Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/C48D5.2a
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Query: C48D5.2a CE17578 locus:ptp-1 protein tyrosine phosphatase (non receptor type) and band 4.1-like domain status:Partially_confirmed SW:P2
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
Band_41 FERM domain (Band 4.1 family) 445.7 1.2e-142 1
Y_phosphatase Protein-tyrosine phosphatase 385.9 4e-112 1
PDZ PDZ domain (Also known as DHR or GLGF) 102.3 1e-27 1
DSPc Dual specificity phosphatase, catalytic 4.4 5.9 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
Band_41 1/1 31 226 .. 1 210 [] 445.7 1.2e-142
PDZ 1/1 615 705 .. 1 84 [] 102.3 1e-27
DSPc 1/1 947 964 .. 108 125 .. 4.4 5.9
Y_phosphatase 1/1 777 1010 .. 1 274 [] 385.9 4e-112
Alignments of top-scoring domains:
Band_41: domain 1 of 1, from 31 to 226: score 445.7, E = 1.2e-142
*->ctvtllDstveeFkveKkdkGqvLLdkVfkhLglrEkdYFGLQylDd
ctvt+lDst+++F++eK+++G+vLL+kVf++L+++EkdYFGL+++++
C48D5.2a 31 CTVTFLDSTSYHFEIEKNSLGIVLLEKVFNYLEIIEKDYFGLVFIAV 77
DnsskdsptWLdpsKkirkQdvkkeePytLhFRvKFYpeDvpneLrqeiT
Dnss+++++WLdpsK++rkQ ++++Py+L+FRvKFY++D pn+Lr+e+T
C48D5.2a 78 DNSSAQQKKWLDPSKNLRKQ--MICPPYHLFFRVKFYVRD-PNRLRDEFT 124
rylffLQvkqdIleGrlpCpfetAvLLASYaVQsefGDYneslHkaGRtC
r++f++Qv+q+++eGrlpC++++++LLASY+VQ+e+GD++e++H+++RtC
C48D5.2a 125 RFQFYQQVRQNLEEGRLPCNEGSLALLASYVVQAEVGDFEEKTHGMSRTC 174
LCYLsdekllPqRVlnqkqltkddfEekIaelHkeHrGmspdeAeleYLk
LCY++++++lP ddf++++aelH++H+G++pd+Ae+++L+
C48D5.2a 175 LCYKIQFATLP-----------DDFSDRVAELHQLHIGQTPDVAEQNFLD 213
iArdLemYGVdff<-*
+Ar+LemYG+d++
C48D5.2a 214 HARRLEMYGMDVY 226
PDZ: domain 1 of 1, from 615 to 705: score 102.3, E = 1e-27
*->evtleke.vkrgglGfsikggsdk..givvsevlpGsgaAeagGrLk
vt++++++ +g++Gf++kgg d++ +++vs+v pGs+a+++++rL+
C48D5.2a 615 VVTIKMRpDRHGRFGFNVKGGADQnyPVIVSRVAPGSSADKCQPRLN 661
eGDvIlsvNGqdvenmsheravlaikgsgg....sevtLtvlRd<-*
eGD++l ++G+dv+ msh+ +v++i++++++ +++e++Lt++++
C48D5.2a 662 EGDQVLFIDGRDVSTMSHDHVVQFIRSARSglngGELHLTIRPN 705
DSPc: domain 1 of 1, from 947 to 964: score 4.4, E = 5.9
*->kVLVHCqAGiSRSAtlii<-*
++ VHC AGi R++ li+
C48D5.2a 947 PIVVHCSAGIGRTGVLIL 964
Y_phosphatase: domain 1 of 1, from 777 to 1010: score 385.9, E = 4e-112
*->NkeKNRykdilpyDhtRVkLk..egsDYINAnyidgpq.srtlvvyk
N+ KNRy+d+ pyD+tRV L+ ++++DYINAny++++++s+ +
C48D5.2a 777 NLAKNRYRDVCPYDDTRVTLQasPSGDYINANYVNMEIpSS-----G 818
kpkayIaTQgPlpnTieDFWrMvweqkvtvIVMLtklvEkgreeeKtCaq
++yIa+QgPl +T DFW Mvweq++t+IVMLt++ E+gr +K C+q
C48D5.2a 819 IVNRYIACQGPLAHTSSDFWVMVWEQHCTTIVMLTTITERGR--VK-CHQ 865
YWPeeggeeggsltyGditVtlvseekkddddytvRtleltn.gdeskne
YWP ++++++yG++ +++++ ++ ++++++R++ +++++
C48D5.2a 866 YWPR----VFETQEYGRLMIKCIKDKQ--TTNCCYREFSIRDrNS----- 904
akqeklkgetrtVthyhytgWPDhgvPesgpkslldflrkvrksqsqene
+e+r+Vt+++y +WPDhgvP++ pk++++f+++vrk++++ +
C48D5.2a 905 -------SEERRVTQMQYIAWPDHGVPDD-PKHFIQFVDEVRKARQGSVD 946
sgeaspdsgprSsctgPivVHCSAGiGRTGtfiaidillqqleaegvvid
PivVHCSAGiGRTG++i+++++++++e ++ v
C48D5.2a 947 ----------------PIVVHCSAGIGRTGVLILMETAACLVESNEPV-Y 979
ifdivkelRsqRpgmVQteeQYiFiydaile<-*
+div+++R+qR++++Qt+ QY F+++ il
C48D5.2a 980 PLDIVRTMRDQRAMLIQTPGQYTFVCESILR 1010