Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm3/seq/F47E1.4
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Query: F47E1.4 CE28398 status:Partially_confirmed TR:Q95ZT3 protein_id:AAK72060.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
OATP_C Organic Anion Transporter Polypeptide (OATP) 196.3 4.8e-55 2
OATP_N Organic Anion Transporter Polypeptide (OATP) 129.3 6.9e-35 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
OATP_C 1/2 24 95 .. 1 72 [. 60.6 1.5e-15
OATP_C 2/2 245 500 .. 119 410 .] 142.1 9.7e-39
OATP_N 1/1 570 702 .. 1 133 [. 129.3 6.9e-35
Alignments of top-scoring domains:
OATP_C: domain 1 of 2, from 24 to 95: score 60.6, E = 1.5e-15
*->YfkssITTiEKRFkipSstsGiIassyeIgnllliifVSYFGgrgHR
Y+ +++ +iE++F+++S +sG+++s e g++ ++++ SYFG++g+R
F47E1.4 24 YIYTALQSIERQFQMSSGISGLLVSATECGYIPCVVIMSYFGSKGNR 70
PRwIGiGlvlmalGslllaLPHFly<-*
RwIG G++lm++ l+l P Fl+
F47E1.4 71 SRWIGGGVLLMSITYLMLGTPNFLF 95
OATP_C: domain 2 of 2, from 245 to 500: score 142.1, E = 9.7e-39
*->ccqkehsstssmy.lllfvasQfllGIGaTPiytLGiSYiDDNvksk
++ k + ++s+++++l+f+ s f+lG+G T LGi+ +DDN k+k
F47E1.4 245 ENSKCRAGSSNIWpFLVFFVSLFFLGVGRTIPWNLGIPLLDDNIKKK 291
nSPlyLgilfgstlamfGPAiGFllGSfcLrlYvDfgrvpleqikvsitp
+ P+y g + +++++GP++G+l+GSf+++ Y + + +tp
F47E1.4 292 HLPMYFGAIA--SIRVLGPICGYLIGSFSNQFYYTLQAPSG------LTP 333
tDPRWvGAWWLGFLvcGgllllsaiPfffFPKqLPkaqkrrknslrlkav
W+GAWWLGFL++G+l + ++++ffFP+ + + r ++
F47E1.4 334 VNQGWIGAWWLGFLLIGALSMFPSLLLFFFPQGKNSTLQLR------EIR 377
etereekeksngsksnpkakrslqdplvaiAgalavlqkLkvFpkvlkrl
e+++ +++ +++ +k k+k+F + k+
F47E1.4 378 ENKNGRAS------ESKPIKM-----------------KIKEFVISCKSV 404
lsNkvfmlviLaqvfessgiaGyaTFlPKyLEtQyglsasyAnmLtGvva
l k+f+ + L v+ ++++ Gy FlPKyLEtQ+g++ + ++ +
F47E1.4 405 LGTKIFTGCLLGRVCDIFAFKGYVVFLPKYLETQFGIPQYLVHRYMSMFG 454
ipaaavGillGGliikKfklsargvaawnivvslvslagyiclffi<-*
++ +++Gi lGG+i kKf+l+ r+ a + ++vs++ + y + fi
F47E1.4 455 VFGFGLGIALGGFITKKFRLTGRQTALLMMIVSVLNITVYSSKIFI 500
OATP_N: domain 1 of 1, from 570 to 702: score 129.3, E = 6.9e-35
*->ncscnssavvgkGyCdpdCqnkfliFLilmaflsFfgalsavPllmi
+c+c +s+vv+k C ++Cq FL+++ ++sF++ + vP ++i
F47E1.4 570 SCECVESGVVSKSFCQNKCQFSSILFLATVLLGSFVAGVAVVPDMLI 616
vLRcVppeeKSfAlGfqslliRlLGfIPaPIiFGalIDstCLlWgksCgG
+LR+V+ +S+++G+q ++i+l+G++P+ Ii+G +ID++C +W k+C+G
F47E1.4 617 LLRSVDVGSRSLSMGLQGMAISLFGTLPSSIIWGLVIDTACRVWDKTCNG 666
krGaCrlYDndsfRyyiylglalfllfsslfdaivw<-*
+G+C++YD+d +R +l++ ++++s+l d+ vw
F47E1.4 667 ANGSCSIYDSDHLRIWMHLLYVGVRFISLLSDIYVW 702