Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm1/seq/C14B9.2
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Query: C14B9.2 CE30601 erp72 status:Confirmed SW:P34329 protein_id:AAM22024.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
thiored Thioredoxin 530.4 1.1e-158 3
Calsequestrin Calsequestrin 8.6 0.044 1
DSBA DSBA-like thioredoxin domain 8.1 0.57 1
NTR NTR/C345C module 4.7 6.5 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
thiored 1/3 35 139 .. 1 116 [] 179.3 9.1e-53
DSBA 1/1 167 202 .. 1 36 [. 8.1 0.57
thiored 2/3 146 254 .. 1 116 [] 186.9 4.6e-55
Calsequestrin 1/1 187 297 .. 87 196 .. 8.6 0.044
NTR 1/1 401 416 .. 112 131 .] 4.7 6.5
thiored 3/3 498 609 .. 1 116 [] 175.3 1.5e-51
Alignments of top-scoring domains:
thiored: domain 1 of 3, from 35 to 139: score 179.3, E = 9.1e-53
*->ssvvvvltdenFdeevlkaksdkpVLVdFyApWCGpCKmlAPeyekl
+++vvvltd+nFd+ ++k++ VLV+FyApWCG+CK+lAPeyek+
C14B9.2 35 DEGVVVLTDKNFDA---FLKKNPSVLVKFYAPWCGHCKHLAPEYEKA 78
AqeykgesddvkfaKVDaDenpkdlAskygVrgfPTlkffknGkkepvdy
+++++ +++aKVDa+ ++ +l ++++++g+PTlkf+k+Gk +p dy
C14B9.2 79 SSKVS-----IPLAKVDATVET-ELGKRFEIQGYPTLKFWKDGK-GPNDY 121
vgGArtkddLvafikkhlg<-*
+gG r+++++v++++++++
C14B9.2 122 DGG-RDEAGIVEWVESRVD 139
DSBA: domain 1 of 1, from 167 to 202: score 8.1, E = 0.57
*->tvdeFFDfiCPyCylakerleklvaqykdlpdgvkv<-*
+++eF+ C++C+ + +ek++++ k++ +vk+
C14B9.2 167 VLVEFYAPWCGHCKKLAPEYEKAAQKLKAQGSKVKL 202
thiored: domain 2 of 3, from 146 to 254: score 186.9, E = 4.6e-55
*->ssvvvvltdenFdeevlkaksdkpVLVdFyApWCGpCKmlAPeyekl
++vv+lt enFd+ ++ ++++VLV+FyApWCG+CK+lAPeyek+
C14B9.2 146 PEEVVTLTTENFDD---FISNNELVLVEFYAPWCGHCKKLAPEYEKA 189
AqeykgesddvkfaKVDaDenpkdlAskygVrgfPTlkffknGkkepvdy
Aq++k+++++vk+ KVDa+ ++ dl kygV+g+PT+k+++nG + dy
C14B9.2 190 AQKLKAQGSKVKLGKVDATIEK-DLGTKYGVSGYPTMKIIRNGRR--FDY 236
vgGArtkddLvafikkhlg<-*
+g+ r+++++++++++++
C14B9.2 237 NGP-REAAGIIKYMTDQSK 254
Calsequestrin: domain 1 of 1, from 187 to 297: score 8.6, E = 0.044
*->ELaAqvLEdKg..vGFglvDsekdAavAKKLGldEedslYvlKgDev
E aAq L +g++v g vD+ + + K G+ + ++++ +
C14B9.2 187 EKAAQKLKAQGskVKLGKVDATIEKDLGTKYGVSGYPTMKIIRNGRR 233
iEyDGEFsADtlvEFLLDvlEDPvEliegkrElqAFEnieDeiKLiGyFK
+y G A ++ ++ D + ++++ F D++ +iG+F
C14B9.2 234 FDYNGPREAAGIIKYMTDQSKPAAKKLPKLKDVERFMS-KDDVTIIGFFA 282
sedsEhYKAfEdAAE<-*
eds + Af d AE
C14B9.2 283 TEDSTAFEAFSDSAE 297
NTR: domain 1 of 1, from 401 to 416: score 4.7, E = 6.5
*->EeWPdewgkreecqqkrark<-*
E+W+++ + +++++++k
C14B9.2 401 EYWRSK----VLNIAQKYQK 416
thiored: domain 3 of 3, from 498 to 609: score 175.3, E = 1.5e-51
*->ssvvvvltdenFdeevlkaksdkpVLVdFyApWCGpCKmlAPeyekl
+++v++++++nFd+ v++ ++k+VL++FyApWCG+CK ++ +y +l
C14B9.2 498 KGPVKTVVGSNFDKIVND--ESKDVLIEFYAPWCGHCKSFESKYVEL 542
AqeykgesddvkfaKVDaDenpkdlAskygVrgfPTlkffknGkk.epvd
Aq++k++ ++v++aK+Da+ n+ + s++ V+gfPT++f ++Gkk+ep++
C14B9.2 543 AQALKKTQPNVVLAKMDATIND-AP-SQFAVEGFPTIYFAPAGKKsEPIK 590
yvgGArtkddLvafikkhlg<-*
y g r+++dL++f++kh+
C14B9.2 591 YSGN-RDLEDLKKFMTKHGV 609