Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/C34F6.10
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Query:  C34F6.10  CE15679   Fibronectin type III domain (4 domains) status:Partially_confirmed TR:O17637 protein_id:CAB03937.1

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
fn3      Fibronectin type III domain                    120.5    2.4e-33   6
DUF371   Domain of unknown function (DUF371)              4.4        6.9   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
fn3        1/6     219   237 ..    58    76 ..     1.3       63
fn3        2/6     260   342 ..     1    84 []    24.2  1.5e-05
fn3        3/6     355   434 ..     1    84 []    29.9  3.6e-07
fn3        4/6     714   740 ..    59    84 .]     5.5      3.9
fn3        5/6     752   839 ..     1    84 []    46.5  5.9e-12
DUF371     1/1     903   918 ..   123   139 .]     4.4      6.9
fn3        6/6     861   929 ..    14    84 .]    13.0    0.026

Alignments of top-scoring domains:
fn3: domain 1 of 6, from 219 to 237: score 1.3, E = 63
                   *->ytltgLkPgteYevrVqAv<-*
                      + ++ L P+t+Y++  +Av
    C34F6.10   219    FRVQSLHPNTTYKINMKAV    237

fn3: domain 2 of 6, from 260 to 342: score 24.2, E = 1.5e-05
                   *->PsaPtnltvtdvtstsltlsWsppt.gngpitgYevtyRqpkngge.
                      P +Pt + + +++   + l W+ + ++++ i++Y v y  ++n+ e+
    C34F6.10   260    PEPPTEVEILSRGLHFIELVWKTAInNGAFISHYHV-Y-IHENELEd 304

                   wneltvpgtttsytltgLkPgteYevrVqAvnggG.GpeS<-*
                    +  +    +   ++++L P t Y++r++++n+ G+++e
    C34F6.10   305 GRMMQTAEEK--IQISNLIPQTCYKIRIHSINALGeSMEG    342

fn3: domain 3 of 6, from 355 to 434: score 29.9, E = 3.6e-07
                   *->PsaPtnltvtdvtstsltlsWspptgngpitgYevtyRqpknggewn
                      P aP+n++v +++  s+++sW++          ev y + +++g+
    C34F6.10   355    PLAPENISVFAQSHRSIRVSWDKN--PNCTIWIEV-YNCASGKGGYA 398

                   eltvpgtttsytltgLkPgteYevrVqAvnggG.GpeS<-*
                   + +  g++   ++  L P+teY++rV+A+n+ G+G+
    C34F6.10   399 RENFGGDQ--TVIGELDPDTEYQMRVIARNEFGeGHSE    434

fn3: domain 4 of 6, from 714 to 740: score 5.5, E = 3.9
                   *->tltgLkPgteYevrVqAvnggG.GpeS<-*
                      +l   +Pg +Y+v++++++++G+++
    C34F6.10   714    VLDSVQPGEKYSVTLISLTTVGkSKQR    740

fn3: domain 5 of 6, from 752 to 839: score 46.5, E = 5.9e-12
                   *->PsaPtnltvtdvtstsltlsWsppt.gngpitgYevtyRqpkngge.
                      PsaP+++ v+ v+ +  t+sW++++++++pi gY v  R +  +ge
    C34F6.10   752    PSAPEDVAVSQVQIDRCTVSWTAAEgNGSPIIGYVV--R-MMLNGEl 795

                   ..wneltvpgttt..sytltgLkPgteYevrVqAvnggG.GpeS<-*
                    +++ +t + ++t+ +++l+ L P+teY + ++A n +G ++
    C34F6.10   796 fsEHFVTESENETnyRHVLKYLDPNTEYLINIAAKNSVGfSEKI    839

DUF371: domain 1 of 1, from 903 to 918: score 4.4, E = 6.9
                   *->VerLkdpGteLtveiiV<-*
                      V+ Lk+ +t  +++++V
    C34F6.10   903    VKSLKE-NTKYVFKLRV    918

fn3: domain 6 of 6, from 861 to 929: score 13.0, E = 0.026
                   *->stsltlsWspptgngpitgYevtyRqpknggewneltvpgtttsytl
                      +t l ++W++ t +g    Y++    +kn ++ + +   ++t  + +
    C34F6.10   861    ATALKIHWDRVT-SGNSMMYKLMK-INKNAQQVTLYEGENNT--AKV 903

                   tgLkPgteYevrVqAvnggG..GpeS<-*
                   + Lk++t+Y+++++  +++++ + +S
    C34F6.10   904 KSLKENTKYVFKLRVSDRATgaSTWS    929



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