Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm2/seq/F35C5.6
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Query:  F35C5.6  CE15947   Lectin C-type domain short and long forms, von Willebrand factor type A domain status:Confirmed TR:O45444 protein_id:

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N
--------     -----------                                -----    ------- ---
vwa          von Willebrand factor type A domain         93.1    2.8e-28   1
DGOK         2-keto-3-deoxy-galactonokinase              12.0    0.00036   1
lectin_c     Lectin C-type domain                        11.0       0.22   1
2-Hacid_DH_C D-isomer specific 2-hydroxyacid dehydrog     2.0        1.9   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
DGOK           1/1     197   226 ..   273   298 .]    12.0  0.00036
vwa            1/1      60   242 ..     1   189 []    93.1  2.8e-28
lectin_c       1/1     281   343 ..     1    62 [.    11.0     0.22
2-Hacid_DH_C   1/1     390   404 ..     1    15 [.     2.0      1.9

Alignments of top-scoring domains:
DGOK: domain 1 of 1, from 197 to 226: score 12.0, E = 0.00036
                   *->LdaaGvavsAV....dGDeAvrAGLseiAr<-*
                      L   Gv vs+V  ++dGDeA +AGL  iA
     F35C5.6   197    LKSSGVVVSTVafdqDGDEALLAGLTNIAS    226

vwa: domain 1 of 1, from 60 to 242: score 93.1, E = 2.8e-28
                   *->DivFllDgSgSigeenrFekvkdfvkklveknld......igpdgtr
                      D+v ++D S+ ++ e+   ++   ++++++ n ++ +++  +p++tr
     F35C5.6    60    DVVVVVDNSKGMTNEG-ITEIAANIVTVFG-NGTrignqySDPRSTR 104

                   vglvqyssdvrtefsLndytskddllaai..lknlrylgGgTnNtgkALk
                    glv+y+++ +++++Ln  +s ddl + + +  n  ++++ ++ ++k++
     F35C5.6   105 LGLVTYNGRSTIVADLNLLQSIDDLYQSVfsTLNQVSNSDDSF-LAKGIG 153

                   yalenlfsstMlkngraagsRpenapkvlillTDGksndgpdve.aaaal
                   +a + l+s+      r++g R  n++++++++   +  +g++++ ++a +
     F35C5.6   154 AAENVLQSG------RTNGVRS-NYKRLVVVYASAYKGEGELDPiPVADR 196

                   rrk.giivfavGv..dadeeeLr.iasepeseghvfyvedfddlwlqlkd
                    +++g++v +v++++d de+ L +++   +++++ + ++++d       +
     F35C5.6   197 LKSsGVVVSTVAFdqDGDEALLAgLT---NIASPNYAFTSKDL------N 237

                   lqeal<-*
                   l+ +l
     F35C5.6   238 LVGEL    242

lectin_c: domain 1 of 1, from 281 to 343: score 11.0, E = 0.22
                   *->esktWaeAelaCqkegghAHLvsIqsaeEqsfvvafltsltkk....
                       s +W+ A+ aCq++  ++ L++  +   +    +fl +++ +++
     F35C5.6   281    ISSSWTAAKFACQNLAKNGFLAAEYDGQKH----NFLFRVAQNntaf 323

                   sntyaW.IGLtdintegtwv<-*
                      y+++IGL+++n+ ++w+
     F35C5.6   324 QAPYIYhIGLSYVNGGWNWQ    343

2-Hacid_DH_C: domain 1 of 1, from 390 to 404: score 2.0, E = 1.9
                   *->npvsVAEhvigliLs<-*
                      n++sVAE+ + ++ s
     F35C5.6   390    NAYSVAEYYMCEVAS    404



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