Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm2/seq/C50F7.4
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Query:  C50F7.4  CE04242   succinyl-CoA synthetase beta chain status:Partially_confirmed SW:P53589 protein_id:AAA83304.1

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N
--------   -----------                                  -----    ------- ---
ligase-CoA CoA-ligase                                   295.6      6e-85   1
ATP-grasp  ATP-grasp domain                             193.0    1.7e-55   1
Vps26      Vacuolar protein sorting-associated protei     4.5       0.97   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
Vps26        1/1     173   193 ..     1    21 [.     4.5     0.97
ATP-grasp    1/1      48   226 ..     1   190 []   193.0  1.7e-55
ligase-CoA   1/1     274   413 ..     1   152 [.   295.6    6e-85

Alignments of top-scoring domains:
Vps26: domain 1 of 1, from 173 to 193: score 4.5, E = 0.97
                   *->FGppidIeIkldngeeRKtVe<-*
                      F++pidI+  ++ g++ K+++
     C50F7.4   173    FKTPIDIQMGMTEGQSLKIAK    193

ATP-grasp: domain 1 of 1, from 48 to 226: score 193.0, E = 1.7e-55
                   *->eeaeenapalgvseaddsvvvkaqdlaggrgkaekcd.GlkfiGgvk
                       eaee ++++g+     ++vvkaq+laggrgk+ k+ +G+k+iGgv+
     C50F7.4    48    KEAEEKWMSFGD----HEYVVKAQILAGGRGKG-KFInGTKGIGGVF 89

                   ltfeieevkedalellgknLvtkqtgvkgqpvpkalvleadkikreyyla
                   +t+e++++ e+  e++gk+Lvtkqt+ +g+ v k++++e+++ikre yla
     C50F7.4    90 ITKEKDAALEAIDEMIGKRLVTKQTTSEGVRVDKVMIAEGVDIKRETYLA 139

                   kvldrptpgpvviasleGGveieevaeklgnfdfpavlKarrdgydGkgq
                    ++dr + gpvv+as++GG++ie+vaek++    ++++K+++d   G ++
     C50F7.4   140 VLMDRESNGPVVVASPDGGMDIEAVAEKTP----ERIFKTPIDIQMGMTE 185

                   yvareiakedglealkellvgaradlivelyvpFeeeeasllei<-*
                    +  +iak +++e+   +l+g +a+ i+ ly +F+ ++a+++ei
     C50F7.4   186 GQSLKIAKDLQFEG---KLIGVAAQEIKRLYDLFIAVDATQVEI    226

ligase-CoA: domain 1 of 1, from 274 to 413: score 295.6, E = 6e-85
                   *->akynLnPsyIgldGnIGcvVNGAGLAMATmdiIklnGggPAnfLDvG
                      +++nLn  yIg+dGnI+c+VNGAGLAMATmd+Ikl+Gg+PAnfLDvG
     C50F7.4   274    HQFNLN--YIGMDGNIACLVNGAGLAMATMDLIKLHGGEPANFLDVG 318

                   GdatpgttvtdafklilsDpnVkaIlvnIFgGIvrCdeiAdGlkeaarev
                   G++t+++ v++a+++i+sDp+Vk++l+nIFgGIv+C++iA+G+++a++++
     C50F7.4   319 GAVTEDA-VFNAVRIITSDPRVKCVLINIFGGIVNCATIANGVVSAVNKI 367

                   klkvPlVvRLaGTnvdegkseRkghagSglnilsadaacKnaALreAavk
                   +l+vP+VvRL+GTnvd++k   +++++Sgl+il+a++      L+eAa+k
     C50F7.4   368 GLNVPMVVRLEGTNVDAAK---QIMKKSGLKILTANN------LDEAAAK 408

                   vVesp<-*
                   +V+s+
     C50F7.4   409 AVSSL    413



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