Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/F02A9.6
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: F02A9.6 CE00237 locus:glp-1 GLP-1 protein status:Partially_confirmed SW:P13508 protein_id:CAA79620.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
notch Notch (DSL) domain 224.2 1.9e-63 3
EGF EGF-like domain 170.0 3.8e-47 13
ank Ankyrin repeat 109.3 2.4e-29 6
HlyC RTX toxin acyltransferase family 3.7 4 1
DUF660 Family of unknown function (DUF660) 3.5 7.6 1
Alpha_adaptin_C Alpha adaptin AP2, C-terminal domain 2.9 3.7 1
MGAT2 N-acetylglucosaminyltransferase II (M -0.8 9.9 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
EGF 1/13 23 57 .. 1 45 [] 21.1 0.00029
EGF 2/13 101 110 .. 31 45 .] 2.6 50
EGF 3/13 121 151 .. 1 45 [] 22.2 0.00014
EGF 4/13 158 189 .. 1 45 [] 28.8 1.9e-06
EGF 5/13 194 229 .. 1 45 [] 22.6 0.00011
EGF 6/13 236 268 .. 1 45 [] 31.4 3.5e-07
EGF 7/13 275 307 .. 1 45 [] 19.0 0.0012
EGF 8/13 310 320 .. 30 45 .] 6.6 3.7
EGF 9/13 329 358 .. 1 45 [] 21.5 0.00023
EGF 10/13 373 405 .. 1 45 [] 35.3 2.8e-08
EGF 11/13 411 442 .. 1 45 [] 22.2 0.00014
MGAT2 1/1 444 450 .. 518 524 .] -0.8 9.9
EGF 12/13 450 478 .. 1 45 [] 27.8 3.9e-06
Alpha_adaptin_C 1/1 487 497 .. 98 108 .. 2.9 3.7
notch 1/3 489 527 .. 1 42 [] 79.3 7.7e-20
EGF 13/13 542 559 .. 1 17 [. -1.0 5.2e+02
notch 2/3 531 568 .. 1 42 [] 78.4 1.5e-19
notch 3/3 569 608 .. 1 42 [] 81.5 1.8e-20
ank 1/6 949 960 .. 22 33 .] 7.2 3.1
ank 2/6 961 993 .. 1 33 [] 22.2 0.00016
ank 3/6 994 1015 .. 1 22 [. 4.8 14
ank 4/6 1030 1065 .. 1 33 [] 21.6 0.00023
ank 5/6 1074 1106 .. 1 33 [] 32.4 1.9e-07
ank 6/6 1107 1139 .. 1 33 [] 25.6 1.7e-05
HlyC 1/1 1152 1161 .. 152 161 .] 3.7 4
DUF660 1/1 1184 1198 .. 212 226 .] 3.5 7.6
Alignments of top-scoring domains:
EGF: domain 1 of 13, from 23 to 57: score 21.1, E = 0.00029
*->CapnnpCsngGtCvntpggssdnfggytCeCppGdyylsytGkrC<-
C + Cs +G+C n+ ++y C+C+ G + G +C
F02A9.6 23 CGREGACSVNGKCYNGKL-----IETYWCRCKKG-----FGGAFC 57
*
F02A9.6 - -
EGF: domain 2 of 13, from 101 to 110: score 2.6, E = 50
*->CppGdyylsytGkrC<-*
C +G y G++C
F02A9.6 101 CEEG-----YGGPDC 110
EGF: domain 3 of 13, from 121 to 151: score 22.2, E = 0.00014
*->CapnnpCsngGtCvntpggssdnfggytCeCppGdyylsytGkrC<-
C+++ pC+n G C + g g++C+C +G y G +C
F02A9.6 121 CDSD-PCNN-GLCYPFYG-------GFQCICNNG-----YGGSYC 151
*
F02A9.6 - -
EGF: domain 4 of 13, from 158 to 189: score 28.8, E = 1.9e-06
*->CapnnpCsngGtCvntpggssdnfggytCeCppGdyylsytGkrC<-
Ca+n C +g tCvn+ y+C+Cp G +G++C
F02A9.6 158 CAQN-ECAEGSTCVNSVY-------NYYCDCPIG-----KSGRYC 189
*
F02A9.6 - -
EGF: domain 5 of 13, from 194 to 229: score 22.6, E = 0.00011
*->Capnn.pCsngGtCvntpggssdnfggytCeCppGdyylsytGkrC<
Ca+ + C++ G+C++ ++ + ++C+C G y G++C
F02A9.6 194 CALMGnICNH-GRCIPNRD----EDKNFRCVCDSG-----YEGEFC 229
-*
F02A9.6 - -
EGF: domain 6 of 13, from 236 to 268: score 31.4, E = 3.5e-07
*->CapnnpCsngGtCvntpggssdnfggytCeCppGdyylsytGkrC<-
C + C n+ tC n++g ++tC+C+pG y+Gk+C
F02A9.6 236 CLIEETCVNNSTCFNLHG-------DFTCTCKPG-----YAGKYC 268
*
F02A9.6 - -
EGF: domain 7 of 13, from 275 to 307: score 19.0, E = 0.0012
*->CapnnpCsngGtCvntpggssdnfggytCeCppGdyylsytGkrC<-
C + +C+n+G C + +++ C C +G +tG rC
F02A9.6 275 CKDY-VCQNDGYCAHDSN------QMPICYCEQG-----FTGQRC 307
*
F02A9.6 - -
EGF: domain 8 of 13, from 310 to 320: score 6.6, E = 3.7
*->eCppGdyylsytGkrC<-*
eCp G + G++C
F02A9.6 310 ECPSG-----FGGIHC 320
EGF: domain 9 of 13, from 329 to 358: score 21.5, E = 0.00023
*->Capnn.pCsngGtCvntpggssdnfggytCeCppGdyylsytGkrC<
C+ n+ C n+G+C+n+ +C+C p y+G+rC
F02A9.6 329 CSRSNgTCYNDGRCING-----------FCVCEPD-----YIGDRC 358
-*
F02A9.6 - -
EGF: domain 10 of 13, from 373 to 405: score 35.3, E = 2.8e-08
*->CapnnpCsngGtCvntpggssdnfggytCeCppGdyylsytGkrC<-
C n pC n++tC+++ + +gy+C+Cp G + G +C
F02A9.6 373 CKYN-PCVNNATCIDLKN------SGYSCHCPLG-----FYGLNC 405
*
F02A9.6 - -
[output cut off at A = 10 top alignments]