hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm3/seq/F52B5.2
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Query:  F52B5.2  CE24993   serine\/threonine kinase (2 domains) status:Partially_confirmed TR:Q20643 protein_id:CAA99854.2

Scores for sequence family classification (score includes all domains):
Model           Description                             Score    E-value  N
--------        -----------                             -----    ------- ---
pkinase         Protein kinase domain                   100.1    1.2e-26   2
Topoisomerase_I Eukaryotic DNA topoisomerase I, catal     7.5       0.41   1
RIO1            RIO1 family                               4.8        1.9   1

Parsed for domains:
Model           Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------        ------- ----- -----    ----- -----      -----  -------
RIO1              1/1      31    54 ..     1    32 [.     4.8      1.9
Topoisomerase_I   1/1      96   125 ..   147   181 ..     7.5     0.41
pkinase           1/2      97   156 ..    84   146 ..    58.5  3.9e-15
pkinase           2/2     180   292 ..   172   294 .]    41.3  2.2e-10

Alignments of top-scoring domains:
RIO1: domain 1 of 1, from 31 to 54: score 4.8, E = 1.9
                   *->nVYhAvsyaedgekdshsvlvevAvKiyrtgt<-*
                      +V+ A s  ++ ek       ev++K+++ g+
     F52B5.2    31    MVFLAES--GNEEK------KEVIIKFFKCGY    54

Topoisomerase_I: domain 1 of 1, from 96 to 125: score 7.5, E = 0.41
                   *->gddLFqtvdaG..G.rdrLdIlFtskLNkhLkefMpGL<-*
                      + dLF     G  G+r+rL+   +s   k++k +M+GL
     F52B5.2    96    ETDLF-----GilGdRQRLQ---PSTIQKYMKGLMEGL    125

pkinase: domain 1 of 2, from 97 to 156: score 58.5, E = 3.9e-15
                   *->GdLfdylrrnggplsekeakkialQilrGleYLHsngivHRDLKpeN
                      +dLf +l ++  +l +  ++k+++ + +Gl+++H++  +HRD+KpeN
     F52B5.2    97    TDLFGILGDRQ-RLQPSTIQKYMKGLMEGLQFIHRMDYIHRDIKPEN 142

                   ILldendgtvKiaDFG<-*
                   +L+d +  t++iaDFG
     F52B5.2   143 LLIDGE--TICIADFG    156

pkinase: domain 2 of 2, from 180 to 292: score 41.3, E = 2.2e-10
                   *->vilegrgysskvDvWSlGviLyElltggplfpgadlpaftggdevdq
                      + l +++ ++  D+W++ ++L  ++ g
     F52B5.2   180    I-LGYKENTKSMDIWAAACVLGAMFQG-------------------- 205

                   liifvlklPfsdelpktridpleelfriikrp..................
                            fs+      +++l+ +++i +  +++++++ ++ ++ +  +
     F52B5.2   206 ------SHLFSQ------NSNLQTIHAIRLLLgnhtketwpemdklplmq 243

                   ........glrlplpsncSeelkdLlkkcLnkDPskRpGsatakeilnhp
                   + + ++ +  ++ + +n+ +e+ dL++++ ++DP+kR+    a ++lnh
     F52B5.2   244 sielppvgEKTFSKIENITKEAADLMEQMMKYDPTKRL---MASQVLNHE 290

                   wf<-*
                   +f
     F52B5.2   291 YF    292

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