Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm1/seq/C46H11.2
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: C46H11.2 CE08784 status:Partially_confirmed TR:Q9GYJ1 protein_id:AAF99881.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
FMO-like Flavin-binding monooxygenase-like 78.7 8.1e-21 1
pyr_redox Pyridine nucleotide-disulphide oxidored 48.1 4.2e-13 4
TrkA-N TrkA-N domain 11.5 0.11 2
Amino_oxidase Flavin containing amine oxidoreductase 10.4 0.055 1
NAD_Gly3P_dh NAD-dependent glycerol-3-phosphate dehy 8.1 0.21 1
ThiF ThiF family 5.1 4.7 1
DAO FAD dependent oxidoreductase 5.1 2 2
Octopine_DH_N NAD/NADP octopine/nopaline dehydrogenas 4.6 3.7 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
DAO 1/2 3 15 .. 1 13 [. 6.7 0.7
Octopine_DH_N 1/1 2 18 .. 1 17 [. 4.6 3.7
NAD_Gly3P_dh 1/1 2 19 .. 1 18 [. 8.1 0.21
ThiF 1/1 1 19 [. 1 19 [. 5.1 4.7
TrkA-N 1/2 4 30 .. 1 27 [. 8.0 1
Amino_oxidase 1/1 12 39 .. 1 27 [. 10.4 0.055
pyr_redox 1/4 4 40 .. 1 48 [. 30.7 4.4e-08
pyr_redox 2/4 77 139 .. 207 284 .. 2.9 4.4
DAO 2/2 171 179 .. 1 9 [. 1.7 16
FMO-like 1/1 3 198 .. 1 212 [. 78.7 8.1e-21
pyr_redox 3/4 156 199 .. 156 200 .. 7.8 0.17
TrkA-N 2/2 172 201 .. 1 30 [. 3.9 14
pyr_redox 4/4 210 245 .. 100 131 .. 3.7 2.6
Alignments of top-scoring domains:
DAO: domain 1 of 2, from 3 to 15: score 6.7, E = 0.7
*->mdvvVIGgGViGl<-*
++v VIG+G++Gl
C46H11.2 3 KRVCVIGAGAAGL 15
Octopine_DH_N: domain 1 of 1, from 2 to 18: score 4.6, E = 3.7
*->mltVgvLGaGnagtalA<-*
++ V v+GaG ag+a A
C46H11.2 2 PKRVCVIGAGAAGLAAA 18
NAD_Gly3P_dh: domain 1 of 1, from 2 to 19: score 8.1, E = 0.21
*->pkkvtVlGaGaWGTAlAk<-*
pk+v+V+GaGa G A Ak
C46H11.2 2 PKRVCVIGAGAAGLAAAK 19
ThiF: domain 1 of 1, from 1 to 19: score 5.1, E = 4.7
*->knskVLvvGaGGLGsealk<-*
++V+v+GaG+ G +a+k
C46H11.2 1 MPKRVCVIGAGAAGLAAAK 19
TrkA-N: domain 1 of 2, from 4 to 30: score 8.0, E = 1
*->hfiviGlGrvGrsvakeLleeGhdVvv<-*
+++viG+G+ G++ ak l++G +V v
C46H11.2 4 RVCVIGAGAAGLAAAKHSLAQGLEVEV 30
Amino_oxidase: domain 1 of 1, from 12 to 39: score 10.4, E = 0.055
*->laGLaAAreLlraGf.VtvlEArdRvGG<-*
aGLaAA++ l +G +V v+E + vGG
C46H11.2 12 AAGLAAAKHSLAQGLeVEVFEQTGNVGG 39
pyr_redox: domain 1 of 4, from 4 to 40: score 30.7, E = 4.4e-08
*->dvvIIGgGpAGlaAAiraaragflGrkrlkvalvEkepplkrgtlGG
+v++IG+G+AGlaAA++ + G l+v ++E+ g +GG
C46H11.2 4 RVCVIGAGAAGLAAAKHSLA---QG---LEVEVFEQT-----GNVGG 39
T<-*
T
C46H11.2 40 T 40
pyr_redox: domain 2 of 4, from 77 to 139: score 2.9, E = 4.4
*->lprkddeiaaalleklleegGievllgtkgvteiegdgdgglvegvk
lp+++ + + + +++ +g ++++ + v+ +e +d + +
C46H11.2 77 LPSFLTHENVREYLQEFSQG-MPIHFNQT-VENVERIDD----KWKV 117
vkvvktdgerdavedegeeleaDlVlvAiGr<-*
+ ++ e +D V+v+ G+
C46H11.2 118 TTHHGAG---------IDEHFFDIVFVCNGH 139
DAO: domain 2 of 2, from 171 to 179: score 1.7, E = 16
*->mdvvVIGgG<-*
++v+VIG+G
C46H11.2 171 KEVIVIGAG 179
FMO-like: domain 1 of 1, from 3 to 198: score 78.7, E = 8.1e-21
*->aKkVAVIGAGVSGLaSiKCCLeEGILEPtCFERSdDIGGLWrFtEnv
K+V VIGAG GLa +K L G LE+ FE + +GG+W +
C46H11.2 3 -KRVCVIGAGAAGLAAAKHSLAQG-LEVEVFEQTGNVGGTWVYSKQT 47
EeGrASiYKSvvtNvsKEMsCYSDFPfPedyPNFmhnskilEYLrmfAke
S Y +tN +KE +++ Pf + P F+ ++ + EYL++f
C46H11.2 48 GSHS-SMYQNMTTNLPKEVMQFRGVPFRNELPSFLTHENVREYLQEFSQG 96
FdLLKYIQFkTtVcSVkKrPDFstsGQWeVvTeseGKqesaVFDAVMVCT
I F tV +V + ++ W V+T ++ + FD V VC
C46H11.2 97 MP----IHFNQTVENV---ERIDD--KWKVTTHHGAGIDEHFFDIVFVCN 137
GhhtnPhLPLeSFPGiekFKGqyFHSrdYKhPegFlGKRVlVIGlGNSGg
Gh+ P+ P e +F G HS dY h +K V VIG G SG
C46H11.2 138 GHYFAPNNPYEE----SAFEGSFIHSHDYRHSKDYIDKEVIVIGAGPSGI 183
DiAvELSrtAeqVfl<-*
Di LS tA++ +l
C46H11.2 184 DISLQLSETAKKITL 198
[output cut off at A = 10 top alignments]