Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/F13D12.2
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Query: F13D12.2 CE02181 locus:ldh-1 L-lactate dehydrogenase status:Confirmed SW:Q27888 protein_id:CAA88944.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
ldh lactate/malate dehydrogenase, NAD binding do 240.6 2.2e-68 1
ldh_C lactate/malate dehydrogenase, alpha/beta C-t 236.4 4.2e-67 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
ldh 1/1 18 161 .. 1 156 [] 240.6 2.2e-68
ldh_C 1/1 163 329 .. 1 175 [. 236.4 4.2e-67
Alignments of top-scoring domains:
ldh: domain 1 of 1, from 18 to 161: score 240.6, E = 2.2e-68
*->kkptKVaVvGAGGgVGsslAfalanlqgladEqpIiLvLvDinkamd
+ KV+VvG+G +VG+++A++++ +q la E L LvD++ d
F13D12.2 18 NSHGKVTVVGVG-QVGMACAYSIL-QQNLANE----LCLVDVVA--D 56
kaeGvamDLqHgsaflsvpgiiggdqdyealkDaDvVvItAGvpqkPGeT
k++G++mDLqHg af++ + + +d dy++++++++ v+tAG++q++GeT
F13D12.2 57 KLKGEMMDLQHGLAFTR-HCTVKADTDYSITAGSKLCVVTAGARQREGET 105
RlDLlnrNakIfksivpaiaksapdaivlVvsNPVDiltyiawkvsKKaG
Rl L++rN+ Ifk i+p+++k++pd ++lVvsNPVD+lty++wk+s G
F13D12.2 106 RLSLVQRNVEIFKGIIPQLVKYSPDTCILVVSNPVDVLTYVTWKLS---G 152
lpkervigs<-*
lp+erv+gs
F13D12.2 153 LPRERVFGS 161
ldh_C: domain 1 of 1, from 163 to 329: score 236.4, E = 4.2e-67
*->TnLDtaRfrtllAeklgvkdPrsvhvyiiGEHGDsevPvWShAnvgG
TnLD+aRfr+ll+ekl++ +P+s+h++iiGEHGDs+v+vWS++nv+G
F13D12.2 163 TNLDSARFRFLLSEKLNI-APSSCHGWIIGEHGDSSVAVWSGVNVAG 208
vpleslvkelgedsd.dele.elierVqdaAyeVIeaKaGaGsTtysiAl
v l + + ge +d++++e e+++ V+d+Aye+I++K G+T+++i+l
F13D12.2 209 VTLHEIKPDIGEKTDnEHWEaEIHKKVVDSAYEIIKLK---GYTSWAIGL 255
AlAriaeaiLrdtpEnrvlpvsvyldGfyGipddelvyfsvPvvLgrnGv
++A+ia i+++ ++v+ s+ ++Gf+Gi+dd vy+s+PvvLg+ G+
F13D12.2 256 SVAKIAQGIFSNS--RNVFALSTNVKGFHGINDD--VYLSLPVVLGSAGL 301
eevvegllpLndeEreklekSadtLkkiie<-*
vv+ L++ E +kl+ Sa+ L ++++
F13D12.2 302 THVVK--QQLTEAEVQKLHNSAKALLEVQN 329