Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm3/seq/H35N03.1
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Query:  H35N03.1  CE31812  locus:exp-1 ion channel status:Partially_confirmed TR:Q9TZI5 protein_id:AAC67448.2

Scores for sequence family classification (score includes all domains):
Model          Description                              Score    E-value  N
--------       -----------                              -----    ------- ---
Neur_chan_LBD  Neurotransmitter-gated ion-channel lig   213.1    4.2e-60   1
Neur_chan_memb Neurotransmitter-gated ion-channel tra    10.8      0.024   3
ENT            ENT domain                                 4.6        7.1   1

Parsed for domains:
Model          Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------       ------- ----- -----    ----- -----      -----  -------
ENT              1/1      25    47 ..    86   110 .]     4.6      7.1
Neur_chan_LBD    1/1      21   235 ..     1   246 []   213.1  4.2e-60
Neur_chan_memb   1/3     242   258 ..     1    17 [.    -4.6  8.1e+02
Neur_chan_memb   2/3     269   311 ..    31    73 ..    33.7  4.4e-09
Neur_chan_memb   3/3     420   434 ..   277   291 .]   -10.2  2.8e+04

Alignments of top-scoring domains:
ENT: domain 1 of 1, from 25 to 47: score 4.6, E = 7.1
                   *->rellrrvnndetilrLreerkgsnk<-*
                      +++lrr++ d   ++ +e++kg+++
    H35N03.1    25    LQFLRRIQYDH--RQVPENEKGEAT    47

Neur_chan_LBD: domain 1 of 1, from 21 to 235: score 213.1, E = 4.2e-60
                   *->etrLlddLlentvsgYdkrvRPv.nggdvPpvtVsvgltlqqiisVd
                       +  l+ L +     Yd+r  P +  g+ + + V v++ +++i  V+
    H35N03.1    21    TRDFLQFLRRI---QYDHRQVPEnEKGE-A-TYVEVSVVVSNIRAVS 62

                   EknqdlttnvwlrqgqWtDpRLaWnpsdplddeddyggikslrlpsddeh
                   E+++d+ + +++r+ +W+DpRL+++          + + ++l l+++
    H35N03.1    63 EVTMDYALELFYRE-SWRDPRLQYDRKL-------FKNKTELALHES--- 101

                   dmldkIWlPDiflyN.qttskadgnhdvttpntnvrvypglkdGtVlwsp
                    + +++W PD+f+ N +  sk+ ++ +++ + +++r+     +G+ l+s
    H35N03.1   102 -YTNFLWFPDTFVPNaIA-SKNPQRNSIS-HRSLLRLDE---TGKLLYSR 145

                   paiykssCpmdltyFPFDqQnCslkFgSwtYngdevdlqwkdd......l
                   ++++   C mdlt+FPFD+Q C+l ++S++Y++d v+++w ++ ++  +l
    H35N03.1   146 RISLVCECTMDLTLFPFDKQLCKLGIESYGYTADHVVYKWSKGartaleL 195

                   eeidLpdFtengeWdlldvpakrnekpygcyselsgagLnklvYpditfy
                   ++i+LpdFt+ +  ++ +     +++ +g+ys+l+             +
    H35N03.1   196 KKIRLPDFTIQEAYVTSQ----MESYATGNYSRLY-------------VC 228

                   fvlrRkp<-*
                   fv++R
    H35N03.1   229 FVFSRSS    235

Neur_chan_memb: domain 1 of 3, from 242 to 258: score -4.6, E = 8.1e+02
                   *->liiPCvLIsfLswLvFy<-*
                      liiP++  ++ sw++ +
    H35N03.1   242    LIIPSTAVVITSWVSLW    258

Neur_chan_memb: domain 2 of 3, from 269 to 311: score 33.7, E = 4.4e-09
                   *->IsvLLtlTvFlllireilPkTSlvvPLigkYllFtMfvvtasi<-*
                      Is+ L+ T + ++ +e +P++S+++++++++ +++M+v++++i
    H35N03.1   269    ISIILAITFLIFSYNEMMPRVSYIKAMDIYLGVCFMIVFLSLI    311

Neur_chan_memb: domain 3 of 3, from 420 to 434: score -10.2, E = 2.8e+04
                   *->wiFpivfvlGTlgyf<-*
                      ++F++ fv++ l+yf
    H35N03.1   420    MLFFFGFVIFCLFYF    434



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