Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/C34F6.8
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Query:  C34F6.8  CE15677   Isocitrate and isopropylmalate dehydrogenases status:Partially_confirmed TR:O17643 protein_id:CAB03943.1

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
isodh    Isocitrate/isopropylmalate dehydrogenase       354.0   6.8e-105   1
DUF135   Protein of unknown function  DUF135              7.8       0.41   1
wnt      wnt family                                       1.1        5.2   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
DUF135     1/1     111   131 ..   358   378 .]     7.8     0.41
wnt        1/1     136   146 ..     1    11 [.     1.1      5.2
isodh      1/1      28   424 ..     1   404 []   354.0 6.8e-105

Alignments of top-scoring domains:
DUF135: domain 1 of 1, from 111 to 131: score 7.8, E = 0.41
                   *->ikriYrsttdrIrelLkGglw<-*
                      +k+  +s ++ Ir++L+G+ +
     C34F6.8   111    LKKMWLSPNGTIRNILGGTVF    131

wnt: domain 1 of 1, from 136 to 146: score 1.1, E = 5.2
                   *->lCrslPGLspr<-*
                      lC+++P+L+p+
     C34F6.8   136    LCKNIPRLVPG    146

isodh: domain 1 of 1, from 28 to 424: score 354.0, E = 6.8e-105
                   *->kIavLpGDGIGPEvmeaalkVLkavgekaggelefefeeglvGgaai
                      k+    +D  G+E++++++k +k+++++++  l ++++++++G +++
     C34F6.8    28    KVDNPVVDLDGDEMTRIIWKEIKNKLILPY--LDLDIKYYDLGLEYR 72

                   DetGiepLPeETleackeaCdavLlGAvgGPkggWDtltpkevRPEnsGL
                   Det+ ++++ +++ a++e   +++++A+++P+         e R  ++ L
     C34F6.8    73 DETN-DQVTIDAAHAILEH-SVGIKCATITPD---------EARIKEFNL 111

                   LaLRKeLdGLfANlRPvkvfspslgdaSPlkreiveggvDiviVRELTGG
                   ++++ +++G+++N++ ++vf+++++++++++ ++++++  i i+R+++G+
     C34F6.8   112 KKMWLSPNGTIRNILGGTVFREPILCKNIPR-LVPGWTQPITIGRHAFGD 160

                   iYfGipkgikggkklikflk.........eelv.sgnfgeevavdtklYs
                   +Y  ++ +i +     ++l+   ++++++  + ++ +f ++++v++ +Y+
     C34F6.8   161 QYKCTDLVIPS----GSTLQllvnkpdgsKDVHnVYDFKKSGGVGLAMYN 206

                   rdE.ieRIarvAFelArkrgprkkVtsvdKaNVLksSrGAFKlWretvee
                   +dE+i+ +a++ F++A+ +  ++++++++K+++Lk+++G   ++++++++
     C34F6.8   207 TDEsIKGFAHSCFQYALMK--QWPLYLSTKNTILKKYDG---RFKDIFQD 251

                   vakknkkskfeYPdveLeHmlvDnaamqLvknPkqFDfViVTeNlFGDIL
                   +++k++   f+  ++++eH+l+D+ ++q++k+   ++fV++++N++GD++
     C34F6.8   252 IYEKKYEADFKNNKIWYEHRLIDDQVAQALKSS--GGFVWACKNYDGDVQ 299

                   SDeASmltGSLGmlPSASlgaepdtsgfalyEPvHGSAPDIAGKgkKG.E
                   SD  ++++GSLG++ S+  +++   ++++++E++HG+++++++ ++KG+
     C34F6.8   300 SDIVAQGYGSLGLMSSVLMCPD---GKTIEAEAAHGTVTRHYREHQKGnS 346

                   TSANPiAtILSaAMMLRyS..lgleeaAL.dF.daiEaAVlktLeeGGir
                   TS+NPiA+I+++ ++L +++ l+ +ea L+ F+  +E+A++ t+ee G++
     C34F6.8   347 TSTNPIASIFAWTRGLHHRgvLDNNEA-LkTFsLTLEKACIDTVEE-GKM 394

                   TgDLggeadGa.......kyvsTsemgdav<-*
                   T+DL  + +G +++++++ y+ T+++  a+
     C34F6.8   395 TKDLSICIHGTkkgtekgAYLITEDFLSAI    424



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