Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/C18H2.1
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query:  C18H2.1  CE29670    status:Partially_confirmed TR:Q18102 protein_id:AAA50664.2

Scores for sequence family classification (score includes all domains):
Model         Description                               Score    E-value  N
--------      -----------                               -----    ------- ---
WSN           Domain of unknown function                189.8    4.4e-53   2
ank           Ankyrin repeat                             39.9    1.4e-09   1
BRCT          BRCA1 C Terminus (BRCT) domain             19.2    0.00014   2
DUF278        DUF278                                     15.7     0.0054   1
synaptobrevin Synaptobrevin                               5.3        5.9   2
MtN3_slv      MtN3/saliva family                          4.7        7.6   1
Baculo_E56    Baculoviral E56 protein, specific to OD     3.9        3.3   1
LacD          Tagatose 1,6-diphosphate aldolase, (Lac     3.3        3.7   1
Fragilysin    Fragilysin metallopeptidase (M10C) ente     2.6          6   1

Parsed for domains:
Model         Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------      ------- ----- -----    ----- -----      -----  -------
WSN             1/2     230   298 ..     1    72 []    92.4  2.1e-24
LacD            1/1     499   522 ..   309   332 .]     3.3      3.7
synaptobrevin   1/2     963   981 ..    71    89 .]    -6.4    1e+04
Baculo_E56      1/1     966   990 ..   297   321 .]     3.9      3.3
ank             1/1    1053  1085 ..     1    33 []    39.9  1.4e-09
BRCT            1/2    1168  1223 ..    49    99 .]    16.4    0.001
BRCT            2/2    1248  1287 ..     1    49 [.     2.9       14
WSN             2/2    1385  1453 ..     1    72 []   101.0    8e-27
synaptobrevin   2/2    1447  1472 ..    33    58 ..     1.5       66
DUF278          1/1    1487  1523 ..   148   184 ..    15.7   0.0054
Fragilysin      1/1    1555  1564 ..   373   382 .]     2.6        6
MtN3_slv        1/1    1729  1744 ..    74    89 .]     4.7      7.6

Alignments of top-scoring domains:
WSN: domain 1 of 2, from 230 to 298: score 92.4, E = 2.1e-24
                   *->skLqtvienlsilaRVtNAIsLqaglingsiksddvIaELLniGtin
                       +L +++++l+i+ RVtNAI Lqa+ i++ +k++dv+aEL++   ++
     C18H2.1   230    PALVLAYNKLAIITRVTNAIVLQAEGIRKLVKVRDVVAELIR---SP 273

                   psqlselinvdlkkiveglngLkei<-*
                   ++++++l++vd+++i   ln+++e+
     C18H2.1   274 NASFYDLMDVDPTNIFPVLNEIIEA    298

LacD: domain 1 of 1, from 499 to 522: score 3.3, E = 3.7
                   *->tvgfknldeLnkVldetaspwtek<-*
                      t gf+n+ ++ kV ++  s+w +
     C18H2.1   499    TLGFPNIGDIAKVSEDLKSSWFKS    522

synaptobrevin: domain 1 of 2, from 963 to 981: score -6.4, E = 1e+04
                   *->ivglvvvlllliiivylcg<-*
                      ++gl+++++++++iv++++
     C18H2.1   963    AIGLCIGIFIILFIVVFVV    981

Baculo_E56: domain 1 of 1, from 966 to 990: score 3.9, E = 3.3
                   *->LviGgVlllilIgyvvFKvlnkkrg<-*
                      L iG+ + l ++++vv+++  ++r+
     C18H2.1   966    LCIGIFIILFIVVFVVYGRTPSGRQ    990

ank: domain 1 of 1, from 1053 to 1085: score 39.9, E = 1.4e-09
                   *->dGnTPLHlAakrgnlevvklLlqrGAdlnaqdd<-*
                      +GnTPLH+A+k+g++e+v+ L+++GAd  + +
     C18H2.1  1053    YGNTPLHVASKSGYPEIVEILIKNGADRTLLNA    1085

BRCT: domain 1 of 2, from 1168 to 1223: score 16.4, E = 0.001
                   *->ktthvivgenagsklekalk....aialgipivteeWlldcikegkl
                      ++th+iv+++++  l + + +  ++   g+ i++ +W++dc+ +  l
     C18H2.1  1168    SITHFIVKTDENGTLVTDAFqllsWVLSGVLIMKNSWMKDCLGNESL 1214

                   lpe.dpyll<-*
                   +  +++y +
     C18H2.1  1215 IKKdYNYFV    1223

BRCT: domain 2 of 2, from 1248 to 1287: score 2.9, E = 14
                   *->eklfsgltfvltgtknaaviieamldseer.elkelieklGGkvt.s
                      + +++g+  v+ +            d ++ + + +++ ++GG+ ++
     C18H2.1  1248    MLFLHGVYAVVVS-----------IDCSNIgAITAIVTNNGGVMCeK 1283

                   lskk<-*
                   + +k
     C18H2.1  1284 FPEK    1287

WSN: domain 2 of 2, from 1385 to 1453: score 101.0, E = 8e-27
                   *->skLqtvienlsilaRVtNAIsLqaglingsiksddvIaELLniGtin
                      s L++v + l ++aRVtNAIsL+ag+i++++k+ dv++E L    i+
     C18H2.1  1385    SSLEKVRDVLTMVARVTNAISLEAGAIRKTLKLTDVVSEVLD---ID 1428

                   psqlselinvdlkkiveglngLkei<-*
                   p++l+el+n+d+++++++l++++++
     C18H2.1  1429 PGKLDELLNLDSAGLNAHLEKMIHR    1453

synaptobrevin: domain 2 of 2, from 1447 to 1472: score 1.5, E = 66
                   *->LdeLvDktdnLqassdqFrksakklr<-*
                      L+++ ++ ++L +  +qF+++++kl+
     C18H2.1  1447    LEKMIHRYQKLTQDTEQFKDKLTKLK    1472

DUF278: domain 1 of 1, from 1487 to 1523: score 15.7, E = 0.0054
                   *->ikkMDRaatEaeLwkWEfYphFrYYRetLGqFEAklR<-*
                      +kk+    t+ eL kWE+Yp++ YYR  L+  E  +R
     C18H2.1  1487    DKKLNEEDTDRELTKWEYYPFIKYYRVNLADWERRKR    1523

	[output cut off at A = 10 top alignments]


[DB home][top]