Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/C46A5.4
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Query:  C46A5.4  CE27858   peroxidase status:Partially_confirmed TR:Q18647 protein_id:AAB03144.2

Scores for sequence family classification (score includes all domains):
Model         Description                               Score    E-value  N
--------      -----------                               -----    ------- ---
An_peroxidase Animal haem peroxidase                   1466.4          0   2
vwc           von Willebrand factor type C domain         7.2          1   1
LEF-9         Late expression factor 9 (LEF-9)            2.9          4   1

Parsed for domains:
Model         Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------      ------- ----- -----    ----- -----      -----  -------
LEF-9           1/1      49    74 ..     1    26 [.     2.9        4
An_peroxidase   1/2      76   612 ..     1   596 []   582.9 2.1e-171
An_peroxidase   2/2     788  1328 ..     1   596 []   886.5 8.3e-263
vwc             1/1    1365  1389 ..     1    33 [.     7.2        1

Alignments of top-scoring domains:
LEF-9: domain 1 of 1, from 49 to 74: score 2.9, E = 4
                   *->mvsFvnKeptefdLLlDpnkldnvvf<-*
                      m++F++ e t++  +  +n+++++v+
     C46A5.4    49    MIQFLPTENTKMKEICPVNQIEECVI    74

An_peroxidase: domain 1 of 2, from 76 to 612: score 582.9, E = 2.1e-171
                   *->rYRtlDGtCNNlenPtwGaanspfrRllpPsYdDGidaPRsrsvdgs
                      +YR+++G CNN +nP  Ga++ ++ R+lp++Y+DGi+aPRs s++g+
     C46A5.4    76    KYRSYTGHCNNVKNPLNGASYERLKRFLPADYSDGISAPRS-SKSGQ 121

                   pLPsaRvvSrkllsdrdfpipdpkfgtTlmvmqfGQFmaHDitktssst.
                   pLPs+R +S ++  +      +      l+ + f  F++ Di++ +s++
     C46A5.4   122 PLPSSRALSALFTPSPS-G--HATC--SLLIAPFLSFIYDDIVHVPSNRi 166

                   .......sPiEengealeCckcdspvspqlshpeCfPIpvppdDPffgql
                    +++  ++   +++ +l+Cc+ d      +shpeCf+Ipvp+dD  +
     C46A5.4   167 fkrdfygN---DKAMPLPCCRGD------NSHPECFEIPVPEDDT-LQSK 206

                   gvrClpFvRSlpaprtgpqcrlGgpReQlNqaTayiDaSpiYGssaeear
                   +v+Clp+ RSlp+p   p+c + g+R+Q N++T+y+D+S+iYGs++   +
     C46A5.4   207 NVKCLPYSRSLPVPN--PKCSF-GQRQQANMVTSYLDLSQIYGSTEGIVK 253

                   klRaFqgGlLktspdnggpvrlgrdllPldentqdcgsCvyprsaagsgC
                   k+R+ ++G+L   + +g    lg   +P++ +     s +  rs++g++C
     C46A5.4   254 KMRLHKNGKLALRAVGGFNNQLG--VPPANLD----SSIC--RSSTGKPC 295

                   fiaGDdRvnlqpgLaaLHtLflREHNRiAdaLkalNPhWdDErlFQEARk
                    +aG +  n+ p+  a+ t++ R+HN iAd+L+ +NPhWdD+++F+EAR+
     C46A5.4   296 LLAGNNKINFLPTSGAIYTIWMRQHNVIADKLASVNPHWDDQKVFEEARR 345

                   IviAqmQhItynEyLPilLGrelmkkMrANWyGLLGfgLvygplksGyVg
                   I iAq+QhIt+nE +P+l G+e ++            g +  ++k+G
     C46A5.4   346 ITIAQFQHITFNEMVPVLVGKEQLRV----------MGIK--LQKNG--- 380

                   yyngYdpnvQYnpsianEFatAAFRfGHslipgkfplvdendkiyfgkpi
                   y+ gYd n+  + s +n Fa+AA  f+ +l+p+ f++ d+      + +
     C46A5.4   381 YDSGYDINI--DSSASNVFASAAGQFFLTLLPSQFNIEDKR-----FSTK 423

                   snlsgsvrLsdlffnpselylilaeggvdqllrGlatqpaGrmLnrvDrf
                   s+     +L  +f++p+ +y+   +g +d +l  l++ p+  +  +   +
     C46A5.4   424 SE-----SLLKHFNDPALIYE---KGRIDGMLKFLLNAPI--E--KPGLH 461

                   itdevtnkLFgtrgeppfglDLasinIqRGRDhGlpsYNeyRefCGLpra
                    +++++  + +++     ++D ++  Iq GRDhGlpsY ++R fC L
     C46A5.4   462 SSPLLRTAFQKKD--IADSVDIIAMVIQMGRDHGLPSYLQWRTFCKLDDF 509

                   tsFeDLtdlispdeenlarLkslYendvdDvDLyVGgllEkpvpGglvGp
                    sF  L + + p  +n+   ++lYe +++D+D++VGgl+E+p +G+l+Gp
     C46A5.4   510 SSFLALQTIFKP-SVNISDFERLYE-SPEDIDVFVGGLSEQPTKGSLLGP 557

                   TfaCIiaeQFqRlrrGDRFwYEngrgkpsgFTpeVQLaeiRKtsLarliC
                   TfaC +a Q++ ++rGDRFwYEn    ps FT + Q++eiRKt++ar+iC
     C46A5.4   558 TFACLFAHQMAQTKRGDRFWYENF-VSPSAFTVD-QIDEIRKTTMARIIC 605

                   dNtdvlt<-*
                   dNtd  t
     C46A5.4   606 DNTDTVT    612

An_peroxidase: domain 2 of 2, from 788 to 1328: score 886.5, E = 8.3e-263
                   *->rYRtlDGtCNNlenPtwGaanspfrRllpPsYdDGidaPRsrsvdgs
                      +YRt+ G+CNNl+nP +G+a++ +rRll P+YdDG+d+PR+rsv gs
     C46A5.4   788    KYRTYSGWCNNLKNPKFGNAFTQMRRLLDPAYDDGFDTPRTRSVLGS 834

                   pLPsaRvvSrkllsdrdfpipdpkfgtTlmvmqfGQFmaHDitktsssts
                   +LPsaR +S+ ++sd+    +++kf  T+m+mqfGQ ++HD+ +++ s++
     C46A5.4   835 ELPSARKISNIVHSDAP--KFHVKF--THMLMQFGQILDHDMMHSPISRG 880

                   PiEengealeCckcdspvspqlshpeCfPIpvppdDPffgq....lgvrC
                      +++++l+C++cds    q+ + +CfPI+++++DPff  ++++ + rC
     C46A5.4   881 ---PKNTILNCSSCDSA---QTLSIHCFPIKIEANDPFFPSkhsdGRPRC 924

                   lpFvRSlpaprtgpqcrlGgpReQlNqaTayiDaSpiYGssaeearklRa
                   +pF+RSl+a     q  l g+R+QlNq+T+++DaS iYGs+ +ea+klR+
     C46A5.4   925 MPFARSLLA-----QVSL-GFRNQLNQLTSFLDASTIYGSTQCEANKLRL 968

                   FqgGlLktspdnggpvrlgrdllPldentqdcgsCvyprsaagsgCfiaG
                   F +G+L +++ + +   l+   + ++e   dc+s+    +++  +Cf+aG
     C46A5.4   969 FSDGKLNFTDLGFNKEALP---QGNQER--DCRSVL---QNRQRRCFVAG 1010

                   DdRvnlqpgLaaLHtLflREHNRiAdaLkalNPhWdDErlFQEARkIviA
                   D+R n+qpgL+a+H +flREHNRiA+ Lk++N  W+DE+lFQE+R+I+iA
     C46A5.4  1011 DERSNEQPGLTAIHNIFLREHNRIARYLKQINNFWSDEKLFQESRRINIA 1060

                   qmQhItynEyLPilLGrelmkkMrANWyGLLGfgLvygplksGyVgyyng
                   q+QhI+y E+LP++LG ++m+k           gL   p+++G   y++g
     C46A5.4  1061 QLQHIIYKEWLPVVLGCQNMEK----------WGLM--PQTAG---YFEG 1095

                   YdpnvQYnpsianEFatAAFRfGHslipgkfplvdendkiyfgkpisnls
                   Yd ++  +++i++E +t+AFRfGHsli+g f++++ n     +++++n
     C46A5.4  1096 YDDQC--DATISQEMSTSAFRFGHSLIRGVFTRMNDN-----FQNMTN-- 1136

                   gsvrLsdlffnpselylilaeggvdqllrGlatqpaGrmLnrvDrfitde
                     v+L ++f nps +y+ + +g ++++l+Gl + ++  m  ++Dr+i  +
     C46A5.4  1137 -HVNLTETFSNPSPVYD-KNSGHMESILMGLIGANS--M--AFDRHIVTA 1180

                   vtnkLFgtrgeppfglDLasinIqRGRDhGlpsYNeyRefCGLpratsFe
                   v+n+LF ++g p +glDL ++nIqRGRDhG+++YN+yR++CGL++a  F
     C46A5.4  1181 VRNHLFAKPGGPLTGLDLPAVNIQRGRDHGVQGYNAYRKHCGLRKASAFS 1230

                   DLtdlispdeenlarLkslYendvdDvDLyVGgllEkpvpGglvGpTfaC
                   DL d++++  e +++L+++Y+ +vdD+DL++G+++E p +G+lvGpT+aC
     C46A5.4  1231 DLRDVMNS--EAVTALETAYA-HVDDIDLFPGIMSESPTRGSLVGPTLAC 1277

                   IiaeQFqRlrrGDRFwYEngrgkpsgFTpeVQLaeiRKtsLarliCdNtd
                    i+eQ+qRl+++DRF+YE   +  + FTp+ QL eiRK+sL+r+iCdN+
     C46A5.4  1278 LIGEQMQRLKKCDRFYYETS-DSMVRFTPD-QLVEIRKASLSRIICDNSE 1325

                   vlt<-*
                   + +
     C46A5.4  1326 YAA    1328

vwc: domain 1 of 1, from 1365 to 1389: score 7.2, E = 1
                   *->CvqnGvvYengetWkpdsqPnGvdkCtyiCtCd<-*
                      C+++++v + g+t ++ +       C+ +CtC+
     C46A5.4  1365    CLVDERVVNRGKTKRITP-------CI-TCTCT    1389



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