Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/C28C12.10
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Query:  C28C12.10  CE27740    status:Partially_confirmed TR:Q18284 protein_id:AAB37553.2

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N
--------    -----------                                 -----    ------- ---
FYVE        FYVE zinc finger                            102.7    1.5e-27   1
PH          PH domain                                    57.2      1e-14   2
MtrG        Tetrahydromethanopterin S-methyltransfera     8.0       0.82   1
RhoGEF      RhoGEF domain                                 7.2       0.58   1
ATP-synt_DE ATP synthase, Delta/Epsilon chain, long a     4.4        8.4   1
pec_lyase_N Pectate lyase, N terminus                     2.7          5   1
Tektin      Tektin family                                 2.3        6.6   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
pec_lyase_N   1/1      74    80 ..    73    79 .]     2.7        5
MtrG          1/1     380   392 ..    36    48 ..     8.0     0.82
RhoGEF        1/1     525   548 ..   184   207 .]     7.2     0.58
ATP-synt_DE   1/1     525   550 ..    27    52 .]     4.4      8.4
Tektin        1/1     638   650 ..   381   393 .]     2.3      6.6
PH            1/2     578   673 ..     1    85 []    54.7  5.2e-14
FYVE          1/1     771   837 ..     1    72 []   102.7  1.5e-27
PH            2/2     897   998 ..     1    85 []     6.1      2.5

Alignments of top-scoring domains:
pec_lyase_N: domain 1 of 1, from 74 to 80: score 2.7, E = 5
                   *->NsTRReL<-*
                      N+TRR+L
   C28C12.10    74    NTTRRSL    80

MtrG: domain 1 of 1, from 380 to 392: score 8.0, E = 0.82
                   *->EvaQriGKkvGRD<-*
                      E+  r+GK+vGRD
   C28C12.10   380    EYMERFGKRVGRD    392

RhoGEF: domain 1 of 1, from 525 to 548: score 7.2, E = 0.58
                   *->dqpdredLkkaldllqdlaksiNe<-*
                      d++++e +++a+++l+++ + +N+
   C28C12.10   525    DCDEKEKAQEAIQKLENVTQAVNQ    548

ATP-synt_DE: domain 1 of 1, from 525 to 550: score 4.4, E = 8.4
                   *->DdkekirAeaaLkrArARlkaakflk<-*
                      D  ek++A++a+++  +  +a+++++
   C28C12.10   525    DCDEKEKAQEAIQKLENVTQAVNQKM    550

Tektin: domain 1 of 1, from 638 to 650: score 2.3, E = 6.6
                   *->rekCmqlRtslps<-*
                      r++C+q+R++ +s
   C28C12.10   638    RIRCLQIRSRVKS    650

PH: domain 1 of 2, from 578 to 673: score 54.7, E = 5.2e-14
                   *->vikeGwLlkks.kswkkRyfvLfndvLlyykdsk.....kkpkgsip
                      +i++ +++k+++k+ ++Ry+vLf+d+L++++ s++++ + +    ip
   C28C12.10   578    LIRQSEVMKQTrKELQPRYLVLFTDYLWICRVSSsgqfdINRSYRIP 624

                   Lsgcqvek.pd...kncFeirt.drtlllqaeseeerkeWvkaiqsair<
                   L+ +++e+ +++++ +c++ir++ ++ l+ ++se+er++W +++ +a++
   C28C12.10   625 LEYMKFERmEEderIRCLQIRSrVKSALIIFSSEKERNQWTDDLTKAQY  673

                   -*

   C28C12.10     -    -

FYVE: domain 1 of 1, from 771 to 837: score 102.7, E = 1.5e-27
                   *->phWvpDeevsnCmr..CgkpFtkltkRrHHCRaCGrifCgsCssktv
                      p+W+pD+ +++C +++C+++F+ +++RrHHCR+CG+++C++C  +
   C28C12.10   771    PVWLPDNISNECLMegCSTEFN-IINRRHHCRDCGWLICKFCKGQAP 816

                   llpylgiaaliekpvRVCdsCydrlnk<-*
                   l++y+      +++++VC++C+dr++k
   C28C12.10   817 LSKYD------FTKQNVCSECFDRHYK    837

PH: domain 2 of 2, from 897 to 998: score 6.1, E = 2.5
                   *->vikeGwLlkks.kswkkRyfvLfn..dvLlyykdsk.kkpkgsipLs
                       i  G ++++s+k+ + R++ L++++  L++yk + ++k    + +
   C28C12.10   897    SIVFGRVYLRSrKTETVRHALLRRddLKLVFYKAELdSKSVLELLIY 943

                   gcqvek.pd..kncFeirt.dr.........tlllqaeseeerkeWvkai
                   g+  +++p ++   Fe++++++ ++++++++++ ++ ++++++k+W +a+
   C28C12.10   944 GYFYREtPLddGWLFELVHrNQirtddtkddVISFRVDNSASAKKWSAAF 993

                   qsair<-*
                    + +
   C28C12.10   994 ADKLE    998



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