Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm3/seq/F46E10.10
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Query: F46E10.10 CE20820 lactate dehydrogenase status:Confirmed TR:Q9UAV5 protein_id:AAD14720.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
ldh lactate/malate dehydrogenase, NAD bind 176.8 3.6e-49 1
ldh_C lactate/malate dehydrogenase, alpha/be 127.2 3.1e-34 1
Rieske Rieske [2Fe-2S] domain 8.1 0.57 1
adh_short short chain dehydrogenase 7.1 0.58 1
Ribosomal_L7Ae Ribosomal protein L7Ae/L30e/S12e/Gadd4 6.8 1.2 1
Epimerase NAD dependent epimerase/dehydratase fa 5.3 1.1 1
DapB_N Dihydrodipicolinate reductase, N-termi 3.9 3.5 1
Zfx_Zfy_act Zfx / Zfy transcription activation reg 1.8 7.6 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
DapB_N 1/1 5 17 .. 1 13 [. 3.9 3.5
Epimerase 1/1 7 17 .. 1 11 [. 5.3 1.1
adh_short 1/1 3 25 .. 1 23 [. 7.1 0.58
Ribosomal_L7Ae 1/1 27 51 .. 75 100 .] 6.8 1.2
Zfx_Zfy_act 1/1 37 52 .. 1 16 [. 1.8 7.6
ldh 1/1 2 155 .. 1 156 [] 176.8 3.6e-49
Rieske 1/1 256 295 .. 77 111 .] 8.1 0.57
ldh_C 1/1 157 331 .. 1 181 [] 127.2 3.1e-34
Alignments of top-scoring domains:
DapB_N: domain 1 of 1, from 5 to 17: score 3.9, E = 3.5
*->irvavaGAaGRMG<-*
+rv+v+GAaG +G
F46E10.10 5 LRVLVTGAAGQIG 17
Epimerase: domain 1 of 1, from 7 to 17: score 5.3, E = 1.1
*->ILVTGGAGFIG<-*
+LVTG AG IG
F46E10.10 7 VLVTGAAGQIG 17
adh_short: domain 1 of 1, from 3 to 25: score 7.1, E = 0.58
*->tgKvaLvTGassGIGlaiAkrLa<-*
+ +LvTGa++ IG+ i+ r a
F46E10.10 3 APLRVLVTGAAGQIGYSIVIRIA 25
Ribosomal_L7Ae: domain 1 of 1, from 27 to 51: score 6.8, E = 1.2
*->GeacGkpvpdvsalaikdegdskilv<-*
G++ Gk+ p v+ + ++ +s+il+
F46E10.10 27 GTVFGKEQP-VELVLLDVPQCSNILE 51
Zfx_Zfy_act: domain 1 of 1, from 37 to 52: score 1.8, E = 7.6
*->edvviEdVhCpDIleE<-*
e v++ + +C+ Ile+
F46E10.10 37 ELVLLDVPQCSNILEG 52
ldh: domain 1 of 1, from 2 to 155: score 176.8, E = 3.6e-49
*->kkptKVaVvGAGGgVGsslAfalanlqgladEqpIiLvLvDinkamd
p +V V+GA+G++G+s + +a + ++++Eqp+ LvL+D+++ +
F46E10.10 2 SAPLRVLVTGAAGQIGYSIVIRIADGTVFGKEQPVELVLLDVPQCSN 48
kaeGvamDLqHgsaflsvpgiiggdqdyealkDaDvVvItAGvpqkPGeT
+eGv+++Lq++++++++ +++ d +++a+++ D++ +++++p+++G++
F46E10.10 49 ILEGVVFELQDCALPTLFSVVAVTD-EKSAFTGIDYAFLVGAMPRREGME 97
RlDLlnrNakIfksivpaiaksapd.aivlVvsNPVDiltyiawkvsKKa
R DLl++N+kIfks+++a+a++a+ + +v+Vv+NP+++++ ia+k++ a
F46E10.10 98 RKDLLAANVKIFKSQGKALAEYAKPtTKVIVVGNPANTNAFIAAKYA--A 145
Glpkervigs<-*
G ++ +++ +
F46E10.10 146 GKIPAKNFSA 155
Rieske: domain 1 of 1, from 256 to 295: score 8.1, E = 0.57
*->HGwrFdlstGrRaGklvggPapr.........plktypvleevg<-*
H w+F+ + G+ v++ p +++ + +++ + ++pv +e+g
F46E10.10 256 HDWHFGTKA----GQFVSMAVPSdgsygipqgLIFSFPVTIEGG 295
ldh_C: domain 1 of 1, from 157 to 331: score 127.2, E = 3.1e-34
*->TnLDtaRfrtllAeklgvkdPrsvhvyiiGEHGDsevPvWShAnvgG
T+LD++R+ ++lA k+g++ ++++v i+G+H+++++P+ hA+v
F46E10.10 157 TRLDHNRALAQLALKTGTTIGNVKNVIIWGNHSGTQFPDVTHATVNK 203
vpleslvkelgedsddeleelierVqdaAyeVIeaKaGaGsTtysiAlAl
+ e+ +++++ d +i +Vq+++ +Ie+++ s+++s+A+A+
F46E10.10 204 NGTETDAYAAVGDNAFLQGPFIATVQKRGGVIIEKRK--LSSAMSAAKAA 251
AriaeaiLrdtpEnrvlpvsvyldGfyGipddelvyfsvPvvLgrnGvee
+++ ++ ++t+ + +++ v +dG yGip + fs+Pv++ +G ++
F46E10.10 252 CDHIHDWHFGTKAGQFVSMAVPSDGSYGIPQG--LIFSFPVTIE-GGEWK 298
vvegllpLndeEreklekSadtLkkiiekgfafv<-*
+v g l+ +d+ + k++ + ++L ++++++++
F46E10.10 299 IVQG-LSFDDFAKGKIAATTKELEEERDDALKAC 331