Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/F27D9.5
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Query: F27D9.5 CE04451 Propionyl-coA carboxylase alpha chain precursor status:Partially_confirmed TR:Q19842 protein_id:AAA93384.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
CPSase_L_D2 Carbamoyl-phosphate synthase L chain, 361.9 7e-105 1
Biotin_carb_C Biotin carboxylase C-terminal domain 204.2 1.4e-58 1
CPSase_L_chain Carbamoyl-phosphate synthase L chain, 167.0 3.2e-46 1
biotin_lipoyl Biotin-requiring enzyme 80.1 4.2e-21 1
HlyD HlyD family secretion protein 6.3 1.5 2
ATP-grasp ATP-grasp domain 3.8 5.3 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CPSase_L_chain 1/1 48 160 .. 1 129 [] 167.0 3.2e-46
ATP-grasp 1/1 198 263 .. 125 190 .] 3.8 5.3
CPSase_L_D2 1/1 162 376 .. 1 262 [] 361.9 7e-105
Biotin_carb_C 1/1 383 491 .. 1 118 [] 204.2 1.4e-58
HlyD 1/2 654 688 .. 1 35 [. 0.8 47
biotin_lipoyl 1/1 656 723 .. 1 75 [] 80.1 4.2e-21
HlyD 2/2 700 724 .] 10 34 .. 5.3 3
Alignments of top-scoring domains:
CPSase_L_chain: domain 1 of 1, from 48 to 160: score 167.0, E = 3.2e-46
*->didkvLianrGeiaigqarefdysGYEtFderiqavaalseedLant
++dk+LianrGeia++++ +++ +G i++va++s++d n+
F27D9.5 48 KFDKILIANRGEIACRVIKTARAMG-------IKTVAVHSDVD-SNS 86
ilvnpadatvqtgpglADkvYflpktylnvdkIIeaarpdgvlathgGyG
++v++ad++v++g+++ ++k+yl d+I+ a + +g++a+h+GyG
F27D9.5 87 LHVKMADEAVCVGEAP------TAKSYLRADRILQAVEDTGAQAVHPGYG 130
fLnenaeLaeagvleeygvkflGppaeaIram<-*
fL+en ++a+ ++++ g kf+Gp +aI +m
F27D9.5 131 FLSENTKFAAELEKA--GAKFIGPNSKAILDM 160
ATP-grasp: domain 1 of 1, from 198 to 263: score 3.8, E = 5.3
*->lgnfdfpavlKarrdgydGkgqyvareiakedglealkellvgara.
+g +p+++Ka+ +g Gkg +va + +++ e+ + ++ a+ +
F27D9.5 198 IG---YPVMIKASAGG-GGKGMRVAWND--KQAREGYRLSKQEAASs 238
....dlivelyvpFee.eeasllei<-*
++++++ve+++ +++e +l+
F27D9.5 239 fgddRMLVEKFIDNPRhIEMQVLCD 263
CPSase_L_D2: domain 1 of 1, from 162 to 376: score 361.9, E = 7e-105
*->DKisfkaamkeagvptvPssagPrvDtvhvDktlvVpddlYkGlves
DKi +k ++ a v +P+ +g + +
F27D9.5 162 DKIHSKKIATAARVSMIPGYDG---------------------EIAD 187
aeeAlaaAkeiGYPViIKAAfGgGGkGmriarneeelielfaqAlaeapa
++ +++ ++iGYPV+IKA++GgGGkGmr+a+n+ + +e ++++ +ea++
F27D9.5 188 EDMCVKVSRDIGYPVMIKASAGGGGKGMRVAWNDKQAREGYRLSKQEAAS 237
AFGnpqvlvEKslkgpkhiEyqVlaDahGNcItlcnrECsdqrGiRtQks
+FG++++lvEK++++p+hiE+qVl D+hGN+ +l++rECs+qr R+Qk+
F27D9.5 238 SFGDDRMLVEKFIDNPRHIEMQVLCDKHGNALWLNERECSIQR--RNQKV 285
IevAPsqtLtdeerqmlreaAvkiarhvGyvGaGTVeflldpdsgefyfI
Ie+APs + ++e r++++e+Av++a++vGy +aGTVefl+d+ +++fyf+
F27D9.5 286 IEEAPSSFVPPEMRRKMGEQAVQLAKAVGYDSAGTVEFLVDS-QRNFYFL 334
EvNpRLqVehpltekaTGypLakeqakIAlGipLpelkNivTggttAcFE
E+N+RLqVehp+te++TG++++++++++ G+pLp++
F27D9.5 335 EMNTRLQVEHPITECITGIDIVQQMLRVSYGHPLPIT------------- 371
PsLDYvVvKiprwdl<-*
++++
F27D9.5 372 ----------QEQVP 376
Biotin_carb_C: domain 1 of 1, from 383 to 491: score 204.2, E = 1.4e-58
*->EcRInAEDPakgFflPspGritayrsPeeragGpGVRvDsggvyaGy
E+R++AEDP+kgF+lPs Gr+++y +P+++ GVR+Ds g+ +G+
F27D9.5 383 ESRVYAEDPYKGFGLPSVGRLSRYVEPKHV---DGVRCDS-GIREGS 425
eIspyYDSmiaKlivwGedReeAiarMkrALkEfrIrGevkTNIpFLial
eIs+yYD++i+Kl+++G +Re+A++rM+ AL++++IrG v +NIp+L+++
F27D9.5 426 EISIYYDPLICKLVTHGDNREQALNRMQEALDNYVIRG-VTHNIPLLRDI 474
LedpdFlsGneGaFvtTkfld<-*
+++++F+ G+ +tTk+l+
F27D9.5 475 VQEKRFRTGD----ITTKYLP 491
HlyD: domain 1 of 2, from 654 to 688: score 0.8, E = 47
*->rskevqpqvsGiVieilvkeGdrVkaGqvLvqlDp<-*
s v ++ G ++ ++vk Gd V +Gq Lv +++
F27D9.5 654 LSTVVLSPMPGAIKNVNVKPGDMVSEGQELVVMEA 688
biotin_lipoyl: domain 1 of 1, from 656 to 723: score 80.1, E = 4.2e-21
*->keiksPmiGesvkegtPvaevlVkvGDkVkaGqvlcevEaMKmemei
+++ sPm+G + v Vk+GD V++Gq l++ EaMKm++ +
F27D9.5 656 TVVLSPMPGAIKN-------VNVKPGDMVSEGQELVVMEAMKMQNSL 695
pApvaGvvkeilvkeGdtVevGdpLaki<-*
A ++G vk++ vk+G+tV++G++L+++
F27D9.5 696 HAGKTGRVKAVNVKVGATVDEGEVLVEL 723
HlyD: domain 2 of 2, from 700 to 724: score 5.3, E = 3
*->sGiVieilvkeGdrVkaGqvLvqlD<-*
+G+V+ ++vk G+ V +G+vLv+l+
F27D9.5 700 TGRVKAVNVKVGATVDEGEVLVELE 724