (59%), Positives = 554/737 (74%), Gaps = 3/737 (0%)
 Frame = +1

Query: 130  KGRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTV 309
            KG+ +A++TSGGDSQGMN+AVR++ RM IY GCKVY             D I EA W++V
Sbjct: 30   KGKGIAVFTSGGDSQGMNAAVRAVVRMGIYVGCKVYFIREGYQGMVDGGDNIVEANWSSV 89

Query: 310  SDIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWT 489
            S II +GGT+IGSAR  +FR R GRL+AA NL++RGI  LV IGGDGSLTGAN FR EW
Sbjct: 90   SSIIHRGGTVIGSARCKDFRERAGRLQAAHNLVSRGITNLVVIGGDGSLTGANLFRQEWG 149

Query: 490  DLVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVV 669
             L+ EL+ + R+T     K   + I G+VGSIDNDFCGTDMTIGTDSAL RII +IDA+V
Sbjct: 150  SLLDELLASNRITQDQRIKYKSLHIAGMVGSIDNDFCGTDMTIGTDSALHRIIEAIDAIV 209

Query: 670  ATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSE 849
            +TA SHQR F++EVMGRHCGYLA++AALASEAD+ FIPE P   NW + LC K+ Q RS
Sbjct: 210  STAYSHQRTFIMEVMGRHCGYLAIMAALASEADYVFIPEDPVVHNWPEKLCKKILQERSA 269

Query: 850  GQRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLG 1029
            GQRLNIIIV+EGAIDRDG  ITAE VK  V ++L+ DTR+T+LGHVQRGG PSAFDR+LG
Sbjct: 270  GQRLNIIIVSEGAIDRDGNPITAEKVKQVVVDRLQQDTRITVLGHVQRGGNPSAFDRVLG 329

Query: 1030 CRMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVML 1209
            CRMGAEAV ALME  +++EPCV+S+DGN  VRVPL++CVERT+ V KAM DK+W  AV L
Sbjct: 330  CRMGAEAVLALMEADDKTEPCVVSLDGNQAVRVPLMECVERTKAVAKAMEDKNWELAVQL 389

Query: 1210 RGRSFQRNLETYKLLTKMRTVEKDNLSEGH---KFNVAVINVGAPAGGMNAAVRSYVRMA 1380
            RGRSF RNLETYK+LT+++  +     +G     + +AV+++GAPA GMNAAVRS+VR
Sbjct: 390  RGRSFARNLETYKMLTRLKPPKSAFDEQGRGVGGYTMAVMHIGAPACGMNAAVRSFVRNC 449

Query: 1381 LYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQL 1560
            +Y   TV GI D  EGL  G  K+ +WSDVT W   GG+FLGT+++LP E     +AA+L
Sbjct: 450  IYRGDTVMGIHDGIEGLVAGHIKKMEWSDVTGWVGQGGAFLGTKRTLP-EGKFADIAARL 508

Query: 1561 KKHNIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTA 1740
            K+  IQALL+VGGFEAYH+   + + R K+ EFCIP+ VIP TISNN+PGT  SLG+DT
Sbjct: 509  KEFGIQALLIVGGFEAYHAAGQITDQRSKFKEFCIPIVVIPSTISNNMPGTEFSLGADTG 568

Query: 1741 INEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDL 1920
            +NEI ++ D+I+QSA GTKRRVF++ETMGGYCGYLATL+ L+ GAD AYI+EE FT++DL
Sbjct: 569  LNEITEICDRIRQSAQGTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFTIKDL 628

Query: 1921 SDDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQG 2100
              DV  + SKM  G +R L++RNE A +N  T+F+  L+  EGK  F+TR+NVLGH+QQG
Sbjct: 629  QQDVYHMASKMSDGVQRGLILRNEKASENYNTEFIYRLYSEEGKGLFSTRMNVLGHMQQG 688

Query: 2101 GSPTPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQ 2280
            GSPTPFDRNMGTK+AA+ +E+L+ QLK N   D  + A +  TA LLGL  R+  F+P++
Sbjct: 689  GSPTPFDRNMGTKMAAKCVEWLVEQLKANTQPDGSINATAPETACLLGLVRRQYKFSPLK 748

Query: 2281 DLKKETDFEHRLPSEQW 2331
            +L  ET+F  R+P  QW
Sbjct: 749  ELIGETNFMQRIPKHQW 765


>gi|34868102|ref|XP_346813.1| hypothetical protein XP_346812 [Rattus
            norvegicus]
          Length = 780

 Score =  829 bits (2141), Expect = 0.0
 Identities = 411/733 (56%), Positives = 542/733 (73%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ +A+ TSGGD+QGMN+AVR++ R+ I+ G +V+             + I+EATW +VS
Sbjct: 15   GKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGEHIREATWESVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             ++Q GGT+IGSAR  +FR REGRL+AA NL+ RGI  L  IGGDGSLTGA+TFR EW+D
Sbjct: 75   MMLQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSD 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ +L K+ ++TA  A K  Y+ IVGLVGSIDNDFCGTDMTIGTDSAL RI+  +DA+
Sbjct: 135  LLNDLQKDGKITAEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV +L+  AD+ FIPE P  ++W + LC +LS+ R+ G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIIIVAEGAID++GK IT+ED+K  V ++L YDTRVT+LGHVQRGG PSAFDR+LG
Sbjct: 255  SRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ V KAM +K +  A+ LR
Sbjct: 315  RMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKRFDEAIKLR 374

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF  N E YKLL  +R      +S+G    VAV+NVGAPA GMNAAVRS VR+ L
Sbjct: 375  GRSFMNNWEVYKLLAHVR----PPVSKGGLHTVAVMNVGAPAAGMNAAVRSTVRIGLIQG 430

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              V  + D FEGLA G  ++  WS V  W   GGS LGT+++LP +K + Q++A + K+N
Sbjct: 431  NRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLP-KKNLEQISANITKYN 489

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            IQ L+++GGFEAY   + L E R+++ E CIP  VIP T+SNNVPG+  S+G+DTA+N I
Sbjct: 490  IQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSIGADTALNTI 549

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
            C   D+IKQSA GTKRRVFI+ETMGGYCGYLAT++ L++GAD AYIFEEPFT++DL  +V
Sbjct: 550  CTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQVNV 609

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + ++ KM+   KR LV+RNE  ++N TTDF+ NL+  EGK  F +R NVLGH+QQGGSPT
Sbjct: 610  EHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPT 669

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN  TK+ A+A+ ++  ++KE+   + ++ A +  +  +LG++ R +VF PV +LK
Sbjct: 670  PFDRNFATKMGAKAMNWMSGKIKESY-RNGRIFANTPDSGCVLGMRKRALVFQPVTELKD 728

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 729  QTDFEHRIPKEQW 741


>gi|13638207|sp|P47857|K6PF_MOUSE 6-phosphofructokinase, muscle type
            (Phosphofructokinase 1) (Phosphohexokinase)
            (Phosphofructo-1-kinase isozyme A) (PFK-A)
            (Phosphofructokinase-M)
 gi|7547025|gb|AAF63762.1| phosphofructokinase-1 A isozyme [Mus
            musculus]
 gi|12832896|dbj|BAB22303.1| unnamed protein product [Mus musculus]
 gi|26340500|dbj|BAC33913.1| unnamed protein product [Mus musculus]
          Length = 780

 Score =  828 bits (2138), Expect = 0.0
 Identities = 411/733 (56%), Positives = 541/733 (73%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ +A+ TSGGD+QGMN+AVR++ R+ I+ G +V+             + I+EATW +VS
Sbjct: 15   GKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGEHIREATWESVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             ++Q GGT+IGSAR  +FR REGRL+AA NL+ RGI  L  IGGDGSLTGA+TFR EW+D
Sbjct: 75   MMLQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSD 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ +L K+ ++TA  A K  Y+ IVGLVGSIDNDFCGTDMTIGTDSAL RI+  +DA+
Sbjct: 135  LLNDLQKDGKITAEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV +L+  AD+ FIPE P  ++W + LC +LS+ R+ G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIIIVAEGAID++GK IT+ED+K  V ++L YDTRVT+LGHVQRGG PSAFDR+LG
Sbjct: 255  SRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ V KAM +K +  A+ LR
Sbjct: 315  RMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKRFDEAIKLR 374

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF  N E YKLL  +R      +S+G    VAV+NVGAPA GMNAAVRS VR+ L
Sbjct: 375  GRSFMNNWEVYKLLAHVR----PPVSKGGLHTVAVMNVGAPAAGMNAAVRSTVRIGLIQG 430

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              V  + D FEGLA G  ++  WS V  W   GGS LGT+++LP +K + Q++A + K N
Sbjct: 431  NRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLP-KKNLEQISANITKFN 489

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            IQ L+++GGFEAY   + L E R+++ E CIP  VIP T+SNNVPG+  S+G+DTA+N I
Sbjct: 490  IQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSIGADTALNTI 549

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
            C   D+IKQSA GTKRRVFI+ETMGGYCGYLAT++ L++GAD AYIFEEPFT++DL  +V
Sbjct: 550  CTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQVNV 609

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + ++ KM+   KR LV+RNE  ++N TTDF+ NL+  EGK  F +R NVLGH+QQGGSPT
Sbjct: 610  EHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPT 669

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN  TK+ A+A+ ++  ++KE+   + ++ A +  +  +LG++ R +VF PV +LK
Sbjct: 670  PFDRNFATKMGAKAMNWMSGKIKESY-RNGRIFANTPDSGCVLGMRKRALVFQPVTELKD 728

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 729  QTDFEHRIPKEQW 741


>gi|31981185|ref|NP_067489.2| phosphofructokinase, muscle;
            phosphofructokinase-1 A isozyme [Mus musculus]
 gi|13529638|gb|AAH05526.1| Phosphofructokinase, muscle [Mus musculus]
          Length = 780

 Score =  826 bits (2134), Expect = 0.0
 Identities = 410/733 (55%), Positives = 540/733 (72%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ +A+ TSGGD+QGMN+AVR++ R+ I+ G +V+             + I+EATW +VS
Sbjct: 15   GKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGEHIREATWESVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             ++Q GGT+IGSAR  +FR REGRL+AA NL+ RGI  L  IGGDGSLTGA+TFR EW+D
Sbjct: 75   MMLQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSD 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ +  K+ ++TA  A K  Y+ IVGLVGSIDNDFCGTDMTIGTDSAL RI+  +DA+
Sbjct: 135  LLNDFQKDGKITAEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV +L+  AD+ FIPE P  ++W + LC +LS+ R+ G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIIIVAEGAID++GK IT+ED+K  V ++L YDTRVT+LGHVQRGG PSAFDR+LG
Sbjct: 255  SRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ V KAM +K +  A+ LR
Sbjct: 315  RMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKRFDEAIKLR 374

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF  N E YKLL  +R      +S+G    VAV+NVGAPA GMNAAVRS VR+ L
Sbjct: 375  GRSFMNNWEVYKLLAHVR----PPVSKGGLHTVAVMNVGAPAAGMNAAVRSTVRIGLIQG 430

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              V  + D FEGLA G  ++  WS V  W   GGS LGT+++LP +K + Q++A + K N
Sbjct: 431  NRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLP-KKNLEQISANITKFN 489

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            IQ L+++GGFEAY   + L E R+++ E CIP  VIP T+SNNVPG+  S+G+DTA+N I
Sbjct: 490  IQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSIGADTALNTI 549

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
            C   D+IKQSA GTKRRVFI+ETMGGYCGYLAT++ L++GAD AYIFEEPFT++DL  +V
Sbjct: 550  CTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQVNV 609

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + ++ KM+   KR LV+RNE  ++N TTDF+ NL+  EGK  F +R NVLGH+QQGGSPT
Sbjct: 610  EHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPT 669

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN  TK+ A+A+ ++  ++KE+   + ++ A +  +  +LG++ R +VF PV +LK
Sbjct: 670  PFDRNFATKMGAKAMNWMSGKIKESY-RNGRIFANTPDSGCVLGMRKRALVFQPVTELKD 728

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 729  QTDFEHRIPKEQW 741


>gi|28557063|dbj|BAC57529.1| muscle-type phosphofructokinase [Equus
            caballus]
          Length = 780

 Score =  826 bits (2133), Expect = 0.0
 Identities = 413/733 (56%), Positives = 538/733 (73%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ +A+ TSGGD+QGMN+AVR++ R+ I+ G +V+             D I+EATW +VS
Sbjct: 15   GKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIREATWESVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             ++Q GGT+IGSAR  +FR REGRL+AA NL+  GI  L  IGGDGSLTGA+TFR EW+D
Sbjct: 75   MMLQLGGTVIGSARCKDFREREGRLRAAHNLVKLGITNLCVIGGDGSLTGADTFRSEWSD 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ +L K  ++TA  A K  Y+ IVGLVGSIDNDFCGTDMTIGTDSAL RII  +DA+
Sbjct: 135  LLSDLQKAGKITAEEATKSNYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIIEIVDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV +L+  AD+ FIPE P  ++W D LC +LS+ R+ G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEDHLCRRLSETRTRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIIIVAEGAIDR+GK IT+E +K  V ++L YDTRVT+LGHVQRGG PSAFDR+LG
Sbjct: 255  SRLNIIIVAEGAIDRNGKPITSESIKDLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ V KAMA++ +  A+ LR
Sbjct: 315  RMGVEAVMALLEATPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMAERKFDEAMKLR 374

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF  N E YKLL  +R      +S+     VAV+NVGAPA GMNAAVRS VR+ L
Sbjct: 375  GRSFMNNWEVYKLLAHIR----PPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQG 430

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              V  + D FEGLA G  ++  WS V  W   GGS LGT+++LP  K+  Q++A + K N
Sbjct: 431  NRVLVVHDGFEGLAKGRIEEAGWSYVGGWTGQGGSKLGTKRTLP-RKSFEQISANITKFN 489

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            IQ L++VGGFEAY   + L E R++Y E CIP  VIP T+SNNVPG+  S+G+DTA+N I
Sbjct: 490  IQGLIIVGGFEAYTGGLELMEGRKQYDELCIPFVVIPATVSNNVPGSDFSVGADTALNTI 549

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
            C   D+IKQSA GTKRRVFI+ETMGGYCGYLAT++ L++GAD AYIFEEPFT++DL  +V
Sbjct: 550  CMTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQVNV 609

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + ++ KM+   KR LV+RNE  ++N +TDF+ NL+  EGK  F +R NVLGH+QQGGSPT
Sbjct: 610  EHLVQKMKTTVKRGLVLRNEKCNENYSTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPT 669

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN  TK+ A+A+ ++  ++KE+   + ++ A +  +  +LG++ R +VF PV +LK+
Sbjct: 670  PFDRNFATKMGAKAMNWMSGKIKESY-RNGRIFANTPDSGCVLGMRKRALVFQPVTELKE 728

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 729  QTDFEHRIPKEQW 741


>gi|227448|prf||1704126A phosphofructokinase
          Length = 779

 Score =  824 bits (2129), Expect = 0.0
 Identities = 411/733 (56%), Positives = 538/733 (73%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ +A+ TSGGD+QGMN+AVR++ R+ I+ G +V+             D IKEATW +VS
Sbjct: 14   GKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVS 73

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             ++Q GGT+IGSAR  +FR REGRL+AA NL+ RGI  L  IGGDGSLTGA+TFR EW+D
Sbjct: 74   MMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSD 133

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ +L K  ++T   A K  Y+ IVGLVGSIDNDFCGTDMTIGTDSAL RI+  +DA+
Sbjct: 134  LLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITT 193

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV +L+  AD+ FIPE P  ++W + LC +LS+ R+ G
Sbjct: 194  TAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRG 253

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIIIVAEGAID++GK IT+ED+K  V ++L YDTRVT+LGHVQRGG PSAFDR+LG
Sbjct: 254  SRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGS 313

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ V KAM +K +  A+ LR
Sbjct: 314  RMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLR 373

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF  N E YKLL  +R      +S+     VAV+NVGAPA GMNAAVRS VR+ L
Sbjct: 374  GRSFMNNWEVYKLLAHVR----PPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQG 429

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              V  + D FEGLA G  ++  WS V  W   GGS LGT+++LP +K+  Q++A + K N
Sbjct: 430  NRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLP-KKSFEQISANITKFN 488

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            IQ L+++GGFEAY   + L E R+++ E CIP  VIP T+SNNVPG+  S+G+DTA+N I
Sbjct: 489  IQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTI 548

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
            C   D+IKQSA GTKRRVFI+ETMGGYCGYLAT++ L++GAD AYIFEEPFT++DL  +V
Sbjct: 549  CTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQANV 608

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + ++ KM+   KR LV+RNE  ++N TTDF+ NL+  EGK  F +R NVLGH+QQGGSPT
Sbjct: 609  EHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPT 668

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN  TK+ A+A+ ++  ++KE+   + ++ A +  +  +LG++ R +VF PV +LK
Sbjct: 669  PFDRNFATKMGAKAMNWMAGKIKESY-RNGRIFANTPDSGCVLGMRKRALVFQPVAELKD 727

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 728  QTDFEHRIPKEQW 740


>gi|33303855|gb|AAQ02441.1| phosphofructokinase, muscle [synthetic
            construct]
          Length = 781

 Score =  824 bits (2128), Expect = 0.0
 Identities = 411/733 (56%), Positives = 538/733 (73%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ +A+ TSGGD+QGMN+AVR++ R+ I+ G +V+             D IKEATW +VS
Sbjct: 15   GKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             ++Q GGT+IGSAR  +FR REGRL+AA NL+ RGI  L  IGGDGSLTGA+TFR EW+D
Sbjct: 75   MMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSD 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ +L K  ++T   A K  Y+ IVGLVGSIDNDFCGTDMTIGTDSAL RI+  +DA+
Sbjct: 135  LLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV +L+  AD+ FIPE P  ++W + LC +LS+ R+ G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIIIVAEGAID++GK IT+ED+K  V ++L YDTRVT+LGHVQRGG PSAFDR+LG
Sbjct: 255  SRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ V KAM +K +  A+ LR
Sbjct: 315  RMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLR 374

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF  N E YKLL  +R      +S+     VAV+NVGAPA GMNAAVRS VR+ L
Sbjct: 375  GRSFMNNWEVYKLLAHVR----PPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQG 430

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              V  + D FEGLA G  ++  WS V  W   GGS LGT+++LP +K+  Q++A + K N
Sbjct: 431  NRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLP-KKSFEQISANITKFN 489

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            IQ L+++GGFEAY   + L E R+++ E CIP  VIP T+SNNVPG+  S+G+DTA+N I
Sbjct: 490  IQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTI 549

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
            C   D+IKQSA GTKRRVFI+ETMGGYCGYLAT++ L++GAD AYIFEEPFT++DL  +V
Sbjct: 550  CTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQANV 609

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + ++ KM+   KR LV+RNE  ++N TTDF+ NL+  EGK  F +R NVLGH+QQGGSPT
Sbjct: 610  EHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPT 669

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN  TK+ A+A+ ++  ++KE+   + ++ A +  +  +LG++ R +VF PV +LK
Sbjct: 670  PFDRNFATKMGAKAMNWMSGKIKESY-RNGRIFANTPDSGCVLGMRKRALVFQPVAELKD 728

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 729  QTDFEHRIPKEQW 741


>gi|4505749|ref|NP_000280.1| phosphofructokinase, muscle;
            Phosphofructokinase, muscle type [Homo sapiens]
 gi|125126|sp|P08237|K6PF_HUMAN 6-phosphofructokinase, muscle type
            (Phosphofructokinase 1) (Phosphohexokinase)
            (Phosphofructo-1-kinase isozyme A) (PFK-A)
            (Phosphofructokinase-M)
 gi|1070470|pir||KIHUFM 6-phosphofructokinase (EC 2.7.1.11), muscle -
            human
 gi|32343|emb|CAA68692.1| unnamed protein product [Homo sapiens]
 gi|189855|gb|AAA60068.1| phosphofructokinase
 gi|1101758|gb|AAA82938.1| phosphofructokinase-M
 gi|12653525|gb|AAH00534.1| Phosphofructokinase, muscle [Homo sapiens]
 gi|15215397|gb|AAH12799.1| Phosphofructokinase, muscle [Homo sapiens]
 gi|15342053|gb|AAH13298.1| Phosphofructokinase, muscle [Homo sapiens]
 gi|18203737|gb|AAH21203.1| Phosphofructokinase, muscle [Homo sapiens]
          Length = 780

 Score =  824 bits (2128), Expect = 0.0
 Identities = 411/733 (56%), Positives = 538/733 (73%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ +A+ TSGGD+QGMN+AVR++ R+ I+ G +V+             D IKEATW +VS
Sbjct: 15   GKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             ++Q GGT+IGSAR  +FR REGRL+AA NL+ RGI  L  IGGDGSLTGA+TFR EW+D
Sbjct: 75   MMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSD 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ +L K  ++T   A K  Y+ IVGLVGSIDNDFCGTDMTIGTDSAL RI+  +DA+
Sbjct: 135  LLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV +L+  AD+ FIPE P  ++W + LC +LS+ R+ G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIIIVAEGAID++GK IT+ED+K  V ++L YDTRVT+LGHVQRGG PSAFDR+LG
Sbjct: 255  SRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ V KAM +K +  A+ LR
Sbjct: 315  RMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLR 374

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF  N E YKLL  +R      +S+     VAV+NVGAPA GMNAAVRS VR+ L
Sbjct: 375  GRSFMNNWEVYKLLAHVR----PPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQG 430

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              V  + D FEGLA G  ++  WS V  W   GGS LGT+++LP +K+  Q++A + K N
Sbjct: 431  NRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLP-KKSFEQISANITKFN 489

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            IQ L+++GGFEAY   + L E R+++ E CIP  VIP T+SNNVPG+  S+G+DTA+N I
Sbjct: 490  IQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTI 549

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
            C   D+IKQSA GTKRRVFI+ETMGGYCGYLAT++ L++GAD AYIFEEPFT++DL  +V
Sbjct: 550  CTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQANV 609

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + ++ KM+   KR LV+RNE  ++N TTDF+ NL+  EGK  F +R NVLGH+QQGGSPT
Sbjct: 610  EHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPT 669

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN  TK+ A+A+ ++  ++KE+   + ++ A +  +  +LG++ R +VF PV +LK
Sbjct: 670  PFDRNFATKMGAKAMNWMSGKIKESY-RNGRIFANTPDSGCVLGMRKRALVFQPVAELKD 728

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 729  QTDFEHRIPKEQW 741


>gi|1708593|sp|P52784|K6PF_CANFA 6-phosphofructokinase, muscle type
            (Phosphofructokinase 1) (Phosphohexokinase)
            (Phosphofructo-1-kinase isozyme A) (PFK-A)
            (Phosphofructokinase-M)
 gi|818847|gb|AAC48615.1| muscle type phosphofructokinase
 gi|1587715|prf||2207238A phosphofructokinase:ISOTYPE=muscle-type
          Length = 782

 Score =  823 bits (2127), Expect = 0.0
 Identities = 410/733 (55%), Positives = 538/733 (72%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ +A+ TSGGD+QGMN+AVR++ R+ I+ G +V+             D I+EATW +VS
Sbjct: 15   GKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIREATWESVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             ++Q GGT+IGSAR  +FR REGRL+AA NL+ RGI  L  IGGDGSLTGA+TFR EW+D
Sbjct: 75   MMLQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSD 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ +L K  ++TA  A K  Y+ IVGLVGSIDNDFCGTDMTIGTDSAL RII  +DA+
Sbjct: 135  LLSDLQKAGKITAEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIIEIVDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV +L+  AD+ FIPE P  ++W + LC +LS+ R+ G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIIIVAEGAID++GK IT+E++K  V ++L YDTRVT+LGHVQRGG PSAFDR+LG
Sbjct: 255  SRLNIIIVAEGAIDKNGKPITSEEIKELVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ V KAM D+ +  A+ LR
Sbjct: 315  RMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMNDRKFDEAMKLR 374

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF  N E YKLL  +R       +  H   VAV+NVGAPA GMNAAVRS VR+ L
Sbjct: 375  GRSFMNNWEVYKLLAHIRPPVSKTSATMH--TVAVMNVGAPAAGMNAAVRSTVRIGLIQG 432

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              V  + D FEGLA G  ++  WS V  W   GGS LGT+++LP +K+  Q++A + K N
Sbjct: 433  NRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLP-KKSFEQISANITKFN 491

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            IQ L+++GGFEAY   + L E R+++ E CIP  VIP T+SNNVPG+  S+G+DTA+N I
Sbjct: 492  IQGLIIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTI 551

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
            C   D+IKQSA GTKRRVFI+ETMGGYCGYLAT++ L++GAD AYIFEEPFT++DL  +V
Sbjct: 552  CTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQANV 611

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + ++ KM+   KR LV+RNE  ++N TTDF+ NL+  EGK  F +R NVLGH+QQGGSPT
Sbjct: 612  EHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPT 671

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN  TK+ A+A+ ++  ++KE+   + ++ A +  +  +LG++ R +VF PV +LK
Sbjct: 672  PFDRNFATKMGAKAMNWMSGKIKESY-RNGRIFANTPDSGCVLGMRKRALVFQPVTELKD 730

Query: 2293 ETDFEHRLPSEQW 2331
            +TDF+HR+P EQW
Sbjct: 731  QTDFDHRIPKEQW 743


>gi|34532659|dbj|BAC86498.1| unnamed protein product [Homo sapiens]
          Length = 851

 Score =  821 bits (2120), Expect = 0.0
 Identities = 410/733 (55%), Positives = 537/733 (72%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ +A+ TSGGD+QGMN+AVR++ R+ I+ G +V+             D IKEATW +VS
Sbjct: 86   GKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVS 145

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             ++Q GGT+IGSAR  +FR REGRL+AA NL+ RGI  L  IGGDGSLTGA+TFR EW+D
Sbjct: 146  MMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSD 205

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ +L K  ++T   A K  Y+ IVGLVGSIDNDFCGTDMTIGTDSAL RI+  +DA+
Sbjct: 206  LLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITT 265

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV +L+  AD+ FIPE P  ++W + LC +LS+ R+ G
Sbjct: 266  TAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRG 325

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIIIVAEGAID++GK IT+ED+K  V ++L YDTRVT+LGHVQRGG PSAFDR+LG
Sbjct: 326  SRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGS 385

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ V KAM +K +  A+ LR
Sbjct: 386  RMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLR 445

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF  N E YKLL  +R      +S+     VAV+NVGAPA GMNAAVRS VR+ L
Sbjct: 446  GRSFMNNWEVYKLLAHVR----PPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQG 501

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              V  + D FEGLA G  ++  WS V  W   GGS LGT+++LP +K+  Q++A + K N
Sbjct: 502  NRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLP-KKSFEQISANITKFN 560

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            IQ L+++GGFEAY   + L E R+++ E CIP  VIP T+SNNVPG+  S+G+DTA+N I
Sbjct: 561  IQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTI 620

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
            C   D+IKQSA GTKRRVFI+ETMGGYCGYLAT++ L++GAD AYIFEEPFT++DL  +V
Sbjct: 621  CTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQANV 680

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + ++ KM+   KR LV+RNE  ++N TTDF+ NL+  EGK  F +R NVLGH+QQGGSPT
Sbjct: 681  EHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPT 740

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
             FDRN  TK+ A+A+ ++  ++KE+   + ++ A +  +  +LG++ R +VF PV +LK
Sbjct: 741  SFDRNFATKMGAKAMNWMSGKIKESY-RNGRIFANTPDSGCVLGMRKRALVFQPVAELKD 799

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 800  QTDFEHRIPKEQW 812


>gi|13929002|ref|NP_113903.1| phosphofructokinase, muscle;
            phosphofructokinase-A [Rattus norvegicus]
 gi|2507173|sp|P47858|K6PF_RAT 6-phosphofructokinase, muscle type
            (Phosphofructokinase 1) (Phosphohexokinase)
            (Phosphofructo-1-kinase isozyme A) (PFK-A)
            (Phosphofructokinase-M)
 gi|7434213|pir||S71429 phosphofructokinase, muscle - rat
 gi|1536968|gb|AAC52786.1| phosphofructokinase muscle isozyme [Rattus
            norvegicus]
          Length = 780

 Score =  820 bits (2118), Expect = 0.0
 Identities = 407/733 (55%), Positives = 538/733 (72%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ +A+ TSGGD+QGMN+ VR++ R+ I+ G +V+             + I+EATW +VS
Sbjct: 15   GKAIAVLTSGGDAQGMNATVRAVVRVGIFTGLRVFFVHEGYQGLVDGGEHIREATWESVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             ++Q GGT+IGSAR  +FR REGRL+AA NL+ RGI  L  IGGDGSLTGA+TFR EW+D
Sbjct: 75   MMLQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSD 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ +L K+ ++TA    K  Y+ IV LVGSIDNDFCGTDMTIGTDSAL RI+  +DA+
Sbjct: 135  LLNDLQKDGKITAEERTKSSYLNIVFLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV +L+  AD+ FIPE P  ++W + LC +LS+ R+ G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIIIVAEGAID++GK IT+ED+K  V ++L YDTRVT+LGHVQRGG PSAFDR+LG
Sbjct: 255  SRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ V KAM +K +  A+ LR
Sbjct: 315  RMGVEAVMALLEGTPDTPACVVSLSGNTAVRLPLMECVQVTKDVTKAMDEKRFDEAIKLR 374

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF  N E YKLL  +R      +S+G    VAV+NVGAPA GMNAAVRS VR+ L
Sbjct: 375  GRSFMNNWEVYKLLAHVR----PPVSKGGLHTVAVMNVGAPAAGMNAAVRSTVRIGLIQG 430

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              V  + D FEGLA G  ++  WS V  W   GGS LGT+++LP +K + Q++A + K+N
Sbjct: 431  NRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLP-KKNLEQISANITKYN 489

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            IQ L+++GGFEAY   + L E R+++ E CIP  VIP T+SNNVPG+  S+G+DTA+N I
Sbjct: 490  IQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSIGADTALNTI 549

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
            C   D+IKQSA GTKRRVFI+ETMGGYCGYLAT++ L++GAD AYIFEEPFT++DL  +V
Sbjct: 550  CTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQVNV 609

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + ++ KM+   KR LV+RNE  ++N TTDF+ NL+  EGK  F +R NVLGH+QQGG+PT
Sbjct: 610  EHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGNPT 669

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN  TK+ A+A  ++  ++KE+   + ++ A +  +  +LG++ R +VF PV +LK
Sbjct: 670  PFDRNFATKMGAKATNWMSGKIKESY-RNGRIFANTPDSGCVLGMRKRALVFQPVTELKD 728

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 729  QTDFEHRIPKEQW 741


>gi|125128|sp|P00511|K6PF_RABIT 6-phosphofructokinase, muscle type
            (Phosphofructokinase 1) (Phosphohexokinase)
            (Phosphofructo-1-kinase isozyme A) (PFK-A)
            (Phosphofructokinase-M)
 gi|625216|pir||KIRBF 6-phosphofructokinase (EC 2.7.1.11), muscle -
            rabbit
 gi|165628|gb|AAA31441.1| phosphofructokinase
          Length = 780

 Score =  818 bits (2114), Expect = 0.0
 Identities = 410/733 (55%), Positives = 535/733 (72%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ +A+ TSGGD+QGMN+AVR++ R+ I+ G +V+             D I+EATW +VS
Sbjct: 15   GKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIREATWESVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             ++Q GGT+IGSAR  +FR REGRL+AA NL+ RGI  L  IGGDGSLTGA+TFR EW+D
Sbjct: 75   MMLQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSD 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ +L K  ++TA  A +  Y+ IVGLVGSIDNDFCGTDMTIGTDSAL RI   +DA+
Sbjct: 135  LLSDLQKAGKITAEEATRSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRITEIVDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV +L+  AD+ FIPE P  +NW D LC +LS+ R+ G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDNWEDHLCRRLSETRTRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIIIVAEGAIDR+GK IT+E VK  V  +L YDTRVT+LGHVQRGG PSAFDR+LG
Sbjct: 255  SRLNIIIVAEGAIDRNGKPITSEGVKDLVVRRLGYDTRVTVLGHVQRGGTPSAFDRILGS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ V KAM +K +  A+ LR
Sbjct: 315  RMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKRFDEAMKLR 374

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF  N E YKLL  +R     + S    + VAV+NVGAPA GMNAAVRS VR+ L
Sbjct: 375  GRSFMNNWEVYKLLAHIRPPAPKSGS----YTVAVMNVGAPAAGMNAAVRSTVRIGLIQG 430

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              V  + D FEG A G  ++  WS V  W   GGS LG++++LP +K+  Q++A + K N
Sbjct: 431  NRVLVVHDGFEGPAKGQIEEAGWSYVGGWTGQGGSKLGSKRTLP-KKSFEQISANITKFN 489

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            IQ L+++GGFEAY   + L E R+++ E CIP  VIP T+SNNVPG+  S+G+DTA+N I
Sbjct: 490  IQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTI 549

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
            C   D+IKQSA GTKRRVFI+ETMGGYCGYLAT++ L++GAD AYIFEEPFT++DL  +V
Sbjct: 550  CTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQANV 609

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + ++ KM+   KR LV+RNE  ++N TTDF+ NL+  EGK  F +R NVLGH+QQGGSPT
Sbjct: 610  EHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPT 669

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN  TK+ A+A+ ++  ++KE+   + ++ A +  +  +LG++ R +VF PV +L+
Sbjct: 670  PFDRNFATKMGAKAMNWMAGKIKESY-RNGRIFANTPDSGCVLGMRKRALVFQPVTELQN 728

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 729  QTDFEHRIPKEQW 741


>gi|1363065|pir||A53206 6-phosphofructokinase (EC 2.7.1.11) C - rabbit
          Length = 791

 Score =  814 bits (2103), Expect = 0.0
 Identities = 407/733 (55%), Positives = 529/733 (71%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++ RM IY G KVY               I EA W +VS
Sbjct: 24   GKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIVEANWESVS 83

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             I+Q GGTIIGSARS  FRTREGRLKAA NLI+RGI  L  IGGDGSLTGAN FR+EW+
Sbjct: 84   SILQVGGTIIGSARSKAFRTREGRLKAACNLIHRGITNLCVIGGDGSLTGANIFRMEWSG 143

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++EL ++ ++   A +K  Y+ +VG+VGSIDNDFCGTDMTIGTDSA  RII  IDA++
Sbjct: 144  LLEELAQDGKIDNEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSACHRIIEVIDAIMT 203

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+ALA  AD+ F+PE P  E W + +C KLS+ R++
Sbjct: 204  TAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRAQK 263

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
            +RLNIIIVAEGAID   + IT+E +K  V  +L YDTRVTILGHVQRGG PSAFDR+L
Sbjct: 264  KRLNIIIVAEGAIDTLNRPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILAS 323

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T E+  CV+S+ GN  VR+PL++CV+ TQ VQKAM ++ +  AV LR
Sbjct: 324  RMGVEAVLALLEATPETPACVVSLSGNHAVRLPLVECVQMTQEVQKAMDERRFKDAVQLR 383

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF+ NL TYK   ++     D+  +    NVAVINVGAPA GMNAAVRS VR+ +
Sbjct: 384  GRSFENNLNTYK---RLAIKLPDDKIQKSNCNVAVINVGAPAAGMNAAVRSAVRVGIADG 440

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              ++ + D F+G A G  K+ +W DV  W   GGS LGT++ LP  K + ++A Q++ HN
Sbjct: 441  HKMFAVYDGFDGFAKGQIKEIRWGDVGGWTGQGGSILGTKRILP-GKYLEEIATQIRTHN 499

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I A+L++GGFEAY   + L+  REK+ EFC+PM ++P T+SNNVPG+  S+G+DTA+N I
Sbjct: 500  INAILIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTI 559

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
                D+IKQSA+G+KRRVFI+ETMGGYCGYLA +  L++GAD AYIFEEPF ++DL  +V
Sbjct: 560  TDTCDRIKQSASGSKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNV 619

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + +  KM+   +R LV+RNE   +N TTDF+  L+  EG+  F  R NVLGH+QQGG+P+
Sbjct: 620  EHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGRGVFDCRKNVLGHMQQGGAPS 679

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTK++ARA++++  +LKE+     + +  S  +  +LG+  R V+F PV +LK
Sbjct: 680  PFDRNFGTKISARAMQWITTKLKESPGKGKRFV--SDDSICVLGISKRNVLFQPVAELKN 737

Query: 2293 ETDFEHRLPSEQW 2331
            ETDFEHR+P EQW
Sbjct: 738  ETDFEHRIPKEQW 750


>gi|1346356|sp|P47859|K6PP_RABIT 6-phosphofructokinase, type C
            (Phosphofructokinase 1) (Phosphohexokinase)
            (Phosphofructo-1-kinase isozyme C) (PFK-C)
 gi|393104|gb|AAA17707.1| phosphofructokinase C isozyme
          Length = 791

 Score =  813 bits (2101), Expect = 0.0
 Identities = 407/733 (55%), Positives = 528/733 (71%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++ RM IY G KVY               I EA W +VS
Sbjct: 24   GKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIVEANWESVS 83

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             I+Q GGTIIGSARS  FRTREGRLKAA NLI+RGI  L  IGG GSLTGAN FR+EW+
Sbjct: 84   SILQVGGTIIGSARSKAFRTREGRLKAACNLIHRGITNLCVIGGSGSLTGANIFRMEWSG 143

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++EL ++ ++   A +K  Y+ +VG+VGSIDNDFCGTDMTIGTDSA  RII  IDA++
Sbjct: 144  LLEELAQDGKIDNEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSACHRIIEVIDAIMT 203

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+ALA  AD+ F+PE P  E W + +C KLS+ R++
Sbjct: 204  TAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRAQK 263

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
            +RLNIIIVAEGAID   + IT+E +K  V  +L YDTRVTILGHVQRGG PSAFDR+L
Sbjct: 264  KRLNIIIVAEGAIDTLNRPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILAS 323

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T E+  CV+S+ GN  VR+PL++CV+ TQ VQKAM ++ +  AV LR
Sbjct: 324  RMGVEAVLALLEATPETPACVVSLSGNHAVRLPLVECVQMTQEVQKAMDERRFKDAVQLR 383

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF+ NL TYK   ++     D+  +    NVAVINVGAPA GMNAAVRS VR+ +
Sbjct: 384  GRSFENNLNTYK---RLAIKLPDDKIQKSNCNVAVINVGAPAAGMNAAVRSAVRVGIADG 440

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              ++ + D F+G A G  K+ +W DV  W   GGS LGT++ LP  K + ++A Q++ HN
Sbjct: 441  HKMFAVYDGFDGFAKGQIKEIRWGDVGGWTGQGGSILGTKRILP-GKYLEEIATQIRTHN 499

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I A+L++GGFEAY   + L+  REK+ EFC+PM ++P T+SNNVPG+  S+G+DTA+N I
Sbjct: 500  INAILIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTI 559

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
                D+IKQSA+GTKRRVFI+ETMGGYCGYLA +  L++GAD AYIFEEPF ++DL  +V
Sbjct: 560  TDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNV 619

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + +  KM+   +R LV+RNE   +N TTDF+  L+  EG+  F  R NVLGH+QQGG+P+
Sbjct: 620  EHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGRGVFDCRKNVLGHMQQGGAPS 679

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTK++ARA++++  +LKE+     + +  S  +  +LG+  R V+F PV +LK
Sbjct: 680  PFDRNFGTKISARAMQWITTKLKESPGKGKRFV--SDDSICVLGISKRNVLFQPVAELKN 737

Query: 2293 ETDFEHRLPSEQW 2331
            ETDFEHR+P EQW
Sbjct: 738  ETDFEHRIPKEQW 750


>gi|33303967|gb|AAQ02491.1| phosphofructokinase, platelet [synthetic
            construct]
          Length = 785

 Score =  811 bits (2094), Expect = 0.0
 Identities = 410/733 (55%), Positives = 522/733 (70%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++ RM IY G KVY               I EA W +VS
Sbjct: 24   GKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVS 83

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             I+Q GGTIIGSAR   FRTREGRLKAA NL+ RGI  L  IGGDGSLTGAN FR EW+
Sbjct: 84   SILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSG 143

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++EL +N ++   A +K  Y+ +VG+VGSIDNDFCGTDMTIGTDSAL RII  +DA++
Sbjct: 144  LLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMT 203

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+ALA  AD+ F+PE P  E W + +C KLS+ R+
Sbjct: 204  TAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARK 263

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
            +RLNIIIVAEGAID   K IT+E +K  V  +L YDTRVTILGHVQRGG PSAFDR+L
Sbjct: 264  KRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILAS 323

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S++GN  VR+PL++CV+ TQ VQKAM ++ +  AV LR
Sbjct: 324  RMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLR 383

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF  NL TYK   ++     D+       NVAVINVGAPA GMNAAVRS VR+ +
Sbjct: 384  GRSFAGNLNTYK---RLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADG 440

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              +  I D F+G A G  K+  W+DV  W   GGS LGT++ LP  K + ++A Q++ H+
Sbjct: 441  HRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLP-GKYLEEIATQMRTHS 499

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I ALL++GGFEAY   + L+  REK+ EFC+PM ++P T+SNNVPG+  S+G+DTA+N I
Sbjct: 500  INALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTI 559

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
                D+IKQSA+GTKRRVFI+ETMGGYCGYLA +  L++GAD AYIFEEPF ++DL  +V
Sbjct: 560  TDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNV 619

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + +  KM+   +R LV+RNE   +N TTDF+  L+  EGK  F  R NVLGH+QQGG+P+
Sbjct: 620  EHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPS 679

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTK++ARA+E++  +LKE      K       +  +LG+  R V+F PV +LKK
Sbjct: 680  PFDRNFGTKISARAMEWITAKLKEARGRGKKFTTDD--SICVLGISKRNVIFQPVAELKK 737

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 738  QTDFEHRIPKEQW 750


>gi|11321601|ref|NP_002618.1| phosphofructokinase, platelet;
            Phosphofructokinase, platelet type [Homo sapiens]
 gi|1346355|sp|Q01813|K6PP_HUMAN 6-phosphofructokinase, type C
            (Phosphofructokinase 1) (Phosphohexokinase)
            (Phosphofructo-1-kinase isozyme C) (PFK-C)
            (6-phosphofructokinase, platelet type)
 gi|625399|pir||JC2055 6-phosphofructokinase (EC 2.7.1.11), platelet -
            human
 gi|560105|dbj|BAA04998.1| platelet-type phosphofructokinase [Homo
            sapiens]
 gi|12803425|gb|AAH02536.1| Phosphofructokinase, platelet [Homo
            sapiens]
 gi|20810530|gb|AAH29138.1| Phosphofructokinase, platelet [Homo
            sapiens]
          Length = 784

 Score =  811 bits (2094), Expect = 0.0
 Identities = 410/733 (55%), Positives = 522/733 (70%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++ RM IY G KVY               I EA W +VS
Sbjct: 24   GKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVS 83

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             I+Q GGTIIGSAR   FRTREGRLKAA NL+ RGI  L  IGGDGSLTGAN FR EW+
Sbjct: 84   SILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSG 143

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++EL +N ++   A +K  Y+ +VG+VGSIDNDFCGTDMTIGTDSAL RII  +DA++
Sbjct: 144  LLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMT 203

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+ALA  AD+ F+PE P  E W + +C KLS+ R+
Sbjct: 204  TAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARK 263

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
            +RLNIIIVAEGAID   K IT+E +K  V  +L YDTRVTILGHVQRGG PSAFDR+L
Sbjct: 264  KRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILAS 323

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S++GN  VR+PL++CV+ TQ VQKAM ++ +  AV LR
Sbjct: 324  RMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLR 383

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF  NL TYK   ++     D+       NVAVINVGAPA GMNAAVRS VR+ +
Sbjct: 384  GRSFAGNLNTYK---RLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADG 440

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              +  I D F+G A G  K+  W+DV  W   GGS LGT++ LP  K + ++A Q++ H+
Sbjct: 441  HRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLP-GKYLEEIATQMRTHS 499

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I ALL++GGFEAY   + L+  REK+ EFC+PM ++P T+SNNVPG+  S+G+DTA+N I
Sbjct: 500  INALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTI 559

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
                D+IKQSA+GTKRRVFI+ETMGGYCGYLA +  L++GAD AYIFEEPF ++DL  +V
Sbjct: 560  TDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNV 619

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + +  KM+   +R LV+RNE   +N TTDF+  L+  EGK  F  R NVLGH+QQGG+P+
Sbjct: 620  EHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPS 679

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTK++ARA+E++  +LKE      K       +  +LG+  R V+F PV +LKK
Sbjct: 680  PFDRNFGTKISARAMEWITAKLKEARGRGKKFTTDD--SICVLGISKRNVIFQPVAELKK 737

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 738  QTDFEHRIPKEQW 750


>gi|34784595|gb|AAH57710.1| MGC68847 protein [Xenopus laevis]
          Length = 784

 Score =  809 bits (2089), Expect = 0.0
 Identities = 406/736 (55%), Positives = 533/736 (72%), Gaps = 2/736 (0%)
 Frame = +1

Query: 130  KGRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTV 309
            KG+ + + TSGGD+QGMN+AVR++ RM IY   KVY             D I+E +W +V
Sbjct: 15   KGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVQAKVYFIYEGYQGMVDGGDNIEEVSWESV 74

Query: 310  SDIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWT 489
            S I+Q GGT+IGSAR   FR REGRL+AA NL+ RGI  L  IGGDGSLTGAN FR EW+
Sbjct: 75   SSILQVGGTVIGSARCKSFRNREGRLQAACNLVQRGITNLCVIGGDGSLTGANLFREEWS 134

Query: 490  DLVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVV 669
             L+ ELV+  ++ A AAK+  ++ IVG+VGSIDNDFCGTDMTIGTDSAL RI+  +DA++
Sbjct: 135  GLLDELVQTGKIEAEAAKEYAHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIMEVVDAIM 194

Query: 670  ATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSE 849
             TA SHQR FV+EVMGRHCGYLALV+ALA  AD+ FIPE P  E W D++C+KLS+ R+
Sbjct: 195  TTALSHQRTFVLEVMGRHCGYLALVSALACGADWMFIPESPPEEGWEDLMCNKLSENRAR 254

Query: 850  GQRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLG 1029
             +RLNIIIV+EGAID   K IT++ VK  V ++L +DTRVTILGHVQRGG PSAFDR+L
Sbjct: 255  KKRLNIIIVSEGAIDCHNKPITSDLVKDLVVKRLGFDTRVTILGHVQRGGTPSAFDRILA 314

Query: 1030 CRMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVML 1209
             RMG + V AL+E T E+  CV+S+ GN  VR+PL++CV+ TQ VQKAM ++ +  AV L
Sbjct: 315  SRMGVDCVLALLEATPETPACVVSLCGNQAVRLPLMECVQMTQEVQKAMDERRFEDAVRL 374

Query: 1210 RGRSFQRNLETYKLLTKMRTVEKDNLSEGHK--FNVAVINVGAPAGGMNAAVRSYVRMAL 1383
            RGRSF+ NL TYKLL+      K N+SE  K  FNVAV+NVGAPA GMNAAVRS VR+ +
Sbjct: 375  RGRSFENNLNTYKLLS-----HKKNISELPKSNFNVAVLNVGAPAAGMNAAVRSAVRVGI 429

Query: 1384 YHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLK 1563
                 ++ + D FEG A G  K+ KW  V  W   GGS LGT+++LP  K   Q+A Q++
Sbjct: 430  TEGHKMFAVNDGFEGFAKGQIKEIKWGGVGGWTGQGGSLLGTKRTLPA-KYFDQIAEQIR 488

Query: 1564 KHNIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAI 1743
             + I ALL++GGFEA+   + + E R KY EFCIPM ++P T+SNNVPG+  S+G+DTA+
Sbjct: 489  TNKIHALLVIGGFEAFLGLLEMVEGRGKYDEFCIPMVMVPATVSNNVPGSDFSIGADTAL 548

Query: 1744 NEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLS 1923
            N I    D+IKQSA+GTKRRVFI+ETMGGYCGYLA +  L++GAD AYIFEE F +++L
Sbjct: 549  NTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEESFDIRELQ 608

Query: 1924 DDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGG 2103
             +V+ +  KM+   +R L++RNE +++N TTDF+  L+  EG+  F  R NVLGH+QQGG
Sbjct: 609  ANVEHLTEKMKTSIQRGLILRNENSNENYTTDFIYQLYSEEGRGVFDCRKNVLGHMQQGG 668

Query: 2104 SPTPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQD 2283
            +P+PFDRN GTK++A+A++++  +LKE    + +V A +  +  LLG++ R ++F PV
Sbjct: 669  APSPFDRNFGTKISAKAVQWISKKLKETY-RNGRVFANTDDSVCLLGMRRRNLLFQPVTQ 727

Query: 2284 LKKETDFEHRLPSEQW 2331
            LK ETDF+HR+P EQW
Sbjct: 728  LKDETDFKHRIPREQW 743


>gi|23821298|dbj|BAC20931.1| phosphofructokinase [Gallus gallus]
          Length = 770

 Score =  805 bits (2079), Expect = 0.0
 Identities = 404/733 (55%), Positives = 526/733 (71%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G  +A+ TSGGD+QGMN+AVR++TRM IY G KV+L            D IK+ATW +VS
Sbjct: 5    GMAIAVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGDNIKQATWLSVS 64

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
            +IIQ GGT+IGSAR   F TR+GR   A NL+  GI  L  IGGDGSLTGA+ FR EW
Sbjct: 65   NIIQLGGTVIGSARCKAFTTRQGRCAPARNLVEHGITNLCVIGGDGSLTGADVFRAEWAG 124

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ EL+++  ++   AK    + +VGLVGSIDNDFCGTDMTIGTDSAL RI+  IDA+
Sbjct: 125  LLDELLRDGLISEEVAKANGRLNVVGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITT 184

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+ LAS AD+ FIPE P  + W D++C++L + RS G
Sbjct: 185  TAQSHQRTFVLEVMGRHCGYLALVSGLASGADWLFIPESPPEDGWEDLMCERLGETRSRG 244

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIII+AEGAIDR+GK I++  VK  V ++L +DTRVT+LGHVQR G PSAFDR+L
Sbjct: 245  SRLNIIIIAEGAIDRNGKPISSNYVKDLVVQRLGFDTRVTVLGHVQRVGTPSAFDRVLSS 304

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            +MG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ VQKAM +K +  A+ LR
Sbjct: 305  KMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEKRFDEAIQLR 364

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF+ N   YKLL   +  +     E   F++A++NVGAPA GMNAAVRS VR+++
Sbjct: 365  GRSFENNWNIYKLLAHQKPAQ-----EKSPFSLAILNVGAPAAGMNAAVRSAVRISICRG 419

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
             T+Y + D FEGLA G  ++  W DV  W   GGS LGT+++LP +  M ++   ++K N
Sbjct: 420  HTIYAVSDGFEGLAKGQIREVGWHDVAGWLGRGGSMLGTKRTLP-KTCMEKIVENVRKFN 478

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            IQ LL++GGFEAY   + L E R +Y E CI MCVIP TISNNVPGT  SLGSDTA+N
Sbjct: 479  IQGLLVIGGFEAYEGVLQLVEARGQYEELCIIMCVIPATISNNVPGTDFSLGSDTAVNAA 538

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
             +  D+IKQSA+GT RRVFIVETMGGYCGYL T++ ++ GAD AY++E+PFT+ DL  +V
Sbjct: 539  MESCDRIKQSASGTTRRVFIVETMGGYCGYLCTVTGIAVGADAAYVYEDPFTIHDLKANV 598

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + +  KM+   +R LV+RNE   ++ TT+F+ NL+ SEGK  F  R+NVLGH+QQGG+PT
Sbjct: 599  EHLTDKMKTDIQRGLVLRNEKCHEHYTTEFLYNLYSSEGKGIFDCRINVLGHLQQGGAPT 658

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTKL  +A+ ++  +L+E      +V A SA +A ++GL+ + V F+PV +LKK
Sbjct: 659  PFDRNYGTKLGVKAVLWMSEKLQE-AYRKGRVFANSADSACVIGLRKKVVAFSPVTELKK 717

Query: 2293 ETDFEHRLPSEQW 2331
             TDFEHRLP EQW
Sbjct: 718  VTDFEHRLPQEQW 730


>gi|31560653|ref|NP_032852.2| phosphofructokinase, liver, B-type [Mus
            musculus]
 gi|18043646|gb|AAH20097.1| Phosphofructokinase, liver, B-type [Mus
            musculus]
 gi|26326507|dbj|BAC26997.1| unnamed protein product [Mus musculus]
 gi|26331304|dbj|BAC29382.1| unnamed protein product [Mus musculus]
 gi|26349107|dbj|BAC38193.1| unnamed protein product [Mus musculus]
          Length = 780

 Score =  805 bits (2078), Expect = 0.0
 Identities = 407/734 (55%), Positives = 529/734 (71%), Gaps = 1/734 (0%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++TRM IY G KV+L            + IK A W +VS
Sbjct: 15   GKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKPANWLSVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
            +IIQ GGTIIGSAR   F TREGRL AA NL+  GI  L  IGGDGSLTGAN FR EW
Sbjct: 75   NIIQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDGSLTGANIFRNEWGS 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++ELVK  +++ + A+   ++ I GLVGSIDNDFCGTDMTIGTDSAL RI+  IDA+
Sbjct: 135  LLEELVKEGKISESTAQNYAHLTIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+ALAS AD+ FIPE P  + W + +C++L + RS G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIII+AEGAIDR GK I++  VK  V ++L +DTRVT+LGHVQRGG PSAFDR+L
Sbjct: 255  SRLNIIIIAEGAIDRHGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            +MG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ VQKAM ++ +  A+ LR
Sbjct: 315  KMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEERFDEAIQLR 374

Query: 1213 GRSFQRNLETYKLLTKMR-TVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYH 1389
            GRSF+ N + YKLL   + + EK N      F++A++NVGAPA GMNAAVRS VR  +
Sbjct: 375  GRSFENNWKIYKLLAHQKVSKEKSN------FSLAILNVGAPAAGMNAAVRSAVRTGISE 428

Query: 1390 QCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKH 1569
              TVY + D FEGLA G  ++  W DV  W   GGS LGT+++LP +  +  +   L+ +
Sbjct: 429  GHTVYIVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLP-KPHLEAIVENLRTY 487

Query: 1570 NIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINE 1749
            NI ALL++GGFEAY   + L E R +Y E CI MCVIP TISNNVPGT  SLGSDTA+N
Sbjct: 488  NIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNA 547

Query: 1750 ICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDD 1929
              +  D+IKQSA+GTKRRVFIVETMGGYCGYLAT++ ++ GAD AY+FE+PF + DL  +
Sbjct: 548  AMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKAN 607

Query: 1930 VDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSP 2109
            V+ +  KM+   +R LV+RNE   ++ TT+F+ NL+ SEG+  F  R NVLGH+QQGG+P
Sbjct: 608  VEHMTEKMKTDIQRGLVLRNEKCHEHYTTEFLYNLYSSEGRGVFDCRTNVLGHLQQGGAP 667

Query: 2110 TPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLK 2289
            TPFDRN GTKL  +A+ ++  +L++ +    +V A +  +A ++GL+ + V F+PV +LK
Sbjct: 668  TPFDRNYGTKLGVKAMLWVSEKLRD-VYRKGRVFANAPDSACVIGLRKKVVAFSPVTELK 726

Query: 2290 KETDFEHRLPSEQW 2331
            KETDFEHR+P EQW
Sbjct: 727  KETDFEHRMPREQW 740


>gi|6981352|ref|NP_037322.1| phosphofructokinase, liver, B-type
            [Rattus norvegicus]
 gi|400095|sp|P30835|K6PL_RAT 6-phosphofructokinase, liver type
            (Phosphofructokinase 1) (Phosphohexokinase)
            (Phosphofructo-1-kinase isozyme B) (PFK-B)
 gi|111316|pir||S19689 6-phosphofructokinase (EC 2.7.1.11) - rat
 gi|56887|emb|CAA41674.1| 6-phosphofructokinase [Rattus norvegicus]
          Length = 780

 Score =  804 bits (2076), Expect = 0.0
 Identities = 407/734 (55%), Positives = 528/734 (71%), Gaps = 1/734 (0%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++TRM IY G KV+L            + IK A W +VS
Sbjct: 15   GKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKPANWLSVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
            +IIQ GGTIIGSAR   F TREGRL AA NL+  GI  L  IGGDGSLTGAN FR EW
Sbjct: 75   NIIQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDGSLTGANIFRNEWGS 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++ELVK  +++ + A+   ++ I GLVGSIDNDFCGTDMTIGTDSAL RI+  IDA+
Sbjct: 135  LLEELVKEGKISESTAQNYAHLSIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+ALAS AD+ FIPE P  + W + +C++L + RS G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIII+AEGAIDR GK I++  VK  V ++L +DTRVT+LGHVQRGG PSAFDR+L
Sbjct: 255  SRLNIIIIAEGAIDRHGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRVLSS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            +MG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ VQKAM +K +  A+ LR
Sbjct: 315  KMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEKRFDEAIQLR 374

Query: 1213 GRSFQRNLETYKLLTKMR-TVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYH 1389
            GRSF+ N + YKLL   + + EK N      F++A++NVGAPA GMNAAVRS VR  +
Sbjct: 375  GRSFENNWKIYKLLAHQKVSKEKSN------FSLAILNVGAPAAGMNAAVRSAVRTGISE 428

Query: 1390 QCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKH 1569
              TVY + D FEGLA G  ++  W DV  W   GGS LGT+++LP +  +  +   L+ +
Sbjct: 429  GHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLP-KPHLEAIVENLRTY 487

Query: 1570 NIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINE 1749
            NI ALL++GGFEAY   + L E R +Y E CI MCVIP TISNNVPGT  SLGSDTA+N
Sbjct: 488  NIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNA 547

Query: 1750 ICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDD 1929
              +  D+IKQSA+GTKRRVFIVETMGGYCGYLAT++ ++ GAD AY+FE+PF + DL  +
Sbjct: 548  AMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKAN 607

Query: 1930 VDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSP 2109
            V+ +  KM+   +R LV+RNE   ++ TT+F+ NL+ SEG+  F  R NVLGH+QQGG+P
Sbjct: 608  VEHMTEKMKTDIQRGLVLRNEKCHEHYTTEFLYNLYSSEGRGVFDCRTNVLGHLQQGGAP 667

Query: 2110 TPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLK 2289
            TPFDRN GTKL  +A+ ++  +L++ +    +V A +  +A ++GL+ + V F+ V +LK
Sbjct: 668  TPFDRNYGTKLGVKAMLWMSEKLRD-VYRKGRVFANAPDSACVIGLRKKVVAFSSVTELK 726

Query: 2290 KETDFEHRLPSEQW 2331
            KETDFEHR+P EQW
Sbjct: 727  KETDFEHRMPREQW 740


>gi|35431|emb|CAA33597.1| unnamed protein product [Homo sapiens]
          Length = 780

 Score =  804 bits (2076), Expect = 0.0
 Identities = 408/733 (55%), Positives = 521/733 (70%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD QGMN+AVR++TRM IY G KV+L            + IK+A W +VS
Sbjct: 15   GKAIGVLTSGGDRQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
            +IIQ GGTIIGSARS  F TREGR  AA NL+  GI  L  IGGDGSLTGAN FR EW
Sbjct: 75   NIIQLGGTIIGSARSKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGS 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++ELV   +++   A    ++ I GLVGSIDNDFCGTDMTIGTDSAL RI+  IDA+
Sbjct: 135  LLEELVAEGKISETTAWTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+ALAS AD+ FIPE P  + W + +C++L + RS G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIII+AEGAIDR+GK I++  VK  V ++L +DTRVT+LGHVQRGG PSAFDR+L
Sbjct: 255  SRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            +MG EAV AL+E T ++  CV+++ GN  VR+PL++CV+ T+ VQKAM DK +  A  LR
Sbjct: 315  KMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLR 374

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            G SF+ N   YKLLT  +  +     E   F++A++NVGAPA GMNAAVRS VR  + H
Sbjct: 375  GGSFENNWNIYKLLTHQKPPK-----EKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHG 429

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
             TVY + D FEGLA G  ++  W DV  W   GGS LGT+++LP +  +  +   ++ +
Sbjct: 430  HTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLP-KGQLESIVENIRIYG 488

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I ALL+VGGFEAY   + L E R +Y E CI MCVIP TISNNVPGT  SLGSDTA+N
Sbjct: 489  IHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAA 548

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
             +  D+IKQSA+GTKRRVFIVETMGGYCGYLAT++ ++ GAD AY+FE+PF + DL  +V
Sbjct: 549  MESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNV 608

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + +  KM+   +R LV+RNE      TT+F+ NL+ SEGK  F  R NVLGH+QQGG+PT
Sbjct: 609  EHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPT 668

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTKL  +A+ +L  +L+E +    +V A +  +A ++GLK + V F+PV +LKK
Sbjct: 669  PFDRNYGTKLGVKAMLWLSEKLRE-VYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKK 727

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 728  DTDFEHRMPREQW 740


>gi|38197562|gb|AAH61791.1| Phosphofructokinase, liver, B-type [Rattus
            norvegicus]
          Length = 780

 Score =  804 bits (2076), Expect = 0.0
 Identities = 407/734 (55%), Positives = 528/734 (71%), Gaps = 1/734 (0%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++TRM IY G KV+L            + IK A W +VS
Sbjct: 15   GKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKPANWLSVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
            +IIQ GGTIIGSAR   F TREGRL AA NL+  GI  L  IGGDGSLTGAN FR EW
Sbjct: 75   NIIQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDGSLTGANIFRNEWGS 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++ELVK  +++ + A+   ++ I GLVGSIDNDFCGTDMTIGTDSAL RI+  IDA+
Sbjct: 135  LLEELVKEGKISESTAQNYAHLSIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+ALAS AD+ FIPE P  + W + +C++L + RS G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIII+AEGAIDR GK I++  VK  V ++L +DTRVT+LGHVQRGG PSAFDR+L
Sbjct: 255  SRLNIIIIAEGAIDRHGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRVLSS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            +MG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ VQKAM +K +  A+ LR
Sbjct: 315  KMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEKRFDEAIQLR 374

Query: 1213 GRSFQRNLETYKLLTKMR-TVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYH 1389
            GRSF+ N + YKLL   + + EK N      F++A++NVGAPA GMNAAVRS VR  +
Sbjct: 375  GRSFENNWKIYKLLAHQKVSKEKSN------FSLAILNVGAPAAGMNAAVRSAVRTGISE 428

Query: 1390 QCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKH 1569
              TVY + D FEGLA G  ++  W DV  W   GGS LGT+++LP +  +  +   L+ +
Sbjct: 429  GHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLP-KPHLEAIVENLRTY 487

Query: 1570 NIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINE 1749
            NI ALL++GGFEAY   + L E R +Y E CI MCVIP TISNNVPGT  SLGSDTA+N
Sbjct: 488  NIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNA 547

Query: 1750 ICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDD 1929
              +  D+IKQSA+GTKRRVFIVETMGGYCGYLAT++ ++ GAD AY+FE+PF + DL  +
Sbjct: 548  AMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKAN 607

Query: 1930 VDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSP 2109
            V+ +  KM+   +R LV+RNE   ++ TT+F+ NL+ SEG+  F  R NVLGH+QQGG+P
Sbjct: 608  VEHMTEKMKTDIQRGLVLRNEKCHEHYTTEFLYNLYSSEGRGVFDCRTNVLGHLQQGGAP 667

Query: 2110 TPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLK 2289
            TPFDRN GTKL  +A+ ++  +L++ +    +V A +  +A ++GL+ + V F+ V +LK
Sbjct: 668  TPFDRNYGTKLGVKAMLWMSEKLRD-VYRKGRVFANAPDSACVIGLRKKVVAFSSVTELK 726

Query: 2290 KETDFEHRLPSEQW 2331
            KETDFEHR+P EQW
Sbjct: 727  KETDFEHRMPREQW 740


>gi|45361279|ref|NP_989217.1| hypothetical protein MGC75635 [Xenopus
            tropicalis]
 gi|38648948|gb|AAH63195.1| Hypothetical protein MGC75635 [Xenopus
            tropicalis]
          Length = 802

 Score =  803 bits (2074), Expect = 0.0
 Identities = 407/752 (54%), Positives = 531/752 (70%), Gaps = 18/752 (2%)
 Frame = +1

Query: 130  KGRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTV 309
            KG+ + + TSGGD+QGMN+AVR++ RM IY   KVY             D I+E +W +V
Sbjct: 15   KGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVQAKVYFIYEGYQGMVDGGDNIEEVSWESV 74

Query: 310  SDIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWT 489
            S I+Q GGT+IGSAR   FRTREGRL+AA NL+ RGI  L  IGGDGSLTGAN FR EW+
Sbjct: 75   SSILQVGGTVIGSARCKAFRTREGRLQAAYNLVQRGITNLCVIGGDGSLTGANLFREEWS 134

Query: 490  DLVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVV 669
             L+ EL++N ++ A A ++  ++ IVG+VGSIDNDFCGTDMTIGTDSAL RII  +DA++
Sbjct: 135  GLLDELMQNGKIEAEATREYAHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIM 194

Query: 670  ATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSE 849
             TAQSHQR FV+EVMGRHCGYLALV+ALA  AD+ FIPE+P  E W D++C+KLS+ R+
Sbjct: 195  TTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFIPEYPPEEGWEDMMCNKLSENRAR 254

Query: 850  GQRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLG 1029
             +RLNIIIV+EGAID   KAIT++ VK  V ++L +DTRVTILGHVQRGG PSAFDR+L
Sbjct: 255  KKRLNIIIVSEGAIDCHNKAITSDMVKDLVVKRLGFDTRVTILGHVQRGGTPSAFDRILA 314

Query: 1030 CRMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVML 1209
             RMG + V AL+E T E+  CV+S+ GN  VR+PL++CV+ TQ VQKAM ++ +  AV L
Sbjct: 315  SRMGVDCVLALLEATPETPACVVSLCGNQAVRLPLMECVQMTQEVQKAMDERRFDDAVRL 374

Query: 1210 RGRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYH 1389
            RGRSF+ NL TYKLL+  + V     S    F VAV+NVGAPA GMNAAVRS VR+ +
Sbjct: 375  RGRSFENNLNTYKLLSHKKNVADLPKS---NFTVAVLNVGAPAAGMNAAVRSAVRVGITE 431

Query: 1390 QCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKH 1569
               +  + D FEG A G  K  KW DV  W   GGS LGT+++LP  K   ++A Q++ H
Sbjct: 432  GHKMLAVNDGFEGFAKGQIKDIKWGDVGGWTGQGGSLLGTKRTLPA-KYFDKIAEQIRTH 490

Query: 1570 NIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINE 1749
             I ALL++GGFEAY   + + E R KY EFCIPM ++P T+SNNVPG+  S+G+DTA+N
Sbjct: 491  KINALLVIGGFEAYLGLMEMVEGRGKYDEFCIPMVMVPATVSNNVPGSDFSIGADTALNT 550

Query: 1750 ICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDD 1929
            I    D+IKQSA+GTKRRVFI+ETMGGYCGYLA +  L++GAD AYIFEE F +++L  +
Sbjct: 551  ITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEESFDIRELQAN 610

Query: 1930 VDVILSKMEVGAKRYLV------------------VRNEWADKNLTTDFVQNLFDSEGKK 2055
            V+ +  KM+   +R LV                  +RNE +++N TTDF+  L+  EG+
Sbjct: 611  VEHLTEKMKTSIQRGLVLRPRLFIDQPPIQTTPRLLRNENSNENYTTDFIYQLYSEEGRG 670

Query: 2056 NFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTAT 2235
             F  R NVLGH+QQGG+P+PFDRN GTK++A+A++++  +LKE      +V A +  +
Sbjct: 671  VFDCRKNVLGHMQQGGAPSPFDRNFGTKISAKAVQWISKKLKETY-RKGRVFANTDDSVC 729

Query: 2236 LLGLKGRKVVFTPVQDLKKETDFEHRLPSEQW 2331
            LLG++ R ++F PV  LK ETDF+HR+P EQW
Sbjct: 730  LLGMRRRNLLFQPVTQLKDETDFKHRIPKEQW 761


>gi|33303747|gb|AAQ02387.1| phosphofructokinase, liver [synthetic
            construct]
          Length = 781

 Score =  803 bits (2073), Expect = 0.0
 Identities = 406/733 (55%), Positives = 521/733 (70%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++TRM IY G KV+L            + IK+A W +VS
Sbjct: 15   GKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
            +IIQ GGTIIGSAR   F TREGR  AA NL+  GI  L  IGGDGSLTGAN FR EW
Sbjct: 75   NIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGS 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++ELV   +++   A+   ++ I GLVGSIDNDFCGTDMTIGTDSAL RI+  IDA+
Sbjct: 135  LLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+ALAS AD+ FIPE P  + W + +C++L + RS G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIII+AEGAIDR+GK I++  VK  V ++L +DTRVT+LGHVQRGG PSAFDR+L
Sbjct: 255  SRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            +MG EAV AL+E T ++  CV+++ GN  VR+PL++CV+ T+ VQKAM DK +  A  LR
Sbjct: 315  KMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLR 374

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            G SF+ N   YKLL   +  +     E   F++A++NVGAPA GMNAAVRS VR  + H
Sbjct: 375  GGSFENNWNIYKLLAHQKPPK-----EKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHG 429

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
             TVY + D FEGLA G  ++  W DV  W   GGS LGT+++LP +  +  +   ++ +
Sbjct: 430  HTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLP-KGQLESIVENIRIYG 488

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I ALL+VGGFEAY   + L E R +Y E CI MCVIP TISNNVPGT  SLGSDTA+N
Sbjct: 489  IHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAA 548

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
             +  D+IKQSA+GTKRRVFIVETMGGYCGYLAT++ ++ GAD AY+FE+PF + DL  +V
Sbjct: 549  MESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNV 608

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + +  KM+   +R LV+RNE      TT+F+ NL+ SEGK  F  R NVLGH+QQGG+PT
Sbjct: 609  EHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPT 668

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTKL  +A+ +L  +L+E +    +V A +  +A ++GLK + V F+PV +LKK
Sbjct: 669  PFDRNYGTKLGVKAMLWLSEKLRE-VYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKK 727

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 728  DTDFEHRMPREQW 740


>gi|48762920|ref|NP_002617.3| liver phosphofructokinase isoform b;
            6-phosphofructokinase, liver type; liver-type
            1-phosphofructokinase; phosphofructokinase 1;
            phosphohexokinase; phosphofructo-1-kinase isozyme B [Homo
            sapiens]
 gi|7768777|dbj|BAA95561.1| liver-type 1-phosphofructokinase [Homo
            sapiens]
 gi|14043101|gb|AAH07536.1| Liver phosphofructokinase [Homo sapiens]
          Length = 780

 Score =  803 bits (2073), Expect = 0.0
 Identities = 406/733 (55%), Positives = 521/733 (70%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++TRM IY G KV+L            + IK+A W +VS
Sbjct: 15   GKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
            +IIQ GGTIIGSAR   F TREGR  AA NL+  GI  L  IGGDGSLTGAN FR EW
Sbjct: 75   NIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGS 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++ELV   +++   A+   ++ I GLVGSIDNDFCGTDMTIGTDSAL RI+  IDA+
Sbjct: 135  LLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+ALAS AD+ FIPE P  + W + +C++L + RS G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIII+AEGAIDR+GK I++  VK  V ++L +DTRVT+LGHVQRGG PSAFDR+L
Sbjct: 255  SRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            +MG EAV AL+E T ++  CV+++ GN  VR+PL++CV+ T+ VQKAM DK +  A  LR
Sbjct: 315  KMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLR 374

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            G SF+ N   YKLL   +  +     E   F++A++NVGAPA GMNAAVRS VR  + H
Sbjct: 375  GGSFENNWNIYKLLAHQKPPK-----EKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHG 429

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
             TVY + D FEGLA G  ++  W DV  W   GGS LGT+++LP +  +  +   ++ +
Sbjct: 430  HTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLP-KGQLESIVENIRIYG 488

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I ALL+VGGFEAY   + L E R +Y E CI MCVIP TISNNVPGT  SLGSDTA+N
Sbjct: 489  IHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAA 548

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
             +  D+IKQSA+GTKRRVFIVETMGGYCGYLAT++ ++ GAD AY+FE+PF + DL  +V
Sbjct: 549  MESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNV 608

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + +  KM+   +R LV+RNE      TT+F+ NL+ SEGK  F  R NVLGH+QQGG+PT
Sbjct: 609  EHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPT 668

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTKL  +A+ +L  +L+E +    +V A +  +A ++GLK + V F+PV +LKK
Sbjct: 669  PFDRNYGTKLGVKAMLWLSEKLRE-VYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKK 727

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 728  DTDFEHRMPREQW 740


>gi|125127|sp|P12382|K6PL_MOUSE 6-phosphofructokinase, liver type
            (Phosphofructokinase 1) (Phosphohexokinase)
            (Phosphofructo-1-kinase isozyme B) (PFK-B)
 gi|109512|pir||A31070 6-phosphofructokinase (EC 2.7.1.11), hepatic -
            mouse
 gi|515965|gb|AAA20076.1| phosphofructokinase
          Length = 780

 Score =  802 bits (2071), Expect = 0.0
 Identities = 406/734 (55%), Positives = 528/734 (71%), Gaps = 1/734 (0%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++TRM IY G KV+L            + IK A W +VS
Sbjct: 15   GKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKPANWLSVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
            +IIQ GGTIIGSAR   F TREGRL AA NL+  GI  L  IGGDGSLTGAN FR EW
Sbjct: 75   NIIQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDGSLTGANIFRNEWGS 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++ELVK  +++ + A+   ++ I GLVGSIDNDFCGTDMTIGTDSAL RI+  IDA+
Sbjct: 135  LLEELVKEGKISESTAQNYAHLTIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+ALAS AD+ FIPE P  + W + +C++L + RS G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIII+AEGAIDR GK I++  VK  V ++L +DTRVT+LGHVQRGG PSAFDR+L
Sbjct: 255  SRLNIIIIAEGAIDRHGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            +MG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ VQKAM ++ +  A+ LR
Sbjct: 315  KMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEERFDEAIQLR 374

Query: 1213 GRSFQRNLETYKLLTKMR-TVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYH 1389
            GRSF+ N + YKLL   + + EK N      F++A++NVGAPA GMNAAV S VR  +
Sbjct: 375  GRSFENNWKIYKLLAHQKVSKEKSN------FSLAILNVGAPAAGMNAAVPSAVRTGISE 428

Query: 1390 QCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKH 1569
              TVY + D FEGLA G  ++  W DV  W   GGS LGT+++LP +  +  +   L+ +
Sbjct: 429  GHTVYIVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLP-KPHLEAIVENLRTY 487

Query: 1570 NIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINE 1749
            NI ALL++GGFEAY   + L E R +Y E CI MCVIP TISNNVPGT  SLGSDTA+N
Sbjct: 488  NIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNA 547

Query: 1750 ICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDD 1929
              +  D+IKQSA+GTKRRVFIVETMGGYCGYLAT++ ++ GAD AY+FE+PF + DL  +
Sbjct: 548  AMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKAN 607

Query: 1930 VDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSP 2109
            V+ +  KM+   +R LV+RNE   ++ TT+F+ NL+ SEG+  F  R NVLGH+QQGG+P
Sbjct: 608  VEHMTEKMKTDIQRGLVLRNEKCHEHYTTEFLYNLYSSEGRGVFDCRTNVLGHLQQGGAP 667

Query: 2110 TPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLK 2289
            TPFDRN GTKL  +A+ ++  +L++ +    +V A +  +A ++GL+ + V F+PV +LK
Sbjct: 668  TPFDRNYGTKLGVKAMLWVSEKLRD-VYRKGRVFANAPDSACVIGLRKKVVAFSPVTELK 726

Query: 2290 KETDFEHRLPSEQW 2331
            KETDFEHR+P EQW
Sbjct: 727  KETDFEHRMPREQW 740


>gi|26345672|dbj|BAC36487.1| unnamed protein product [Mus musculus]
          Length = 784

 Score =  802 bits (2071), Expect = 0.0
 Identities = 409/733 (55%), Positives = 520/733 (70%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++ RM IY G KVY               I EA W+ VS
Sbjct: 23   GKAIGVLTSGGDAQGMNAAVRAVVRMGIYTGAKVYFIYEGYQGLVDGGSNIVEAKWDCVS 82

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             I+Q GGTIIGSAR   FR+REGRLKAA NL   GI  L  IGGDGSLTGAN FR EW+
Sbjct: 83   SILQVGGTIIGSARCKAFRSREGRLKAACNLARLGITNLCVIGGDGSLTGANLFRKEWSG 142

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++EL +N  +     +K  Y+ +VG+VGSIDNDFCGTDMTIGTDSAL RII  +DA++
Sbjct: 143  LLEELARNGDIDNDTVQKYSYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMT 202

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+AL   AD+ F+PE P  E+W + +C KLS+ R+
Sbjct: 203  TAQSHQRTFVLEVMGRHCGYLALVSALTCGADWVFLPESPPEEDWEENMCLKLSENRARK 262

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
            +RLNIIIV+EGAID   K IT+E +K  V + L +DTRVTILGHVQRGG PSAFDR+L
Sbjct: 263  KRLNIIIVSEGAIDMQNKPITSEKIKELVVKNLGFDTRVTILGHVQRGGTPSAFDRILAS 322

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T E+  CV+S+ GN  VR+PL++CV+ TQ VQKAM ++ +  AV LR
Sbjct: 323  RMGVEAVIALLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFKEAVKLR 382

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GR F+ NL TYK L      EK   S     NVAVINVGAPA GMNAAVRS VR+ +
Sbjct: 383  GRRFEGNLNTYKRLAIKLPDEKIVKS---NCNVAVINVGAPAAGMNAAVRSAVRVGIADG 439

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              ++ I D FEG ANG  K+  W+DV  W   GGS LGT+++LP  K + ++A Q+  H+
Sbjct: 440  HKMFAIYDGFEGFANGQIKEIGWADVGGWTGQGGSILGTKRTLP-GKYLEKIAEQMHSHS 498

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I ALL++GGFE YH  I+L+E R  + EFCIP+CV+P TISN++PG+ +S+G DTA+N I
Sbjct: 499  INALLIIGGFEGYHGAIMLSEARNNHEEFCIPICVLPATISNDIPGSDISIGCDTALNVI 558

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
             +  D+IKQSA+GTKRRVFI+ETMGGYCGYLA + AL++GAD AYIFEEPF + DL  +V
Sbjct: 559  VETCDRIKQSASGTKRRVFIIETMGGYCGYLANMGALAAGADAAYIFEEPFDIGDLQSNV 618

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
              +  KM+   +R LV+RNE    N TTDF+  L+  EGK  F  R NVLGH+QQGG+P+
Sbjct: 619  VHLTEKMKTSIQRGLVLRNESCSVNYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPS 678

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTK++A+A+E++  +LK +     K +  S  +  +LG+  R ++F PV +LKK
Sbjct: 679  PFDRNFGTKISAKAMEWISAKLKGSQGTGKKFV--SDDSICVLGICKRDLLFQPVAELKK 736

Query: 2293 ETDFEHRLPSEQW 2331
             TDFEHR+P EQW
Sbjct: 737  VTDFEHRIPKEQW 749


>gi|105155|pir||A33639 6-phosphofructokinase (EC 2.7.1.11), hepatic -
            human
          Length = 780

 Score =  801 bits (2070), Expect = 0.0
 Identities = 406/733 (55%), Positives = 520/733 (70%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD QGMN+AVR++TRM IY G KV+L            + IK+A W +VS
Sbjct: 15   GKAIGVLTSGGDRQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
            +IIQ GGTIIG+AR   F TREGR  AA NL+  GI  L  IGGDGSLTGAN FR EW
Sbjct: 75   NIIQLGGTIIGTARCKAFTTREGRRAAANNLVQHGITNLCVIGGDGSLTGANIFRSEWGS 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++ELV   +++   A    ++ I GLVGSIDNDFCGTDMTIGTDSAL RI+  IDA+
Sbjct: 135  LLEELVAEGKISETTAWTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+ALAS AD+ FIPE P  + W + +C++L + RS G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIII+AEGAIDR+GK I++  VK  V ++L +DTRVT+LGHVQRGG PSAFDR+L
Sbjct: 255  SRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            +MG EAV AL+E T ++  CV+++ GN  VR+PL++CV+ T+ VQKAM DK +  A  LR
Sbjct: 315  KMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLR 374

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            G SF+ N   YKLLT  +  +     E   F++A++NVGAPA GMNAAVRS VR  + H
Sbjct: 375  GGSFENNWNIYKLLTHQKPPK-----EKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHG 429

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
             TVY + D FEGLA G  ++  W DV  W   GGS LGT+++LP +  +  +   ++ +
Sbjct: 430  HTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLP-KGQLESIVENIRIYG 488

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I ALL+VGGFEAY   + L E R +Y E CI MCVIP TISNNVPGT  SLGSDTA+N
Sbjct: 489  IHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAA 548

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
             +  D+IKQSA+GTKRRVFIVETMGGYCGYLAT++ ++ GAD AY+FE+PF + DL  +V
Sbjct: 549  MESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNV 608

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + +  KM+   +R LV+RNE      TT+F+ NL+ SEGK  F  R NVLGH+QQGG+PT
Sbjct: 609  EHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPT 668

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTKL  +A+ +L  +L+E +    +V A +  +A ++GLK + V F+PV +LKK
Sbjct: 669  PFDRNYGTKLGVKAMLWLSEKLRE-VYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKK 727

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 728  DTDFEHRMPREQW 740


>gi|9988057|sp|P17858|K6PL_HUMAN 6-phosphofructokinase, liver type
            (Phosphofructokinase 1) (Phosphohexokinase)
            (Phosphofructo-1-kinase isozyme B) (PFK-B)
          Length = 780

 Score =  801 bits (2068), Expect = 0.0
 Identities = 406/733 (55%), Positives = 520/733 (70%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++TRM IY G KV+L            + IK+A W +VS
Sbjct: 15   GKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
            +IIQ GGTIIGSAR   F TREGR  AA NL+  GI  L  IGGDGSLTGAN FR EW
Sbjct: 75   NIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGS 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++ELV   +++   A    ++ I GLVGSIDNDFCGTDMTIGTDSAL RI+  IDA+
Sbjct: 135  LLEELVAEGKISETTAWTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+ALAS AD+ FIPE P  + W + +C++L + RS G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIII+AEGAIDR+GK I++  VK  V ++L +DTRVT+LGHVQRGG PSAFDR+L
Sbjct: 255  SRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            +MG EAV AL+E T ++  CV+++ GN  VR+PL++CV+ T+ VQKAM DK +  A  LR
Sbjct: 315  KMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLR 374

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            G SF+ N   YKLL   +  +     E   F++A++NVGAPA GMNAAVRS VR  + H
Sbjct: 375  GGSFENNWNIYKLLAHQKPPK-----EKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHG 429

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
             TVY + D FEGLA G  ++  W DV  W   GGS LGT+++LP +  +  +   ++ +
Sbjct: 430  HTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLP-KGQLESIVENIRIYG 488

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I ALL+VGGFEAY   + L E R +Y E CI MCVIP TISNNVPGT  SLGSDTA+N
Sbjct: 489  IHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAA 548

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
             +  D+IKQSA+GTKRRVFIVETMGGYCGYLAT++ ++ GAD AY+FE+PF + DL  +V
Sbjct: 549  MESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNV 608

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + +  KM+   +R LV+RNE      TT+F+ NL+ SEGK  F  R NVLGH+QQGG+PT
Sbjct: 609  EHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPT 668

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTKL  +A+ +L  +L+E +    +V A +  +A ++GLK + V F+PV +LKK
Sbjct: 669  PFDRNYGTKLGVKAMLWLSEKLRE-VYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKK 727

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 728  DTDFEHRMPREQW 740


>gi|14286326|gb|AAH08964.1| Liver phosphofructokinase [Homo sapiens]
 gi|14602832|gb|AAH09919.1| Liver phosphofructokinase [Homo sapiens]
          Length = 780

 Score =  799 bits (2064), Expect = 0.0
 Identities = 404/733 (55%), Positives = 519/733 (70%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++TRM IY G KV+L            + IK+A W +VS
Sbjct: 15   GKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
            +IIQ GGTIIGSAR   F TREGR  AA NL+  GI  L  IGGDGSLTGAN FR EW
Sbjct: 75   NIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGS 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++ELV   +++   A+   ++ I GLVGSIDNDFCGTDMTIGTDSAL RI+  IDA+
Sbjct: 135  LLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+ALAS AD+ FIPE P  + W + +C++L + RS G
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRG 254

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIII+AEGAIDR+GK I++  VK  V ++L +DTRVT+LGHVQRGG PSAFDR+L
Sbjct: 255  SRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSS 314

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            +MG EAV AL+E T ++  CV+++ GN  VR+PL++CV+ T+ VQKAM DK +  A  LR
Sbjct: 315  KMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLR 374

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            G SF+ N   YKLL   +  +     E   F++A++NVGAPA GMNAAVRS VR  + H
Sbjct: 375  GGSFENNWNIYKLLAHQKPPK-----EKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHG 429

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
             TVY + D FEGLA G  ++  W DV  W   GGS LGT+++LP +  +  +   ++ +
Sbjct: 430  HTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLP-KGQLESIVENIRIYG 488

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I ALL+VGGFEAY   + L E R +Y E CI MCVIP TISNNVPGT  SLGSDTA+N
Sbjct: 489  IHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAA 548

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
             +  D+IKQSA+GTKRRVFIVETMGGYCGYLAT++ ++ GAD AY+FE+PF + DL  +V
Sbjct: 549  MESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNV 608

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + +  KM+   +R LV+RNE      TT+F+ NL+ SEG   F  R NVLGH+QQGG+PT
Sbjct: 609  EHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGNGVFDCRTNVLGHLQQGGAPT 668

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTKL  +A+ +L  +L+E +    +V A +  +A ++GLK +   F+PV +LKK
Sbjct: 669  PFDRNYGTKLGVKAMLWLSEKLRE-VYRKGRVFANAPDSACVIGLKKKAAAFSPVTELKK 727

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 728  DTDFEHRMPREQW 740


>gi|5441456|emb|CAB46744.1| pfk_CDS [Homo sapiens]
          Length = 784

 Score =  797 bits (2058), Expect = 0.0
 Identities = 407/737 (55%), Positives = 523/737 (70%), Gaps = 4/737 (0%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD QGMN+AVR++TRM IY G KV+L            + IK+A W +VS
Sbjct: 15   GKAIGVLTSGGDRQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVS 74

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
            +IIQ G TIIG+ARS  F TREGR  AA NL+  GI  L  IGGDGSLTGAN FR EW
Sbjct: 75   NIIQLGATIIGTARSKAFTTREGRRAAANNLVQHGITNLCVIGGDGSLTGANIFRSEWGS 134

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++ELV   +++   A+   ++ I GLVGSIDNDFCGTDMTIGTDSAL RI+  IDA+
Sbjct: 135  LLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITT 194

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWP--AP--ENWRDVLCDKLSQM 840
            TAQSHQR FV+EVMGRHCGYLALV+ALAS AD+ FIPE P  AP  + W + +C++L +
Sbjct: 195  TAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEAPPEDGWENFMCERLGET 254

Query: 841  RSEGQRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDR 1020
            RS G RLNIII+AEGAIDR+GK I++  VK  V ++L +DTRVT+LGHVQRGG PSAFDR
Sbjct: 255  RSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDR 314

Query: 1021 LLGCRMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTA 1200
            +L  +MG EAV AL+E T ++  CV+++ GN  VR+PL++CV+ T+ VQKAM DK +  A
Sbjct: 315  ILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEA 374

Query: 1201 VMLRGRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMA 1380
              LRG SF+ N   Y+LLT  +  +     E   F++A++NVGAPA GMNAAVRS VR
Sbjct: 375  TQLRGGSFENNWNIYRLLTHQKPPK-----EKSNFSLAILNVGAPAAGMNAAVRSAVRTG 429

Query: 1381 LYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQL 1560
            + H  TVY + D FEGLA G  ++  W DV  W   GGS LGT+++LP +  +  +   +
Sbjct: 430  ISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLP-KGQLESIVENI 488

Query: 1561 KKHNIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTA 1740
            + + I ALL+VGGFEAY   + L E R +Y E CI MCVIP TISNNVPGT  SLGSDTA
Sbjct: 489  RIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTA 548

Query: 1741 INEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDL 1920
            +N   +  D+IKQSA+GTKRRVFIVETMGGYCGYLAT++ ++ GAD AY+FE+PF + DL
Sbjct: 549  VNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDL 608

Query: 1921 SDDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQG 2100
              +V+ +  KM+   +R LV+RNE      TT+F+ NL+ SEGK  F  R NVLGH+QQG
Sbjct: 609  KVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQG 668

Query: 2101 GSPTPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQ 2280
            G+PTPFDRN GTKL  +A+ +L  +L+E +    +V A +  +A ++GLK + V F+PV
Sbjct: 669  GAPTPFDRNYGTKLGVKAMLWLSEKLRE-VYRKGRVFANAPDSACVIGLKKKAVAFSPVT 727

Query: 2281 DLKKETDFEHRLPSEQW 2331
            +LKK+TDFEHR+P EQW
Sbjct: 728  ELKKDTDFEHRMPREQW 744


>gi|26347093|dbj|BAC37195.1| unnamed protein product [Mus musculus]
          Length = 784

 Score =  795 bits (2052), Expect = 0.0
 Identities = 408/733 (55%), Positives = 517/733 (69%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++ RM IY G KVY               I EA W+ VS
Sbjct: 23   GKAIGVLTSGGDAQGMNAAVRAVVRMGIYTGAKVYFIYEGYQGLVDGGSNIVEAKWDCVS 82

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             I+Q GGTIIGSAR   FR+REGRLKAA NL   GI  L  IGGDGSLTGAN FR EW+
Sbjct: 83   SILQVGGTIIGSARCKAFRSREGRLKAACNLARLGITNLCVIGGDGSLTGANLFRKEWSG 142

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++EL +N  +     +K  Y+ +VG+VGSIDNDFCGTDMTIGTDSAL RII  +DA++
Sbjct: 143  LLEELARNGDIDNDTVQKYSYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMT 202

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+AL   AD+ F+PE P  E+W + +C KLS+ R+
Sbjct: 203  TAQSHQRTFVLEVMGRHCGYLALVSALTCGADWVFLPESPPEEDWEENMCLKLSENRARK 262

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
            +RLNIIIV+EGAID   K IT+E +K  V + L +DTRVTILGHVQRGG PSAFDR+L
Sbjct: 263  KRLNIIIVSEGAIDMQNKPITSEKIKELVVKNLGFDTRVTILGHVQRGGTPSAFDRILAS 322

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T E+  CV+S+ GN  VR+PL++CV+ TQ VQKAM ++ +  AV LR
Sbjct: 323  RMGVEAVIALLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFKEAVKLR 382

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GR F+ NL TYK L      EK   S     NVAVINVGAPA GMNAAVRS VR+ +
Sbjct: 383  GRRFEGNLNTYKRLAIKLPEEKIVKS---NCNVAVINVGAPAAGMNAAVRSAVRVGIADG 439

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              ++ I D FEG ANG  K+  W+DV  W   GGS LGT+++LP  K + ++A Q+  H+
Sbjct: 440  HKMFAIYDGFEGFANGQIKEIGWADVGGWTGQGGSILGTKRTLP-GKYLEKIAEQMHSHS 498

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I ALL++GGFEAY   + LA  REK+  FC+PM ++P T+SNNVPG+  S+G+DTA+N I
Sbjct: 499  INALLIIGGFEAYLGLLELAAAREKHEAFCVPMVMVPATVSNNVPGSDFSIGADTALNTI 558

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
                D+IKQSA+GTKRRVFI+ETMGGYCGYLA + AL++GAD AYIFEEPF + DL  +V
Sbjct: 559  TDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGALAAGADAAYIFEEPFDIGDLQSNV 618

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
              +  KM+   +R LV+RNE    N TTDF+  L+  EGK  F  R NVLGH+QQGG+P+
Sbjct: 619  VHLTEKMKTSIQRGLVLRNESCSVNYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPS 678

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTK++A+A+E++  +LK +     K +  S  +  +LG+  R ++F PV +LKK
Sbjct: 679  PFDRNFGTKISAKAMEWISAKLKGSQGTGKKFV--SDDSICVLGICKRDLLFQPVAELKK 736

Query: 2293 ETDFEHRLPSEQW 2331
             TDFEHR+P EQW
Sbjct: 737  VTDFEHRIPKEQW 749


>gi|9790051|ref|NP_062677.1| phosphofructokinase, platelet;
            ATP:D-fructose 6-phosphate 1-phosphotransferase [Mus
            musculus]
 gi|13629369|sp|Q9WUA3|K6PP_MOUSE 6-phosphofructokinase, type C
            (Phosphofructokinase 1) (Phosphohexokinase)
            (Phosphofructo-1-kinase isozyme C) (PFK-C)
 gi|4567052|gb|AAD23571.1| phosphofructokinase-1 C isozyme [Mus
            musculus]
 gi|6634465|emb|CAB64347.1| 6-phosphofructokinase; ATP:D-fructose
            6-phosphate 1-phosphotransferase [Mus musculus]
 gi|13905256|gb|AAH06926.1| Phosphofructokinase, platelet [Mus
            musculus]
 gi|26340574|dbj|BAC33949.1| unnamed protein product [Mus musculus]
          Length = 784

 Score =  794 bits (2051), Expect = 0.0
 Identities = 408/733 (55%), Positives = 517/733 (69%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++ RM IY G KVY               I EA W+ VS
Sbjct: 23   GKAIGVLTSGGDAQGMNAAVRAVVRMGIYTGAKVYFIYEGYQGLVDGGSNIVEAKWDCVS 82

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             I+Q GGTIIGSAR   FR+REGRLKAA NL   GI  L  IGGDGSLTGAN FR EW+
Sbjct: 83   SILQVGGTIIGSARCKAFRSREGRLKAACNLARLGITNLCVIGGDGSLTGANLFRKEWSG 142

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++EL +N  +     +K  Y+ +VG+VGSIDNDFCGTDMTIGTDSAL RII  +DA++
Sbjct: 143  LLEELARNGDIDNDTVQKYSYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMT 202

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+AL   AD+ F+PE P  E+W + +C KLS+ R+
Sbjct: 203  TAQSHQRTFVLEVMGRHCGYLALVSALTCGADWVFLPESPPEEDWEENMCLKLSENRARK 262

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
            +RLNIIIV+EGAID   K IT+E +K  V + L +DTRVTILGHVQRGG PSAFDR+L
Sbjct: 263  KRLNIIIVSEGAIDMQNKPITSEKIKELVVKNLGFDTRVTILGHVQRGGTPSAFDRILAS 322

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T E+  CV+S+ GN  VR+PL++CV+ TQ VQKAM ++ +  AV LR
Sbjct: 323  RMGVEAVIALLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFKEAVKLR 382

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GR F+ NL TYK L      EK   S     NVAVINVGAPA GMNAAVRS VR+ +
Sbjct: 383  GRRFEGNLNTYKRLAIKLPDEKIVKS---NCNVAVINVGAPAAGMNAAVRSAVRVGIADG 439

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              ++ I D FEG ANG  K+  W+DV  W   GGS LGT+++LP  K + ++A Q+  H+
Sbjct: 440  HKMFAIYDGFEGFANGQIKEIGWADVGGWTGQGGSILGTKRTLP-GKYLEKIAEQMHSHS 498

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I ALL++GGFEAY   + LA  REK+  FC+PM ++P T+SNNVPG+  S+G+DTA+N I
Sbjct: 499  INALLIIGGFEAYLGLLELAAAREKHEAFCVPMVMVPATVSNNVPGSDFSIGADTALNTI 558

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
                D+IKQSA+GTKRRVFI+ETMGGYCGYLA + AL++GAD AYIFEEPF + DL  +V
Sbjct: 559  TDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGALAAGADAAYIFEEPFDIGDLQSNV 618

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
              +  KM+   +R LV+RNE    N TTDF+  L+  EGK  F  R NVLGH+QQGG+P+
Sbjct: 619  VHLTEKMKTSIQRGLVLRNESCSVNYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPS 678

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTK++A+A+E++  +LK +     K +  S  +  +LG+  R ++F PV +LKK
Sbjct: 679  PFDRNFGTKISAKAMEWISAKLKGSQGTGKKFV--SDDSICVLGICKRDLLFQPVAELKK 736

Query: 2293 ETDFEHRLPSEQW 2331
             TDFEHR+P EQW
Sbjct: 737  VTDFEHRIPKEQW 749


>gi|50414585|gb|AAH77756.1| Unknown (protein for MGC:79063) [Xenopus
            laevis]
          Length = 808

 Score =  794 bits (2050), Expect = 0.0
 Identities = 397/733 (54%), Positives = 525/733 (71%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ +A+ TSGGD+QGMN+AVR++ R+ IY G KVY             D IKEA+W +VS
Sbjct: 44   GKAIAVLTSGGDAQGMNAAVRAVVRVGIYTGAKVYFVHEGYQGLVDGGDNIKEASWESVS 103

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             ++Q GGT+IGSAR  +FR REGRLKAA NL+ +GI  L  IGGDGSLTGA+TFR EW+
Sbjct: 104  MMLQLGGTVIGSARCQDFRGREGRLKAACNLVKKGITNLCVIGGDGSLTGADTFRSEWSG 163

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ +LVK   +T   AKK  Y+ IVGLVGSIDNDFCGTDMTIGTDSAL RI+  +DA+
Sbjct: 164  LLADLVKADTITEDEAKKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITT 223

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV ALA  AD+ F+PE P  ENW + LC +LS+ R  G
Sbjct: 224  TAQSHQRTFVLEVMGRHCGYLALVTALACGADWVFVPESPPEENWEEHLCRRLSETRGRG 283

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIIIVAEGAID  GK IT++ +K  V ++L YDTRVT+LGHVQRGG PSAFDR+LG
Sbjct: 284  SRLNIIIVAEGAIDLHGKPITSDLIKDLVIKRLGYDTRVTVLGHVQRGGTPSAFDRILGS 343

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S+ GN  +R+PL++CV+ T+ V +AM +K +  A+ LR
Sbjct: 344  RMGVEAVMALLEGTPDTPACVVSLSGNQAIRLPLMECVQVTKEVTQAMNEKKFEEALKLR 403

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            G+SF+ N + Y+ L  +R       S    +N+AV+NVGAPA GMNAAVRS VR+ +
Sbjct: 404  GKSFENNWKVYRTLAHIRPP-----SAKSGYNLAVLNVGAPAAGMNAAVRSTVRIGIIQG 458

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              ++ + D FEGLA G  ++  WS V  W   GGS LGT+++LP +K   +++  +  +N
Sbjct: 459  HRMFAVHDGFEGLAKGQIEEIGWSGVGGWTGQGGSRLGTKRTLP-KKYFEEISNNISNYN 517

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I  L++VGGFEA+  ++ L E R KY E CIP+ VIP T+SNNVPG+  S+G+DTA+N I
Sbjct: 518  IHGLIIVGGFEAFTGSLELMEGRCKYEELCIPIVVIPATVSNNVPGSDFSIGADTALNTI 577

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
                D+IKQSA GTKRRVFI+ETMGGYCGYLAT++  ++GAD AYI+EE   + +L  +V
Sbjct: 578  TVTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGFAAGADAAYIYEESVNIHELQTNV 637

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + +  KM+   KR L++RNE  + N +TDF+ NL+  EGK  F  R NVLGH+QQGG+PT
Sbjct: 638  EHLTEKMKTTVKRGLILRNEKCNDNYSTDFIFNLYSEEGKGVFDCRKNVLGHMQQGGTPT 697

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTK+ A+A+ ++  ++KE  +   ++ A +  +A LLG++ R +VF P+ +LK+
Sbjct: 698  PFDRNFGTKMGAKAVLWMTGKVKE-CSRHGRIFANTPDSACLLGMRKRSLVFQPLVELKE 756

Query: 2293 ETDFEHRLPSEQW 2331
            +TDF HRLP EQW
Sbjct: 757  QTDFAHRLPKEQW 769


>gi|8489537|gb|AAF75700.1| phosphofructokinase-1 C isozyme [Mus
            musculus]
          Length = 784

 Score =  792 bits (2045), Expect = 0.0
 Identities = 407/733 (55%), Positives = 516/733 (69%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ + + TSGGD+QGMN+AVR++ RM IY G KVY               I EA W+ VS
Sbjct: 23   GKAIGVLTSGGDAQGMNAAVRAVVRMGIYTGAKVYFIYEGYQGLVDGGSNIVEAKWDCVS 82

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             I+Q GGTIIGSAR   FR+REGRLKAA NL   GI  L  IGGDGSLTGAN FR EW+
Sbjct: 83   SILQVGGTIIGSARCKAFRSREGRLKAACNLARLGITNLCVIGGDGSLTGANLFRKEWSG 142

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++EL +N  +     +K  Y+ +VG+VGSIDNDFCG DMTIGTDSAL RII  +DA++
Sbjct: 143  LLEELARNGDIDNDTVQKYSYLNVVGMVGSIDNDFCGPDMTIGTDSALHRIIEVVDAIMT 202

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV+AL   AD+ F+PE P  E+W + +C KLS+ R+
Sbjct: 203  TAQSHQRTFVLEVMGRHCGYLALVSALTCGADWVFLPESPPEEDWEENMCLKLSENRARK 262

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
            +RLNIIIV+EGAID   K IT+E +K  V + L +DTRVTILGHVQRGG PSAFDR+L
Sbjct: 263  KRLNIIIVSEGAIDMQNKPITSEKIKELVVKNLGFDTRVTILGHVQRGGTPSAFDRILAS 322

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T E+  CV+S+ GN  VR+PL++CV+ TQ VQKAM ++ +  AV LR
Sbjct: 323  RMGVEAVIALLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFKEAVKLR 382

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GR F+ NL TYK L      EK   S     NVAVINVGAPA GMNAAVRS VR+ +
Sbjct: 383  GRRFEGNLNTYKRLAIKLPDEKIVKS---NCNVAVINVGAPAAGMNAAVRSAVRVGIADG 439

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              ++ I D FEG ANG  K+  W+DV  W   GGS LGT+++LP  K + ++A Q+  H+
Sbjct: 440  HKMFAIYDGFEGFANGQIKEIGWADVGGWTGQGGSILGTKRTLP-GKYLEKIAEQMHSHS 498

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I ALL++GGFEAY   + LA  REK+  FC+PM ++P T+SNNVPG+  S+G+DTA+N I
Sbjct: 499  INALLIIGGFEAYLGLLELAAAREKHEAFCVPMVMVPATVSNNVPGSDFSIGADTALNTI 558

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
                D+IKQSA+GTKRRVFI+ETMGGYCGYLA + AL++GAD AYIFEEPF + DL  +V
Sbjct: 559  TDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGALAAGADAAYIFEEPFDIGDLQSNV 618

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
              +  KM+   +R LV+RNE    N TTDF+  L+  EGK  F  R NVLGH+QQGG+P+
Sbjct: 619  VHLTEKMKTSIQRGLVLRNESCSVNYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPS 678

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTK++A+A+E++  +LK +     K +  S  +  +LG+  R ++F PV +LKK
Sbjct: 679  PFDRNFGTKISAKAMEWISAKLKGSQGTGKKFV--SDDSICVLGICKRDLLFQPVAELKK 736

Query: 2293 ETDFEHRLPSEQW 2331
             TDFEHR+P EQW
Sbjct: 737  VTDFEHRIPKEQW 749


>gi|45383682|ref|NP_989554.1| liver phosphofructokinase [Gallus
            gallus]
 gi|16610202|dbj|BAB71763.1| 6-phosphofructokinase [Gallus gallus]
          Length = 769

 Score =  790 bits (2041), Expect = 0.0
 Identities = 406/740 (54%), Positives = 527/740 (70%), Gaps = 7/740 (0%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ +A+ TSGGD+QGMN+AVR++ R+ IY G KVY             D +KEATW +VS
Sbjct: 4    GKAIAVLTSGGDAQGMNAAVRAVVRVGIYTGAKVYFVHEGYQGLVDGGDNLKEATWESVS 63

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             ++Q GGT+IGSAR  +FRTREGRLKAA NL+ RGI  L  IGGDGSLTGA+TFR EW+
Sbjct: 64   MMLQLGGTVIGSARCQDFRTREGRLKAARNLVKRGITNLCVIGGDGSLTGADTFRAEWSS 123

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ EL+K   +TA  AKK  ++ IVG+VGSIDNDFCGTDMTIGTDSAL RI+  +DA+
Sbjct: 124  LLAELLKTGGITAEEAKKSSHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITT 183

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLAL+ +LA  AD+ FIPE P  + W D LC + ++ R  G
Sbjct: 184  TAQSHQRTFVLEVMGRHCGYLALITSLACGADWVFIPESPPEDGWEDHLC-RPTETRLGG 242

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIIIVAEGAIDR GKAIT++DVK  V ++L YDTRVTILGHVQRGG PSAFDR+LG
Sbjct: 243  SRLNIIIVAEGAIDRHGKAITSDDVKDLVVKRLGYDTRVTILGHVQRGGTPSAFDRILGS 302

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ V  AM ++ +  AV LR
Sbjct: 303  RMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTTAMNERRFDDAVKLR 362

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSFQ N   YKLL  +R     +   GH   +AV+NVGAPA GMNAAVRS VR+ L H
Sbjct: 363  GRSFQNNWNVYKLLAHIR---PPSTKSGH--TLAVLNVGAPAAGMNAAVRSTVRIGLIHG 417

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              +  + D FEGLA G  +   W  V  W   GGS LGT+++LP +K   +++A +
Sbjct: 418  HRMLAVHDGFEGLALGKVEDISWDMVGGWTGLGGSKLGTKRTLP-KKYFEEISATISTFG 476

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I  L+++GGFEA+  ++ L + R K+ E CIP+CVIP T+SNNVPG+  S+G+DTA+N I
Sbjct: 477  IHGLIIIGGFEAFMGSLELMDGRAKFEELCIPICVIPATVSNNVPGSDFSIGADTALNTI 536

Query: 1753 CQMIDKIKQSATGTKRRVFIVETM-------GGYCGYLATLSALSSGADNAYIFEEPFTV 1911
                D+IKQSA GTKRRVFI+ETM       GGYCGYLA      +GAD AYIFEE F++
Sbjct: 537  TTTCDRIKQSAAGTKRRVFIIETMGTWPPWQGGYCGYLA------AGADAAYIFEEHFSI 590

Query: 1912 QDLSDDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHV 2091
            +DL  +V+ +  KM+   KR LV+RNE  ++N TTDF+ NL+  EGK  F  R NVLGH+
Sbjct: 591  RDLQINVEHLTEKMKTTVKRGLVLRNEHCNENYTTDFIYNLYTEEGKGIFDCRKNVLGHM 650

Query: 2092 QQGGSPTPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFT 2271
            QQGG+PTPFDRN GTK+ A+++ ++  ++KE  +   ++ A +A +A LLG++ R +VF
Sbjct: 651  QQGGAPTPFDRNFGTKMGAKSVAWITGKIKE-CSRHGRIFANTADSACLLGMRKRSLVFQ 709

Query: 2272 PVQDLKKETDFEHRLPSEQW 2331
            P+ +LK++TDF+HR+P EQW
Sbjct: 710  PLTELKEQTDFQHRIPKEQW 729


>gi|1346357|sp|P47860|K6PP_RAT 6-phosphofructokinase, type C
            (Phosphofructokinase 1) (Phosphohexokinase)
            (Phosphofructo-1-kinase isozyme C) (PFK-C)
          Length = 786

 Score =  786 bits (2029), Expect = 0.0
 Identities = 399/733 (54%), Positives = 514/733 (69%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+   + TSGG+SQGMN+AVR++ RM +Y G +VY               I EA W  VS
Sbjct: 22   GKAXGVLTSGGESQGMNAAVRAVVRMGMYTGAQVYFIYEGYQGMVDGGSNIVEAKWECVS 81

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             I+Q GGTIIGSAR   FR+REGRLKA  NL+  GI  L  IGGDGSLTGAN FR EW+
Sbjct: 82   SILQVGGTIIGSARCQAFRSREGRLKATCNLVRLGITNLCVIGGDGSLTGANLFRKEWSG 141

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L++EL KN  + +   KK  Y+ +VG+VGSIDNDFCGTDMTIGTDSAL RII  +DA++
Sbjct: 142  LLEELAKNGEIDSDTVKKHAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMT 201

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGR+CGYLALV+ALA  AD+ F+PE P  E W + +C KLS+ R+
Sbjct: 202  TAQSHQRTFVLEVMGRYCGYLALVSALACGADWVFLPESPPEEGWEEEMCLKLSENRARK 261

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
            +RLNIIIV+EGAID   K IT+E +K  V   L +DTRVTILGHVQRGG PSAFDR+L
Sbjct: 262  KRLNIIIVSEGAIDTQNKPITSEKIKELVVTNLGFDTRVTILGHVQRGGTPSAFDRILAS 321

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T E+  CV+S+ GN  VR+PL++CV+ TQ VQKAM ++ +  AV LR
Sbjct: 322  RMGVEAVLALLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFDEAVKLR 381

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF+ NL TYK   ++   E D+       NVA+INVGAPA GMNAAVRS VR+ +
Sbjct: 382  GRSFEGNLNTYK---RLAIKEPDDKIPKSNCNVAIINVGAPAAGMNAAVRSAVRVGIAEG 438

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              ++ I D F+GLANG  K+  W DV  W   GGS LGT+++LP  K + ++A Q+   N
Sbjct: 439  HKMFAIYDGFDGLANGQIKEIGWGDVGGWTGQGGSILGTKRTLP-GKYLEKIAEQMHSKN 497

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            I ALL++GGFEAY   + LA  R K+  FC+PM ++P T+SNNVPG+  S+G+DTA+N I
Sbjct: 498  INALLIIGGFEAYLGLLELAAARNKHEAFCVPMVMVPATVSNNVPGSDFSIGADTALNTI 557

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
                D+IKQSA+GTKRRVFI+ETMGGYCGYLA +  L++G D AYIFEE F ++DL  +V
Sbjct: 558  TDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGRDAAYIFEEQFDIRDLQSNV 617

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
              +  KM+   +R LV+RNE    N TTDF+  L+  EGK  F  R NVLGH+QQGG+P+
Sbjct: 618  MHLTEKMKTSIQRGLVLRNENCSVNYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPS 677

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN GTK++A+A+E++  +LK +     K +  S  +  +LG++ R ++F PV +L+K
Sbjct: 678  PFDRNFGTKISAKAMEWISAKLKGSHGTGKKFV--SDDSICVLGIQKRDLLFKPVAELRK 735

Query: 2293 ETDFEHRLPSEQW 2331
             TDFEHR+P +QW
Sbjct: 736  ATDFEHRIPKQQW 748


>gi|50346005|ref|NP_001002021.1| liver phosphofructokinase isoform a;
            6-phosphofructokinase, liver type; liver-type
            1-phosphofructokinase; phosphofructokinase 1;
            phosphohexokinase; phosphofructo-1-kinase isozyme B [Homo
            sapiens]
 gi|13623609|gb|AAH06422.1| Liver phosphofructokinase, isoform a [Homo
            sapiens]
          Length = 827

 Score =  785 bits (2028), Expect = 0.0
 Identities = 399/719 (55%), Positives = 510/719 (70%)
 Frame = +1

Query: 175  GMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVSDIIQQGGTIIGSAR 354
            GMN+AVR++TRM IY G KV+L            + IK+A W +VS+IIQ GGTIIGSAR
Sbjct: 76   GMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSAR 135

Query: 355  SSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAA 534
               F TREGR  AA NL+  GI  L  IGGDGSLTGAN FR EW  L++ELV   +++
Sbjct: 136  CKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISET 195

Query: 535  AAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVM 714
             A+   ++ I GLVGSIDNDFCGTDMTIGTDSAL RI+  IDA+  TAQSHQR FV+EVM
Sbjct: 196  TARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVM 255

Query: 715  GRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAID 894
            GRHCGYLALV+ALAS AD+ FIPE P  + W + +C++L + RS G RLNIII+AEGAID
Sbjct: 256  GRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAID 315

Query: 895  RDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMT 1074
            R+GK I++  VK  V ++L +DTRVT+LGHVQRGG PSAFDR+L  +MG EAV AL+E T
Sbjct: 316  RNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEAT 375

Query: 1075 EESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLL 1254
             ++  CV+++ GN  VR+PL++CV+ T+ VQKAM DK +  A  LRG SF+ N   YKLL
Sbjct: 376  PDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLL 435

Query: 1255 TKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLA 1434
               +  +     E   F++A++NVGAPA GMNAAVRS VR  + H  TVY + D FEGLA
Sbjct: 436  AHQKPPK-----EKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLA 490

Query: 1435 NGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHNIQALLLVGGFEAYH 1614
             G  ++  W DV  W   GGS LGT+++LP +  +  +   ++ + I ALL+VGGFEAY
Sbjct: 491  KGQVQEVGWHDVAGWLGRGGSMLGTKRTLP-KGQLESIVENIRIYGIHALLVVGGFEAYE 549

Query: 1615 STIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGT 1794
              + L E R +Y E CI MCVIP TISNNVPGT  SLGSDTA+N   +  D+IKQSA+GT
Sbjct: 550  GVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGT 609

Query: 1795 KRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRY 1974
            KRRVFIVETMGGYCGYLAT++ ++ GAD AY+FE+PF + DL  +V+ +  KM+   +R
Sbjct: 610  KRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRG 669

Query: 1975 LVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARA 2154
            LV+RNE      TT+F+ NL+ SEGK  F  R NVLGH+QQGG+PTPFDRN GTKL  +A
Sbjct: 670  LVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKA 729

Query: 2155 LEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKKETDFEHRLPSEQW 2331
            + +L  +L+E +    +V A +  +A ++GLK + V F+PV +LKK+TDFEHR+P EQW
Sbjct: 730  MLWLSEKLRE-VYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQW 787



 Score =  129 bits (325), Expect = 2e-28
 Identities = 99/303 (32%), Positives = 163/303 (53%), Gaps = 26/303 (8%)
 Frame = +1

Query: 1339 GGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANG--SFKQFKWSDVTNWAMNGGSFLGTQ 1512
            GGMNAAVR+  RM +Y    V+ I + +EGL  G  + KQ  W  V+N    GG+ +G+
Sbjct: 75   GGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSA 134

Query: 1513 --KSLPTEKTMPQLAAQLKKHNIQALLLVGG---------FEAYHSTI---ILAENR--- 1641
              K+  T +     A  L +H I  L ++GG         F +   ++   ++AE +
Sbjct: 135  RCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISE 194

Query: 1642 ---EKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKRRVFI 1812
                 Y    I   V   +I N+  GT +++G+D+A++ I ++ID I  +A  + +R F+
Sbjct: 195  TTARTYSHLNIAGLV--GSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQ-SHQRTFV 251

Query: 1813 VETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLVVRNE 1992
            +E MG +CGYLA +SAL+SGAD  +I E P      +   + +      G++  +++  E
Sbjct: 252  LEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAE 311

Query: 1993 WA-DKN---LTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALE 2160
             A D+N   +++ +V++L     +  F TRV VLGHVQ+GG+P+ FDR + +K+   A+
Sbjct: 312  GAIDRNGKPISSSYVKDLVVQ--RLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVM 369

Query: 2161 FLL 2169
             LL
Sbjct: 370  ALL 372



 Score =  112 bits (280), Expect = 4e-23
 Identities = 97/344 (28%), Positives = 163/344 (47%), Gaps = 8/344 (2%)
 Frame = +1

Query: 139  TLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVSDI 318
            +LAI   G  + GMN+AVRS  R  I  G  VY+              ++E  W+ V+
Sbjct: 448  SLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQ--VQEVGWHDVAGW 505

Query: 319  IQQGGTIIGSARSSEFRTREGRLKA-ATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDL 495
            + +GG+++G+ R+      +G+L++   N+   GI  L+ +GG  +  G
Sbjct: 506  LGRGGSMLGTKRT----LPKGQLESIVENIRIYGIHALLVVGGFEAYEGV---------- 551

Query: 496  VQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVAT 675
                   Q V A    +   I +  +  +I N+  GTD ++G+D+A+   + S D +  +
Sbjct: 552  ------LQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQS 605

Query: 676  AQ-SHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQ-MRSE 849
            A  + +R F++E MG +CGYLA V  +A  AD  ++ E P   +   V  + +++ M+++
Sbjct: 606  ASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTD 665

Query: 850  GQRLNIIIVAEGAIDRDGKA---ITAEDVKTAVKEKLK--YDTRVTILGHVQRGGAPSAF 1014
             QR        G + R+ K     T E +      + K  +D R  +LGH+Q+GGAP+ F
Sbjct: 666  IQR--------GLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPF 717

Query: 1015 DRLLGCRMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCV 1146
            DR  G ++G +A+  L E   E     +   G V    P   CV
Sbjct: 718  DRNYGTKLGVKAMLWLSEKLRE-----VYRKGRVFANAPDSACV 756


>gi|1083579|pir||A53047 6-phosphofructokinase (EC 2.7.1.11) - rat
 gi|473914|gb|AAA17757.1| phosphofructokinase C [Rattus sp.]
          Length = 765

 Score =  783 bits (2022), Expect = 0.0
 Identities = 398/728 (54%), Positives = 512/728 (69%)
 Frame = +1

Query: 148  IYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVSDIIQQ 327
            + TSGG+SQGMN+AVR++ RM +Y G +VY               I EA W  VS I+Q
Sbjct: 6    VLTSGGESQGMNAAVRAVVRMGMYTGAQVYFIYEGYQGMVDGGSNIVEAKWECVSSILQV 65

Query: 328  GGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQEL 507
            GGTIIGSAR   FR+REGRLKA  NL+  GI  L  IGGDGSLTGAN FR EW+ L++EL
Sbjct: 66   GGTIIGSARCQAFRSREGRLKATCNLVRLGITNLCVIGGDGSLTGANLFRKEWSGLLEEL 125

Query: 508  VKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSH 687
             KN  + +   KK  Y+ +VG+VGSIDNDFCGTDMTIGTDSAL RII  +DA++ TAQSH
Sbjct: 126  AKNGEIDSDTVKKHAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSH 185

Query: 688  QRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNI 867
            QR FV+EVMGR+CGYLALV+ALA  AD+ F+PE P  E W + +C KLS+ R+  +RLNI
Sbjct: 186  QRTFVLEVMGRYCGYLALVSALACGADWVFLPESPPEEGWEEEMCLKLSENRARKKRLNI 245

Query: 868  IIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAE 1047
            IIV+EGAID   K IT+E +K  V   L +DTRVTILGHVQRGG PSAFDR+L  RMG E
Sbjct: 246  IIVSEGAIDTQNKPITSEKIKELVVTNLGFDTRVTILGHVQRGGTPSAFDRILASRMGVE 305

Query: 1048 AVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGRSFQ 1227
            AV AL+E T E+  CV+S+ GN  VR+PL++CV+ TQ VQKAM ++ +  AV LRGRSF+
Sbjct: 306  AVLALLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFDEAVKLRGRSFE 365

Query: 1228 RNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQCTVYG 1407
             NL TYK   ++   E D+       NVA+INVGAPA GMNAAVRS VR+ +     ++
Sbjct: 366  GNLNTYK---RLAIKEPDDKIPKSNCNVAIINVGAPAAGMNAAVRSAVRVGIAEGHKMFA 422

Query: 1408 IEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHNIQALL 1587
            I D F+GLANG  K+  W DV  W   GGS LGT+++LP  K + ++A Q+   NI ALL
Sbjct: 423  IYDGFDGLANGQIKEIGWGDVGGWTGQGGSILGTKRTLP-GKYLEKIAEQMHSKNINALL 481

Query: 1588 LVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEICQMID 1767
            ++GGFEAY   + LA  R K+  FC+PM ++P T+SNNVPG+  S+G+DTA+N I    D
Sbjct: 482  IIGGFEAYLGLLELAAARNKHEAFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCD 541

Query: 1768 KIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDVILS 1947
            +IKQSA+GTKRRVFI+ETMGGYCGYLA +  L++G D AYIFEE F ++DL  +V  +
Sbjct: 542  RIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGRDAAYIFEEQFDIRDLQSNVMHLTE 601

Query: 1948 KMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPFDRN 2127
            KM+   +R LV+RNE    N TTDF+  L+  EGK  F  R NVLGH+QQGG+P+PFDRN
Sbjct: 602  KMKTSIQRGLVLRNENCSVNYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRN 661

Query: 2128 MGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKKETDFE 2307
             GTK++A+A+E++  +LK +     K +  S  +  +LG++ R ++F PV +L+K TDFE
Sbjct: 662  FGTKISAKAMEWISAKLKGSHGTGKKFV--SDDSICVLGIQKRDLLFKPVAELRKATDFE 719

Query: 2308 HRLPSEQW 2331
            HR+P +QW
Sbjct: 720  HRIPKQQW 727



 Score =  105 bits (263), Expect = 4e-21
 Identities = 102/350 (29%), Positives = 162/350 (46%), Gaps = 20/350 (5%)
 Frame = +1

Query: 64   RRFDSIVPTAGR--EGT----------EIASDIFKGR-TLAIYTSGGDSQGMNSAVRSIT 204
            RRFD  V   GR  EG           E    I K    +AI   G  + GMN+AVRS
Sbjct: 351  RRFDEAVKLRGRSFEGNLNTYKRLAIKEPDDKIPKSNCNVAIINVGAPAAGMNAAVRSAV 410

Query: 205  RMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVSDIIQQGGTIIGSARSSEFRTREGR 384
            R+ I  G K++               IKE  W  V     QGG+I+G+ R+   +  E
Sbjct: 411  RVGIAEGHKMFAIYDGFDGLANGQ--IKEIGWGDVGGWTGQGGSILGTKRTLPGKYLE-- 466

Query: 385  LKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAAAKKIPY-IQ 561
             K A  + ++ I  L+ IGG  +  G                    + AA  K   + +
Sbjct: 467  -KIAEQMHSKNINALLIIGGFEAYLGL-----------------LELAAARNKHEAFCVP 508

Query: 562  IVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQ-SHQRAFVIEVMGRHCGYLA 738
            +V +  ++ N+  G+D +IG D+AL  I  + D +  +A  + +R F+IE MG +CGYLA
Sbjct: 509  MVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLA 568

Query: 739  LVAALASEADFCFIPEWPAPENWRDVLCDKL---SQMRSEGQRLNIIIVAEGAIDRDGKA 909
             +  LA+  D  +I E     + RD+  + +    +M++  QR  ++     +++
Sbjct: 569  NMGGLAAGRDAAYIFE--EQFDIRDLQSNVMHLTEKMKTSIQRGLVLRNENCSVN----- 621

Query: 910  ITAEDVKTAVKEKLK--YDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAV 1053
             T + +     E+ K  +D R  +LGH+Q+GGAPS FDR  G ++ A+A+
Sbjct: 622  YTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISAKAM 671


>gi|3122305|sp|Q27778|K6PF_SCHMA 6-phosphofructokinase
            (Phosphofructokinase) (Phosphohexokinase)
 gi|533268|gb|AAA29911.1| phosphofructokinase
          Length = 781

 Score =  780 bits (2014), Expect = 0.0
 Identities = 397/750 (52%), Positives = 516/750 (67%), Gaps = 6/750 (0%)
 Frame = +1

Query: 100  EGTEIASDIFKGRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXD 279
            EG  +A   F G  +A+ TSGGD+QGMN+AVR++ RM IYCGC+V+
Sbjct: 6    EGKYVARGQFTGECIAVLTSGGDAQGMNAAVRAVVRMGIYCGCRVFFIREGYQGLVDGGQ 65

Query: 280  FIKEATWNTVSDIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLT 459
             I+EA+W  VS I+Q GGT IGSAR  +FR R GRLKAA NL+   I  LV IGGDGSLT
Sbjct: 66   NIQEASWADVSGILQLGGTKIGSARCMDFRERYGRLKAAENLVKNQITNLVVIGGDGSLT 125

Query: 460  GANTFRLEWTDLVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQ 639
            GAN FR EW+ L++ELV + +++A +AK+   + IVGLVGSIDNDFCGTDMTIG DSAL
Sbjct: 126  GANLFRAEWSSLLEELVTSNKISAESAKQFHRLNIVGLVGSIDNDFCGTDMTIGADSALH 185

Query: 640  RIISSIDAVVATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVL 819
            RII + DA+  TA SHQR F++EVMGRHCGYLALVA++A EAD+ FIPE P  ++WR+ L
Sbjct: 186  RIIEATDAISTTAHSHQRCFILEVMGRHCGYLALVASMACEADWVFIPEMPPTDDWREKL 245

Query: 820  CDKLSQMRSEGQRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGG 999
            C KL   R  GQR+NII+VAEGAIDR  K IT E VK  +  +L+ DTR+T+LGHVQRGG
Sbjct: 246  CHKLRMNREHGQRVNIIMVAEGAIDRACKPITCEIVKNLIVSELQLDTRITVLGHVQRGG 305

Query: 1000 APSAFDRLLGCRMGAEAVFALMEMTEESE--PCVISIDGNVMVRVPLLKCVERTQMVQKA 1173
            +PSAFDR+LG RMGAEAV ALM+   +     CVIS+DGN  VRVPL+KCV+RT+ V +A
Sbjct: 306  SPSAFDRILGSRMGAEAVLALMDADRDPNLPSCVISLDGNQAVRVPLVKCVDRTRQVAEA 365

Query: 1174 MADKDWTTAVMLRGRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNA 1353
            M   D+  AV LRG SF  NL TY  L+K+    +  +S  +   + ++NVGAPA G+NA
Sbjct: 366  MKACDFDHAVELRGTSFMNNLATYIKLSKIEQPRQSVMSSENNLRIGIVNVGAPACGINA 425

Query: 1354 AVRSYVRMALYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEK 1533
             +R + R+ +     V GI + F GL  G   + +W+DV  W   GGS LGT++  P
Sbjct: 426  VIRGFTRLGITKGYKVIGIHEGFSGLVKGDASEIQWADVRGWVGMGGSMLGTRRDTPNGL 485

Query: 1534 TMPQLAAQLKKHNIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGT 1713
             + ++AA+ K+  +  LL++GGFEAY   I L E REKYPE CIPM ++P TISNNVPGT
Sbjct: 486  GIDKVAAKFKELKLSGLLIIGGFEAYECMIELVEGREKYPELCIPMAMVPATISNNVPGT 545

Query: 1714 MVSLGSDTAINEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIF 1893
              SLG DTA+NEI  ++DKIKQSA GTKRRVF+VETMGGYCGYLAT+SAL+ GAD AYIF
Sbjct: 546  DFSLGCDTALNEITSVLDKIKQSALGTKRRVFVVETMGGYCGYLATMSALAGGADAAYIF 605

Query: 1894 EEPFTVQDLSDDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRV 2073
            EEPFT+ DL +DV  + +K++   KR LV+R +     +T++F+  L+  EG+  F  R
Sbjct: 606  EEPFTIDDLREDVVHLRAKIDDNVKRGLVLRADMLINTITSEFIHQLYAQEGQGIFDCRC 665

Query: 2074 NVLGHVQQGGSPTPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLK- 2250
            NVLGH+QQG  P+PFDR++GTK A++A+++L  Q+  N+      I +S H   +L +
Sbjct: 666  NVLGHMQQGDRPSPFDRSLGTKFASKAIDWLDEQINANIVQ----ILQSIHQTFMLYINW 721

Query: 2251 ---GRKVVFTPVQDLKKETDFEHRLPSEQW 2331
                   +F    +L++ TDF HRLP E+W
Sbjct: 722  YCTSSDNLFKYSLELREHTDFVHRLPKEEW 751


>gi|39644779|gb|AAH07798.2| PFKM protein [Homo sapiens]
          Length = 747

 Score =  760 bits (1963), Expect = 0.0
 Identities = 388/733 (52%), Positives = 511/733 (68%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            G+ +A+ TSGGD+QGMN+AVR++ R+ I+ G +V+             D IKEATW +VS
Sbjct: 13   GKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVS 72

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             ++Q GGT+IGSAR  +FR REGRL+AA NL+ RGI  L  IGGDGSLTGA+TFR EW+D
Sbjct: 73   MMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSD 132

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ +L K  ++T   A K  Y+ IVGLVGSIDNDFCGTDMTIGTDSAL RI+  +DA+
Sbjct: 133  LLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITT 192

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR FV+EVMGRHCGYLALV +L+  AD+ FIPE P  ++W + LC +LS+ R+ G
Sbjct: 193  TAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRG 252

Query: 853  QRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGC 1032
             RLNIIIVAEGAID++GK IT+ED+K                                G
Sbjct: 253  SRLNIIIVAEGAIDKNGKPITSEDIKN-------------------------------GS 281

Query: 1033 RMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLR 1212
            RMG EAV AL+E T ++  CV+S+ GN  VR+PL++CV+ T+ V KAM +K +  A+ LR
Sbjct: 282  RMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLR 341

Query: 1213 GRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQ 1392
            GRSF  N E YKLL  +R      +S+     VAV+NVGAPA GMNAAVRS VR+ L
Sbjct: 342  GRSFMNNWEVYKLLAHVRPP----VSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQG 397

Query: 1393 CTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHN 1572
              V  + D FEGLA G  ++  WS V  W   GGS LGT+++LP +K+  Q++A + K N
Sbjct: 398  NRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLP-KKSFEQISANITKFN 456

Query: 1573 IQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTAINEI 1752
            IQ L+++GGFEAY   + L E R+++ E CIP  VIP T+SNNVPG+  S+G+DTA+N I
Sbjct: 457  IQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTI 516

Query: 1753 CQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDV 1932
            C   D+IKQSA GTKRRVFI+ETMGGYCGYLAT++ L++GAD AYIFEEPFT++DL  +V
Sbjct: 517  CTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQANV 576

Query: 1933 DVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPT 2112
            + ++ KM+   KR LV+RNE  ++N TTDF+ NL+  EGK  F +R NVLGH+QQGGSPT
Sbjct: 577  EHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPT 636

Query: 2113 PFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKK 2292
            PFDRN  TK+ A+A+ ++  ++KE+   + ++ A +  +  +LG++ R +VF PV +LK
Sbjct: 637  PFDRNFATKMGAKAMNWMSGKIKESY-RNGRIFANTPDSGCVLGMRKRALVFQPVAELKD 695

Query: 2293 ETDFEHRLPSEQW 2331
            +TDFEHR+P EQW
Sbjct: 696  QTDFEHRIPKEQW 708



 Score =  117 bits (293), Expect = 1e-24
 Identities = 98/366 (26%), Positives = 171/366 (45%), Gaps = 15/366 (4%)
 Frame = +1

Query: 139  TLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVSDI 318
            T+A+   G  + GMN+AVRS  R+ +  G +V +              I+EA W+ V
Sbjct: 369  TVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQ--IEEAGWSYVGGW 426

Query: 319  IQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLV 498
              QGG+ +G+ R+   ++ E   + + N+    I  LV IGG  + TG     +E
Sbjct: 427  TGQGGSKLGTKRTLPKKSFE---QISANITKFNIQGLVIIGGFEAYTGGLEL-MEGRKQF 482

Query: 499  QELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATA 678
             EL             IP++ I     ++ N+  G+D ++G D+AL  I ++ D +  +A
Sbjct: 483  DELC------------IPFVVIPA---TVSNNVPGSDFSVGADTALNTICTTCDRIKQSA 527

Query: 679  Q-SHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQ 855
              + +R F+IE MG +CGYLA +A LA+ AD  +I E P          + L Q
Sbjct: 528  AGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQANVEHLVQKMKTTV 587

Query: 856  RLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLK--YDTRVTILGHVQRGGAPSAFDRLLG 1029
            +  +++  E    +  +  T + +     E+ K  +D+R  +LGH+Q+GG+P+ FDR
Sbjct: 588  KRGLVLRNE----KCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFDRNFA 643

Query: 1030 CRMGAEAVFALMEMTEES------------EPCVISIDGNVMVRVPLLKCVERTQMVQKA 1173
             +MGA+A+  +    +ES              CV+ +    +V  P+ +  ++T    +
Sbjct: 644  TKMGAKAMNWMSGKIKESYRNGRIFANTPDSGCVLGMRKRALVFQPVAELKDQTDFEHRI 703

Query: 1174 MADKDW 1191
              ++ W
Sbjct: 704  PKEQWW 709


>gi|47226320|emb|CAG09288.1| unnamed protein product [Tetraodon
            nigroviridis]
          Length = 765

 Score =  746 bits (1925), Expect = 0.0
 Identities = 388/724 (53%), Positives = 496/724 (67%), Gaps = 39/724 (5%)
 Frame = +1

Query: 277  DFIKEATWNTVSDIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSL 456
            D IK A W++V++IIQQGGT+IG+AR   F TR+GRL AA NL+ +GI  L   GGDGSL
Sbjct: 16   DNIKLAHWHSVTNIIQQGGTMIGTARCKAFTTRDGRLAAAFNLVKKGITNLCVCGGDGSL 75

Query: 457  TGANTFRLEWTDLVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSAL 636
            TGAN FR EW+ L+ ELV+  R+T A A +  ++ IVGLVGSIDNDFCGTDMTIG DSAL
Sbjct: 76   TGANIFRNEWSGLLAELVEKGRITDALAGQHQHLNIVGLVGSIDNDFCGTDMTIGADSAL 135

Query: 637  QRIISSIDAVVATAQS-------------HQRAFVIEVMGRHCGYLALVAALASEADFCF 777
             RI+  IDA++ TAQ              HQR FV+EVMGRHCGYLALV+ALAS AD+ F
Sbjct: 136  HRIMDIIDAIMTTAQRSEGRGQQPAQSVCHQRTFVLEVMGRHCGYLALVSALASGADWLF 195

Query: 778  IPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKY 957
            IPE P  E W D +C +L   R+ G RLNIII+AEGAID +GK I++  VK  V ++L Y
Sbjct: 196  IPEAPPKEGWEDHMCSRLEGSRTTGSRLNIIIIAEGAIDMNGKPISSTYVKDLVVKRLGY 255

Query: 958  DTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLL 1137
            DTR+T+LGHVQRGG PSAFDR+L  R+G EAV ALME + ++  CVI + GN  VR+PL+
Sbjct: 256  DTRLTVLGHVQRGGTPSAFDRILSSRLGIEAVIALMEASPDTPACVIGLSGNQAVRLPLM 315

Query: 1138 KCVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVAV 1317
            +CVE T++VQKAM ++ +  AV LRG SF+ N   YKLL   + V+ +      KF VA+
Sbjct: 316  ECVEMTKLVQKAMQERRFDEAVKLRGGSFENNWNIYKLLAYQKPVQTET-----KFTVAI 370

Query: 1318 INVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGS 1497
            +NVGAPAGGMNAAVRS  R+A+ H   VYG+ D F+GLA G   + +W +V  W   GGS
Sbjct: 371  LNVGAPAGGMNAAVRSAARLAIIHGHKVYGVHDGFQGLARGELFKMEWKNVAGWTGQGGS 430

Query: 1498 FLGTQKSLPTEKTMPQLAAQLKKHNIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCV 1677
             LGT+++LP E  M  +   ++K NI ALL++GGFE Y   + L E R  Y E CIPMCV
Sbjct: 431  LLGTKRTLPNEH-MESVVETIRKFNITALLVIGGFEGYEGVLQLFEARTHYEELCIPMCV 489

Query: 1678 IPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLS 1857
            IP TISNNVPGT  SLG+DTA+N +    DKIKQSA+GTKRRVF+VETMGGYCGYLAT +
Sbjct: 490  IPATISNNVPGTDFSLGADTAVNAVMDGCDKIKQSASGTKRRVFVVETMGGYCGYLATTA 549

Query: 1858 ALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLVV------------------ 1983
             +++GAD AYI+E+PF + DL+ +V+ +  KM+   +R LV+
Sbjct: 550  GIATGADAAYIYEDPFDIHDLTTNVEHLTEKMKKDVQRGLVLRCAATFSRLVSCVVLNFP 609

Query: 1984 --------RNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPFDRNMGTK 2139
                    RNE   +  TT+F+  L+ SEGK  F  RVNV GH+QQGG+P+PFDRN GTK
Sbjct: 610  IKGLLLHTRNEKCHEFYTTEFIHKLYSSEGKGIFDCRVNVFGHLQQGGAPSPFDRNYGTK 669

Query: 2140 LAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKKETDFEHRLP 2319
            +  RA+++L  ++ EN   D+ V A SA TA LLGL  + + F PV +LK  TDF+HR+P
Sbjct: 670  VGVRAIQWLTQKMTENFRQDH-VFANSADTACLLGLCRKVITFIPVTELKAATDFKHRMP 728

Query: 2320 SEQW 2331
            +EQW
Sbjct: 729  TEQW 732



 Score =  105 bits (262), Expect = 5e-21
 Identities = 107/408 (26%), Positives = 172/408 (41%), Gaps = 37/408 (9%)
 Frame = +1

Query: 139  TLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVSDI 318
            T+AI   G  + GMN+AVRS  R+AI  G KVY              F  E  W  V+
Sbjct: 367  TVAILNVGAPAGGMNAAVRSAARLAIIHGHKVYGVHDGFQGLARGELFKME--WKNVAGW 424

Query: 319  IQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLV 498
              QGG+++G+ R+      E  ++         I  L+ IGG     G      E
Sbjct: 425  TGQGGSLLGTKRTLPNEHMESVVETIRKF---NITALLVIGGFEGYEGVLQL-FEARTHY 480

Query: 499  QELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATA 678
            +EL                I +  +  +I N+  GTD ++G D+A+  ++   D +  +A
Sbjct: 481  EELC---------------IPMCVIPATISNNVPGTDFSLGADTAVNAVMDGCDKIKQSA 525

Query: 679  Q-SHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQ-MRSEG 852
              + +R FV+E MG +CGYLA  A +A+ AD  +I E P   +      + L++ M+ +
Sbjct: 526  SGTKRRVFVVETMGGYCGYLATTAGIATGADAAYIYEDPFDIHDLTTNVEHLTEKMKKDV 585

Query: 853  QR------------------LNIIIVAEGAIDRDGKA---ITAEDVKTAVKEKLK--YDT 963
            QR                  LN  I       R+ K     T E +      + K  +D
Sbjct: 586  QRGLVLRCAATFSRLVSCVVLNFPIKGLLLHTRNEKCHEFYTTEFIHKLYSSEGKGIFDC 645

Query: 964  RVTILGHVQRGGAPSAFDRLLGCRMGAEAV-FALMEMTEE-----------SEPCVISID 1107
            RV + GH+Q+GGAPS FDR  G ++G  A+ +   +MTE               C++ +
Sbjct: 646  RVNVFGHLQQGGAPSPFDRNYGTKVGVRAIQWLTQKMTENFRQDHVFANSADTACLLGLC 705

Query: 1108 GNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKL 1251
              V+  +P+ +    T    +   ++ W     L+ R   + L  Y++
Sbjct: 706  RKVITFIPVTELKAATDFKHRMPTEQWW-----LKFRPILKMLAKYQI 748


>gi|50732643|ref|XP_425972.1| PREDICTED: similar to MGC68847 protein
            [Gallus gallus]
          Length = 1667

 Score =  730 bits (1884), Expect = 0.0
 Identities = 392/781 (50%), Positives = 504/781 (64%), Gaps = 63/781 (8%)
 Frame = +1

Query: 178  MNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVSDIIQQGGTIIGSARS 357
            MN+AVR++ RM IY   KVY             D I E +W +VS I+Q GGT+IGSAR
Sbjct: 865  MNAAVRAVVRMGIYVKAKVYFVYEGYQGMVDGGDNIVEVSWESVSSILQVGGTVIGSARC 924

Query: 358  SEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQELVKNQRVTAAA 537
              FRTREGRL+AA NL+ RGI  L  IGGDGSLTGAN FR EW+ L++EL +  ++   A
Sbjct: 925  KSFRTREGRLQAAYNLVRRGITNLCVIGGDGSLTGANLFREEWSGLLEELAQKGKIDEEA 984

Query: 538  AKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQSHQRAFVIEVMG 717
             KK  Y+ IVG+VGSIDNDFCGTDMTIGTDSAL RII  +DA++ TAQ
Sbjct: 985  VKKYAYLNIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQR----------- 1033

Query: 718  RHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDR 897
                YLALV+ALA  AD+ FIPE+P  E W D +C KLS+ R+  +RLNIIIVAEGAID
Sbjct: 1034 ----YLALVSALACGADWVFIPEYPPEEGWEDSMCVKLSENRARKKRLNIIIVAEGAIDC 1089

Query: 898  DGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTE 1077
              K IT+E VK  V ++L +DTRVTILGHVQRGG PSAFDR+L  RMG EAV AL+E T
Sbjct: 1090 HNKPITSEKVKDLVVQRLGFDTRVTILGHVQRGGTPSAFDRILASRMGVEAVLALLEATP 1149

Query: 1078 ESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLLT 1257
            ++  CV+S+ GN  VR+PL++CV+ TQ VQKAM +  +  AV LRGRSF+ NL TYKLL+
Sbjct: 1150 DTPACVVSLSGNQAVRLPLMECVQMTQEVQKAMDEGRFVEAVRLRGRSFENNLNTYKLLS 1209

Query: 1258 KMRTVEKDNLSEGHKFNVAVINVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLAN 1437
            + +    D       FNVAV+NVGAPA GMNAAVR+ VR+ +     ++ + D FEG A
Sbjct: 1210 QKK---PDAELPKSNFNVAVLNVGAPAAGMNAAVRAAVRVGITEGHKMFAVIDGFEGFAR 1266

Query: 1438 GSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHNIQALLLVGGFEAYHS 1617
            G  K+  W DV  W   GGS LGT+++LP  K + ++A Q++ +NI AL+++GGFEAY
Sbjct: 1267 GKIKEISWGDVGGWTGQGGSILGTKRTLPA-KYLEKIADQMRTNNINALMVIGGFEAYLG 1325

Query: 1618 TIILAENREKYPEFCIPM------------------------------------------ 1671
             + L+  REKY EFC+PM
Sbjct: 1326 LLELSAAREKYDEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDAYESCLQLHDARS 1385

Query: 1672 ---------CVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKRRVFIVETM 1824
                     CV+P TISNNVPGT  S+G+DTA+N I +  D+IKQSA+GTKRRVFI+ETM
Sbjct: 1386 RFEEFCVPICVLPATISNNVPGTDFSIGADTALNAIVETCDRIKQSASGTKRRVFIIETM 1445

Query: 1825 GGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLVVRNEWADK 2004
            GGYCGYLA + AL++GAD AYIFEE F +++L  +V+ +  KM+   +R LV+RNE  ++
Sbjct: 1446 GGYCGYLANMGALAAGADAAYIFEEQFDIRELQANVEHLTEKMKTSIQRGLVLRNENCNE 1505

Query: 2005 NLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQ------------GGSPTPFDRNMGTKLAA 2148
            N TTDF+  L+  EGK  F  R NVLGH+QQ            GG+P+PFDRN GTK++A
Sbjct: 1506 NYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQVFHFCLKMGKKEGGAPSPFDRNFGTKISA 1565

Query: 2149 RALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQDLKKETDFEHRLPSEQ 2328
            +A++++  +LKE      KV A +  +  LLG++ R +VF PV +LK ETDF HR+P EQ
Sbjct: 1566 KAMQWISKKLKETY-RKGKVFANTDDSVCLLGMRRRNLVFQPVAELKNETDFVHRIPMEQ 1624

Query: 2329 W 2331
            W
Sbjct: 1625 W 1625



 Score =  102 bits (253), Expect = 5e-20
 Identities = 85/302 (28%), Positives = 151/302 (49%), Gaps = 25/302 (8%)
 Frame = +1

Query: 1339 GGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANG--SFKQFKWSDVTNWAMNGGSFLGTQ 1512
            G MNAAVR+ VRM +Y +  VY + + ++G+ +G  +  +  W  V++    GG+ +G+
Sbjct: 863  GCMNAAVRAVVRMGIYVKAKVYFVYEGYQGMVDGGDNIVEVSWESVSSILQVGGTVIGSA 922

Query: 1513 --KSLPTEKTMPQLAAQLKKHNIQALLLVGGFEAYHSTIILAE---------------NR 1641
              KS  T +   Q A  L +  I  L ++GG  +     +  E               +
Sbjct: 923  RCKSFRTREGRLQAAYNLVRRGITNLCVIGGDGSLTGANLFREEWSGLLEELAQKGKIDE 982

Query: 1642 EKYPEFC-IPMCVIPCTISNNVPGTMVSLGSDTAINEICQMIDKIKQSATGTKRRVFIVE 1818
            E   ++  + +  +  +I N+  GT +++G+D+A++ I +++D I  +A
Sbjct: 983  EAVKKYAYLNIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQ---------- 1032

Query: 1819 TMGGYCGYLATLSALSSGADNAYIFEEPFTVQDLSDDVDVILSKMEVGAKRY-LVVRNEW 1995
                   YLA +SAL+ GAD  +I E P   +   D + V LS+     KR  +++  E
Sbjct: 1033 ------RYLALVSALACGADWVFIPEYP-PEEGWEDSMCVKLSENRARKKRLNIIIVAEG 1085

Query: 1996 A----DKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALEF 2163
            A    +K +T++ V++L     +  F TRV +LGHVQ+GG+P+ FDR + +++   A+
Sbjct: 1086 AIDCHNKPITSEKVKDLVVQ--RLGFDTRVTILGHVQRGGTPSAFDRILASRMGVEAVLA 1143

Query: 2164 LL 2169
            LL
Sbjct: 1144 LL 1145



 Score =  100 bits (250), Expect = 1e-19
 Identities = 103/431 (23%), Positives = 173/431 (39%), Gaps = 62/431 (14%)
 Frame = +1

Query: 142  LAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVSDII 321
            +A+   G  + GMN+AVR+  R+ I  G K++               IKE +W  V
Sbjct: 1224 VAVLNVGAPAAGMNAAVRAAVRVGITEGHKMFAVIDGFEGFARGK--IKEISWGDVGGWT 1281

Query: 322  QQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTDLVQ 501
             QGG+I+G+ R+   +  E   K A  +    I  L+ IGG  +  G            +
Sbjct: 1282 GQGGSILGTKRTLPAKYLE---KIADQMRTNNINALMVIGGFEAYLGLLELSAAREKYDE 1338

Query: 502  ELVKNQRVTAAAAKKIP-----------------------------------YIQIVGLV 576
              V    V A  +  +P                                    + I  L
Sbjct: 1339 FCVPMVMVPATVSNNVPGSDFSIGADTALNTITDAYESCLQLHDARSRFEEFCVPICVLP 1398

Query: 577  GSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQ-SHQRAFVIEVMGRHCGYLALVAAL 753
             +I N+  GTD +IG D+AL  I+ + D +  +A  + +R F+IE MG +CGYLA + AL
Sbjct: 1399 ATISNNVPGTDFSIGADTALNAIVETCDRIKQSASGTKRRVFIIETMGGYCGYLANMGAL 1458

Query: 754  ASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRDGKAITAEDVKT 933
            A+ AD  +I E            + L++      +  +++  E       +  T + +
Sbjct: 1459 AAGADAAYIFEEQFDIRELQANVEHLTEKMKTSIQRGLVLRNENC----NENYTTDFIYQ 1514

Query: 934  AVKEKLK--YDTRVTILGHVQR------------GGAPSAFDRLLGCRMGAEAVFALMEM 1071
               E+ K  +D R  +LGH+Q+            GGAPS FDR  G ++ A+A+  + +
Sbjct: 1515 LYSEEGKGVFDCRKNVLGHMQQVFHFCLKMGKKEGGAPSPFDRNFGTKISAKAMQWISKK 1574

Query: 1072 TEES------------EPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRG 1215
             +E+              C++ +    +V  P+ +    T  V +   ++ W     L+
Sbjct: 1575 LKETYRKGKVFANTDDSVCLLGMRRRNLVFQPVAELKNETDFVHRIPMEQWW-----LKL 1629

Query: 1216 RSFQRNLETYK 1248
            R   + L  YK
Sbjct: 1630 RPLMKILAKYK 1640


>gi|1708594|sp|P52034|K6PF_DROME 6-phosphofructokinase
            (Phosphofructokinase) (Phosphohexokinase)
 gi|627155|pir||A55034 6-phosphofructokinase (EC 2.7.1.11) - fruit fly
            (Drosophila melanogaster)
 gi|514919|gb|AAA62385.1| phosphofructokinase
          Length = 787

 Score =  729 bits (1882), Expect = 0.0
 Identities = 393/742 (52%), Positives = 509/742 (67%), Gaps = 8/742 (1%)
 Frame = +1

Query: 130  KGRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTV 309
            K + LA++TSGGDSQGMN+AVR+  RMAIY GCKVY             D I+++ W +V
Sbjct: 16   KDKGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGDCIRKSNWASV 75

Query: 310  SDIIQQGGTIIGSARS-SEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEW 486
            S II   G      R   +FR R+GRLKAA NLI RGI  LV IGGDGSLTGAN    EW
Sbjct: 76   SSIIPFVGWHHPLLRPLPDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANLLPQEW 135

Query: 487  TDLVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAV 666
            + L+ ELVKN+ +T    +K   + ++GLVGSIDNDFCGTDMTIGTD+AL RII    A
Sbjct: 136  SSLLDELVKNKTITTEQQEKFNVLHMLGLVGSIDNDFCGTDMTIGTDTALHRIIEQSKAK 195

Query: 667  VATA---QSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLS- 834
            V +     SHQR F++E    HCGYLALV  LA EA    I   P            LS
Sbjct: 196  VQSPVQPNSHQRTFIMEGQVSHCGYLALVGGLACEA----IHIHPNAPGRLGQTGSALSW 251

Query: 835  QMRSEGQRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHVQRGGAPSAF 1014
              RS GQRLNI+IVAEGA+DR+G  ITAEDVK  + E+LK+D R+T+LGHVQRGG PSAF
Sbjct: 252  TQRSAGQRLNIVIVAEGAMDREGHPITAEDVKKVIDERLKHDARITVLGHVQRGGNPSAF 311

Query: 1015 DRLLGCRMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWT 1194
            DR L CRMGAE ++ LME T++S P VIS+DGN  VRVPL++CVERTQ   KAMA+K W
Sbjct: 312  DRFLACRMGAEPLWPLMEATKDSVPVVISLDGNQAVRVPLMECVERTQ-AGKAMAEKRWA 370

Query: 1195 TAVMLRGRSFQRNLETYKLLTKMRTVEKDNLSEG---HKFNVAVINVGAPAGGMNAAVRS 1365
             AV +RGRSF+RNLETYK+LT+++  +++  ++G     + +AV+++GAPA GMNAAVRS
Sbjct: 371  DAVNVRGRSFERNLETYKMLTRLKPPKENFDADGKGIEGYRLAVMHIGAPACGMNAAVRS 430

Query: 1366 YVRMALYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKSLPTEKTMPQ 1545
            +VR A+Y    VYGI D  EGL   + ++  WSDV+ W   GG++LG++++LP  K   +
Sbjct: 431  FVRNAIYRGDVVYGINDGVEGLIARNVRELGWSDVSGWVGQGGAYLGSKRTLPEGK-FKE 489

Query: 1546 LAAQLKKHNIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSL 1725
            +AA+LK+  IQ LL++GGFE+YH+   +A+ R     FCIP+ VIP TISNNVPGT  SL
Sbjct: 490  IAARLKEFKIQGLLIIGGFESYHAAGQIADQRTTTHSFCIPIVVIPSTISNNVPGTEFSL 549

Query: 1726 GSDTAINEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPF 1905
            G DT +NEI ++ D+I+QSA GTKRRVF++ETMGGYCGYL  L+ L+ GAD AYI+EE F
Sbjct: 550  GCDTGLNEITEICDRIRQSAQGTKRRVFVIETMGGYCGYLPPLAGLAGGADAAYIYEEKF 609

Query: 1906 TVQDLSDDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLG 2085
            ++++L  DV  +  +      R     NE A +N +TDF+  L+  EGK  FT R+N+LG
Sbjct: 610  SIKELQQDVYHMPPRWPRRLPRSNPA-NEKASENYSTDFIYRLYSEEGKGLFTCRMNILG 668

Query: 2086 HVQQGGSPTPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVV 2265
            H+QQGGSPTPFDRNMGTK+AA+ ++    + +   TA+  V  KS  TATLLG+  R+
Sbjct: 669  HMQQGGSPTPFDRNMGTKMAAKCVDCWPPRSRRTSTANGVVNCKSPDTATLLGIVSRQYR 728

Query: 2266 FTPVQDLKKETDFEHRLPSEQW 2331
            F+P+ DL  ET+F+ R+P +QW
Sbjct: 729  FSPLVDLIAETNFDQRIPKKQW 750


>gi|47225149|emb|CAF98776.1| unnamed protein product [Tetraodon
            nigroviridis]
          Length = 839

 Score =  722 bits (1863), Expect = 0.0
 Identities = 395/810 (48%), Positives = 502/810 (61%), Gaps = 125/810 (15%)
 Frame = +1

Query: 277  DFIKEATWNTVSDIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSL 456
            D I+EATW +VS ++Q GGT+IGSAR  EFRT EGRLKAA NL+ RGI  L  IGGDGSL
Sbjct: 6    DNIREATWESVSSMLQVGGTVIGSARCKEFRTHEGRLKAAHNLVQRGITNLCVIGGDGSL 65

Query: 457  TGANTFRLEWTDLVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSAL 636
            TGAN FR EW+ L+ ELV+   +   + +K   + IVG+VGSIDNDFCGTDMTIGTDSAL
Sbjct: 66   TGANLFREEWSGLLTELVEQGLIEQDSIQKYSALHIVGMVGSIDNDFCGTDMTIGTDSAL 125

Query: 637  QRIISSIDAVVATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDV 816
             RII  +DA++ TAQSHQR FV+EVMGRHCGYLALV+ALA  AD+  IPE P  + W D
Sbjct: 126  HRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVLIPEMPPEDGWEDK 185

Query: 817  LCDKLSQMRSEG---------------------------------------------QRL 861
            +C KLS  RS G                                             +RL
Sbjct: 186  MCQKLSATRSRGTRLNIIIVAEGAIDRHGKPITSSFVKDFRSCLATMLLKAQNRAGKKRL 245

Query: 862  NIIIVAEGAIDRDGKAITAEDVKTA-----------------------------VKEKLK 954
            N+IIVAEGAIDR    IT + +K                               V + L
Sbjct: 246  NVIIVAEGAIDRSNTPITTDYIKDVSTELCVRVWRFPHLGCLLCDLYHCTAALLVVKNLG 305

Query: 955  YDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEESEPCVISIDGNVMVRVPL 1134
            +DTRVTILGHVQRGG PSAFDR+L  RMG EAV AL+E T  +  CV+S+ GN  VR+PL
Sbjct: 306  FDTRVTILGHVQRGGTPSAFDRILASRMGVEAVLALLETTANTPACVVSLCGNQSVRLPL 365

Query: 1135 LKCVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLLTKMRTVEKDNLSEGHKFNVA 1314
            ++CVE TQ VQKAM +K +  AV LRGRSF+ NL+TYKLL   R  E D       FNVA
Sbjct: 366  MECVEMTQEVQKAMDEKRFEEAVKLRGRSFENNLKTYKLLAH-RKPESD--LPHSNFNVA 422

Query: 1315 VINVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGG 1494
            V+NVGAPA GMNAAVRS VR+ +     ++ + D FEG   G  K+ KW+DV  W   GG
Sbjct: 423  VLNVGAPAAGMNAAVRSAVRVGISEGHKMFAVSDGFEGFYKGQIKEIKWADVGGWTGQGG 482

Query: 1495 SFLGTQKSLPTEKTMPQLAAQLKKHNIQALLLVGGFE----------------------- 1605
            S LGT+++LP  K + ++AAQ+++HNI ALL++GGFE
Sbjct: 483  SLLGTKRTLPA-KHVDKIAAQMRQHNINALLIIGGFEGFLSLLELLTARGKYEELCVPMV 541

Query: 1606 ----------------------------AYHSTIILAENREKYPEFCIPMCVIPCTISNN 1701
                                        A+ S + L E R  Y EFCIPMC++P TISNN
Sbjct: 542  MVPATVSNNVPGSDLSIGADTALNAITSAFESLLQLFEARATYEEFCIPMCMVPATISNN 601

Query: 1702 VPGTMVSLGSDTAINEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADN 1881
            VPGT +S+G+DTA+N I +  D+IKQSA+GTKRRVFI+ETMGGYCGYLA++  L++GAD
Sbjct: 602  VPGTNLSIGADTALNAIVETCDRIKQSASGTKRRVFIIETMGGYCGYLASVGGLAAGADA 661

Query: 1882 AYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNF 2061
            AYI+EE F ++DL  +V+ +  KM+   +R LV+RNE +++N TTDF+  L+  EG+  F
Sbjct: 662  AYIYEESFDIRDLQANVEHLTEKMKTSIQRGLVLRNENSNENYTTDFIYQLYSEEGRGVF 721

Query: 2062 TTRVNVLGHVQQGGSPTPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLL 2241
              R NVLGH+QQGG+P+PFDRN GTK++A+A++++  +L E      +V A S  +  LL
Sbjct: 722  DCRKNVLGHMQQGGAPSPFDRNFGTKISAKAMQWVTRKLGETF-RQGRVFANSEDSCCLL 780

Query: 2242 GLKGRKVVFTPVQDLKKETDFEHRLPSEQW 2331
            G++ R +VF PV  LK ETDF HR+P EQW
Sbjct: 781  GMRRRALVFQPVVQLKDETDFVHRIPKEQW 810



 Score =  106 bits (265), Expect = 2e-21
 Identities = 107/426 (25%), Positives = 181/426 (42%), Gaps = 57/426 (13%)
 Frame = +1

Query: 142  LAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVSDII 321
            +A+   G  + GMN+AVRS  R+ I  G K++               IKE  W  V
Sbjct: 421  VAVLNVGAPAAGMNAAVRSAVRVGISEGHKMFAVSDGFEGFYKGQ--IKEIKWADVGGWT 478

Query: 322  QQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGG-DG--SLTGANTFRLEWTD 492
             QGG+++G+ R+   +  +   K A  +    I  L+ IGG +G  SL    T R ++ +
Sbjct: 479  GQGGSLLGTKRTLPAKHVD---KIAAQMRQHNINALLIIGGFEGFLSLLELLTARGKYEE 535

Query: 493  LVQELVKNQRVTAAAAKKIP-----------------------------------YIQIV 567
            L   +V    V A  +  +P                                    I +
Sbjct: 536  LCVPMVM---VPATVSNNVPGSDLSIGADTALNAITSAFESLLQLFEARATYEEFCIPMC 592

Query: 568  GLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVATAQ-SHQRAFVIEVMGRHCGYLALV 744
             +  +I N+  GT+++IG D+AL  I+ + D +  +A  + +R F+IE MG +CGYLA V
Sbjct: 593  MVPATISNNVPGTNLSIGADTALNAIVETCDRIKQSASGTKRRVFIIETMGGYCGYLASV 652

Query: 745  AALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRDGKAITAED 924
              LA+ AD  +I E            + L++      +  +++  E + +      T +
Sbjct: 653  GGLAAGADAAYIYEESFDIRDLQANVEHLTEKMKTSIQRGLVLRNENSNEN----YTTDF 708

Query: 925  VKTAVKEKLK--YDTRVTILGHVQRGGAPSAFDRLLGCRMGAEA---------------- 1050
            +     E+ +  +D R  +LGH+Q+GGAPS FDR  G ++ A+A
Sbjct: 709  IYQLYSEEGRGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISAKAMQWVTRKLGETFRQGR 768

Query: 1051 VFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQKAMADKDWTTAVMLRGRSFQR 1230
            VFA      E   C++ +    +V  P+++  + T  V +   ++ W     L+ R   +
Sbjct: 769  VFA----NSEDSCCLLGMRRRALVFQPVVQLKDETDFVHRIPKEQWW-----LKLRPLMK 819

Query: 1231 NLETYK 1248
             L  YK
Sbjct: 820  ILAKYK 825


>gi|47228737|emb|CAG07469.1| unnamed protein product [Tetraodon
            nigroviridis]
          Length = 836

 Score =  665 bits (1715), Expect = 0.0
 Identities = 369/797 (46%), Positives = 500/797 (62%), Gaps = 64/797 (8%)
 Frame = +1

Query: 133  GRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTVS 312
            GR++A+ TSGGD+QGMN+AVR+  R+ +Y G KVY             + I+ ATW +VS
Sbjct: 17   GRSIAVLTSGGDAQGMNAAVRATVRVGLYTGAKVYFVHEGYQGLVDGGERIRLATWESVS 76

Query: 313  DIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGGDGSLTGANTFRLEWTD 492
             ++Q GGT+IGSAR  +FR+REGR+KAA NL+  GI  L  IGGDGSLTGAN FR EW+
Sbjct: 77   MMLQLGGTVIGSARCKDFRSREGRMKAAANLVKLGITNLCVIGGDGSLTGANEFRTEWSG 136

Query: 493  LVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAVVA 672
            L+ +LV+  R+T   AKK  ++ IVG+VGSIDNDFCGTDMTIGTDSAL RII  +DA+
Sbjct: 137  LLADLVQAGRITEQEAKKSSHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAITT 196

Query: 673  TAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENWRDVLCDKLSQMRSEG 852
            TAQSHQR F++EVMGRHCGYLALV A A  AD+ FIPE P    W D LC +L+
Sbjct: 197  TAQSHQRTFILEVMGRHCGYLALVTAQACGADWVFIPEMPPEHGWEDHLCRRLADPGLSS 256

Query: 853  QR-------------LNIIIVAEGAIDRDG-------KAITAEDVKTAVKEKLKYDTRVT 972
            QR              N +   + A DR         +  T  + + AV   ++ +   +
Sbjct: 257  QRDHRGRGRHVQRRQTNHVRPDQEAGDRQAGLRHPHHRFGTRAEGRDAVG--VRQNPGES 314

Query: 973  ILGHVQR-GGAPSAFDRLL---GCRMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLK 1140
            + G   R  GA    +  +   G RMG EAV AL+E T ++  CV+S+ GN  VR+PL++
Sbjct: 315  LGGATNREAGAEQTQEPPVSPQGSRMGVEAVMALLEATPDTPACVVSLSGNQAVRLPLME 374

Query: 1141 CVERTQMVQKAMADKDWTTAVMLRGRSFQRNLETYKLLTKMRTVE-KDNLSEGHKFNVAV 1317
            CV+ T+ V  AMA+  +  AV LRG+SF+ N  TYKLL  +   + K N+      N+A+
Sbjct: 375  CVQVTKDVTAAMAEGRFEDAVKLRGKSFENNWNTYKLLAHINPPDVKSNI------NMAI 428

Query: 1318 INVGAPAGGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANGS-----------FKQFK-- 1458
            +N+GAP  GMNAAVR+ VRM +     +  + D F+GLA G            F Q +
Sbjct: 429  MNIGAPCAGMNAAVRAAVRMGIIQGHNMLAVHDGFDGLAQGQVPLLWSPVMLMFPQIEPI 488

Query: 1459 -WSDVTNWAMNGGSFLGTQKSLPTEKTMPQLAAQLKKHNIQALLLVGGFE---------- 1605
             W+ V+ W   GGS LGT++SLP  K + +++  + + NI AL++VGGFE
Sbjct: 489  GWTSVSGWTGKGGSMLGTKRSLPG-KMLEEISQNISRFNIHALVIVGGFEVSCGGGSKLP 547

Query: 1606 ---------------AYHSTIILAENREKYPEFCIPMCVIPCTISNNVPGTMVSLGSDTA 1740
                           AY   + L + REKY E CIPM VIP T+SNNVPG+  S+G+DTA
Sbjct: 548  APAELLYIVPPTCPQAYVGGLELVQAREKYEEMCIPMVVIPATVSNNVPGSDFSIGADTA 607

Query: 1741 INEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGADNAYIFEEPFTVQDL 1920
            +N I    D+IKQSA GTKRRVFIVETMGGYCGYLAT++ L++GAD AYIFEE F+++DL
Sbjct: 608  LNTITSTCDRIKQSAAGTKRRVFIVETMGGYCGYLATMAGLAAGADAAYIFEEKFSIKDL 667

Query: 1921 SDDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKNFTTRVNVLGHVQQG 2100
              +V  ++ KM+   KR L++RNE ++ N TTDF+ NL+  EGK  F  R NVLGH+QQG
Sbjct: 668  ETNVKHLVKKMKTTVKRGLILRNENSNANYTTDFIFNLYSEEGKGVFDCRKNVLGHMQQG 727

Query: 2101 GSPTPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATLLGLKGRKVVFTPVQ 2280
            G+PTPFDRN GTK+ A+++ +L  +LKE      ++ A +  +A +LG++ R ++F P+
Sbjct: 728  GTPTPFDRNFGTKMGAKSVLWLTDKLKE-CYRHGRIFANTPESACVLGMRKRALMFQPLA 786

Query: 2281 DLKKETDFEHRLPSEQW 2331
            +LK++TD EHR+P  QW
Sbjct: 787  ELKEDTDLEHRIPRTQW 803



 Score =  103 bits (258), Expect = 1e-20
 Identities = 99/393 (25%), Positives = 167/393 (42%), Gaps = 36/393 (9%)
 Frame = +1

Query: 121  DIFKGRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXX-------- 276
            D+     +AI   G    GMN+AVR+  RM I  G  +
Sbjct: 419  DVKSNINMAIMNIGAPCAGMNAAVRAAVRMGIIQGHNMLAVHDGFDGLAQGQVPLLWSPV 478

Query: 277  ----DFIKEATWNTVSDIIQQGGTIIGSARSSEFRTREGRLKAATNLINRGIGRLVCIGG 444
                  I+   W +VS    +GG+++G+ RS   +  E   + + N+    I  LV +GG
Sbjct: 479  MLMFPQIEPIGWTSVSGWTGKGGSMLGTKRSLPGKMLE---EISQNISRFNIHALVIVGG 535

Query: 445  DGSLTGANTFRLEWTDLV--------QELVKNQRVTAAAAK-KIPYIQIVGLVGSIDNDF 597
                 G  +      +L+        Q  V    +  A  K +   I +V +  ++ N+
Sbjct: 536  FEVSCGGGSKLPAPAELLYIVPPTCPQAYVGGLELVQAREKYEEMCIPMVVIPATVSNNV 595

Query: 598  CGTDMTIGTDSALQRIISSIDAVVATAQ-SHQRAFVIEVMGRHCGYLALVAALASEADFC 774
             G+D +IG D+AL  I S+ D +  +A  + +R F++E MG +CGYLA +A LA+ AD
Sbjct: 596  PGSDFSIGADTALNTITSTCDRIKQSAAGTKRRVFIVETMGGYCGYLATMAGLAAGADAA 655

Query: 775  FIPEWPAPENWRDVLCDKLSQMRSEGQRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLK 954
            +I E        +     L +      +  +I+  E +        T + +     E+ K
Sbjct: 656  YIFEEKFSIKDLETNVKHLVKKMKTTVKRGLILRNENS----NANYTTDFIFNLYSEEGK 711

Query: 955  --YDTRVTILGHVQRGGAPSAFDRLLGCRMGAEAVFALMEMTEE------------SEPC 1092
              +D R  +LGH+Q+GG P+ FDR  G +MGA++V  L +  +E               C
Sbjct: 712  GVFDCRKNVLGHMQQGGTPTPFDRNFGTKMGAKSVLWLTDKLKECYRHGRIFANTPESAC 771

Query: 1093 VISIDGNVMVRVPLLKCVERTQMVQKAMADKDW 1191
            V+ +    ++  PL +  E T +  +    + W
Sbjct: 772  VLGMRKRALMFQPLAELKEDTDLEHRIPRTQWW 804


>gi|25009881|gb|AAN71109.1| AT27295p [Drosophila melanogaster]
          Length = 606

 Score =  637 bits (1643), Expect = 0.0
 Identities = 318/571 (55%), Positives = 423/571 (73%), Gaps = 3/571 (0%)
 Frame = +1

Query: 628  SALQRIISSIDAVVATAQSHQRAFVIEVMGRHCGYLALVAALASEADFCFIPEWPAPENW 807
            S+ Q + S +     +A S  R++V+          A+ AA+A+EADF FIPE P   NW
Sbjct: 8    SSRQSMPSPVQPTPISAPSSWRSWVV--------IAAISAAIATEADFMFIPEEPVSVNW 59

Query: 808  RDVLCDKLSQMRSEGQRLNIIIVAEGAIDRDGKAITAEDVKTAVKEKLKYDTRVTILGHV 987
            +D +C KL Q RS GQRLNI+IVAEGA+DR+G  ITAEDVK  + E+LK+D R+T+LGHV
Sbjct: 60   KDEICVKLHQERSAGQRLNIVIVAEGAMDREGHPITAEDVKKVIDERLKHDARITVLGHV 119

Query: 988  QRGGAPSAFDRLLGCRMGAEAVFALMEMTEESEPCVISIDGNVMVRVPLLKCVERTQMVQ 1167
            QRGG PSAFDR+L CRMGAEA  ALME T++S P VIS+DGN  VRVPL++CVERTQ V
Sbjct: 120  QRGGNPSAFDRILACRMGAEATLALMEATKDSVPVVISLDGNQAVRVPLMECVERTQAVA 179

Query: 1168 KAMADKDWTTAVMLRGRSFQRNLETYKLLTKMRTVEKDNLSEG---HKFNVAVINVGAPA 1338
            KAMA+K W  AV LRGRSF+RNLETYK+LT+++  +++  ++G     + +AV+++GAPA
Sbjct: 180  KAMAEKRWADAVKLRGRSFERNLETYKMLTRLKPPKENFDADGKGIEGYRLAVMHIGAPA 239

Query: 1339 GGMNAAVRSYVRMALYHQCTVYGIEDSFEGLANGSFKQFKWSDVTNWAMNGGSFLGTQKS 1518
             GMNAAVRS+VR A+Y    VYGI D  EGL  G+ ++  WSDV+ W   GG++LGT+++
Sbjct: 240  CGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRT 299

Query: 1519 LPTEKTMPQLAAQLKKHNIQALLLVGGFEAYHSTIILAENREKYPEFCIPMCVIPCTISN 1698
            LP  K   ++AA+LK+  IQ LL++GGFE+YH+   +A+ R+ YP+FCIP+ VIP TISN
Sbjct: 300  LPEGK-FKEIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDNYPQFCIPIVVIPSTISN 358

Query: 1699 NVPGTMVSLGSDTAINEICQMIDKIKQSATGTKRRVFIVETMGGYCGYLATLSALSSGAD 1878
            NVPGT  SLG DT +NEI ++ D+I+QSA GTKRRVF++ETMGGYCGYLATL+ L+ GAD
Sbjct: 359  NVPGTEFSLGCDTGLNEITEICDRIRQSAQGTKRRVFVIETMGGYCGYLATLAGLAGGAD 418

Query: 1879 NAYIFEEPFTVQDLSDDVDVILSKMEVGAKRYLVVRNEWADKNLTTDFVQNLFDSEGKKN 2058
             AYI+EE F+++DL  DV  + SKM  G  R L++RNE A +N +TDF+  L+  EGK
Sbjct: 419  AAYIYEEKFSIKDLQQDVYHMASKMAEGVSRGLILRNEKASENYSTDFIYRLYSEEGKGL 478

Query: 2059 FTTRVNVLGHVQQGGSPTPFDRNMGTKLAARALEFLLIQLKENLTADNKVIAKSAHTATL 2238
            FT R+N+LGH+QQGGSPTPFDRNMGTK+AA+ +++L  Q+K N+ A+  V  KS  TATL
Sbjct: 479  FTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLAAQIKANIDANGVVNCKSPDTATL 538

Query: 2239 LGLKGRKVVFTPVQDLKKETDFEHRLPSEQW 2331
            LG+  R+  F+P+ DL  ET+F+ R+P +QW
Sbjct: 539  LGIVSRQYRFSPLVDLIAETNFDQRIPKKQW 569



 Score =  112 bits (281), Expect = 3e-23
 Identities = 102/319 (31%), Positives = 152/319 (46%), Gaps = 11/319 (3%)
 Frame = +1

Query: 130  KGRTLAIYTSGGDSQGMNSAVRSITRMAIYCGCKVYLXXXXXXXXXXXXDFIKEATWNTV 309
            +G  LA+   G  + GMN+AVRS  R AIY G  VY               ++E  W+ V
Sbjct: 226  EGYRLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVY--GINDGVEGLIAGNVRELGWSDV 283

Query: 310  SDIIQQGGTIIGSARSSEFRTREGRLK-AATNLINRGIGRLVCIGGDGSLTGANTFRLEW 486
            S  + QGG  +G+ R+      EG+ K  A  L    I  L+ IGG  S   A     +
Sbjct: 284  SGWVGQGGAYLGTKRT----LPEGKFKEIAARLKEFKIQGLLIIGGFESYHAAGQIADQR 339

Query: 487  TDLVQELVKNQRVTAAAAKKIPYIQIVGLVGSIDNDFCGTDMTIGTDSALQRIISSIDAV 666
             +  Q                  I IV +  +I N+  GT+ ++G D+ L  I    D +
Sbjct: 340  DNYPQFC----------------IPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRI 383

Query: 667  VATAQ-SHQRAFVIEVMGRHCGYLALVAALASEADFCFIPE--WPAPENWRDVLCDKLSQ 837
              +AQ + +R FVIE MG +CGYLA +A LA  AD  +I E  +   +  +DV    ++
Sbjct: 384  RQSAQGTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLQQDVY--HMAS 441

Query: 838  MRSEGQRLNIIIVAEGAIDRDGKAITAEDVKT-------AVKEKLKYDTRVTILGHVQRG 996
              +EG       V+ G I R+ KA  +E+  T       + + K  +  R+ ILGH+Q+G
Sbjct: 442  KMAEG-------VSRGLILRNEKA--SENYSTDFIYRLYSEEGKGLFTCRMNILGHMQQG 492

Query: 997  GAPSAFDRLLGCRMGAEAV 1053
            G+P+ FDR +G +M A+ V
Sbjct: 493  GSPTPFDRNMGTKMAAKCV 511




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