Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/C48D1.2
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: C48D1.2 CE29088 locus:ced-3 Caspase recruitment domain, ICE-like protease (caspase) p20 domain., ICE-like protease (caspase) p10 domai
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
ICE_p20 ICE-like protease (caspase) p20 domain 276.4 1.1e-82 1
ICE_p10 ICE-like protease (caspase) p10 domain 198.8 8.6e-56 1
CARD Caspase recruitment domain 119.9 5.8e-33 1
YfbU YfbU domain 6.1 2.4 2
Sua5_yciO_yrdC yrdC domain 4.7 4.4 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
YfbU 1/2 20 32 .. 177 189 .] 4.2 7.9
CARD 1/1 3 91 .. 1 90 [] 119.9 5.8e-33
YfbU 2/2 330 340 .. 179 189 .] 2.1 28
ICE_p20 1/1 241 365 .. 1 141 [] 276.4 1.1e-82
Sua5_yciO_yrdC 1/1 369 383 .. 177 191 .] 4.7 4.4
ICE_p10 1/1 405 496 .. 1 95 [] 198.8 8.6e-56
Alignments of top-scoring domains:
YfbU: domain 1 of 2, from 20 to 32: score 4.2, E = 7.9
*->HLSteEIrdILNA<-*
HL+ EI+ +L A
C48D1.2 20 HLKVDEILEVLIA 32
CARD: domain 1 of 1, from 3 to 91: score 119.9, E = 5.8e-33
*->aeddrrllrknrlellgeltlsglLdhLleknvLteeeeEkikaknt
++d+r+ll++n+++++++l+++++L++L++k+vL++++ ++i+++ t
C48D1.2 3 RQDRRSLLERNIMMFSSHLKVDEILEVLIAKQVLNSDNGDMINSCGT 49
trrdkareLiDsvqkkGnqAfqiFlqaLretdqelladlllde<-*
r k+re +++vq++G++Af++F++aLr+t++e+la++l+++
C48D1.2 50 VR-EKRREIVKAVQRRGDVAFDAFYDALRSTGHEGLAEVLEPL 91
YfbU: domain 2 of 2, from 330 to 340: score 2.1, E = 28
*->SteEIrdILNA<-*
St EI d LNA
C48D1.2 330 STHEIYDLLNA 340
ICE_p20: domain 1 of 1, from 241 to 365: score 276.4, E = 1.1e-82
*->rrGlaLIINNenFdketgLptRnGtdvDaenLtrlFrsLGYeVkvkn
+rG++LIINNe+F++ +ptRnGt++D++nLt+lFr++GY+V++k+
C48D1.2 241 PRGMCLIINNEHFEQ---MPTRNGTKADKDNLTNLFRCMGYTVICKD 284
DLTAeeMvlklrefAkredHkdsDSfvlVlLSHGeeahLqfPggIyGtdg
+LT+++M+l++r+fAk+e+H+ds+ +lV+LSHGee ++I+G+d+
C48D1.2 285 NLTGRGMLLTIRDFAKHESHGDSA--ILVILSHGEE------NVIIGVDD 326
kekvpDilslkkifnlFngdnCpSLkgKPKlfiIQACRGeelDv<-*
+ ++s+++i++l+n++n+p+L++KPK++++QACRGe++D+
C48D1.2 327 I-----PISTHEIYDLLNAANAPRLANKPKIVFVQACRGERRDN 365
Sua5_yciO_yrdC: domain 1 of 1, from 369 to 383: score 4.7, E = 4.4
*->VvdltddtpvvlRrG<-*
V d +d+ p++lRrG
C48D1.2 369 VLDSVDGVPAFLRRG 383
ICE_p10: domain 1 of 1, from 405 to 496: score 198.8, E = 8.6e-56
*->avyKiPveaDflafYSttpgyvSWRnskrGSwFIqaLcevlseyAkd
+++K+P++aD+l++Y+tt++yvSWRns+rGSwFIqa+cev+s++Akd
C48D1.2 405 VWRKKPSQADILIAYATTAQYVSWRNSARGSWFIQAVCEVFSTHAKD 451
levmeiLtkVnkkvareregfckdqpfnrkKqipcerstLtkklYlFP<-
++v+e+Lt+Vnkkva +gf+++q+ n++Kq+p+++s+L+kk+Y++P
C48D1.2 452 MDVVELLTEVNKKVA---CGFQTSQGSNILKQMPEMTSRLLKKFYFWP 496
*
C48D1.2 - -