Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/C47E12.3
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Query:  C47E12.3  CE05447   alpha-mannosidase status:Partially_confirmed TR:Q18679 protein_id:CAA93106.1

Scores for sequence family classification (score includes all domains):
Model          Description                              Score    E-value  N
--------       -----------                              -----    ------- ---
Glyco_hydro_47 Glycosyl hydrolase family 47             841.3   3.4e-249   1
DUF567         Protein of unknown function (DUF567)       4.9        3.5   1
CheD           CheD                                       4.6        9.3   1

Parsed for domains:
Model          Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------       ------- ----- -----    ----- -----      -----  -------
CheD             1/1      72    92 ..   110   130 .]     4.6      9.3
Glyco_hydro_47   1/1       1   451 [.     1   515 []   841.3 3.4e-249
DUF567           1/1     510   525 ..   179   194 .]     4.9      3.5

Alignments of top-scoring domains:
CheD: domain 1 of 1, from 72 to 92: score 4.6, E = 9.3
                   *->vlvrkvdggkadavkqeekvi<-*
                      + +++v ++k+ +v++ e +i
    C47E12.3    72    LVIKTVSFEKNTTVQVFESTI    92

Glyco_hydro_47: domain 1 of 1, from 1 to 451: score 841.3, E = 3.4e-249
                   *->MFqHAWdgYkkYAwghDELkPiscrgrkrd..dPsnlhssdifGesn
                      MFq++Wd+Y+++A+++DEL+Pi+crgr++d+++P+n++++d++G  +
    C47E12.3     1    MFQFGWDNYMEHAFPADELDPIHCRGRGHDhdNPDNINVNDVLG--D 45

                   lgaTivDaLDTLyiMGledEfreAvdwveetlsfdnplidstVsVFEtTI
                   +++ ++D+LD L+++G++dEf++Av++v++t+sf+   +++tV+VFE TI
    C47E12.3    46 YSLGLIDTLDSLVVFGDADEFKRAVNLVIKTVSFE---KNTTVQVFESTI 92

                   RvlGGLLSAYaLtgdpkk.lgdvegsdydkmLLkKAvdlAdrLLpAF.nT
                   Rv+GGLL+A++++ d+++++g++++sdy+++LL++A+dlA rLLpAF+ T
    C47E12.3    93 RVMGGLLAAHMIAADKTNrFGPFYMSDYGGELLTLAHDLAGRLLPAFdGT 142

                   ptGIPysrvNlksgvaknytwasggssilAefGTLlLEFtyLSrLTGdpt
                    tGIPy+r+Nl++g+ +++t+    s++++++G+LlLEF+ LS+L+Gd+t
    C47E12.3   143 ATGIPYTRINLQKGILPGTTN----STCTSGAGSLLLEFGVLSKLLGDDT 188

                   YekkarkardaLwklrcekpeGLypnyinpqtGqqwtqshislGAggDGS
                   Ye++ar+++++Lw+lr ++++GL++n i++qtG +w ++  +lGAg+D S
    C47E12.3   189 YERLARRVNEKLWNLR-NEVTGLHGNLIDIQTG-EWLGHLAGLGAGID-S 235

                   fYEYLlKayiltgktdleakdmyneAieAikkhlrrqskpsgLtyfaelk
                   fYEY+lK+yil+g++++  +dmyne++++i +++rr+++    + +++l+
    C47E12.3   236 FYEYMLKSYILFGNQRD--LDMYNESFARITTYMRRGRS----R-CSSLE 278

                   ngrfkilehkmdHLaCFdGGlfalgadsldaffpgEvlqvlegdkeiait
                   ++      +++++++ +dG+++++++dsl+a+f g   +vl+g++++a +
    C47E12.3   279 GDI-----PIYVNVDSRDGSTSNTWIDSLQASFAG--VLVLAGEVDEAVC 321

                   cHemYdrtwtklGpepfrFneaveksdqlslyeaaavkvlellafypLRP
                   +H+ Y+++w+k+G +p+rFn++++           a++v+    fypLRP
    C47E12.3   322 HHALYYAIWKKYGVLPERFNWQLQ-----------APDVS----FYPLRP 356

                   EviEStyyLYRNIaTkdpkmPTTNEYrewgweavqalekycRvkcGggls
                   E++ESty+LY   aTk+p+      Y+++g e++++le  +RvkcG
    C47E12.3   357 EFVESTYLLYT--ATKNPF------YQHVGLEILDSLETITRVKCG---- 394

                   sRyaglrnVytksigskeDrMESFfLAETlKYLYLlFdddnalqvellpl
                     +a++++V+++s+   eDrMESFfL+ETlKYLYLlFd d+  ++++ ++
    C47E12.3   395 --FATVHDVIDGSL---EDRMESFFLSETLKYLYLLFDVDH--PINKEQQ 437

                   dkctdevngnwVFNTEAHPlpi<-*
                   ++        + F+TE+H++pi
    C47E12.3   438 ES--------VLFSTEGHIFPI    451

DUF567: domain 1 of 1, from 510 to 525: score 4.9, E = 3.5
                   *->VkpevDyafiiaLvvv<-*
                      V  + D++f ++Lv++
    C47E12.3   510    VLHDCDGRFLMGLVLI    525



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