Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/F15B9.4
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Query: F15B9.4 CE30954 status:Partially_confirmed TN:CAB01425 protein_id:CAB01425.2
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
FH2 Formin Homology 2 Domain 350.9 1.3e-101 1
DUF252 Putative tyrosine phosphatase family 7.1 0.46 1
HNF-1A_C Hepatocyte nuclear factor 1 (HNF-1), alpha i 5.5 1.6 1
PAX 'Paired box' domain 3.0 9.8 1
RTX RTX N-terminal domain 1.4 4.3 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
HNF-1A_C 1/1 114 124 .. 1 11 [. 5.5 1.6
DUF252 1/1 624 675 .. 31 101 .. 7.1 0.46
RTX 1/1 815 850 .. 1 38 [. 1.4 4.3
FH2 1/1 305 905 .. 24 486 .] 350.9 1.3e-101
PAX 1/1 952 966 .. 111 125 .] 3.0 9.8
Alignments of top-scoring domains:
HNF-1A_C: domain 1 of 1, from 114 to 124: score 5.5, E = 1.6
*->vlTsDpeahtD<-*
vlT D+e++tD
F15B9.4 114 VLTKDSETQTD 124
DUF252: domain 1 of 1, from 624 to 675: score 7.1, E = 0.46
*->LrstLrLktIisLspEpypqdnlqeKFlesehIklyhiamegnkdpd
+++ LrL+ ++ +s E+ + + F I+l++ +++ +++
F15B9.4 624 NKH-LRLRIELFISKENVTAEIGK--F--QSQIELLQTGCQLARG-- 663
ddkikikknpfvnipshllrraLk<-*
+i++ llr++L+
F15B9.4 664 ------------EIVQVLLRKCLQ 675
RTX: domain 1 of 1, from 815 to 850: score 1.4, E = 4.3
*->tlaniKsqlkqglkstknklksagssaKeaLkkAgssl<-*
tl+ i ++l+q+ k + + k+a+ +K+ L+ A+s +
F15B9.4 815 TLQAIFETLEQSMKIVSDAVKQAA--TKNRLTRASSLV 850
FH2: domain 1 of 1, from 305 to 905: score 350.9, E = 1.3e-101
*->ad.aP..........................................
a+++P+++++ + +++ +++++ ++ +++ ++++++++ + +
F15B9.4 305 APpPPgppssllplintnapppppmpsinghapnppppppllgiapm 351
..................................................
+++ +++++ ++ + +++ ++++++++ + +++++++++ + + ++
F15B9.4 352 stnapppppmpgmaplstgaptppppppvgmanggpppppplpldllkga 401
..................................................
+ ++ ++++++++++++++ +++ ++ ++++++++ +++ ++
F15B9.4 402 vaglksvpggppppppppppsfmfngkvpnafspgtstspvlspgvvksa 451
........................PdeksqktvWgttlddeieetklLen
++++++ + ++ + + ++ + ++++ ++ +d+ +e + +
F15B9.4 452 vvyrkqkktafvrwpkltmqmqdaGTVFND-SLC---VDFNEDERTK--M 495
egllde.....lEelFamkektkkakkalsekksk....lmkkkvsknfk
e +++e + ++l +++ + ++++ + k+l ++s+++ ++m++++++n++
F15B9.4 496 EEVFEEapvkqLNRKI-AGSVGRAFGKSLRATTSSsefnPMSARSPTNPQ 544
ildpkrsqnppleIllrslhCdmsfeetvivvailevDevdvlsedllen
+l+++++++ +eIl+++l+ +m+f++ ++++++++D+ + +++dl+++
F15B9.4 545 VLVSPKALT--IEILIKKLK-PMEFTQ--LIEKLDANDT-EGIKVDLMTT 588
LlkfaPYskteeelkklreykedkekdleeLsradqiFlllisnLipyle
L++++P ++ el+++++++++ ++++ +dq F+++i++ +++l+
F15B9.4 589 LNNNFP---DKVELDPFLKVEYA-----TLTHASDQ-FCWHIAR-NKHLR 628
eRmnallfksnfeeevedLkpkiekvtaAseeLreSkkfkklLeliLaiG
R++ ++ k+n++ e+ +++ +ie++++ ++ r + ++ lL+ +L++G
F15B9.4 629 LRIELFISKENVTAEIGKFQSQIELLQTGCQLAR-GEIVQVLLRKCLQYG 677
NYMNagsrrRgqAkGFkLssLlkLldtKsadnk..tTLLHyivkiirkky
NY N+gs++ ++A GF++s+L++Ll++K++ ++++++L+++iv ++++ +
F15B9.4 678 NYLNQGSMF-AEAAGFQFSYLIQLLQMKGKGQHtsVRLVDLIVAYCDLAT 726
pdllnFeddlhhvdkaSsrkvnleqlekdvkslgrqiknlEtsldkgkLs
++++++++++++v+ ++nl++le++v++++r +++kL+
F15B9.4 727 AEVEEVQSRMGSVR-----PLNLKDLEDVVGQVQR---------SIRKLE 762
dpe.fhpdDkflevmspflkaakekfdkLqkdlkdmktllenlveyygEd
++ +++++++++++++pf+++++ek++++q+ l+d+k + ++l++y++
F15B9.4 763 GQLrSSSEETLIAAYEPFVNQTNEKLQNVQNGLSDLKARETELQVYLCAG 812
pkddlspneFFkrfneflkefkkAvkeNekkekeeelrrrrkla.kekae
+ ++ + +F+++++++k+ ++Avk+ ++++r ++a+++++
F15B9.4 813 N---MTLQAIFETLEQSMKIVSDAVKQA-------ATKNRLTRAsSLVTL 852
keqskskqke......knplmdfeae..pverdfkgvldsalleklrtga
+++s+s++++++++ +++m++++++ pve+++k++l+s + ++r+++
F15B9.4 853 PTSSVSRRSLregevlSRQSMALKTRdlPVEELKKMFLHS-SFGPQRAKR 901
afrr<-*
+ ++
F15B9.4 902 SVAS 905
PAX: domain 1 of 1, from 952 to 966: score 3.0, E = 9.8
*->kdnvPsvssisRilR<-*
+++ Psvs+i R +R
F15B9.4 952 QQEPPSVSAIRRDIR 966