Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/F09E5.1
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Query: F09E5.1 CE02604 locus:pkc-3 Protein kinase C status:Confirmed TR:Q19266 protein_id:AAA79341.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
pkinase Protein kinase domain 254.5 1.5e-72 1
pkinase_C Protein kinase C terminal domain 97.7 7.5e-29 1
PB1 PB1 domain 81.5 1.3e-21 1
DAG_PE-bind Phorbol esters/diacylglycerol binding 42.1 1.7e-09 1
Herpes_DNAp_acc Herpes DNA replication accessory fact 5.8 0.81 1
Myelin_PLP Myelin proteolipid protein (PLP or li 2.7 5 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
Myelin_PLP 1/1 38 53 .. 273 288 .] 2.7 5
PB1 1/1 12 95 .. 1 85 [] 81.5 1.3e-21
Herpes_DNAp_acc 1/1 153 176 .. 1 24 [. 5.8 0.81
DAG_PE-bind 1/1 128 177 .. 1 51 [] 42.1 1.7e-09
pkinase 1/1 253 522 .. 1 294 [] 254.5 1.5e-72
pkinase_C 1/1 526 590 .. 1 70 [] 97.7 7.5e-29
Alignments of top-scoring domains:
Myelin_PLP: domain 1 of 1, from 38 to 53: score 2.7, E = 5
*->yAVLKflgRkdkytkf<-*
+A LK+++++ k +++
F09E5.1 38 FALLKDACKQHKKQDI 53
PB1: domain 1 of 1, from 12 to 95: score 81.5, E = 1.3e-21
*->tvdvKlrYgggirrilsvsrdisfeeLrskvakrfgl....tfklkY
++++K r++g ++ l+ ++++ ++++ +++++ ++++++++++ k+
F09E5.1 12 DIKLKTRFQGQVVV-LYARPPLILDDFFALLKDACKQhkkqDITVKW 57
pDeDgDdlVsissDeDLeeaieeyrsllsegsktlrlfvfpa<-*
+DeDg d++si s+++L+ea+++++s+ + +l+++vf+
F09E5.1 58 IDEDG-DPISIDSQMELDEAVRCLNSS---QEAELNIHVFVG 95
Herpes_DNAp_acc: domain 1 of 1, from 153 to 176: score 5.8, E = 0.81
*->tyslrlkveaLaqlsKiYdHiKsh<-*
+++r + ++L+++ K++ H+ +h
F09E5.1 153 RQGFRCVDCRLCVHKKCHRHVRTH 176
DAG_PE-bind: domain 1 of 1, from 128 to 177: score 42.1, E = 1.7e-09
*->HrFkrttfyksptfCdhCgellwglakQGlkCsnCglnvHkrChekV
HrF+++++ ++ C C + +wg+++QG++C +C+l vHk+Ch+ V
F09E5.1 128 HRFQAKRL-NRRIQCFICHDYIWGIGRQGFRCVDCRLCVHKKCHRHV 173
ptnC<-*
t C
F09E5.1 174 RTHC 177
pkinase: domain 1 of 1, from 253 to 522: score 254.5, E = 1.5e-72
*->yelleklGeGsfGkVykakhkdktgkiVAvKilkk....ekesikek
++ll ++G+Gs++kV +a+h+ +t +i+A+Ki+kk+ +e+e+i++
F09E5.1 253 FRLLTVIGRGSYAKVVQAEHV-STRQIYAIKIIKKemfnEDEDIDW- 297
rflrEiqilkrLs.HpNIvrligvfedtddhlylvmEymegGdLfdylrr
+++E ++ s+ p++v l+ f+ t+++l +v E+++gGdL+ ++++
F09E5.1 298 -VQTEKSVFEAASnYPFLVGLHSCFQ-TESRLFFVIEFVPGGDLMFHMQQ 345
nggplsekeakkialQilrGleYLHsngivHRDLKpeNILldendgtvKi
++ +l+e++a+++ +i +l +LHs+gi++RDLK +N+L+d + g++K+
F09E5.1 346 QR-KLPEEHARFYSGEIILALHFLHSRGIIYRDLKLDNVLIDAE-GHIKL 393
aDFGLArlle.sssklttfvGTpwYmmAPEvilegrgysskvDvWSlGvi
+D G++++ +++ ++tf+GTp+Y+ APE+ l+g++y+ vD+W+lGv+
F09E5.1 394 TDYGMCKENIkDGDLTSTFCGTPNYI-APEI-LRGDEYGFSVDWWALGVL 441
LyElltggplfpgadlpaftggdevdqliifvlklPfsdelpktridple
++E++ g ++Pf+ + ++++++e
F09E5.1 442 MFEMMAG--------------------------RSPFDIVGMQNSEENTE 465
elfriikrpglrlplpsncSeelkdLlkkcLnkDPskRpG.....satak
++ i + +++p+++S + +lk+ LnkDP++R+G + + + +
F09E5.1 466 DYLFQIIL-ERQIRIPRSLSVRASGILKGFLNKDPTERLGckldiNEGLR 514
eilnhpwf<-*
++++h +f
F09E5.1 515 DMKEHQFF 522
pkinase_C: domain 1 of 1, from 526 to 590: score 97.7, E = 7.5e-29
*->reIdWdkLEnkeiePPFKPkiksprDtsNFDkeFTrekPvLTPvDsv
IdW+ LE+k + PP+ P + s+rD+ FD +FT+e P+L+P++ +
F09E5.1 526 --IDWEALEQKAVAPPYHPAVESDRDLTHFDHQFTDELPQLSPDNPD 570
lirsiDQeeFrGFSYvnsPersf<-*
+i++iDQ+eF GF+Yvn P
F09E5.1 571 VIARIDQSEFDGFEYVN-PL--Q 590