Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/F20C5.2b
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Query: F20C5.2b CE03239 locus:klp-11 kinesin status:Partially_confirmed TN:CAD36488 protein_id:CAD36488.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
kinesin Kinesin motor domain 513.2 1.9e-150 2
Thymosin Thymosin beta-4 family 8.7 0.59 1
GED Dynamin GTPase effector domain 8.2 0.42 1
ELK ELK domain 6.2 3.1 1
Paxillin Paxillin family 5.1 0.91 1
Troponin Troponin 3.9 7.1 1
DUF260 Protein of unknown function DUF260 2.8 1.4 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
kinesin 1/2 58 314 .. 1 339 [. 490.4 1.4e-143
kinesin 2/2 315 330 .. 358 373 .] 23.9 4.4e-06
ELK 1/1 338 359 .. 1 22 [] 6.2 3.1
Troponin 1/1 344 362 .. 168 186 .] 3.9 7.1
DUF260 1/1 344 375 .. 89 119 .] 2.8 1.4
Thymosin 1/1 405 425 .. 21 41 .] 8.7 0.59
GED 1/1 502 521 .. 78 97 .] 8.2 0.42
Paxillin 1/1 766 776 .. 210 220 .] 5.1 0.91
Alignments of top-scoring domains:
kinesin: domain 1 of 2, from 58 to 314: score 490.4, E = 1.4e-143
*->ktFtFDkVFdpestqefvyeetakPlvesvleGyNgtiFAYGQTGSG
k FtFD+++d++stq + yeet ++lv+svl+GyN+tiFAYGQTG+G
F20C5.2b 58 KDFTFDAIYDENSTQSDLYEETFRDLVDSVLNGYNATIFAYGQTGTG 104
KTYTMeGppdsdkegsgnptdsyttpeeepGiiPRaledlFerieerker
KT+TMeG+++ ++e++G+i+ +++++Fe++ +++
F20C5.2b 105 KTHTMEGKSS---------------DPEQRGVIYKCIDHIFEHM-AASHN 138
kgvfPklnwellnsqetligvsfdrglssdlyvndlefsvrvSylEIYNE
e++vr+SylEIY+E
F20C5.2b 139 -----------------------------------QEYLVRASYLEIYQE 153
kirDLLspsppqagspsksnekkkkpgvpLrireDpkrGgkmdgvyVeGL
++rDLL+ + ++k+ L+i+e p++G vyV++L
F20C5.2b 154 ELRDLLEAE-------------SNKK---LEIKERPDGG-----VYVKDL 182
tevpVssaeevlelLelGnknRtvasTamNerSSRSHaiFtitveqrnrd
t+ +++ e++e++ +Gn +R+v+ T+mNe+SSRSHaiF+itve +++
F20C5.2b 183 TSKLTRTVGEIHEVMIRGNGHRSVGRTNMNEHSSRSHAIFIITVECSRIG 232
segskvtgkdnsgeesvrvskLnLVDLAGSERaskTgatGAggrRLkEga
++ge++++v++LnLVDLAGSER+skTg A+g+R+kE++
F20C5.2b 233 ----------EDGESHITVGRLNLVDLAGSERQSKTG---ATGERFKEAT 269
nINkSLsaLGnVInALa.....HiPYRDSKLTrLLqDSLGGGaNsKT<-*
+IN+SLsaLGnVI+AL++ ++ HiPYRDSKLTrLLqDSLGG NsKT
F20C5.2b 270 KINLSLSALGNVISALVdaksaHIPYRDSKLTRLLQDSLGG--NSKT 314
kinesin: domain 2 of 2, from 315 to 330: score 23.9, E = 4.4e-06
*->ETlsTLrFAsRAknIk<-*
ETl TLr+A+RAknIk
F20C5.2b 315 ETLGTLRYANRAKNIK 330
ELK: domain 1 of 1, from 338 to 359: score 6.2, E = 3.1
*->eLKeeLlrKYsgylssLkeEfl<-*
+ K+ Llr +++++ L+e +
F20C5.2b 338 DPKDALLREFQEEIEMLREQLK 359
Troponin: domain 1 of 1, from 344 to 362: score 3.9, E = 7.1
*->lraekkeaesLRanlKeVk<-*
lr + e e LR++lK++k
F20C5.2b 344 LREFQEEIEMLREQLKQRK 362
DUF260: domain 1 of 1, from 344 to 375: score 2.8, E = 1.4
*->ieslqaeLalvkselstyrgdpqd.qvpqesp<-*
+++ q+e+++++++l++ ++ d+ + +++
F20C5.2b 344 LREFQEEIEMLREQLKQRKTRSRDgATQSFYD 375
Thymosin: domain 1 of 1, from 405 to 425: score 8.7, E = 0.59
*->EtqEKnpLPtKEtiEqEKqae<-*
E qEK L KE iEq + ae
F20C5.2b 405 EIQEKHDLLEKERIEQARVAE 425
GED: domain 1 of 1, from 502 to 521: score 8.2, E = 0.42
*->kelkkrLelLkkArqiisev<-*
k+lkk+L L++Ar +i +v
F20C5.2b 502 KKLKKMLIKLRQARNEIRDV 521
Paxillin: domain 1 of 1, from 766 to 776: score 5.1, E = 0.91
*->SSPQrvNaSeq<-*
SSPQr Na e+
F20C5.2b 766 SSPQRHNATER 776