Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm1/seq/C34F6.8
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Query: C34F6.8 CE15677 Isocitrate and isopropylmalate dehydrogenases status:Partially_confirmed TR:O17643 protein_id:CAB03943.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
isodh Isocitrate/isopropylmalate dehydrogenase 354.0 6.8e-105 1
DUF135 Protein of unknown function DUF135 7.8 0.41 1
wnt wnt family 1.1 5.2 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
DUF135 1/1 111 131 .. 358 378 .] 7.8 0.41
wnt 1/1 136 146 .. 1 11 [. 1.1 5.2
isodh 1/1 28 424 .. 1 404 [] 354.0 6.8e-105
Alignments of top-scoring domains:
DUF135: domain 1 of 1, from 111 to 131: score 7.8, E = 0.41
*->ikriYrsttdrIrelLkGglw<-*
+k+ +s ++ Ir++L+G+ +
C34F6.8 111 LKKMWLSPNGTIRNILGGTVF 131
wnt: domain 1 of 1, from 136 to 146: score 1.1, E = 5.2
*->lCrslPGLspr<-*
lC+++P+L+p+
C34F6.8 136 LCKNIPRLVPG 146
isodh: domain 1 of 1, from 28 to 424: score 354.0, E = 6.8e-105
*->kIavLpGDGIGPEvmeaalkVLkavgekaggelefefeeglvGgaai
k+ +D G+E++++++k +k+++++++ l ++++++++G +++
C34F6.8 28 KVDNPVVDLDGDEMTRIIWKEIKNKLILPY--LDLDIKYYDLGLEYR 72
DetGiepLPeETleackeaCdavLlGAvgGPkggWDtltpkevRPEnsGL
Det+ ++++ +++ a++e +++++A+++P+ e R ++ L
C34F6.8 73 DETN-DQVTIDAAHAILEH-SVGIKCATITPD---------EARIKEFNL 111
LaLRKeLdGLfANlRPvkvfspslgdaSPlkreiveggvDiviVRELTGG
++++ +++G+++N++ ++vf+++++++++++ ++++++ i i+R+++G+
C34F6.8 112 KKMWLSPNGTIRNILGGTVFREPILCKNIPR-LVPGWTQPITIGRHAFGD 160
iYfGipkgikggkklikflk.........eelv.sgnfgeevavdtklYs
+Y ++ +i + ++l+ ++++++ + ++ +f ++++v++ +Y+
C34F6.8 161 QYKCTDLVIPS----GSTLQllvnkpdgsKDVHnVYDFKKSGGVGLAMYN 206
rdE.ieRIarvAFelArkrgprkkVtsvdKaNVLksSrGAFKlWretvee
+dE+i+ +a++ F++A+ + ++++++++K+++Lk+++G ++++++++
C34F6.8 207 TDEsIKGFAHSCFQYALMK--QWPLYLSTKNTILKKYDG---RFKDIFQD 251
vakknkkskfeYPdveLeHmlvDnaamqLvknPkqFDfViVTeNlFGDIL
+++k++ f+ ++++eH+l+D+ ++q++k+ ++fV++++N++GD++
C34F6.8 252 IYEKKYEADFKNNKIWYEHRLIDDQVAQALKSS--GGFVWACKNYDGDVQ 299
SDeASmltGSLGmlPSASlgaepdtsgfalyEPvHGSAPDIAGKgkKG.E
SD ++++GSLG++ S+ +++ ++++++E++HG+++++++ ++KG+
C34F6.8 300 SDIVAQGYGSLGLMSSVLMCPD---GKTIEAEAAHGTVTRHYREHQKGnS 346
TSANPiAtILSaAMMLRyS..lgleeaAL.dF.daiEaAVlktLeeGGir
TS+NPiA+I+++ ++L +++ l+ +ea L+ F+ +E+A++ t+ee G++
C34F6.8 347 TSTNPIASIFAWTRGLHHRgvLDNNEA-LkTFsLTLEKACIDTVEE-GKM 394
TgDLggeadGa.......kyvsTsemgdav<-*
T+DL + +G +++++++ y+ T+++ a+
C34F6.8 395 TKDLSICIHGTkkgtekgAYLITEDFLSAI 424