Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/F10F2.2
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Query: F10F2.2 CE17651 Phosphoribosylformylglycinamidine synthase status:Partially_confirmed SW:Q19311 protein_id:CAA84656.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
AIRS_C AIR synthase related protein, C-terminal dom 177.9 1.2e-52 2
AIRS AIR synthase related protein, N-terminal dom 71.0 2.1e-18 1
CitF Citrate lyase, alpha subunit (CitF) 2.5 4.5 1
CemA CemA family 2.4 9.8 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CitF 1/1 237 248 .. 457 468 .] 2.5 4.5
AIRS 1/1 294 426 .. 56 179 .] 71.0 2.1e-18
AIRS_C 1/2 436 595 .. 1 194 [] 90.2 3.4e-26
AIRS_C 2/2 839 996 .. 1 194 [] 91.3 1.6e-26
CemA 1/1 1315 1337 .. 19 41 .. 2.4 9.8
Alignments of top-scoring domains:
CitF: domain 1 of 1, from 237 to 248: score 2.5, E = 4.5
*->RDGSliDvvyqV<-*
RDGSl+ ++++
F10F2.2 237 RDGSLMKTIRET 248
AIRS: domain 1 of 1, from 294 to 426: score 71.0, E = 2.1e-18
*->pgLafttDgvGTKLviaplffdpytiGadaVagtvnDlaamG.GAeP
++L+ +++++ + p+++ p++++ ++++g ++D+ a+G+GA
F10F2.2 294 SHLIYSAETH-----NFPTAVCPFQGATTGTGGRIRDIHATGrGAYE 335
lalldylafgegldpevlqPwEd.g..........aqivkeavkGiadgc
+a++ +++fg+++ p+ PwEd+ + +++ +++a+i+ ea +G +d++
F10F2.2 336 IAGTVGYSFGNLNLPGLPLPWEDeTfeyptsisepAKIAIEASNGASDYG 385
neaGvplvGGY.....eTavmpgglngydggfpdlaggcvGive<-*
n++G p+++G+ ++ ++ ++ + +++ +p++ g++G+++
F10F2.2 386 NKFGEPVISGFarsfgQRLENGE-R--CEYLKPIMFSGGIGAID 426
AIRS_C: domain 1 of 2, from 436 to 595: score 90.2, E = 3.4e-26
*->kpGDvlillgstgkktgrsGlhGnglslvrklleesglpdsdepfgp
+p ++++ +g+ +++r+G++G++ s+v ++ ++ +d ++
F10F2.2 436 APHQKVVKIGG---PVYRIGVGGGAASSVSVQGNRENQLD-----FA 474
avqitlgdplleptliyvvlllaalgetgglvkamhDitgGGLagalaEm
avq +gd+++ +l +vv+++a++ g++ a+hD ++GG +++ E+
F10F2.2 475 AVQ--RGDAEMGGKLHRVVRACAERIG-GNPLMAIHDQGAGGNGNVIKEL 521
apagsglGaeidldrsaeIPvweevpvfeelmkaGnrvlglemlfsenqG
+++ +G+++ d ++ +e ++ e++ +e+q+
F10F2.2 522 VEG---CGVTVKSD---------TFQLGDES------ISLRELWTAEYQE 553
rglvvvvpeeaveevlailekeglpegieaavIGeVtaggglelivk<-*
++v++ +++ i ++e + + ++v+GeV+++++++l k
F10F2.2 554 NDAALVDASLL-DALQTISKREKC--H--VSVVGEVEKEQRVKLLGK 595
AIRS_C: domain 2 of 2, from 839 to 996: score 91.3, E = 1.6e-26
*->kpGDvlillgstgkktgrsGlhGnglslvrklleesglpdsdepfgp
pG +++ ++ ++ ++ + +l+G++l +v+ ++ ++ ++ ++ +
F10F2.2 839 VPGSKILWIKIGS-SEEKMRLGGSALAQVYSQIGDDCPD----IENF 880
avqitlgdplleptliyvvlllaalgetgglvkamhDitgGGLagalaEm
+++ +++ + l ++ l+ ++++ + a+hDi++GGL+ a+ Em
F10F2.2 881 SEI-SKVFSIVQQLLNREELAGPLRKP---IILAGHDISDGGLLTAILEM 926
apagsglGaeidldrsaeIPvweevpvfeelmkaGnrvlglemlfsenqG
a+a ++++++id+ +p + + ++++lf+e++G
F10F2.2 927 AFA-GNVSIDIDIK----------PPNQN--------IKPIDILFAEECG 957
rglvvvvpeeaveevlailekeglpegieaavIGeVtaggglelivk<-*
++l+v pe++ l i++++g+ ++++IG++ a g+ ++vk
F10F2.2 958 ILLEVSNPENV----LHIFSEAGI----KCQEIGKASAVFGPDAHVK 996
CemA: domain 1 of 1, from 1315 to 1337: score 2.4, E = 9.8
*->vPllVsflsKkfvLePwieyfWN<-*
vP+ f K+ L+Pwi++f+N
F10F2.2 1315 VPWNARFDQKTVALSPWIKMFRN 1337