Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm3/seq/F49E2.5b
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Query: F49E2.5b CE31530 status:Confirmed TR:Q20625 protein_id:CAA86429.2
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
DUF612 Protein of unknown function, DUF612 944.5 1.3e-293 7
SUA5 SUA5 domain 10.7 0.081 2
Calcipressin Calcipressin 4.1 4 1
Bro-N BRO family, N-terminal domain 3.7 6.6 1
Rad21_Rec8_N N terminus of Rad21 / Rec8 like protein 3.2 8.1 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
Bro-N 1/1 34 44 .. 97 107 .] 3.7 6.6
DUF612 1/7 1 291 [. 1 291 [. 770.6 1.8e-239
Calcipressin 1/1 310 347 .. 238 275 .] 4.1 4
DUF612 2/7 346 382 .. 437 481 .. 21.8 1.9e-06
Rad21_Rec8_N 1/1 400 425 .. 106 136 .] 3.2 8.1
DUF612 3/7 431 454 .. 493 517 .] -1.9 43
DUF612 4/7 469 547 .. 434 517 .] 158.0 7.5e-49
SUA5 1/2 556 586 .. 1 38 [. 7.6 0.6
DUF612 5/7 548 597 .. 349 390 .. 7.3 0.063
SUA5 2/2 608 629 .. 1 22 [. 7.1 0.85
DUF612 6/7 600 646 .. 349 387 .. 2.3 2.1
DUF612 7/7 704 731 .. 489 517 .] -2.3 61
Alignments of top-scoring domains:
Bro-N: domain 1 of 1, from 34 to 44: score 3.7, E = 6.6
*->FqkWlteevLP<-*
F++Wl+ vLP
F49E2.5b 34 FRQWLLTAVLP 44
DUF612: domain 1 of 7, from 1 to 291: score 770.6, E = 1.8e-239
*->mRsPKsvRRPHiRqqLtnRRKnLGRvAKsqRnqFRqWLLtAvLPnsi
mRsPKsvRRPHiRqqLtnRRKnLGRvAKsqRnqFRqWLLtAvLPnsi
F49E2.5b 1 MRSPKSVRRPHIRQQLTNRRKNLGRVAKSQRNQFRQWLLTAVLPNSI 47
nDqRKEAFAsLELtEqPqqvEKvKKsEKKKAqKqiAKDHEAEqKvnAKKA
nDqRKEAFAsLELtEqPqqvEKvKKsEKKKAqKqiAKDHEAEqKvnAKKA
F49E2.5b 48 NDQRKEAFASLELTEQPQQVEKVKKSEKKKAQKQIAKDHEAEQKVNAKKA 97
AEKEARRAEAEAKKRAAqEEEHKqWKAEqERiqKEqEKKEADLKKLqAEK
AEKEARRAEAEAKKRAAqEEEHKqWKAEqERiqKEqEKKEADLKKLqAEK
F49E2.5b 98 AEKEARRAEAEAKKRAAQEEEHKQWKAEQERIQKEQEKKEADLKKLQAEK 147
KKEKAvKAEKAEKAEKtKKAstPAPvEEEivvKKvAnDRsAAPAPEPKtP
KKEKAvKAEKAEKAEKtKKAstPAPvEEEivvKKvAnDRsAAPAPEPKtP
F49E2.5b 148 KKEKAVKAEKAEKAEKTKKASTPAPVEEEIVVKKVANDRSAAPAPEPKTP 197
tntPAEPAEqvqEitGKKnKKnKKKsEsEAtAAPAsvEqvvEqPKvvtEE
tntPAEPAEqvqEitGKKnKKnKKKsEsEAtAAPAsvEqvvEqPKvvtEE
F49E2.5b 198 TNTPAEPAEQVQEITGKKNKKNKKKSESEATAAPASVEQVVEQPKVVTEE 247
PHqqAAPqEKKnKKnKRKsEsEnvPAAsEtPvEPvvEttPPAsE<-*
PHqqAAPqEKKnKKnKRKsEsEnvPAAsEtPvEPvvE P sE
F49E2.5b 248 PHQQAAPQEKKNKKNKRKSESENVPAASETPVEPVVENESPESE 291
Calcipressin: domain 1 of 1, from 310 to 347: score 4.1, E = 4
*->vceteidgeeaddlidqSgvsdtprpkakivqTarPpr<-*
++ ++i + ad+ i q +vs ++ +++++v+ P+
F49E2.5b 310 MGFSDIVTPKADEVITQDPVSAKQEVLPEHVPSEIPEE 347
DUF612: domain 2 of 7, from 346 to 382: score 21.8, E = 1.9e-06
*->EkPvqaAPvsKKPtADDsmDFLDFvtAKPeksEvveehieapaiv<-
E+Pv vsKKPtA DsmDFLDFvt K e eapa+v
F49E2.5b 346 EEPV---AVSKKPTA-DSMDFLDFVTPKTEAESTS----EAPAPV 382
*
F49E2.5b - -
Rad21_Rec8_N: domain 1 of 1, from 400 to 425: score 3.2, E = 8.1
*->kkaFrsgqkdfevdlPeenrtarinsnltlP<-*
+ a+++g ++ P++++t ++ns + l+
F49E2.5b 400 HVADVTGN----TLSPSQHSTPSPNS-VLLN 425
DUF612: domain 3 of 7, from 431 to 454: score -1.9, E = 43
*->aaenkKKnKKdKkKkesEkaveEsv<-*
++ k KK+Kk+ +sE +E+
F49E2.5b 431 SSKRKHHHKKNKKRTDSEM-SQEPS 454
DUF612: domain 4 of 7, from 469 to 547: score 158.0, E = 7.5e-49
*->kavEkPvqaAPvsKKPtADDsmDFLDFvtAKPeksEvveehieapai
k vEkPv APvsKKPtADD+mDFLDFvtAKPek+E+veehieap+i
F49E2.5b 469 KKVEKPV--APVSKKPTADDNMDFLDFVTAKPEKTESVEEHIEAPMI 513
vEvvkveeetAvaaenkKKnKKdKkKkesEkaveEsv<-*
vE+v++e+etA+aa++kKKnKK+K+Kk+sE+ Es+
F49E2.5b 514 VEPVHAENETAAAAGGKKKNKKNKNKKNSES---EST 547
SUA5: domain 1 of 2, from 556 to 586: score 7.6, E = 0.6
*->ITvEeiekvlGekilvkvveakkGleeaevpkaPGMKY<-*
+T+E +e+v+++k++++ ++a + aPG K+
F49E2.5b 556 VTPEIVEEVFEKKTITPSTAA-------AAAPAPGSKK 586
DUF612: domain 5 of 7, from 548 to 597: score 7.3, E = 0.063
*->PAA.PvEEvvEnvvEnvvEKsttPPAtEnK.......KKnKKDKKKs
PAA+Pv Ev +vE v EK t P t + +++KKnKK KK s
F49E2.5b 548 PAAePVKEVTPEIVEEVFEKKTITPSTAAAaapapgsKKNKKNKKNS 594
EsE<-*
EsE
F49E2.5b 595 ESE 597
SUA5: domain 2 of 2, from 608 to 629: score 7.1, E = 0.85
*->ITvEeiekvlGekilvkvveak<-*
+T+E +e+v+++k++++ +ea+
F49E2.5b 608 VTPEIVEEVFEKKTVTPSTEAA 629
[output cut off at A = 10 top alignments]