Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm2/seq/F29D10.4
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Query:  F29D10.4  CE05763  locus:hum-1 myosin status:Partially_confirmed TR:Q19901 protein_id:CAB00095.1

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N
--------     -----------                                -----    ------- ---
myosin_head  Myosin head (motor domain)                1092.8          0   1
SH3          SH3 domain                                  65.2    2.9e-16   1
UPF0042      Uncharacterised P-loop ATPase protein fa    14.5     0.0031   1
IQ           IQ calmodulin-binding motif                  7.9        2.8   1
Replicase    Replicase family                             4.1        5.4   1
Shikimate_DH Shikimate / quinate 5-dehydrogenase          3.7        6.6   1
RNA_helicase RNA helicase                                 3.3          7   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
Shikimate_DH   1/1      67    78 ..   251   262 ..     3.7      6.6
UPF0042        1/1     101   118 ..     1    19 [.    14.5   0.0031
RNA_helicase   1/1     102   125 ..   125   148 ..     3.3        7
myosin_head    1/1      16   677 ..     1   734 []  1092.8        0
IQ             1/1     697   714 ..     4    21 .]     7.9      2.8
Replicase      1/1     736   760 ..   237   261 .]     4.1      5.4
SH3            1/1    1047  1100 .]     1    57 [.    65.2  2.9e-16

Alignments of top-scoring domains:
Shikimate_DH: domain 1 of 1, from 67 to 78: score 3.7, E = 6.6
                   *->gMLveQgaeqFe<-*
                      +ML++Qga+q+e
    F29D10.4    67    EMLLYQGAAQYE    78

UPF0042: domain 1 of 1, from 101 to 118: score 14.5, E = 0.0031
                   *->ielvivtGrSGAGKsVAlr<-*
                       + vi++G SGAGK+V ++
    F29D10.4   101    -QCVIISGESGAGKTVNAK    118

RNA_helicase: domain 1 of 1, from 102 to 125: score 3.3, E = 7
                   *->vvylhGaPGqGKSllanvlarals<-*
                      +v++ G +G GK++ a  +++ +s
    F29D10.4   102    CVIISGESGAGKTVNAKFIMNYIS    125

myosin_head: domain 1 of 1, from 16 to 677: score 1092.8, E = 0
                   *->vEDmveLtyLnEpsvlhNLKkRYksdlIYTYsGlvLvsvNPYkrLpq
                      v+Dmv+L++L+E+s+ +NLKkR  +  I TY+G+vL+svNP+k+ p
    F29D10.4    16    VDDMVLLPKLTEQSIVENLKKRLQANSIFTYIGPVLISVNPFKQMP- 61

                   iYteeiiakYrGKrryElPPHiFAiADeAYRsMlsdkeNQsilISGESGA
                    +te+ +  Y G  +yE++PHi+A+AD++YR+Ml d+e+Q+++ISGESGA
    F29D10.4    62 YFTEKEMLLYQGAAQYENAPHIYALADNMYRNMLIDNESQCVIISGESGA 111

                   GKTEntKkvmqYlAaVsggnsgngeevpsvkvgrvEdqILqsNPiLEAFG
                   GKT+n+K +m Y+  +sgg + +        v  ++d+ILqsNP+LEAFG
    F29D10.4   112 GKTVNAKFIMNYISRISGGGQ-K--------VQHIKDVILQSNPLLEAFG 152

                   NAKTtRNNNSSRFGKyieIqFdktGkivGakIenYLLEKSRVvyQtegER
                   N  T+RN NSSRFGKy eI F  +G+++G+k +n LLEKSRVv+Q+eg R
    F29D10.4   153 NSATVRNWNSSRFGKYVEIVFSRGGEPIGGKLSNFLLEKSRVVHQNEGDR 202

                   NFHIFYQLLaGasqqnlkkeLkLtndpedYhYLnqggevkpcytvdGiDD
                   NFH+FYQL+aGa+   l+ +++ +    +Y+YLn +g     +  d+ DD
    F29D10.4   203 NFHVFYQLCAGADKN-LRSTFGIG-ELQYYNYLNMSG----VFKADDTDD 246

                   segnveeFketrkAmdilGftdeeqrsIFrivAaILhlGNikFkqrrkee
                        +eF  t+ Am+++G +d++q++++rivA +Lh+GNi F ++++ +
    F29D10.4   247 G----KEFESTLHAMKVVGVNDQDQLEVLRIVATVLHIGNITFTEENNFA 292

                   aaipddnnadtkalekaaeLlGvdatelekALlsrriktGtegrkStvtk
                   a++  d       le  a+LlG+ +++ e  L+ r+++ + ++ k  +
    F29D10.4   293 AVSGKD------YLEYPAFLLGLTSADIEAKLTGRKMESKWGTQKEEIDM 336

                   pqnveQAsyARDALAKalYsRLFdWIVnrINktLdfkakegqdasfIGVL
                    +nveQAsy RDA  Ka+Y+RLFd++V+++N ++ ++  +  d++  G+L
    F29D10.4   337 KLNVEQASYTRDAWVKAIYARLFDYLVKKVNDAMNITSQSTSDNFSVGIL 386

                   DIyGFEIFekNSFEQLCINYvNEKLQQfFNhhmFklEQEEYkrEGIeWtf
                   DIyGFEIF++N+FEQ+CIN+vNEKLQQ+F+++++k+EQEEY+rEGI+Wt+
    F29D10.4   387 DIYGFEIFNNNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVREGIKWTE 436

                   IdFgdNLQpcIDLIEkKsPpGILsLLDEeClfPkaqS.GtDqtFldKLys
                   Id++dN ++++DLIE+K+PpGI+sLLD+ C   ++q +G D  +l  L +
    F29D10.4   437 IDYFDN-KIVCDLIETKRPPGIMSLLDDTCAQNHGQReGVDRQLLTTLSK 485

                   tfskhpahfekfsPrfrqkksgahFiikHYAGdVeYnvegFleKNKDpLf
                   +f +hp hf       ++  s   F+ikHYAGdV+Ynv+gF++ N+D L+
    F29D10.4   486 SFAGHP-HFG------PGSDS---FVIKHYAGDVTYNVDGFCDRNRDVLY 525

                   ddlisllksSsnpllaeLFpdeetlagpfeadpsslskkrksgskNkstg
                   +dli l+++Ss p+++ LFp           +  ++s  +
    F29D10.4   526 PDLILLMQKSSRPFIQALFP-----------ENVAASAGK---------- 554

                   kktkksnfiTvGaqfKeslneLMktLsstnLPHFvRCIkPNekKkagvfD
                         +++T + +++++ n+L++ L +++ PH+vRCIkPNe K++++++
    F29D10.4   555 ------RPTTFSTKIRTQANTLVESLMKCS-PHYVRCIKPNETKRPNDWE 597

                   aslVlhQLrclGVLEgiRIrRaGFPnRitfdeFlqRYriLapktwPkwsg
                   +s+V+hQ+ +lG+ E+iR+rRaGF++R +fd+F qRY+i++p+twP + g
    F29D10.4   598 ESRVKHQVEYLGLRENIRVRRAGFAYRRAFDKFAQRYAIVSPQTWPCFQG 647

                   dakkgeknEIvaceklLqsLnlDkgeeyrfGkTKIFFR<-*
                   d +        ace + +s  ++k ++y++GkTKIF +
    F29D10.4   648 DQQR-------ACEIICDSVHMEK-NQYQMGKTKIFVK    677

IQ: domain 1 of 1, from 697 to 714: score 7.9, E = 2.8
                   *->aikIQaawRGylaRkryk<-*
                      a +IQ+awR + aRk++
    F29D10.4   697    ARVIQKAWRQFSARKQHI    714

Replicase: domain 1 of 1, from 736 to 760: score 4.1, E = 5.4
                   *->chRgdgqlvyeatlpeiQaarGRkg<-*
                      ++ ++g+++  ++ p+ Q+  G++
    F29D10.4   736    NRNFVGDYIGLEHHPTLQSLVGKRQ    760

SH3: domain 1 of 1, from 1047 to 1100: score 65.2, E = 2.9e-16
                   *->pkvvALYDYeaeesdELsFkkGDvitvleksddgWWkgrlkgtgGke
                      p+v+A Y+Yea++ dELsF+ G++i++ +k+ +gWW g+++   +++
    F29D10.4  1047    PVVIAVYPYEAQDVDELSFEAGAEIELMNKDASGWWQGKVN---NRV 1090

                   GlvPsNYVep<-*
                   Gl+P NYV +
    F29D10.4  1091 GLFPGNYVKE    1100



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