Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm3/seq/F47E1.4
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Query:  F47E1.4  CE28398    status:Partially_confirmed TR:Q95ZT3 protein_id:AAK72060.1

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
OATP_C   Organic Anion Transporter Polypeptide (OATP)   196.3    4.8e-55   2
OATP_N   Organic Anion Transporter Polypeptide (OATP)   129.3    6.9e-35   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
OATP_C     1/2      24    95 ..     1    72 [.    60.6  1.5e-15
OATP_C     2/2     245   500 ..   119   410 .]   142.1  9.7e-39
OATP_N     1/1     570   702 ..     1   133 [.   129.3  6.9e-35

Alignments of top-scoring domains:
OATP_C: domain 1 of 2, from 24 to 95: score 60.6, E = 1.5e-15
                   *->YfkssITTiEKRFkipSstsGiIassyeIgnllliifVSYFGgrgHR
                      Y+ +++ +iE++F+++S +sG+++s  e g++ ++++ SYFG++g+R
     F47E1.4    24    YIYTALQSIERQFQMSSGISGLLVSATECGYIPCVVIMSYFGSKGNR 70

                   PRwIGiGlvlmalGslllaLPHFly<-*
                    RwIG G++lm++  l+l  P Fl+
     F47E1.4    71 SRWIGGGVLLMSITYLMLGTPNFLF    95

OATP_C: domain 2 of 2, from 245 to 500: score 142.1, E = 9.7e-39
                   *->ccqkehsstssmy.lllfvasQfllGIGaTPiytLGiSYiDDNvksk
                      ++ k + ++s+++++l+f+ s f+lG+G T    LGi+ +DDN k+k
     F47E1.4   245    ENSKCRAGSSNIWpFLVFFVSLFFLGVGRTIPWNLGIPLLDDNIKKK 291

                   nSPlyLgilfgstlamfGPAiGFllGSfcLrlYvDfgrvpleqikvsitp
                   + P+y g  +  +++++GP++G+l+GSf+++ Y   + +        +tp
     F47E1.4   292 HLPMYFGAIA--SIRVLGPICGYLIGSFSNQFYYTLQAPSG------LTP 333

                   tDPRWvGAWWLGFLvcGgllllsaiPfffFPKqLPkaqkrrknslrlkav
                       W+GAWWLGFL++G+l  + ++++ffFP+  + +   r       ++
     F47E1.4   334 VNQGWIGAWWLGFLLIGALSMFPSLLLFFFPQGKNSTLQLR------EIR 377

                   etereekeksngsksnpkakrslqdplvaiAgalavlqkLkvFpkvlkrl
                   e+++ +++      +++ +k                  k+k+F  + k+
     F47E1.4   378 ENKNGRAS------ESKPIKM-----------------KIKEFVISCKSV 404

                   lsNkvfmlviLaqvfessgiaGyaTFlPKyLEtQyglsasyAnmLtGvva
                   l  k+f+ + L  v+ ++++ Gy  FlPKyLEtQ+g++ +    ++ +
     F47E1.4   405 LGTKIFTGCLLGRVCDIFAFKGYVVFLPKYLETQFGIPQYLVHRYMSMFG 454

                   ipaaavGillGGliikKfklsargvaawnivvslvslagyiclffi<-*
                   ++ +++Gi lGG+i kKf+l+ r+ a + ++vs++ +  y +  fi
     F47E1.4   455 VFGFGLGIALGGFITKKFRLTGRQTALLMMIVSVLNITVYSSKIFI    500

OATP_N: domain 1 of 1, from 570 to 702: score 129.3, E = 6.9e-35
                   *->ncscnssavvgkGyCdpdCqnkfliFLilmaflsFfgalsavPllmi
                      +c+c +s+vv+k  C ++Cq     FL+++ ++sF++  + vP ++i
     F47E1.4   570    SCECVESGVVSKSFCQNKCQFSSILFLATVLLGSFVAGVAVVPDMLI 616

                   vLRcVppeeKSfAlGfqslliRlLGfIPaPIiFGalIDstCLlWgksCgG
                   +LR+V+   +S+++G+q ++i+l+G++P+ Ii+G +ID++C +W k+C+G
     F47E1.4   617 LLRSVDVGSRSLSMGLQGMAISLFGTLPSSIIWGLVIDTACRVWDKTCNG 666

                   krGaCrlYDndsfRyyiylglalfllfsslfdaivw<-*
                    +G+C++YD+d +R   +l++  ++++s+l d+ vw
     F47E1.4   667 ANGSCSIYDSDHLRIWMHLLYVGVRFISLLSDIYVW    702



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