Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= Y76B12C_7
(4365 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|25148482|ref|NP_500157.2| cleavage polyadenylation specific f... 2777 0.0
gi|39594178|emb|CAE70288.1| Hypothetical protein CBG16808 [Caeno... 2364 0.0
gi|23503048|sp|Q10570|CPSA_HUMAN Cleavage and polyadenylation sp... 767 0.0
gi|16751835|ref|NP_444423.1| cleavage and polyadenylation specif... 766 0.0
gi|27807297|ref|NP_777145.1| cleavage and polyadenylation specif... 763 0.0
gi|9558725|ref|NP_037423.1| cleavage and polyadenylation specifi... 763 0.0
gi|34867012|ref|XP_345850.1| similar to cleavage and polyadenyla... 762 0.0
gi|47217773|emb|CAG05995.1| unnamed protein product [Tetraodon n... 719 0.0
gi|45552619|ref|NP_995833.1| CG10110-PA [Drosophila melanogaster... 696 0.0
gi|31200727|ref|XP_309311.1| ENSANGP00000018461 [Anopheles gambi... 678 0.0
gi|24653655|ref|NP_725397.1| CG10110-PB [Drosophila melanogaster... 649 0.0
gi|49619065|gb|AAT68117.1| cleavage and polyadenylation specific... 542 e-152
gi|33411762|emb|CAD58786.1| cleavage and polyadenylation specifi... 401 e-110
gi|9794908|gb|AAF98388.1| cleavage and polyadenylation specifici... 384 e-105
gi|19112233|ref|NP_595441.1| putative cleavage and polyadenylati... 362 6e-98
gi|9794904|gb|AAF98386.1| cleavage and polyadenylation specifici... 268 9e-70
gi|38014465|gb|AAH60475.1| LOC398931 protein [Xenopus laevis] 252 5e-65
gi|49619061|gb|AAT68115.1| cleavage and polyadenylation specific... 229 3e-58
gi|18202900|sp|Q9FGR0|CPSA_ARATH Probable cleavage and polyadeny... 216 4e-54
gi|24415580|gb|AAN41460.1| putative cleavage and polyadenylation... 215 9e-54
gi|30696088|ref|NP_199979.2| cleavage and polyadenylation specif... 215 9e-54
gi|50257351|gb|EAL20060.1| hypothetical protein CNBF3860 [Crypto... 203 3e-50
gi|38345987|emb|CAD39979.2| OSJNBa0032B23.5 [Oryza sativa (japon... 201 2e-49
gi|50427411|ref|XP_462318.1| unnamed protein product [Debaryomyc... 167 2e-39
gi|50552095|ref|XP_503522.1| hypothetical protein [Yarrowia lipo... 166 6e-39
gi|32417588|ref|XP_329272.1| hypothetical protein [Neurospora cr... 164 1e-38
gi|49087160|ref|XP_405550.1| hypothetical protein AN1413.2 [Aspe... 146 5e-33
gi|46120520|ref|XP_385083.1| hypothetical protein FG04907.1 [Gib... 140 4e-31
gi|46442380|gb|EAL01670.1| hypothetical protein CaO19.2760 [Cand... 139 6e-31
gi|46442138|gb|EAL01430.1| hypothetical protein CaO19.10274 [Can... 139 8e-31
gi|49077388|ref|XP_402559.1| hypothetical protein UM04944.1 [Ust... 135 1e-29
gi|12697776|dbj|BAB21613.1| polyadenylation specificity factor [... 134 3e-29
gi|50288865|ref|XP_446862.1| unnamed protein product [Candida gl... 127 3e-27
gi|38102215|gb|EAA49081.1| hypothetical protein MG00739.4 [Magna... 124 2e-26
gi|6320507|ref|NP_010587.1| Functions in cleavage of 3'-ends of ... 121 2e-25
gi|50305395|ref|XP_452657.1| unnamed protein product [Kluyveromy... 118 1e-24
gi|45184764|ref|NP_982482.1| AAL060Wp [Eremothecium gossypii] >g... 111 2e-22
gi|9794906|gb|AAF98387.1| cleavage and polyadenylation specifici... 110 2e-22
gi|33411764|emb|CAD58787.1| cleavage and polyadenylation specifi... 106 6e-21
gi|41055225|ref|NP_956920.1| hypothetical protein MGC63840 [Dani... 102 6e-20
gi|13435359|ref|NP_001914.2| damage-specific DNA binding protein... 100 3e-19
gi|16197726|emb|CAC94909.1| damaged-DNA recognition protein 1 [M... 99 7e-19
gi|12643730|sp|Q16531|DDB1_HUMAN DNA damage binding protein 1 (D... 99 7e-19
gi|418316|sp|P33194|DDB1_CERAE DNA damage binding protein 1 (Dam... 99 7e-19
gi|2632123|emb|CAA05770.1| Xeroderma Pigmentosum Group E Complem... 99 7e-19
gi|47230701|emb|CAF99894.1| unnamed protein product [Tetraodon n... 98 2e-18
gi|34861615|ref|XP_342025.1| similar to DNA damage binding prote... 98 2e-18
gi|45383688|ref|NP_989547.1| damage-specific DNA binding protein... 98 2e-18
gi|7657011|ref|NP_056550.1| damage specific DNA binding protein ... 97 3e-18
gi|11275251|pir||JC7152 UV-damaged DNA-binding 127K protein - mouse 97 3e-18
gi|38303806|gb|AAH61946.1| MGC68476 protein [Xenopus laevis] 97 3e-18
gi|12082087|dbj|BAB20761.1| UV-damaged DNA binding protein [Oryz... 97 4e-18
gi|48475231|gb|AAT44300.1| putative DNA damage binding protein 1... 97 4e-18
gi|25282451|ref|NP_741992.1| damage-specific DNA binding protein... 97 4e-18
gi|5353754|gb|AAD42230.1| damage-specific DNA binding protein 1 ... 96 6e-18
gi|21357503|ref|NP_650257.1| CG7769-PA [Drosophila melanogaster]... 94 3e-17
gi|50363265|gb|AAT75335.1| cleavage polyadenylation specificity ... 93 6e-17
gi|15235577|ref|NP_192451.1| UV-damaged DNA-binding protein, put... 83 7e-14
gi|31206999|ref|XP_312466.1| ENSANGP00000003051 [Anopheles gambi... 83 7e-14
gi|38455768|gb|AAR20885.1| UV damaged DNA binding protein 1 [Lyc... 82 9e-14
gi|49484911|gb|AAT66742.1| UV-damaged DNA binding protein 1 [Lyc... 82 9e-14
gi|7440006|pir||T04941 UV-damaged DNA-binding protein homolog F7... 78 2e-12
gi|15233515|ref|NP_193842.1| UV-damaged DNA-binding protein, put... 78 2e-12
gi|17541566|ref|NP_502299.1| CPSF A subunit C-terminal (125.7 kD... 78 2e-12
gi|48106082|ref|XP_396048.1| similar to ENSANGP00000003051 [Apis... 77 5e-12
gi|18377609|gb|AAL66955.1| putative UV-damaged DNA binding facto... 74 4e-11
gi|39593892|emb|CAE62185.1| Hypothetical protein CBG06232 [Caeno... 73 7e-11
gi|46442139|gb|EAL01431.1| hypothetical protein CaO19.10275 [Can... 72 9e-11
gi|19074861|ref|NP_586367.1| CLEAVAGE AND POLYADENYLATION SPECIF... 72 1e-10
gi|25294327|pir||A88855 protein M18.5 [imported] - Caenorhabditi... 62 1e-07
gi|2130171|pir||S71092 UV-damaged DNA binding protein repE - sli... 62 2e-07
gi|50801619|ref|XP_428554.1| PREDICTED: hypothetical protein XP_... 60 6e-07
gi|19115326|ref|NP_594414.1| prp12p/sap130. [Schizosaccharomyces... 58 2e-06
gi|50257071|gb|EAL19786.1| hypothetical protein CNBG0790 [Crypto... 53 7e-05
gi|46439394|gb|EAK98712.1| hypothetical protein CaO19.12846 [Can... 52 2e-04
gi|49096258|ref|XP_409589.1| hypothetical protein AN5452.2 [Aspe... 51 2e-04
gi|19114492|ref|NP_593580.1| putative (Xeroderma pigmentosum-gro... 51 3e-04
gi|47087273|ref|NP_998668.1| zgc:55440 [Danio rerio] >gnl|BL_ORD... 48 0.002
gi|32403738|ref|XP_322482.1| hypothetical protein [Neurospora cr... 48 0.002
gi|47212603|emb|CAF93045.1| unnamed protein product [Tetraodon n... 47 0.004
gi|39595801|emb|CAE67304.1| Hypothetical protein CBG12757 [Caeno... 47 0.004
gi|50753573|ref|XP_414047.1| PREDICTED: similar to KIAA0017 prot... 46 0.007
gi|40788938|dbj|BAA32662.2| KIAA0017 protein [Homo sapiens] 46 0.009
gi|40254849|ref|NP_036558.2| splicing factor 3b, subunit 3, 130k... 46 0.009
gi|46362557|gb|AAH68974.1| Splicing factor 3b, subunit 3, 130kDa... 46 0.009
gi|19527174|ref|NP_598714.1| splicing factor 3b, subunit 3, 130k... 46 0.009
gi|37359734|dbj|BAC97845.1| mKIAA0017 protein [Mus musculus] 46 0.009
gi|34851925|ref|XP_214697.2| similar to RIKEN cDNA 1810061H24 [R... 46 0.009
gi|17508021|ref|NP_491953.1| splicing factor (1H409) [Caenorhabd... 45 0.020
gi|26338446|dbj|BAC32894.1| unnamed protein product [Mus musculus] 43 0.077
gi|24639885|ref|NP_572231.1| CG15781-PA [Drosophila melanogaster... 42 0.17
gi|31213215|ref|XP_315551.1| ENSANGP00000017759 [Anopheles gambi... 40 0.38
gi|38110822|gb|EAA56486.1| hypothetical protein MG06457.4 [Magna... 40 0.65
gi|31201487|ref|XP_309691.1| ENSANGP00000012571 [Anopheles gambi... 39 0.85
gi|32411959|ref|XP_326460.1| hypothetical protein [Neurospora cr... 39 1.1
gi|50427669|ref|XP_462447.1| unnamed protein product [Debaryomyc... 39 1.5
gi|19114436|ref|NP_593524.1| ras-related protein rab-7 [Schizosa... 39 1.5
gi|24654874|ref|NP_728546.1| CG13900-PA [Drosophila melanogaster... 38 2.5
gi|48847144|ref|ZP_00301401.1| COG1157: Flagellar biosynthesis/t... 37 3.2
gi|16077984|ref|NP_388800.1| yhcR [Bacillus subtilis subsp. subt... 37 3.2
gi|49899749|gb|AAH76786.1| Unknown (protein for MGC:83700) [Xeno... 37 5.5
gi|23613154|ref|NP_703476.1| hypothetical protein [Plasmodium fa... 37 5.5
gi|46121747|ref|XP_385428.1| hypothetical protein FG05252.1 [Gib... 37 5.5
gi|2127423|pir||B40626 probable 2,3-dihydrodipicolinate N-C6-lya... 36 7.2
gi|46107840|ref|XP_380979.1| hypothetical protein FG00803.1 [Gib... 36 7.2
gi|45200913|ref|NP_986483.1| AGL184Wp [Eremothecium gossypii] >g... 36 9.4
gi|24664561|ref|NP_524757.1| CG6890-PA [Drosophila melanogaster]... 36 9.4
>gi|25148482|ref|NP_500157.2| cleavage polyadenylation specific factor
1 160kDa (4C774) [Caenorhabditis elegans]
gi|22096347|sp|Q9N4C2|CPSA_CAEEL Probable cleavage and
polyadenylation specificity factor, 160 kDa subunit (CPSF
160 kDa subunit)
gi|16604243|gb|AAF36067.2| Hypothetical protein Y76B12C.7
[Caenorhabditis elegans]
Length = 1454
Score = 2777 bits (7198), Expect = 0.0
Identities = 1402/1454 (96%), Positives = 1402/1454 (96%)
Frame = -1
Query: 4365 MYGYLRETDDSTAINFSAYGKFLPGENTGFQLLTIGAKFIRIFRVNPYVLKEPGEDNEEW 4186
MYGYLRETDDSTAINFSAYGKFLPGENTGFQLLTIGAKFIRIFRVNPYVLKEPGEDNEEW
Sbjct: 1 MYGYLRETDDSTAINFSAYGKFLPGENTGFQLLTIGAKFIRIFRVNPYVLKEPGEDNEEW 60
Query: 4185 QQKTKLECMFSCRLLNKCHSIAVARVPQLPDQDSILMTFDDAKLSIVSINEKERNMQTIS 4006
QQKTKLECMFSCRLLNKCHSIAVARVPQLPDQDSILMTFDDAKLSIVSINEKERNMQTIS
Sbjct: 61 QQKTKLECMFSCRLLNKCHSIAVARVPQLPDQDSILMTFDDAKLSIVSINEKERNMQTIS 120
Query: 4005 LHAFENEYLRDGFINHFQPPLVRSDPSNRCAACLVYGKHIAILPFHENSKRIHSYVIPLK 3826
LHAFENEYLRDGFINHFQPPLVRSDPSNRCAACLVYGKHIAILPFHENSKRIHSYVIPLK
Sbjct: 121 LHAFENEYLRDGFINHFQPPLVRSDPSNRCAACLVYGKHIAILPFHENSKRIHSYVIPLK 180
Query: 3825 QIDPRLDNIADMVFLDGYYEPTILFLYEPIQTTPGRACVRYDTMCIMGVSVNIVDRQFAV 3646
QIDPRLDNIADMVFLDGYYEPTILFLYEPIQTTPGRACVRYDTMCIMGVSVNIVDRQFAV
Sbjct: 181 QIDPRLDNIADMVFLDGYYEPTILFLYEPIQTTPGRACVRYDTMCIMGVSVNIVDRQFAV 240
Query: 3645 VWQTANLPMDCSQLLPIPKPLGGALVFGSNTVVYLNQAVPPCGLVLNSCYDGFTKFPLKD 3466
VWQTANLPMDCSQLLPIPKPLGGALVFGSNTVVYLNQAVPPCGLVLNSCYDGFTKFPLKD
Sbjct: 241 VWQTANLPMDCSQLLPIPKPLGGALVFGSNTVVYLNQAVPPCGLVLNSCYDGFTKFPLKD 300
Query: 3465 LKHLKMTLDCSTSVYMEDGRIAVGSRDGDLFLLRLMTSSGGGTVKSLEFSKVYETSIAYS 3286
LKHLKMTLDCSTSVYMEDGRIAVGSRDGDLFLLRLMTSSGGGTVKSLEFSKVYETSIAYS
Sbjct: 301 LKHLKMTLDCSTSVYMEDGRIAVGSRDGDLFLLRLMTSSGGGTVKSLEFSKVYETSIAYS 360
Query: 3285 LTVCAPGHLFVGSRLGDSQLLEYTLLKTTRDCAVKRLKIDNKDPAAAEIELDEDDMELYG 3106
LTVCAPGHLFVGSRLGDSQLLEYTLLKTTRDCAVKRLKIDNKDPAAAEIELDEDDMELYG
Sbjct: 361 LTVCAPGHLFVGSRLGDSQLLEYTLLKTTRDCAVKRLKIDNKDPAAAEIELDEDDMELYG 420
Query: 3105 GAXXXXXXXXXXXXXESLQFRELDRLRNVGPVKSMCVGRPNYMSNDLVDAKRRDPVFDLV 2926
GA ESLQFRELDRLRNVGPVKSMCVGRPNYMSNDLVDAKRRDPVFDLV
Sbjct: 421 GAIEEQQNDDDEQIDESLQFRELDRLRNVGPVKSMCVGRPNYMSNDLVDAKRRDPVFDLV 480
Query: 2925 TASGHGKNGALCVHQRSLRPEIITSSLLEGAEQLWAVGRKENESHKYLIVSRVRSTXXXX 2746
TASGHGKNGALCVHQRSLRPEIITSSLLEGAEQLWAVGRKENESHKYLIVSRVRST
Sbjct: 481 TASGHGKNGALCVHQRSLRPEIITSSLLEGAEQLWAVGRKENESHKYLIVSRVRSTLILE 540
Query: 2745 XXXXXXXXXXXLFVTGEPTVAAGELSQGALAVQVTSTCIALVTDGQQMQEVHIDSNFPVI 2566
LFVTGEPTVAAGELSQGALAVQVTSTCIALVTDGQQMQEVHIDSNFPVI
Sbjct: 541 LGEELVELEEQLFVTGEPTVAAGELSQGALAVQVTSTCIALVTDGQQMQEVHIDSNFPVI 600
Query: 2565 QASIVDPYVALLTQNGRLLLYELVMEPYVQLREVDISATSFATWHATAQNLTQLTSISIY 2386
QASIVDPYVALLTQNGRLLLYELVMEPYVQLREVDISATSFATWHATAQNLTQLTSISIY
Sbjct: 601 QASIVDPYVALLTQNGRLLLYELVMEPYVQLREVDISATSFATWHATAQNLTQLTSISIY 660
Query: 2385 ADASEIMKFAAAEKSMXXXXXXXGEVSTAENAMMKKEQHEEAILLHGEDDDFLYGDEDET 2206
ADASEIMKFAAAEKSM GEVSTAENAMMKKEQHEEAILLHGEDDDFLYGDEDET
Sbjct: 661 ADASEIMKFAAAEKSMGGGGGGDGEVSTAENAMMKKEQHEEAILLHGEDDDFLYGDEDET 720
Query: 2205 IMEQNFPVENGEATIKQSNTRKRKRLGHDAIQSSRGGEQSDAIDPTRTFSSISHWLIVSH 2026
IMEQNFPVENGEATIKQSNTRKRKRLGHDAIQSSRGGEQSDAIDPTRTFSSISHWLIVSH
Sbjct: 721 IMEQNFPVENGEATIKQSNTRKRKRLGHDAIQSSRGGEQSDAIDPTRTFSSISHWLIVSH 780
Query: 2025 ENGRLSIHSLPEMEVVYQIGRFSNVPELLVDLTVXXXXXXXXXXXXXXXXXASVPTDEAE 1846
ENGRLSIHSLPEMEVVYQIGRFSNVPELLVDLTV ASVPTDEAE
Sbjct: 781 ENGRLSIHSLPEMEVVYQIGRFSNVPELLVDLTVEEEEKERKAKAQQAAKEASVPTDEAE 840
Query: 1845 QLNTEMKQLCERVLEAQIVGMGINQAHPILMAIVDEQVVLYEMFSSSNPIPGHLGISFRK 1666
QLNTEMKQLCERVLEAQIVGMGINQAHPILMAIVDEQVVLYEMFSSSNPIPGHLGISFRK
Sbjct: 841 QLNTEMKQLCERVLEAQIVGMGINQAHPILMAIVDEQVVLYEMFSSSNPIPGHLGISFRK 900
Query: 1665 LPHFICLRTSSHLNSDGKRAPFEMKINNGKRFSLIHPFERVSSVNNGVMIVGAVPTLLVY 1486
LPHFICLRTSSHLNSDGKRAPFEMKINNGKRFSLIHPFERVSSVNNGVMIVGAVPTLLVY
Sbjct: 901 LPHFICLRTSSHLNSDGKRAPFEMKINNGKRFSLIHPFERVSSVNNGVMIVGAVPTLLVY 960
Query: 1485 GAWGGMQTHQMTVDGPIKAFTPFNNENVLHGIVYMTQHKSELRIARMHPDFDYEMPYPVK 1306
GAWGGMQTHQMTVDGPIKAFTPFNNENVLHGIVYMTQHKSELRIARMHPDFDYEMPYPVK
Sbjct: 961 GAWGGMQTHQMTVDGPIKAFTPFNNENVLHGIVYMTQHKSELRIARMHPDFDYEMPYPVK 1020
Query: 1305 KIEVGRTIHHVRYLMNSDVYAVVSSIPKPSNKIWVVMNDDKQEEIHEKDENFVLPAPPKY 1126
KIEVGRTIHHVRYLMNSDVYAVVSSIPKPSNKIWVVMNDDKQEEIHEKDENFVLPAPPKY
Sbjct: 1021 KIEVGRTIHHVRYLMNSDVYAVVSSIPKPSNKIWVVMNDDKQEEIHEKDENFVLPAPPKY 1080
Query: 1125 TLNLFSSQDWAAVPNTEISFEDMEAVTACEDVALKSESTISGLETLLAMGTVNNYGEEVL 946
TLNLFSSQDWAAVPNTEISFEDMEAVTACEDVALKSESTISGLETLLAMGTVNNYGEEVL
Sbjct: 1081 TLNLFSSQDWAAVPNTEISFEDMEAVTACEDVALKSESTISGLETLLAMGTVNNYGEEVL 1140
Query: 945 VRGRIILCEVIEVVPEPDQPTSNRKIKVLFDKEQKGPVTGLCAINGLLLCGMGQKVFIWQ 766
VRGRIILCEVIEVVPEPDQPTSNRKIKVLFDKEQKGPVTGLCAINGLLLCGMGQKVFIWQ
Sbjct: 1141 VRGRIILCEVIEVVPEPDQPTSNRKIKVLFDKEQKGPVTGLCAINGLLLCGMGQKVFIWQ 1200
Query: 765 FKDNDLMGISFLDMHYYVYQLHSLRTIAIACDARESMSLIRFQEDNKAMSIASRDDRKCA 586
FKDNDLMGISFLDMHYYVYQLHSLRTIAIACDARESMSLIRFQEDNKAMSIASRDDRKCA
Sbjct: 1201 FKDNDLMGISFLDMHYYVYQLHSLRTIAIACDARESMSLIRFQEDNKAMSIASRDDRKCA 1260
Query: 585 QPPMASQLVVDGAHVGFLLSDETGNITMFNYAPEAPESNGGERLTVRAAINIGTNINAFV 406
QPPMASQLVVDGAHVGFLLSDETGNITMFNYAPEAPESNGGERLTVRAAINIGTNINAFV
Sbjct: 1261 QPPMASQLVVDGAHVGFLLSDETGNITMFNYAPEAPESNGGERLTVRAAINIGTNINAFV 1320
Query: 405 RLRGHTSLLQLNNEDEKEAIEQRMTTVFASLDGSFGFVRPLTEKSYRRLHFLQTFIGSVT 226
RLRGHTSLLQLNNEDEKEAIEQRMTTVFASLDGSFGFVRPLTEKSYRRLHFLQTFIGSVT
Sbjct: 1321 RLRGHTSLLQLNNEDEKEAIEQRMTTVFASLDGSFGFVRPLTEKSYRRLHFLQTFIGSVT 1380
Query: 225 PQIAGLHIKGSRSAKPSQPIVNGRNARNLIDGDVVEQYLHLSLYDKTDLARRLGVGRYHI 46
PQIAGLHIKGSRSAKPSQPIVNGRNARNLIDGDVVEQYLHLSLYDKTDLARRLGVGRYHI
Sbjct: 1381 PQIAGLHIKGSRSAKPSQPIVNGRNARNLIDGDVVEQYLHLSLYDKTDLARRLGVGRYHI 1440
Query: 45 IDDLMQLRRMAFYY 4
IDDLMQLRRMAFYY
Sbjct: 1441 IDDLMQLRRMAFYY 1454
>gi|39594178|emb|CAE70288.1| Hypothetical protein CBG16808
[Caenorhabditis briggsae]
Length = 1454
Score = 2364 bits (6126), Expect = 0.0
Identities = 1172/1461 (80%), Positives = 1299/1461 (88%), Gaps = 7/1461 (0%)
Frame = -1
Query: 4365 MYGYLRETDDSTAINFSAYGKFLPGENTGFQLLTIGAKFIRIFRVNPYVLKEPGEDNEEW 4186
MYGYLRETDDSTAIN+SAYGKFLPGENTGFQLLTIGAKF+RIFRVNPYVLKEPGEDNEEW
Sbjct: 1 MYGYLRETDDSTAINYSAYGKFLPGENTGFQLLTIGAKFLRIFRVNPYVLKEPGEDNEEW 60
Query: 4185 QQKTKLECMFSCRLLNKCHSIAVARVPQLPDQDSILMTFDDAKLSIVSINEKERNMQTIS 4006
QQKTKLECMFSCRLLNKC S+AVARVPQLPDQDSILMTFDDAKLSIV++NEKERNMQTIS
Sbjct: 61 QQKTKLECMFSCRLLNKCQSVAVARVPQLPDQDSILMTFDDAKLSIVAVNEKERNMQTIS 120
Query: 4005 LHAFENEYLRDGFINHFQPPLVRSDPSNRCAACLVYGKHIAILPFHENSKRIHSYVIPLK 3826
LHAFENEYLRDGF +F PP+VR+DP+NRCAA LVYGKHIAILPFHENSKRI SY+IPLK
Sbjct: 121 LHAFENEYLRDGFTTYFNPPIVRTDPANRCAASLVYGKHIAILPFHENSKRILSYIIPLK 180
Query: 3825 QIDPRLDNIADMVFLDGYYEPTILFLYEPIQTTPGRACVRYDTMCIMGVSVNIVDRQFAV 3646
QIDPRLDN+ADMVFL+GYYEPTILFLYEP+QTTPGRACVRYDTMCIMGVSVNIVDRQFAV
Sbjct: 181 QIDPRLDNVADMVFLEGYYEPTILFLYEPLQTTPGRACVRYDTMCIMGVSVNIVDRQFAV 240
Query: 3645 VWQTANLPMDCSQLLPIPKPLGGALVFGSNTVVYLNQAVPPCGLVLNSCYDGFTKFPLKD 3466
VWQTANLPMDC+ LL IPKPLGGA+VFGSNT+VYLNQAVPPCG+VLNSCYDGFTKFPLKD
Sbjct: 241 VWQTANLPMDCNSLLSIPKPLGGAVVFGSNTIVYLNQAVPPCGIVLNSCYDGFTKFPLKD 300
Query: 3465 LKHLKMTLDCSTSVYMEDGRIAVGSRDGDLFLLRLMTSSGGGTVKSLEFSKVYETSIAYS 3286
+KHLKMTLDCSTSVYMEDGRIAVGSR+GDL+LLRL+TSSGG TVKSLEFSKV +TSIA++
Sbjct: 301 MKHLKMTLDCSTSVYMEDGRIAVGSREGDLYLLRLVTSSGGATVKSLEFSKVCDTSIAFT 360
Query: 3285 LTVCAPGHLFVGSRLGDSQLLEYTLLKTTRDCAVKRLKIDNKDPAAAEIELDEDDMELYG 3106
LTVCAPGHLFVGSRLGDSQLLEYTLLK T++ A K+ +++ ++P+ EIELDEDD+ELYG
Sbjct: 361 LTVCAPGHLFVGSRLGDSQLLEYTLLKVTKESA-KKQRLEQQNPS--EIELDEDDIELYG 417
Query: 3105 GAXXXXXXXXXXXXXESLQFRELDRLRNVGPVKSMCVGRPNYMSNDLVDAKRRDPVFDLV 2926
GA ESLQFRELDRL NVGPVKSMC GRPNYMSNDL+DAKR+DPVFDLV
Sbjct: 418 GAIEMQQNDDDEQISESLQFRELDRLLNVGPVKSMCFGRPNYMSNDLIDAKRKDPVFDLV 477
Query: 2925 TASGHGKNGALCVHQRSLRPEIITSSLLEGAEQLWAVGRKENESHKYLIVSRVRSTXXXX 2746
TASGHGKNGALCVHQRS+RPEIITSSLLEGAEQLWAVGRKENESHKYLIVSRVRST
Sbjct: 478 TASGHGKNGALCVHQRSMRPEIITSSLLEGAEQLWAVGRKENESHKYLIVSRVRSTLILE 537
Query: 2745 XXXXXXXXXXXLFVTGEPTVAAGELSQGALAVQVTSTCIALVTDGQQMQEVHIDSNFPVI 2566
LFVT EPTVAAGEL QGALAVQVTSTCIALVTDGQQMQEVHIDSNFPV+
Sbjct: 538 LGEELVELEEQLFVTNEPTVAAGELLQGALAVQVTSTCIALVTDGQQMQEVHIDSNFPVV 597
Query: 2565 QASIVDPYVALLTQNGRLLLYELVMEPYVQLREVDISATSFATWHATAQNLTQLTSISIY 2386
QASIVDPYVA+LTQNGR LLYEL MEPYV LREV+++ TSFAT+ + Q TQLTS+SIY
Sbjct: 598 QASIVDPYVAVLTQNGRPLLYELAMEPYVHLREVNVNETSFATF--SEQISTQLTSVSIY 655
Query: 2385 ADASEIMKFAAAEKSMXXXXXXXGEVSTAENAMMKKEQHEEAILLHGEDDDFLYGDEDET 2206
+DAS+IMK + +KKE ++ +L+GEDDDFLYGD +E
Sbjct: 656 SDASQIMKKNTVDGRDEKPENAAENGHHVAVPKIKKEIPDDDAMLYGEDDDFLYGDAEED 715
Query: 2205 IMEQNFPVENGEATIKQSNTRKRKRLGHDAIQSSRGGEQSDAIDPTRTFSSISHWLIVSH 2026
E E+GE++ + NTRKRKRLGHDAI SSRGGEQSDAIDPTRT+SSI+HWL+V+H
Sbjct: 716 --EPMVAAESGESSTRLQNTRKRKRLGHDAIMSSRGGEQSDAIDPTRTYSSITHWLVVAH 773
Query: 2025 ENGRLSIHSLPEMEVVYQIGRFSNVPELLVDLTVXXXXXXXXXXXXXXXXXASVPT---- 1858
+NGR++IHSLP++E+VYQIGRFSNVPELLVD+TV
Sbjct: 774 DNGRITIHSLPDLELVYQIGRFSNVPELLVDMTVEEEEKEKKAKQTAAQEKEKETEKKKD 833
Query: 1857 ---DEAEQLNTEMKQLCERVLEAQIVGMGINQAHPILMAIVDEQVVLYEMFSSSNPIPGH 1687
+E +Q+N+EMK+LCE+V+EAQIVGMGINQAHP+L+AI+DE+VVLYEMF+S NP PGH
Sbjct: 834 DAKNEEDQVNSEMKKLCEKVVEAQIVGMGINQAHPVLIAIIDEEVVLYEMFASYNPQPGH 893
Query: 1686 LGISFRKLPHFICLRTSSHLNSDGKRAPFEMKINNGKRFSLIHPFERVSSVNNGVMIVGA 1507
LG++FRKLPH I LRTS ++N DGKRAPFEM++ +GKR++LIHPFER+SS+NNGVMI GA
Sbjct: 894 LGVAFRKLPHLIGLRTSPYVNIDGKRAPFEMEMEHGKRYTLIHPFERISSINNGVMIGGA 953
Query: 1506 VPTLLVYGAWGGMQTHQMTVDGPIKAFTPFNNENVLHGIVYMTQHKSELRIARMHPDFDY 1327
VPTLLVYGAWGGMQTHQMT+DG IKAFTPFNNENVLHG VYMTQ KSELRIARMHPDFDY
Sbjct: 954 VPTLLVYGAWGGMQTHQMTIDGSIKAFTPFNNENVLHGFVYMTQQKSELRIARMHPDFDY 1013
Query: 1326 EMPYPVKKIEVGRTIHHVRYLMNSDVYAVVSSIPKPSNKIWVVMNDDKQEEIHEKDENFV 1147
+MPYPVKKIEVG+T+H+VRYLMNSD+YAVVSS+PKPSNKIWVVMNDDKQEEIHEKDENFV
Sbjct: 1014 DMPYPVKKIEVGKTVHNVRYLMNSDIYAVVSSVPKPSNKIWVVMNDDKQEEIHEKDENFV 1073
Query: 1146 LPAPPKYTLNLFSSQDWAAVPNTEISFEDMEAVTACEDVALKSESTISGLETLLAMGTVN 967
LPAPPKYTLNLFSSQDWAAVPNTE FEDMEAVTA EDV LKSES GL+T LA+ TVN
Sbjct: 1074 LPAPPKYTLNLFSSQDWAAVPNTEFEFEDMEAVTAMEDVPLKSESRYGGLDTYLALATVN 1133
Query: 966 NYGEEVLVRGRIILCEVIEVVPEPDQPTSNRKIKVLFDKEQKGPVTGLCAINGLLLCGMG 787
NYGEEVLVRGRIILCEVIEVVPEP QPTSNRKIKVL+DKEQKGPVTGLCAINGLLL GMG
Sbjct: 1134 NYGEEVLVRGRIILCEVIEVVPEPGQPTSNRKIKVLYDKEQKGPVTGLCAINGLLLSGMG 1193
Query: 786 QKVFIWQFKDNDLMGISFLDMHYYVYQLHSLRTIAIACDARESMSLIRFQEDNKAMSIAS 607
QKVFIWQFKDNDLMGISFLDMHYYVYQLHS+RTIA+A DARESMSLIRFQE+NKAMSIAS
Sbjct: 1194 QKVFIWQFKDNDLMGISFLDMHYYVYQLHSIRTIALALDARESMSLIRFQEENKAMSIAS 1253
Query: 606 RDDRKCAQPPMASQLVVDGAHVGFLLSDETGNITMFNYAPEAPESNGGERLTVRAAINIG 427
RDDRKCAQ PMAS+ +VDG H+GFLLSDE GNIT+F+Y+PEAPESNGGERLTV+AAINIG
Sbjct: 1254 RDDRKCAQAPMASEFLVDGMHIGFLLSDEHGNITLFSYSPEAPESNGGERLTVKAAINIG 1313
Query: 426 TNINAFVRLRGHTSLLQLNNEDEKEAIEQRMTTVFASLDGSFGFVRPLTEKSYRRLHFLQ 247
TNINAF+R++GHTSLL ++ +E+E IEQRM T+F SLDGSFG++RPLTEKSYRRLHFLQ
Sbjct: 1314 TNINAFLRVKGHTSLLDSSSPEERENIEQRMNTIFGSLDGSFGYIRPLTEKSYRRLHFLQ 1373
Query: 246 TFIGSVTPQIAGLHIKGSRSAKPSQPIVNGRNARNLIDGDVVEQYLHLSLYDKTDLARRL 67
TFIGSVTPQIAGLHIKG+RS+KPSQPIVNGRNARNLIDGDVVEQYLHLS+YDKTDLARRL
Sbjct: 1374 TFIGSVTPQIAGLHIKGARSSKPSQPIVNGRNARNLIDGDVVEQYLHLSVYDKTDLARRL 1433
Query: 66 GVGRYHIIDDLMQLRRMAFYY 4
GVGRYHI+DDLMQLRRMA+YY
Sbjct: 1434 GVGRYHILDDLMQLRRMAYYY 1454
>gi|23503048|sp|Q10570|CPSA_HUMAN Cleavage and polyadenylation
specificity factor, 160 kDa subunit (CPSF 160 kDa
subunit)
gi|16878041|gb|AAH17232.1| Cleavage and polyadenylation specific
factor 1, 160kDa [Homo sapiens]
Length = 1443
Score = 767 bits (1980), Expect = 0.0
Identities = 479/1521 (31%), Positives = 773/1521 (50%), Gaps = 67/1521 (4%)
Frame = -1
Query: 4365 MYGYLRETDDSTAINFSAYGKFLPGENTGFQLLTIGAKFIRIFRVN--PYVLKEPGEDNE 4192
MY ++ T + FS Y F N+ L+ G + ++R+N L + E
Sbjct: 1 MYAVYKQAHPPTGLEFSMYCNFF--NNSERNLVVAGTSQLYVYRLNRDAEALTKNDRSTE 58
Query: 4191 EWQQKTKLECMFSCRLLNKCHSIAVARVPQLPDQDSILMTFDDAKLSIVSINEKERNMQT 4012
+ KLE S S+A ++ +D++L++F DAKLS+V + +++T
Sbjct: 59 GKAHREKLELAASFSFFGNVMSMASVQLAGAK-RDALLLSFKDAKLSVVEYDPGTHDLKT 117
Query: 4011 ISLHAFENEYLRDGFINHFQPPLVRSDPSNRCAACLVYGKHIAILPFH------------ 3868
+SLH FE LRDGF+ + P VR DP RCAA LVYG + +LPF
Sbjct: 118 LSLHYFEEPELRDGFVQNVHTPRVRVDPDGRCAAMLVYGTRLVVLPFRRESLAEEHEGLV 177
Query: 3867 ---ENSKRIHSYVIPLKQIDPRLDNIADMVFLDGYYEPTILFLYEPIQTTPGRACVRYDT 3697
+ S + SY+I ++ +D +L NI D+ FL GYYEPT+L L+EP QT PGR VR DT
Sbjct: 178 GEGQRSSFLPSYIIDVRALDEKLLNIIDLQFLHGYYEPTLLILFEPNQTWPGRVAVRQDT 237
Query: 3696 MCIMGVSVNIVDRQFAVVWQTANLPMDCSQLLPIPKPLGGALVFGSNTVVYLNQAVPPCG 3517
I+ +S+NI + V+W +LP DC+Q L +PKP+GG +VF N+++YLNQ+VPP G
Sbjct: 238 CSIVAISLNITQKVHPVIWSLTSLPFDCTQALAVPKPIGGVVVFAVNSLLYLNQSVPPYG 297
Query: 3516 LVLNSCYDGFTKFPLKDLKHLKMTLDCSTSVYMEDGRIAVGSRDGDLFLLRLMTSSGGGT 3337
+ LNS G T FPL+ + +++TLDC+ + ++ ++ + + G++++L L+T G +
Sbjct: 298 VALNSLTTGTTAFPLRTQEGVRITLDCAQATFISYDKMVISLKGGEIYVLTLITD-GMRS 356
Query: 3336 VKSLEFSKVYETSIAYSLTVCAPGHLFVGSRLGDSQLLEYTLLKTTRDCAVKRLKIDNKD 3157
V++ F K + + S+ PG+LF+GSRLG+S LL+YT + R D ++
Sbjct: 357 VRAFHFDKAAASVLTTSMVTMEPGYLFLGSRLGNSLLLKYTEKLQEPPASAVREAADKEE 416
Query: 3156 PAAAEIELDE----------------DDMELYGGAXXXXXXXXXXXXXESLQFRELDRLR 3025
P + + +D D++E+YG + F D +
Sbjct: 417 PPSKKKRVDATAGWSAAGKSVPQDEVDEIEVYGSEAQSGTQLA------TYSFEVCDSIL 470
Query: 3024 NVGPVKSMCVGRPNYMSNDLVDAKRRDPVFDLVTASGHGKNGALCVHQRSLRPEIITSSL 2845
N+GP + VG P ++S + ++ +P ++V SGHGKNGAL V Q+S+RP+++T+
Sbjct: 471 NIGPCANAAVGEPAFLSEEFQNSP--EPDLEIVVCSGHGKNGALSVLQKSIRPQVVTTFE 528
Query: 2844 LEGAEQLWAV---GRKENES-----------------------HKYLIVSRVRSTXXXXX 2743
L G +W V RKE E H +LI+SR ST
Sbjct: 529 LPGCYDMWTVIAPVRKEEEDNPKGEGTEQEPSTTPEADDDGRRHGFLILSREDSTMILQT 588
Query: 2742 XXXXXXXXXXLFVTGEPTVAAGELSQGALAVQVTSTCIALVTDGQQMQEVHIDSNFPVIQ 2563
F T PTV AG + VQV+ I L+ Q+ + +D P++Q
Sbjct: 589 GQEIMELDTSGFATQGPTVFAGNIGDNRYIVQVSPLGIRLLEGVNQLHFIPVDLGAPIVQ 648
Query: 2562 ASIVDPYVALLTQNGRLLLYELVMEPYVQLREVDISATSFATWHATAQNLTQLTSISIYA 2383
++ DPYV +++ G + ++ L + Y A + +++ ++ +Y
Sbjct: 649 CAVADPYVVIMSAEGHVTMFLLKSDSYGGRHH------RLALHKPPLHHQSKVITLCLYR 702
Query: 2382 DASEIMKFAAAEKSMXXXXXXXGEVSTAENAMMKKEQHEEAILLHGEDDDFLYGDEDETI 2203
D S + E + G S E + E ++++ LYGD
Sbjct: 703 DLSGMF---TTESRLGGARDELGGRSGPEAEGLGSETSPTV----DDEEEMLYGDSGSLF 755
Query: 2202 MEQNFPVENGEATIKQSNTRKRKRLGHDAIQSSRGGEQSDAIDPTRTFSSISHWLIVSHE 2023
S +++ R R + DP + +HW ++ E
Sbjct: 756 ----------------SPSKEEAR---------RSSQPPADRDPAPFRAEPTHWCLLVRE 790
Query: 2022 NGRLSIHSLPEMEVVYQIGRFSNVPELLVDLTVXXXXXXXXXXXXXXXXXASVPTDEAEQ 1843
NG + I+ LP+ +V+ + F +LVD PT + E
Sbjct: 791 NGTMEIYQLPDWRLVFLVKNFPVGQRVLVD------------------SSFGQPTTQGEA 832
Query: 1842 LNTEMKQLCERVL--EAQIVGMGINQAHPILMAIVDEQVVLYEMFSSSNPI-PGHLGISF 1672
E + E L E +V +G Q+ P L+ VD+++++YE F + + G+L + F
Sbjct: 833 RREEATRQGELPLVKEVLLVALGSRQSRPYLLVHVDQELLIYEAFPHDSQLGQGNLKVRF 892
Query: 1671 RKLPHFICLRTSSHLNSDGKRAPFEMKINNGKR--FSLIHPFERVSSVNNGVMIVGAVPT 1498
+K+PH I R S K + G R + FE + + GV I G P
Sbjct: 893 KKVPHNINFREKKPKPSKKKAEGGGAEEGAGARGRVARFRYFEDIYGYS-GVFICGPSPH 951
Query: 1497 LLVYGAWGGMQTHQMTVDGPIKAFTPFNNENVLHGIVYMTQHKSELRIARMHPDFDYEMP 1318
L+ G ++ H M +DGP+ +F PF+N N G +Y + + ELRI+ + Y+ P
Sbjct: 952 WLLVTGRGALRLHPMAIDGPVDSFAPFHNVNCPRGFLYFNR-QGELRISVLPAYLSYDAP 1010
Query: 1317 YPVKKIEVGRTIHHVRYLMNSDVYAVVSSIPKPSNKIWVVMNDDKQEEIHEKDENFVLPA 1138
+PV+KI + T H+V Y + S VYAV +S P +I + ++K+ E E+DE ++ P
Sbjct: 1011 WPVRKIPLRCTAHYVAYHVESKVYAVATSTNTPCARIPRMTGEEKEFETIERDERYIHPQ 1070
Query: 1137 PPKYTLNLFSSQDWAAVPNTEISFEDMEAVTACEDVALKSESTISGLETLLAMGTVNNYG 958
+++ L S W A+PN I ++ E VT + V+L+SE T+SGL+ +A GT G
Sbjct: 1071 QEAFSIQLISPVSWEAIPNARIELQEWEHVTCMKTVSLRSEETVSGLKGYVAAGTCLMQG 1130
Query: 957 EEVLVRGRIILCEVIEVVPEPDQPTSNRKIKVLFDKEQKGPVTGLCAINGLLLCGMGQKV 778
EEV RGRI++ +VIEVVPEP QP + K KVL++KEQKGPVT LC NG L+ +GQK+
Sbjct: 1131 EEVTCRGRILIMDVIEVVPEPGQPLTKNKFKVLYEKEQKGPVTALCHCNGHLVSAIGQKI 1190
Query: 777 FIWQFKDNDLMGISFLDMHYYVYQLHSLRTIAIACDARESMSLIRFQEDNKAMSIASRDD 598
F+W + ++L G++F+D Y++Q+ S++ +A D +S+SL+R+QE++K +S+ SRD
Sbjct: 1191 FLWSLRASELTGMAFIDTQLYIHQMISVKNFILAADVMKSISLLRYQEESKTLSLVSRDA 1250
Query: 597 RKCAQPPMASQLVVDGAHVGFLLSDETGNITMFNYAPEAPESNGGERLTVRAAINIGTNI 418
+ + +VD A +GFL+SD N+ ++ Y PEA ES GG RL RA ++G ++
Sbjct: 1251 KPL--EVYSVDFMVDNAQLGFLVSDRDRNLMVYMYLPEAKESFGGMRLLRRADFHVGAHV 1308
Query: 417 NAFVR--LRGHTSLLQLNNEDEKEAI-EQRMTTVFASLDGSFGFVRPLTEKSYRRLHFLQ 247
N F R RG T L +K + E + T FA+LDG G + P+ EK+YRRL LQ
Sbjct: 1309 NTFWRTPCRGATEGL-----SKKSVVWENKHITWFATLDGGIGLLLPMQEKTYRRLLMLQ 1363
Query: 246 TFIGSVTPQIAGLHIKGSRSAKPSQPIVNGRNARNLIDGDVVEQYLHLSLYDKTDLARRL 67
+ ++ P AGL+ + R + + RN++DG+++ +YL+LS ++++LA+++
Sbjct: 1364 NALTTMLPHHAGLNPRAFRMLHVDRRTLQNA-VRNVLDGELLNRYLYLSTMERSELAKKI 1422
Query: 66 GVGRYHIIDDLMQLRRMAFYY 4
G I+DDL++ R+ ++
Sbjct: 1423 GTTPDIILDDLLETDRVTAHF 1443
>gi|16751835|ref|NP_444423.1| cleavage and polyadenylation specific
factor 1; cleavage and polyadenylation specificity factor
1; CPSF160 [Mus musculus]
gi|17374611|sp|Q9EPU4|CPSA_MOUSE Cleavage and polyadenylation
specificity factor, 160 kDa subunit (CPSF 160 kDa
subunit)
gi|11762096|gb|AAG40326.1| cleavage and polyadenylation specificity
factor 1 [Mus musculus]
gi|38614159|gb|AAH56388.1| Cleavage and polyadenylation specific
factor 1 [Mus musculus]
Length = 1441
Score = 766 bits (1979), Expect = 0.0
Identities = 474/1522 (31%), Positives = 774/1522 (50%), Gaps = 68/1522 (4%)
Frame = -1
Query: 4365 MYGYLRETDDSTAINFSAYGKFLPGENTGFQLLTIGAKFIRIFRVN--PYVLKEPGEDNE 4192
MY ++ T + F+ Y F N+ L+ G + ++R+N L + E
Sbjct: 1 MYAVYKQAHPPTGLEFTMYCNFF--NNSERNLVVAGTSQLYVYRLNRDAEALTKNDGSTE 58
Query: 4191 EWQQKTKLECMFSCRLLNKCHSIAVARVPQLPDQDSILMTFDDAKLSIVSINEKERNMQT 4012
+ KLE + S S+A ++ +D++L++F DAKLS+V + +++T
Sbjct: 59 GKAHREKLELVASFSFFGNVMSMASVQLAGAK-RDALLLSFKDAKLSVVEYDPGTHDLKT 117
Query: 4011 ISLHAFENEYLRDGFINHFQPPLVRSDPSNRCAACLVYGKHIAILPFH------------ 3868
+SLH FE LRDGF+ + P VR DP RCAA L+YG + +LPF
Sbjct: 118 LSLHYFEEPELRDGFVQNVHTPRVRVDPDGRCAAMLIYGTRLVVLPFRRESLAEEHEGLM 177
Query: 3867 ---ENSKRIHSYVIPLKQIDPRLDNIADMVFLDGYYEPTILFLYEPIQTTPGRACVRYDT 3697
+ S + SY+I ++ +D +L NI D+ FL GYYEPT+L L+EP QT PGR VR DT
Sbjct: 178 GEGQRSSFLPSYIIDVRALDEKLLNIIDLQFLHGYYEPTLLILFEPNQTWPGRVAVRQDT 237
Query: 3696 MCIMGVSVNIVDRQFAVVWQTANLPMDCSQLLPIPKPLGGALVFGSNTVVYLNQAVPPCG 3517
I+ +S+NI + V+W +LP DC+Q L +PKP+GG ++F N+++YLNQ+VPP G
Sbjct: 238 CSIVAISLNITQKVHPVIWSLTSLPFDCTQALAVPKPIGGVVIFAVNSLLYLNQSVPPYG 297
Query: 3516 LVLNSCYDGFTKFPLKDLKHLKMTLDCSTSVYMEDGRIAVGSRDGDLFLLRLMTSSGGGT 3337
+ LNS G T FPL+ + +++TLDC+ + ++ ++ + + G++++L L+T G +
Sbjct: 298 VALNSLTTGTTAFPLRTQEGVRITLDCAQAAFISYDKMVISLKGGEIYVLTLITD-GMRS 356
Query: 3336 VKSLEFSKVYETSIAYSLTVCAPGHLFVGSRLGDSQLLEYTLLKTTRDCAVKRLKIDNKD 3157
V++ F K + + S+ PG+LF+GSRLG+S LL+YT + R D ++
Sbjct: 357 VRAFHFDKAAASVLTTSMVTMEPGYLFLGSRLGNSLLLKYTEKLQEPPASSVREAADKEE 416
Query: 3156 PAAAE--------------IELDE-DDMELYGGAXXXXXXXXXXXXXESLQFRELDRLRN 3022
P + + + DE D++E+YG + F D + N
Sbjct: 417 PPSKKKRVEPAVGWTGGKTVPQDEVDEIEVYGSEAQSGTQLA------TYSFEVCDSMLN 470
Query: 3021 VGPVKSMCVGRPNYMSNDLVDAKRRDPVFDLVTASGHGKNGALCVHQRSLRPEIITSSLL 2842
+GP + VG P ++S + ++ +P ++V SG+GKNGAL V Q+S+RP+++T+ L
Sbjct: 471 IGPCANAAVGEPAFLSEEFQNSP--EPDLEIVVCSGYGKNGALSVLQKSIRPQVVTTFEL 528
Query: 2841 EGAEQLWAV---GRKENES----------------------HKYLIVSRVRSTXXXXXXX 2737
G +W V RKE E H +LI+SR ST
Sbjct: 529 PGCYDMWTVIAPVRKEEEETPKAESTEQEPSAPKAEEDGRRHGFLILSREDSTMILQTGQ 588
Query: 2736 XXXXXXXXLFVTGEPTVAAGELSQGALAVQVTSTCIALVTDGQQMQEVHIDSNFPVIQAS 2557
F T PTV AG + VQV+ I L+ Q+ + +D P++Q +
Sbjct: 589 EIMELDTSGFATQGPTVFAGNIGDNRYIVQVSPLGIRLLEGVNQLHFIPVDLGAPIVQCA 648
Query: 2556 IVDPYVALLTQNGRLLLYELVMEPYVQLREVDISATSFATWHATAQNLTQLTSISIYADA 2377
+ DPYV +++ G + ++ L + Y A + +++ ++ +Y D
Sbjct: 649 VADPYVVIMSAEGHVTMFLLKSDSYGGRHH------RLALHKPPLHHQSKVIALCLYRDV 702
Query: 2376 SEIM----KFAAAEKSMXXXXXXXGEVSTAENAMMKKEQHEEAILLHGEDDDFLYGDEDE 2209
S + + A + E +E + ++ E +L+G+ ++E
Sbjct: 703 SGMFTTESRLGGARDELGGRSGSEAEGLGSETSPTVDDEEE---MLYGDSSALFSPSKEE 759
Query: 2208 TIMEQNFPVENGEATIKQSNTRKRKRLGHDAIQSSRGGEQSDAIDPTRTFSSISHWLIVS 2029
P + A K DPT HW ++
Sbjct: 760 ARRSSQPPADRDPAPFKA--------------------------DPT-------HWCLLV 786
Query: 2028 HENGRLSIHSLPEMEVVYQIGRFSNVPELLVDLTVXXXXXXXXXXXXXXXXXASVPTDEA 1849
ENG + I+ LP+ +V+ + F +LVD PT +
Sbjct: 787 RENGTMEIYQLPDWRLVFLVKNFPVGQRVLVD------------------SSFGQPTTQG 828
Query: 1848 EQLNTEMKQLCERVL--EAQIVGMGINQAHPILMAIVDEQVVLYEMFSSSNPI-PGHLGI 1678
E E + E L E +V +G Q+ P L+ VD+++++YE F + + G+L +
Sbjct: 829 EVRKEEATRQGELPLVKEVLLVALGSRQSRPYLLVHVDQELLIYEAFPHDSQLGQGNLKV 888
Query: 1677 SFRKLPHFICLRTSSHLNSDGKRAPFEMKINNGKR--FSLIHPFERVSSVNNGVMIVGAV 1504
F+K+PH I R S K + +G R + FE + + GV I G
Sbjct: 889 RFKKVPHNINFREKKPKPSKKKAEGCSTEEGSGGRGRVARFRYFEDIYGYS-GVFICGPS 947
Query: 1503 PTLLVYGAWGGMQTHQMTVDGPIKAFTPFNNENVLHGIVYMTQHKSELRIARMHPDFDYE 1324
P L+ G ++ H M +DGPI +F PF+N N G +Y + + ELRI+ + Y+
Sbjct: 948 PHWLLVTGRGALRLHPMGIDGPIDSFAPFHNVNCPRGFLYFNR-QGELRISVLPAYLSYD 1006
Query: 1323 MPYPVKKIEVGRTIHHVRYLMNSDVYAVVSSIPKPSNKIWVVMNDDKQEEIHEKDENFVL 1144
P+PV+KI + T H+V Y + S VYAV +S P +I + ++K+ E E+D+ ++
Sbjct: 1007 APWPVRKIPLRCTAHYVAYHVESKVYAVATSTNTPCTRIPRMTGEEKEFEAIERDDRYIH 1066
Query: 1143 PAPPKYTLNLFSSQDWAAVPNTEISFEDMEAVTACEDVALKSESTISGLETLLAMGTVNN 964
P +++ L S W A+PN I E+ E VT + V+L+SE T+SGL+ +A GT
Sbjct: 1067 PQQEAFSIQLISPVSWEAIPNARIELEEWEHVTCMKTVSLRSEETVSGLKGYVAAGTCLM 1126
Query: 963 YGEEVLVRGRIILCEVIEVVPEPDQPTSNRKIKVLFDKEQKGPVTGLCAINGLLLCGMGQ 784
GEEV RGRI++ +VIEVVPEP QP + K KVL++KEQKGPVT LC NG L+ +GQ
Sbjct: 1127 QGEEVTCRGRILIMDVIEVVPEPGQPLTKNKFKVLYEKEQKGPVTALCHCNGHLVSAIGQ 1186
Query: 783 KVFIWQFKDNDLMGISFLDMHYYVYQLHSLRTIAIACDARESMSLIRFQEDNKAMSIASR 604
K+F+W + ++L G++F+D Y++Q+ S++ +A D +S+SL+R+QE++K +S+ SR
Sbjct: 1187 KIFLWSLRASELTGMAFIDTQLYIHQMISVKNFILAADVMKSISLLRYQEESKTLSLVSR 1246
Query: 603 DDRKCAQPPMASQLVVDGAHVGFLLSDETGNITMFNYAPEAPESNGGERLTVRAAINIGT 424
D + + +VD A +GFL+SD N+ ++ Y PEA ES GG RL RA ++G
Sbjct: 1247 DAKPL--EVYSVDFMVDNAQLGFLVSDRDRNLMVYMYLPEAKESFGGMRLLRRADFHVGA 1304
Query: 423 NINAFVRLRGHTSLLQLNNEDEKEAI--EQRMTTVFASLDGSFGFVRPLTEKSYRRLHFL 250
++N F R T K+++ E + T FA+LDG G + P+ EK+YRRL L
Sbjct: 1305 HVNTFWR----TPCRGAAEGPSKKSVVWENKHITWFATLDGGIGLLLPMQEKTYRRLLML 1360
Query: 249 QTFIGSVTPQIAGLHIKGSRSAKPSQPIVNGRNARNLIDGDVVEQYLHLSLYDKTDLARR 70
Q + ++ P AGL+ + R + I+ RN++DG+++ +YL+LS ++++LA++
Sbjct: 1361 QNALTTMLPHHAGLNPRAFRMLHVDRRILQNA-VRNVLDGELLNRYLYLSTMERSELAKK 1419
Query: 69 LGVGRYHIIDDLMQLRRMAFYY 4
+G I+DDL++ R+ ++
Sbjct: 1420 IGTTPDIILDDLLETDRVTAHF 1441
>gi|27807297|ref|NP_777145.1| cleavage and polyadenylation specific
factor 1, 160kDa [Bos taurus]
gi|1706101|sp|Q10569|CPSA_BOVIN Cleavage and polyadenylation
specificity factor, 160 kDa subunit (CPSF 160 kDa
subunit)
gi|1363024|pir||S57335 cleavage and polyadenylation specificity
factor 160K chain - bovine
gi|929007|emb|CAA58152.1| cleavage and polyadenylation specificity
factor, 160 kDa subunit [Bos taurus]
Length = 1444
Score = 763 bits (1971), Expect = 0.0
Identities = 470/1531 (30%), Positives = 767/1531 (49%), Gaps = 77/1531 (5%)
Frame = -1
Query: 4365 MYGYLRETDDSTAINFSAYGKFLPGENTGFQLLTIGAKFIRIFRVN-----PYVLKEPGE 4201
MY ++ T + FS Y F N+ L+ G + ++R+N P +
Sbjct: 1 MYAVYKQAHPPTGLEFSMYCNFF--NNSERNLVVAGTSQLYVYRLNRDSEAPTKNDRSTD 58
Query: 4200 DNEEWQQKTKLECMFSCRLLNKCHSIAVARVPQLPDQDSILMTFDDAKLSIVSINEKERN 4021
+ + KLE + S S+A ++ +D++L++F DAKLS+V + +
Sbjct: 59 GKAHREHREKLELVASFSFFGNVMSMASVQLAGAK-RDALLLSFKDAKLSVVEYDPGTHD 117
Query: 4020 MQTISLHAFENEYLRDGFINHFQPPLVRSDPSNRCAACLVYGKHIAILPFH--------- 3868
++T+SLH FE LRDGF+ + P VR DP RCAA L+YG + +LPF
Sbjct: 118 LKTLSLHYFEEPELRDGFVQNVHTPRVRVDPDGRCAAMLIYGTRLVVLPFRRESLAEEHE 177
Query: 3867 ------ENSKRIHSYVIPLKQIDPRLDNIADMVFLDGYYEPTILFLYEPIQTTPGRACVR 3706
+ S + SY+I ++ +D +L NI D+ FL GYYEPT+L L+EP QT PGR VR
Sbjct: 178 GLVGEGQRSSFLPSYIIDVRALDEKLLNIVDLQFLHGYYEPTLLILFEPNQTWPGRVAVR 237
Query: 3705 YDTMCIMGVSVNIVDRQFAVVWQTANLPMDCSQLLPIPKPLGGALVFGSNTVVYLNQAVP 3526
DT I+ +S+NI + V+W +LP DC+Q L +PKP+GG ++F N+++YLNQ+VP
Sbjct: 238 QDTCSIVAISLNITQKVHPVIWSLTSLPFDCTQALAVPKPIGGVVIFAVNSLLYLNQSVP 297
Query: 3525 PCGLVLNSCYDGFTKFPLKDLKHLKMTLDCSTSVYMEDGRIAVGSRDGDLFLLRLMTSSG 3346
P G+ LNS G T FPL+ + +++TLDC+ + ++ ++ + + G++++L L+T G
Sbjct: 298 PYGVALNSLTTGTTAFPLRTQEGVRITLDCAQAAFISYDKMVISLKGGEIYVLTLITD-G 356
Query: 3345 GGTVKSLEFSKVYETSIAYSLTVCAPGHLFVGSRLGDSQLLEYTLLKTTRDCAVKRLKID 3166
+V++ F K + + S+ PG+LF+GSRLG+S LL+YT + R D
Sbjct: 357 MRSVRAFHFDKAAASVLTTSMVTMEPGYLFLGSRLGNSLLLKYTEKLQEPPASTAREAAD 416
Query: 3165 NKDPAAAEIELDE---------------DDMELYGGAXXXXXXXXXXXXXESLQFRELDR 3031
++P + + +D D++E+YG + F D
Sbjct: 417 KEEPPSKKKRVDATTGWSGSKSVPQDEVDEIEVYGSEAQSGTQLA------TYSFEVCDS 470
Query: 3030 LRNVGPVKSMCVGRPNYMSNDLVDAKRRDPVFDLVTASGHGKNGALCVHQRSLRPEIITS 2851
+ N+GP + +G P ++S + ++ +P ++V SG+GKNGAL V Q+S+RP+++T+
Sbjct: 471 ILNIGPCANAAMGEPAFLSEEFQNSP--EPDLEIVVCSGYGKNGALSVLQKSIRPQVVTT 528
Query: 2850 SLLEGAEQLWAV---GRKENES----------------------HKYLIVSRVRSTXXXX 2746
L G +W V RKE E H +LI+SR ST
Sbjct: 529 FELPGCYDMWTVIAPVRKEQEETLKGEGTEPEPGAPEAEDDGRRHGFLILSREDSTMILQ 588
Query: 2745 XXXXXXXXXXXLFVTGEPTVAAGELSQGALAVQVTSTCIALVTDGQQMQEVHIDSNFPVI 2566
F T PTV AG + VQV+ I L+ Q+ + +D P++
Sbjct: 589 TGQEIMELDASGFATQGPTVFAGNIGDNRYIVQVSPLGIRLLEGVNQLHFIPVDLGSPIV 648
Query: 2565 QASIVDPYVALLTQNGRLLLYELVMEPYVQLREVDISATSFATWHATAQNLTQLTSISIY 2386
Q ++ DPYV +++ G + ++ L + Y A + +++ ++ +Y
Sbjct: 649 QCAVADPYVVIMSAEGHVTMFLLKNDSYGGRHH------RLALHKPPLHHQSKVITLCVY 702
Query: 2385 ADASEIM----KFAAAEKSMXXXXXXXGEVSTAENAMMKKEQHEEAILLHGEDDDFLYGD 2218
D S + + + E AE + ++ E +L+G+
Sbjct: 703 RDVSGMFTTESRLGGVRDELGGRGGPEAEGQGAETSPTVDDEEE---MLYGDSGSLFSPS 759
Query: 2217 EDETIMEQNFPVENGEATIKQSNTRKRKRLGHDAIQSSRGGEQSDAIDPTRTFSSISHWL 2038
++E P + A + T HW
Sbjct: 760 KEEARRSSQPPADRDPAPFRAEPT---------------------------------HWC 786
Query: 2037 IVSHENGRLSIHSLPEMEVVYQIGRFSNVPELLVDLTVXXXXXXXXXXXXXXXXXASVPT 1858
++ ENG + I+ LP+ +V+ + F +LVD PT
Sbjct: 787 LLVRENGAMEIYQLPDWRLVFLVKNFPVGQRVLVD------------------SSFGQPT 828
Query: 1857 DEAEQLNTEMKQLCERVL--EAQIVGMGINQAHPILMAIVDEQVVLYEMFSSSNPI-PGH 1687
+ E E + E L E +V +G Q P L+ VD+++++YE F + + G+
Sbjct: 829 TQGEARKEEATRQGELPLVKEVLLVALGSRQRRPYLLVHVDQELLIYEAFPHDSQLGQGN 888
Query: 1686 LGISFRKLPHFICLRTSSHLNSDGKRAPFEMKINNGKRFSLIHPFERVSSVN-------- 1531
L + F+K+PH I R + K P + K G P RV+
Sbjct: 889 LKVRFKKVPHNINFR-------EKKPKPSKKKAEGGSTEEGTGPRGRVARFRYFEDIYGY 941
Query: 1530 NGVMIVGAVPTLLVYGAWGGMQTHQMTVDGPIKAFTPFNNENVLHGIVYMTQHKSELRIA 1351
+GV I G P L+ G ++ H M +DGPI +F PF+N N G +Y + + ELRI+
Sbjct: 942 SGVFICGPSPHWLLVTGRGALRLHPMGIDGPIDSFAPFHNINCPRGFLYFNR-QGELRIS 1000
Query: 1350 RMHPDFDYEMPYPVKKIEVGRTIHHVRYLMNSDVYAVVSSIPKPSNKIWVVMNDDKQEEI 1171
+ Y+ P+PV+KI + T H+V Y + S VYAV +S P ++ + ++K+ E
Sbjct: 1001 VLPAYLSYDAPWPVRKIPLRCTAHYVAYHVESKVYAVATSTSTPCTRVPRMTGEEKEFET 1060
Query: 1170 HEKDENFVLPAPPKYTLNLFSSQDWAAVPNTEISFEDMEAVTACEDVALKSESTISGLET 991
E+DE +V P + + L S W A+PN I E+ E VT + V+L+SE T+SGL+
Sbjct: 1061 IERDERYVHPQQEAFCIQLISPVSWEAIPNARIELEEWEHVTCMKTVSLRSEETVSGLKG 1120
Query: 990 LLAMGTVNNYGEEVLVRGRIILCEVIEVVPEPDQPTSNRKIKVLFDKEQKGPVTGLCAIN 811
+A GT GEEV RGRI++ +VIEVVPEP QP + K KVL++KEQKGPVT LC N
Sbjct: 1121 YVAAGTCLMQGEEVTCRGRILIMDVIEVVPEPGQPLTKNKFKVLYEKEQKGPVTALCHCN 1180
Query: 810 GLLLCGMGQKVFIWQFKDNDLMGISFLDMHYYVYQLHSLRTIAIACDARESMSLIRFQED 631
G L+ +GQK+F+W + ++L G++F+D Y++Q+ S++ +A D +S+SL+R+QE+
Sbjct: 1181 GHLVSAIGQKIFLWSLRASELTGMAFIDTQLYIHQMISVKNFILAADVMKSISLLRYQEE 1240
Query: 630 NKAMSIASRDDRKCAQPPMASQLVVDGAHVGFLLSDETGNITMFNYAPEAPESNGGERLT 451
+K +S+ SRD + + +VD A +GFL+SD N+ ++ Y PEA ES GG RL
Sbjct: 1241 SKTLSLVSRDAKPL--EVYSVDFMVDNAQLGFLVSDRDRNLMVYMYLPEAKESFGGMRLL 1298
Query: 450 VRAAINIGTNINAFVRLRGHTSLLQLNNEDEKEAI--EQRMTTVFASLDGSFGFVRPLTE 277
RA ++G ++N F R T K+++ E + T FA+LDG G + P+ E
Sbjct: 1299 RRADFHVGAHVNTFWR----TPCRGAAEGPSKKSVVWENKHITWFATLDGGIGLLLPMQE 1354
Query: 276 KSYRRLHFLQTFIGSVTPQIAGLHIKGSRSAKPSQPIVNGRNARNLIDGDVVEQYLHLSL 97
K+YRRL LQ + ++ P AGL+ + R + ++ RN++DG+++ +YL+LS
Sbjct: 1355 KTYRRLLMLQNALTTMLPHHAGLNPRAFRMLHVDRRVLQNA-VRNVLDGELLNRYLYLST 1413
Query: 96 YDKTDLARRLGVGRYHIIDDLMQLRRMAFYY 4
++ +LA+++G I+DDL++ R+ ++
Sbjct: 1414 MERGELAKKIGTTPDIILDDLLETDRVTAHF 1444
>gi|9558725|ref|NP_037423.1| cleavage and polyadenylation specific
factor 1, 160kDa; cleavage and polyadenylation
specificity factor; cleavage and polyadenylation specific
factor 1, 160kD subunit [Homo sapiens]
gi|1045574|gb|AAC50293.1| cleavage and polyadenylation specificity
factor
Length = 1442
Score = 763 bits (1971), Expect = 0.0
Identities = 475/1519 (31%), Positives = 769/1519 (50%), Gaps = 65/1519 (4%)
Frame = -1
Query: 4365 MYGYLRETDDSTAINFSAYGKFLPGENTGFQLLTIGAKFIRIFRVN--PYVLKEPGEDNE 4192
MY ++ + FS Y F N+ L+ G + ++R+N L + E
Sbjct: 1 MYAVYKQAHPPPGLEFSMYCNFF--NNSERNLVVAGTSQLYVYRLNRDAEALTKNDRSTE 58
Query: 4191 EWQQKTKLECMFSCRLLNKCHSIAVARVPQLPDQDSILMTFDDAKLSIVSINEKERNMQT 4012
+ KLE S S+A ++ +D++L++F DAKLS+V + +++T
Sbjct: 59 GKAHREKLELAASFSFFGNVMSMASVQLAGAK-RDALLLSFKDAKLSVVEYDPGTHDLKT 117
Query: 4011 ISLHAFENEYLRDGFINHFQPPLVRSDPSNRCAACLVYGKHIAILPFH------------ 3868
+SLH FE LRDGF+ + P VR DP RCAA LVYG + +LPF
Sbjct: 118 LSLHYFEEPELRDGFVQNVHTPRVRVDPDGRCAAMLVYGTRLVVLPFRRESLAEEHEGLV 177
Query: 3867 ---ENSKRIHSYVIPLKQIDPRLDNIADMVFLDGYYEPTILFLYEPIQTTPGRACVRYDT 3697
+ S + SY+I ++ +D +L NI D+ FL GYYEPT+L L+EP QT PGR VR DT
Sbjct: 178 GEGQRSSFLPSYIIDVRALDEKLLNIIDLQFLHGYYEPTLLILFEPNQTWPGRVAVRQDT 237
Query: 3696 MCIMGVSVNIVDRQFAVVWQTANLPMDCSQLLPIPKPLGGALVFGSNTVVYLNQAVPPCG 3517
I+ +S+NI + V+W +LP DC+Q L +PKP+GG +VF N+++YLNQ+VPP G
Sbjct: 238 CSIVAISLNITQKVHPVIWSLTSLPFDCTQALAVPKPIGGVVVFAVNSLLYLNQSVPPYG 297
Query: 3516 LVLNSCYDGFTKFPLKDLKHLKMTLDCSTSVYMEDGRIAVGSRDGDLFLLRLMTSSGGGT 3337
+ LNS G T FPL+ + +++TLDC+ + ++ ++ + + G++++L L+T G +
Sbjct: 298 VALNSLTTGTTAFPLRTQEGVRITLDCAQATFISYDKMVISLKGGEIYVLTLITD-GMRS 356
Query: 3336 VKSLEFSKVYETSIAYSLTVCAPGHLFVGSRLGDSQLLEYTLLKTTRDCAVKRLKIDNKD 3157
V++ F K + + S+ PG+LF+GSRLG+S LL+YT + R D ++
Sbjct: 357 VRAFHFDKAAASVLTTSMVTMEPGYLFLGSRLGNSLLLKYTEKLQEPPASAVREAADKEE 416
Query: 3156 PAAAEIELDE----------------DDMELYGGAXXXXXXXXXXXXXESLQFRELDRLR 3025
P + + +D D++E+YG + F D +
Sbjct: 417 PPSKKKRVDATAGWSAAGKSVPQDEVDEIEVYGSEAQSGTQLA------TYSFEVCDSIL 470
Query: 3024 NVGPVKSMCVGRPNYMSNDLVDAKRRDPVFDLVTASGHGKNGALCVHQRSLRPEIITSSL 2845
N+GP + VG P ++S + ++ +P ++V SGHGKNGAL V Q+S+RP+++T+
Sbjct: 471 NIGPCANAAVGEPAFLSEEFQNSP--EPDLEIVVCSGHGKNGALSVLQKSIRPQVVTTFE 528
Query: 2844 LEGAEQLWAV---GRKENES-----------------------HKYLIVSRVRSTXXXXX 2743
L G +W V RKE E H +LI+SR ST
Sbjct: 529 LPGCYDMWTVIAPVRKEEEDNPKGEGTEQEPSTTPEADDDGRRHGFLILSREDSTMILQT 588
Query: 2742 XXXXXXXXXXLFVTGEPTVAAGELSQGALAVQVTSTCIALVTDGQQMQEVHIDSNFPVIQ 2563
F T PTV AG + VQV+ I L+ Q+ + +D P++Q
Sbjct: 589 GQEIMELDTSGFATQGPTVFAGNIGDNRYIVQVSPLGIRLLEGVNQLHFIPVDLGAPIVQ 648
Query: 2562 ASIVDPYVALLTQNGRLLLYELVMEPYVQLREVDISATSFATWHATAQNLTQLTSISIYA 2383
++ DPYV +++ G + ++ L + Y A + +++ ++ +Y
Sbjct: 649 CAVADPYVVIMSAEGHVTMFLLKSDSYGGRHH------RLALHKPPLHHQSKVITLCLYR 702
Query: 2382 DASEIMKFAAAEKSMXXXXXXXGEVSTAENAMMKKEQHEEAILLHGEDDDFLYGDEDETI 2203
D S + E + G S E + E ++++ LYGD
Sbjct: 703 DLSGMF---TTESRLGGARDELGGRSGPEAEGLGSETSPTV----DDEEEMLYGDSGSLF 755
Query: 2202 MEQNFPVENGEATIKQSNTRKRKRLGHDAIQSSRGGEQSDAIDPTRTFSSISHWLIVSHE 2023
S +++ R R + DP + +HW ++ E
Sbjct: 756 ----------------SPSKEEAR---------RSSQPPADRDPAPFRAEPTHWCLLVRE 790
Query: 2022 NGRLSIHSLPEMEVVYQIGRFSNVPELLVDLTVXXXXXXXXXXXXXXXXXASVPTDEAEQ 1843
NG + I+ LP+ +V+ + F +LVD PT + E
Sbjct: 791 NGTMEIYQLPDWRLVFLVKNFPVGQRVLVD------------------SSFGQPTTQGEA 832
Query: 1842 LNTEMKQLCERVL--EAQIVGMGINQAHPILMAIVDEQVVLYEMFSSSNPI-PGHLGISF 1672
E + E L E +V +G Q+ P L+ VD+++++YE F + + G+L + F
Sbjct: 833 RREEATRQGELPLVKEVLLVALGSRQSRPYLLVHVDQELLIYEAFPHDSQLGQGNLKVRF 892
Query: 1671 RKLPHFICLRTSSHLNSDGKRAPFEMKINNGKR--FSLIHPFERVSSVNNGVMIVGAVPT 1498
+K+PH I R S K + G R + FE + + GV I G P
Sbjct: 893 KKVPHNINFREKKPKPSKKKAEGGGAEEGAGARGRVARFRYFEDIYGYS-GVFICGPSPH 951
Query: 1497 LLVYGAWGGMQTHQMTVDGPIKAFTPFNNENVLHGIVYMTQHKSELRIARMHPDFDYEMP 1318
L+ G ++ H M +DGP+ +F PF+N N G +Y + + ELRI+ + Y+ P
Sbjct: 952 WLLVTGRGALRLHPMAIDGPVDSFAPFHNVNCPRGFLYFNR-QGELRISVLPAYLSYDAP 1010
Query: 1317 YPVKKIEVGRTIHHVRYLMNSDVYAVVSSIPKPSNKIWVVMNDDKQEEIHEKDENFVLPA 1138
+PV+KI + T H+V Y + S VYAV +S P +I + ++K+ E E+DE ++ P
Sbjct: 1011 WPVRKIPLRCTAHYVAYHVESKVYAVATSTNTPCARIPRMTGEEKEFETIERDERYIHPQ 1070
Query: 1137 PPKYTLNLFSSQDWAAVPNTEISFEDMEAVTACEDVALKSESTISGLETLLAMGTVNNYG 958
+++ L S W A+PN I ++ E VT + V+L+SE T+SGL+ +A GT G
Sbjct: 1071 QEAFSIQLISPVSWEAIPNARIELQEWEHVTCMKTVSLRSEETVSGLKGYVAAGTCLMQG 1130
Query: 957 EEVLVRGRIILCEVIEVVPEPDQPTSNRKIKVLFDKEQKGPVTGLCAINGLLLCGMGQKV 778
EEV RGRI++ +VIEVVPEP QP + K KVL++KEQKGPVT LC NG L+ +GQK+
Sbjct: 1131 EEVTCRGRILIMDVIEVVPEPGQPLTKNKFKVLYEKEQKGPVTALCHCNGHLVSAIGQKI 1190
Query: 777 FIWQFKDNDLMGISFLDMHYYVYQLHSLRTIAIACDARESMSLIRFQEDNKAMSIASRDD 598
F+W + ++L G++F+D Y++Q+ S++ +A D +S+SL+R+QE++K +S+ SRD
Sbjct: 1191 FLWSLRASELTGMAFIDTQLYIHQMISVKNFILAADVMKSISLLRYQEESKTLSLVSRDA 1250
Query: 597 RKCAQPPMASQLVVDGAHVGFLLSDETGNITMFNYAPEAPESNGGERLTVRAAINIGTNI 418
+ + +VD A +GFL+SD N+ ++ Y PEA ES GG RL RA ++G ++
Sbjct: 1251 KPL--EVYSVDFMVDNAQLGFLVSDRDRNLMVYMYLPEAKESFGGMRLLRRADFHVGAHV 1308
Query: 417 NAFVRLRGHTSLLQLNNEDEKEAI-EQRMTTVFASLDGSFGFVRPLTEKSYRRLHFLQTF 241
N F R T +K + E + T FA+LDG G + P+ EK+YRRL LQ
Sbjct: 1309 NTFWR----TPCRATEGLSKKSVVWENKHITWFATLDGGIGLLLPMQEKTYRRLLMLQNA 1364
Query: 240 IGSVTPQIAGLHIKGSRSAKPSQPIVNGRNARNLIDGDVVEQYLHLSLYDKTDLARRLGV 61
+ ++ P AGL+ + R + + RN++DG+++ +YL+LS ++++LA+++G
Sbjct: 1365 LTTMLPHHAGLNPRAFRMLHVDRRTLQNA-VRNVLDGELLNRYLYLSTMERSELAKKIGT 1423
Query: 60 GRYHIIDDLMQLRRMAFYY 4
I+DDL++ R+ ++
Sbjct: 1424 TPDIILDDLLETDRVTAHF 1442
>gi|34867012|ref|XP_345850.1| similar to cleavage and polyadenylation
specificity factor 1 [Rattus norvegicus]
Length = 1437
Score = 762 bits (1967), Expect = 0.0
Identities = 471/1520 (30%), Positives = 772/1520 (49%), Gaps = 66/1520 (4%)
Frame = -1
Query: 4365 MYGYLRETDDSTAINFSAYGKFLPGENTGFQLLTIGAKFIRIFRVN--PYVLKEPGEDNE 4192
MY ++ T + F+ Y F N+ L+ G + ++R+N L + E
Sbjct: 1 MYAVYKQAHPPTGLEFAMYCNFF--NNSERNLVVAGTSQLYVYRLNRDAEALTKNDGSTE 58
Query: 4191 EWQQKTKLECMFSCRLLNKCHSIAVARVPQLPDQDSILMTFDDAKLSIVSINEKERNMQT 4012
+ KLE + S S+A ++ +D++L++F DAKLS+V + +++T
Sbjct: 59 GKAHREKLELVASFSFFGNVMSMASVQLAGAK-RDALLLSFKDAKLSVVEYDPGTHDLKT 117
Query: 4011 ISLHAFENEYLRDGFINHFQPPLVRSDPSNRCAACLVYGKHIAILPFH------------ 3868
+SLH FE LRDGF+ + P VR DP RCAA L+YG + +LPF
Sbjct: 118 LSLHYFEEPELRDGFVQNVHTPRVRVDPDGRCAAMLIYGTRLVVLPFRRESLAEEHEGLM 177
Query: 3867 ---ENSKRIHSYVIPLKQIDPRLDNIADMVFLDGYYEPTILFLYEPIQTTPGRACVRYDT 3697
+ S + SY+I ++ +D +L NI D+ FL GYYEPT+L L+EP QT PGR VR DT
Sbjct: 178 GEGQRSSFLPSYIIDVRALDEKLLNIIDLQFLHGYYEPTLLILFEPNQTWPGRVAVRQDT 237
Query: 3696 MCIMGVSVNIVDRQFAVVWQTANLPMDCSQLLPIPKPLGGALVFGSNTVVYLNQAVPPCG 3517
I+ +S+NI + V+W +LP DC+Q L +PKP+GG ++F N+++YLNQ+VPP G
Sbjct: 238 CSIVAISLNITQKVHPVIWSLTSLPFDCTQALAVPKPIGGVVIFAVNSLLYLNQSVPPYG 297
Query: 3516 LVLNSCYDGFTKFPLKDLKHLKMTLDCSTSVYMEDGRIAVGSRDGDLFLLRLMTSSGGGT 3337
+ LNS G T FPL+ + +++TLDC+ + ++ ++ + + G++++L L+T G +
Sbjct: 298 VALNSLTTGTTAFPLRTQEGVRITLDCAQAAFISYDKMVISLKGGEIYVLTLITD-GMRS 356
Query: 3336 VKSLEFSKVYETSIAYSLTVCAPGHLFVGSRLGDSQLLEYTLLKTTRDCAVKRLKIDNKD 3157
V++ F K + + S+ PG+LF+GSRLG+S LL+YT + R D ++
Sbjct: 357 VRAFHFDKAAASVLTTSMVTMEPGYLFLGSRLGNSLLLKYTEKLQEPPASSVREAADKEE 416
Query: 3156 PAAAEIELDE-------------DDMELYGGAXXXXXXXXXXXXXESLQFRELDRLRNVG 3016
P + + +D D++E+YG + F D + N+G
Sbjct: 417 PPSKKKRVDPTVGWTGGKTQDEVDEIEVYGSEAQSGTQLA------TYSFEVCDSMLNIG 470
Query: 3015 PVKSMCVGRPNYMSNDLVDAKRRDPVFDLVTASGHGKNGALCVHQRSLRPEIITSSLLEG 2836
P + VG P ++S + ++ +P ++V SG+GKNGAL V Q+S+RP+++T+ L G
Sbjct: 471 PCANAAVGEPAFLSEEFQNSP--EPDLEIVVCSGYGKNGALSVLQKSIRPQVVTTFELPG 528
Query: 2835 AEQLWAV---GRKENES----------------------HKYLIVSRVRSTXXXXXXXXX 2731
+W V RKE E H +LI+SR ST
Sbjct: 529 CYDMWTVIAPVRKEEEETPKAESTEQEPSAPKAEEDGRRHGFLILSREDSTMILQTGQEI 588
Query: 2730 XXXXXXLFVTGEPTVAAGELSQGALAVQVTSTCIALVTDGQQMQEVHIDSNFPVIQASIV 2551
F T PTV AG + VQV+ I L+ Q+ + +D P++Q ++
Sbjct: 589 MELDTSGFATQGPTVFAGNIGDNRYIVQVSPLGIRLLEGVNQLHFIPVDLGAPIVQCAVA 648
Query: 2550 DPYVALLTQNGRLLLYELVMEPYVQLREVDISATSFATWHATAQNLTQLTSISIYADASE 2371
DPYV +++ G + ++ L + Y A + +++ ++ +Y D S
Sbjct: 649 DPYVVIMSAEGHVTMFLLKSDSYGGRHH------RLALHKPPLHHQSKVIALCLYRDVSG 702
Query: 2370 IM----KFAAAEKSMXXXXXXXGEVSTAENAMMKKEQHEEAILLHGEDDDFLYGDEDETI 2203
+ + A + E +E + ++ E +L+G+ ++E
Sbjct: 703 MFTTESRLGGARDELGGRSGSEAEGLGSETSPTVDDEEE---MLYGDSSSLFSPSKEEAR 759
Query: 2202 MEQNFPVENGEATIKQSNTRKRKRLGHDAIQSSRGGEQSDAIDPTRTFSSISHWLIVSHE 2023
P + A + DPT HW ++ E
Sbjct: 760 RSNQPPADRDPAPFRA--------------------------DPT-------HWCLLVRE 786
Query: 2022 NGRLSIHSLPEMEVVYQIGRFSNVPELLVDLTVXXXXXXXXXXXXXXXXXASVPTDEAEQ 1843
NG + I+ LP+ +V+ + F +LVD PT + E
Sbjct: 787 NGTMEIYQLPDWRLVFLVKNFPVGQRVLVD------------------SSFGQPTTQGEV 828
Query: 1842 LNTEMKQLCERVL--EAQIVGMGINQAHPILMAIVDEQVVLYEMFSSSNPI-PGHLGISF 1672
E + E L E +V +G Q+ P L+ VD+++++YE F + + G+L + F
Sbjct: 829 RKEEATRQGELPLVKEVLLVALGSRQSRPYLLVHVDQELLIYEAFPHDSQLGQGNLKVRF 888
Query: 1671 RKLPHFICLRTSSHLNSDGKRAPFEMKINNGKR--FSLIHPFERVSSVNNGVMIVGAVPT 1498
+K+PH I R S K + +G R + FE + + GV I G P
Sbjct: 889 KKVPHNINFREKKPKPSKKKAEGCSTEEGSGVRGRVARFRYFEDIYGYS-GVFICGPSPH 947
Query: 1497 LLVYGAWGGMQTHQMTVDGPIKAFTPFNNENVLHGIVYMTQHKSELRIARMHPDFDYEMP 1318
L+ G ++ H M +DGPI +F PF+N N G +Y + + ELRI+ + Y+ P
Sbjct: 948 WLLVTGRGALRLHPMGIDGPIDSFAPFHNVNCPRGFLYFNR-QGELRISVLPAYLSYDAP 1006
Query: 1317 YPVKKIEVGRTIHHVRYLMNSDVYAVVSSIPKPSNKIWVVMNDDKQEEIHEKDENFVLPA 1138
+PV+KI + T H+V Y + S VYAV +S P +I + ++K+ E E+D+ ++ P
Sbjct: 1007 WPVRKIPLRCTAHYVAYHVESKVYAVATSTNTPCTRIPRMTGEEKEFEAIERDDRYIHPQ 1066
Query: 1137 PPKYTLNLFSSQDWAAVPNTEISFEDMEAVTACEDVALKSESTISGLETLLAMGTVNNYG 958
+++ L S W A+PN I E+ E VT + V+L+SE T+SGL+ +A GT G
Sbjct: 1067 QEAFSIQLISPVSWEAIPNARIELEEWEHVTCMKTVSLRSEETVSGLKGYVAAGTCLMQG 1126
Query: 957 EEVLVRGRIILCEVIEVVPEPDQPTSNRKIKVLFDKEQKGPVTGLCAINGLLLCGMGQKV 778
EEV RGRI++ +VIEVVPEP QP + K KVL++KEQKGPVT LC NG L+ +GQK+
Sbjct: 1127 EEVTCRGRILIMDVIEVVPEPGQPLTKNKFKVLYEKEQKGPVTALCHCNGHLVSAIGQKI 1186
Query: 777 FIWQFKDNDLMGISFLDMHYYVYQLHSLRTIAIACDARESMSLIRFQEDNKAMSIASRDD 598
F+W + ++L G++F+D Y++Q+ S++ +A D +S+SL+R+QE++K +S+ SRD
Sbjct: 1187 FLWSLRASELTGMAFIDTQLYIHQMISVKNFILAADVMKSISLLRYQEESKTLSLVSRDA 1246
Query: 597 RKCAQPPMASQLVVDGAHVGFLLSDETGNITMFNYAPEAPESNGGERLTVRAAINIGTNI 418
+ + +VD A +GFL+SD N+ ++ Y PE ES GG RL RA ++G ++
Sbjct: 1247 KPL--EVYSVDFMVDNAQLGFLVSDRDRNLMVYMYLPE--ESFGGMRLLRRADFHVGAHV 1302
Query: 417 NAFVRLRGHTSLLQLNNEDEKEAI--EQRMTTVFASLDGSFGFVRPLTEKSYRRLHFLQT 244
N F R T K+++ E + T FA+LDG G + P+ EK+YRRL LQ
Sbjct: 1303 NTFWR----TPCRGAAEGPSKKSVMWENKHITWFATLDGGIGLLLPMQEKTYRRLLMLQN 1358
Query: 243 FIGSVTPQIAGLHIKGSRSAKPSQPIVNGRNARNLIDGDVVEQYLHLSLYDKTDLARRLG 64
+ ++ P AGL+ + R + I+ RN++DG+++ +YL+LS ++++LA+++G
Sbjct: 1359 ALTTMLPHHAGLNPRAFRMLHVDRRILQNA-VRNVLDGELLNRYLYLSTMERSELAKKIG 1417
Query: 63 VGRYHIIDDLMQLRRMAFYY 4
I+DDL++ R+ ++
Sbjct: 1418 TTPDIILDDLLETDRVTAHF 1437
>gi|47217773|emb|CAG05995.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1446
Score = 719 bits (1856), Expect = 0.0
Identities = 476/1544 (30%), Positives = 785/1544 (50%), Gaps = 90/1544 (5%)
Frame = -1
Query: 4365 MYGYLRETDDSTAINFSAYGKFLPGENTGFQLLTIGAKFIRIFRVNPYV--LKEPGEDNE 4192
MY R+ TA+ FS Y F+ + L+ G + ++R+ V + + ++
Sbjct: 1 MYAVYRQAHTPTAVEFSVYCNFISSKEKN--LVVAGTSQLFVYRIIHDVESTSKTDKSSD 58
Query: 4191 EWQQKTKLECMFSCRLLNKCHSIAVARVPQLPDQDSILMTFDDAKLSIVSINEKERNMQT 4012
+K KLE + + L S+ ++ ++D++L++F DAKLS+V + +++T
Sbjct: 59 SKTRKEKLEQVAAFSLFGNVMSMESVQLVGA-NRDALLLSFKDAKLSVVEYDPGTHDLKT 117
Query: 4011 ISLHAFENEYLRDGFINHFQPPLVRSDPSNRCAACLVYGKHIAILPFHENSKRIHSYVIP 3832
+SLH FE LRD + Q V P + + LP +Y+I
Sbjct: 118 LSLHYFEEPELRDTLTDE-QELGVGEGPKS------------SFLP---------TYIID 155
Query: 3831 LKQIDPRLDNIADMVFLDGYYEPTILFLYEPIQTTPGRACVRYDTMCIMGVSVNIVDRQF 3652
++++D +L NI DM FL GYYEPT+L L+EP QT PGR VR I+ +S+NI+ +
Sbjct: 156 VRELDEKLLNIIDMKFLHGYYEPTLLILFEPNQTWPGRVAVRQAQCSIVAISLNIMQKVH 215
Query: 3651 AVVWQTANLPMDCSQLLPIPKPLGGALVFGSNTVVYLNQAVPPCGLVLNSCYDGFTKFPL 3472
V+W +NLP DC+Q++ +PKP+GG +VF N+++YLNQ+VPP G+ LNS +G T FPL
Sbjct: 216 PVIWSLSNLPFDCTQVMAVPKPIGGVVVFAVNSLLYLNQSVPPYGVALNSLTNGTTAFPL 275
Query: 3471 KDLKHLKMTLDCSTSVYMEDGRIAVGSRDGDLFLLRLMTSSGGGTVKSLEFSKVYETSIA 3292
+ +K+TLDCS + ++ ++ + + G++++L L+T G +V++ F K + +
Sbjct: 276 RLQDEVKITLDCSQADFIAYDKMVISLKGGEIYVLTLITD-GMRSVRAFHFDKAAASVLT 334
Query: 3291 YSLTVCAPGHLFVGSRLGDSQLLEYTL------LKTTRDCAVKRLKID----------NK 3160
+ PG+LF+GSRLG+S LL+YT L+ +D K D N
Sbjct: 335 TCMVTMEPGYLFLGSRLGNSLLLKYTEKLQEMPLEEGKDKQEKEKDNDMDKQVYVHTLNS 394
Query: 3159 DPAAAEIE--LDE-DDMELYGGAXXXXXXXXXXXXXESLQFRELDRLRNVGPVKSMCVGR 2989
A ++ + +DE D++E+YG + F D + N+GP + +G
Sbjct: 395 FSAHSQHDFFVDEVDEIEVYGSEAQSGTQLA------TYSFEVCDSILNIGPCANASMGE 448
Query: 2988 PNYMSNDLVDAKRRDPVFDLVTASGHGKNGALCVHQRSLRPEIITSSLLEGAEQLWAVGR 2809
P ++S + +P ++V SGHGKNGAL V QRS+RP+++T+ L G +W V
Sbjct: 449 PAFLSEEFQG--NPEPDLEVVVCSGHGKNGALSVLQRSIRPQVVTTFELPGCHDMWTVIS 506
Query: 2808 KE------------------------NESHKYLIVSRVRSTXXXXXXXXXXXXXXXLFVT 2701
E + H +LI+SR ST F T
Sbjct: 507 NEVKEDKKVPQSPGSFTATHYSLEEDTKKHGFLILSREDSTMILQTGQEIMELDTSGFAT 566
Query: 2700 GEPTVAAGELSQGALAVQVTSTCIALVTDGQQMQEVHIDSNFPVIQASIVDPYVALLTQN 2521
PTV AG + +QV+ I L+ +Q+ + +D P++ S+ DPYV ++T
Sbjct: 567 QGPTVFAGNIGDNKYIIQVSPMGIRLLEGVKQLHFIPVDLGSPIVHCSVADPYVVIMTAE 626
Query: 2520 GRLLLYELVMEPYVQLREVDISATSFATWHATAQNLTQLTSISIYADASEIMKFAAAEKS 2341
G + ++ L ++ Y+ A +++ ++ Y D S + F K
Sbjct: 627 GVVTMFVLKVDSYMG------KTHRLALQKPQISTQSRVIALCAYRDVSGM--FTTENK- 677
Query: 2340 MXXXXXXXGEVSTAENAMMKKEQHEEAIL------LHGEDDDFLYGDEDETIMEQNFPVE 2179
+ AE+ ++ + E ++ + ++++ LYGD
Sbjct: 678 --------VSCAIAEDFNIRSQSETETVIHDLSSNIVDDEEEMLYGDSS----------- 718
Query: 2178 NGEATIKQSNTRKRKRLGHDAIQSSRGGEQSDAIDPTRTFSSISHWLIVSHENGRLSIHS 1999
+ K+ R G S GG + SHW +V+ E+G + I+
Sbjct: 719 SNAGPSKEEMIRSFVAPGPSV---SEGGPSK---------AEPSHWCLVTRESGVMEIYQ 766
Query: 1998 LPEMEVVYQIGRFSNVPELLVDLTVXXXXXXXXXXXXXXXXXASVPTDEAEQLNTEMKQL 1819
LP+ +V+ + F +LVD S + E EM +
Sbjct: 767 LPDWRLVFLVKNFPVGQRVLVD----------------SSSGQSATQGDKEGKKEEMTRQ 810
Query: 1818 CE--RVLEAQIVGMGINQAHPILMAIVDEQVVLYEMFSSSNPIP-GHLGISFRKLPHFIC 1648
E V E +V +G N + P L+ V++++++YE F P +L + F+K+PH I
Sbjct: 811 GEIPLVKEVTLVSLGYNHSRPYLLVHVEQELLVYEAFPYDQQQPQNNLKVRFKKVPHNIN 870
Query: 1647 LRTS-SHLNSDGKR--APFEMKINNGKRFSLIHPFERVSSVNNGVMIVGAVPTLLVYGAW 1477
R S L D K A E + R S FE +S + GV I G P ++ +
Sbjct: 871 FREKKSKLRKDKKAEGAAAEDGVAARGRISRFRYFEDISGYS-GVFICGPSPHWMLVTSR 929
Query: 1476 GGMQTHQMTVDGPIKAFTPFNNENVLHGIVYMTQHKSELRIARMHPDFDYEMPYPVKKIE 1297
G ++ H MT+DGPI++F+PF+N N G +Y + + ELRI+ + Y+ P+PV+KI
Sbjct: 930 GALRLHPMTIDGPIESFSPFHNINCPKGFLYFNK-QGELRISVLPTYLSYDAPWPVRKIP 988
Query: 1296 VGRTIHHVRYLMNSD-------VYAVVSSIPKPSNKIWVVMNDDKQEEIHEKDENFVLPA 1138
+ T+H+V Y + S VYAV +S+ + +I + ++K+ E E+DE ++ P
Sbjct: 989 LRCTVHYVSYHVESKASLSHCCVYAVCTSVKELCTRIPRMTGEEKEYETIERDERYINPQ 1048
Query: 1137 PPKYTLNLFSSQDWAAVPNTEISFEDMEAVTACEDVALKSESTISGLETLLAMGTVNNYG 958
K+++ L S W A+PNT I E+ E VT + VAL+S+ T+SGL+ +A GT G
Sbjct: 1049 QDKFSIQLISPVSWEAIPNTRIDLEEWEYVTCMKTVALRSQETVSGLKGYIAAGTCLMQG 1108
Query: 957 EEVLVRGRIILCEVIEVVPEPDQPTSNRKIKVLFDKEQKGPVTGLCAINGLLLCGMGQKV 778
EEV RGRI++ +VIEVVPEP QP + K KVL++KEQKGPVT LC NG L+ +GQK+
Sbjct: 1109 EEVTCRGRILILDVIEVVPEPGQPLTKNKFKVLYEKEQKGPVTALCHCNGYLVSAIGQKI 1168
Query: 777 FIWQFKDNDLMGISFLDMHYYVYQLHSLRTIAIACDARESMSLIRFQEDNKAMSIASRDD 598
F+W KDNDL G++F+D Y++Q+ S++ +A D +S+SL+R+QE++K +S+ SRD
Sbjct: 1169 FLWVLKDNDLTGMAFIDTQLYIHQMMSIKNFILAADLMKSVSLLRYQEESKTLSLVSRDA 1228
Query: 597 RKCAQPPMASQLVVDGAHVGFLLSDETGNITMFNYAPEAPESNGGERLTVRAAINIGTNI 418
+ + + +VD + +GFL+SD N+ ++ Y PEA ES GG RL RA N G NI
Sbjct: 1229 KPL--EVYSIEFMVDNSQLGFLVSDRDKNLYVYMYLPEAKESFGGMRLLRRADFNAGANI 1286
Query: 417 NAFVRLRGHTSLLQLNNEDEKEAI--EQRMTTVFASLDGSFGFVRPLTEKSYRRLHFLQT 244
N F R+ +L ++A+ + + T FA+LDG G + P+ EK+YRRL LQ
Sbjct: 1287 NTFWRMPCRGAL----EAGSRKAMTWDNKHITWFATLDGGVGLLLPMQEKTYRRLLMLQN 1342
Query: 243 FIGSVTPQIAGLHIKGSR---SAKPSQPIVNG---------------------RNARNLI 136
+ ++ AGL+ K R + + S +++G +N++
Sbjct: 1343 ALTTMLSHHAGLNPKAFRCVGADRTSAAMLSGMLPDFATSVSRMLHCDRRSLQNPVKNIL 1402
Query: 135 DGDVVEQYLHLSLYDKTDLARRLGVGRYHIIDDLMQLRRMAFYY 4
DG+++ +YL+LS+ ++++LA+++G + I+DDL+ + R+ ++
Sbjct: 1403 DGELLNKYLYLSMMERSELAKKIGTTQDIILDDLLDIDRVTAHF 1446
>gi|45552619|ref|NP_995833.1| CG10110-PA [Drosophila melanogaster]
gi|18203551|sp|Q9V726|CPSA_DROME Cleavage and polyadenylation
specificity factor, 160 kDa subunit (CPSF 160 kDa
subunit) (CPSF-160) (dCPSF)
gi|7303176|gb|AAF58240.1| CG10110-PA [Drosophila melanogaster]
Length = 1455
Score = 696 bits (1795), Expect = 0.0
Identities = 457/1533 (29%), Positives = 760/1533 (48%), Gaps = 82/1533 (5%)
Frame = -1
Query: 4365 MYGYLRETDDSTAINFSAYGKFLPGENTGFQLLTIGAKFIRIFRVNPYV----LKEPGED 4198
M+ ++T +TA+ FS +F N L+ GA ++++R+ P V ++
Sbjct: 1 MFSMCKQTHSATAVEFSIACRFF--NNLDENLVVAGANVLKVYRIAPNVEASQRQKLNPS 58
Query: 4197 NEEWQQKTKLECMFSCRLLN-----KCHSIAVARVPQLPDQDSILMTFDDAKLSIVSINE 4033
K +LEC+ + L +C S+A A +D++L++F DAKLS++ +
Sbjct: 59 EMRLAPKMRLECLATYTLYGNVMSLQCVSLAGAM------RDALLISFKDAKLSVLQHDP 112
Query: 4032 KERNMQTISLHAFENEYLRDGFINHFQPPLVRSDPSNRCAACLVYGKHIAILPFHENSKR 3853
++T+SLH FE + +R G+ + P VR DP +RCA LVYGK + +LPF +++
Sbjct: 113 DTFALKTLSLHYFEEDDIRGGWTGRYFVPTVRVDPDSRCAVMLVYGKRLVVLPFRKDNSL 172
Query: 3852 ------------------------IHSYVIPLKQIDPRLDNIADMVFLDGYYEPTILFLY 3745
+ SY+I L+ +D ++DN+ D+ FL GYYEPT+L LY
Sbjct: 173 DEIELADVKPIKKAPTAMVSRTPIMASYLIALRDLDEKIDNVLDIQFLHGYYEPTLLILY 232
Query: 3744 EPIQTTPGRACVRYDTMCIMGVSVNIVDRQFAVVWQTANLPMDCSQLLPIPKPLGGALVF 3565
EP++T PGR VR DT ++ +S+NI R ++W +LP DC Q+ PI KP+GG LV
Sbjct: 233 EPVRTCPGRIKVRSDTCVLVAISLNIQQRVHPIIWTVNSLPFDCLQVYPIQKPIGGCLVM 292
Query: 3564 GSNTVVYLNQAVPPCGLVLNSCYDGFTKFPLKDLKHLKMTLDCSTSVYMEDGRIAVGSRD 3385
N V+YLNQ+VPP G+ LNS D T FPLK ++++LDC+ +++ ++ + R
Sbjct: 293 TVNAVIYLNQSVPPYGVSLNSSADNSTAFPLKPQDGVRISLDCANFAFIDVDKLVISLRT 352
Query: 3384 GDLFLLRLMTSSGGGTVKSLEFSKVYETSIAYSLTVCAPGHLFVGSRLGDSQLLEY---- 3217
GDL++L L S TV++ F K + + + V ++F+GSRLG+S LL +
Sbjct: 353 GDLYVLTLCVDS-MRTVRNFHFHKAAASVLTSCICVLHSEYIFLGSRLGNSLLLHFTEED 411
Query: 3216 -----TLLKTTRDCAVKRLKIDNKDPAAAEI----------------ELDEDDMELYGGA 3100
TL + + ++ + ++D EI ++++++E+YG
Sbjct: 412 QSTVITLDEVEQQSEQQQRNLQDEDQNLEEIFDVDQLEMAPTQAKSRRIEDEELEVYGSG 471
Query: 3099 XXXXXXXXXXXXXESLQFRELDRLRNVGPVKSMCVGRPNYMSNDLVDAK-----RRDPVF 2935
F D L NV P+ MC G D V + +D
Sbjct: 472 -----AKASVLQLRKFIFEVCDSLMNVAPINYMCAGERVEFEEDGVTLRPHAESLQDLKI 526
Query: 2934 DLVTASGHGKNGALCVHQRSLRPEIITSSLLEGAEQLWAV------GRKENESHKYLIVS 2773
+LV A+GH KNGAL V + P+IITS L+G +W V N+ H ++++S
Sbjct: 527 ELVAATGHSKNGALSVFVNCINPQIITSFELDGCLDVWTVFDDATKKSSRNDQHDFMLLS 586
Query: 2772 RVRSTXXXXXXXXXXXXXXXLFVTGEPTVAAGELSQGALAVQVTSTCIALVTDGQQMQEV 2593
+ ST F +PT+ G L Q VQVT+ + L+ + +Q V
Sbjct: 587 QRNSTLVLQTGQEINEIENTGFTVNQPTIFVGNLGQQRFIVQVTTRHVRLLQGTRLIQNV 646
Query: 2592 HIDSNFPVIQASIVDPYVALLTQNGRLLLYELVMEPYVQLREVDISATSFATWHATAQNL 2413
ID PV+Q SI DPYV L NG+++ + LRE + H T +
Sbjct: 647 PIDVGSPVVQVSIADPYVCLRVLNGQVIT--------LALRETRGTPRLAINKH-TISSS 697
Query: 2412 TQLTSISIYADASEIMKFAAAEKSMXXXXXXXGEVSTAENAMMKKEQHEEAILLHGEDDD 2233
+ +IS Y D S + F + + MK E + + +++D
Sbjct: 698 PAVVAISAYKDLSGL--FTVKGDDINLTGSSNSAFGHSFGGYMKAEPNMKV----EDEED 751
Query: 2232 FLYGDEDETIMEQNFPVENGEATIKQSNTRKRKRLGHDAIQSSRGGEQSDAIDPTRTFSS 2053
LYGD F + + KQS + +Q+
Sbjct: 752 LLYGDAGSA-----FKMNSMADLAKQSKQKNSDWWRRLLVQAKP---------------- 790
Query: 2052 ISHWLIVSHENGRLSIHSLPEMEVVYQIGRFSNVPELLVDLTVXXXXXXXXXXXXXXXXX 1873
S+WL+V+ ++G L I+S+P+M++VY + N +L D
Sbjct: 791 -SYWLVVARQSGTLEIYSMPDMKLVYLVNDVGNGSMVLTD------------------AM 831
Query: 1872 ASVPTDEAEQLNTE--MKQLC-------ERVLEAQIVGMGINQAHPILMAIVDEQVVLYE 1720
VP Q N++ + Q C LE ++G+G+N P+L+ ++++Y+
Sbjct: 832 EFVPISLTTQENSKAGIVQACMPQHANSPLPLELSVIGLGLNGERPLLLVRTRVELLIYQ 891
Query: 1719 MFSSSNPIPGHLGISFRKLPHFICL---RTSSHLNSDGKRAPFEMKINNGKRFSLIHPFE 1549
+F GHL I FRK+ L T L+ + ++ E K + PF
Sbjct: 892 VFRYPK---GHLKIRFRKMDQLNLLDQQPTHIDLDENDEQEEIESYQMQPKYVQKLRPFA 948
Query: 1548 RVSSVNNGVMIVGAVPTLLVYGAWGGMQTHQMTVDGPIKAFTPFNNENVLHGIVYMTQHK 1369
V + +GVM+ G P + G ++ H++ +G +++F FNN N+ +G +Y
Sbjct: 949 NVGGL-SGVMVCGVNPCFVFLTFRGELRIHRLLGNGDVRSFAAFNNVNIPNGFLYF-DTT 1006
Query: 1368 SELRIARMHPDFDYEMPYPVKKIEVGRTIHHVRYLMNSDVYAVVSSIPKPSNKIWVVMND 1189
EL+I+ + Y+ +PV+K+ + T + Y + VY +++ +P K + +
Sbjct: 1007 YELKISVLPSYLSYDSVWPVRKVPLRCTPRQLVYHRENRVYCLITQTEEPMTKYYRFNGE 1066
Query: 1188 DKQEEIHEKDENFVLPAPPKYTLNLFSSQDWAAVPNTEISFEDMEAVTACEDVALKSEST 1009
DK+ + E F+ P ++ + L S + W VP+ I+FE E VTA + V L E T
Sbjct: 1067 DKELSEESRGERFIYPIGSQFEMVLISPETWEIVPDASITFEPWEHVTAFKIVKLSYEGT 1126
Query: 1008 ISGLETLLAMGTVNNYGEEVLVRGRIILCEVIEVVPEPDQPTSNRKIKVLFDKEQKGPVT 829
SGL+ L +GT NY E++ RG I + ++IEVVPEP +P + KIK +F KEQKGPV+
Sbjct: 1127 RSGLKEYLCIGTNFNYSEDITSRGNIHIYDIIEVVPEPGKPMTKFKIKEIFKKEQKGPVS 1186
Query: 828 GLCAINGLLLCGMGQKVFIWQFKDNDLMGISFLDMHYYVYQLHSLRTIAIACDARESMSL 649
+ + G L+ G+GQK++IWQ +D DL+G++F+D + YV+Q+ +++++ D +S+SL
Sbjct: 1187 AISDVLGFLVTGLGQKIYIWQLRDGDLIGVAFIDTNIYVHQIITVKSLIFIADVYKSISL 1246
Query: 648 IRFQEDNKAMSIASRDDRKCAQPPMASQLVVDGAHVGFLLSDETGNITMFNYAPEAPESN 469
+RFQE+ + +S+ASRD + +VD +++GFL++D NI ++ Y PEA ES
Sbjct: 1247 LRFQEEYRTLSLASRDFNPL--EVYGIEFMVDNSNLGFLVTDAERNIIVYMYQPEARESL 1304
Query: 468 GGERLTVRAAINIGTNINAFVRLRGHTSLLQLNNEDEKEAIEQRMTTVFASLDGSFGFVR 289
GG++L +A ++G +N R++ H L ++ + E + V+ +LDG+ G+
Sbjct: 1305 GGQKLLRKADYHLGQVVNTMFRVQCHQKGL---HQRQPFLYENKHFVVYGTLDGALGYCL 1361
Query: 288 PLTEKSYRRLHFLQTFIGSVTPQIAGLHIKGSRSAKPSQPIVNGRN-ARNLIDGDVVEQY 112
PL EK YRR LQ + S + GL+ K R+ K S+ G N +R +IDGD++ Y
Sbjct: 1362 PLPEKVYRRFLMLQNVLLSYQEHLCGLNPKEYRTLKSSKK--QGINPSRCIIDGDLIWSY 1419
Query: 111 LHLSLYDKTDLARRLGVGRYHIIDDLMQLRRMA 13
++ ++ ++A+++G I+ DL+++ R+A
Sbjct: 1420 RLMANSERNEVAKKIGTRTEEILGDLLEIERLA 1452
>gi|31200727|ref|XP_309311.1| ENSANGP00000018461 [Anopheles gambiae]
gi|21293116|gb|EAA05261.1| ENSANGP00000018461 [Anopheles gambiae str.
PEST]
Length = 1452
Score = 678 bits (1750), Expect = 0.0
Identities = 471/1537 (30%), Positives = 769/1537 (49%), Gaps = 87/1537 (5%)
Frame = -1
Query: 4365 MYGYLRETDDSTAINFSAYGKFLPGENTGFQLLTIGAKFIRIFRVNPYVLKEPGEDNEEW 4186
M+ ++ ++TA+ FS F + L+T GA ++++RV P +P ++
Sbjct: 1 MFSLCKQPHEATAVEFSLTCHFF--NHNEKSLVTGGANVLKVYRVIPDA--DPATRDKYT 56
Query: 4185 QQKT---KLECMFSCRLLNKCHSI-AVARVPQLPDQDSILMTFDDAKLSIVSINEKERNM 4018
+ KLEC+ S RL S+ +V+ L +D++L++F DAKLS+V + ++
Sbjct: 57 AARPPNMKLECVASYRLNGNIKSMQSVSLAGSL--RDALLISFPDAKLSVVQFDPDNFDL 114
Query: 4017 QTISLHAFENEYLRDGFINHFQPPLVRSDPSNRCAACLVYGKHIAILPFHENSKR----- 3853
+T+SLH FE+E +R G+ H+ P+VR DP NRCA LVYG+ + +LPF ++S
Sbjct: 115 KTLSLHYFEDEDIRGGWTGHYHIPMVRVDPDNRCAVMLVYGRKLVVLPFRKDSSLDEIEL 174
Query: 3852 -------------------IHSYVIPLKQIDPRLDNIADMVFLDGYYEPTILFLYEPIQT 3730
+ SY+I LK +D ++DN+ D+ FL GYYEPT+L LYEP++T
Sbjct: 175 QDVKPIKKAPMQLVAKTPILASYIIELKDLDEKIDNVIDIQFLHGYYEPTLLILYEPVRT 234
Query: 3729 TPGRACVRYDTMCIMGVSVNIVDRQFAVVWQTANLPMDCSQLLPIPKPLGGALVFGSNTV 3550
PGR VR DT ++ +S+NI R V+W +LP DC Q +PI KP+GG LV N++
Sbjct: 235 FPGRIAVRSDTCTMVALSLNIQQRVHPVIWTVNSLPFDCIQAIPINKPIGGCLVMCVNSL 294
Query: 3549 VYLNQAVPPCGLVLNSCYDGFTKFPLKDLKHLKMTLDCSTSVYMEDGRIAVGSRDGDLFL 3370
+YLNQ+VPP G+ LNS D T FPLK ++++LD + ++E ++ + + G+L++
Sbjct: 295 IYLNQSVPPYGVSLNSSADHSTSFPLKPQDGVRISLDAAQVCFIEPEKLVLSLKGGELYV 354
Query: 3369 LRLMTSSGGGTVKSLEFSKVYETSIAYSLTVCAPGHLFVGSRLGDSQLLEYTLLKTTRDC 3190
L L S +V++ F+K + + + VC +LF+GSRLG+S LL + +D
Sbjct: 355 LTLCADS-MRSVRNFHFNKAAASVLTSCICVCEDEYLFLGSRLGNSLLLRF----KEKD- 408
Query: 3189 AVKRLKIDNKDPAAAEIE-----LDEDDMELYGGAXXXXXXXXXXXXXESLQFRELDRLR 3025
+ L I D A E E L+E+++E+YG S F D +
Sbjct: 409 --ESLVITIDDSGAVEKEPKRPRLEEEELEVYGSG------YKTSVQLTSYIFEVCDNVL 460
Query: 3024 NVGPVKSMCVG----RPNYMSNDLVDAKRRDPVFDLVTASGHGKNGALCVHQRSLRPEII 2857
N+GP+ M VG + + V + ++VT+SGHGKNGALCV Q S++P++I
Sbjct: 461 NIGPIAHMAVGERVAEEDAENQPDVQIVQNKLDIEVVTSSGHGKNGALCVLQSSIKPQVI 520
Query: 2856 TSSLLEGAEQLW-----AVGRKENE---SHKYLIVSRVRSTXXXXXXXXXXXXXXXLFVT 2701
TS L G +W AV R+ + +H ++I+S+ T F T
Sbjct: 521 TSFGLSGCVDVWTVFDEAVARRAEDGPSTHAFMILSQEGGTMVLQTGEEINEIENTGFAT 580
Query: 2700 GEPTVAAGELSQGALAVQVTSTCIALVTDGQQMQEVHIDSNFPVIQASIVDPYVALLTQN 2521
PT+ G + VQVT+ I L+ + +Q + ID P+ +IVDPYV + +
Sbjct: 581 TVPTIHVGNIGTNRFIVQVTTKSIRLLQGTRLLQNIPIDLGCPLASVAIVDPYVCVRSSE 640
Query: 2520 GR---LLLYELVMEPYVQLREVDISATSFATWHATAQNLTQLTSISIYADASEIMKFAAA 2350
GR L L E P + + + IS T + +IS Y D S +
Sbjct: 641 GRVITLALREGKGTPRLAVNKNTISPT------------PAVVAISAYRDVSGLFT-KKI 687
Query: 2349 EKSMXXXXXXXGEVSTAENAMMKKEQHEEAILLHGEDDDFLYGDEDETIMEQNFPVENGE 2170
E ++ MK E H + +++D LYG+ +
Sbjct: 688 EDVYDLSRGGAASAYSSGFGSMKPEPHMKI----EDEEDLLYGESGRSF----------- 732
Query: 2169 ATIKQSNTRKRKRLGHDAIQSSRGG------EQSDAIDPTRTFSSISHWLIVSHENGRLS 2008
K + AI GG + + PT +WL + +NG L
Sbjct: 733 ---------KMTSMADMAIAGKSGGSADFWMKYMQQVKPT-------YWLFAARDNGTLE 776
Query: 2007 IHSLPEMEVVYQIGRFSNVPELLVDLTVXXXXXXXXXXXXXXXXXASVPTDEAEQLNTEM 1828
I+S+P++++VY I N ++L D S ++A
Sbjct: 777 IYSMPDLKLVYLITNVGNGNKVLSD----------SMEFVPLPMGKSASQEDASSAFGAS 826
Query: 1827 KQLCERVLEAQI--VGMGINQAHPILMAIVDEQVVLYEMFSSSNPIPGHLGISFRKLPHF 1654
+ +L +I V +G + P+L ++ +++Y +F S GHL + F++L
Sbjct: 827 FGVSASLLPKEILMVALGSYGSRPLLFIRLEHDLLIYRVFRYSK---GHLKLRFKRLSTS 883
Query: 1653 I---CLRT--SSHLNSDGKRAPFEMKINNG---------------------KRFSLIHPF 1552
+ RT + N D K A + + S+I F
Sbjct: 884 VTCPVFRTVPARFANLDSKTAAGGTEPEPSGAGATEAANEQQQARATKVLYENISMIRYF 943
Query: 1551 ERVSSVNNGVMIVGAVPTLLVYGAWGGMQTHQMTVDGPIKAFTPFNNENVLHGIVYMTQH 1372
VS GV + G P L A G +++H++ +KAF PFNN N +G +Y +
Sbjct: 944 ANVSGY-AGVAVCGEKPYFLFLTAHGELRSHRLYARTVMKAFAPFNNVNCPNGFLYFDE- 1001
Query: 1371 KSELRIARMHPDFDYEMPYPVKKIEVGRTIHHVRYLMNSDVYAVVSSIPKPSNKIWVVMN 1192
+ EL+I+ Y+ +PV+KI + + + Y + VY VV + NK +
Sbjct: 1002 QYELKISIFPTYLSYDSVWPVRKIPLRSSPKQIVYHRENKVYCVVMDAEEICNKYYRFNG 1061
Query: 1191 DDKQEEIHEKDENFVLPAPPKYTLNLFSSQDWAAVPNTEISFEDMEAVTACEDVALKSES 1012
+DK+ K E F+ P ++++ L + W VP T I+ E+ E V A ++V+L E
Sbjct: 1062 EDKELTEENKGERFLYPMGHRFSVVLVTPAAWEVVPETSINLEEWEHVIALKNVSLTYEG 1121
Query: 1011 TISGLETLLAMGTVNNYGEEVLVRGRIILCEVIEVVPEPDQPTSNRKIKVLFDKEQKGPV 832
SGL+ +A+GT NY E++ RGR++L ++IEVVPEP +P + K K + K+QKGPV
Sbjct: 1122 ARSGLKEYIAVGTNFNYSEDITSRGRLLLYDIIEVVPEPGKPLTKHKFKEVIVKDQKGPV 1181
Query: 831 TGLCAINGLLLCGMGQKVFIWQFKDNDLMGISFLDMHYYVYQLHSLRTIAIACDARESMS 652
+ + + G L+ +GQKV++WQ KD+DL+G++F+D + +V+Q+ S++++ + D +S+S
Sbjct: 1182 SAISHVCGFLVGAVGQKVYLWQMKDDDLVGVAFIDTNIFVHQMVSIKSLILVADVYKSVS 1241
Query: 651 LIRFQEDNKAMSIASRDDRKCAQPPMASQLVVDGAHVGFLLSDETGNITMFNYAPEAPES 472
L+RFQE+ + +S+ SRD + VVD A++GFL+SD+ N+ + Y PE+ ES
Sbjct: 1242 LLRFQEEYRTLSVVSRDYHPL--NVFQVEYVVDNANLGFLVSDDQCNLITYMYQPESRES 1299
Query: 471 NGGERLTVRAAINIGTNINAFVRLR---GHTSLLQLN-NEDEKEAIEQRMTTVFASLDGS 304
GG+RL ++ ++G +N R++ T +++ N D K TT FA+LDG
Sbjct: 1300 FGGQRLLRKSDYHLGQQVNCMFRVQCDFHETDVMKRTLNYDNKH------TTFFATLDGG 1353
Query: 303 FGFVRPLTEKSYRRLHFLQTFIGSVTPQIAGLHIKGSRSAKPSQPI-VNGRNARNLIDGD 127
GFV PL EK+YRRL LQ + + +P GL+ K R+ K ++ + +N +R ++DGD
Sbjct: 1354 IGFVLPLPEKTYRRLFMLQNVLLTHSPHTCGLNPKAYRTIKQTRKLPIN--PSRCVVDGD 1411
Query: 126 VVEQYLHLSLYDKTDLARRLGVGRYHIIDDLMQLRRM 16
+V +L L +K ++A+++G I DLM++ +
Sbjct: 1412 LVWSFLELPANEKHEVAKKIGTRIEEICADLMEIEHV 1448
>gi|24653655|ref|NP_725397.1| CG10110-PB [Drosophila melanogaster]
gi|15292103|gb|AAK93320.1| LD38533p [Drosophila melanogaster]
gi|21627189|gb|AAM68553.1| CG10110-PB [Drosophila melanogaster]
Length = 1420
Score = 649 bits (1673), Expect = 0.0
Identities = 443/1533 (28%), Positives = 740/1533 (47%), Gaps = 82/1533 (5%)
Frame = -1
Query: 4365 MYGYLRETDDSTAINFSAYGKFLPGENTGFQLLTIGAKFIRIFRVNPYV----LKEPGED 4198
M+ ++T +TA+ FS +F N L+ GA ++++R+ P V ++
Sbjct: 1 MFSMCKQTHSATAVEFSIACRFF--NNLDENLVVAGANVLKVYRIAPNVEASQRQKLNPS 58
Query: 4197 NEEWQQKTKLECMFSCRLLN-----KCHSIAVARVPQLPDQDSILMTFDDAKLSIVSINE 4033
K +LEC+ + L +C S+A A +D++L++F DAKLS++ +
Sbjct: 59 EMRLAPKMRLECLATYTLYGNVMSLQCVSLAGAM------RDALLISFKDAKLSVLQHDP 112
Query: 4032 KERNMQTISLHAFENEYLRDGFINHFQPPLVRSDPSNRCAACLVYGKHIAILPFHENSKR 3853
++T+SLH FE + +R G+ + P VR DP +RCA LVYGK + +LPF +++
Sbjct: 113 DTFALKTLSLHYFEEDDIRGGWTGRYFVPTVRVDPDSRCAVMLVYGKRLVVLPFRKDNSL 172
Query: 3852 ------------------------IHSYVIPLKQIDPRLDNIADMVFLDGYYEPTILFLY 3745
+ SY+I L+ +D ++DN+ D+ FL GYYEPT+L LY
Sbjct: 173 DEIELADVKPIKKAPTAMVSRTPIMASYLIALRDLDEKIDNVLDIQFLHGYYEPTLLILY 232
Query: 3744 EPIQTTPGRACVRYDTMCIMGVSVNIVDRQFAVVWQTANLPMDCSQLLPIPKPLGGALVF 3565
EP++T PGR ++ PI KP+GG LV
Sbjct: 233 EPVRTCPGRI-----------------------------------KVYPIQKPIGGCLVM 257
Query: 3564 GSNTVVYLNQAVPPCGLVLNSCYDGFTKFPLKDLKHLKMTLDCSTSVYMEDGRIAVGSRD 3385
N V+YLNQ+VPP G+ LNS D T FPLK ++++LDC+ +++ ++ + R
Sbjct: 258 TVNAVIYLNQSVPPYGVSLNSSADNSTAFPLKPQDGVRISLDCANFAFIDVDKLVISLRT 317
Query: 3384 GDLFLLRLMTSSGGGTVKSLEFSKVYETSIAYSLTVCAPGHLFVGSRLGDSQLLEY---- 3217
GDL++L L S TV++ F K + + + V ++F+GSRLG+S LL +
Sbjct: 318 GDLYVLTLCVDS-MRTVRNFHFHKAAASVLTSCICVLHSEYIFLGSRLGNSLLLHFTEED 376
Query: 3216 -----TLLKTTRDCAVKRLKIDNKDPAAAEI----------------ELDEDDMELYGGA 3100
TL + + ++ + ++D EI ++++++E+YG
Sbjct: 377 QSTVITLDEVEQQSEQQQRNLQDEDQNLEEIFDVDQLEMAPTQAKSRRIEDEELEVYGSG 436
Query: 3099 XXXXXXXXXXXXXESLQFRELDRLRNVGPVKSMCVGRPNYMSNDLVDAK-----RRDPVF 2935
F D L NV P+ MC G D V + +D
Sbjct: 437 -----AKASVLQLRKFIFEVCDSLMNVAPINYMCAGERVEFEEDGVTLRPHAESLQDLKI 491
Query: 2934 DLVTASGHGKNGALCVHQRSLRPEIITSSLLEGAEQLWAV------GRKENESHKYLIVS 2773
+LV A+GH KNGAL V + P+IITS L+G +W V N+ H ++++S
Sbjct: 492 ELVAATGHSKNGALSVFVNCINPQIITSFELDGCLDVWTVFDDATKKSSRNDQHDFMLLS 551
Query: 2772 RVRSTXXXXXXXXXXXXXXXLFVTGEPTVAAGELSQGALAVQVTSTCIALVTDGQQMQEV 2593
+ ST F +PT+ G L Q VQVT+ + L+ + +Q V
Sbjct: 552 QRNSTLVLQTGQEINEIENTGFTVNQPTIFVGNLGQQRFIVQVTTRHVRLLQGTRLIQNV 611
Query: 2592 HIDSNFPVIQASIVDPYVALLTQNGRLLLYELVMEPYVQLREVDISATSFATWHATAQNL 2413
ID PV+Q SI DPYV L NG+++ + LRE + H T +
Sbjct: 612 PIDVGSPVVQVSIADPYVCLRVLNGQVIT--------LALRETRGTPRLAINKH-TISSS 662
Query: 2412 TQLTSISIYADASEIMKFAAAEKSMXXXXXXXGEVSTAENAMMKKEQHEEAILLHGEDDD 2233
+ +IS Y D S + F + + MK E + + +++D
Sbjct: 663 PAVVAISAYKDLSGL--FTVKGDDINLTGSSNSAFGHSFGGYMKAEPNMKV----EDEED 716
Query: 2232 FLYGDEDETIMEQNFPVENGEATIKQSNTRKRKRLGHDAIQSSRGGEQSDAIDPTRTFSS 2053
LYGD F + + KQS + +Q+
Sbjct: 717 LLYGDAGSA-----FKMNSMADLAKQSKQKNSDWWRRLLVQAKP---------------- 755
Query: 2052 ISHWLIVSHENGRLSIHSLPEMEVVYQIGRFSNVPELLVDLTVXXXXXXXXXXXXXXXXX 1873
S+WL+V+ ++G L I+S+P+M++VY + N +L D
Sbjct: 756 -SYWLVVARQSGTLEIYSMPDMKLVYLVNDVGNGSMVLTD------------------AM 796
Query: 1872 ASVPTDEAEQLNTE--MKQLC-------ERVLEAQIVGMGINQAHPILMAIVDEQVVLYE 1720
VP Q N++ + Q C LE ++G+G+N P+L+ ++++Y+
Sbjct: 797 EFVPISLTTQENSKAGIVQACMPQHANSPLPLELSVIGLGLNGERPLLLVRTRVELLIYQ 856
Query: 1719 MFSSSNPIPGHLGISFRKLPHFICL---RTSSHLNSDGKRAPFEMKINNGKRFSLIHPFE 1549
+F GHL I FRK+ L T L+ + ++ E K + PF
Sbjct: 857 VFRYPK---GHLKIRFRKMDQLNLLDQQPTHIDLDENDEQEEIESYQMQPKYVQKLRPFA 913
Query: 1548 RVSSVNNGVMIVGAVPTLLVYGAWGGMQTHQMTVDGPIKAFTPFNNENVLHGIVYMTQHK 1369
V + +GVM+ G P + G ++ H++ +G +++F FNN N+ +G +Y
Sbjct: 914 NVGGL-SGVMVCGVNPCFVFLTFRGELRIHRLLGNGDVRSFAAFNNVNIPNGFLYF-DTT 971
Query: 1368 SELRIARMHPDFDYEMPYPVKKIEVGRTIHHVRYLMNSDVYAVVSSIPKPSNKIWVVMND 1189
EL+I+ + Y+ +PV+K+ + T + Y + VY +++ +P K + +
Sbjct: 972 YELKISVLPSYLSYDSVWPVRKVPLRCTPRQLVYHRENRVYCLITQTEEPMTKYYRFNGE 1031
Query: 1188 DKQEEIHEKDENFVLPAPPKYTLNLFSSQDWAAVPNTEISFEDMEAVTACEDVALKSEST 1009
DK+ + E F+ P ++ + L S + W VP+ I+FE E VTA + V L E T
Sbjct: 1032 DKELSEESRGERFIYPIGSQFEMVLISPETWEIVPDASITFEPWEHVTAFKIVKLSYEGT 1091
Query: 1008 ISGLETLLAMGTVNNYGEEVLVRGRIILCEVIEVVPEPDQPTSNRKIKVLFDKEQKGPVT 829
SGL+ L +GT NY E++ RG I + ++IEVVPEP +P + KIK +F KEQKGPV+
Sbjct: 1092 RSGLKEYLCIGTNFNYSEDITSRGNIHIYDIIEVVPEPGKPMTKFKIKEIFKKEQKGPVS 1151
Query: 828 GLCAINGLLLCGMGQKVFIWQFKDNDLMGISFLDMHYYVYQLHSLRTIAIACDARESMSL 649
+ + G L+ G+GQK++IWQ +D DL+G++F+D + YV+Q+ +++++ D +S+SL
Sbjct: 1152 AISDVLGFLVTGLGQKIYIWQLRDGDLIGVAFIDTNIYVHQIITVKSLIFIADVYKSISL 1211
Query: 648 IRFQEDNKAMSIASRDDRKCAQPPMASQLVVDGAHVGFLLSDETGNITMFNYAPEAPESN 469
+RFQE+ + +S+ASRD + +VD +++GFL++D NI ++ Y PEA ES
Sbjct: 1212 LRFQEEYRTLSLASRDFNPL--EVYGIEFMVDNSNLGFLVTDAERNIIVYMYQPEARESL 1269
Query: 468 GGERLTVRAAINIGTNINAFVRLRGHTSLLQLNNEDEKEAIEQRMTTVFASLDGSFGFVR 289
GG++L +A ++G +N R++ H L ++ + E + V+ +LDG+ G+
Sbjct: 1270 GGQKLLRKADYHLGQVVNTMFRVQCHQKGL---HQRQPFLYENKHFVVYGTLDGALGYCL 1326
Query: 288 PLTEKSYRRLHFLQTFIGSVTPQIAGLHIKGSRSAKPSQPIVNGRN-ARNLIDGDVVEQY 112
PL EK YRR LQ + S + GL+ K R+ K S+ G N +R +IDGD++ Y
Sbjct: 1327 PLPEKVYRRFLMLQNVLLSYQEHLCGLNPKEYRTLKSSKK--QGINPSRCIIDGDLIWSY 1384
Query: 111 LHLSLYDKTDLARRLGVGRYHIIDDLMQLRRMA 13
++ ++ ++A+++G I+ DL+++ R+A
Sbjct: 1385 RLMANSERNEVAKKIGTRTEEILGDLLEIERLA 1417