Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/E03G2.2
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Query: E03G2.2 CE03119 locus:mrp-3 multidrug resistance-associated protein status:Partially_confirmed TR:Q19048 protein_id:CAA92148.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
ABC_tran ABC transporter 214.0 8e-61 2
ABC_membrane ABC transporter transmembrane region 181.1 1.8e-50 2
DUF446 Domain of unknown function, DUF445 7.9 0.35 1
FBPase_glpX Bacterial fructose-1,6-bisphosphatase, 5.5 0.75 1
Sua5_yciO_yrdC yrdC domain 5.2 3.1 1
Coq4 Coenzyme Q (ubiquinone) biosynthesis p 4.3 3.1 1
PRK Phosphoribulokinase / Uridine kinase f 3.2 6.6 1
Sec15 Exocyst complex subunit Sec15-like 2.8 9.6 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
ABC_membrane 1/2 236 507 .. 1 285 [] 93.6 3.9e-24
DUF446 1/1 597 610 .. 91 104 .] 7.9 0.35
Sec15 1/1 646 658 .. 1 13 [. 2.8 9.6
ABC_tran 1/2 581 754 .. 1 199 [] 76.3 6.1e-21
Sua5_yciO_yrdC 1/1 740 755 .. 1 16 [. 5.2 3.1
ABC_membrane 2/2 835 1113 .. 1 285 [] 95.4 1.1e-24
PRK 1/1 1188 1205 .. 1 19 [. 3.2 6.6
FBPase_glpX 1/1 1198 1212 .. 1 15 [. 5.5 0.75
Coq4 1/1 1228 1239 .. 209 220 .] 4.3 3.1
ABC_tran 2/2 1185 1368 .. 1 199 [] 140.0 2.3e-39
Alignments of top-scoring domains:
ABC_membrane: domain 1 of 2, from 236 to 507: score 93.6, E = 3.9e-24
*->lliailllilagatalvtfplllgrlldsgfplsdgnddharsslis
+l + + ++l++++ ++ p +l++l+ + + n + ++i
E03G2.2 236 ILGGSFIKFLSDLLQFA-NPTFLNYLILF---IETPNAP--LINGIG 276
lailslfavfvliglllqgsfyllagerlgqrlrkrlfrallrqilglfd
la++ lf+++ + +l+ +++f+ + r+g ++ ++l a++++ l l+
E03G2.2 277 LAVG-LFLAGQIKSLFMNTYFIA--MTRVGAKIQTMLSCAVYEKSLLLSN 323
sffdtnsvGeltsRltnDvekirdglgeklgllfqslatvvgglivmfyy
++ +++vGe ++ l+ Dv++ r +++ ++ ++++++++++++ ++
E03G2.2 324 TARRERTVGEMVNILSIDVDRFRMITPQIQQYWSSPFQIIICMVLLSQTI 373
swkLtLillailpllillsavlakklrklsrkeqkayakagsvaeEslsg
++ + +++ ++ +++++ +++++++ + + +k +++ ++++E+l+g
E03G2.2 374 GVAVWAGIV-VMISIVPINICVSMITKRWQLRLMKYKDERIRLINEVLNG 422
irTVkafgrEeyelerfdkaledaekagikkaiiagllfgitqlisylsy
i++Vk ++E +++e ++ +++ k + a++ ++ + + ++ ++
E03G2.2 423 IKVVKLSAWETAMEETIERVRDKELKMIKQSALLKTFADCLNVGAPVFVA 472
alalwfGgylvasvisgglsvgtlfaflslgnqligpl<-*
+ +++++ +++l++ + f++lsl+n+l+gpl
E03G2.2 473 LSSFTVFVLI---DPKNVLTPNIAFVSLSLFNLLRGPL 507
DUF446: domain 1 of 1, from 597 to 610: score 7.9, E = 0.35
*->alLApLeelDkLiq<-*
+lLA+L+e++k+++
E03G2.2 597 LLLAALGEMEKVCG 610
Sec15: domain 1 of 1, from 646 to 658: score 2.8, E = 9.6
*->eYekvilkCWmKE<-*
+Y+kvi++C +KE
E03G2.2 646 LYKKVIESCALKE 658
ABC_tran: domain 1 of 2, from 581 to 754: score 76.3, E = 6.1e-21
*->GevlalvGpNGaGKSTLLklisGllppteGtilldGardlsdlsklk
e++ +vG+ G+GKS+LL + +G+ + G + + G
E03G2.2 581 KELVTVVGSVGSGKSSLLLAALGEMEKVCGYVGVRG-S--------- 617
erlerlrknigvvfQdptlfpnpeltvreniafglrlslglskdeqrdrl
+++++Q+p ++ + ++ n+++ + l ++ ++++
E03G2.2 618 ---------VAYLSQQPWIL---NQSLKKNVLMQADL----NDVLYKKVI 651
kkagaeelLerlglgydhlldrrpgtLSGGqkQRvaiARaLltkpklLlL
+ + + e L++l+ g+d+ +++++ +LSGGqk R+a+ARa+++ ++++L
E03G2.2 652 ESCALKEDLKQLPDGDDTEIGEKGINLSGGQKARIALARAVYQSKDVYFL 701
DEPTagLDpasraqllellrelrqq..ggTvllitHdldlldrlaDrilv
D P ++ D++ +++++ + + + +T +l+t + ++ + +i+v
E03G2.2 702 DDPLSAVDAHVGKHIFDNVIGPNGMlsHTTRILVTNCTSF-LQESGKIIV 750
ledG<-*
++
E03G2.2 751 MKGE 754
Sua5_yciO_yrdC: domain 1 of 1, from 740 to 755: score 5.2, E = 3.1
*->aallkgGeIVAypTdt<-*
+ l+++G+I++++++t
E03G2.2 740 SFLQESGKIIVMKGET 755
ABC_membrane: domain 2 of 2, from 835 to 1113: score 95.4, E = 1.1e-24
*->lliailllilagatalvtfplllgrlldsgfplsdgnddharsslis
++ + l ++a+++++ f+l +++l +sd+n+d ++
E03G2.2 835 IVTYVLPYAIAVVLNVS-FALGRSLWLTA---WSDANID--INHPDT 875
lails..lfavfvliglllqgsfyllagerlgqrlrkrlfrallrqilgl
++++ + +++++++i+ +++ +f l+ + + g ++k l++ ll+ +l+
E03G2.2 876 MSVGArlGVYAGFGITEVIFLFFSLVLLLIGGVAASKNLHKPLLHNVLRN 925
fdsffdtnsvGeltsRltnDvekirdglgeklgllfqslatvvgglivmf
+ s+fd ++ G++++Rl++D+e ++ l+ ++ +l+++l+++ ++++ +
E03G2.2 926 PLSYFDITPIGRIINRLAKDMEVVDLRLSSSFRFLVMALINMTVLIV--S 973
yyswkLtLillailpllillsavlakklrklsrkeqkayakagsvaeEsl
y + + i+++++ +++++ ++ k +r+l+r + +++++s + E+l
E03G2.2 974 YTTPLFIAIIIPVFIIYFFVLKYSIKSTRQLQRIASLTRSPIFSNFSETL 1023
sgirTVkafgrEeyelerfdkaledaekagikkaiiagllfgitqlisyl
gi TV+af + + +++r d+ l+++ k ++ + ++++l+++++l++++
E03G2.2 1024 QGISTVRAFQWSDEFVRRNDEHLNTHVKCSYYSQMANRWLSIRLELLGNI 1073
syalalwfGgylvasvisgglsvgtlfaflslgnqligpl<-*
+++ a+ ++ + s+i+ g+ ++++ ++l+++ +l++ +
E03G2.2 1074 VIFSAAILAIIGKESGITAGMLGLSVSYSLNITFMLNMFV 1113
PRK: domain 1 of 1, from 1188 to 1205: score 3.2, E = 6.6
*->vIGvaGsSGaGKTtvarri<-*
Gv+G GaGK++ a ++
E03G2.2 1188 -VGVCGRTGAGKSSLALAL 1205
FBPase_glpX: domain 1 of 1, from 1198 to 1212: score 5.5, E = 0.75
*->drsLAmElvRVTEaA<-*
+sLA+ l+R +EaA
E03G2.2 1198 KSSLALALFRIVEAA 1212
Coq4: domain 1 of 1, from 1228 to 1239: score 4.3, E = 3.1
*->leelRkeLgIta<-*
l++lR++L I++
E03G2.2 1228 LHDLREKLTIIP 1239
ABC_tran: domain 2 of 2, from 1185 to 1368: score 140.0, E = 2.3e-39
*->GevlalvGpNGaGKSTLLklisGllppteGtilldGardlsdlsklk
G+++++ G++GaGKS+L+ ++ ++ + + G i++d s+++
E03G2.2 1185 GQKVGVCGRTGAGKSSLALALFRIVEAADGNISIDQ-TITSHIG--- 1227
erlerlrknigvvfQdptlfpnpeltvreniafglrlslglskdeqrdrl
l++lr+++ ++Q+ +lf +t+r ni+ ++ +++ ++ +l
E03G2.2 1228 --LHDLREKLTIIPQENVLF---ANTLRFNIDPKGQF----TDQQLWLAL 1268
kkagaeelLerlglgydhlldrrpgtLSGGqkQRvaiARaLltkpklLlL
+++++ + +e l+ + ++ + + + ++S Gq+Q +++ RaLl+k+k+L+L
E03G2.2 1269 ENSNLKAHVELLPHKLESPVAEGGENFSVGQRQLLCLTRALLRKSKVLVL 1318
DEPTagLDpasraqllellrelrqqggTvllitHdldlldrlaDrilvle
DE+Tag+D + +++++re + T+++i H+l ++++ ri+v++
E03G2.2 1319 DEATAGIDNRTDTMVQATIREKFA-DSTIITIAHRLHTIIDYD-RIIVMD 1366
dG<-*
+G
E03G2.2 1367 AG 1368
[output cut off at A = 10 top alignments]