Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm3/seq/K08E5.2
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Query:  K08E5.2  CE28598   Yeast ORF YCR37C status:Partially_confirmed SW:Q21339 protein_id:CAA83225.2

Scores for sequence family classification (score includes all domains):
Model         Description                               Score    E-value  N
--------      -----------                               -----    ------- ---
Na_sulph_symp Sodium:sulfate symporter transmembrane    255.1    9.5e-73   1
DUF590        Protein of unknown function, DUF590         6.8        0.6   1
DUF230        Poxvirus proteins of unknown function       4.4        7.2   1

Parsed for domains:
Model         Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------      ------- ----- -----    ----- -----      -----  -------
DUF230          1/1      92   108 ..   124   140 .]     4.4      7.2
DUF590          1/1     297   318 ..   266   287 .]     6.8      0.6
Na_sulph_symp   1/1       4   478 ..    30   585 .]   255.1  9.5e-73

Alignments of top-scoring domains:
DUF230: domain 1 of 1, from 92 to 108: score 4.4, E = 7.2
                   *->pfviplgliaviflila<-*
                      p++i lg++ v++l+++
     K08E5.2    92    PKWIMLGFMTVTALLSS    108

DUF590: domain 1 of 1, from 297 to 318: score 6.8, E = 0.6
                   *->llswvIPdvPrevrdqirReky<-*
                      +l +v+P++  +++++i++e++
     K08E5.2   297    FLLFVLPSERPDLATYIKKEDL    318

Na_sulph_symp: domain 1 of 1, from 4 to 478: score 255.1, E = 9.5e-73
                   *->pkAWhlfAifiamIvGlIlePvPlgviALiaislsavltgtlsfene
                      +++W +++     +v +  e  Pl+v+A+ +++l+++++  ++
     K08E5.2     4    RHEWKCAYCVCIIAVYWMSEVMPLAVTAMLPVVLFPLVGVLDA---- 46

                   elaqpGFkatakalswalsGFsntttWLvfgAFflaaGfekTGLGkRIAL
                                   +  ++ n+t+ L++g+++ aa++ek  L++R+AL
     K08E5.2    47 --------------NTTAKEYMNDTNFLFIGGLIMAAAVEKCDLHERVAL 82

                   vlvkaiGkrtalLgLGYalVfsdLlLaPaiPSnRTARaGGIifPviksLp
                    +++ +G+ +  + LG+++V++ L+  ++++++ TA++++I   v+++L
     K08E5.2    83 SVLRCVGSEPKWIMLGFMTVTALLSSFISNTAT-TAMMVPIGQSVVQQLI 131

                   vsqnVEeGlfgStpekgEpsPQKEvtKlDNGQalpvpsapEdehltQese
                           +f+  p +g                       E+ +l
     K08E5.2   132 S-------SFQHHPTNG-----------------------ERGRL---GC 148

                   rkiGayLmltvyqstsItSamFLTAmApNlLllglmnkLFPilGneisWa
                   +k + +L l+++ ++ I++ ++ T++  Nl+ lg+ + LFP +   ++ +
     K08E5.2   149 KKMATGLVLSICFAANIGGTGTATGTPSNLVMLGQLSALFPKVDGSLNYV 198

                   sWflAAlppGiilLllvPLllYvLyPPeiksspFGigEkeeEqqQdakri
                    W  +A p+++++L++++  l   ++    +++            ++ +
     K08E5.2   199 TWIFFAYPLMLLCLFVAWMTLVSFFLRDAPEKD-----------EAVTEM 237

                   AkteLkemGPmsfrEktllvlflLlLlLWiFggPGFFlGWGnlvslgakG
                    kt++ e+ +m+ +Ek ++v f +lL LW+F++PG  +G G   + ga
     K08E5.2   238 LKTRYNELPRMTYAEKSVFVCFCILLSLWVFRNPGVVPGFGVFFKKGA-- 285

                   esMidAttVAiivlvlllllrskiPGLt.....QDPenPGkLKAPpaivt
                        ++t A iv  ll++l+s  P L +  ++ D ++ G       +++
     K08E5.2   286 ---YTDATSAMIVAFLLFVLPSERPDLAtyikkEDLKKRGC------LMD 326

                   WkKDivknktAWNTliwlGgLiaLAggLnksGfieWlGnklvtllslagl
                   Wk  +++++ +W ++++lGg++aLA g ++sG++  +Gn+l+++ +
     K08E5.2   327 WK--TMQETFPWSVVLLLGGGFALAAGVKESGLSLLIGNSLSSIEH---- 370

                   splmafivLilllylsHYfFASatAhtaAmlPiflavaqaipGaPpllla
                    pl  +  L  l   + +   S+t + ++++Pi +++aq + G+ p+ l+
     K08E5.2   371 LPLWILQLLTMLIAMVITNICSNTVTASIFVPIVATLAQRA-GHHPFTLM 419

                   LlLafassLgGflTPYgtGPnpiyFGsGyvkvkdwWrlGfilsIigliiw
                   L+ ++ass++ f+ P+gt+Pn+i+FGsG vkv+d++ +G   +Ii+l ++
     K08E5.2   420 LPTTLASSFA-FIFPVGTPPNAIVFGSGMVKVSDMAFVG---GIISLELL 465

                   llvGalWWkaLglw<-*
                   +l+  l+ + ++++
     K08E5.2   466 VLTV-LYMNSIAYL    478



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