Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm3/seq/K02B12.5
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Query: K02B12.5 CE17993 ankyrin motif status:Partially_confirmed TR:Q21117 protein_id:CAB00035.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
ank Ankyrin repeat 82.2 1.3e-21 3
TPR TPR Domain 12.8 0.078 2
LRR Leucine Rich Repeat 7.0 4.1 2
UPF0061 Uncharacterized ACR, YdiU/UPF0061 family 4.1 1.3 1
hexokinase Hexokinase 3.1 7.7 1
LANC_like Lanthionine synthetase C-like protein 2.7 5.5 1
Bcl-2 Apoptosis regulator proteins, Bcl-2 family 2.4 3.6 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
TPR 1/2 70 103 .. 1 34 [] 4.5 19
hexokinase 1/1 226 247 .. 1 22 [. 3.1 7.7
LANC_like 1/1 311 319 .. 404 412 .] 2.7 5.5
TPR 2/2 405 434 .. 1 30 [. 8.5 1.4
ank 1/3 562 595 .. 1 33 [] 27.7 4.2e-06
ank 2/3 596 628 .. 1 33 [] 23.0 9.4e-05
Bcl-2 1/1 616 633 .. 1 18 [. 2.4 3.6
UPF0061 1/1 637 659 .. 609 631 .] 4.1 1.3
ank 3/3 646 678 .. 1 33 [] 31.5 3.5e-07
LRR 1/2 1072 1102 .. 1 25 [] 5.1 14
LRR 2/2 1103 1113 .. 1 11 [. 2.9 61
Alignments of top-scoring domains:
TPR: domain 1 of 2, from 70 to 103: score 4.5, E = 19
*->aeayynlGnaylklgkydeAieayekALeldPnn<-*
++ ++ ++ + + g+++ Ai +e+ +l +++
K02B12.5 70 VDKFNEAAHELKQIGDLESAISLCEEGSKLAREH 103
hexokinase: domain 1 of 1, from 226 to 247: score 3.1, E = 7.7
*->aelsqavdellaqFrvstEtLr<-*
a ++q++d+++ +rv++ ++r
K02B12.5 226 ARAMQLLDKTEGLLRVNDKSMR 247
LANC_like: domain 1 of 1, from 311 to 319: score 2.7, E = 5.5
*->qArFPgyEL<-*
+ArFP+ EL
K02B12.5 311 EARFPAHEL 319
TPR: domain 2 of 2, from 405 to 434: score 8.5, E = 1.4
*->aeayynlGnaylklgkydeAieayekALel<-*
+ay ++++y l ++ + +e ++ Lel
K02B12.5 405 LRAYQGMALVYSDLDEHSKSLEMFKNLLEL 434
ank: domain 1 of 3, from 562 to 595: score 27.7, E = 4.2e-06
*->dGnTPLHlAakrg.nlevvklLlqrGAdlnaqdd<-*
G+T LH Aa++ +n v+++L +rG +na+d+
K02B12.5 562 KGETVLHQAAMKSeNEAVIERLCRRGCKVNAKDN 595
ank: domain 2 of 3, from 596 to 628: score 23.0, E = 9.4e-05
*->dGnTPLHlAakrgnlevvklLlqrGAdlnaqdd<-*
G+TPL A+ ++++ v Ll++GA++na+
K02B12.5 596 GGWTPLSEAVAHNQYGNVLVLLRYGAEVNARSA 628
Bcl-2: domain 1 of 1, from 616 to 633: score 2.4, E = 3.6
*->LrraGdelekrveraFss<-*
L+r+G+e++ r + F+s
K02B12.5 616 LLRYGAEVNARSAESFMS 633
UPF0061: domain 1 of 1, from 637 to 659: score 4.1, E = 1.3
*->qDPssELdtseLkkLyeklrnPy<-*
q s EL+ s L L e+ n+y
K02B12.5 637 QNSSTELNHSRLTPLMEACTNGY 659
ank: domain 3 of 3, from 646 to 678: score 31.5, E = 3.5e-07
*->dGnTPLHlAakrgnlevvklLlqrGAdlnaqdd<-*
TPL+ A+ +g++++++lL+++ A+++++d
K02B12.5 646 SRLTPLMEACTNGYVDIAQLLIDNRASVDLRDS 678
LRR: domain 1 of 2, from 1072 to 1102: score 5.1, E = 14
*->nLreLdLsgNnlt......gslppdafsgLt<-*
n+++L+Lsg +l ++++ +++ p++f g++
K02B12.5 1072 NIESLNLSGIRLLanntsiDTIIPSVFIGMS 1102
[output cut off at A = 10 top alignments]