Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/F13D12.6
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Query: F13D12.6 CE02185 serine carboxypeptidase status:Confirmed SW:P52715 protein_id:CAA88947.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
serine_carbpept Serine carboxypeptidase 388.6 6.2e-113 1
abhydrolase alpha/beta hydrolase fold 5.4 1.1 1
A4_EXTRA Amyloid A4 extracellular domain 3.6 0.024 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
A4_EXTRA 1/1 138 151 .. 1 14 [. 3.6 0.024
abhydrolase 1/1 428 449 .. 212 232 .] 5.4 1.1
serine_carbpept 1/1 28 451 .. 1 507 [] 388.6 6.2e-113
Alignments of top-scoring domains:
A4_EXTRA: domain 1 of 1, from 138 to 151: score 3.6, E = 0.024
*->gaaeakaePQiAml<-*
++a++ +e+ +A++
F13D12.6 138 QTASENWEALVAFF 151
abhydrolase: domain 1 of 1, from 428 to 449: score 5.4, E = 1.1
*->dagHlallekpeevaeli.kfl<-*
+agH++ +kp+ ++i+ fl
F13D12.6 428 GAGHMVPTDKPAVAEHIIqSFL 449
serine_carbpept: domain 1 of 1, from 28 to 451: score 388.6, E = 6.2e-113
*->PgllgilpnVDvkqYSGYltvndthgknlFYwffESrnDPkqdPvvl
Pg + ++n +kqYSGY+ v+ + + l+Ywf+ES+ +P+ dPv+l
F13D12.6 28 PGAP--ISN--FKQYSGYYNVGTKKNHMLHYWFVESQSNPSTDPVLL 70
WLNGGPGCSSllGlfyEnGPfsIssdgSKSLpslslNPYSWnnvanmIYl
WL+GGPGCS+l +l++E GP +++ dg ++l NPYSWn++a+++ l
F13D12.6 71 WLTGGPGCSGLSALLTEWGPWNVNTDG----ATLRTNPYSWNKNASILTL 116
DQPvGVGFSYsdsdddytttndveaakDlynfLqdFFqlFPellkndFyI
+ P+GVG+SY +d + t+d ++a+ ++++L +FF +FP++++ndFy
F13D12.6 117 EAPAGVGYSYA--TDNNIATGDDQTASENWEALVAFFNEFPQYKGNDFYV 164
aGESYAGhYiPtfAseivqgnkknpgpniNLkGlaIGNGlTDpliQynay
+GESY+G+Y+Pt+ i+ +++ +iN+kGlaIGNG ++ +++
F13D12.6 165 TGESYGGIYVPTLVQTILDR---QSQSHINIKGLAIGNGCVSANEGVDSL 211
vpfayehggelsvLiseeyskisksfprClaaikaCqgsnsdnsctnati
v f+y hg v + + + + ++C+ + d+ + +
F13D12.6 212 VNFLYHHG----VVDQAKWEHM----------KTSCCHNDTDACPWHSFS 247
vYPiWRPEYnFs.CntallkpessvGkdglNvYdirepCegsslskfvkl
+ Fs C + + ++ + glN+Y+ +++C s s
F13D12.6 248 E---------FSaCGEFVEATQQTAWNGGLNPYNMYADCISTSAS----- 283
ketklvqsfdnlgttlkpvkvrpralmrawdlrakvkarrdplCypnlsy
+ ++ + +n+ y
F13D12.6 284 -----------------------------------FRFGMEYERRFNKKY 298
.....SGVPCmSDevlskYLnnpdVrkAlgagrleyqstswdgCnfdvyq
+++ VPC+ + ++++YLn++dVrkAlg ++++ + w +C++ +
F13D12.6 299 tpevlGTVPCLDESPVTNYLNRQDVRKALG--IPSSLP-AWSICSNAISY 345
kfldtgdwmrsflvkllslLeqgyrvLiYAGDlDmiCNwlGneawvnsle
+ + + m s +++ + +++ +Y+GD+D++CN l+ ++++++l+
F13D12.6 346 GYKRQYGDMTSRVLNAVN--NNNLKMMLYNGDVDLACNALMGQRFTDKLG 393
wsGkkqFqasswrPWlvdgadseqvaGfvktyek.hltFltvrgAGHmVP
+ + + ++v+g q++G+v y+ ++ tF+tvrgAGHmVP
F13D12.6 394 LT-----LSKKKTHFTVKG----QIGGYVTQYKGsQVTFATVRGAGHMVP 434
ydkPqaALqmvkrwiaG<-*
+dkP+ A +++ +
F13D12.6 435 TDKPAVAEHIIQSFLFN 451