Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm2/seq/D2013.5
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Query:  D2013.5  CE00930   GTP-binding protein status:Partially_confirmed TR:Q18965 protein_id:CAA87771.1

Scores for sequence family classification (score includes all domains):
Model     Description                                   Score    E-value  N
--------  -----------                                   -----    ------- ---
dynamin   Dynamin family                                 66.8    4.6e-16   1
ras       Ras family                                      8.8       0.16   1
Adaptin_N Adaptin N terminal region                       5.0        1.3   1
OTCace_N  Aspartate/ornithine carbamoyltransferase, c     4.5        5.4   1
DUF135    Protein of unknown function  DUF135             2.9          9   1
dynamin_2 Dynamin central region                          2.8        6.8   1
Bcl-2     Apoptosis regulator proteins, Bcl-2 family      1.4        8.7   1

Parsed for domains:
Model     Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------  ------- ----- -----    ----- -----      -----  -------
Bcl-2       1/1     117   125 ..   100   108 .]     1.4      8.7
Adaptin_N   1/1     181   208 ..     1    32 [.     5.0      1.3
ras         1/1     289   304 ..     1    16 [.     8.8     0.16
dynamin     1/1     286   476 ..    24   213 .]    66.8  4.6e-16
DUF135      1/1     479   490 ..   367   378 .]     2.9        9
dynamin_2   1/1     481   501 ..     1    20 [.     2.8      6.8
OTCace_N    1/1     579   592 ..     1    14 [.     4.5      5.4

Alignments of top-scoring domains:
Bcl-2: domain 1 of 1, from 117 to 125: score 1.4, E = 8.7
                   *->eWiqenGGW<-*
                      eW  +nG+W
     D2013.5   117    EWFDSNGSW    125

Adaptin_N: domain 1 of 1, from 181 to 208: score 5.0, E = 1.3
                   *->ekkeitqelaeilnsfkddKkLdpykkkdavk<-*
                      ++  i+  l+ +++s kd+    p++kkd+v+
     D2013.5   181    KEPVILASLMSAFSSKKDE----PEEKKDNVS    208

ras: domain 1 of 1, from 289 to 304: score 8.8, E = 0.16
                   *->KlVliGDsGVGKSsLl<-*
                       +V++GD + GK+s l
     D2013.5   289    RVVVVGDQSAGKTSVL    304

dynamin: domain 1 of 1, from 286 to 476: score 66.8, E = 4.6e-16
                   *->dLPqIAVvGgQSaGKSSVLEnlvGkdfLPRGsG.IVTRrPLvLkLik
                      +LP + VvG+QSaGK SVLE        PRGsG+  TR P    L +
     D2013.5   286    NLPRVVVVGDQSAGKTSVLEMVAQARIFPRGSGeMMTRAPVKVTLSE 332

                   lvte.teyaeflhykgkeikfsdfseVrkeIedetdrVtGtnkgISpelI
                   ++    ++++     +  +k +d +  r+e e         +k +S+e I
     D2013.5   333 GPYHvAQFRDSSREFDL-TKETDLQQLRNETEVRMRNSVRDGKTVSNEVI 381

                   nLrvySphVlnLTLIDLPGltkVavgdQPaDIeqqIkdlikkfIskeecl
                   +L v  p+ + + L+DLPG+      d        I  + k   +  + +
     D2013.5   382 SLTVKGPNLPRMVLVDLPGVISTVTADMARETKDDIIRMSKAHMENPNAI 431

                   iLaVvPaNvDlAtsdALklAkEVDPqGeRTiGvlTKlDLvDeGTd<-*
                   iL +    vD   s+   l   +DP G+RTi vlTK D+  +
     D2013.5   432 ILCIQDGSVDAERSNVTDLVSSIDPSGKRTILVLTKVDMAEKNLA    476

DUF135: domain 1 of 1, from 479 to 490: score 2.9, E = 9
                   *->drIrelLkGglw<-*
                      drI  +L G+l+
     D2013.5   479    DRIKKILEGKLF    490

dynamin_2: domain 1 of 1, from 481 to 501: score 2.8, E = 6.8
                   *->avDiLrNrViPLk.kGYmgVv<-*
                      + +iL+++++P k +GY gVv
     D2013.5   481    IKKILEGKLFPMKaLGYFGVV    501

OTCace_N: domain 1 of 1, from 579 to 592: score 4.5, E = 5.4
                   *->RHLLsikdlsreEl<-*
                       H+L+i +l+r+El
     D2013.5   579    NHFLRIRQLNRDEL    592



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