Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/C50F4.2
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: C50F4.2 CE05467 6-phosphofructokinase status:Partially_confirmed SW:Q27483 protein_id:CAA94737.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
PFK Phosphofructokinase 572.3 4.6e-209 2
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
PFK 1/2 13 319 .. 1 312 [] 476.4 5.7e-174
PFK 2/2 417 692 .. 14 312 .] 94.3 3.8e-34
Alignments of top-scoring domains:
PFK: domain 1 of 2, from 13 to 319: score 476.4, E = 5.7e-174
*->KkIgVLTSGGDApGMNAAiRAVVRsAiaeGleVygIyeGYaGLvaGG
gVLTSGGD++GMNAA+R+VVR i +G + y+I+eGY GL++G
C50F4.2 13 --VGVLTSGGDSQGMNAAVRSVVRETIRQGHRCYLIREGYNGLING- 56
dnIkqlewesVsdiiqrGGTilgSARcpEFrerEGRlkAaenLkkhGIda
nI+ + w+ V+++ ++GG +g+ Rc EFr+ GR+kAa++ ++ I
C50F4.2 57 -NIELAKWAHVANVTHLGGSMIGTSRCDEFRTTDGRKKAAAIMFDKRIFH 105
LVVIGGDGSytGAdlLteehgsLleeLvkeGkiteeevakyqylnivGlp
L+VIGGDGS++GA++L ee+g eeL +eGkitee ++ l G +
C50F4.2 106 LIVIGGDGSLMGAQKLKEEWGRFGEELFAEGKITEEVANEGRELHLAGIV 155
GTIDNDisGTDyTIGfdTAlntiveaIDrIrdTAsSHqRtFVVEVMGRhC
G+IDND +D IG dTAl++i+eaID + TA+SHqR+FVVEVMGRhC
C50F4.2 156 GSIDNDCIESDKSIGSDTALHRICEAIDGLVMTAQSHQRVFVVEVMGRHC 205
GdlALvaGiAgGADyIvIPEapApedfweeelanrlkrgrerGKrhnIvi
G+lAL a+iA ADy++ PE p p+++w+e+l+ +l r+ GKr n++i
C50F4.2 206 GYLALTAAIAVEADYVFYPEIP-PDEKWPEQLCHQLGSVRKMGKRQNVII 254
VAEgaidkqlkpitseavkklkvagLgldtRvTVLGHvQRGGtPtAfDRi
+ Eg++ ++ i+ +vk++ +++L+l++R+ +LGH QRGG P+ DR
C50F4.2 255 LGEGVTNSKGQRIDVRQVKEEIETRLQLEVRIATLGHLQRGGAPSFLDRL 304
LASrmGaeAVeaLLe<-*
+ rmG eAV+ +L
C50F4.2 305 IGLRMGYEAVQEVLK 319
PFK: domain 2 of 2, from 417 to 692: score 94.3, E = 3.8e-34
*->GMNAAiRAVVRsAiaeGleVygIyeGYaGLvaGGdnIkqlewesVsd
GMNAA + +R+A G+ V+gI +G GL + + k l+w+ V
C50F4.2 417 GMNAATYSFTRMANHSGIQVIGIKHGWDGLKNK--DVKLLTWANVQG 461
iiqrGGTilgSARcpEFrerEGRlkAaenLkkhGIdaLVVIGGDGSytGA
+ q GG lg+ R E l A e L + +d+LV+IGG + A
C50F4.2 462 WAQFGGSMLGTKRQ---LPSEMDLIA-EGLNSNNVDGLVIIGGFMAFESA 507
dlLteehgsLleeLvkeGkiteeevakyqylnivGlpGTIDNDisGTDyT
++L + + ++iv p TI N +GT +
C50F4.2 508 LILQQNRS----------------EYTCLSIPIVVIPATISNNCPGTCMS 541
IGfdTAlntiveaIDrIrdTAs.SHqRtFVVEVMGRhCGdlALvaGiAgG
G dTAln i+ +D I A +S + + ++E MG G+lA ++++++G
C50F4.2 542 LGVDTALNEICRQVDNISQNAIgSKNKVMIIETMGSRSGFLATMTALSTG 591
ADyIvIPEapApedfweeelanrlkrgrerGKrhnIviV.AEgaidkqlk
+ +I + ++++ e+la + k+ +G +++Ega d
C50F4.2 592 SQFALIRQVE-TNEKDLEKLAIETKERLDSGNLEKFLLIrSEGASD---- 636
pitseavkkl..kvagLgldtRvTVLGHvQRGGtPtAfDRiLASrmGaeA
i s +vkk+ +kv + ++ +R+T LG Q GG P+ fDR + rmG++A
C50F4.2 637 EIYSPDVKKIfdKVMKNKYGVRITNLGYSQLGGHPSCFDRQMGIRMGVRA 686
VeaLLe<-*
e +++
C50F4.2 687 FEGIVN 692