Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm2/seq/F09B9.2b
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Query:  F09B9.2b  CE02176  locus:unc-115 LIM domains status:Confirmed TR:Q95QM5 protein_id:CAC70079.1

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
LIM      LIM domain                                     102.4    1.4e-27   3
VHP      Villin headpiece domain                         75.8    1.8e-23   2
IATP     Mitochondrial ATPase inhibitor, IATP             5.5        6.6   1
DC1      DC1 domain                                       5.2          3   2
Xlink    Extracellular link domain                        2.2        2.2   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
DC1        1/2      17    28 ..     1    12 [.     4.5      5.3
LIM        1/3      19    58 ..     1    43 [.    36.9  5.3e-09
DC1        2/2      43    59 ..     1    20 [.     3.3       12
VHP        1/2      65    74 ..     1    10 [.     0.7  1.2e+02
Xlink      1/1     151   156 ..    99   104 .]     2.2      2.2
LIM        2/3     131   187 ..     1    62 []    57.0  1.1e-14
LIM        3/3     190   236 ..     1    51 [.    25.1  1.2e-05
IATP       1/1     540   564 ..     1    27 [.     5.5      6.6
VHP        2/2     604   639 .]     1    36 []    72.4  2.5e-22

Alignments of top-scoring domains:
DC1: domain 1 of 2, from 17 to 28: score 4.5, E = 5.3
                   *->fsCdvCerkidp<-*
                      ++CdvC++k+++
    F09B9.2b    17    KKCDVCRKKCSG    28

LIM: domain 1 of 3, from 19 to 58: score 36.9, E = 5.3e-09
                   *->CagCnkpIydrevvrralnkvwHpeCFrCavCgkpLtegdefy<-*
                      C  C k++ + ++   a++k++H++CF+C  Cg++L+e++ fy
    F09B9.2b    19    CDVCRKKCSGDVLK--ANDKYFHINCFQCKKCGRNLGETG-FY    58

DC1: domain 2 of 2, from 43 to 59: score 3.3, E = 12
                   *->fsCdvCerkidpgsngffYs<-*
                      f C  C+r++ +    +fY+
    F09B9.2b    43    FQCKKCGRNLGE---TGFYT    59

VHP: domain 1 of 2, from 65 to 74: score 0.7, E = 1.2e+02
                   *->YLsdeDFeev<-*
                      YL ++DF+ v
    F09B9.2b    65    YLCPDDFRAV    74

Xlink: domain 1 of 1, from 151 to 156: score 2.2, E = 2.2
                   *->YDvYCF<-*
                      ++vYCF
    F09B9.2b   151    WHVYCF    156

LIM: domain 2 of 3, from 131 to 187: score 57.0, E = 1.1e-14
                   *->CagCnkpIydrevvrralnkvwHpeCFrCavCgkpLtegdefyekdg
                      Ca+C++  ++ +v+  al+ +wH+ CF+C++C   L     ++++ g
    F09B9.2b   131    CAACDQALHSGQVLL-ALGLSWHVYCFKCSECSAVLHGE--YMSHHG 174

                   skelYCkhDyyklfg<-*
                    k ++C +Dy ++fg
    F09B9.2b   175 -K-PLCLRDYNEKFG    187

LIM: domain 3 of 3, from 190 to 236: score 25.1, E = 1.2e-05
                   *->CagCnkpIydrevvrralnkvwHpeCFrCavCgkpLtegdefyekdg
                      C+ C k I++ ++   a++  +Hp C rC+ Cg ++++g e y+  +
    F09B9.2b   190    CYECEKFIAGKVLQ--AGGYKFHPTCARCSRCGSHFGDGEEMYMQGD 234

                   skel<-*
                    + +
    F09B9.2b   235 -E-I    236

IATP: domain 1 of 1, from 540 to 564: score 5.5, E = 6.6
                   *->msarGfgSdggegvggggGSiReAGGa<-*
                      +s+  ++S+ +++  g +G +R+AGGa
    F09B9.2b   540    ISS--HYSEHSTTESGTAGGPRSAGGA    564

VHP: domain 2 of 2, from 604 to 639: score 72.4, E = 2.5e-22
                   *->YLsdeDFeevFgMtkeEFykLPlWKqnqLKKklgLF<-*
                      +L++++Fee+F+M+  EFykLP+WK+ +LK+k++LF
    F09B9.2b   604    HLPRDQFEEIFKMSLIEFYKLPEWKRINLKRKHKLF    639



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