Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/C33D12.2
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Query:  C33D12.2  CE04765    status:Partially_confirmed TR:Q22904 protein_id:AAK39203.1

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N
--------   -----------                                  -----    ------- ---
DUF21      Domain of unknown function DUF21             207.6    6.7e-59   1
CBS        CBS domain                                    15.6      0.016   1
PAAD_DAPIN PAAD/DAPIN/Pyrin domain                        4.1        9.5   1
Corona_S2  Coronavirus S2 glycoprotein                    1.4        8.6   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
DUF21        1/1     142   318 ..     1   198 []   207.6  6.7e-59
PAAD_DAPIN   1/1     421   441 ..    71    92 .]     4.1      9.5
Corona_S2    1/1     425   469 ..   114   164 ..     1.4      8.6
CBS          1/1     413   474 ..     1    54 []    15.6    0.016

Alignments of top-scoring domains:
DUF21: domain 1 of 1, from 142 to 318: score 207.6, E = 6.7e-59
                   *->ilelliiliLillsafFSasEfalvslrkvrleqlaksGnkkaklal
                      +l+++++liL+++s++FS+++++l++l++++l+++++sG++++k+ +
    C33D12.2   142    WLSWICLLILLCFSGLFSGLNLGLMTLSPYELQLYIASGTEQEKRDA 188

                   klierldrylsavligitlvnilagilgeplldrllgplfknslseslah
                     i +++++ +++l++++++n+++++++++l+d+l g
    C33D12.2   189 GRILPIRKKGNQLLCTLLIGNVVVNVGVSLLMDQLVG------------- 225

                   dlsfalalgisTfLivvfGEiiPKtiAiqnaervalltappliffyllft
                     s++ +l+ +T++ivvfGEiiP++++++ ++ ++++t+p+ +++++l++
    C33D12.2   226 --SGFAVLVAATSCIVVFGEIIPQALCVKLGLPIGARTIPITQVLLFLMY 273

                   PlvwllnlianillrlfgvkpkdehdfalteeeLrilvsesa.eaGeldq
                   Pl+w+++++++i+l+++  ++       l++++L++++++s++++ + ++
    C33D12.2   274 PLTWPISKVLDIFLKEELTRS-------LERNKLVEMLKLSEkSIIGGQS 316

                   dE<-*
                   dE
    C33D12.2   317 DE    318

PAAD_DAPIN: domain 1 of 1, from 421 to 441: score 4.1, E = 9.5
                   *->rvledipnlrlLAeqLkkekek<-*
                      rvl d+p lr++ e+ k+++ +
    C33D12.2   421    RVLVDMP-LRNMLEEFKRGEYH    441

Corona_S2: domain 1 of 1, from 425 to 469: score 1.4, E = 8.6
                   *->smelnsmltvskpaglnLAtvssFngdelldPiynlsllltdSvlGG
                      +m l +ml   k++++  A+v++    e  dPiy l +l+t
    C33D12.2   425    DMPLRNMLEEFKRGEYHMALVERLVEQEDKDPIYELCGLIT------ 465

                   Lkdl<-*
                   L+d+
    C33D12.2   466 LEDI    469

CBS: domain 1 of 1, from 413 to 474: score 15.6, E = 0.016
                   *->dimtrdvvtvspdttleealelmrengisrlPVvded........gk
                       i +++v  v  d++l+  le +++  +++++V    +++++++  +
    C33D12.2   413    SIYNHEVRRVLVDMPLRNMLEEFKRGEYHMALVERLVeqedkdpiYE 459

                   lvGivtlrDllralv<-*
                   l G++tl+D++++++
    C33D12.2   460 LCGLITLEDIIEEII    474



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