Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/F10F2.1
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Query: F10F2.1 CE00946 WD domain, G-beta repeat (2 domains) status:Partially_confirmed TR:Q19317 protein_id:CAA86337.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
Beach Beige/BEACH domain 734.8 3.7e-217 1
WD40 WD domain, G-beta repeat 63.0 4.1e-16 4
Fe_dep_repr_C Iron dependent repressor, metal binding 9.1 0.91 1
WCCH WCCH motif 5.1 8.2 1
DUF144 Domain of unknown function DUF144 3.5 6.2 1
HSP90 Hsp90 protein 2.1 8.6 1
DUF286 Caenorhabditis protein of unknown funct 1.6 9.7 1
Herpes_gE Alphaherpesvirus glycoprotein E 0.9 5.8 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
HSP90 1/1 22 42 .. 522 542 .] 2.1 8.6
Herpes_gE 1/1 325 338 .. 1 14 [. 0.9 5.8
WCCH 1/1 630 654 .. 1 25 [] 5.1 8.2
Fe_dep_repr_C 1/1 643 672 .. 43 73 .] 9.1 0.91
DUF286 1/1 1958 1966 .. 267 275 .] 1.6 9.7
Beach 1/1 1850 2127 .. 1 287 [] 734.8 3.7e-217
WD40 1/4 2278 2320 .. 1 39 [] 31.7 3.2e-07
WD40 2/4 2339 2377 .. 1 39 [] 23.8 5.6e-05
WD40 3/4 2429 2456 .. 11 39 .] 9.4 0.73
WD40 4/4 2460 2498 .. 1 39 [] 2.3 74
DUF144 1/1 2490 2511 .. 1 22 [. 3.5 6.2
Alignments of top-scoring domains:
HSP90: domain 1 of 1, from 22 to 42: score 2.1, E = 8.6
*->eaeeteeaeedaedskmEevD<-*
e++ +e +e ++e+s mE+vD
F10F2.1 22 EIPVEEGEEVNDEESNMETVD 42
Herpes_gE: domain 1 of 1, from 325 to 338: score 0.9, E = 5.8
*->PlnngtpytegWtf<-*
P++++ py gWtf
F10F2.1 325 PPIKTMPYQQGWTF 338
WCCH: domain 1 of 1, from 630 to 654: score 5.1, E = 8.2
*->piwqpCccphCprHkqkkgmdqqah<-*
+i +C + +p H + k+++q +h
F10F2.1 630 LIISSCLQKASPSHLSMKVLEQLIH 654
Fe_dep_repr_C: domain 1 of 1, from 643 to 672: score 9.1, E = 0.91
*->vlsdelerrLdrllrfpeecPhgkpdWIPgl<-*
+ls ++++L ++ +f +cP+g+p +++l
F10F2.1 643 HLSMKVLEQLIHIAKFLLRCPAGGP-LLKHL 672
DUF286: domain 1 of 1, from 1958 to 1966: score 1.6, E = 9.7
*->PvtsmlvNv<-*
P+ sm++N+
F10F2.1 1958 PFASMFINL 1966
Beach: domain 1 of 1, from 1850 to 2127: score 734.8, E = 3.7e-217
*->TkRWqrGeISNFeYLmhLNtlAGRsyNDLsQYPVFPWIlADYtSesL
+++Wq++eISNF+YLm+LNt+AGR++NDLsQYPVFPWIl++YtS++L
F10F2.1 1850 CAKWQKREISNFDYLMFLNTVAGRTFNDLSQYPVFPWILTNYTSDTL 1896
DLsnPstFRdLSKPiGAQspeReeqFleRYesledpeekevppFHYGtHY
DLs++s+FRdLSKPiGA+s++R+++F++RY+s++d++ vp+FHYGtHY
F10F2.1 1897 DLSVASNFRDLSKPIGALSEARRKFFNDRYTSWDDDQ---VPAFHYGTHY 1943
SSagiVlfYLiRlePFteefLaLQgGkFDhADRlFhSieetWrsaslenm
S+++++l++L+R+ePF+++f++L++GkFDh+DR++hSi+++W++ +++++
F10F2.1 1944 STPAFTLNWLLRVEPFASMFINLHDGKFDHPDRITHSIKDSWDR-CQRDS 1992
tDVKELIPEFFyLPEfLvNrngfDlGvrQnGekVnDVdLPPWAkgDEKAd
+DVKELIPE+FyLPE+++N+++f+lG+r++G++V+DV+LPPWA+ +
F10F2.1 1993 HDVKELIPELFYLPEMFRNSSKFNLGRRADGTPVDDVVLPPWAE-----S 2037
PeeFiqkhReALESdYVSahLHeWIDLIFGYKQrGkeAvkAiNVFhhltY
Pe+F+++hR+ALESd VS++L++WIDLIFGYKQrG+eAv+A+NVF+hltY
F10F2.1 2038 PEHFVLMHRQALESDLVSCQLNQWIDLIFGYKQRGAEAVRATNVFYHLTY 2087
eGaVDldsieDPverrAieaqIknFGQTPkQLFtkPHPkR<-*
eG+V+++++e+P +++Aie+qI++FGQTP+QL+t++HP+R
F10F2.1 2088 EGTVTPKMAETPGQVAAIEQQILSFGQTPSQLLTEAHPPR 2127
WD40: domain 1 of 4, from 2278 to 2320: score 31.7, E = 3.2e-07
*->geclatl.gHtspvtcvafspd...sgpylasgSrDgtiklWd<-*
g + + +gH + vtc+a s + s +y+++gS D+t+ lW+
F10F2.1 2278 GRVRQAVyGHGDVVTCIARSETslfSDCYVVTGSMDCTVVLWH 2320
WD40: domain 2 of 4, from 2339 to 2377: score 23.8, E = 5.6e-05
*->geclatl.gHtspvtcvafspdsgpylasgSrDgtiklWd<-*
++ ++l+gH+++++++++s + +++sg++Dg i +
F10F2.1 2339 PSPRSILtGHEASISALCVSAE-HGLVVSGCEDGVILIHT 2377
WD40: domain 3 of 4, from 2429 to 2456: score 9.4, E = 0.73
*->spvtcvafspdsgpylasgSrDgtiklWd<-*
+ ++cv + d g++ ++g +g i +W
F10F2.1 2429 DKIECVTVTRD-GEFAVTGAVNGRINIWR 2456
WD40: domain 4 of 4, from 2460 to 2498: score 2.3, E = 74
*->geclatl.gHtspvtcvafspdsgpylasgSrDgtiklWd<-*
+ l+t++ +s+v++va++ + ++++ g + g i +++
F10F2.1 2460 LTKLYTYqPLNSAVRSVAVVAS-HRFILGGLDSGAIVVFN 2498
[output cut off at A = 10 top alignments]