Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm1/seq/B0457.1
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: B0457.1 CE02945 locus:lat-1 G-protein coupled receptor protein status:Partially_confirmed TR:Q17505 protein_id:CAA91091.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
7tm_2 7 transmembrane receptor (Secretin family) 346.0 9.5e-103 1
Gal_Lectin Galactose binding lectin domain 156.9 3.5e-43 1
GPS Latrophilin/CL-1-like GPS domain 88.5 3.7e-23 1
HRM Hormone receptor domain 57.1 6.5e-14 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
Gal_Lectin 1/1 51 133 .. 1 93 [] 156.9 3.5e-43
HRM 1/1 181 240 .. 1 79 [] 57.1 6.5e-14
GPS 1/1 493 541 .. 1 54 [] 88.5 3.7e-23
7tm_2 1/1 548 799 .. 1 273 [] 346.0 9.5e-103
Alignments of top-scoring domains:
Gal_Lectin: domain 1 of 1, from 51 to 133: score 156.9, E = 3.5e-43
*->LsCpgGqkiisIkfAsyGRvvtpdgvCgsd.gaqfsngsChpaskSy
LsCp+ +k+isI+ ++yGR ++++vC +d+++++sn++C+ ++k++
B0457.1 51 LSCPA-GKVISIVLGNYGR--FSVAVCLPDnDIVPSNINCQ-NHKTK 93
sivekdrisekCvGkssCtVvVsssvFgskgDPCpgtlKyLaVeyiC<-*
si+ek kC+G+s+C+++V++++F+ +DPCp+t+KyL+V+y+C
B0457.1 94 SILEK-----KCNGDSMCYFTVDKKTFT--EDPCPNTPKYLEVKYNC 133
HRM: domain 1 of 1, from 181 to 240: score 57.1, E = 6.5e-14
*->glyCpatwDgilCWPrTpaGtlvvvpCPdyfsGfnydttgedfsngn
+ +C+at +++ W+ T+ Gt+ + pCP++ sG
B0457.1 181 DVFCSATNRRGVNWQNTKSGTTSSAPCPEGSSGK------------- 214
asRnCtenGwwerhpnsnwpwpdytnCtspey<-*
+ Cte+G+w + + p+ ++C+s++
B0457.1 215 QLWACTEEGQWLT------EFPNSAGCESNWI 240
GPS: domain 1 of 1, from 493 to 541: score 88.5, E = 3.7e-23
*->snpiCvfWdeselslgvWstdrGCelvetskpshttCsCnHLTsFAv
snp+Cv+W+++e +W++ +GC+l++++k ++t+C+C+HLT+FAv
B0457.1 493 SNPTCVWWNHHE---LKWKP-SGCKLSYHNK-TMTSCDCTHLTHFAV 534
Lmdvspn<-*
Lmdv+++
B0457.1 535 LMDVRGH 541
7tm_2: domain 1 of 1, from 548 to 799: score 346.0, E = 9.5e-103
*->allLkviytVGyslSsLvcLllaiaifllfRkLrctRnyIHmNLfls
+lL+++++VG+++S ++cLll+++ +l+f + +R++IH NL+ls
B0457.1 548 QTLLTLLTYVGCIIS-IICLLLTFFAYLIFSRNGGDRVFIHENLCLS 593
fiLralsfLigdavllnsg.CkvvavflhYfflaNFfWmLvEGlYLytLl
+ +++++fL+g++++++s +C ++av l+Y+fl++ +WmL+EG++ +++l
B0457.1 594 LAIAEITFLAGITRTEDSLqCGIIAVALMYMFLSALTWMLLEGYHIHRML 643
vvtvevffserkrlwwYlliGWGvPavfvtiwaivrpdkygpilaegpag
+evf+s++ r++ Yll+G+ Pa+++ +++++ +d g
B0457.1 644 ---TEVFPSDP-RRFTYLLVGYIPPAIITLVAYLYNSD-----------G 678
ygnegcCWlsndtnsgfwWiikGPilliilvNfiffinilriLvqKlri.
+g++++CWls+ +++f+W ++GP+++i+++N ++++ +l++++q+++++
B0457.1 679 FGTPDHCWLST--QNNFIWFFAGPACFIFCANSLVLVKTLCTVYQHTSGg 726
d.slspqtgetdqyrkkrlvkstLlLlPLLGvtwilflfapedqsqGtls
+ ++++++ +++r ++vk++L+L LLGvtwi++lf++ed +s
B0457.1 727 YlPCRHDVDSGRSIR--NWVKGSLALASLLGVTWIFGLFWVEDS----RS 770
lvflylfliLnSfQGffVavlYCflNgEV<-*
+v++y+f+i nS+QG+f++++++++ +++
B0457.1 771 IVMAYVFTISNSLQGLFIFLFHVVFAEKM 799