Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm3/seq/H34C03.2
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Query:  H34C03.2  CE19500   ubiquitin carboxy-terminal hydrolase status:Partially_confirmed TR:Q9TYY8 protein_id:AAC68977.1

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
UCH      Ubiquitin carboxyl-terminal hydrolase          398.0   2.5e-138   1
PHD      PHD-finger                                       7.0       0.46   1
DUF100   Protein of unknown function DUF100               6.9       0.31   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
DUF100     1/1      86   119 ..   336   369 .]     6.9     0.31
PHD        1/1     717   727 ..    41    51 .]     7.0     0.46
UCH        1/1     272   844 ..     1   456 []   398.0 2.5e-138

Alignments of top-scoring domains:
DUF100: domain 1 of 1, from 86 to 119: score 6.9, E = 0.31
                   *->RhGpFePHRLPseemEYttlPkvLekLedRFedl<-*
                      R G F      +e+++Yt +P++L k  +RF+ +
    H34C03.2    86    RNGSFFLKQRLAEQVDYTPVPEILFKRLERFYHI    119

PHD: domain 1 of 1, from 717 to 727: score 7.0, E = 0.46
                   *->gkWlCpeCtpk<-*
                      + W+Cp+C+ +
    H34C03.2   717    DSWYCPQCKKH    727

UCH: domain 1 of 1, from 272 to 844: score 398.0, E = 2.5e-138
                   *->egpvGLvNlGNTCYmNSvLQcLfhipelrdyllsnrhylprinnsnp
                      +g++GL NlGNTC+m S+ QcL++ p+lr+y+l n  y+++in++np
    H34C03.2   272    PGACGLSNLGNTCFMASAFQCLSNMPPLREYFLAN-TYQNDINEDNP 317

                   lgskgqllcaladlfkslqsnqyssppseaelslfeSnavsalnknskpe
                   lg +g l+ a   l+k ++s++y
    H34C03.2   318 LGTHGHLAMAVGELMKGMWSGDY--------------------------- 340

                   esisPtqflktlgkinpsFselegykliqQqDAqEfllfLLdgLhEDlNr
                   +si P++f++++g+++p F+   gy+   QqDA+E+ ++ LdgLhEDlNr
    H34C03.2   341 ASINPRKFKSIIGQFAPRFN---GYS---QQDAHELMAYVLDGLHEDLNR 384

                   vakkpyneehepgldlalee.ee.adelkdseaseeawknkstrneslis
                   ++kkpy             e++ +  +l+++e++   w+  + rn+s+i+
    H34C03.2   385 IKKKPY------------IEdSDeDAKLPEAEYAAKSWEVYKMRNDSIIV 422

                   dlFqGqlesrikCaleCgkvsvtyepFldLslpi................
                   d  +Gql+s+++C ++C+k+s++++pF +Lslp++++++  +++
    H34C03.2   423 DTLHGQLKSTLIC-PVCEKISIKFDPFGYLSLPLppkeqivkqtvivmfl 471

                   ..................................................
                   +++  + + + +++++ ++ ++   ++ +++++++    + +++ +++ +
    H34C03.2   472 trkwakfslgitdtttveeaerlmldklqpeqqhhfvffhvpsqyhddit 521

                   ..................................................
                     +++++ + ++++    + +++ + ++++     ++ +  ++ + +
    H34C03.2   522 mmrpgdrvrmpgrevyvaevehdlqvkgtrlfvaynriklvrsaslpmiy 571

                   ..................................................
                   + +++ + +++  +++  +++++   +++   + ++++++++++ +++++
    H34C03.2   572 slptgypltrgflndhvfsttkhffinpkavaelgggnsndddsmsgsns 621

                   ..................................................
                    +++++ +   ++++++ + + ++++++ + +++++++  ++  +   +
    H34C03.2   622 aderepyklfvgppgstaslpipptddpipfpdenshdiysnflqivfqw 671

                   .................kpkeasdspksLeecLkaFtkeEiLKviegenk
                   ++ +  ++ ++++  +++   ++++++ L+e L+ Ft++E+L   ++++
    H34C03.2   672 kdlkifnqykgnelierEMTVSTRRKVLLQETLDWFTTKEQL---GEQDS 718

                   yyCdkcgkkqeasKklkisrLPpiLtihLkRFsydgetssnimKindrve
                   +yC++c+k+++a+K+l +++LP+iL++hLkRF+y  + +    K+   v
    H34C03.2   719 WYCPQCKKHERATKQLALWKLPEILILHLKRFQYTKWSRE---KLTWEVV 765

                   fPleeLDlspylnqktnkeraaaeansleeeqqsvnadegnnqeeseest
                    P + LDl++ ++
    H34C03.2   766 IPVRGLDLTDKVA------------------------------------- 778

                   ksqeegenpptkYeLvaVvvHsGsslsgGHYiayikkldnnkWykFDDsv
                        ++    +Y+L+aV+ H+G slsgGHY+a  ++++++kW+ F+Ds
    H34C03.2   779 ----NPNHEKAIYDLIAVSRHYG-SLSGGHYTAIGYNDREQKWFDFNDS- 822

                   etVgdwkvvsvvseeevlkesgggtatseskrlkryrwAYiLFY<-*
                    +       ++  +   + es +               +YiL+Y
    H34C03.2   823 -SA------NPTYPPAEPYESSD---------------PYILVY    844



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