Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/C45B11.3
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Query:  C45B11.3  CE05427  locus:dhs-18 alcohol dehydrogenase status:Partially_confirmed TR:Q18639 protein_id:CAA98431.1

Scores for sequence family classification (score includes all domains):
Model     Description                                   Score    E-value  N
--------  -----------                                   -----    ------- ---
adh_short short chain dehydrogenase                     139.0    2.8e-38   2
cystatin  Cystatin domain                                 4.6        4.8   1

Parsed for domains:
Model     Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------  ------- ----- -----    ----- -----      -----  -------
cystatin    1/1      73    95 ..     1    26 [.     4.6      4.8
adh_short   1/2      12   155 ..     1   143 [.   138.5  3.7e-38
adh_short   2/2     169   201 ..   156   190 ..     1.0       31

Alignments of top-scoring domains:
cystatin: domain 1 of 1, from 73 to 95: score 4.6, E = 4.8
                   *->GglspaddNendpevqeaadfAvaey<-*
                      +++++++d   +  v+ a+d+Av+++
    C45B11.3    73    PCVVDVRD---EAAVKAAVDAAVKKF    95

adh_short: domain 1 of 2, from 12 to 155: score 138.5, E = 3.7e-38
                   *->tgKvaLvTGassGIGlaiAkrLakeGakVvvvdrreekae.......
                      +gK++ +TGas+GIG++iA+ Lak+Ga++vv++ ++    + +++
    C45B11.3    12    AGKTVFITGASRGIGKEIALKLAKDGANIVVAAKTATAHPklpgtiy 58

                   qvaaelkaelGdralfiqlDvtdeeqvkaavaqaverlGdrlDvLVNNAG
                   ++aae+++++G  al++++Dv+de++vkaav++av+++G ++D+L+NNA
    C45B11.3    59 TAAAEIEKAGG-HALPCVVDVRDEAAVKAAVDAAVKKFG-GIDILINNAS 106

                   ilgdgppfeelseedwervidvNltGvflltravlpamdhmlkrkgGrIv
                        +  e+ +++ ++ +  +N +G++llt+++lp    ++k+k   +
    C45B11.3   107 AIS-LTNTEDTDMKRYDLMHSINTRGTYLLTKTCLP---YLKKGKNPHVL 152

                   Nis<-*
                   Nis
    C45B11.3   153 NIS    155

adh_short: domain 2 of 2, from 169 to 201: score 1.0, E = 31
                   *->saYsASKaavigltrsLAlElaphgtgIrVnavaP<-*
                      ++Y+ +K+++ +   + + E++p+g  I Vna +P
    C45B11.3   169    VGYTMAKFGMSMCVLGHHEEFRPYG--IAVNALWP    201



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