Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm1/seq/B0491.8b
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Query: B0491.8b CE27790 locus:clh-2 chloride channel protein status:Confirmed TR:Q95NL9 protein_id:CAC42266.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
voltage_CLC Voltage gated chloride channel 642.3 2.7e-189 1
CBS CBS domain 36.3 3.3e-08 2
DAO FAD dependent oxidoreductase 6.2 0.98 1
DS Deoxyhypusine synthase 1.5 8.8 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
DS 1/1 528 538 .. 327 337 .] 1.5 8.8
voltage_CLC 1/1 134 546 .. 1 455 [] 642.3 2.7e-189
DAO 1/1 585 602 .. 380 397 .] 6.2 0.98
CBS 1/2 579 635 .. 1 54 [] 18.6 0.0023
CBS 2/2 772 810 .. 15 54 .] 17.8 0.004
Alignments of top-scoring domains:
DS: domain 1 of 1, from 528 to 538: score 1.5, E = 8.8
*->afPlLvaglla<-*
++P+L+a+l++
B0491.8b 528 ILPVLIAMLMG 538
voltage_CLC: domain 1 of 1, from 134 to 546: score 642.3, E = 2.7e-189
*->fslvlvllaalLvkkfaPaAaGSGIPEiKtiLnGikivdgkgylrlr
++++l+++aa+++++++++A+GSGIPE+K+i++G+k+ ++yl+ r
B0491.8b 134 HIVILTMFAAIFCQIVSKQAVGSGIPEVKVIMHGFKM---ENYLTTR 177
tllvKvvGlalsigsGLslGKEGPfVHiGaciaalLskggStslrlqfsl
tl++K+vGl+l++g+GL+ GKEGPfVH+Ga++a+lLsk++S++ q+s+
B0491.8b 178 TLVAKMVGLTLAMGGGLPIGKEGPFVHMGAIVATLLSKITSAC---QYSA 224
fkyseedrRkdrRdLlaaGaAaGvAaAFgAPiGGVLFslEevssenarfn
f+ +e + +++l+ G+A+G+A++F+APiG+VL+++E++s+ +f+
B0491.8b 225 FFSNEGRE----MEMLSSGCAVGIACTFSAPIGAVLYAIESTSK---YFA 267
vkllwrsLFFasavaafvlrlinsffvsgkcgdFgtglalFdvsfrtdrf
vk++wr+ F+a++++a+v+r++n ffv++++++ t++a ++++f+td
B0491.8b 268 VKNYWRG-FLAATCSAIVFRCAN-FFVTAEQSG--TITAFYQTRFPTD-- 311
pwtlfElplFillGifgGllGalFnrlnrkilkfrkKnrylskklkkppv
++ ++Elp+F+llG+++Gl+G++F++ +r+i+ fr Knr++++++ +++
B0491.8b 312 CFLVEELPIFLLLGFISGLMGSFFIFIHRQISIFRSKNRVYKLIFRNNFL 361
levalvglltavlsfplplllgcagglelveegrtlnilfdnCtwgeynd
++ +++++++vl+fp++l++++ag+l+++e t++++f+nCtw++
B0491.8b 362 AFTVFMAFVVGVLTFPNGLGRYFAGRLTFRE---TMADFFNNCTWVS--- 405
lasllcntpedavlslFhwnipgegdffaftlLlllliakflltlltfGi
+++++++++ + hw++++egd+++ft+L+l++i++f+l++++++i
B0491.8b 406 ----NDSRRCPDTILT-HWTGGSEGDVSIFTSLVLYYILYFVLVAICISI 450
gvPgGlFvPslaiGAalGrlvGiaverlimavlsHdwfpfgifcegfpdc
vP+G+FvPs++iGAa Grl+G ++m+vl fp+g+++ g ++
B0491.8b 451 NVPAGVFVPSFIIGAAGGRLMG-----ETMVVL----FPEGMRGPG-GPP 490
ilePGlYAvlGAAAflGGvvrmTvslaVImfElTGnlsvilPlmvAvlia
i+ PGlYAv+GAAA++G +v++T+s+ VI++ElTG+ls ilP+++A+l+
B0491.8b 491 IH-PGLYAVVGAAAYTG-AVTHTLSVSVIICELTGQLSPILPVLIAMLMG 538
klvadslg<-*
++v+ +l+
B0491.8b 539 NAVCKFLQ 546
DAO: domain 1 of 1, from 585 to 602: score 6.2, E = 0.98
*->liwGgaltayrlvaedlv<-*
+i+++++++yr ++e+l+
B0491.8b 585 VIYITKDMTYREMKEILQ 602
CBS: domain 1 of 2, from 579 to 635: score 18.6, E = 0.0023
*->dimtrdvvtvspdttleealelmren.gisrlPVvded..gklvGiv
+ m +dv++++ d+t +e e+++ ++++++P+v ++++ l+G v
B0491.8b 579 QLMVTDVIYITKDMTYREMKEILQLApHLRSFPIVTDHenKILLGSV 625
tlrDllralv<-*
+r l l+
B0491.8b 626 AKRYLTMLLR 635
CBS: domain 2 of 2, from 772 to 810: score 17.8, E = 0.004
*->tleealelmrengisrlPVvdedgklvGivtlrDllralv<-*
+l+++ l++ g+s++ V+d gklvG+v l++l++a++
B0491.8b 772 SLYKVHTLFSLLGLSHAYVTDC-GKLVGVVGLKELRDAMA 810