Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/C47D12.1
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Query:  C47D12.1  CE05429   Yeast YHP9 like status:Partially_confirmed TR:Q18667 protein_id:CAA93765.1

Scores for sequence family classification (score includes all domains):
Model           Description                             Score    E-value  N
--------        -----------                             -----    ------- ---
FAT             FAT domain                              731.2   4.4e-216   1
PI3_PI4_kinase  Phosphatidylinositol 3- and 4-kinase    218.9    7.5e-62   1
FATC            FATC domain                              45.4    1.1e-13   1
DUF577          Family of unknown function (DUF577)       6.6       0.98   1
Pox_F12L        Poxvirus F12L protein                     5.5       0.55   1
Vps26           Vacuolar protein sorting-associated p     5.4       0.49   1
SPK             Domain of unknown function (DUF545)       5.1        4.5   1
Carn_acyltransf Choline/Carnitine o-acyltransferase       1.7        8.3   1
wnt             wnt family                                0.6          8   1

Parsed for domains:
Model           Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------        ------- ----- -----    ----- -----      -----  -------
Carn_acyltransf   1/1     430   446 ..   658   674 .]     1.7      8.3
wnt               1/1     587   593 ..   346   352 .]     0.6        8
SPK               1/1     673   686 ..     1    14 [.     5.1      4.5
Vps26             1/1    1425  1462 ..     1    40 [.     5.4     0.49
Pox_F12L          1/1    1851  1880 ..   586   619 ..     5.5     0.55
DUF577            1/1    2217  2247 ..     1    31 [.     6.6     0.98
FAT               1/1    2685  3296 ..     1   722 []   731.2 4.4e-216
PI3_PI4_kinase    1/1    3592  3886 ..     1   335 []   218.9  7.5e-62
FATC              1/1    3912  3944 .]     1    33 []    45.4  1.1e-13

Alignments of top-scoring domains:
Carn_acyltransf: domain 1 of 1, from 430 to 446: score 1.7, E = 8.3
                   *->adrfakyLekaLldmrd<-*
                      ++r+ ++L ++L+ m +
    C47D12.1   430    SARLLNSLAESLCKMDS    446

wnt: domain 1 of 1, from 587 to 593: score 0.6, E = 8
                   *->vevhtCK<-*
                      +++htCK
    C47D12.1   587    YIMHTCK    593

SPK: domain 1 of 1, from 673 to 686: score 5.1, E = 4.5
                   *->aeltrfmdFLvekT<-*
                        +++ mdFL+e++
    C47D12.1   673    EIFEKYMDFLIERI    686

Vps26: domain 1 of 1, from 1425 to 1462: score 5.4, E = 0.49
                   *->FGppidIeIkldngeeRKtVev.ktedGkveknpvyedgEt<-*
                       ++ id  I+l  g+e+K++e+ + + +k++   vye++E+
    C47D12.1  1425    -KQYIDKGIEL--GDEHKMIEIlALRSSKITVDQVYESDES    1462

Pox_F12L: domain 1 of 1, from 1851 to 1880: score 5.5, E = 0.55
                   *->dlvnllerlfslllAllaelspssvlSAlfyaFA<-*
                      d  nl++rl s +  + ++ls+++v   +fy ++
    C47D12.1  1851    D--NLVARLTSVIDSHRNYLSDGMVI--VFYQLC    1880

DUF577: domain 1 of 1, from 2217 to 2247: score 6.6, E = 0.98
                   *->mreLqPLLIsCLkeegisesmfKvLgevVnh<-*
                      mr+Lq  LI CL        m +   ++V++
    C47D12.1  2217    MRQLQRPLIQCLNNGAQNFKMTRLVTQIVSR    2247

FAT: domain 1 of 1, from 2685 to 3296: score 731.2, E = 4.4e-216
                   *->llgeislkckayarallylEssirkkpgqaekektrepkva.....d
                      l+++is+k++++++++++lE++i+++p+q+++++ re+kva++  +d
    C47D12.1  2685    LIEFISSKHECWHTGIRLLENHIWTIPKQLNNTLLREMKVApglagD 2731

                   istlesLqeiYnsigepDslaGvlrrrarepidmR.m.sltqkilwyEkl
                   i+tlesL ++Yn+i+e+D++a++++rra +p++mR m++++++++++ ++
    C47D12.1  2732 IETLESLGTLYNEISEFDQFAAIWERRAVFPDTMRaMsAMQLGDMELAQS 2781

                   gtWedFFAlacYeeaekksdsgnTse.ektspeategeiksledlGewsq
                   +++++  + ++Ye+++++ +++nTs++ek++++++++e+++++++  +++
    C47D12.1  2782 YLEKS--MSSTYETLAPTINPNNTSNsEKHVSPIIDKEYDHWMEM--YIT 2827

                   llsklqkkWdvleylrnekddelaekysigleAalaaeaaWrlgdWnvee
                   ++s+l+ +W+++++++n+kd+++ +          +++aa++++dWnv+e
    C47D12.1  2828 NCSELL-QWQNVADVCNGKDMQHVR---------GLINAASHIPDWNVVE 2867

                   dsleqyvgsvmketsldkeaQlfraldlalrndefsetlyghiekardel
                   ++++q++g+++++++ld++  lf+++ +++++++++ ++++h++++++++
    C47D12.1  2868 ECKSQIAGCIPPSFHLDYT--LFNLM-STVMRMNEN-SSPTHMKERCKIA 2913

                   ineleelsaakwesypferaYkeHvslLvklqmlnELeesieiykklse.
                   i+e++e ++++w+++p + ++++Hv++L+ +++++E+ees++i+ +l e
    C47D12.1  2914 IQECTEAHISRWRALP-SVVSYGHVKILQAMNLVREIEESTDIRIALLEa 2962

                   pnqnnldsqlkdiK.lllgWrkRlpgcqdddvdiwepilalRrlvlspke
                   p+++ ++  + d+K+l++++r+R+p+++d d+ ++++++++R++++ ++
    C47D12.1  2963 PSNKVDQALMGDMKsLMKVFRNRTPTTSD-DMGFVSTWYDWRNQIHGMML 3011

                   qkleawlklasncrksgrkslsnavlarllgslqraspvsikakllhaae
                   q++e+w+k++ n+  +g     n++++++++++q++ +v   ak+++++
    C47D12.1  3012 QRFEYWDKVGLNVAATG-----NQSIVPIHSMAQAQLAV---AKHAKNLG 3053

                   vhnlpevlyeqlkllwakgmkdindelnelskllrelskcagyeqgnpkl
                   +hnl+++l+++l+ l+a++m+d++d+++++ k+lr+++++a++e++++
    C47D12.1  3054 FHNLTKDLLNKLAGLTAIPMMDAQDKVCTYGKTLRDMANSAADERVKN-- 3101

                   eelkvaLevvsltkaetlgsPflaetknkllkagelkkrfqsvlralste
                   e l++aLev++++   ++++ ++++++   + + +++ +++svl++
    C47D12.1  3102 ELLCEALEVLEDV---RIDD-LQKDQV---AALLYHRANIHSVLDQA--- 3141

                   ekalqayyeDatqldknwassgvveykawhkwGlfnfeavsksvlpllta
                   e+a++++++ a+ql ++++s++++++k +++wG++++++          +
    C47D12.1  3142 ENADYTFSA-ASQLVDLQNSVTTTGIKLMKNWGHHLYKR----------F 3180

                   fkralqeeqpkkehkgptagntsevesqessvspsldkkrnevkvklknq
                   f+++ ++e                                      ++n+
    C47D12.1  3181 FSTTVCKE--------------------------------------TGNN 3192

                   flvnAlrcfltslrlsnkvvdssklqdllrkitdLWLdkgdksdgeesgv
                   f ++Al+c+++++r++n+    +k++++++ki  LWL+k+++++g++
    C47D12.1  3193 FGRQALACYFIAARVDND----IKARKPIAKI--LWLSKHLNACGSH--- 3233

                   rklkfkrlesqikkllekinslvtkfitaiptynWLtvipQLisrlstkh
                                   e++n++++k+ ++++ +nWL+++pQL+++++  +
    C47D12.1  3234 ----------------EVMNRVIKKQLHSLNLFNWLYWLPQLVTDVR--Y 3265

                   penevvqrllmhilskialayPqallyqltaasks<-*
                   ++n++++    +il+k+a+a+P +++y++++a++
    C47D12.1  3266 KPNSNFV----LILCKMAAAHPLQVFYHIREAVSV    3296

PI3_PI4_kinase: domain 1 of 1, from 3592 to 3886: score 218.9, E = 7.5e-62
                   *->gyafifKgGdDlrsrqDervlQliaVFKPkDEEPyAplNPkgtkwsh
                      + af++K+        ++rv Q++
    C47D12.1  3592    SAAFYLKKSVQDE--PTNRVPQMF----------------------- 3613

                   GerlmnkllkgegldrrRnlqltaYlviplgsrsGlie............
                     ++++++l++++++ r     + ++ + l++r+G+  +  +  + ++
    C47D12.1  3614 --KHLDHVLQTDRESAR----RHLHAPTVLQMRVGQKTtlyevasvqpya 3657

                   ......wvpnattlaeipptyvvkksfkpfnysdfmraklkttn.qlsk.
                    +++ +  ++a ++++++p++v++++f+ ++y+d+m+ ++++++ q+s++
    C47D12.1  3658 mppdctRNYPASQIDIVHPYDVLTATFNGSYYPDDMVLHFFERFaQSSSs 3707

                   nakll.k.ehkdllqmapdrkqltllekvevFeealsntpkpgllqwFvk
                   ++++l++++++d+++++p++++++++++++++++a++++p+++l++++++
    C47D12.1  3708 IGQPLpTpTNQDGTVAPPRLTEAHHIKNIIYEDFARDMIPFRLLYDYLTA 3757

                   kfpdaapyeewfarfeeLtearknfvrScAgmsvldYiLgngDRHldNiL
                   ++pd+    +++a       ++k+  +S+A++s + Y+++++ +++d ++
    C47D12.1  3758 RYPDP---VMYYA-------MKKQLLHSLAVLSTIEYHCNLTPMGPDQMM 3797

                   vkkdkktGklfHIDFGlcfp..hskgkrgekpervPFrLTrWPQaklpfv
                   +  ++ tG l    + +   +++s + ++++ ++vPFrLT+      +++
    C47D12.1  3798 M--TMNTGVLSNPSYRFEIRggRSLHDIQHFGHEVPFRLTP------NLS 3839

                   eamggyiasLgpsgdeglFrelceeayralRrnlnlltnlLkqkavarGl
                    +        g+ +d +l++++     +++++++++++++L
    C47D12.1  3840 ILV-------GVAQDGDLLWSMAAASKCLMKKEPEVIMRPL--------V 3874

                   lmledglpdwrs<-*
                   ++ ++++ d+ +
    C47D12.1  3875 WDEFANNTDCDK    3886

FATC: domain 1 of 1, from 3912 to 3944: score 45.4, E = 1.1e-13
                   *->epLsvegqvedLIqqATspeNLarmYiGWcpfl<-*
                      +++ +++++++LI++A++++NLarm++++++++
    C47D12.1  3912    DAKLRKDDCVSLISRAKDSDNLARMPPTYHAWF    3944



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