Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm2/seq/F10F2.2
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Query:  F10F2.2  CE17651   Phosphoribosylformylglycinamidine synthase status:Partially_confirmed SW:Q19311 protein_id:CAA84656.1

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
AIRS_C   AIR synthase related protein, C-terminal dom   177.9    1.2e-52   2
AIRS     AIR synthase related protein, N-terminal dom    71.0    2.1e-18   1
CitF     Citrate lyase, alpha subunit (CitF)              2.5        4.5   1
CemA     CemA family                                      2.4        9.8   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
CitF       1/1     237   248 ..   457   468 .]     2.5      4.5
AIRS       1/1     294   426 ..    56   179 .]    71.0  2.1e-18
AIRS_C     1/2     436   595 ..     1   194 []    90.2  3.4e-26
AIRS_C     2/2     839   996 ..     1   194 []    91.3  1.6e-26
CemA       1/1    1315  1337 ..    19    41 ..     2.4      9.8

Alignments of top-scoring domains:
CitF: domain 1 of 1, from 237 to 248: score 2.5, E = 4.5
                   *->RDGSliDvvyqV<-*
                      RDGSl+ ++++
     F10F2.2   237    RDGSLMKTIRET    248

AIRS: domain 1 of 1, from 294 to 426: score 71.0, E = 2.1e-18
                   *->pgLafttDgvGTKLviaplffdpytiGadaVagtvnDlaamG.GAeP
                      ++L+ +++++     + p+++ p++++ ++++g ++D+ a+G+GA
     F10F2.2   294    SHLIYSAETH-----NFPTAVCPFQGATTGTGGRIRDIHATGrGAYE 335

                   lalldylafgegldpevlqPwEd.g..........aqivkeavkGiadgc
                   +a++ +++fg+++ p+   PwEd+  + +++ +++a+i+ ea +G +d++
     F10F2.2   336 IAGTVGYSFGNLNLPGLPLPWEDeTfeyptsisepAKIAIEASNGASDYG 385

                   neaGvplvGGY.....eTavmpgglngydggfpdlaggcvGive<-*
                   n++G p+++G+ ++ ++  ++ +    +++ +p++  g++G+++
     F10F2.2   386 NKFGEPVISGFarsfgQRLENGE-R--CEYLKPIMFSGGIGAID    426

AIRS_C: domain 1 of 2, from 436 to 595: score 90.2, E = 3.4e-26
                   *->kpGDvlillgstgkktgrsGlhGnglslvrklleesglpdsdepfgp
                      +p ++++ +g+   +++r+G++G++ s+v  ++ ++  +d     ++
     F10F2.2   436    APHQKVVKIGG---PVYRIGVGGGAASSVSVQGNRENQLD-----FA 474

                   avqitlgdplleptliyvvlllaalgetgglvkamhDitgGGLagalaEm
                   avq  +gd+++  +l +vv+++a++   g++  a+hD ++GG  +++ E+
     F10F2.2   475 AVQ--RGDAEMGGKLHRVVRACAERIG-GNPLMAIHDQGAGGNGNVIKEL 521

                   apagsglGaeidldrsaeIPvweevpvfeelmkaGnrvlglemlfsenqG
                   +++   +G+++  d           ++ +e       ++  e++ +e+q+
     F10F2.2   522 VEG---CGVTVKSD---------TFQLGDES------ISLRELWTAEYQE 553

                   rglvvvvpeeaveevlailekeglpegieaavIGeVtaggglelivk<-*
                      ++v++    +++  i ++e +  +  ++v+GeV+++++++l  k
     F10F2.2   554 NDAALVDASLL-DALQTISKREKC--H--VSVVGEVEKEQRVKLLGK    595

AIRS_C: domain 2 of 2, from 839 to 996: score 91.3, E = 1.6e-26
                   *->kpGDvlillgstgkktgrsGlhGnglslvrklleesglpdsdepfgp
                       pG +++ ++ ++ ++ + +l+G++l +v+ ++ ++ ++    ++ +
     F10F2.2   839    VPGSKILWIKIGS-SEEKMRLGGSALAQVYSQIGDDCPD----IENF 880

                   avqitlgdplleptliyvvlllaalgetgglvkamhDitgGGLagalaEm
                   +++ +++     + l ++ l+ ++++     + a+hDi++GGL+ a+ Em
     F10F2.2   881 SEI-SKVFSIVQQLLNREELAGPLRKP---IILAGHDISDGGLLTAILEM 926

                   apagsglGaeidldrsaeIPvweevpvfeelmkaGnrvlglemlfsenqG
                   a+a ++++++id+           +p  +        + ++++lf+e++G
     F10F2.2   927 AFA-GNVSIDIDIK----------PPNQN--------IKPIDILFAEECG 957

                   rglvvvvpeeaveevlailekeglpegieaavIGeVtaggglelivk<-*
                   ++l+v  pe++    l i++++g+    ++++IG++ a  g+ ++vk
     F10F2.2   958 ILLEVSNPENV----LHIFSEAGI----KCQEIGKASAVFGPDAHVK    996

CemA: domain 1 of 1, from 1315 to 1337: score 2.4, E = 9.8
                   *->vPllVsflsKkfvLePwieyfWN<-*
                      vP+   f  K+  L+Pwi++f+N
     F10F2.2  1315    VPWNARFDQKTVALSPWIKMFRN    1337



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