Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm1/seq/C34F6.10
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Query: C34F6.10 CE15679 Fibronectin type III domain (4 domains) status:Partially_confirmed TR:O17637 protein_id:CAB03937.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
fn3 Fibronectin type III domain 120.5 2.4e-33 6
DUF371 Domain of unknown function (DUF371) 4.4 6.9 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
fn3 1/6 219 237 .. 58 76 .. 1.3 63
fn3 2/6 260 342 .. 1 84 [] 24.2 1.5e-05
fn3 3/6 355 434 .. 1 84 [] 29.9 3.6e-07
fn3 4/6 714 740 .. 59 84 .] 5.5 3.9
fn3 5/6 752 839 .. 1 84 [] 46.5 5.9e-12
DUF371 1/1 903 918 .. 123 139 .] 4.4 6.9
fn3 6/6 861 929 .. 14 84 .] 13.0 0.026
Alignments of top-scoring domains:
fn3: domain 1 of 6, from 219 to 237: score 1.3, E = 63
*->ytltgLkPgteYevrVqAv<-*
+ ++ L P+t+Y++ +Av
C34F6.10 219 FRVQSLHPNTTYKINMKAV 237
fn3: domain 2 of 6, from 260 to 342: score 24.2, E = 1.5e-05
*->PsaPtnltvtdvtstsltlsWsppt.gngpitgYevtyRqpkngge.
P +Pt + + +++ + l W+ + ++++ i++Y v y ++n+ e+
C34F6.10 260 PEPPTEVEILSRGLHFIELVWKTAInNGAFISHYHV-Y-IHENELEd 304
wneltvpgtttsytltgLkPgteYevrVqAvnggG.GpeS<-*
+ + + ++++L P t Y++r++++n+ G+++e
C34F6.10 305 GRMMQTAEEK--IQISNLIPQTCYKIRIHSINALGeSMEG 342
fn3: domain 3 of 6, from 355 to 434: score 29.9, E = 3.6e-07
*->PsaPtnltvtdvtstsltlsWspptgngpitgYevtyRqpknggewn
P aP+n++v +++ s+++sW++ ev y + +++g+
C34F6.10 355 PLAPENISVFAQSHRSIRVSWDKN--PNCTIWIEV-YNCASGKGGYA 398
eltvpgtttsytltgLkPgteYevrVqAvnggG.GpeS<-*
+ + g++ ++ L P+teY++rV+A+n+ G+G+
C34F6.10 399 RENFGGDQ--TVIGELDPDTEYQMRVIARNEFGeGHSE 434
fn3: domain 4 of 6, from 714 to 740: score 5.5, E = 3.9
*->tltgLkPgteYevrVqAvnggG.GpeS<-*
+l +Pg +Y+v++++++++G+++
C34F6.10 714 VLDSVQPGEKYSVTLISLTTVGkSKQR 740
fn3: domain 5 of 6, from 752 to 839: score 46.5, E = 5.9e-12
*->PsaPtnltvtdvtstsltlsWsppt.gngpitgYevtyRqpkngge.
PsaP+++ v+ v+ + t+sW++++++++pi gY v R + +ge
C34F6.10 752 PSAPEDVAVSQVQIDRCTVSWTAAEgNGSPIIGYVV--R-MMLNGEl 795
..wneltvpgttt..sytltgLkPgteYevrVqAvnggG.GpeS<-*
+++ +t + ++t+ +++l+ L P+teY + ++A n +G ++
C34F6.10 796 fsEHFVTESENETnyRHVLKYLDPNTEYLINIAAKNSVGfSEKI 839
DUF371: domain 1 of 1, from 903 to 918: score 4.4, E = 6.9
*->VerLkdpGteLtveiiV<-*
V+ Lk+ +t +++++V
C34F6.10 903 VKSLKE-NTKYVFKLRV 918
fn3: domain 6 of 6, from 861 to 929: score 13.0, E = 0.026
*->stsltlsWspptgngpitgYevtyRqpknggewneltvpgtttsytl
+t l ++W++ t +g Y++ +kn ++ + + ++t + +
C34F6.10 861 ATALKIHWDRVT-SGNSMMYKLMK-INKNAQQVTLYEGENNT--AKV 903
tgLkPgteYevrVqAvnggG..GpeS<-*
+ Lk++t+Y+++++ +++++ + +S
C34F6.10 904 KSLKENTKYVFKLRVSDRATgaSTWS 929