Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm2/seq/F32F2.1
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Query:  F32F2.1  CE18658   Guanine nucleotide exchange factor for Rho\/Rac\/Cdc42-like GTPases status:Partially_confirmed TR:Q9XXM9 protein_id:C

Scores for sequence family classification (score includes all domains):
Model          Description                              Score    E-value  N
--------       -----------                              -----    ------- ---
RhoGEF         RhoGEF domain                             81.2    1.4e-22   1
PH             PH domain                                 17.0     0.0023   1
Rota_NS6       Rotavirus non-structural protein 6         4.4        6.3   1
Ribosomal_S19e Ribosomal protein S19e                     3.3        7.9   1

Parsed for domains:
Model          Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------       ------- ----- -----    ----- -----      -----  -------
Ribosomal_S19e   1/1     224   236 ..   133   145 .]     3.3      7.9
Rota_NS6         1/1     360   382 ..     1    23 [.     4.4      6.3
RhoGEF           1/1     227   405 ..     1   207 []    81.2  1.4e-22
PH               1/1     498   535 ..    52    85 .]    17.0   0.0023

Alignments of top-scoring domains:
Ribosomal_S19e: domain 1 of 1, from 224 to 236: score 3.3, E = 7.9
                   *->LDrIAgqvldede<-*
                      LDrIA ++ld+++
     F32F2.1   224    LDRIAIELLDTER    236

Rota_NS6: domain 1 of 1, from 360 to 382: score 4.4, E = 6.3
                   *->mnrLqqRqlFLEnLLvGvnstFH<-*
                      + r+++  lFLEn+L  + st H
     F32F2.1   360    VQRILKYHLFLENILKNMPSTTH    382

RhoGEF: domain 1 of 1, from 227 to 405: score 81.2, E = 1.4e-22
                   *->vlkElleTEkkYvrdLeildnvymkpLreaaisskpvltpddietiF
                      +++Ell TE++Yv+dL +++++ym  L+e     k  +t d i+++F
     F32F2.1   227    IAIELLDTERTYVEDLNAVIKGYMDFLVEDR--EKLKVTLDAISSLF 271

                   sNiediyefhreFLkssLearisssqfedlDekkiepsaqrlGdlFlklk
                   ++ie i  f+++++   L+a+  +              +     +F ++
     F32F2.1   272 GCIERIFAFNKQLYN-QLDAADLD--------------CVKMSRCFVES- 305

                   epflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassntgAkd
                   +  ++ Y eYc+n+ + + +l +    +++p +a+ l+e+++  ++
     F32F2.1   306 SGKFEDYIEYCTNYHRMMSTLYH---LQQQPLVARALQERQLA-LNH--- 348

                   davkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedqpdredLkkaldl
                       l L+++LlkPvqRil+Y+L+L  +Lk  p+ +  ++  + k a +
     F32F2.1   349 ---SLQLSAYLLKPVQRILKYHLFLENILKNMPSTTHPEELIQVKRAHEV 395

                   lqdlaksiNe<-*
                   +   a +iN+
     F32F2.1   396 MTSQAARIND    405

PH: domain 1 of 1, from 498 to 535: score 17.0, E = 0.0023
                   *->kncFeirt.dr...tlllqaeseeerkeWvkaiqsair<-*
                      + +F++ + d+++ +++++a+s e++++W++ +++ +
     F32F2.1   498    PLSFQVLSfDNpraQYVFMASSMEQKRTWMQELKRMML    535



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