Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm1/seq/C10C6.1
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Query: C10C6.1 CE20493 locus:kin-4 serine\/threonine kinase status:Partially_confirmed TR:P90744 protein_id:CAB05684.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
pkinase Protein kinase domain 262.8 4.5e-75 1
PDZ PDZ domain (Also known as DHR or GLGF) 31.5 1.7e-07 1
Col_cuticle_N Nematode cuticle collagen N-terminal d 4.0 9.3 1
Xlink Extracellular link domain 2.4 1.8 1
Acetate_kinase Acetokinase family 1.2 9.1 1
Ca_channel_B Dihydropyridine sensitive L-type calci 1.0 5.1 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
Col_cuticle_N 1/1 32 54 .. 43 66 .] 4.0 9.3
Xlink 1/1 370 381 .. 1 12 [. 2.4 1.8
pkinase 1/1 358 633 .. 1 294 [] 262.8 4.5e-75
Acetate_kinase 1/1 705 727 .. 248 270 .. 1.2 9.1
PDZ 1/1 974 1041 .. 1 62 [. 31.5 1.7e-07
Ca_channel_B 1/1 1269 1312 .. 184 226 .] 1.0 5.1
Alignments of top-scoring domains:
Col_cuticle_N: domain 1 of 1, from 32 to 54: score 4.0, E = 9.3
*->eMvdvqrnvrppskpasarfgrpf<-*
eM+d +r ++p++++ s+rf+++
C10C6.1 32 EMLDQTRISGPVRQN-SSRFDSND 54
Xlink: domain 1 of 1, from 370 to 381: score 2.4, E = 1.8
*->GeVFhyrapsgR<-*
G V+++r++++R
C10C6.1 370 GAVYLVRHRETR 381
pkinase: domain 1 of 1, from 358 to 633: score 262.8, E = 4.5e-75
*->yelleklGeGsfGkVykakhkdktgkiVAvKilkkekesikek....
+ +++ + G++G Vy+++h+ +t +++A+K+++ k+++ +++ +
C10C6.1 358 FDTIRLVSNGAYGAVYLVRHR-ETRQRFALKKMN--KQTLMLRnqvd 401
rflrEiqilkrLsHpNIvrligvfedtddhlylvmEymegGdLfdylrrn
++++E il + + p++v ++g+fe t ++l++ mEy+egGd + +l++
C10C6.1 402 QVFAERDILTMADNPFVVSFYGSFE-TRQYLCMLMEYVEGGDCAALLKSA 450
ggplsekeakkialQilrGleYLHsngivHRDLKpeNILldendgtvKia
g l+ + ++ ++ ++ ++eYLHs givHRDLKp+N+L++ g++K++
C10C6.1 451 G-TLPVELVRLYVAETILAIEYLHSYGIVHRDLKPDNLLITAM-GHIKLT 498
DFGLArlle.................sssklttfvGTpwYmmAPEvileg
DFGL++ ++++ ++ + ++ + ++++GTp+Y+ APEv +++
C10C6.1 499 DFGLSKIGLmnrttlvaegydavvetQQFQDKQLCGTPEYI-APEV-ILR 546
rgysskvDvWSlGviLyElltggplfpgadlpaftggdevdqliifvlkl
rgy+++vD+W+lG+iLyE l g
C10C6.1 547 RGYGKPVDWWALGIILYEFLVG--------------------------IV 570
Pfsdelpktridpleelfriikrp.glrlplpsncSeelkdLlkkcLnkD
Pf + ++ e+lf+ + + + ++ ++ +++e+ dL +++L+k+
C10C6.1 571 PFFG-------ETPEALFSKVISEdVEYPEEDEALPPEAADLCRRLLEKN 613
PskRpG.satakeilnhpwf<-*
P++R+G+ a ++++h +f
C10C6.1 614 PAERLGtLNGAAQLMAHEFF 633
Acetate_kinase: domain 1 of 1, from 705 to 727: score 1.2, E = 9.1
*->dIDPaivvyLaeteglSadEivn<-*
+IDPa +++L +t++ a Ei++
C10C6.1 705 SIDPAHLPHLLSTANAAAKEIER 727
PDZ: domain 1 of 1, from 974 to 1041: score 31.5, E = 1.7e-07
*->evtlekevkrgglGfsikggsdk..........givvsevlpGsgaA
++t+ k ++ g+Gf++k++ +++++ + + +v+ v++G ++A
C10C6.1 974 TITIRK--GPFGFGFTLKSVRVYlgehseyytiEHIVTAVVEG-SPA 1017
eagGrLkeGDvIlsvNGqdvenmsh<-*
++ L++ D+I+ vNG +v n++h
C10C6.1 1018 FHAN-LQAEDMITHVNGHPVHNLTH 1041
Ca_channel_B: domain 1 of 1, from 1269 to 1312: score 1.0, E = 5.1
*->ywkathpPvaspss.nplelrgpatalsplqptlnqelqgsrge<-*
+ ++ h P++s ++p + ++pat++sp + + q+l +sr +
C10C6.1 1269 PSHLHHRPASSSYTtRPDGVVTPATSSSPNNSGFVQDLISSRQS 1312