Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm3/seq/K08E3.1
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Query: K08E3.1 CE18864 tyrosinase status:Partially_confirmed TR:Q9XUS8 protein_id:CAB04594.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
tyrosinase Common central domain of tyrosinase 74.5 6.6e-20 2
ShTK ShTK domain 69.9 1.8e-19 2
Ribosomal_S27 Ribosomal protein S27a 8.1 1.8 1
SBP_bac_3 Bacterial extracellular solute-bindin 7.8 0.21 1
PH PH domain 5.9 3 1
PSI Plexin repeat 3.5 9.5 1
TIR TIR domain 3.4 5.8 1
Arthro_defensin Arthropod defensin 2.3 10 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
TIR 1/1 168 181 .. 138 151 .] 3.4 5.8
PH 1/1 168 184 .. 69 85 .] 5.9 3
SBP_bac_3 1/1 177 198 .. 211 233 .] 7.8 0.21
tyrosinase 1/2 204 238 .. 102 138 .. 28.0 6e-07
tyrosinase 2/2 335 435 .. 267 379 .] 52.2 1.1e-13
PSI 1/1 433 443 .. 1 11 [. 3.5 9.5
Arthro_defensin 1/1 455 476 .. 14 36 .] 2.3 10
ShTK 1/2 541 577 .. 1 44 [] 41.5 6.1e-11
ShTK 2/2 585 622 .. 1 44 [] 36.5 1.9e-09
Ribosomal_S27 1/1 615 624 .. 38 47 .] 8.1 1.8
Alignments of top-scoring domains:
TIR: domain 1 of 1, from 168 to 181: score 3.4, E = 5.8
*->qsdrikfWkkalya<-*
++d+ ++W++al+
K08E3.1 168 TEDERRRWHNALNT 181
PH: domain 1 of 1, from 168 to 184: score 5.9, E = 3
*->seeerkeWvkaiqsair<-*
+e+er++W +a++ ++r
K08E3.1 168 TEDERRRWHNALNTLKR 184
SBP_bac_3: domain 1 of 1, from 177 to 198: score 7.8, E = 0.21
*->kaLaelkadGtlkkiseKwgfgt<-*
+aL+ lk++G+++++s + +
K08E3.1 177 NALNTLKRNGEYDRLSRQH-LEV 198
tyrosinase: domain 1 of 2, from 204 to 238: score 28.0, E = 6e-07
*->vHesplFlpWHRwYLyfyEriLgklindptFAlPYWn<-*
+H++p FlpWHR YL ++E i +++ dpt+ +PYW+
K08E3.1 204 AHSGPGFLPWHREYLKRVE-IALRMV-DPTVFIPYWD 238
tyrosinase: domain 2 of 2, from 335 to 435: score 52.2, E = 1.1e-13
*->plHNpvHiwtGgntkynlPngisngedMgsfysaafDPIFylHHsNV
+ H +H+w Gg dM + ++a+ PIF+ HHs+V
K08E3.1 335 S-HSNIHLWIGG--------------DMKPPSTSANEPIFFMHHSFV 366
DRlWsiWkalggksFrtdfpeadwli.......shfrfydenpfppkrvk
D lW+ W l+++ r +++a+++++++ + hf+ ++ pfp+ +v+
K08E3.1 367 DYLWELWRQLQQP--RWLREQAYSADhptcanwQHFSYAPMRPFPY-LVN 413
vrDcfdtsrpklGYdYedqptpw<-*
+ ++ + ++++ Y Y++ +t +
K08E3.1 414 RDGLSNSYTDQM-YRYAPRATCS 435
PSI: domain 1 of 1, from 433 to 443: score 3.5, E = 9.5
*->nCsqhrqsCss<-*
+Cs++r++C+s
K08E3.1 433 TCSHQRPNCGS 443
Arthro_defensin: domain 1 of 1, from 455 to 476: score 2.3, E = 10
*->HClakGGrrGGyCnglkavCvCR<-*
HC++k r G C g+ + C+
K08E3.1 455 HCVSKI-RLNGNCRGFEQNDACY 476
ShTK: domain 1 of 2, from 541 to 577: score 41.5, E = 6.1e-11
*->tCvDyvDpasdCaawaslGefCnnppYyqdfmkenCpkTCGfCs<-*
+C +++++C +wa++G C++ p +fm+++C+ +C++C+
K08E3.1 541 DCY---NRMPCCDSWAKNGG-CQREP---EFMSQYCQASCNTCT 577
ShTK: domain 2 of 2, from 585 to 622: score 36.5, E = 1.9e-09
*->tCvDyvDpasdCaawaslGefCnnppYyqdfmkenCpkTCGfCs<-*
C+ D++++C aw++ C+ dfm+enC+ +CG Cs
K08E3.1 585 ACM---DRHVNCVAWKADKM-CSGKS--ADFMSENCRSSCGKCS 622
Ribosomal_S27: domain 1 of 1, from 615 to 624: score 8.1, E = 1.8
*->RqyCGKCgyT<-*
R +CGKC +T
K08E3.1 615 RSSCGKCSLT 624
[output cut off at A = 10 top alignments]