Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/B0464.5b
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Query:  B0464.5b  CE20457  locus:spk-1 Eukaryotic protein kinase domain status:Confirmed TR:Q9XVY0 protein_id:CAA79541.1

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
pkinase  Protein kinase domain                          156.5    4.5e-43   2
ARS2     Arsenite-resistance protein 2                    1.7          9   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
ARS2       1/1     257   265 ..     1     9 [.     1.7        9
pkinase    1/2     134   284 ..     1   142 [.   101.9  3.7e-27
pkinase    2/2     453   616 ..   137   294 .]    55.7  2.4e-14

Alignments of top-scoring domains:
ARS2: domain 1 of 1, from 257 to 265: score 1.7, E = 9
                   *->MPNRCGIIH<-*
                      M   CGIIH
    B0464.5b   257    MHEKCGIIH    265

pkinase: domain 1 of 2, from 134 to 284: score 101.9, E = 3.7e-27
                   *->yelleklGeGsfGkVykakhkdktgkiVAvKilkkekesikekrflr
                      y++++klG G+f++V++a++   +++ VA+Ki+k  ++++++  +l
    B0464.5b   134    YHVIRKLGWGHFSTVWLAWDT-QDKRFVAMKIVKSAEHYTEA--ALD 177

                   EiqilkrLs........HpNIvrligvfed...tddhlylvmEymegGdL
                   Ei++l ++++ ++++ +   +v+l++ f+ ++  ++h+ +v+E +++  L
    B0464.5b   178 EIKLLLSVRsadpndigCHKVVQLLDEFTVtgiNGQHVAMVFEVLGCNLL 227

                   fdylrrnggplsekeakkialQilrGleYLHsng.ivHRDLKpeNILlde
                   + ++r+n + l  ++++ki++Q+l++l Y+H++ +i+H D+KpeN+L++
    B0464.5b   228 KLIIRSNYRGLHLEQVRKICRQVLEALGYMHEKCgIIHTDIKPENVLITM 277

                   ndgtvKi<-*
                    +  +Ki
    B0464.5b   278 SREEIKI    284

pkinase: domain 2 of 2, from 453 to 616: score 55.7, E = 2.4e-14
                   *->dgtvKiaDFGLArllesssklttfvGTpwYmmAPEvilegrgysskv
                      d +vKiaD G A+ +  ++++t+   T+ Y+ A Ev l g+gy++++
    B0464.5b   453    DIDVKIADLGNACWV--NHHYTDDIQTRQYR-ALEV-LIGSGYGPPA 495

                   DvWSlGviLyElltggplfpgadl.paftg.gd.evdqli.if.vlklPf
                   D+WS  ++ +El+tg ++++ +  ++  + ++d+++  +i+++ +  +P
    B0464.5b   496 DIWSTACMAFELATG-DYLFEPHQgD--NYsRDeDHLAHIsELlGAIPPS 542

                   sdelpktridpleelfriikrp........glrlplpsncSee....lkd
                     + + ++++ +++   ++++ ++ ++ +  + l++ +++S e+ +++ +
    B0464.5b   543 I-YKKGKHWREFFHKNGHLLHIhqlkpwslYEVLRQKYEWSHEdaqqFES 591

                   LlkkcLnkDPskRpGsatakeilnhpwf<-*
                   +l+ +L++D +kR    tak +l+hp++
    B0464.5b   592 FLRPMLDFDQEKRS---TAKIALKHPFL    616



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