Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/F30A10.8a
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Query: F30A10.8a CE09809 locus:stn-1 beta1-syntrophin status:Partially_confirmed TR:Q93646 protein_id:CAB03025.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
PDZ PDZ domain (Also known as DHR or GLGF) 72.8 2.7e-19 1
PH PH domain 50.7 7e-13 2
DUF355 Protein of unknown function (DUF355) 4.0 1.4 1
ELH Egg-laying hormone precursor 2.7 2.5 1
CNH CNH domain 2.6 9.9 1
Rad9 Rad9 2.4 4.1 1
7tm_2 7 transmembrane receptor (Secretin family) 2.1 8.5 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
Rad9 1/1 19 49 .. 362 397 .] 2.4 4.1
PDZ 1/1 45 127 .. 1 84 [] 72.8 2.7e-19
DUF355 1/1 141 158 .. 137 157 .] 4.0 1.4
CNH 1/1 138 169 .. 331 362 .] 2.6 9.9
ELH 1/1 130 175 .. 217 262 .] 2.7 2.5
PH 1/2 173 208 .. 53 85 .] 9.7 0.26
PH 2/2 228 340 .. 1 85 [] 41.0 3.8e-10
7tm_2 1/1 421 433 .. 261 273 .] 2.1 8.5
Alignments of top-scoring domains:
Rad9: domain 1 of 1, from 19 to 49: score 2.4, E = 4.1
*->rvlnsiaLdrgdelkeikepheeeEDeeekstvdgi<-*
rvl Ld+ ++ +++e+ e e +ek tv
F30A10.8a 19 RVL--ATLDPTAITLQTMEQNEAE---AEKRTVRVV 49
PDZ: domain 1 of 1, from 45 to 127: score 72.8, E = 2.7e-19
*->evtlekevkrgglGfsikggsdk..givvsevlpGsgaAeagGrLke
+v++ k+ ++glG+sikgg d++ +iv+s++ +G +aA+++G+L
F30A10.8a 45 TVRVVKY-DGNGLGISIKGGRDNnmPIVISKIFKG-MAADQAGELFL 89
GDvIlsvNGqdvenmsheravlaikgsggsevtLtvlRd<-*
+DvI+svNG+++ + she+av a+k +g +v L+v+ +
F30A10.8a 90 DDVIISVNGENLLDASHEEAVRALKRAGR-VVDLQVQYR 127
DUF355: domain 1 of 1, from 141 to 158: score 4.0, E = 1.4
*->vEgDeDkrkRreLLRkIGYKl<-*
vE D+D+r+R +R IG Kl
F30A10.8a 141 VEWDDDIRER---VRTIGLKL 158
CNH: domain 1 of 1, from 138 to 169: score 2.6, E = 9.9
*->letgeltqeladrvqtillnkirllssgrsls<-*
+e+ e++ ++++rv+ti+l++ + g ++
F30A10.8a 138 VENVEWDDDIRERVRTIGLKLAYVARAGIDAD 169
ELH: domain 1 of 1, from 130 to 175: score 2.7, E = 2.5
*->DmLltEqiqeReryLadLRqRLLekGKRssevsLlasdkdeeeRel<
Dm+ E i e + +d+R R+ G + + v+ + d d e+R l
F30A10.8a 130 DMMHRENIVENVEWDDDIRERVRTIGLKLAYVARAGIDADAEGRIL 175
-*
F30A10.8a - -
PH: domain 1 of 2, from 173 to 208: score 9.7, E = 0.26
*->ncFeirt.dr..tlllqaeseeerkeWvkaiqsair<-*
+ +e r+++++ +l ++++s+ee++ W++a+++++
F30A10.8a 173 RILEMRSpSGrySLAMRCSSSEEADGWFEALHACTT 208
PH: domain 2 of 2, from 228 to 340: score 41.0, E = 3.8e-10
*->vikeGwLlkks.....kswkkRyfvLfndvLlyykdsk......kkp
v ++Gw+ + ++++ + wk+++++L+n+ +l+y+ ++ + + ++p
F30A10.8a 228 VRHMGWIAEQVsengiSMWKPKFMTLTNSEILFYEAVPqlkaewAEP 274
kgsipLsgcqvek.pd...........kncFeirt.dr....tlllqaes
+ + pL +v+ +++++ + ++ ++ +F+ rt+++++ +t+ ++ e+
F30A10.8a 275 RLVRPLVATRVVQtSSrtapvikgltdVISFRMRTgTQqgvrTHTIRVET 324
eeerkeWvkaiqsair<-*
+e+ +Wv+a +
F30A10.8a 325 HAELARWVRAVVIGGY 340
7tm_2: domain 1 of 1, from 421 to 433: score 2.1, E = 8.5
*->fVavlYCflNgEV<-*
+V++l+ fl ++V
F30A10.8a 421 VVFILHSFLATKV 433