Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm1/seq/C05B5.5
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Query: C05B5.5 CE00051 EGF repeats status:Partially_confirmed SW:P34293 protein_id:CAA83593.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
EB EB module 106.4 5.5e-28 2
F-box F-box domain 21.0 0.00077 1
dickkopf_N Dickkopf N-terminal cysteine-rich region 8.8 0.15 3
granulin Granulin 4.3 5.7 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
F-box 1/1 13 60 .. 1 46 [] 21.0 0.00077
dickkopf_N 1/3 363 382 .. 35 54 .] 0.9 64
granulin 1/1 396 409 .. 28 43 .] 4.3 5.7
EB 1/2 369 436 .. 1 63 [] 54.1 7e-13
dickkopf_N 2/3 419 438 .. 35 54 .] 14.2 0.0025
EB 2/2 513 577 .. 1 63 [] 60.3 1.5e-14
dickkopf_N 3/3 523 579 .. 1 54 [] 7.6 0.39
Alignments of top-scoring domains:
F-box: domain 1 of 1, from 13 to 60: score 21.0, E = 0.00077
*->fslldLPdellleIlsrLdpkdllrlslVSkrwrslvdsl.lwf.kl
+ dLPd + ++I+++L+p ++++ls+ Sk + + + +++ k
C05B5.5 13 LNYVDLPDTVHRKIFEYLNPWEIFKLSRISKAIHVTILKNkKFAvKD 59
l<-*
+
C05B5.5 60 I 60
dickkopf_N: domain 1 of 3, from 363 to 382: score 0.9, E = 64
*->CtRDamCCpgnlCvNGiCtp<-*
C++ a C p+ Cv G+C
C05B5.5 363 CSTNADCLPSGNCVDGECLV 382
granulin: domain 1 of 1, from 396 to 409: score 4.3, E = 5.7
*->CPqGfhCdadggrClq<-*
CP G+ C + +C +
C05B5.5 396 CPNGYQCVNR--KCSR 409
EB: domain 1 of 2, from 369 to 436: score 54.1, E = 7e-13
*->ClsgqVlingqCvakelnkvnpGesgCeaseQCqggwpgSvCingmC
Cl+ +++g+C l+ ++ G+ C+++ QC++g ++C n++C
C05B5.5 369 CLPSGNCVDGEC----LVDNGNGG-LCTTNTQCPNG---YQCVNRKC 407
................eCpegvpkttrvngvC<-*
++++++ ++ + +++eCp+g t++ ngvC
C05B5.5 408 srnsrhfndlpcvtetECPPG---TRCINGVC 436
dickkopf_N: domain 2 of 3, from 419 to 438: score 14.2, E = 0.0025
*->CtRDamCCpgnlCvNGiCtp<-*
C + +C pg++C NG+Ct
C05B5.5 419 CVTETECPPGTRCINGVCTG 438
EB: domain 2 of 2, from 513 to 577: score 60.3, E = 1.5e-14
*->ClsgqVlingqCvakelnkvnpGesgCeaseQCqggwpgSvCingmC
C + ++++g+C l+ +++G+ C++s QC+ g ++Ci+g+C
C05B5.5 513 CGNKGICVDGEC----LVDNGLGG-YCSTSTQCPTG---YQCIDGKC 551
.............eCpegvpkttrvngvC<-*
+++++ ++ eCp+g t++ ngvC
C05B5.5 552 ktkrhflappcvaECPPG---TRCINGVC 577
dickkopf_N: domain 3 of 3, from 523 to 579: score 7.6, E = 0.39
*->eCisDeDCgtdeYChssrqgks..lvCl..pCRkrrkr....CtRDa
eC+ D g++ YC+ s+q ++++ C ++ C+++r ++C a
C05B5.5 523 ECLVDN--GLGGYCSTSTQ-CPtgYQCIdgKCKTKRHFlappCV--A 564
mCCpgnlCvNGiCtp<-*
+C pg++C NG+Ct
C05B5.5 565 ECPPGTRCINGVCTG 579